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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Nkx6-2

Z-value: 0.98

Motif logo

Transcription factors associated with Nkx6-2

Gene Symbol Gene ID Gene Info
ENSMUSG00000041309.18 Nkx6-2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nkx6-2mm39_v1_chr7_-_139162706_1391627240.235.3e-02Click!

Activity profile of Nkx6-2 motif

Sorted Z-values of Nkx6-2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx6-2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr8_-_62576140 11.36 ENSMUST00000034052.14
ENSMUST00000034054.9
annexin A10
chr3_+_138019040 7.85 ENSMUST00000013455.13
ENSMUST00000106247.2
alcohol dehydrogenase 6A (class V)
chr3_+_106020545 7.46 ENSMUST00000079132.12
ENSMUST00000139086.2
chitinase, acidic 1
chr3_+_69129745 6.99 ENSMUST00000183126.2
ADP-ribosylation factor-like 14
chr10_+_115653152 6.76 ENSMUST00000080630.11
ENSMUST00000179196.3
ENSMUST00000035563.15
tetraspanin 8
chr8_-_65582206 5.55 ENSMUST00000098713.5
small integral membrane protein 31
chr19_+_58717319 5.54 ENSMUST00000048644.6
ENSMUST00000236445.2
pancreatic lipase related protein 1
chr16_+_96268806 4.92 ENSMUST00000061739.9
Purkinje cell protein 4
chr5_+_66833434 4.73 ENSMUST00000031131.11
ubiquitin carboxy-terminal hydrolase L1
chr8_-_65146079 4.67 ENSMUST00000048967.9
carboxypeptidase E
chr5_+_92957231 3.86 ENSMUST00000113054.9
shroom family member 3
chr8_+_21515561 3.74 ENSMUST00000076754.3
defensin, alpha, 21
chr5_-_87682972 3.60 ENSMUST00000120150.2
sulfotransferase family 1B, member 1
chr5_+_92831150 3.60 ENSMUST00000113055.9
shroom family member 3
chr14_+_80237691 3.57 ENSMUST00000228749.2
ENSMUST00000088735.4
olfactomedin 4
chr8_+_21652293 3.56 ENSMUST00000098897.2
defensin, alpha, 22
chr2_-_103114105 3.55 ENSMUST00000111174.8
ets homologous factor
chr5_+_92831468 3.52 ENSMUST00000168878.8
shroom family member 3
chr8_+_22055402 3.46 ENSMUST00000084040.3
defensin, alpha, 37
chr9_-_123507847 3.36 ENSMUST00000170591.2
ENSMUST00000171647.9
solute carrier family 6 (neurotransmitter transporter), member 20A
chr8_+_21917427 3.35 ENSMUST00000095424.6
defensin, alpha, 36
chrX_+_138464065 3.23 ENSMUST00000113027.8
ring finger protein 128
chr8_+_21787455 3.16 ENSMUST00000098892.5
defensin, alpha, 5
chr13_+_31740117 3.07 ENSMUST00000042118.11
forkhead box Q1
chr8_+_22155813 2.99 ENSMUST00000075268.5
defensin, alpha, 34
chr8_+_94537910 2.92 ENSMUST00000138659.9
guanine nucleotide binding protein, alpha O
chr2_+_24043159 2.83 ENSMUST00000028363.2
interleukin 1 family, member 8
chr9_-_21223631 2.48 ENSMUST00000115433.11
adaptor protein complex AP-1, mu 2 subunit
chr16_-_21980200 2.40 ENSMUST00000115379.2
insulin-like growth factor 2 mRNA binding protein 2
chr2_+_125876883 2.31 ENSMUST00000110442.2
fibroblast growth factor 7
chr2_+_83642910 2.22 ENSMUST00000051454.4
family with sequence similarity 171, member B
chr5_+_75312939 2.14 ENSMUST00000202681.4
ENSMUST00000000476.15
platelet derived growth factor receptor, alpha polypeptide
chr2_+_22512195 2.02 ENSMUST00000028123.4
glutamic acid decarboxylase 2
chr17_-_43003135 1.93 ENSMUST00000170723.8
ENSMUST00000164524.2
ENSMUST00000024711.11
ENSMUST00000167993.8
adhesion G protein-coupled receptor F4
chr18_+_34973605 1.90 ENSMUST00000043484.8
receptor accessory protein 2
chr1_+_66360865 1.90 ENSMUST00000114013.8
microtubule-associated protein 2
chr1_+_177557380 1.80 ENSMUST00000016106.6
RIKEN cDNA 1700016C15 gene
chr18_-_43032359 1.78 ENSMUST00000117687.8
protein phosphatase 2, regulatory subunit B, beta
chr5_-_66211842 1.76 ENSMUST00000200852.4
RNA binding motif protein 47
chr4_-_154721288 1.76 ENSMUST00000030902.13
ENSMUST00000105637.8
ENSMUST00000070313.14
ENSMUST00000105636.8
ENSMUST00000105638.9
ENSMUST00000097759.9
ENSMUST00000124771.2
PR domain containing 16
chr2_+_125876566 1.62 ENSMUST00000064794.14
fibroblast growth factor 7
chr1_+_170136372 1.57 ENSMUST00000056991.6
spermatogenesis associated 46
chr5_-_51711237 1.55 ENSMUST00000132734.8
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr5_-_131336914 1.54 ENSMUST00000160609.2
polypeptide N-acetylgalactosaminyltransferase 17
chr3_+_96508400 1.53 ENSMUST00000062058.5
Lix1-like
chr7_-_44711771 1.45 ENSMUST00000210101.2
ENSMUST00000209219.2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr11_+_100902572 1.41 ENSMUST00000092663.4
ATPase, H+ transporting, lysosomal V0 subunit A1
chr7_+_43339842 1.40 ENSMUST00000056329.7
kallikrein related-peptidase 14
chr2_-_32976378 1.40 ENSMUST00000049618.9
GTPase activating RANGAP domain-like 3
chr5_-_51711204 1.39 ENSMUST00000196968.5
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr1_-_149836974 1.38 ENSMUST00000190507.2
ENSMUST00000070200.15
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr18_-_79152504 1.37 ENSMUST00000025430.11
SET binding protein 1
chr2_-_84481058 1.37 ENSMUST00000111670.9
ENSMUST00000111697.9
ENSMUST00000111696.8
ENSMUST00000111678.8
ENSMUST00000111690.8
ENSMUST00000111695.8
ENSMUST00000111677.8
ENSMUST00000111698.8
ENSMUST00000099941.9
ENSMUST00000111676.8
ENSMUST00000111694.8
ENSMUST00000111675.8
ENSMUST00000111689.8
ENSMUST00000111687.8
ENSMUST00000111692.8
ENSMUST00000111685.8
ENSMUST00000111686.8
ENSMUST00000111688.8
ENSMUST00000111693.8
ENSMUST00000111684.8
catenin (cadherin associated protein), delta 1
chr1_+_34044940 1.36 ENSMUST00000187486.7
ENSMUST00000182697.8
dystonin
chr16_+_45355654 1.35 ENSMUST00000159945.8
solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1
chr9_-_35469818 1.34 ENSMUST00000034612.7
DEAD box helicase 25
chr1_+_43484895 1.30 ENSMUST00000086421.9
non-catalytic region of tyrosine kinase adaptor protein 2
chr12_-_80807454 1.27 ENSMUST00000073251.8
coiled-coil domain containing 177
chr18_+_37568647 1.26 ENSMUST00000055495.6
protocadherin beta 12
chr3_+_55369149 1.24 ENSMUST00000199585.5
ENSMUST00000070418.9
doublecortin-like kinase 1
chr11_-_101062111 1.24 ENSMUST00000164474.8
ENSMUST00000043397.14
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr6_+_40619913 1.18 ENSMUST00000238599.2
maltase-glucoamylase
chr2_+_157209506 1.17 ENSMUST00000081202.6
mannosidase, beta A, lysosomal-like
chr3_+_85946145 1.17 ENSMUST00000238331.2
SH3 domain protein D19
chr3_+_103482591 1.15 ENSMUST00000090697.11
ENSMUST00000239027.2
synaptotagmin VI
chr6_-_102441628 1.12 ENSMUST00000032159.7
contactin 3
chr15_+_18819033 1.12 ENSMUST00000166873.9
cadherin 10
chr15_-_13173736 1.11 ENSMUST00000036439.6
cadherin 6
chr2_-_32977182 1.09 ENSMUST00000102810.10
GTPase activating RANGAP domain-like 3
chr5_-_87739442 1.07 ENSMUST00000031201.9
sulfotransferase family 1E, member 1
chr18_-_43032514 1.03 ENSMUST00000236238.2
protein phosphatase 2, regulatory subunit B, beta
chr12_+_117807607 0.98 ENSMUST00000176735.8
ENSMUST00000177339.2
cell division cycle associated 7 like
chr7_+_4925781 0.98 ENSMUST00000207527.2
ENSMUST00000207687.2
ENSMUST00000208754.2
N-acetyltransferase 14
chr11_+_104983022 0.97 ENSMUST00000021029.6
EF-hand calcium binding domain 3
chr4_-_106588122 0.93 ENSMUST00000148281.2
maestro heat-like repeat family member 7
chr4_-_117039809 0.93 ENSMUST00000065896.9
kinesin family member 2C
chr6_-_57367651 0.92 ENSMUST00000164732.2
vomeronasal 1 receptor 18
chr2_-_84481020 0.90 ENSMUST00000067232.10
catenin (cadherin associated protein), delta 1
chr1_+_66361252 0.89 ENSMUST00000123647.8
microtubule-associated protein 2
chr8_-_62355690 0.87 ENSMUST00000121785.9
ENSMUST00000034057.14
palladin, cytoskeletal associated protein
chr16_-_44153288 0.85 ENSMUST00000136381.8
SID1 transmembrane family, member 1
chr6_-_66656668 0.84 ENSMUST00000071414.2
vomeronasal 1 receptor 35
chr4_-_83203388 0.84 ENSMUST00000150522.8
tetratricopeptide repeat domain 39B
chr10_+_18283405 0.83 ENSMUST00000037341.14
NHS-like 1
chr2_-_84481101 0.81 ENSMUST00000111691.2
catenin (cadherin associated protein), delta 1
chr5_+_148239975 0.81 ENSMUST00000152105.8
ENSMUST00000085554.5
microtubule associated tumor suppressor candidate 2
chr6_-_124746468 0.80 ENSMUST00000204896.3
enolase 2, gamma neuronal
chr2_+_85715984 0.77 ENSMUST00000213441.3
olfactory receptor 1023
chr6_-_13839914 0.76 ENSMUST00000060442.14
G protein-coupled receptor 85
chr14_+_27598021 0.76 ENSMUST00000211684.2
ENSMUST00000210924.2
ELKS/RAB6-interacting/CAST family member 2
chr4_+_145595364 0.76 ENSMUST00000123460.2
zinc finger protein 986
chr4_+_3940747 0.72 ENSMUST00000119403.2
coiled-coil-helix-coiled-coil-helix domain containing 7
chr2_-_84480804 0.71 ENSMUST00000066177.10
catenin (cadherin associated protein), delta 1
chr4_-_138641225 0.70 ENSMUST00000097830.4
OTU domain containing 3
chr4_-_97472844 0.67 ENSMUST00000107067.8
ENSMUST00000107068.9
RIKEN cDNA E130114P18 gene
chr4_+_147106307 0.67 ENSMUST00000075775.6
reduced expression 2
chr15_-_79718423 0.67 ENSMUST00000109623.8
ENSMUST00000109625.8
ENSMUST00000023060.13
ENSMUST00000089299.6
chromobox 6
neuronal pentraxin chromo domain
chr11_+_98754434 0.66 ENSMUST00000142414.8
ENSMUST00000037480.9
WAS/WASL interacting protein family, member 2
chr19_+_32597379 0.66 ENSMUST00000236290.2
ENSMUST00000025833.7
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr11_-_73215442 0.66 ENSMUST00000021119.9
aspartoacylase
chr4_-_91264670 0.66 ENSMUST00000107109.9
ENSMUST00000107111.9
ENSMUST00000107120.8
ELAV like RNA binding protein 1
chr10_+_26698556 0.64 ENSMUST00000135866.2
Rho GTPase activating protein 18
chr7_-_142215027 0.64 ENSMUST00000105936.8
insulin-like growth factor 2
chr17_-_48739874 0.64 ENSMUST00000046549.5
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr2_-_164493683 0.62 ENSMUST00000099095.4
WAP four-disulfide core domain 9
chr10_-_102866076 0.62 ENSMUST00000218282.2
ENSMUST00000170026.2
ALX homeobox 1
predicted gene 17028
chr16_-_44153498 0.61 ENSMUST00000047446.13
SID1 transmembrane family, member 1
chr4_-_146993984 0.60 ENSMUST00000238583.2
ENSMUST00000049821.4
predicted gene, 21411
chr4_+_146586445 0.60 ENSMUST00000105735.9
zinc finger protein 981
chr3_-_96359622 0.59 ENSMUST00000093126.11
ENSMUST00000098841.4
cDNA sequence BC107364
chr11_+_62770275 0.57 ENSMUST00000014321.5
trans-golgi network vesicle protein 23B
chr4_+_147390131 0.57 ENSMUST00000148762.4
zinc finger protein 988
chr4_+_145241454 0.55 ENSMUST00000105741.2
zinc finger protein 990
chr4_+_90107057 0.52 ENSMUST00000107129.2
zinc finger protein 352
chr19_+_13208692 0.52 ENSMUST00000207246.4
olfactory receptor 1463
chr1_+_63215976 0.51 ENSMUST00000129339.8
eukaryotic translation elongation factor 1 beta 2
chr19_-_33728759 0.51 ENSMUST00000147153.4
lipase, member O2
chr19_-_14575395 0.51 ENSMUST00000052011.15
ENSMUST00000167776.3
transducin-like enhancer of split 4
chr5_-_86780277 0.51 ENSMUST00000116553.9
transmembrane protease, serine 11f
chr7_-_85985625 0.50 ENSMUST00000069279.5
olfactory receptor 307
chr4_+_146033882 0.50 ENSMUST00000105730.2
ENSMUST00000091878.6
zinc finger protein 987
chr4_+_146093394 0.50 ENSMUST00000168483.9
zinc finger protein 600
chr1_-_63215812 0.49 ENSMUST00000185847.2
ENSMUST00000185732.7
ENSMUST00000188370.7
ENSMUST00000168099.9
NADH:ubiquinone oxidoreductase core subunit S1
chr15_+_39255185 0.48 ENSMUST00000228839.2
regulating synaptic membrane exocytosis 2
chr4_-_147787010 0.46 ENSMUST00000117638.2
zinc finger protein 534
chr8_-_49008305 0.46 ENSMUST00000110346.9
ENSMUST00000211976.2
teneurin transmembrane protein 3
chr2_+_3115250 0.46 ENSMUST00000072955.12
family with sequence similarity 171, member A1
chr4_+_145237329 0.44 ENSMUST00000105742.8
ENSMUST00000136309.8
zinc finger protein 990
chrX_+_151922936 0.43 ENSMUST00000039720.11
ENSMUST00000144175.3
Ras-related GTP binding B
chr4_+_147445744 0.42 ENSMUST00000133078.8
ENSMUST00000154154.2
zinc finger protein 978
chr10_+_79746690 0.42 ENSMUST00000181321.2
predicted gene, 26602
chr6_+_132739094 0.40 ENSMUST00000069268.3
taste receptor, type 2, member 102
chr4_+_140428777 0.40 ENSMUST00000138808.8
ENSMUST00000038893.6
regulator of chromosome condensation 2
chr5_+_110987839 0.39 ENSMUST00000200172.2
ENSMUST00000066160.3
checkpoint kinase 2
chr1_+_63216281 0.39 ENSMUST00000188524.2
eukaryotic translation elongation factor 1 beta 2
chr17_-_30107544 0.38 ENSMUST00000171691.9
MAM domain containing glycosylphosphatidylinositol anchor 1
chr7_+_3648264 0.37 ENSMUST00000206287.2
ENSMUST00000038913.16
CCR4-NOT transcription complex, subunit 3
chr6_-_119940694 0.36 ENSMUST00000161512.3
WNK lysine deficient protein kinase 1
chr11_-_101857831 0.36 ENSMUST00000001534.7
sclerostin
chr3_-_75072319 0.35 ENSMUST00000124618.2
zinc finger, B-box domain containing
chr11_-_4391082 0.33 ENSMUST00000109949.8
ENSMUST00000130174.2
HORMA domain containing 2
chr1_-_63215952 0.33 ENSMUST00000185412.7
ENSMUST00000027111.15
ENSMUST00000189664.2
NADH:ubiquinone oxidoreductase core subunit S1
chr3_+_103482547 0.32 ENSMUST00000121834.8
synaptotagmin VI
chr7_-_102805563 0.32 ENSMUST00000218483.2
olfactory receptor 589
chr2_-_89675315 0.31 ENSMUST00000099762.2
olfactory receptor 48
chr16_+_48877762 0.31 ENSMUST00000168680.2
myosin, heavy chain 15
chr5_-_110987604 0.30 ENSMUST00000056937.12
HscB iron-sulfur cluster co-chaperone
chr15_+_34453432 0.29 ENSMUST00000060894.9
glutamate rich 5
chr8_-_22396428 0.29 ENSMUST00000051965.5
defensin beta 11
chrX_-_111315519 0.29 ENSMUST00000124335.8
spermidine/spermine N1-acetyl transferase-like 1
chr11_+_52251687 0.29 ENSMUST00000102758.8
voltage-dependent anion channel 1
chr2_+_163535925 0.28 ENSMUST00000109400.3
protein kinase inhibitor, gamma
chr18_-_84104507 0.28 ENSMUST00000060303.10
teashirt zinc finger family member 1
chr14_+_65504067 0.27 ENSMUST00000224629.2
F-box protein 16
chr18_+_57275854 0.27 ENSMUST00000139892.2
multiple EGF-like-domains 10
chr8_+_41128099 0.27 ENSMUST00000051614.5
a disintegrin and metallopeptidase domain 24 (testase 1)
chrX_+_109857866 0.27 ENSMUST00000078229.5
POU domain, class 3, transcription factor 4
chr7_-_10009278 0.26 ENSMUST00000060374.5
vomeronasal 1 receptor 66
chr3_+_68479578 0.26 ENSMUST00000170788.9
schwannomin interacting protein 1
chr7_+_107679062 0.25 ENSMUST00000213601.2
olfactory receptor 481
chr2_+_85838122 0.24 ENSMUST00000062166.2
olfactory receptor 1032
chr2_+_87609827 0.24 ENSMUST00000105210.3
olfactory receptor 152
chr4_-_43823866 0.24 ENSMUST00000215406.2
ENSMUST00000079234.6
ENSMUST00000214843.2
olfactory receptor 156
chr18_+_4993795 0.24 ENSMUST00000153016.8
supervillin
chr3_+_5815863 0.24 ENSMUST00000192045.2
predicted pseudogene 8797
chr7_-_19449319 0.24 ENSMUST00000032555.10
ENSMUST00000093552.12
translocase of outer mitochondrial membrane 40
chr5_-_110987441 0.23 ENSMUST00000145318.2
HscB iron-sulfur cluster co-chaperone
chr18_+_37554471 0.23 ENSMUST00000053073.6
protocadherin beta 11
chr16_-_59166089 0.22 ENSMUST00000084791.4
olfactory receptor 206
chr2_+_85600147 0.22 ENSMUST00000065626.3
olfactory receptor 1013
chr15_-_84804239 0.22 ENSMUST00000189185.2
predicted gene 29666
chr11_-_73382303 0.21 ENSMUST00000119863.2
ENSMUST00000215358.2
ENSMUST00000214623.2
olfactory receptor 381
chr2_-_69619864 0.20 ENSMUST00000094942.4
coiled-coil domain containing 173
chr2_-_87467879 0.20 ENSMUST00000216082.2
olfactory receptor 1132
chr15_+_98335351 0.19 ENSMUST00000075851.4
olfactory receptor 282
chr2_+_109522781 0.19 ENSMUST00000111050.10
brain derived neurotrophic factor
chr6_+_125026865 0.19 ENSMUST00000112413.8
proacrosin binding protein
chr9_-_113537277 0.18 ENSMUST00000111861.4
ENSMUST00000035086.13
programmed cell death 6 interacting protein
chr13_+_41302272 0.18 ENSMUST00000141292.9
synaptonemal complex protein 2-like
chr1_+_88062508 0.18 ENSMUST00000113134.8
ENSMUST00000140092.8
UDP glucuronosyltransferase 1 family, polypeptide A6A
chrX_-_36485911 0.17 ENSMUST00000115210.2
reproductive homeobox 1
chr4_+_145397238 0.17 ENSMUST00000105738.9
zinc finger protein 980
chr2_-_89671899 0.16 ENSMUST00000213833.2
olfactory receptor 1256
chr14_-_32110312 0.15 ENSMUST00000100723.4
RIKEN cDNA 1700024G13 gene
chr4_-_147726953 0.14 ENSMUST00000133006.2
ENSMUST00000037565.14
ENSMUST00000105720.8
zinc finger protein 979
chr6_-_81942906 0.14 ENSMUST00000032124.9
mitochondrial ribosomal protein L19
chr7_-_5325456 0.14 ENSMUST00000207520.2
NLR family, pyrin domain containing 2
chr5_+_140404997 0.14 ENSMUST00000100507.8
eukaryotic translation initiation factor 3, subunit B
chr2_-_37537224 0.13 ENSMUST00000028279.10
spermatid perinuclear RNA binding protein
chr18_-_84104574 0.13 ENSMUST00000175783.3
teashirt zinc finger family member 1
chr4_+_147056433 0.13 ENSMUST00000146688.3
zinc finger protein 989
chr16_+_44215136 0.12 ENSMUST00000099742.9
cilia and flagella associated protein 44
chr7_-_102998876 0.12 ENSMUST00000215042.2
olfactory receptor 600
chr6_-_66614736 0.10 ENSMUST00000074381.6
vomeronasal 1 receptor 34
chr11_-_4390745 0.09 ENSMUST00000109948.8
HORMA domain containing 2
chr9_+_91250864 0.09 ENSMUST00000173054.8
zinc finger protein of the cerebellum 4
chr7_-_142215595 0.09 ENSMUST00000145896.3
insulin-like growth factor 2
chr19_-_13827773 0.09 ENSMUST00000215350.2
olfactory receptor 1501
chr11_-_115824290 0.09 ENSMUST00000021097.10
RecQ protein-like 5
chr5_+_20112704 0.09 ENSMUST00000115267.7
membrane associated guanylate kinase, WW and PDZ domain containing 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:0030070 insulin processing(GO:0030070)
1.3 3.9 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
1.0 2.9 GO:1904635 glomerular visceral epithelial cell apoptotic process(GO:1903210) regulation of glomerular visceral epithelial cell apoptotic process(GO:1904633) positive regulation of glomerular visceral epithelial cell apoptotic process(GO:1904635) positive regulation of progesterone biosynthetic process(GO:2000184)
0.8 3.4 GO:0035524 proline transmembrane transport(GO:0035524)
0.8 7.5 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.8 4.9 GO:0007412 axon target recognition(GO:0007412)
0.8 4.7 GO:0006068 ethanol catabolic process(GO:0006068)
0.6 3.8 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.5 2.1 GO:0072277 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.4 2.0 GO:0006538 glutamate catabolic process(GO:0006538)
0.3 1.9 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.3 4.9 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.3 1.3 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.2 1.5 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.2 0.7 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.2 1.4 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.2 2.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 0.7 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.2 2.8 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.2 0.9 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 1.5 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.4 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.1 1.8 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 1.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.7 GO:0006083 acetate metabolic process(GO:0006083)
0.1 1.4 GO:0007320 insemination(GO:0007320)
0.1 11.0 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.1 6.8 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 1.4 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 1.6 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 0.8 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.4 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.1 0.4 GO:0060023 soft palate development(GO:0060023)
0.1 0.5 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 1.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.7 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 0.4 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1 2.6 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.1 0.3 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.3 GO:0060468 prevention of polyspermy(GO:0060468)
0.1 2.8 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 3.6 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 1.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.4 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.2 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 2.9 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.9 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.4 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 1.5 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.5 GO:0098828 spontaneous neurotransmitter secretion(GO:0061669) positive regulation of inhibitory postsynaptic potential(GO:0097151) spontaneous synaptic transmission(GO:0098814) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:0022601 menstrual cycle phase(GO:0022601)
0.0 0.3 GO:0043652 engulfment of apoptotic cell(GO:0043652) recognition of apoptotic cell(GO:0043654)
0.0 0.4 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.0 2.8 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 1.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 1.2 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.5 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.1 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 7.6 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.3 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 2.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.2 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.9 GO:0006414 translational elongation(GO:0006414)
0.0 2.0 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.6 GO:0001755 neural crest cell migration(GO:0001755)
0.0 0.3 GO:0008210 estrogen metabolic process(GO:0008210)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:1990843 subsarcolemmal mitochondrion(GO:1990843) interfibrillar mitochondrion(GO:1990844)
0.4 4.9 GO:0005883 neurofilament(GO:0005883)
0.3 2.8 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.3 3.8 GO:0005915 zonula adherens(GO:0005915)
0.2 4.7 GO:0031045 dense core granule(GO:0031045)
0.2 1.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2 1.4 GO:0031673 H zone(GO:0031673)
0.1 3.6 GO:0042581 specific granule(GO:0042581)
0.1 0.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.4 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 1.3 GO:0033391 chromatoid body(GO:0033391)
0.1 0.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 2.5 GO:0060077 inhibitory synapse(GO:0060077)
0.1 1.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 9.9 GO:0043296 apical junction complex(GO:0043296)
0.0 1.4 GO:0042588 zymogen granule(GO:0042588)
0.0 0.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 1.8 GO:0016235 aggresome(GO:0016235)
0.0 0.9 GO:0035371 microtubule plus-end(GO:0035371)
0.0 2.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 2.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.9 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.5 GO:0046930 pore complex(GO:0046930)
0.0 5.7 GO:0044306 neuron projection terminus(GO:0044306)
0.0 0.9 GO:0002102 podosome(GO:0002102) axonal growth cone(GO:0044295)
0.0 3.2 GO:0005770 late endosome(GO:0005770)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.0 GO:1990716 axonemal central apparatus(GO:1990716)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.7 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.8 7.5 GO:0004568 chitinase activity(GO:0004568)
0.7 3.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.7 2.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.6 3.9 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.4 4.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.4 2.9 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.3 3.4 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.3 2.8 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.3 2.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.3 5.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.2 1.5 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.2 0.7 GO:0019807 aspartoacylase activity(GO:0019807)
0.2 1.2 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.2 14.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 0.7 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.2 1.1 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.1 1.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 2.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 2.9 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 2.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.3 GO:0019809 spermidine binding(GO:0019809)
0.1 0.6 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.2 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 0.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.5 GO:0015288 porin activity(GO:0015288)
0.0 1.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0032090 Pyrin domain binding(GO:0032090)
0.0 1.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 10.8 GO:0051015 actin filament binding(GO:0051015)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 2.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 5.2 GO:0005178 integrin binding(GO:0005178)
0.0 1.2 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.4 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.7 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 1.3 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 2.0 GO:0005550 pheromone binding(GO:0005550)
0.0 3.9 GO:0005516 calmodulin binding(GO:0005516)
0.0 3.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 5.8 GO:0005525 GTP binding(GO:0005525)
0.0 0.5 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 8.5 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 4.7 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 2.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 2.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 2.8 PID ATR PATHWAY ATR signaling pathway
0.0 3.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 7.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.8 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.4 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.9 PID AURORA B PATHWAY Aurora B signaling
0.0 3.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 1.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 3.2 REACTOME DEFENSINS Genes involved in Defensins
0.2 4.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.2 6.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 2.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 3.9 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 2.0 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 2.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 2.9 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.9 REACTOME KINESINS Genes involved in Kinesins
0.0 2.4 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 1.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport