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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Nr0b1

Z-value: 0.56

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Transcription factors associated with Nr0b1

Gene Symbol Gene ID Gene Info
Nr0b1
ENSMUSG00000025056.5 Nr0b1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr0b1mm39_v1_chrX_+_85235370_852353880.132.7e-01Click!

Activity profile of Nr0b1 motif

Sorted Z-values of Nr0b1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr0b1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_+_88015524 4.44 ENSMUST00000113139.2
Ugt1a8
UDP glucuronosyltransferase 1 family, polypeptide A8
chr9_-_119812042 2.48 ENSMUST00000214058.2
Csrnp1
cysteine-serine-rich nuclear protein 1
chr5_-_107873883 2.48 ENSMUST00000159263.3
Gfi1
growth factor independent 1 transcription repressor
chr9_-_110571645 2.47 ENSMUST00000006005.12
Pth1r
parathyroid hormone 1 receptor
chr2_+_27567213 2.05 ENSMUST00000077257.12
Rxra
retinoid X receptor alpha
chr2_+_4722956 2.05 ENSMUST00000056914.7
Bend7
BEN domain containing 7
chr11_-_69260203 1.86 ENSMUST00000092971.13
ENSMUST00000108661.8
Chd3
chromodomain helicase DNA binding protein 3
chr5_+_3393893 1.72 ENSMUST00000165117.8
ENSMUST00000197385.2
Cdk6
cyclin-dependent kinase 6
chr11_-_115503704 1.66 ENSMUST00000106506.8
Mif4gd
MIF4G domain containing
chr18_+_35963353 1.63 ENSMUST00000235169.2
Cxxc5
CXXC finger 5
chr6_-_72212547 1.59 ENSMUST00000042646.8
Atoh8
atonal bHLH transcription factor 8
chr4_+_148215339 1.54 ENSMUST00000084129.9
Mad2l2
MAD2 mitotic arrest deficient-like 2
chr8_-_71834543 1.53 ENSMUST00000002466.9
Nr2f6
nuclear receptor subfamily 2, group F, member 6
chr11_-_52165682 1.51 ENSMUST00000238914.2
Tcf7
transcription factor 7, T cell specific
chr12_-_104831335 1.47 ENSMUST00000109936.3
Clmn
calmin
chr2_-_144174066 1.45 ENSMUST00000037423.4
Ovol2
ovo like zinc finger 2
chr10_-_127504416 1.45 ENSMUST00000129252.2
Nab2
Ngfi-A binding protein 2
chr3_+_86131970 1.42 ENSMUST00000192145.6
ENSMUST00000194759.6
ENSMUST00000107635.7
Lrba
LPS-responsive beige-like anchor
chr2_-_157121440 1.40 ENSMUST00000143663.2
Mroh8
maestro heat-like repeat family member 8
chr13_+_44884200 1.30 ENSMUST00000173704.8
ENSMUST00000044608.14
ENSMUST00000173367.8
Jarid2
jumonji, AT rich interactive domain 2
chr11_-_88608958 1.29 ENSMUST00000107908.2
Msi2
musashi RNA-binding protein 2
chr4_-_123644091 1.26 ENSMUST00000102636.4
Akirin1
akirin 1
chr6_+_120643323 1.25 ENSMUST00000112686.8
Cecr2
CECR2, histone acetyl-lysine reader
chr15_-_85918378 1.24 ENSMUST00000016172.10
Celsr1
cadherin, EGF LAG seven-pass G-type receptor 1
chr17_-_23964807 1.24 ENSMUST00000046525.10
Kremen2
kringle containing transmembrane protein 2
chr5_+_31070739 1.24 ENSMUST00000031055.8
Emilin1
elastin microfibril interfacer 1
chr11_-_115503316 1.18 ENSMUST00000106507.9
Mif4gd
MIF4G domain containing
chr11_-_88609048 1.13 ENSMUST00000107909.8
Msi2
musashi RNA-binding protein 2
chr19_-_24533183 1.11 ENSMUST00000112673.9
ENSMUST00000025800.15
Pip5k1b
phosphatidylinositol-4-phosphate 5-kinase, type 1 beta
chr10_-_128425519 1.10 ENSMUST00000082059.7
Erbb3
erb-b2 receptor tyrosine kinase 3
chr2_-_144173615 1.10 ENSMUST00000103171.10
Ovol2
ovo like zinc finger 2
chr19_+_37423198 1.05 ENSMUST00000025944.9
Hhex
hematopoietically expressed homeobox
chr13_+_94495457 1.01 ENSMUST00000022196.5
Ap3b1
adaptor-related protein complex 3, beta 1 subunit
chr2_+_153684901 0.95 ENSMUST00000175856.3
Efcab8
EF-hand calcium binding domain 8
chr11_+_107438751 0.93 ENSMUST00000100305.8
ENSMUST00000075012.8
ENSMUST00000106746.8
Helz
helicase with zinc finger domain
chr10_+_36383008 0.93 ENSMUST00000168572.8
Hs3st5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr11_-_69871320 0.90 ENSMUST00000143175.2
Elp5
elongator acetyltransferase complex subunit 5
chr4_-_129590609 0.90 ENSMUST00000102588.10
Tmem39b
transmembrane protein 39b
chr6_+_134012916 0.87 ENSMUST00000164648.2
Etv6
ets variant 6
chrX_-_37653396 0.85 ENSMUST00000016681.15
Cul4b
cullin 4B
chr2_+_157120946 0.84 ENSMUST00000116380.9
ENSMUST00000029171.6
Rpn2
ribophorin II
chrX_+_13147209 0.83 ENSMUST00000000804.7
Ddx3x
DEAD box helicase 3, X-linked
chr10_-_81186137 0.81 ENSMUST00000167481.8
Hmg20b
high mobility group 20B
chr10_-_81186025 0.74 ENSMUST00000122993.8
Hmg20b
high mobility group 20B
chr7_+_79675727 0.73 ENSMUST00000049680.10
Zfp710
zinc finger protein 710
chr10_-_81186222 0.71 ENSMUST00000020454.11
ENSMUST00000105324.9
ENSMUST00000154609.3
ENSMUST00000105323.8
Hmg20b
high mobility group 20B
chr8_-_106434565 0.69 ENSMUST00000013299.11
Enkd1
enkurin domain containing 1
chr11_+_85723377 0.67 ENSMUST00000000095.7
Tbx2
T-box 2
chr18_+_7869066 0.67 ENSMUST00000171486.8
ENSMUST00000170932.8
ENSMUST00000167020.8
Wac
WW domain containing adaptor with coiled-coil
chr6_+_85164420 0.67 ENSMUST00000045942.9
Emx1
empty spiracles homeobox 1
chr17_+_23898223 0.65 ENSMUST00000024699.4
ENSMUST00000232719.2
Cldn6
claudin 6
chr2_-_131194754 0.52 ENSMUST00000059372.11
Rnf24
ring finger protein 24
chr11_+_105072619 0.52 ENSMUST00000092537.10
ENSMUST00000015107.13
ENSMUST00000145048.8
Tlk2
tousled-like kinase 2 (Arabidopsis)
chr7_-_133826817 0.42 ENSMUST00000067680.11
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr11_+_3152874 0.42 ENSMUST00000179770.8
ENSMUST00000110048.8
Eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr11_-_62348115 0.41 ENSMUST00000069456.11
ENSMUST00000018645.13
Ncor1
nuclear receptor co-repressor 1
chr8_+_106434901 0.39 ENSMUST00000013302.7
ENSMUST00000211852.2
4933405L10Rik
RIKEN cDNA 4933405L10 gene
chr5_-_137530214 0.38 ENSMUST00000140139.2
Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr2_+_129040677 0.37 ENSMUST00000028880.10
Slc20a1
solute carrier family 20, member 1
chr7_-_30560989 0.35 ENSMUST00000052700.6
Ffar1
free fatty acid receptor 1
chr17_+_88837540 0.34 ENSMUST00000038551.8
Ppp1r21
protein phosphatase 1, regulatory subunit 21
chr5_-_108134869 0.31 ENSMUST00000145239.2
ENSMUST00000031198.11
Dipk1a
divergent protein kinase domain 1A
chrX_-_47123719 0.24 ENSMUST00000039026.8
Apln
apelin
chr6_+_83771985 0.21 ENSMUST00000113851.8
Nagk
N-acetylglucosamine kinase
chr18_+_7868823 0.17 ENSMUST00000171042.8
ENSMUST00000166378.8
ENSMUST00000074919.11
Wac
WW domain containing adaptor with coiled-coil
chr4_-_148215135 0.16 ENSMUST00000030862.5
Draxin
dorsal inhibitory axon guidance protein
chr11_-_62348599 0.14 ENSMUST00000127471.9
Ncor1
nuclear receptor co-repressor 1
chr2_-_52314837 0.10 ENSMUST00000036541.8
Arl5a
ADP-ribosylation factor-like 5A
chr8_-_85807308 0.10 ENSMUST00000093357.12
Wdr83
WD repeat domain containing 83
chr5_-_31350449 0.09 ENSMUST00000166769.8
Eif2b4
eukaryotic translation initiation factor 2B, subunit 4 delta
chr16_+_56942050 0.07 ENSMUST00000166897.3
Tomm70a
translocase of outer mitochondrial membrane 70A
chr15_-_73295074 0.06 ENSMUST00000226893.2
Ptk2
PTK2 protein tyrosine kinase 2
chr16_+_8647959 0.06 ENSMUST00000023150.7
1810013L24Rik
RIKEN cDNA 1810013L24 gene
chr8_-_85807281 0.02 ENSMUST00000152785.8
Wdr83
WD repeat domain containing 83
chr5_-_31350352 0.02 ENSMUST00000202758.4
ENSMUST00000114603.8
Eif2b4
eukaryotic translation initiation factor 2B, subunit 4 delta
chr19_-_46028060 0.01 ENSMUST00000056931.14
Ldb1
LIM domain binding 1
chr9_-_108888779 0.01 ENSMUST00000061973.5
Trex1
three prime repair exonuclease 1
chr11_+_19874354 0.00 ENSMUST00000093299.13
Spred2
sprouty-related EVH1 domain containing 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.6 1.7 GO:0036275 response to 5-fluorouracil(GO:0036275)
0.4 1.2 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.4 2.1 GO:0045994 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.4 4.4 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.4 1.1 GO:0061010 gall bladder development(GO:0061010)
0.3 1.0 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.3 1.5 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.3 2.6 GO:0060214 endocardium formation(GO:0060214)
0.2 0.8 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.2 1.4 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.2 0.9 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2 1.5 GO:0002568 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.1 0.9 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.5 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.1 0.8 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 2.5 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.1 0.7 GO:0060596 mammary placode formation(GO:0060596)
0.1 2.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 1.3 GO:0001842 neural fold formation(GO:0001842)
0.1 1.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.2 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.9 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 1.5 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 1.6 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.7 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 1.1 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.5 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 2.5 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 1.2 GO:0070207 protein homotrimerization(GO:0070207)
0.0 1.9 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.0 0.4 GO:0006817 phosphate ion transport(GO:0006817)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0097132 cyclin D2-CDK6 complex(GO:0097132)
0.6 2.3 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.4 1.3 GO:0090537 CERF complex(GO:0090537)
0.4 1.5 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.9 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.9 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 1.9 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 1.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 1.0 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 1.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.8 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 2.4 GO:0005844 polysome(GO:0005844)
0.0 1.2 GO:0008305 integrin complex(GO:0008305)
0.0 2.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 2.5 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 1.1 GO:0016328 lateral plasma membrane(GO:0016328)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0098770 FBXO family protein binding(GO:0098770)
0.4 1.2 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.4 2.5 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.3 2.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.2 0.9 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 1.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 1.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 1.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 4.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 2.3 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 0.8 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 2.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.2 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.1 0.5 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 1.1 GO:0008432 JUN kinase binding(GO:0008432)
0.0 1.3 GO:0032452 histone demethylase activity(GO:0032452)
0.0 1.0 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.7 GO:0001618 virus receptor activity(GO:0001618)
0.0 1.6 GO:0070888 E-box binding(GO:0070888)
0.0 6.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.4 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.3 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.9 GO:0003684 damaged DNA binding(GO:0003684)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 2.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 2.4 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.5 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 2.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 2.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 2.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.5 REACTOME DNA REPAIR Genes involved in DNA Repair