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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap
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Results for Nr2e1
Z-value: 1.84
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Transcription factors associated with Nr2e1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Nr2e1 | mm39_v1_chr10_-_42459624_42459635 | -0.12 | 3.1e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of Nr2e1
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr4_-_60457902 Show fit | 38.06 |
ENSMUST00000084548.11
ENSMUST00000103012.10 ENSMUST00000107499.4 |
major urinary protein 1 |
|
| chr4_-_62005498 Show fit | 34.84 |
ENSMUST00000107488.4
ENSMUST00000107472.8 ENSMUST00000084531.11 |
major urinary protein 3 |
|
| chr4_-_60777462 Show fit | 30.91 |
ENSMUST00000211875.2
|
major urinary protein 22 |
|
| chr4_-_61437704 Show fit | 29.88 |
ENSMUST00000095051.6
ENSMUST00000107483.8 |
major urinary protein 16 |
|
| chr4_-_60697274 Show fit | 27.04 |
ENSMUST00000117932.2
|
major urinary protein 12 |
|
| chr3_+_96432479 Show fit | 25.55 |
ENSMUST00000049208.11
|
hemojuvelin BMP co-receptor |
|
| chr4_-_61259997 Show fit | 22.94 |
ENSMUST00000071005.9
ENSMUST00000075206.12 |
major urinary protein 14 |
|
| chr4_-_61259801 Show fit | 22.49 |
ENSMUST00000125461.8
|
major urinary protein 14 |
|
| chr6_-_141892517 Show fit | 18.79 |
ENSMUST00000168119.8
|
solute carrier organic anion transporter family, member 1a1 |
|
| chr3_+_130411294 Show fit | 18.10 |
ENSMUST00000163620.8
|
ethanolamine phosphate phospholyase |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 53.6 | GO:0035634 | response to stilbenoid(GO:0035634) |
| 3.2 | 38.1 | GO:0071394 | cellular response to testosterone stimulus(GO:0071394) |
| 1.5 | 22.7 | GO:0015747 | urate transport(GO:0015747) |
| 0.0 | 21.1 | GO:0051321 | meiotic cell cycle(GO:0051321) |
| 4.5 | 18.0 | GO:0015851 | nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855) |
| 0.3 | 12.1 | GO:0000132 | establishment of mitotic spindle orientation(GO:0000132) |
| 0.8 | 7.3 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.1 | 5.8 | GO:0046426 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
| 0.1 | 3.4 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.6 | 3.2 | GO:0002225 | positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 58.6 | GO:0005615 | extracellular space(GO:0005615) |
| 0.1 | 36.8 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.1 | 34.8 | GO:0045177 | apical part of cell(GO:0045177) |
| 0.2 | 31.6 | GO:0000800 | lateral element(GO:0000800) |
| 0.0 | 15.5 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.2 | 2.7 | GO:0036156 | inner dynein arm(GO:0036156) |
| 0.1 | 2.5 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
| 0.0 | 2.1 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.0 | 1.6 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 1.0 | GO:0016528 | sarcoplasm(GO:0016528) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 12.7 | 38.1 | GO:0005009 | insulin-activated receptor activity(GO:0005009) |
| 0.3 | 36.2 | GO:0005550 | pheromone binding(GO:0005550) |
| 0.8 | 31.8 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.2 | 30.4 | GO:0020037 | heme binding(GO:0020037) |
| 2.3 | 22.7 | GO:0015562 | efflux transmembrane transporter activity(GO:0015562) |
| 0.4 | 18.6 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
| 6.0 | 18.1 | GO:0016838 | carbon-oxygen lyase activity, acting on phosphates(GO:0016838) |
| 3.6 | 18.0 | GO:0005345 | purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254) |
| 1.0 | 7.3 | GO:0042328 | heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) |
| 0.0 | 5.8 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.5 | PID NOTCH PATHWAY | Notch signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 18.0 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.2 | 7.3 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.2 | 4.1 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.2 | 2.5 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 0.1 | 1.6 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.0 | 1.0 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |