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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Nr2c1

Z-value: 0.70

Motif logo

Transcription factors associated with Nr2c1

Gene Symbol Gene ID Gene Info
ENSMUSG00000005897.15 Nr2c1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr2c1mm39_v1_chr10_+_93983844_93983885-0.326.9e-03Click!

Activity profile of Nr2c1 motif

Sorted Z-values of Nr2c1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr2c1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr8_-_124621483 4.09 ENSMUST00000034453.6
ENSMUST00000212584.2
actin, alpha 1, skeletal muscle
chr11_+_98274637 3.79 ENSMUST00000008021.3
titin-cap
chr16_-_4340920 3.74 ENSMUST00000090500.10
ENSMUST00000023161.8
sarcalumenin
chr7_+_139673300 3.07 ENSMUST00000026540.9
proline-rich acidic protein 1
chr4_+_156300325 2.72 ENSMUST00000105572.3
PPARGC1 and ESRR induced regulator, muscle 1
chr8_+_55024446 2.65 ENSMUST00000239166.2
ENSMUST00000239106.2
ENSMUST00000239152.2
ankyrin repeat and SOCs box-containing 5
chr2_+_110427643 2.62 ENSMUST00000045972.13
ENSMUST00000111026.3
solute carrier family 5 (sodium/glucose cotransporter), member 12
chr13_-_73476561 2.61 ENSMUST00000222930.2
ENSMUST00000223293.2
ENSMUST00000022097.6
NADH:ubiquinone oxidoreductase core subunit S6
chr17_-_67939702 2.53 ENSMUST00000097290.4
leucine rich repeat containing 30
chr19_+_53781721 2.24 ENSMUST00000162910.2
RNA binding motif protein 20
chr4_-_41048124 2.24 ENSMUST00000030136.13
aquaporin 7
chr16_-_32306683 1.94 ENSMUST00000042042.9
solute carrier family 51, alpha subunit
chr14_+_75373766 1.87 ENSMUST00000145303.8
lymphocyte cytosolic protein 1
chr3_+_129007599 1.85 ENSMUST00000042587.12
paired-like homeodomain transcription factor 2
chr8_-_123187406 1.85 ENSMUST00000006762.7
snail family zinc finger 3
chr15_+_79975520 1.70 ENSMUST00000009728.13
ENSMUST00000009727.12
synaptogyrin 1
chr9_+_107217786 1.62 ENSMUST00000042581.4
RIKEN cDNA 6430571L13 gene
chr1_-_59012579 1.54 ENSMUST00000173590.2
ENSMUST00000027186.12
trafficking protein, kinesin binding 2
chr15_+_101026454 1.53 ENSMUST00000117984.8
activin A receptor, type II-like 1
chr14_-_70414236 1.47 ENSMUST00000153735.8
PDZ and LIM domain 2
chr9_-_107483855 1.47 ENSMUST00000073448.12
ENSMUST00000194606.2
ENSMUST00000195662.6
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr7_-_79492091 1.43 ENSMUST00000049004.8
alanyl (membrane) aminopeptidase
chr15_+_101026803 1.43 ENSMUST00000119063.8
ENSMUST00000121718.8
activin A receptor, type II-like 1
chr1_-_74544946 1.42 ENSMUST00000044260.11
ENSMUST00000186282.7
ubiquitin specific peptidase 37
chr9_+_118335294 1.31 ENSMUST00000084820.6
golgi autoantigen, golgin subfamily a, 4
chr7_-_19684654 1.27 ENSMUST00000043440.8
immunoglobulin superfamily, member 23
chr7_+_45546365 1.23 ENSMUST00000069772.16
ENSMUST00000210503.2
ENSMUST00000209350.2
transmembrane protein 143
chr12_-_115083839 1.17 ENSMUST00000103521.3
immunoglobulin heavy variable 1-50
chr11_-_107228382 1.15 ENSMUST00000040380.13
phosphatidylinositol transfer protein, cytoplasmic 1
chr3_+_129007917 1.15 ENSMUST00000174623.3
paired-like homeodomain transcription factor 2
chr10_+_75152705 1.15 ENSMUST00000105420.3
adenosine A2a receptor
chr3_+_96737385 1.13 ENSMUST00000058865.14
PDZ domain containing 1
chr12_-_83534482 1.13 ENSMUST00000177959.8
ENSMUST00000178756.8
D4, zinc and double PHD fingers, family 3
chr5_-_137101108 1.11 ENSMUST00000077523.4
ENSMUST00000041388.11
serine (or cysteine) peptidase inhibitor, clade E, member 1
chr17_+_35413415 1.03 ENSMUST00000025262.6
ENSMUST00000173600.2
lymphotoxin B
chr6_-_142910094 1.02 ENSMUST00000032421.4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr1_+_74545203 1.02 ENSMUST00000087215.7
CCR4-NOT transcription complex, subunit 9
chrX_+_99773523 1.00 ENSMUST00000019503.14
glycerophosphodiester phosphodiesterase domain containing 2
chr2_-_62404195 0.98 ENSMUST00000174234.8
ENSMUST00000000402.16
ENSMUST00000174448.8
ENSMUST00000102732.10
fibroblast activation protein
chr14_+_75373915 0.97 ENSMUST00000122840.8
lymphocyte cytosolic protein 1
chr10_-_23226684 0.96 ENSMUST00000220299.2
EYA transcriptional coactivator and phosphatase 4
chr17_-_13211075 0.94 ENSMUST00000159986.8
ENSMUST00000007007.14
Wilms tumour 1-associating protein
chr19_-_6899173 0.92 ENSMUST00000025906.12
ENSMUST00000239322.2
estrogen related receptor, alpha
chr4_+_97665992 0.90 ENSMUST00000107062.9
ENSMUST00000052018.12
ENSMUST00000107057.8
nuclear factor I/A
chr17_-_46343291 0.89 ENSMUST00000071648.12
ENSMUST00000142351.9
vascular endothelial growth factor A
chr1_+_59012680 0.89 ENSMUST00000114296.8
ENSMUST00000027185.11
STE20-related kinase adaptor beta
chr17_-_13211374 0.88 ENSMUST00000159551.8
ENSMUST00000160781.8
Wilms tumour 1-associating protein
chr15_-_102579463 0.87 ENSMUST00000185641.7
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)
chr3_+_68479578 0.84 ENSMUST00000170788.9
schwannomin interacting protein 1
chr15_-_76396151 0.81 ENSMUST00000023214.11
diacylglycerol O-acyltransferase 1
chr1_+_58625539 0.81 ENSMUST00000027193.9
NADH:ubiquinone oxidoreductase subunit B3
chr10_+_75152908 0.79 ENSMUST00000219044.2
adenosine A2a receptor
chr17_+_75772475 0.75 ENSMUST00000095204.6
RAS, guanyl releasing protein 3
chr4_-_11076159 0.75 ENSMUST00000058183.9
NADH:ubiquinone oxidoreductase complex assembly factor 6
chr4_+_97665843 0.74 ENSMUST00000075448.13
ENSMUST00000092532.13
nuclear factor I/A
chr17_-_52117894 0.73 ENSMUST00000176669.8
special AT-rich sequence binding protein 1
chr1_-_164285914 0.72 ENSMUST00000027863.13
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr4_+_131600918 0.70 ENSMUST00000053819.6
serine and arginine-rich splicing factor 4
chr12_+_84034628 0.70 ENSMUST00000021649.8
acyl-CoA thioesterase 2
chr3_-_79535966 0.68 ENSMUST00000120992.8
electron transferring flavoprotein, dehydrogenase
chr7_+_108533613 0.66 ENSMUST00000033342.7
eukaryotic translation initiation factor 3, subunit F
chr11_-_63970270 0.62 ENSMUST00000049091.9
heme A:farnesyltransferase cytochrome c oxidase assembly factor 10
chr7_-_82297676 0.61 ENSMUST00000207693.2
ENSMUST00000056728.5
ENSMUST00000156720.8
ENSMUST00000126478.2
stabilizer of axonemal microtubules 2
chr9_-_65298934 0.58 ENSMUST00000068307.4
kelch repeat and BTB (POZ) domain containing 13
chr7_+_28580847 0.57 ENSMUST00000066880.6
calpain 12
chr15_-_76093256 0.56 ENSMUST00000071869.12
ENSMUST00000170915.2
plectin
chrX_-_58612709 0.56 ENSMUST00000124402.2
fibroblast growth factor 13
chr9_+_121126562 0.56 ENSMUST00000238988.2
ENSMUST00000210798.3
ENSMUST00000211439.2
trafficking protein, kinesin binding 1
chr6_-_83030759 0.55 ENSMUST00000134606.8
HtrA serine peptidase 2
chr14_-_51162083 0.55 ENSMUST00000160375.8
ENSMUST00000162177.8
O-sialoglycoprotein endopeptidase
chr2_+_153850177 0.55 ENSMUST00000048103.9
ENSMUST00000145388.2
BPI fold containing family A, member 2
chr6_-_128252540 0.54 ENSMUST00000130454.8
TEA domain family member 4
chr19_-_6899121 0.54 ENSMUST00000173635.2
estrogen related receptor, alpha
chr4_-_130068484 0.53 ENSMUST00000132545.3
ENSMUST00000175992.8
ENSMUST00000105999.9
tubulointerstitial nephritis antigen-like 1
chr7_+_29931735 0.52 ENSMUST00000108193.2
ENSMUST00000108192.2
polymerase (RNA) II (DNA directed) polypeptide I
chr9_-_50571080 0.51 ENSMUST00000034567.4
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
chr4_-_106360302 0.50 ENSMUST00000177702.2
transmembrane protein 61
chr5_+_145060489 0.50 ENSMUST00000136074.2
actin related protein 2/3 complex, subunit 1B
chr10_-_93425553 0.49 ENSMUST00000020203.7
small nuclear ribonucleoprotein polypeptide F
chr14_-_51162346 0.48 ENSMUST00000159292.8
O-sialoglycoprotein endopeptidase
chr8_-_22550035 0.48 ENSMUST00000110738.3
ATPase, Cu++ transporting, beta polypeptide
chr8_-_22550321 0.48 ENSMUST00000006742.11
ATPase, Cu++ transporting, beta polypeptide
chr7_+_29931309 0.46 ENSMUST00000019882.16
ENSMUST00000149654.8
polymerase (RNA) II (DNA directed) polypeptide I
chr3_+_32583681 0.45 ENSMUST00000147350.8
mitofusin 1
chr2_-_104573179 0.44 ENSMUST00000028595.8
DEP domain containing 7
chr5_+_137628377 0.44 ENSMUST00000175968.8
leucine-rich repeats and calponin homology (CH) domain containing 4
chr14_-_52252003 0.41 ENSMUST00000226522.2
zinc finger protein 219
chr3_+_32583602 0.41 ENSMUST00000091257.11
mitofusin 1
chr3_-_8988854 0.40 ENSMUST00000042148.6
mitochondrial ribosomal protein S28
chr8_+_121395047 0.39 ENSMUST00000181795.2
cytochrome c oxidase subunit 4I1
chr11_+_4936824 0.39 ENSMUST00000109897.8
ENSMUST00000009234.16
adaptor protein complex AP-1, beta 1 subunit
chr12_+_35975619 0.38 ENSMUST00000042101.5
ENSMUST00000154042.2
anterior gradient 3
chr2_+_22785593 0.38 ENSMUST00000152170.8
prenyl (solanesyl) diphosphate synthase, subunit 1
chr1_-_172460497 0.37 ENSMUST00000027826.7
dual specificity phosphatase 23
chr11_-_99494134 0.36 ENSMUST00000072306.4
predicted gene 11938
chr6_-_83031358 0.36 ENSMUST00000113962.8
ENSMUST00000089645.13
ENSMUST00000113963.8
HtrA serine peptidase 2
chr15_+_86098660 0.36 ENSMUST00000063414.9
TBC1 domain family, member 22a
chrX_-_101232978 0.36 ENSMUST00000033683.8
ribosomal protein S4, X-linked
chr3_+_86131970 0.35 ENSMUST00000192145.6
ENSMUST00000194759.6
ENSMUST00000107635.7
LPS-responsive beige-like anchor
chr17_+_57369490 0.34 ENSMUST00000163628.2
crumbs family member 3
chr15_+_79025523 0.34 ENSMUST00000040077.8
polymerase (RNA) II (DNA directed) polypeptide F
chr15_-_79025387 0.33 ENSMUST00000187550.7
ENSMUST00000188562.7
ENSMUST00000190509.7
ENSMUST00000190730.7
ENSMUST00000190959.7
ENSMUST00000169604.8
ENSMUST00000186053.7
RIKEN cDNA 1700088E04 gene
chr11_-_97657327 0.32 ENSMUST00000107579.2
ENSMUST00000018685.9
CWC25 spliceosome-associated protein
chr12_+_37291728 0.32 ENSMUST00000160768.8
alkylglycerol monooxygenase
chr15_+_81695615 0.31 ENSMUST00000023024.8
thyrotroph embryonic factor
chr10_+_41395410 0.30 ENSMUST00000019962.15
CD164 antigen
chr17_-_27816151 0.30 ENSMUST00000231742.2
nudix (nucleotide diphosphate linked moiety X)-type motif 3
chr19_+_4147391 0.29 ENSMUST00000174514.2
ENSMUST00000174149.8
CDK2-associated protein 2
chr2_+_22785534 0.29 ENSMUST00000053729.14
prenyl (solanesyl) diphosphate synthase, subunit 1
chr4_-_82939330 0.29 ENSMUST00000071708.12
Fras1 related extracellular matrix protein 1
chr2_+_109522781 0.28 ENSMUST00000111050.10
brain derived neurotrophic factor
chr2_-_19558719 0.28 ENSMUST00000062060.5
RIKEN cDNA 4921504E06 gene
chr13_+_73476629 0.27 ENSMUST00000221730.2
mitochondrial ribosomal protein L36
chr7_+_79836581 0.27 ENSMUST00000032754.9
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr13_+_104424359 0.27 ENSMUST00000065766.7
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6
chr17_-_34247016 0.27 ENSMUST00000236627.2
ENSMUST00000237759.2
ENSMUST00000045467.14
ENSMUST00000114303.4
H2-K region expressed gene 6
chr17_+_75772567 0.27 ENSMUST00000234660.2
RAS, guanyl releasing protein 3
chr5_-_121974325 0.26 ENSMUST00000137682.2
SH2B adaptor protein 3
chr7_+_43600038 0.25 ENSMUST00000072204.5
kallikrein 1-related peptidase b8
chr6_+_83031502 0.24 ENSMUST00000092618.9
ancient ubiquitous protein 1
chr1_-_155627430 0.23 ENSMUST00000195275.2
LIM homeobox protein 4
chr10_-_4382311 0.23 ENSMUST00000126102.8
ENSMUST00000131853.2
ENSMUST00000042251.11
required for meiotic nuclear division 1 homolog
chr7_+_43910845 0.23 ENSMUST00000124863.4
predicted gene 15517
chr7_-_28297565 0.22 ENSMUST00000040531.9
ENSMUST00000108283.8
sterile alpha motif domain containing 4B
p21 (RAC1) activated kinase 4
chr10_+_58207229 0.22 ENSMUST00000238939.2
LIM and senescent cell antigen-like domains 1
chr17_+_38110779 0.22 ENSMUST00000215168.2
ENSMUST00000216478.2
olfactory receptor 124
chr17_-_35454729 0.21 ENSMUST00000048994.7
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1
chr4_+_138606671 0.21 ENSMUST00000105804.2
phospholipase A2, group IIE
chr5_+_135216090 0.21 ENSMUST00000002825.6
bromodomain adjacent to zinc finger domain, 1B
chr19_+_5687503 0.20 ENSMUST00000025867.6
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr17_+_7292967 0.20 ENSMUST00000097422.6
predicted gene 1604b
chr6_+_125122172 0.20 ENSMUST00000119527.8
ENSMUST00000117675.8
intermediate filament family orphan 1
chr7_-_45570674 0.19 ENSMUST00000210939.2
epithelial membrane protein 3
chr19_-_45986919 0.18 ENSMUST00000045396.9
armadillo-like helical domain containing 3
chr11_-_62172164 0.18 ENSMUST00000072916.5
zinc finger SWIM-type containing 7
chr7_-_45570254 0.18 ENSMUST00000164119.3
epithelial membrane protein 3
chr4_+_117581609 0.17 ENSMUST00000203629.2
ENSMUST00000204276.2
predicted gene 12845
chr11_+_116744578 0.17 ENSMUST00000021173.14
major facilitator superfamily domain containing 11
chr7_+_101043568 0.16 ENSMUST00000098243.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr14_+_58036093 0.16 ENSMUST00000111267.2
Sin3-associated polypeptide 18
chr14_-_52252318 0.16 ENSMUST00000228051.2
zinc finger protein 219
chr7_-_45570828 0.16 ENSMUST00000038876.13
epithelial membrane protein 3
chr9_+_44398524 0.15 ENSMUST00000218183.2
B cell CLL/lymphoma 9-like
chr9_-_35755446 0.15 ENSMUST00000054175.7
prostate and testis expressed 5
chr13_-_18118736 0.13 ENSMUST00000009003.9
v-ral simian leukemia viral oncogene A (ras related)
chr11_-_24025054 0.13 ENSMUST00000068360.2
RIKEN cDNA A830031A19 gene
chr15_-_102274781 0.12 ENSMUST00000078508.7
Sp7 transcription factor 7
chr12_+_37292029 0.12 ENSMUST00000160390.2
alkylglycerol monooxygenase
chr7_-_45570538 0.10 ENSMUST00000210297.2
epithelial membrane protein 3
chr10_-_129010923 0.10 ENSMUST00000169800.4
olfactory receptor 772
chrX_+_10351360 0.09 ENSMUST00000076354.13
ENSMUST00000115526.2
tetraspanin 7
chr3_+_122298308 0.09 ENSMUST00000199358.2
breast cancer anti-estrogen resistance 3
chr16_+_3648742 0.08 ENSMUST00000214238.2
ENSMUST00000214590.2
olfactory receptor 15
chr14_+_58036071 0.08 ENSMUST00000111268.8
Sin3-associated polypeptide 18
chr11_+_62172283 0.08 ENSMUST00000101075.11
ENSMUST00000050646.13
tetratricopeptide repeat domain 19
chr2_+_158636727 0.08 ENSMUST00000029186.14
ENSMUST00000109478.9
ENSMUST00000156893.2
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr1_-_58625431 0.07 ENSMUST00000161000.2
ENSMUST00000161600.8
family with sequence similarity 126, member B
chr11_-_115698894 0.07 ENSMUST00000132780.8
CASK-interacting protein 2
chr11_-_100098333 0.06 ENSMUST00000007272.8
keratin 14
chr13_-_55718899 0.06 ENSMUST00000225240.3
ENSMUST00000021957.8
family with sequence similarity 193, member B
chr3_+_58433236 0.06 ENSMUST00000029387.15
eukaryotic translation initiation factor 2A
chr2_-_63928339 0.06 ENSMUST00000131615.9
fidgetin
chr16_-_58850641 0.05 ENSMUST00000216415.2
ENSMUST00000206463.3
olfactory receptor 186
chr19_+_10914517 0.05 ENSMUST00000037261.4
prostaglandin D2 receptor 2
chr4_-_117109074 0.03 ENSMUST00000165128.9
armadillo-like helical domain containing 1
chr14_+_58035640 0.03 ENSMUST00000111269.2
Sin3-associated polypeptide 18
chr4_-_137084973 0.01 ENSMUST00000030417.10
ENSMUST00000051477.13
cell division cycle 42
chr2_-_128890092 0.00 ENSMUST00000145798.4
vinculin/alpha-catenin family member 1
chr2_+_153187729 0.00 ENSMUST00000227428.2
ENSMUST00000109790.2
ASXL transcriptional regulator 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.7 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.7 7.9 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.6 3.0 GO:0021763 subthalamic nucleus development(GO:0021763) superior vena cava morphogenesis(GO:0060578)
0.4 2.2 GO:0070295 glycerol transport(GO:0015793) renal water absorption(GO:0070295)
0.4 1.9 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.4 1.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.3 1.0 GO:0097325 regulation of collagen catabolic process(GO:0010710) melanocyte proliferation(GO:0097325)
0.3 1.0 GO:0015680 intracellular copper ion transport(GO:0015680)
0.3 0.9 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.3 0.9 GO:0038190 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190)
0.3 0.8 GO:1901738 regulation of vitamin A metabolic process(GO:1901738)
0.3 1.0 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.2 3.0 GO:0090500 lymphatic endothelial cell differentiation(GO:0060836) endocardial cushion to mesenchymal transition(GO:0090500)
0.2 0.7 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.2 0.9 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.2 1.0 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.2 1.5 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.1 1.2 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 2.7 GO:0014850 response to muscle activity(GO:0014850)
0.1 2.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.8 GO:0080009 mRNA methylation(GO:0080009)
0.1 0.6 GO:0018343 protein farnesylation(GO:0018343)
0.1 2.8 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.6 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.1 0.5 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.1 1.1 GO:0015879 carnitine transport(GO:0015879)
0.1 1.0 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 0.6 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 0.3 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.1 1.6 GO:0072189 ureter development(GO:0072189)
0.1 1.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.2 GO:0098749 cerebellar neuron development(GO:0098749)
0.1 1.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.7 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 1.4 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.1 1.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.5 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 1.9 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 1.0 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.2 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 1.1 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 1.6 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 2.2 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.7 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.7 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.7 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 1.7 GO:0050919 negative chemotaxis(GO:0050919)
0.0 1.5 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.9 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.4 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.7 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 1.3 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.2 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.6 GO:0032060 bleb assembly(GO:0032060)
0.0 0.9 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.2 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.2 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.1 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.3 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.1 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 1.0 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.5 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.2 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0036396 MIS complex(GO:0036396)
0.2 1.1 GO:0042583 chromaffin granule(GO:0042583)
0.2 0.5 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 0.7 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 0.5 GO:0036284 tubulobulbar complex(GO:0036284)
0.1 1.0 GO:0071438 invadopodium membrane(GO:0071438)
0.1 1.0 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 1.4 GO:0031983 vesicle lumen(GO:0031983)
0.1 1.0 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 1.9 GO:0032279 asymmetric synapse(GO:0032279)
0.1 2.8 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.5 GO:0005683 U7 snRNP(GO:0005683)
0.1 0.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 4.1 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 3.4 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.7 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.9 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 0.9 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.1 1.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 1.1 GO:0071565 nBAF complex(GO:0071565)
0.0 1.1 GO:0031528 microvillus membrane(GO:0031528)
0.0 3.7 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 1.0 GO:0070069 cytochrome complex(GO:0070069)
0.0 1.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.6 GO:0016528 sarcoplasm(GO:0016528)
0.0 0.6 GO:1904115 axon cytoplasm(GO:1904115)
0.0 1.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 2.2 GO:0031526 brush border membrane(GO:0031526)
0.0 3.6 GO:0030018 Z disc(GO:0030018)
0.0 1.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.3 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.9 GO:0016235 aggresome(GO:0016235)
0.0 1.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.6 GO:0014704 intercalated disc(GO:0014704)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.8 GO:0051373 FATZ binding(GO:0051373)
0.4 2.2 GO:0015254 glycerol channel activity(GO:0015254)
0.4 3.0 GO:0016361 activin receptor activity, type I(GO:0016361)
0.3 1.0 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.3 0.9 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.3 2.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 1.0 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.2 0.8 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.2 1.0 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 0.5 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.2 0.7 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.2 1.9 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.4 GO:0050479 glyceryl-ether monooxygenase activity(GO:0050479)
0.1 1.1 GO:0005124 scavenger receptor binding(GO:0005124)
0.1 0.7 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 1.0 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 1.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.3 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 1.5 GO:0038191 neuropilin binding(GO:0038191)
0.1 2.1 GO:0050811 GABA receptor binding(GO:0050811)
0.1 1.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.6 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 1.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.7 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 1.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.0 0.3 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.3 GO:0070404 NADH binding(GO:0070404)
0.0 3.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.7 GO:0030955 potassium ion binding(GO:0030955)
0.0 1.3 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 1.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.0 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.0 1.7 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.4 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.6 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.1 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 1.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 3.0 PID ALK1 PATHWAY ALK1 signaling events
0.1 3.2 ST GAQ PATHWAY G alpha q Pathway
0.1 4.1 PID RHOA PATHWAY RhoA signaling pathway
0.1 2.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 2.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.0 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.9 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.4 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 0.9 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.9 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 1.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 4.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 3.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.9 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.7 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0 1.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS