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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Nr1h4

Z-value: 2.31

Motif logo

Transcription factors associated with Nr1h4

Gene Symbol Gene ID Gene Info
ENSMUSG00000047638.16 Nr1h4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr1h4mm39_v1_chr10_-_89369432_893694520.628.3e-09Click!

Activity profile of Nr1h4 motif

Sorted Z-values of Nr1h4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr1h4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_-_69172944 64.10 ENSMUST00000102709.8
ENSMUST00000102710.10
ENSMUST00000180142.2
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr7_-_105249308 43.78 ENSMUST00000210531.2
ENSMUST00000033185.10
hemopexin
chr1_+_67162176 35.59 ENSMUST00000027144.8
carbamoyl-phosphate synthetase 1
chr14_-_30645711 35.10 ENSMUST00000006697.17
inter-alpha trypsin inhibitor, heavy chain 3
chr6_+_141575226 32.37 ENSMUST00000042812.9
solute carrier organic anion transporter family, member 1b2
chr14_-_30645503 31.97 ENSMUST00000227995.2
inter-alpha trypsin inhibitor, heavy chain 3
chr8_-_93806593 29.80 ENSMUST00000109582.3
carboxylesterase 1B
chr1_+_171052623 29.07 ENSMUST00000111321.8
ENSMUST00000005824.12
ENSMUST00000111320.8
ENSMUST00000111319.2
apolipoprotein A-II
chr15_-_82678490 26.77 ENSMUST00000006094.6
cytochrome P450, family 2, subfamily d, polypeptide 26
chr3_+_137983250 22.82 ENSMUST00000004232.10
alcohol dehydrogenase 1 (class I)
chr17_-_84154173 22.64 ENSMUST00000000687.9
3-hydroxyanthranilate 3,4-dioxygenase
chr19_-_38113056 21.44 ENSMUST00000236283.2
retinol binding protein 4, plasma
chr9_+_46179899 20.34 ENSMUST00000121598.8
apolipoprotein A-V
chr16_-_22847808 19.03 ENSMUST00000115349.9
kininogen 2
chr16_-_22847760 18.45 ENSMUST00000039338.13
kininogen 2
chr11_-_116089866 18.22 ENSMUST00000066587.12
acyl-Coenzyme A oxidase 1, palmitoyl
chr11_-_116089595 18.14 ENSMUST00000072948.11
acyl-Coenzyme A oxidase 1, palmitoyl
chr8_+_13110921 17.95 ENSMUST00000211363.2
ENSMUST00000033822.4
protein Z, vitamin K-dependent plasma glycoprotein
chr16_-_22847829 17.81 ENSMUST00000100046.9
kininogen 2
chr15_-_82648376 17.13 ENSMUST00000055721.6
cytochrome P450, family 2, subfamily d, polypeptide 40
chr17_-_84154196 16.60 ENSMUST00000234214.2
3-hydroxyanthranilate 3,4-dioxygenase
chr12_-_103597663 15.57 ENSMUST00000121625.2
ENSMUST00000044231.12
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr17_-_32639936 15.31 ENSMUST00000170392.9
ENSMUST00000237165.2
ENSMUST00000235892.2
ENSMUST00000114455.3
peptidoglycan recognition protein 2
chr4_+_133280680 15.19 ENSMUST00000042706.3
nuclear receptor subfamily 0, group B, member 2
chr10_-_80934708 15.03 ENSMUST00000117422.2
cAMP responsive element binding protein 3-like 3
chr1_+_163979384 14.69 ENSMUST00000086040.6
coagulation factor V
chr9_+_107957621 14.48 ENSMUST00000035211.14
macrophage stimulating 1 (hepatocyte growth factor-like)
chr9_+_107957640 14.25 ENSMUST00000162886.2
macrophage stimulating 1 (hepatocyte growth factor-like)
chr16_-_22848153 14.11 ENSMUST00000232459.2
kininogen 2
chr17_-_35081456 13.76 ENSMUST00000025229.11
ENSMUST00000176203.9
ENSMUST00000128767.8
complement factor B
chr13_+_91889626 12.95 ENSMUST00000022120.5
acyl-CoA thioesterase 12
chr10_+_23770586 12.71 ENSMUST00000041416.8
vanin 1
chr5_+_137568982 12.64 ENSMUST00000196471.5
ENSMUST00000198783.5
transferrin receptor 2
chr17_-_35081129 12.48 ENSMUST00000154526.8
complement factor B
chr16_-_20549294 12.13 ENSMUST00000231826.2
ENSMUST00000076422.13
ENSMUST00000232217.2
thrombopoietin
chr7_-_30755007 12.01 ENSMUST00000206474.2
ENSMUST00000205807.2
ENSMUST00000039909.13
ENSMUST00000206305.2
ENSMUST00000205439.2
FXYD domain-containing ion transport regulator 1
chr19_+_44980565 11.85 ENSMUST00000179305.2
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr1_-_162687254 11.55 ENSMUST00000131058.8
flavin containing monooxygenase 1
chr11_+_72326337 11.51 ENSMUST00000076443.10
gamma-glutamyltransferase 6
chr9_+_108539296 11.19 ENSMUST00000035222.6
solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20
chr1_-_162687369 10.51 ENSMUST00000193078.6
flavin containing monooxygenase 1
chr17_-_57535003 10.18 ENSMUST00000177046.2
ENSMUST00000024988.15
complement component 3
chrX_-_51254129 9.94 ENSMUST00000033450.3
glypican 4
chr11_+_72326391 9.48 ENSMUST00000100903.3
gamma-glutamyltransferase 6
chr7_-_30754193 9.34 ENSMUST00000205778.2
FXYD domain-containing ion transport regulator 1
chr3_+_154302311 9.34 ENSMUST00000192462.6
ENSMUST00000029850.15
crystallin, zeta
chr1_-_162641495 9.16 ENSMUST00000144916.8
ENSMUST00000140274.2
flavin containing monooxygenase 4
chr7_-_30754223 8.91 ENSMUST00000206012.2
ENSMUST00000108110.5
FXYD domain-containing ion transport regulator 1
chr7_-_30754240 8.71 ENSMUST00000206860.2
ENSMUST00000071697.11
FXYD domain-containing ion transport regulator 1
chr4_-_141345549 8.60 ENSMUST00000053263.9
transmembrane protein 82
chr11_+_72326358 8.57 ENSMUST00000108499.2
gamma-glutamyltransferase 6
chr11_+_70410445 8.21 ENSMUST00000179000.2
glycolipid transfer protein domain containing 2
chr13_+_41013230 8.19 ENSMUST00000110191.10
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr11_+_101442961 8.04 ENSMUST00000103099.8
NBR1, autophagy cargo receptor
chr11_-_120715351 8.03 ENSMUST00000055655.9
fatty acid synthase
chr12_-_16660960 7.69 ENSMUST00000239165.2
ENSMUST00000111067.10
lipin 1
chr4_-_15149755 7.69 ENSMUST00000108273.2
N-terminal EF-hand calcium binding protein 1
chr10_+_116137277 7.44 ENSMUST00000092167.7
protein tyrosine phosphatase, receptor type, B
chr13_+_25127127 7.27 ENSMUST00000021773.13
glycosylphosphatidylinositol specific phospholipase D1
chr9_-_20791012 7.04 ENSMUST00000043726.8
angiopoietin-like 6
chr18_+_61058716 6.82 ENSMUST00000115297.8
calcium/calmodulin-dependent protein kinase II alpha
chr15_-_31367872 6.64 ENSMUST00000123325.9
ankyrin repeat domain 33B
chr11_+_66915969 6.63 ENSMUST00000079077.12
ENSMUST00000061786.6
transmembrane protein 220
chr17_-_87573294 6.42 ENSMUST00000145895.8
ENSMUST00000129616.8
ENSMUST00000155904.2
ENSMUST00000151155.8
ENSMUST00000144236.9
ENSMUST00000024963.11
multiple coagulation factor deficiency 2
chr18_+_61058684 6.21 ENSMUST00000102888.10
ENSMUST00000025519.11
calcium/calmodulin-dependent protein kinase II alpha
chr15_-_31367668 5.97 ENSMUST00000110410.10
ENSMUST00000076942.5
ankyrin repeat domain 33B
chr11_+_97576619 5.94 ENSMUST00000107584.8
ENSMUST00000107585.9
CDGSH iron sulfur domain 3
chr6_+_72391283 5.68 ENSMUST00000065906.9
gamma-glutamyl carboxylase
chr17_-_74354844 5.49 ENSMUST00000043458.9
steroid 5 alpha-reductase 2
chr7_-_99345016 5.39 ENSMUST00000107086.9
solute carrier organic anion transporter family, member 2b1
chr17_-_79328157 5.35 ENSMUST00000168887.8
ENSMUST00000119284.8
protein kinase D3
chr6_-_24528012 5.24 ENSMUST00000023851.9
NADH:ubiquinone oxidoreductase subunit A5
chr11_+_97576724 5.09 ENSMUST00000107583.3
CDGSH iron sulfur domain 3
chr13_+_41040657 5.07 ENSMUST00000069958.15
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr19_+_38995463 5.06 ENSMUST00000025966.5
cytochrome P450, family 2, subfamily c, polypeptide 55
chr15_+_102010632 5.05 ENSMUST00000229592.2
tensin 2
chrX_-_137985960 4.71 ENSMUST00000033626.15
ENSMUST00000060824.4
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr5_-_147662798 4.48 ENSMUST00000110529.6
ENSMUST00000031653.12
FMS-like tyrosine kinase 1
chr4_+_117706390 4.35 ENSMUST00000132043.9
ENSMUST00000169990.8
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr9_-_21900724 4.33 ENSMUST00000045726.8
ral guanine nucleotide dissociation stimulator-like 3
chr11_+_101443014 4.14 ENSMUST00000147239.8
NBR1, autophagy cargo receptor
chr2_-_174305856 4.00 ENSMUST00000016396.8
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
chr11_+_101443674 3.98 ENSMUST00000107213.8
ENSMUST00000107208.8
ENSMUST00000107212.8
ENSMUST00000127421.8
NBR1, autophagy cargo receptor
chr15_-_90934059 3.97 ENSMUST00000109288.9
ENSMUST00000100304.11
kinesin family member 21A
chr16_+_7011580 3.94 ENSMUST00000231194.2
RNA binding protein, fox-1 homolog (C. elegans) 1
chr4_+_117706559 3.88 ENSMUST00000163288.2
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr15_-_90934021 3.80 ENSMUST00000109287.4
ENSMUST00000067205.16
ENSMUST00000088614.13
kinesin family member 21A
chr7_-_126944578 3.71 ENSMUST00000060783.7
zinc finger protein 768
chr3_+_121761471 3.70 ENSMUST00000196479.5
ENSMUST00000197155.5
Rho GTPase activating protein 29
chr12_+_76593799 3.50 ENSMUST00000218380.2
ENSMUST00000219751.2
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr11_+_75404356 3.45 ENSMUST00000042808.13
ENSMUST00000118243.2
scavenger receptor class F, member 1
chr7_-_44320244 3.33 ENSMUST00000048102.15
myosin, heavy polypeptide 14
chr2_-_130480014 3.24 ENSMUST00000089561.10
ENSMUST00000110260.8
leucine zipper, putative tumor suppressor family member 3
chr4_-_137509493 3.23 ENSMUST00000153588.8
alkaline phosphatase, liver/bone/kidney
chr10_-_78134026 3.17 ENSMUST00000105389.8
1-acylglycerol-3-phosphate O-acyltransferase 3
chr17_+_3532455 3.16 ENSMUST00000227604.2
T cell lymphoma invasion and metastasis 2
chr2_+_175971970 3.10 ENSMUST00000135430.2
RIKEN cDNA 2210418O10 gene
chr3_-_107424637 3.07 ENSMUST00000166892.2
solute carrier family 6 (neurotransmitter transporter), member 17
chr7_-_103142086 3.06 ENSMUST00000055787.8
olfactory receptor 609
chr10_+_43777777 3.03 ENSMUST00000054418.12
reticulon 4 interacting protein 1
chr9_+_44018551 3.00 ENSMUST00000114821.9
ENSMUST00000114818.9
C1q and tumor necrosis factor related protein 5
chr9_-_106353792 2.86 ENSMUST00000214682.2
ENSMUST00000112479.9
poly (ADP-ribose) polymerase family, member 3
chrX_-_137985979 2.84 ENSMUST00000152457.2
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr1_+_153528689 2.80 ENSMUST00000041776.12
regulator of G-protein signaling 8
chr7_+_128213084 2.78 ENSMUST00000043138.13
inositol polyphosphate-5-phosphatase F
chr17_+_24888704 2.72 ENSMUST00000047179.7
zinc finger protein 598
chr18_-_67582191 2.68 ENSMUST00000025408.10
AFG3-like AAA ATPase 2
chr9_+_44018520 2.59 ENSMUST00000114816.8
C1q and tumor necrosis factor related protein 5
chr8_+_94905710 2.56 ENSMUST00000034215.8
ENSMUST00000212291.2
ENSMUST00000211807.2
metallothionein 1
chr10_+_4561974 2.54 ENSMUST00000105590.8
ENSMUST00000067086.14
estrogen receptor 1 (alpha)
chr10_-_89568106 2.50 ENSMUST00000020109.5
ARP6 actin-related protein 6
chr1_-_171074652 2.47 ENSMUST00000013737.13
ENSMUST00000111318.8
NADH:ubiquinone oxidoreductase core subunit S2
chr4_-_129015493 2.45 ENSMUST00000135763.2
ENSMUST00000149763.3
ENSMUST00000164649.8
hippocalcin
chr9_-_106533279 2.45 ENSMUST00000023959.13
ENSMUST00000201681.2
glutamate receptor, metabotropic 2
chr17_+_24888641 2.38 ENSMUST00000234956.2
zinc finger protein 598
chr6_-_41752111 2.36 ENSMUST00000214976.3
olfactory receptor 459
chr19_+_4644365 2.33 ENSMUST00000113825.4
pyruvate carboxylase
chr3_-_120965327 2.31 ENSMUST00000170781.2
ENSMUST00000039761.12
ENSMUST00000106467.8
ENSMUST00000106466.10
ENSMUST00000164925.9
RWD domain containing 3
chr2_-_85917726 2.25 ENSMUST00000216886.2
ENSMUST00000213333.2
ENSMUST00000216020.2
olfactory receptor 1037
chr11_+_95304903 2.25 ENSMUST00000107724.9
ENSMUST00000150884.8
ENSMUST00000107722.8
ENSMUST00000127713.2
speckle-type BTB/POZ protein
chr6_-_41751648 2.24 ENSMUST00000214752.2
olfactory receptor 459
chr4_-_129015682 2.22 ENSMUST00000139450.8
ENSMUST00000125931.9
ENSMUST00000116444.10
hippocalcin
chr1_-_63215952 2.21 ENSMUST00000185412.7
ENSMUST00000027111.15
ENSMUST00000189664.2
NADH:ubiquinone oxidoreductase core subunit S1
chr6_-_29380423 2.20 ENSMUST00000147483.3
opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)
chr1_-_63215812 2.14 ENSMUST00000185847.2
ENSMUST00000185732.7
ENSMUST00000188370.7
ENSMUST00000168099.9
NADH:ubiquinone oxidoreductase core subunit S1
chr5_-_129916283 2.14 ENSMUST00000094280.4
coiled-coil-helix-coiled-coil-helix domain containing 2
chr7_+_44091822 2.13 ENSMUST00000058667.15
leucine rich repeat containing 4B
chr2_+_177404691 2.13 ENSMUST00000119838.9
predicted gene 14322
chr15_-_77811935 2.08 ENSMUST00000174529.2
ENSMUST00000173631.8
thioredoxin 2
chr17_+_37716368 2.07 ENSMUST00000077008.4
olfactory receptor 107
chr3_-_108133914 2.05 ENSMUST00000141387.4
synaptophysin-like 2
chr7_-_4973960 2.00 ENSMUST00000144863.8
SH3 domain binding kinase family, member 3
chr9_-_22043083 1.88 ENSMUST00000069330.14
ENSMUST00000217643.2
acid phosphatase 5, tartrate resistant
chr8_+_93400916 1.87 ENSMUST00000034185.13
Iroquois homeobox 6
chr4_+_53440389 1.85 ENSMUST00000107646.9
ENSMUST00000102911.10
solute carrier family 44, member 1
chr11_-_102588536 1.85 ENSMUST00000164506.3
ENSMUST00000092569.13
coiled-coil domain containing 43
chr9_+_44018583 1.83 ENSMUST00000152956.8
ENSMUST00000114815.3
ENSMUST00000206295.2
ENSMUST00000206769.2
ENSMUST00000205500.2
C1q and tumor necrosis factor related protein 5
chr19_+_4644425 1.83 ENSMUST00000238089.2
pyruvate carboxylase
chr7_-_47631843 1.82 ENSMUST00000087092.4
MAS-related GPR, member A4
chr11_-_115704447 1.78 ENSMUST00000041684.11
ENSMUST00000156812.2
CASK-interacting protein 2
chr1_+_75213114 1.77 ENSMUST00000188290.7
DnaJ heat shock protein family (Hsp40) member B2
chr4_-_129015027 1.77 ENSMUST00000030572.10
hippocalcin
chr7_-_142215027 1.73 ENSMUST00000105936.8
insulin-like growth factor 2
chr7_-_4974167 1.70 ENSMUST00000133272.2
SH3 domain binding kinase family, member 3
chr1_+_75213258 1.68 ENSMUST00000185654.3
DnaJ heat shock protein family (Hsp40) member B2
chr8_+_85807369 1.68 ENSMUST00000079764.14
WD repeat domain 83 opposite strand
chr16_+_20354225 1.53 ENSMUST00000090023.13
ENSMUST00000007216.9
ENSMUST00000232001.2
adaptor-related protein complex 2, mu 1 subunit
chr14_-_52704547 1.50 ENSMUST00000205811.2
olfactory receptor 1508
chr15_-_98465516 1.49 ENSMUST00000012104.7
cyclin T1
chr5_-_37494179 1.48 ENSMUST00000114148.2
EvC ciliary complex subunit 1
chr7_-_4517559 1.48 ENSMUST00000163538.8
troponin T1, skeletal, slow
chr7_-_46783432 1.47 ENSMUST00000102626.10
protein tyrosine phosphatase, non-receptor type 5
chr5_-_37494213 1.47 ENSMUST00000031005.11
EvC ciliary complex subunit 1
chr9_+_56902172 1.41 ENSMUST00000034832.8
protein tyrosine phosphatase, non-receptor type 9
chr3_+_99147677 1.36 ENSMUST00000151606.8
T-box 15
chrM_+_8603 1.32 ENSMUST00000082409.1
mitochondrially encoded cytochrome c oxidase III
chrX_-_105528972 1.27 ENSMUST00000140707.2
fibronectin type III domain containing 3C1
chr16_+_18247666 1.26 ENSMUST00000144233.3
thioredoxin reductase 2
chr18_-_35064906 1.25 ENSMUST00000025218.8
eukaryotic translation termination factor 1
chr11_-_120520954 1.20 ENSMUST00000106180.2
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr17_+_25352353 1.19 ENSMUST00000162862.3
ENSMUST00000040729.9
chloride channel, voltage-sensitive 7
chr1_-_120197979 1.18 ENSMUST00000112639.8
STEAP family member 3
chr6_+_24528143 1.16 ENSMUST00000031696.10
ankyrin repeat and SOCS box-containing 15
chr18_+_36662276 1.16 ENSMUST00000237595.2
solute carrier family 4, sodium bicarbonate cotransporter, member 9
chr4_+_149188585 1.15 ENSMUST00000103216.10
ENSMUST00000030816.4
DNA fragmentation factor, alpha subunit
chr9_-_22042930 1.13 ENSMUST00000213815.2
acid phosphatase 5, tartrate resistant
chr16_+_32250043 1.11 ENSMUST00000115140.2
ENSMUST00000104893.10
phosphate cytidylyltransferase 1, choline, alpha isoform
chr5_+_147894121 1.09 ENSMUST00000085558.11
ENSMUST00000129092.2
microtubule associated tumor suppressor candidate 2
chrX_+_20714782 1.08 ENSMUST00000001155.11
ENSMUST00000122312.8
ENSMUST00000120356.8
ENSMUST00000122850.2
Araf proto-oncogene, serine/threonine kinase
chrX_-_18327610 1.08 ENSMUST00000044188.5
divergent protein kinase domain 2B
chr17_+_24939072 1.07 ENSMUST00000054289.13
ribosomal protein S2
chr4_+_143076327 1.05 ENSMUST00000052458.3
leucine rich repeat containing 38
chr13_-_40882417 1.01 ENSMUST00000225180.2
transcription factor AP-2, alpha
chr6_-_29380467 0.99 ENSMUST00000080428.13
opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)
chr2_+_128907854 0.98 ENSMUST00000035812.14
tubulin tyrosine ligase
chr16_-_94171556 0.97 ENSMUST00000113906.9
phosphatidylinositol glycan anchor biosynthesis, class P
chr2_-_90748331 0.96 ENSMUST00000111461.13
protein tyrosine phosphatase, mitochondrial 1
chr6_-_28449250 0.96 ENSMUST00000164519.9
ENSMUST00000171089.9
ENSMUST00000031718.14
paired box 4
chr11_+_100225233 0.93 ENSMUST00000017309.2
gastrin
chr2_+_181139016 0.91 ENSMUST00000108799.10
tumor protein D52-like 2
chr7_-_4517608 0.89 ENSMUST00000166959.8
troponin T1, skeletal, slow
chr1_+_152830720 0.83 ENSMUST00000043313.15
ENSMUST00000186621.2
nicotinamide nucleotide adenylyltransferase 2
chr12_-_87346479 0.82 ENSMUST00000125733.8
isthmin 2
chr10_-_89522112 0.81 ENSMUST00000092227.12
ENSMUST00000174252.8
SCY1-like 2 (S. cerevisiae)
chr7_+_11608557 0.81 ENSMUST00000227611.2
ENSMUST00000226622.2
ENSMUST00000228646.2
ENSMUST00000226855.2
ENSMUST00000228268.2
ENSMUST00000228463.2
vomeronasal 1 receptor 75
chrX_-_166638057 0.81 ENSMUST00000238211.2
FERM and PDZ domain containing 4
chr2_+_181138958 0.80 ENSMUST00000149163.8
ENSMUST00000000844.15
ENSMUST00000184849.8
ENSMUST00000108800.8
ENSMUST00000069712.9
tumor protein D52-like 2
chrX_-_138683102 0.80 ENSMUST00000101217.4
ripply transcriptional repressor 1
chr7_+_140226365 0.79 ENSMUST00000084456.6
ENSMUST00000211057.2
ENSMUST00000211399.2
olfactory receptor 53
chr15_+_101371353 0.73 ENSMUST00000088049.5
keratin 86
chr9_+_50664207 0.73 ENSMUST00000034562.9
crystallin, alpha B
chr13_+_38041910 0.72 ENSMUST00000138110.8
ras responsive element binding protein 1
chr2_-_176894622 0.72 ENSMUST00000133301.8
predicted gene 14410
chr7_-_45362867 0.66 ENSMUST00000211340.2
sphingosine kinase 2
chr9_+_50664288 0.64 ENSMUST00000214962.2
ENSMUST00000216755.2
crystallin, alpha B
chr3_+_87457406 0.61 ENSMUST00000238894.2
ets variant 3-like
chr13_-_18167890 0.61 ENSMUST00000099735.6
Yae1 domain containing 1
chr2_+_175664894 0.57 ENSMUST00000109012.4
predicted gene 6710
chr2_-_175044854 0.55 ENSMUST00000165892.8
predicted gene 14391
chr16_+_32249713 0.54 ENSMUST00000115137.8
ENSMUST00000079791.11
phosphate cytidylyltransferase 1, choline, alpha isoform

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
12.4 49.4 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
9.2 64.1 GO:0046618 drug export(GO:0046618)
6.3 43.8 GO:0015886 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) heme transport(GO:0015886) positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
6.1 36.4 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
5.7 22.8 GO:0006069 ethanol oxidation(GO:0006069)
5.1 35.6 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
4.4 39.2 GO:0046874 quinolinate metabolic process(GO:0046874)
4.3 21.4 GO:0048807 female genitalia morphogenesis(GO:0048807)
3.5 39.0 GO:1903278 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278) positive regulation of inorganic anion transmembrane transport(GO:1903797)
3.2 28.7 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
3.0 12.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
2.7 8.2 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
2.6 15.3 GO:0032827 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
2.5 10.2 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
2.5 7.6 GO:0033189 response to vitamin A(GO:0033189)
2.1 6.4 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
2.1 29.6 GO:0006751 glutathione catabolic process(GO:0006751)
2.0 32.4 GO:0006857 oligopeptide transport(GO:0006857)
1.9 13.3 GO:0036438 maintenance of lens transparency(GO:0036438)
1.8 7.3 GO:0010982 GPI anchor release(GO:0006507) regulation of high-density lipoprotein particle clearance(GO:0010982)
1.7 26.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
1.4 67.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
1.4 5.7 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187)
1.3 87.4 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
1.3 9.2 GO:0042737 drug catabolic process(GO:0042737)
1.2 22.1 GO:0070995 NADPH oxidation(GO:0070995)
1.1 12.6 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
1.1 5.4 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
1.0 11.2 GO:0015879 carnitine transport(GO:0015879)
1.0 8.0 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
1.0 15.0 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.9 13.0 GO:0098970 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.8 4.2 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.8 2.3 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.8 5.4 GO:0089700 protein kinase D signaling(GO:0089700)
0.7 5.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.7 12.7 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.7 49.0 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.6 7.7 GO:0006642 triglyceride mobilization(GO:0006642)
0.6 5.5 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.6 4.5 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.5 2.5 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.5 3.5 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.5 1.5 GO:2001025 positive regulation of response to drug(GO:2001025)
0.5 2.7 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.4 9.3 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.4 2.4 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.4 2.8 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.4 3.1 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.4 3.0 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.4 2.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.3 12.9 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
0.3 2.6 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.3 1.5 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.2 2.7 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.2 1.9 GO:0015871 choline transport(GO:0015871)
0.2 1.2 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.2 3.4 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.2 3.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.2 16.2 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.2 11.8 GO:0050919 negative chemotaxis(GO:0050919)
0.2 1.0 GO:0003409 optic cup structural organization(GO:0003409)
0.2 2.8 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.2 4.6 GO:0014850 response to muscle activity(GO:0014850)
0.2 2.1 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.2 0.7 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.2 0.8 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.2 1.9 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 15.2 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 1.7 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 2.1 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.1 0.8 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 12.6 GO:0022904 respiratory electron transport chain(GO:0022904)
0.1 1.5 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 4.0 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 1.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 1.0 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 0.7 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.8 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 3.9 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.1 3.3 GO:0071625 vocalization behavior(GO:0071625)
0.1 19.0 GO:0007596 blood coagulation(GO:0007596)
0.1 3.2 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 2.9 GO:0003416 endochondral bone growth(GO:0003416)
0.1 1.3 GO:0006415 translational termination(GO:0006415)
0.1 1.7 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 0.5 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.1 0.4 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.1 1.2 GO:0015677 copper ion import(GO:0015677)
0.1 1.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 1.0 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 4.8 GO:0070206 protein trimerization(GO:0070206)
0.0 0.8 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 2.4 GO:0014047 glutamate secretion(GO:0014047)
0.0 1.3 GO:0000305 response to oxygen radical(GO:0000305)
0.0 0.2 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.0 2.1 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 1.4 GO:0048701 embryonic cranial skeleton morphogenesis(GO:0048701)
0.0 0.2 GO:1900740 positive regulation of thymocyte apoptotic process(GO:0070245) regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 1.2 GO:0009268 response to pH(GO:0009268)
0.0 2.4 GO:0030641 regulation of cellular pH(GO:0030641)
0.0 0.1 GO:0022601 menstrual cycle phase(GO:0022601)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 7.6 GO:0001525 angiogenesis(GO:0001525)
0.0 0.4 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 2.5 GO:0006338 chromatin remodeling(GO:0006338)
0.0 1.0 GO:0031016 pancreas development(GO:0031016)
0.0 1.1 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 64.1 GO:0046581 intercellular canaliculus(GO:0046581)
3.3 13.0 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
2.1 49.4 GO:0042627 chylomicron(GO:0042627)
1.0 12.6 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.9 9.7 GO:0042587 glycogen granule(GO:0042587)
0.7 2.7 GO:0005745 m-AAA complex(GO:0005745)
0.6 35.6 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.5 4.0 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.5 133.6 GO:0072562 blood microparticle(GO:0072562)
0.5 14.7 GO:0031091 platelet alpha granule(GO:0031091)
0.5 3.3 GO:0097513 myosin II filament(GO:0097513)
0.4 34.6 GO:0034707 chloride channel complex(GO:0034707)
0.4 6.4 GO:0044327 dendritic spine head(GO:0044327)
0.4 7.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.4 36.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.4 2.5 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.3 16.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.3 1.4 GO:0070722 Tle3-Aes complex(GO:0070722)
0.3 5.5 GO:0070852 cell body fiber(GO:0070852)
0.2 12.1 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 1.5 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.2 3.2 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.1 2.7 GO:0005861 troponin complex(GO:0005861)
0.1 3.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 7.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.4 GO:0097441 basilar dendrite(GO:0097441)
0.1 1.5 GO:1990635 proximal dendrite(GO:1990635)
0.1 1.4 GO:0097512 cardiac myofibril(GO:0097512)
0.1 2.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.5 GO:0017177 glucosidase II complex(GO:0017177)
0.1 4.3 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 34.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 20.5 GO:0031225 anchored component of membrane(GO:0031225)
0.1 7.8 GO:0005871 kinesin complex(GO:0005871)
0.1 60.6 GO:0031966 mitochondrial membrane(GO:0031966)
0.1 2.1 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 2.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.5 GO:0000235 astral microtubule(GO:0000235)
0.1 0.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 1.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 2.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 2.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 91.0 GO:0005615 extracellular space(GO:0005615)
0.0 1.2 GO:0005771 multivesicular body(GO:0005771)
0.0 16.7 GO:0098793 presynapse(GO:0098793)
0.0 3.5 GO:0016234 inclusion body(GO:0016234)
0.0 7.4 GO:0043235 receptor complex(GO:0043235)
0.0 78.7 GO:0070062 extracellular exosome(GO:0070062)
0.0 2.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 3.8 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 3.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.2 GO:0005740 mitochondrial envelope(GO:0005740)
0.0 20.3 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 15.6 GO:0005739 mitochondrion(GO:0005739)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
11.9 35.6 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
7.6 22.8 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
7.3 43.8 GO:0015232 heme transporter activity(GO:0015232)
7.3 29.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
7.1 21.4 GO:0034632 retinol transporter activity(GO:0034632)
5.2 36.4 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
4.4 101.9 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
3.4 20.3 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) lipoprotein lipase activator activity(GO:0060230)
3.3 13.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
2.7 8.0 GO:0016296 [acyl-carrier-protein] S-malonyltransferase activity(GO:0004314) oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297) S-acetyltransferase activity(GO:0016418) S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420) phosphopantetheine binding(GO:0031177)
2.6 31.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
2.6 12.9 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
2.6 15.3 GO:0016019 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
2.5 12.6 GO:0004998 transferrin receptor activity(GO:0004998)
2.5 29.6 GO:0036374 glutathione hydrolase activity(GO:0036374)
2.3 9.3 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
1.9 11.2 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
1.6 12.7 GO:0034235 GPI anchor binding(GO:0034235)
1.5 39.2 GO:0019825 oxygen binding(GO:0019825)
1.4 5.5 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
1.3 5.1 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
1.0 4.2 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.9 26.8 GO:0070330 aromatase activity(GO:0070330)
0.8 2.5 GO:0038052 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.8 7.3 GO:0004630 phospholipase D activity(GO:0004630)
0.8 22.9 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.8 15.0 GO:0035497 cAMP response element binding(GO:0035497)
0.7 4.3 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.6 4.5 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.6 8.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.6 90.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.6 67.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.6 2.8 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.5 8.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.5 2.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.5 39.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.5 3.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.4 10.2 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.4 15.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.4 1.7 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.4 17.1 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.3 72.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.3 9.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.3 7.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3 3.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.3 2.7 GO:0031014 troponin T binding(GO:0031014)
0.3 1.9 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.2 2.4 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.2 5.4 GO:0004697 protein kinase C activity(GO:0004697)
0.2 2.4 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.2 13.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.2 4.0 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 17.2 GO:0005507 copper ion binding(GO:0005507)
0.2 3.0 GO:0003993 acid phosphatase activity(GO:0003993)
0.2 3.4 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.2 1.3 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 1.2 GO:0000293 ferric-chelate reductase activity(GO:0000293) cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 3.5 GO:0070628 proteasome binding(GO:0070628)
0.1 3.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.8 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 26.4 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.1 3.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.5 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 5.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 2.2 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 1.0 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.1 0.7 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 1.3 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 1.0 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 5.1 GO:0043022 ribosome binding(GO:0043022)
0.1 0.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 1.0 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 1.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 1.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 2.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 7.2 GO:0005179 hormone activity(GO:0005179)
0.0 5.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 2.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 6.9 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.5 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 1.8 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 1.0 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 1.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.1 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 2.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.6 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 5.3 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 2.1 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.4 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.0 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 2.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 25.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
1.1 39.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.4 4.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.4 28.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.3 70.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3 90.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 0.9 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.2 7.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 8.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 2.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 12.4 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 2.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.7 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.2 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.0 PID CASPASE PATHWAY Caspase cascade in apoptosis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
5.4 59.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
2.8 39.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
2.6 36.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
1.8 23.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
1.7 49.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
1.5 36.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
1.2 14.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.5 9.9 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.5 8.0 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.5 11.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.4 4.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.4 5.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.4 13.0 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.4 7.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.4 5.5 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.4 22.1 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.3 7.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.3 3.2 REACTOME OPSINS Genes involved in Opsins
0.2 3.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.2 4.0 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.2 17.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 12.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 6.4 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 2.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 27.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 3.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 5.1 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.1 1.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 3.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 3.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.5 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 2.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.2 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.3 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.2 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 2.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors