Project

PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

Navigation
Downloads

Results for Nr4a2

Z-value: 0.77

Motif logo

logo of

Transcription factors associated with Nr4a2

Gene Symbol Gene ID Gene Info
Nr4a2
ENSMUSG00000026826.14 Nr4a2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr4a2mm39_v1_chr2_-_57004933_570050500.161.9e-01Click!

Activity profile of Nr4a2 motif

Sorted Z-values of Nr4a2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr4a2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr3_-_144680801 9.82 ENSMUST00000029923.10
ENSMUST00000238960.2
Clca4a
chloride channel accessory 4A
chr12_+_31488208 9.08 ENSMUST00000001254.6
Slc26a3
solute carrier family 26, member 3
chr3_-_144638284 7.89 ENSMUST00000098549.4
Clca4b
chloride channel accessory 4B
chr11_+_70548022 6.08 ENSMUST00000157027.8
ENSMUST00000072841.12
ENSMUST00000108548.8
ENSMUST00000126241.8
Eno3
enolase 3, beta muscle
chr13_+_74269554 5.88 ENSMUST00000036208.7
ENSMUST00000225423.2
ENSMUST00000221703.2
Slc9a3
solute carrier family 9 (sodium/hydrogen exchanger), member 3
chr2_-_163239865 4.90 ENSMUST00000017961.11
ENSMUST00000109425.3
Jph2
junctophilin 2
chr12_-_76842263 4.61 ENSMUST00000082431.6
Gpx2
glutathione peroxidase 2
chr3_+_122688721 3.81 ENSMUST00000023820.6
Fabp2
fatty acid binding protein 2, intestinal
chr2_+_132623198 3.62 ENSMUST00000028826.4
Chgb
chromogranin B
chr8_-_46664321 3.48 ENSMUST00000034049.5
Slc25a4
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
chr11_+_70548622 3.47 ENSMUST00000170716.8
Eno3
enolase 3, beta muscle
chr8_+_105573693 3.18 ENSMUST00000055052.6
Ces2c
carboxylesterase 2C
chr1_-_190950129 3.15 ENSMUST00000195117.2
Atf3
activating transcription factor 3
chr11_-_69838971 2.87 ENSMUST00000179298.3
ENSMUST00000018710.13
ENSMUST00000135437.3
ENSMUST00000141837.9
ENSMUST00000142500.8
Slc2a4
solute carrier family 2 (facilitated glucose transporter), member 4
chr11_+_70548513 2.70 ENSMUST00000134087.8
Eno3
enolase 3, beta muscle
chr1_+_57884693 2.66 ENSMUST00000169772.3
Spats2l
spermatogenesis associated, serine-rich 2-like
chr1_+_83094481 2.61 ENSMUST00000027351.13
ENSMUST00000113437.9
ENSMUST00000186832.2
Ccl20
chemokine (C-C motif) ligand 20
chr6_-_124791259 2.43 ENSMUST00000172132.10
ENSMUST00000239432.2
Tpi1
triosephosphate isomerase 1
chr15_+_35296237 2.30 ENSMUST00000022952.6
Osr2
odd-skipped related 2
chr6_-_3487369 2.28 ENSMUST00000201607.4
Hepacam2
HEPACAM family member 2
chr1_+_87501721 2.20 ENSMUST00000166259.8
ENSMUST00000172222.8
ENSMUST00000163606.8
Neu2
neuraminidase 2
chr1_-_167221344 2.16 ENSMUST00000028005.3
Mgst3
microsomal glutathione S-transferase 3
chr13_+_118851214 2.06 ENSMUST00000022246.9
Fgf10
fibroblast growth factor 10
chr7_-_89176294 1.87 ENSMUST00000207932.2
Prss23
protease, serine 23
chr4_-_141351110 1.74 ENSMUST00000038661.8
Slc25a34
solute carrier family 25, member 34
chr13_-_98152768 1.68 ENSMUST00000238746.2
Arhgef28
Rho guanine nucleotide exchange factor (GEF) 28
chr16_+_21644692 1.66 ENSMUST00000232240.2
Map3k13
mitogen-activated protein kinase kinase kinase 13
chr2_-_13496624 1.62 ENSMUST00000091436.7
Cubn
cubilin (intrinsic factor-cobalamin receptor)
chr1_-_63215812 1.56 ENSMUST00000185847.2
ENSMUST00000185732.7
ENSMUST00000188370.7
ENSMUST00000168099.9
Ndufs1
NADH:ubiquinone oxidoreductase core subunit S1
chr10_-_42354276 1.55 ENSMUST00000151747.8
Afg1l
AFG1 like ATPase
chr10_-_42354482 1.42 ENSMUST00000041024.15
Afg1l
AFG1 like ATPase
chr15_-_98505508 1.41 ENSMUST00000096224.6
Adcy6
adenylate cyclase 6
chr9_+_118335294 1.38 ENSMUST00000084820.6
Golga4
golgi autoantigen, golgin subfamily a, 4
chr18_+_86729184 1.36 ENSMUST00000068423.10
Cbln2
cerebellin 2 precursor protein
chr7_-_141009264 1.34 ENSMUST00000164387.2
ENSMUST00000137488.2
ENSMUST00000084436.10
Cend1
cell cycle exit and neuronal differentiation 1
chr15_+_25940859 1.31 ENSMUST00000226750.2
Retreg1
reticulophagy regulator 1
chr1_-_123972900 1.31 ENSMUST00000112603.4
Dpp10
dipeptidylpeptidase 10
chr3_+_89344006 1.30 ENSMUST00000038942.10
ENSMUST00000130858.8
ENSMUST00000146630.8
ENSMUST00000145753.2
Pbxip1
pre B cell leukemia transcription factor interacting protein 1
chr15_-_76113692 1.30 ENSMUST00000074834.12
Plec
plectin
chr1_-_63215952 1.24 ENSMUST00000185412.7
ENSMUST00000027111.15
ENSMUST00000189664.2
Ndufs1
NADH:ubiquinone oxidoreductase core subunit S1
chr2_-_129541753 1.18 ENSMUST00000028883.12
Pdyn
prodynorphin
chr10_+_98943999 1.18 ENSMUST00000161240.4
Galnt4
polypeptide N-acetylgalactosaminyltransferase 4
chr5_-_121665249 1.15 ENSMUST00000152270.8
Mapkapk5
MAP kinase-activated protein kinase 5
chr1_-_87501548 1.15 ENSMUST00000068681.12
Ngef
neuronal guanine nucleotide exchange factor
chr11_-_59029996 1.14 ENSMUST00000219084.3
Obscn
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr6_-_138399896 1.11 ENSMUST00000161450.8
ENSMUST00000163024.8
ENSMUST00000162185.8
Lmo3
LIM domain only 3
chr7_+_120234399 1.10 ENSMUST00000033176.7
ENSMUST00000208400.2
Uqcrc2
ubiquinol cytochrome c reductase core protein 2
chr15_+_102875229 1.10 ENSMUST00000001699.8
Hoxc10
homeobox C10
chr19_-_32038838 1.05 ENSMUST00000096119.5
Asah2
N-acylsphingosine amidohydrolase 2
chr11_+_121593582 1.04 ENSMUST00000125580.2
Metrnl
meteorin, glial cell differentiation regulator-like
chr4_+_99812912 1.02 ENSMUST00000102783.5
Pgm1
phosphoglucomutase 1
chr19_+_11724913 1.00 ENSMUST00000025585.4
Cblif
cobalamin binding intrinsic factor
chr10_-_23226684 1.00 ENSMUST00000220299.2
Eya4
EYA transcriptional coactivator and phosphatase 4
chr11_+_4207557 0.91 ENSMUST00000066283.12
Lif
leukemia inhibitory factor
chr15_+_25940781 0.87 ENSMUST00000227275.2
Retreg1
reticulophagy regulator 1
chr5_-_66309244 0.85 ENSMUST00000167950.8
Rbm47
RNA binding motif protein 47
chr2_-_120394288 0.85 ENSMUST00000055241.13
ENSMUST00000135625.8
Zfp106
zinc finger protein 106
chr7_+_140500848 0.81 ENSMUST00000184560.2
Nlrp6
NLR family, pyrin domain containing 6
chr8_-_65186565 0.80 ENSMUST00000141021.2
Msmo1
methylsterol monoxygenase 1
chr5_+_30437579 0.79 ENSMUST00000145167.9
Selenoi
selenoprotein I
chrX_-_16683578 0.76 ENSMUST00000040820.13
Maob
monoamine oxidase B
chr7_-_141009346 0.73 ENSMUST00000124444.2
Cend1
cell cycle exit and neuronal differentiation 1
chr7_+_140500808 0.71 ENSMUST00000106045.8
ENSMUST00000183845.8
Nlrp6
NLR family, pyrin domain containing 6
chr5_-_67256578 0.71 ENSMUST00000012664.11
Phox2b
paired-like homeobox 2b
chr15_+_25940931 0.69 ENSMUST00000110438.3
Retreg1
reticulophagy regulator 1
chr10_-_20600442 0.68 ENSMUST00000170265.8
Pde7b
phosphodiesterase 7B
chr19_-_40371016 0.65 ENSMUST00000225766.3
Sorbs1
sorbin and SH3 domain containing 1
chr5_+_150183201 0.61 ENSMUST00000087204.9
Fry
FRY microtubule binding protein
chr6_+_96090127 0.60 ENSMUST00000122120.8
Tafa1
TAFA chemokine like family member 1
chr10_-_20600797 0.59 ENSMUST00000020165.14
Pde7b
phosphodiesterase 7B
chr7_+_4122523 0.57 ENSMUST00000119661.8
ENSMUST00000129423.8
Ttyh1
tweety family member 1
chr10_+_110756031 0.56 ENSMUST00000220409.2
ENSMUST00000219502.2
Csrp2
cysteine and glycine-rich protein 2
chr10_+_27950809 0.56 ENSMUST00000166468.2
ENSMUST00000218359.2
ENSMUST00000218276.2
Ptprk
protein tyrosine phosphatase, receptor type, K
chr2_+_121125918 0.54 ENSMUST00000110639.8
Map1a
microtubule-associated protein 1 A
chr13_+_93440265 0.53 ENSMUST00000109494.8
Homer1
homer scaffolding protein 1
chr15_+_25940912 0.51 ENSMUST00000226438.2
Retreg1
reticulophagy regulator 1
chr2_+_105499233 0.49 ENSMUST00000111086.11
ENSMUST00000111087.10
Pax6
paired box 6
chr3_-_87934772 0.48 ENSMUST00000005014.9
Hapln2
hyaluronan and proteoglycan link protein 2
chr7_+_4122555 0.47 ENSMUST00000079415.12
Ttyh1
tweety family member 1
chr2_+_158636727 0.47 ENSMUST00000029186.14
ENSMUST00000109478.9
ENSMUST00000156893.2
Dhx35
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr1_+_167445815 0.46 ENSMUST00000111380.2
Rxrg
retinoid X receptor gamma
chr9_-_106533279 0.46 ENSMUST00000023959.13
ENSMUST00000201681.2
Grm2
glutamate receptor, metabotropic 2
chr10_-_40178182 0.46 ENSMUST00000099945.6
ENSMUST00000238953.2
ENSMUST00000238969.2
Amd1
S-adenosylmethionine decarboxylase 1
chr2_+_172994841 0.44 ENSMUST00000029017.6
Pck1
phosphoenolpyruvate carboxykinase 1, cytosolic
chr3_-_20329823 0.43 ENSMUST00000011607.6
Cpb1
carboxypeptidase B1 (tissue)
chr18_+_77861656 0.43 ENSMUST00000114748.2
Atp5a1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1
chr11_-_79394904 0.42 ENSMUST00000164465.3
Omg
oligodendrocyte myelin glycoprotein
chrX_-_166638057 0.42 ENSMUST00000238211.2
Frmpd4
FERM and PDZ domain containing 4
chr19_-_40371242 0.42 ENSMUST00000224583.2
Sorbs1
sorbin and SH3 domain containing 1
chr10_+_90665639 0.38 ENSMUST00000179337.9
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr2_-_73741664 0.37 ENSMUST00000111996.8
ENSMUST00000018914.3
Atp5g3
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)
chr16_+_8647959 0.37 ENSMUST00000023150.7
1810013L24Rik
RIKEN cDNA 1810013L24 gene
chr8_-_13544478 0.37 ENSMUST00000033828.7
Gas6
growth arrest specific 6
chr19_-_5168251 0.35 ENSMUST00000113728.8
ENSMUST00000113727.8
ENSMUST00000025798.13
Klc2
kinesin light chain 2
chr2_-_101451383 0.35 ENSMUST00000090513.11
Iftap
intraflagellar transport associated protein
chr3_-_95041246 0.35 ENSMUST00000172572.9
ENSMUST00000173462.3
Scnm1
sodium channel modifier 1
chr2_+_4980923 0.35 ENSMUST00000167607.8
ENSMUST00000115010.9
Ucma
upper zone of growth plate and cartilage matrix associated
chr2_+_4980986 0.29 ENSMUST00000027978.7
ENSMUST00000195688.2
Ucma
upper zone of growth plate and cartilage matrix associated
chr4_+_102617495 0.28 ENSMUST00000072481.12
ENSMUST00000156596.8
ENSMUST00000080728.13
ENSMUST00000106882.9
Sgip1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr2_-_165125519 0.28 ENSMUST00000155289.8
Slc35c2
solute carrier family 35, member C2
chr11_-_24025054 0.27 ENSMUST00000068360.2
A830031A19Rik
RIKEN cDNA A830031A19 gene
chr2_-_26127360 0.27 ENSMUST00000036187.9
Qsox2
quiescin Q6 sulfhydryl oxidase 2
chr10_-_99595498 0.27 ENSMUST00000056085.6
Csl
citrate synthase like
chr7_-_65177444 0.27 ENSMUST00000206228.2
Tjp1
tight junction protein 1
chr10_-_12745109 0.26 ENSMUST00000218635.2
Utrn
utrophin
chr19_+_46140942 0.24 ENSMUST00000026254.14
Gbf1
golgi-specific brefeldin A-resistance factor 1
chr2_+_61423469 0.24 ENSMUST00000112494.2
Tank
TRAF family member-associated Nf-kappa B activator
chr9_+_21914513 0.23 ENSMUST00000215795.2
Prkcsh
protein kinase C substrate 80K-H
chr1_+_63215976 0.23 ENSMUST00000129339.8
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr1_+_63216281 0.21 ENSMUST00000188524.2
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr9_+_21914296 0.20 ENSMUST00000003493.9
Prkcsh
protein kinase C substrate 80K-H
chr15_+_76579960 0.20 ENSMUST00000229679.2
Gpt
glutamic pyruvic transaminase, soluble
chr2_+_128907854 0.20 ENSMUST00000035812.14
Ttl
tubulin tyrosine ligase
chr5_+_63806451 0.19 ENSMUST00000159584.3
Nwd2
NACHT and WD repeat domain containing 2
chr2_+_127180559 0.17 ENSMUST00000059839.9
Astl
astacin-like metalloendopeptidase (M12 family)
chr9_+_21914083 0.17 ENSMUST00000216344.2
Prkcsh
protein kinase C substrate 80K-H
chr7_-_102566717 0.16 ENSMUST00000214160.2
ENSMUST00000215773.2
Olfr571
olfactory receptor 571
chr16_-_20245071 0.16 ENSMUST00000115547.9
ENSMUST00000096199.5
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chrX_-_47602395 0.15 ENSMUST00000114945.9
ENSMUST00000037349.8
Aifm1
apoptosis-inducing factor, mitochondrion-associated 1
chr10_-_93425553 0.15 ENSMUST00000020203.7
Snrpf
small nuclear ribonucleoprotein polypeptide F
chr15_+_25774070 0.13 ENSMUST00000125667.3
Myo10
myosin X
chr9_+_21914334 0.13 ENSMUST00000115331.10
Prkcsh
protein kinase C substrate 80K-H
chr4_-_150998857 0.12 ENSMUST00000105675.8
Park7
Parkinson disease (autosomal recessive, early onset) 7
chr16_-_20245138 0.11 ENSMUST00000079158.13
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr10_-_35587888 0.10 ENSMUST00000080898.4
Amd2
S-adenosylmethionine decarboxylase 2
chr14_+_27598021 0.08 ENSMUST00000211684.2
ENSMUST00000210924.2
Erc2
ELKS/RAB6-interacting/CAST family member 2
chr19_-_45986919 0.07 ENSMUST00000045396.9
Armh3
armadillo-like helical domain containing 3
chr12_+_119356318 0.06 ENSMUST00000221866.2
Macc1
metastasis associated in colon cancer 1
chr4_-_36136463 0.06 ENSMUST00000098151.9
Lingo2
leucine rich repeat and Ig domain containing 2
chr4_+_33081505 0.06 ENSMUST00000147889.2
Gabrr2
gamma-aminobutyric acid (GABA) C receptor, subunit rho 2
chr9_+_98746796 0.05 ENSMUST00000167951.3
Prr23a3
proline rich 23A, member 3
chr16_-_43959993 0.05 ENSMUST00000137557.8
Atp6v1a
ATPase, H+ transporting, lysosomal V1 subunit A
chr2_-_73722874 0.05 ENSMUST00000136958.8
ENSMUST00000112010.9
ENSMUST00000128531.8
ENSMUST00000112017.8
Atf2
activating transcription factor 2
chr17_+_70829050 0.03 ENSMUST00000133717.9
ENSMUST00000148486.8
Dlgap1
DLG associated protein 1
chr2_+_75662806 0.02 ENSMUST00000175646.2
Agps
alkylglycerone phosphate synthase
chr2_-_25911544 0.02 ENSMUST00000136750.3
Ubac1
ubiquitin associated domain containing 1
chr9_-_21996693 0.01 ENSMUST00000179422.8
ENSMUST00000098937.10
ENSMUST00000177967.2
ENSMUST00000180180.8
Ecsit
ECSIT signalling integrator
chr6_+_132832401 0.01 ENSMUST00000032315.3
Tas2r116
taste receptor, type 2, member 116

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.6 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.9 3.5 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.9 2.6 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.8 2.4 GO:0019405 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.8 3.1 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.7 2.1 GO:0060435 bronchiole development(GO:0060435) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.6 4.9 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.6 9.1 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.6 3.0 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.5 2.1 GO:0021941 radial glia guided migration of cerebellar granule cell(GO:0021933) negative regulation of cerebellar granule cell precursor proliferation(GO:0021941)
0.5 5.9 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.5 1.4 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.5 2.3 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.4 3.4 GO:0061709 reticulophagy(GO:0061709)
0.4 0.4 GO:1900141 regulation of oligodendrocyte apoptotic process(GO:1900141) negative regulation of oligodendrocyte apoptotic process(GO:1900142)
0.3 2.2 GO:0009313 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.3 1.6 GO:0015889 cobalamin transport(GO:0015889)
0.2 0.7 GO:0021934 hindbrain tangential cell migration(GO:0021934)
0.2 0.6 GO:0006597 spermine biosynthetic process(GO:0006597)
0.2 1.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.2 0.6 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.2 0.8 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.2 0.9 GO:0043974 histone H3-K27 acetylation(GO:0043974) spongiotrophoblast differentiation(GO:0060708) regulation of histone H3-K27 acetylation(GO:1901674)
0.1 18.8 GO:0006821 chloride transport(GO:0006821)
0.1 0.4 GO:0061402 glycerol biosynthetic process(GO:0006114) positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
0.1 1.1 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 1.7 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 12.2 GO:0006096 glycolytic process(GO:0006096)
0.1 2.9 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.1 1.5 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 1.1 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.1 1.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 3.8 GO:0050892 intestinal absorption(GO:0050892)
0.1 1.1 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.3 GO:0015786 UDP-glucose transport(GO:0015786)
0.1 0.5 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 1.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 1.4 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 1.1 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 2.9 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.6 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.3 GO:0007527 adult somatic muscle development(GO:0007527)
0.0 0.2 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.0 0.4 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.5 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.8 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.7 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.4 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 1.3 GO:1903078 positive regulation of protein localization to plasma membrane(GO:1903078)
0.0 0.9 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.4 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 1.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 2.3 GO:0007098 centrosome cycle(GO:0007098)
0.0 1.4 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.5 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.9 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.2 GO:1902510 regulation of apoptotic DNA fragmentation(GO:1902510)
0.0 0.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.5 GO:0014047 glutamate secretion(GO:0014047)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.9 12.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.4 4.9 GO:0030314 junctional membrane complex(GO:0030314)
0.4 1.1 GO:0032156 septin cytoskeleton(GO:0032156)
0.4 1.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.3 3.8 GO:0045179 apical cortex(GO:0045179)
0.3 1.6 GO:0043202 lysosomal lumen(GO:0043202)
0.3 9.1 GO:0097225 sperm midpiece(GO:0097225)
0.2 1.0 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.2 1.1 GO:0005899 insulin receptor complex(GO:0005899)
0.2 2.9 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.7 GO:0017177 glucosidase II complex(GO:0017177)
0.1 1.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 1.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 1.5 GO:0061702 inflammasome complex(GO:0061702)
0.1 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.2 GO:0060473 cortical granule(GO:0060473)
0.1 2.9 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 3.9 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.4 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 1.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 4.4 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.4 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:0070938 contractile ring(GO:0070938)
0.0 0.6 GO:0016235 aggresome(GO:0016235)
0.0 2.3 GO:0030496 midbody(GO:0030496)
0.0 3.1 GO:0043209 myelin sheath(GO:0043209)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 12.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.6 5.9 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.6 2.9 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.6 17.7 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.5 9.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.4 2.2 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.4 3.8 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.3 3.5 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.3 2.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.3 1.0 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.3 2.0 GO:0001515 opioid peptide activity(GO:0001515)
0.2 2.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.2 1.6 GO:0030492 hemoglobin binding(GO:0030492)
0.2 0.9 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.2 4.9 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.2 1.4 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2 6.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 0.8 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.2 1.0 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 1.5 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 0.4 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1 1.1 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.4 GO:0043532 angiostatin binding(GO:0043532)
0.1 2.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.8 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.6 GO:0019808 polyamine binding(GO:0019808)
0.1 1.1 GO:0031432 titin binding(GO:0031432)
0.1 1.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 1.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 2.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.2 GO:0070002 glutamic-type peptidase activity(GO:0070002)
0.1 0.3 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 1.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.5 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.5 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.0 0.2 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.0 0.5 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.1 GO:0036478 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478) cupric ion binding(GO:1903135)
0.0 0.2 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 1.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.3 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0071253 connexin binding(GO:0071253)
0.0 1.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.8 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.8 PID RHOA PATHWAY RhoA signaling pathway
0.1 2.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 4.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 3.7 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.1 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.1 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 13.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 2.9 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 3.1 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 15.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 3.5 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 2.1 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.1 3.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 3.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 2.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.0 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 2.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 2.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.8 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.5 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 1.3 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization