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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Nr2e1

Z-value: 1.84

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Transcription factors associated with Nr2e1

Gene Symbol Gene ID Gene Info
Nr2e1
ENSMUSG00000019803.12 Nr2e1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr2e1mm39_v1_chr10_-_42459624_42459635-0.123.1e-01Click!

Activity profile of Nr2e1 motif

Sorted Z-values of Nr2e1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr2e1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_-_60457902 38.06 ENSMUST00000084548.11
ENSMUST00000103012.10
ENSMUST00000107499.4
Mup1
major urinary protein 1
chr4_-_62005498 34.84 ENSMUST00000107488.4
ENSMUST00000107472.8
ENSMUST00000084531.11
Mup3
major urinary protein 3
chr4_-_60777462 30.91 ENSMUST00000211875.2
Mup22
major urinary protein 22
chr4_-_61437704 29.88 ENSMUST00000095051.6
ENSMUST00000107483.8
Mup16
major urinary protein 16
chr4_-_60697274 27.04 ENSMUST00000117932.2
Mup12
major urinary protein 12
chr3_+_96432479 25.55 ENSMUST00000049208.11
Hjv
hemojuvelin BMP co-receptor
chr4_-_61259997 22.94 ENSMUST00000071005.9
ENSMUST00000075206.12
Mup14
major urinary protein 14
chr4_-_61259801 22.49 ENSMUST00000125461.8
Mup14
major urinary protein 14
chr6_-_141892517 18.79 ENSMUST00000168119.8
Slco1a1
solute carrier organic anion transporter family, member 1a1
chr3_+_130411294 18.10 ENSMUST00000163620.8
Etnppl
ethanolamine phosphate phospholyase
chr9_-_71070506 18.05 ENSMUST00000074465.9
Aqp9
aquaporin 9
chr4_-_62069046 17.74 ENSMUST00000077719.4
Mup21
major urinary protein 21
chr5_-_87288177 16.96 ENSMUST00000067790.7
Ugt2b5
UDP glucuronosyltransferase 2 family, polypeptide B5
chr17_+_32904629 15.48 ENSMUST00000008801.7
Cyp4f15
cytochrome P450, family 4, subfamily f, polypeptide 15
chr17_+_32904601 14.94 ENSMUST00000168171.8
Cyp4f15
cytochrome P450, family 4, subfamily f, polypeptide 15
chr5_-_87054796 14.84 ENSMUST00000031181.16
ENSMUST00000113333.2
Ugt2b34
UDP glucuronosyltransferase 2 family, polypeptide B34
chr13_+_24023428 13.59 ENSMUST00000091698.12
ENSMUST00000110422.3
ENSMUST00000166467.9
Slc17a3
solute carrier family 17 (sodium phosphate), member 3
chr7_+_114367971 12.11 ENSMUST00000117543.3
ENSMUST00000151464.2
Insc
INSC spindle orientation adaptor protein
chr13_+_24023386 9.14 ENSMUST00000039721.14
Slc17a3
solute carrier family 17 (sodium phosphate), member 3
chr12_+_86781141 8.96 ENSMUST00000223308.2
Lrrc74a
leucine rich repeat containing 74A
chr12_+_86781154 8.07 ENSMUST00000095527.6
Lrrc74a
leucine rich repeat containing 74A
chr19_-_11261177 6.19 ENSMUST00000186937.7
ENSMUST00000067673.13
Ms4a5
membrane-spanning 4-domains, subfamily A, member 5
chr14_-_33737131 5.99 ENSMUST00000227795.2
Gm30083
predicted gene, 30083
chr4_+_60003438 5.85 ENSMUST00000107517.8
ENSMUST00000107520.2
Mup6
major urinary protein 6
chr14_+_28740162 5.76 ENSMUST00000055662.4
Lrtm1
leucine-rich repeats and transmembrane domains 1
chr8_+_71156071 5.42 ENSMUST00000212436.2
Iqcn
IQ motif containing N
chr18_-_60881405 4.89 ENSMUST00000237070.2
Ndst1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr1_-_75196496 4.13 ENSMUST00000186758.7
Tuba4a
tubulin, alpha 4A
chr14_+_33775423 3.87 ENSMUST00000058725.5
Antxrl
anthrax toxin receptor-like
chrX_+_30080456 3.79 ENSMUST00000177917.2
Gm14632
predicted gene 14632
chrX_-_30540953 3.79 ENSMUST00000177566.2
Gm10487
predicted gene 10487
chrX_+_34669447 3.75 ENSMUST00000169396.3
Gm14819
predicted gene 14819
chrX_-_27378797 3.75 ENSMUST00000178745.2
Gm10230
predicted gene 10230
chrX_-_28386687 3.75 ENSMUST00000178966.2
Gm10147
predicted gene 10147
chr14_+_33739013 3.59 ENSMUST00000226499.2
Gm5460
predicted gene 5460
chrX_-_27725713 3.55 ENSMUST00000178152.2
Gm10058
predicted gene 10058
chrX_-_28733497 3.55 ENSMUST00000178672.2
Gm10096
predicted gene 10096
chr17_+_48037758 3.25 ENSMUST00000024782.12
ENSMUST00000144955.2
Pgc
progastricsin (pepsinogen C)
chrY_-_79161056 3.22 ENSMUST00000179922.2
Gm20917
predicted gene, 20917
chrY_-_78847812 3.18 ENSMUST00000180324.2
Gm20806
predicted gene, 20806
chr14_+_33775115 3.14 ENSMUST00000227979.2
Antxrl
anthrax toxin receptor-like
chrY_+_21166083 3.13 ENSMUST00000178234.2
Gm20909
predicted gene, 20909
chrY_-_53413354 3.13 ENSMUST00000179137.2
Gm20747
predicted gene, 20747
chrY_+_24411927 3.09 ENSMUST00000179663.2
Gm20809
predicted gene, 20809
chrY_-_84574663 3.08 ENSMUST00000179523.2
Gm21394
predicted gene, 21394
chrY_-_66751879 3.06 ENSMUST00000178761.2
Gm20852
predicted gene, 20852
chrY_-_85540787 3.01 ENSMUST00000178889.2
Gm20854
predicted gene, 20854
chrY_-_67057835 2.91 ENSMUST00000179136.2
Ssty2
spermiogenesis specific transcript on the Y 2
chrX_-_24639814 2.91 ENSMUST00000178986.2
Gm5935
predicted gene 5935
chrY_-_77972959 2.85 ENSMUST00000178900.2
Gm20867
predicted gene, 20867
chrY_+_68550741 2.83 ENSMUST00000177765.2
Gm20816
predicted gene, 20816
chr4_-_35845204 2.80 ENSMUST00000164772.8
ENSMUST00000065173.9
Lingo2
leucine rich repeat and Ig domain containing 2
chrY_-_65214536 2.79 ENSMUST00000177663.2
Gm20924
predicted gene, 20924
chrX_-_26004758 2.77 ENSMUST00000168002.3
Gm5168
predicted gene 5168
chrY_-_70283393 2.76 ENSMUST00000180179.2
Gm21118
predicted gene, 21118
chr14_+_26414422 2.75 ENSMUST00000022433.12
Dnah12
dynein, axonemal, heavy chain 12
chrX_-_105528972 2.65 ENSMUST00000140707.2
Fndc3c1
fibronectin type III domain containing 3C1
chr4_+_135455427 2.57 ENSMUST00000102546.4
Il22ra1
interleukin 22 receptor, alpha 1
chr7_-_80055168 2.55 ENSMUST00000107362.10
ENSMUST00000135306.3
Furin
furin (paired basic amino acid cleaving enzyme)
chrY_+_9783380 2.50 ENSMUST00000180352.2
Gm20821
predicted gene, 20821
chr3_-_24837772 2.48 ENSMUST00000203414.2
Naaladl2
N-acetylated alpha-linked acidic dipeptidase-like 2
chrY_-_9345654 2.42 ENSMUST00000179590.2
Gm21812
predicted gene, 21812
chr11_-_99482165 2.39 ENSMUST00000104930.2
Krtap1-3
keratin associated protein 1-3
chr18_-_60881679 2.38 ENSMUST00000237783.2
Ndst1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr4_-_59960659 2.35 ENSMUST00000075973.3
Mup4
major urinary protein 4
chr5_-_123185073 2.22 ENSMUST00000031437.14
Morn3
MORN repeat containing 3
chr2_-_85632888 2.22 ENSMUST00000217410.3
ENSMUST00000216425.3
Olfr1016
olfactory receptor 1016
chrX_-_142610371 2.06 ENSMUST00000087316.6
Capn6
calpain 6
chrY_-_9132561 2.05 ENSMUST00000171947.3
Gm21292
predicted gene, 21292
chrY_+_21242966 2.04 ENSMUST00000179095.2
Gm20865
predicted gene, 20865
chr2_+_51517523 1.96 ENSMUST00000070028.3
Tas2r134
taste receptor, type 2, member 134
chr7_+_131144596 1.92 ENSMUST00000046093.6
Hmx3
H6 homeobox 3
chrY_-_6917117 1.81 ENSMUST00000178016.2
Gm20830
predicted gene, 20830
chrX_-_105528503 1.81 ENSMUST00000138724.8
ENSMUST00000149331.2
Fndc3c1
fibronectin type III domain containing 3C1
chrY_-_9200643 1.79 ENSMUST00000179595.2
Gm21721
predicted gene, 21721
chr5_+_16996808 1.77 ENSMUST00000211738.2
Gm28710
predicted gene 28710
chrY_+_5727496 1.73 ENSMUST00000180372.2
Gm20914
predicted gene, 20914
chrY_-_7636973 1.65 ENSMUST00000179256.2
Gm20826
predicted gene, 20826
chr12_-_75596441 1.63 ENSMUST00000218716.2
Ppp2r5e
protein phosphatase 2, regulatory subunit B', epsilon
chr11_-_58521327 1.54 ENSMUST00000214132.2
Olfr323
olfactory receptor 323
chrY_-_7167777 1.52 ENSMUST00000178447.2
Gm21244
predicted gene, 21244
chr6_+_42377172 1.47 ENSMUST00000057398.4
Tas2r143
taste receptor, type 2, member 143
chr5_-_123185029 1.44 ENSMUST00000045843.15
Morn3
MORN repeat containing 3
chrX_+_48552803 1.30 ENSMUST00000130558.8
Arhgap36
Rho GTPase activating protein 36
chr4_-_119272640 1.15 ENSMUST00000238293.2
Ccdc30
coiled-coil domain containing 30
chr3_+_14643669 1.02 ENSMUST00000029069.13
ENSMUST00000165922.3
E2f5
E2F transcription factor 5
chrY_-_15883245 0.96 ENSMUST00000165756.2
Gm20822
predicted gene, 20822
chrY_-_10323434 0.91 ENSMUST00000179558.2
Gm20834
predicted gene, 20834
chrY_-_11197848 0.81 ENSMUST00000170889.2
Gm20828
predicted gene, 20828
chrY_+_12383184 0.76 ENSMUST00000179220.2
Gm20812
predicted gene, 20812
chr8_-_62355690 0.64 ENSMUST00000121785.9
ENSMUST00000034057.14
Palld
palladin, cytoskeletal associated protein
chr4_-_119272667 0.60 ENSMUST00000238609.2
Ccdc30
coiled-coil domain containing 30
chr2_-_111820618 0.56 ENSMUST00000216948.2
ENSMUST00000214935.2
ENSMUST00000217452.2
ENSMUST00000215045.2
Olfr1309
olfactory receptor 1309
chr18_+_77369654 0.31 ENSMUST00000096547.11
ENSMUST00000148341.9
ENSMUST00000123410.9
Loxhd1
lipoxygenase homology domains 1
chr4_-_96029375 0.29 ENSMUST00000097972.5
Cyp2j12
cytochrome P450, family 2, subfamily j, polypeptide 12
chr4_+_28813125 0.21 ENSMUST00000080934.11
ENSMUST00000029964.12
Epha7
Eph receptor A7
chr12_+_111132779 0.18 ENSMUST00000117269.8
Traf3
TNF receptor-associated factor 3
chr7_+_104713682 0.16 ENSMUST00000213622.2
Olfr678
olfactory receptor 678
chrX_-_133012457 0.12 ENSMUST00000159259.3
ENSMUST00000113275.10
Nox1
NADPH oxidase 1
chr2_-_22930149 0.10 ENSMUST00000091394.13
ENSMUST00000093171.13
Abi1
abl interactor 1
chr2_-_111251294 0.06 ENSMUST00000099617.2
Olfr1286
olfactory receptor 1286
chr8_+_36956345 0.03 ENSMUST00000171777.2
Trmt9b
tRNA methyltransferase 9B

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 18.0 GO:0015851 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
3.2 38.1 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
1.7 53.6 GO:0035634 response to stilbenoid(GO:0035634)
1.5 22.7 GO:0015747 urate transport(GO:0015747)
0.8 7.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.6 3.2 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.6 2.5 GO:0090472 dibasic protein processing(GO:0090472)
0.3 12.1 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.2 2.7 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 3.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 5.8 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 21.1 GO:0051321 meiotic cell cycle(GO:0051321)
0.0 2.6 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.1 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.6 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 1.9 GO:0060135 maternal process involved in female pregnancy(GO:0060135)
0.0 2.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 2.1 GO:0001578 microtubule bundle formation(GO:0001578)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 31.6 GO:0000800 lateral element(GO:0000800)
0.2 2.7 GO:0036156 inner dynein arm(GO:0036156)
0.1 2.5 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 36.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 34.8 GO:0045177 apical part of cell(GO:0045177)
0.0 1.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 2.1 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 15.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 58.6 GO:0005615 extracellular space(GO:0005615)
0.0 0.6 GO:0002102 podosome(GO:0002102)
0.0 1.0 GO:0016528 sarcoplasm(GO:0016528)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
12.7 38.1 GO:0005009 insulin-activated receptor activity(GO:0005009)
6.0 18.1 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
3.6 18.0 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
2.3 22.7 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
1.0 7.3 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.9 2.6 GO:0042015 interleukin-20 binding(GO:0042015)
0.8 31.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.4 18.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.3 36.2 GO:0005550 pheromone binding(GO:0005550)
0.2 30.4 GO:0020037 heme binding(GO:0020037)
0.2 3.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 2.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 3.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 2.7 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 2.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 5.8 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 4.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 1.6 GO:0019888 protein phosphatase regulator activity(GO:0019888)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.5 PID NOTCH PATHWAY Notch signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 18.0 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 4.1 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.2 2.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 7.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.6 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.0 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1