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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Nr3c2

Z-value: 0.45

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Transcription factors associated with Nr3c2

Gene Symbol Gene ID Gene Info
Nr3c2
ENSMUSG00000031618.14 Nr3c2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr3c2mm39_v1_chr8_+_77628916_776291040.152.2e-01Click!

Activity profile of Nr3c2 motif

Sorted Z-values of Nr3c2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr3c2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr14_+_70768257 2.57 ENSMUST00000047331.8
Lgi3
leucine-rich repeat LGI family, member 3
chr14_+_70768289 2.29 ENSMUST00000226548.2
Lgi3
leucine-rich repeat LGI family, member 3
chr1_-_74974707 2.25 ENSMUST00000094844.4
Cfap65
cilia and flagella associated protein 65
chr10_-_117118226 1.51 ENSMUST00000092163.9
Lyz2
lysozyme 2
chr15_+_102011415 1.48 ENSMUST00000046144.10
Tns2
tensin 2
chr15_+_102011352 1.46 ENSMUST00000169627.9
Tns2
tensin 2
chr15_+_102010632 1.33 ENSMUST00000229592.2
Tns2
tensin 2
chr6_-_69584812 1.17 ENSMUST00000103359.3
Igkv4-55
immunoglobulin kappa variable 4-55
chr14_+_14159978 1.10 ENSMUST00000137133.2
ENSMUST00000036070.15
ENSMUST00000121887.8
Fam107a
family with sequence similarity 107, member A
chr5_+_112436599 1.10 ENSMUST00000151947.3
Tpst2
protein-tyrosine sulfotransferase 2
chr11_+_96822213 0.98 ENSMUST00000107633.2
Prr15l
proline rich 15-like
chr3_-_95811993 0.92 ENSMUST00000147962.3
ENSMUST00000036181.15
Car14
carbonic anhydrase 14
chr11_+_68989763 0.89 ENSMUST00000021271.14
Per1
period circadian clock 1
chr11_+_98277276 0.87 ENSMUST00000041301.8
Pnmt
phenylethanolamine-N-methyltransferase
chr6_-_69282389 0.81 ENSMUST00000103350.3
Igkv4-68
immunoglobulin kappa variable 4-68
chr5_-_135494775 0.79 ENSMUST00000212301.2
Hip1
huntingtin interacting protein 1
chr6_+_34840057 0.79 ENSMUST00000074949.4
Tmem140
transmembrane protein 140
chr1_-_157084252 0.75 ENSMUST00000134543.8
Rasal2
RAS protein activator like 2
chr6_+_34840151 0.68 ENSMUST00000202010.2
Tmem140
transmembrane protein 140
chr6_-_69394425 0.68 ENSMUST00000199160.2
Igkv4-61
immunoglobulin kappa chain variable 4-61
chr6_-_69245427 0.62 ENSMUST00000103348.3
Igkv4-70
immunoglobulin kappa chain variable 4-70
chr7_-_25089522 0.61 ENSMUST00000054301.14
Lipe
lipase, hormone sensitive
chr10_+_26698556 0.57 ENSMUST00000135866.2
Arhgap18
Rho GTPase activating protein 18
chr14_-_68771138 0.55 ENSMUST00000022640.8
Adam7
a disintegrin and metallopeptidase domain 7
chr6_-_69678271 0.55 ENSMUST00000103363.2
Igkv4-50
immunoglobulin kappa variable 4-50
chr2_-_164435508 0.54 ENSMUST00000103100.2
Eppin
epididymal peptidase inhibitor
chr9_-_75504926 0.43 ENSMUST00000164100.2
Tmod2
tropomodulin 2
chr6_-_69377328 0.41 ENSMUST00000198345.2
Igkv4-62
immunoglobulin kappa variable 4-62
chr11_-_71092282 0.36 ENSMUST00000108515.9
Nlrp1b
NLR family, pyrin domain containing 1B
chr16_-_95993420 0.36 ENSMUST00000113804.8
ENSMUST00000054855.14
Lca5l
Leber congenital amaurosis 5-like
chr6_-_69020489 0.34 ENSMUST00000103342.4
Igkv4-79
immunoglobulin kappa variable 4-79
chr5_-_31854942 0.34 ENSMUST00000031018.10
Rbks
ribokinase
chr6_-_69037208 0.34 ENSMUST00000103343.4
Igkv4-78
immunoglobulin kappa variable 4-78
chr8_+_94905710 0.33 ENSMUST00000034215.8
ENSMUST00000212291.2
ENSMUST00000211807.2
Mt1
metallothionein 1
chr5_+_146428173 0.32 ENSMUST00000110611.8
ENSMUST00000198912.2
Gm6370
predicted gene 6370
chr6_-_69204417 0.29 ENSMUST00000103346.3
Igkv4-72
immunoglobulin kappa chain variable 4-72
chr15_-_85705935 0.28 ENSMUST00000064370.6
Pkdrej
polycystin (PKD) family receptor for egg jelly
chr5_-_146107531 0.28 ENSMUST00000174320.2
Gm6309
predicted gene 6309
chr5_+_146439209 0.27 ENSMUST00000110598.3
4930449I24Rik
RIKEN cDNA 4930449I24 gene
chr6_-_69377081 0.27 ENSMUST00000177795.2
Igkv4-62
immunoglobulin kappa variable 4-62
chr5_+_146474457 0.26 ENSMUST00000199142.5
ENSMUST00000110597.4
ENSMUST00000110599.9
Gm3409
predicted gene 3409
chr10_+_21869776 0.25 ENSMUST00000092673.11
Sgk1
serum/glucocorticoid regulated kinase 1
chr5_+_146450933 0.25 ENSMUST00000200228.5
ENSMUST00000036715.16
ENSMUST00000077133.7
Gm3402
predicted gene 3402
chrX_-_126644166 0.24 ENSMUST00000052500.6
Cldn34c4
claudin 34C4
chr16_+_38167352 0.21 ENSMUST00000050273.9
ENSMUST00000120495.2
ENSMUST00000119704.2
Cox17
Gm21987
cytochrome c oxidase assembly protein 17, copper chaperone
predicted gene 21987
chr5_+_146492946 0.20 ENSMUST00000179214.8
ENSMUST00000110595.3
Gm3415
predicted gene 3415
chr11_-_71092124 0.20 ENSMUST00000108514.10
Nlrp1b
NLR family, pyrin domain containing 1B
chr14_+_35816874 0.18 ENSMUST00000226305.2
4930474N05Rik
RIKEN cDNA 4930474N05 gene
chr5_-_146097347 0.17 ENSMUST00000199463.2
Gm5565
predicted gene 5565
chr9_+_123195986 0.16 ENSMUST00000038863.9
ENSMUST00000216843.2
Lars2
leucyl-tRNA synthetase, mitochondrial
chr5_+_146418775 0.16 ENSMUST00000179032.3
Gm6408
predicted gene 6408
chr6_-_126512375 0.15 ENSMUST00000060972.5
Kcna5
potassium voltage-gated channel, shaker-related subfamily, member 5
chr5_+_31855009 0.12 ENSMUST00000201352.4
ENSMUST00000202815.4
Babam2
BRISC and BRCA1 A complex member 2
chr6_+_52691204 0.10 ENSMUST00000138040.8
ENSMUST00000129660.2
Tax1bp1
Tax1 (human T cell leukemia virus type I) binding protein 1
chr8_-_25730878 0.08 ENSMUST00000210488.2
ENSMUST00000210933.2
Tacc1
transforming, acidic coiled-coil containing protein 1
chr7_+_118199375 0.07 ENSMUST00000121744.9
Tmc5
transmembrane channel-like gene family 5
chrX_+_101846569 0.04 ENSMUST00000118218.8
Dmrtc1c1
DMRT-like family C1c1
chrX_-_101898222 0.04 ENSMUST00000120314.8
Dmrtc1c2
DMRT-like family C1c2
chr6_+_125297596 0.04 ENSMUST00000176655.8
ENSMUST00000176110.8
Scnn1a
sodium channel, nonvoltage-gated 1 alpha
chr17_-_23531402 0.04 ENSMUST00000168033.3
Vmn2r114
vomeronasal 2, receptor 114
chr6_-_69220672 0.03 ENSMUST00000196201.2
Igkv4-71
immunoglobulin kappa chain variable 4-71
chr14_+_44822935 0.03 ENSMUST00000178759.2
Gm8247
predicted gene 8247
chr11_+_50905063 0.02 ENSMUST00000217480.2
ENSMUST00000215409.2
Olfr54
olfactory receptor 54
chr11_+_101339233 0.01 ENSMUST00000010502.13
Ifi35
interferon-induced protein 35
chr14_-_42461286 0.01 ENSMUST00000163102.2
Gm3633
predicted gene 3633
chr4_-_9643636 0.01 ENSMUST00000108333.8
ENSMUST00000108334.8
ENSMUST00000108335.8
ENSMUST00000152526.8
ENSMUST00000103004.10
Asph
aspartate-beta-hydroxylase
chr10_-_14593935 0.01 ENSMUST00000020016.5
Gje1
gap junction protein, epsilon 1
chr14_-_42116736 0.00 ENSMUST00000100698.4
Gm9611
predicted gene 9611

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.2 0.2 GO:1904959 regulation of cytochrome-c oxidase activity(GO:1904959)
0.2 0.8 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.2 4.3 GO:0014850 response to muscle activity(GO:0014850)
0.2 0.9 GO:0042414 epinephrine metabolic process(GO:0042414)
0.2 0.6 GO:0046340 termination of RNA polymerase I transcription(GO:0006363) diacylglycerol catabolic process(GO:0046340)
0.1 0.9 GO:0097167 circadian regulation of translation(GO:0097167)
0.1 0.6 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.1 0.3 GO:0006014 D-ribose metabolic process(GO:0006014)
0.1 1.5 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.9 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.3 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1 0.2 GO:0006429 leucyl-tRNA aminoacylation(GO:0006429)
0.0 0.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 5.5 GO:0002377 immunoglobulin production(GO:0002377)
0.0 5.1 GO:0017157 regulation of exocytosis(GO:0017157)
0.0 0.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:0098914 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043) membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 0.8 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.1 0.6 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.9 GO:0043196 varicosity(GO:0043196)
0.0 4.9 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.6 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 1.5 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.8 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.2 GO:0004823 leucine-tRNA ligase activity(GO:0004823)
0.1 0.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.2 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.1 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 4.3 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.9 GO:0070888 E-box binding(GO:0070888)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 4.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.9 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression