Project

PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

Navigation
Downloads

Results for Nkx3-2

Z-value: 0.92

Motif logo

Transcription factors associated with Nkx3-2

Gene Symbol Gene ID Gene Info
ENSMUSG00000049691.9 Nkx3-2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nkx3-2mm39_v1_chr5_-_41921834_419218440.038.2e-01Click!

Activity profile of Nkx3-2 motif

Sorted Z-values of Nkx3-2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx3-2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image
Promoter Score Transcript Gene Gene Info
chr11_-_120622770 25.25 ENSMUST00000154565.2
ENSMUST00000026148.9
carbonyl reductase 2
chr15_+_75468473 8.34 ENSMUST00000189944.7
ENSMUST00000023243.11
GPI-anchored HDL-binding protein 1
chr15_+_75468494 6.24 ENSMUST00000189874.2
GPI-anchored HDL-binding protein 1
chr9_+_122980006 4.70 ENSMUST00000026890.6
C-type lectin domain family 3, member b
chr11_+_43365103 4.43 ENSMUST00000173002.8
ENSMUST00000057679.10
C1q and tumor necrosis factor related protein 2
chr6_-_133830613 3.80 ENSMUST00000203168.2
ENSMUST00000048032.5
kidney androgen regulated protein
chr9_+_48073296 3.58 ENSMUST00000216998.2
ENSMUST00000215780.2
neurexophilin and PC-esterase domain family, member 4
chr1_-_162726234 3.55 ENSMUST00000111510.8
ENSMUST00000045902.13
flavin containing monooxygenase 2
chr11_-_69686756 3.39 ENSMUST00000045971.9
cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)
chr11_-_101877832 3.34 ENSMUST00000107173.9
ENSMUST00000107172.8
dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)
chr8_+_46338498 3.33 ENSMUST00000034053.7
PDZ and LIM domain 3
chr8_+_46338557 3.32 ENSMUST00000210422.2
PDZ and LIM domain 3
chr4_-_141325517 3.28 ENSMUST00000131317.8
ENSMUST00000006381.11
ENSMUST00000129602.8
filamin binding LIM protein 1
chr4_+_148085179 3.26 ENSMUST00000103230.5
natriuretic peptide type A
chr8_+_104828253 3.19 ENSMUST00000034339.10
cadherin 5
chr15_+_34306812 3.19 ENSMUST00000226766.2
ENSMUST00000163455.9
ENSMUST00000022947.7
ENSMUST00000228570.2
ENSMUST00000227759.2
matrilin 2
chrX_-_96420756 3.17 ENSMUST00000113832.2
ENSMUST00000037353.10
ectodysplasin A2 receptor
chr10_+_116111441 3.07 ENSMUST00000218553.2
protein tyrosine phosphatase, receptor type, B
chr7_-_67409432 2.99 ENSMUST00000208815.2
ENSMUST00000074233.12
ENSMUST00000208231.2
ENSMUST00000051389.10
synemin, intermediate filament protein
chr10_+_127350820 2.92 ENSMUST00000035735.11
Ndufa4, mitochondrial complex associated like 2
chr9_-_44646487 2.87 ENSMUST00000034611.15
pleckstrin homology like domain, family B, member 1
chr3_-_81981946 2.79 ENSMUST00000029635.14
ENSMUST00000193597.2
guanylate cyclase 1, soluble, beta 1
chr17_-_82045800 2.77 ENSMUST00000235015.2
ENSMUST00000163123.3
solute carrier family 8 (sodium/calcium exchanger), member 1
chr17_+_44114894 2.75 ENSMUST00000044895.13
regulator of calcineurin 2
chr9_-_58220469 2.72 ENSMUST00000061799.10
lysyl oxidase-like 1
chr7_-_48493388 2.52 ENSMUST00000167786.4
cysteine and glycine-rich protein 3
chr5_+_149335214 2.39 ENSMUST00000093110.12
mesenteric estrogen dependent adipogenesis
chr8_-_86107593 2.37 ENSMUST00000122452.8
myosin light chain kinase 3
chrX_-_151820545 2.33 ENSMUST00000051484.5
MAGE family member H1
chr17_-_43854530 2.30 ENSMUST00000178772.3
ankyrin repeat domain 66
chr3_-_57483330 2.26 ENSMUST00000120977.2
WW domain containing transcription regulator 1
chr3_-_57483175 2.20 ENSMUST00000029380.14
WW domain containing transcription regulator 1
chr15_+_97990431 2.19 ENSMUST00000229280.2
ENSMUST00000163507.8
ENSMUST00000230445.2
phosphofructokinase, muscle
chr4_-_151129020 2.19 ENSMUST00000103204.11
period circadian clock 3
chrX_-_158921370 2.14 ENSMUST00000033662.9
pyruvate dehydrogenase E1 alpha 1
chr3_+_89344006 2.12 ENSMUST00000038942.10
ENSMUST00000130858.8
ENSMUST00000146630.8
ENSMUST00000145753.2
pre B cell leukemia transcription factor interacting protein 1
chr3_-_37473715 2.12 ENSMUST00000138949.2
ENSMUST00000149449.8
ENSMUST00000108118.9
ENSMUST00000108117.3
ENSMUST00000099130.9
ENSMUST00000052645.13
nudix (nucleoside diphosphate linked moiety X)-type motif 6
chr6_+_21985902 2.08 ENSMUST00000115383.9
cadherin-like and PC-esterase domain containing 1
chr16_+_57173456 2.07 ENSMUST00000159816.8
filamin A interacting protein 1-like
chr2_+_69500444 2.06 ENSMUST00000100050.4
kelch-like 41
chr7_+_127503251 1.98 ENSMUST00000071056.14
branched chain ketoacid dehydrogenase kinase
chr8_-_76133212 1.97 ENSMUST00000212864.2
predicted gene 10358
chr4_-_58206596 1.95 ENSMUST00000042850.9
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr15_-_5093222 1.94 ENSMUST00000110689.5
complement component 7
chr8_-_86112938 1.93 ENSMUST00000137290.2
myosin light chain kinase 3
chr1_+_135764092 1.91 ENSMUST00000188028.7
ENSMUST00000178204.8
ENSMUST00000190451.7
ENSMUST00000189732.7
ENSMUST00000189355.7
troponin T2, cardiac
chr3_-_30194559 1.89 ENSMUST00000108271.10
MDS1 and EVI1 complex locus
chr15_-_98193995 1.88 ENSMUST00000023722.12
ENSMUST00000169721.3
zinc finger protein 641
chr10_-_13350106 1.87 ENSMUST00000105545.12
phosphatase and actin regulator 2
chr18_-_36648850 1.85 ENSMUST00000025363.7
heparin-binding EGF-like growth factor
chr6_+_113449237 1.85 ENSMUST00000204447.3
interleukin 17 receptor C
chr7_+_113365356 1.79 ENSMUST00000084696.6
spondin 1, (f-spondin) extracellular matrix protein
chr8_+_27575611 1.78 ENSMUST00000178514.8
ENSMUST00000033876.14
adhesion G protein-coupled receptor A2
chr14_-_79539063 1.78 ENSMUST00000022595.8
regulator of cell cycle
chr4_-_148021159 1.78 ENSMUST00000105712.2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr6_+_97187650 1.77 ENSMUST00000044681.7
ADP-ribosylation factor-like 6 interacting protein 5
chr10_+_79824418 1.75 ENSMUST00000004784.11
ENSMUST00000105374.2
calponin 2
chr9_-_103980200 1.74 ENSMUST00000188000.2
atypical chemokine receptor 4
chr4_+_149670889 1.70 ENSMUST00000105691.8
calsyntenin 1
chr14_+_52131067 1.70 ENSMUST00000047726.12
solute carrier family 39 (zinc transporter), member 2
chr15_+_11064887 1.68 ENSMUST00000061318.9
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 12
chr16_+_21023505 1.62 ENSMUST00000006112.7
Eph receptor B3
chr5_-_8417982 1.61 ENSMUST00000088761.11
ENSMUST00000115386.8
ENSMUST00000050166.14
ENSMUST00000046838.14
ENSMUST00000115388.9
ENSMUST00000088744.12
ENSMUST00000115385.2
a disintegrin and metallopeptidase domain 22
chr1_+_179788675 1.59 ENSMUST00000076687.12
ENSMUST00000097450.10
ENSMUST00000212756.2
CDC42 binding protein kinase alpha
chr8_+_95498822 1.58 ENSMUST00000211956.2
ENSMUST00000211947.2
chemokine (C-X3-C motif) ligand 1
chr18_+_23885390 1.58 ENSMUST00000170802.8
ENSMUST00000155708.8
ENSMUST00000118826.9
microtubule-associated protein, RP/EB family, member 2
chr16_-_38533597 1.56 ENSMUST00000023487.5
Rho GTPase activating protein 31
chr9_-_43027809 1.53 ENSMUST00000216126.2
ENSMUST00000213544.2
ENSMUST00000061833.6
TLC domain containing 5
chr5_-_31311496 1.51 ENSMUST00000201353.4
ENSMUST00000200864.4
ENSMUST00000200833.4
ENSMUST00000201491.2
ENSMUST00000200744.4
ENSMUST00000202241.4
ENSMUST00000154241.8
MpV17 mitochondrial inner membrane protein
chr8_-_123404811 1.50 ENSMUST00000006525.14
ENSMUST00000064674.13
CBFA2/RUNX1 translocation partner 3
chr11_+_110956980 1.49 ENSMUST00000042970.3
potassium inwardly-rectifying channel, subfamily J, member 2
chr12_-_103660946 1.49 ENSMUST00000118101.2
serine (or cysteine) peptidase inhibitor, clade A, member 1F
chr2_-_35351259 1.48 ENSMUST00000113001.9
ENSMUST00000113002.9
glycoprotein galactosyltransferase alpha 1, 3
chr7_-_79492091 1.47 ENSMUST00000049004.8
alanyl (membrane) aminopeptidase
chr15_-_102533494 1.44 ENSMUST00000184077.8
ENSMUST00000184906.8
ENSMUST00000169033.8
activating transcription factor 7
chr8_-_41494890 1.43 ENSMUST00000051379.14
mitochondrial tumor suppressor 1
chr11_+_118324652 1.43 ENSMUST00000106286.3
C1q and tumor necrosis factor related protein 1
chr11_+_35011953 1.41 ENSMUST00000069837.4
slit guidance ligand 3
chr5_+_30360246 1.41 ENSMUST00000026841.15
ENSMUST00000123980.8
ENSMUST00000114783.6
ENSMUST00000114786.8
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
chr11_+_87471867 1.39 ENSMUST00000018544.12
ENSMUST00000063156.11
ENSMUST00000107960.8
septin 4
chr2_-_35351408 1.39 ENSMUST00000102794.8
glycoprotein galactosyltransferase alpha 1, 3
chr4_-_119031050 1.35 ENSMUST00000052715.10
ENSMUST00000179290.8
ENSMUST00000154226.2
zinc finger protein 691
chr8_-_123278054 1.35 ENSMUST00000156333.9
ENSMUST00000067252.14
piezo-type mechanosensitive ion channel component 1
chr16_+_4704166 1.34 ENSMUST00000230990.2
mahogunin, ring finger 1
chr8_+_75940572 1.33 ENSMUST00000139848.8
RASD family, member 2
chr1_+_43769750 1.31 ENSMUST00000027217.9
ECRG4 augurin precursor
chr10_-_12702674 1.26 ENSMUST00000219130.2
utrophin
chr5_+_136112765 1.25 ENSMUST00000042135.14
RAS p21 protein activator 4
chr2_+_120459593 1.24 ENSMUST00000180041.9
START domain containing 9
chr7_-_109559593 1.22 ENSMUST00000106722.2
DENN/MADD domain containing 5A
chr7_-_109559671 1.19 ENSMUST00000080437.13
DENN/MADD domain containing 5A
chr10_-_12745109 1.18 ENSMUST00000218635.2
utrophin
chr11_+_51654511 1.16 ENSMUST00000020653.6
secretion associated Ras related GTPase 1B
chr3_+_14545751 1.16 ENSMUST00000037321.8
ENSMUST00000120484.8
ENSMUST00000120801.2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr18_+_50186349 1.15 ENSMUST00000148159.3
tumor necrosis factor, alpha-induced protein 8
chr2_-_164246526 1.14 ENSMUST00000109359.8
ENSMUST00000109358.8
ENSMUST00000103103.10
matrilin 4
chr4_-_130253703 1.13 ENSMUST00000134159.3
zinc finger, CCHC domain containing 17
chr9_+_106325828 1.12 ENSMUST00000217496.2
abhydrolase domain containing 14b
chr9_-_35111172 1.11 ENSMUST00000176021.8
ENSMUST00000176531.8
ENSMUST00000176685.8
ENSMUST00000177129.8
toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
chr4_-_148021217 1.11 ENSMUST00000019199.14
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr19_-_4062656 1.10 ENSMUST00000134479.8
ENSMUST00000128787.8
ENSMUST00000237862.2
ENSMUST00000236203.2
ENSMUST00000133474.8
NADH:ubiquinone oxidoreductase core subunit V1
chr7_+_26821266 1.10 ENSMUST00000206552.2
cytochrome P450, family 2, subfamily f, polypeptide 2
chr4_-_40239700 1.08 ENSMUST00000142055.2
DEAD/H box helicase 58
chr5_+_136112817 1.08 ENSMUST00000100570.10
RAS p21 protein activator 4
chr12_-_103660916 1.07 ENSMUST00000117053.8
serine (or cysteine) peptidase inhibitor, clade A, member 1F
chrX_+_149829131 1.05 ENSMUST00000112685.8
FYVE, RhoGEF and PH domain containing 1
chr1_+_17797257 1.04 ENSMUST00000159958.8
ENSMUST00000160305.8
ENSMUST00000095075.5
cysteine-rich secretory protein LCCL domain containing 1
chr3_+_123061094 1.03 ENSMUST00000047923.12
ENSMUST00000200333.2
Sec24 related gene family, member D (S. cerevisiae)
chr6_-_92511836 1.03 ENSMUST00000113446.8
prickle planar cell polarity protein 2
chr14_+_54598283 1.02 ENSMUST00000000985.7
oxidase assembly 1-like
chr19_-_4062738 1.02 ENSMUST00000136921.2
ENSMUST00000042497.14
NADH:ubiquinone oxidoreductase core subunit V1
chr9_+_69902697 1.01 ENSMUST00000165389.8
BCL2/adenovirus E1B interacting protein 2
chr6_+_83011154 1.01 ENSMUST00000000707.9
ENSMUST00000101257.4
lysyl oxidase-like 3
chr2_+_20742115 1.00 ENSMUST00000114606.8
ENSMUST00000114608.3
enhancer trap locus 4
chr17_+_36134450 1.00 ENSMUST00000172846.2
flotillin 1
chr9_+_57847387 0.99 ENSMUST00000043059.9
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr16_+_57173632 0.98 ENSMUST00000099667.3
filamin A interacting protein 1-like
chr17_+_37313502 0.95 ENSMUST00000173921.8
ENSMUST00000172580.8
zinc finger protein 57
chr15_-_102533357 0.94 ENSMUST00000183765.2
activating transcription factor 7
chr1_-_168259839 0.93 ENSMUST00000188912.7
pre B cell leukemia homeobox 1
chr13_-_35147771 0.91 ENSMUST00000164155.2
ENSMUST00000021853.12
enoyl-Coenzyme A delta isomerase 3
chr16_+_4704103 0.91 ENSMUST00000023159.10
ENSMUST00000070658.16
ENSMUST00000229038.2
mahogunin, ring finger 1
chr13_-_104953631 0.91 ENSMUST00000154165.2
CWC27 spliceosome-associated protein
chr8_+_105066924 0.91 ENSMUST00000212081.2
CKLF-like MARVEL transmembrane domain containing 3
chrX_-_135104589 0.89 ENSMUST00000066819.11
transcription elongation factor A (SII)-like 5
chr7_-_30855295 0.89 ENSMUST00000186723.3
GRAM domain containing 1A
chr6_-_72357398 0.88 ENSMUST00000101285.10
ENSMUST00000074231.6
vesicle-associated membrane protein 5
chr7_-_110581652 0.87 ENSMUST00000005751.13
inositol 1,4,5-triphosphate receptor associated 1
chr8_+_75941130 0.86 ENSMUST00000132133.2
RASD family, member 2
chr6_-_21851827 0.86 ENSMUST00000202353.2
ENSMUST00000134635.2
ENSMUST00000123116.8
ENSMUST00000120965.8
ENSMUST00000143531.2
tetraspanin 12
chr2_+_122146153 0.84 ENSMUST00000099461.4
dual oxidase 1
chr4_+_63477018 0.84 ENSMUST00000077709.11
transmembrane protein 268
chr11_+_49141410 0.83 ENSMUST00000129588.2
mannoside acetylglucosaminyltransferase 1
chr6_+_83112793 0.82 ENSMUST00000065512.11
rhotekin
chr7_+_43228999 0.82 ENSMUST00000058104.8
ENSMUST00000205769.2
zinc finger protein 719
chr5_-_30360113 0.82 ENSMUST00000156859.3
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
chr9_-_100916946 0.82 ENSMUST00000035116.12
propionyl Coenzyme A carboxylase, beta polypeptide
chr1_-_75110511 0.81 ENSMUST00000027405.6
solute carrier family 23 (nucleobase transporters), member 3
chr15_+_54434576 0.79 ENSMUST00000025356.4
mal, T cell differentiation protein 2
chr2_+_128540822 0.78 ENSMUST00000014505.5
MER proto-oncogene tyrosine kinase
chr14_-_54648057 0.77 ENSMUST00000200545.2
ENSMUST00000227967.2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr8_-_94825556 0.77 ENSMUST00000034206.6
Bardet-Biedl syndrome 2 (human)
chr9_+_40180726 0.77 ENSMUST00000171835.9
sodium channel, voltage-gated, type III, beta
chr11_-_94440025 0.77 ENSMUST00000040487.4
radical S-adenosyl methionine domain containing 1
chr2_+_125876883 0.76 ENSMUST00000110442.2
fibroblast growth factor 7
chr5_-_113163339 0.75 ENSMUST00000197776.2
ENSMUST00000065167.9
G protein-coupled receptor kinase 3
chr1_-_168259710 0.74 ENSMUST00000072863.6
pre B cell leukemia homeobox 1
chr19_-_24178000 0.74 ENSMUST00000233658.3
tight junction protein 2
chr9_+_106325860 0.73 ENSMUST00000185527.3
abhydrolase domain containing 14b
chr11_-_72380730 0.72 ENSMUST00000045303.10
spinster homolog 2
chr18_+_37580692 0.71 ENSMUST00000052387.5
protocadherin beta 14
chr12_+_112940086 0.70 ENSMUST00000165079.8
ENSMUST00000221500.2
ENSMUST00000221104.2
ENSMUST00000002880.7
ENSMUST00000222209.2
BTB (POZ) domain containing 6
chrX_-_99669507 0.69 ENSMUST00000059099.7
PDZ domain containing 11
chr9_+_122863791 0.68 ENSMUST00000026893.6
ENSMUST00000215247.2
transglutaminase 4 (prostate)
chr12_+_51737775 0.67 ENSMUST00000218820.2
ENSMUST00000021338.10
adaptor-related protein complex AP-4, sigma 1
chr11_+_69891398 0.67 ENSMUST00000019362.15
ENSMUST00000190940.2
dishevelled segment polarity protein 2
chr19_-_60862964 0.66 ENSMUST00000025961.7
peroxiredoxin 3
chr14_-_121742659 0.66 ENSMUST00000088386.8
solute carrier family 15 (oligopeptide transporter), member 1
chr14_-_119336809 0.65 ENSMUST00000156203.8
UDP-glucose glycoprotein glucosyltransferase 2
chr9_-_56151334 0.65 ENSMUST00000188142.7
pseudopodium-enriched atypical kinase 1
chr1_+_63769772 0.64 ENSMUST00000027103.7
FAST kinase domains 2
chr2_-_36026785 0.64 ENSMUST00000028251.10
RNA binding motif protein 18
chr18_+_74401322 0.63 ENSMUST00000224047.2
methyl-CpG binding domain protein 1
chr17_+_15616464 0.62 ENSMUST00000055352.8
family with sequence similarity 120, member B
chr5_+_32616187 0.62 ENSMUST00000015100.15
protein phosphatase 1 catalytic subunit beta
chr2_+_32253016 0.61 ENSMUST00000132028.8
ENSMUST00000136079.8
CDKN1A interacting zinc finger protein 1
chr7_+_86175967 0.61 ENSMUST00000071112.4
olfactory receptor 297
chr8_-_69541852 0.60 ENSMUST00000037478.13
ENSMUST00000148856.2
solute carrier family 18 (vesicular monoamine), member 1
chr11_+_97594220 0.60 ENSMUST00000103147.5
proteasome (prosome, macropain) subunit, beta type 3
chr1_+_39940189 0.59 ENSMUST00000191761.6
ENSMUST00000193682.6
ENSMUST00000195860.6
ENSMUST00000195259.6
ENSMUST00000195636.6
ENSMUST00000192509.6
mitogen-activated protein kinase kinase kinase kinase 4
chr14_-_54647647 0.59 ENSMUST00000228488.2
ENSMUST00000195970.5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr7_-_19093383 0.59 ENSMUST00000047036.10
CD3E antigen, epsilon polypeptide associated protein
chr19_+_45035942 0.59 ENSMUST00000237222.2
ENSMUST00000111954.11
sideroflexin 3
chr4_+_156110621 0.58 ENSMUST00000103173.10
ENSMUST00000040274.13
ENSMUST00000122001.3
tumor necrosis factor receptor superfamily, member 18
chr14_-_20844074 0.58 ENSMUST00000080440.14
ENSMUST00000100837.11
ENSMUST00000071816.7
calcium/calmodulin-dependent protein kinase II gamma
chr16_+_10298011 0.58 ENSMUST00000230450.2
class II transactivator
chr2_+_160722562 0.57 ENSMUST00000109456.9
lipin 3
chrX_+_138585728 0.57 ENSMUST00000096313.4
TBC1 domain family, member 8B
chr17_+_12803019 0.54 ENSMUST00000046959.9
ENSMUST00000233066.2
solute carrier family 22 (organic cation transporter), member 2
chr10_-_53255959 0.54 ENSMUST00000220443.2
centrosomal protein 85-like
chr2_-_119493237 0.54 ENSMUST00000028768.2
ENSMUST00000110801.8
ENSMUST00000110802.8
NADH:ubiquinone oxidoreductase complex assembly factor 1
chr10_-_128755127 0.53 ENSMUST00000149961.2
ENSMUST00000026406.14
retinol dehydrogenase 5
chr16_-_32306683 0.53 ENSMUST00000042042.9
solute carrier family 51, alpha subunit
chr3_-_108306267 0.52 ENSMUST00000147251.2
cadherin, EGF LAG seven-pass G-type receptor 2
chr5_-_86475595 0.51 ENSMUST00000122377.2
transmembrane protease, serine 11d
chr4_-_123611974 0.51 ENSMUST00000137312.2
ENSMUST00000106206.8
NADH:ubiquinone oxidoreductase core subunit S5
chr13_+_43938251 0.51 ENSMUST00000015540.4
CD83 antigen
chr7_+_43000838 0.49 ENSMUST00000206299.2
ENSMUST00000121494.2
sialic acid binding Ig-like lectin F
chr4_-_40239778 0.49 ENSMUST00000037907.13
DEAD/H box helicase 58
chr1_-_20688196 0.48 ENSMUST00000088448.12
polycystic kidney and hepatic disease 1
chr19_-_4927910 0.48 ENSMUST00000006626.5
actinin alpha 3
chr4_-_143176874 0.47 ENSMUST00000073641.4
ENSMUST00000061277.11
oogenesin 4
chr2_-_160701523 0.47 ENSMUST00000103112.8
zinc fingers and homeoboxes 3
chr19_+_45991907 0.46 ENSMUST00000099393.4
HPS6, biogenesis of lysosomal organelles complex 2 subunit 3
chr19_+_24853039 0.45 ENSMUST00000073080.7
predicted gene 10053
chr2_+_11710101 0.45 ENSMUST00000138349.8
ENSMUST00000135341.8
ENSMUST00000128156.9
interleukin 15 receptor, alpha chain
chr11_+_59433508 0.45 ENSMUST00000101148.9
NLR family, pyrin domain containing 3
chr17_-_34847013 0.44 ENSMUST00000166040.9
palmitoyl-protein thioesterase 2
chr10_+_78410180 0.44 ENSMUST00000218061.2
ENSMUST00000218787.2
ENSMUST00000105384.5
ENSMUST00000218875.2
ilvB (bacterial acetolactate synthase)-like
chr3_+_99203818 0.43 ENSMUST00000150756.3
T-box 15

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 14.6 GO:0090320 regulation of chylomicron remnant clearance(GO:0090320)
4.2 25.2 GO:0006116 NADH oxidation(GO:0006116)
1.5 1.5 GO:0090076 relaxation of skeletal muscle(GO:0090076)
1.1 3.2 GO:0031104 dendrite regeneration(GO:0031104)
0.8 2.5 GO:1903920 positive regulation of actin filament severing(GO:1903920)
0.8 3.3 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.7 2.9 GO:0033575 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.7 4.3 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.7 3.5 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.6 1.9 GO:0051542 elastin biosynthetic process(GO:0051542)
0.6 3.6 GO:0072592 oxygen metabolic process(GO:0072592)
0.6 1.8 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.6 2.9 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.5 4.7 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.5 1.9 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.4 4.5 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.4 2.2 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
0.4 1.7 GO:0030167 proteoglycan catabolic process(GO:0030167) regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.4 1.1 GO:0032618 interleukin-15 production(GO:0032618)
0.4 1.1 GO:0018931 naphthalene metabolic process(GO:0018931) naphthalene-containing compound metabolic process(GO:0090420)
0.4 1.8 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.4 3.2 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.4 1.4 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.3 2.4 GO:0007527 adult somatic muscle development(GO:0007527)
0.3 1.6 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.3 1.6 GO:0009597 detection of virus(GO:0009597)
0.3 2.8 GO:0071313 cellular response to caffeine(GO:0071313) positive regulation of the force of heart contraction(GO:0098735)
0.3 1.3 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.3 1.0 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.3 0.8 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.3 1.0 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049) nucleotide-sugar catabolic process(GO:0009227)
0.2 3.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.2 2.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.2 1.8 GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.2 0.8 GO:0042335 cuticle development(GO:0042335)
0.2 1.0 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.2 0.8 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.2 2.9 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.2 5.9 GO:0070208 protein heterotrimerization(GO:0070208)
0.2 1.5 GO:0048069 eye pigmentation(GO:0048069)
0.2 1.4 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.2 0.7 GO:0045297 mating plug formation(GO:0042628) single-organism reproductive behavior(GO:0044704) post-mating behavior(GO:0045297)
0.2 1.0 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.2 0.7 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.2 2.3 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.2 0.8 GO:0097350 neutrophil clearance(GO:0097350)
0.1 3.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 1.5 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.6 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 2.1 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.1 1.7 GO:0018158 protein oxidation(GO:0018158)
0.1 1.9 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 0.3 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1 0.3 GO:2001176 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.1 3.0 GO:0007614 short-term memory(GO:0007614)
0.1 0.2 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.7 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.1 0.3 GO:0019085 early viral transcription(GO:0019085)
0.1 1.5 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 0.6 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.1 1.6 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 1.9 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 0.4 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.1 2.0 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 0.7 GO:0042938 dipeptide transport(GO:0042938)
0.1 0.8 GO:1903208 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.1 0.3 GO:2000978 auditory receptor cell fate determination(GO:0042668) negative regulation of forebrain neuron differentiation(GO:2000978)
0.1 0.5 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.1 1.5 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.1 0.3 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.4 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.9 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 1.0 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 1.8 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 0.5 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.8 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.4 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.1 2.2 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.1 2.3 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 1.8 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.1 0.8 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.5 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.1 2.2 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.1 0.6 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 2.0 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 0.6 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.1 1.6 GO:0007413 axonal fasciculation(GO:0007413) retinal ganglion cell axon guidance(GO:0031290)
0.1 1.0 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0072695 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.0 1.7 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 1.4 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.2 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 1.9 GO:0014044 Schwann cell development(GO:0014044)
0.0 0.5 GO:0051608 histamine transport(GO:0051608)
0.0 1.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.6 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.9 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 2.1 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.0 1.7 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.5 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.6 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.4 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.6 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.4 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.9 GO:0010842 retina layer formation(GO:0010842)
0.0 0.6 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 3.2 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.7 GO:0032825 positive regulation of natural killer cell differentiation(GO:0032825)
0.0 0.3 GO:0030007 cellular potassium ion homeostasis(GO:0030007)
0.0 7.5 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.3 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.6 GO:0035357 peroxisome proliferator activated receptor signaling pathway(GO:0035357)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 1.3 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.6 GO:0009303 rRNA transcription(GO:0009303)
0.0 1.0 GO:0060325 face morphogenesis(GO:0060325)
0.0 1.9 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.8 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 1.1 GO:0048678 response to axon injury(GO:0048678)
0.0 1.1 GO:0032611 interleukin-1 beta production(GO:0032611)
0.0 0.4 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.0 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.5 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 1.0 GO:0051057 positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 0.1 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 1.1 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.7 GO:0001652 granular component(GO:0001652)
0.4 2.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.4 14.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.3 2.0 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.3 3.0 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.3 3.3 GO:0042629 mast cell granule(GO:0042629)
0.3 1.9 GO:1990584 cardiac Troponin complex(GO:1990584)
0.3 2.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.2 1.9 GO:0005579 membrane attack complex(GO:0005579)
0.2 3.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 2.9 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 2.9 GO:0045180 basal cortex(GO:0045180)
0.1 2.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.5 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.4 GO:0070722 Tle3-Aes complex(GO:0070722)
0.1 1.5 GO:0031983 vesicle lumen(GO:0031983)
0.1 2.1 GO:0031143 pseudopodium(GO:0031143)
0.1 2.4 GO:0070938 contractile ring(GO:0070938)
0.1 0.6 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.9 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.4 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 0.8 GO:0034464 BBSome(GO:0034464)
0.1 3.5 GO:0001772 immunological synapse(GO:0001772)
0.1 1.0 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 13.0 GO:0030018 Z disc(GO:0030018)
0.1 5.9 GO:0005581 collagen trimer(GO:0005581)
0.1 2.6 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 2.1 GO:0030904 retromer complex(GO:0030904)
0.0 2.9 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 6.5 GO:0042641 actomyosin(GO:0042641)
0.0 1.0 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 5.7 GO:0005604 basement membrane(GO:0005604)
0.0 1.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.6 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 2.4 GO:0014704 intercalated disc(GO:0014704)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 5.5 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.0 GO:0042588 zymogen granule(GO:0042588)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.6 GO:0005839 proteasome core complex(GO:0005839)
0.0 1.7 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 2.9 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.9 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 1.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 3.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.0 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.0 2.6 GO:0030027 lamellipodium(GO:0030027)
0.0 23.7 GO:0005739 mitochondrion(GO:0005739)
0.0 0.1 GO:0032797 SMN complex(GO:0032797)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 25.2 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
2.9 14.6 GO:0035478 chylomicron binding(GO:0035478)
0.9 2.8 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.7 2.2 GO:0016509 long-chain-enoyl-CoA hydratase activity(GO:0016508) long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.7 2.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.6 2.9 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.5 4.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.4 2.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.4 2.9 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.4 2.0 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.4 2.5 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.3 1.9 GO:0031013 troponin I binding(GO:0031013)
0.3 2.8 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.3 3.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3 1.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.3 0.8 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.3 1.0 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.2 1.4 GO:0048495 Roundabout binding(GO:0048495)
0.2 1.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 0.7 GO:0042936 dipeptide transporter activity(GO:0042936)
0.2 1.8 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.2 0.5 GO:0005333 acetylcholine transmembrane transporter activity(GO:0005277) norepinephrine transmembrane transporter activity(GO:0005333) acetate ester transmembrane transporter activity(GO:1901375)
0.2 3.4 GO:0042166 acetylcholine binding(GO:0042166)
0.2 3.3 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.2 1.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 5.5 GO:0017166 vinculin binding(GO:0017166)
0.2 0.8 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.2 2.7 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.2 0.8 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.2 0.6 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.8 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 2.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.7 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 3.3 GO:0031005 filamin binding(GO:0031005)
0.1 0.8 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 3.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 6.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 2.1 GO:0010181 FMN binding(GO:0010181)
0.1 2.9 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.2 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 1.5 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 0.8 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.3 GO:0071820 N-box binding(GO:0071820)
0.1 0.6 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.1 0.6 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.4 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 0.3 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 1.4 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.7 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.7 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.6 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 1.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 1.0 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.8 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 1.7 GO:0019956 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950) chemokine binding(GO:0019956)
0.0 1.8 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.7 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 1.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 2.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.3 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.4 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.1 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.0 1.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.4 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 3.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 7.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 1.2 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 1.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 7.0 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 1.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.8 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 1.0 GO:0043022 ribosome binding(GO:0043022)
0.0 0.3 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 2.6 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.5 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 2.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 10.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 2.3 PID RAS PATHWAY Regulation of Ras family activation
0.0 2.3 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 8.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 9.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 2.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 2.2 PID AP1 PATHWAY AP-1 transcription factor network
0.0 2.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 2.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.7 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.7 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 2.0 PID CDC42 PATHWAY CDC42 signaling events
0.0 1.0 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 1.7 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 2.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.2 7.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 3.0 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2 2.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 2.8 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 3.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 2.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.6 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 3.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.9 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.9 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.6 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 2.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 2.7 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 2.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 2.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.0 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 1.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 1.1 REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0 0.4 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 1.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.7 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters