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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Nr4a3

Z-value: 0.79

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Transcription factors associated with Nr4a3

Gene Symbol Gene ID Gene Info
Nr4a3
ENSMUSG00000028341.10 Nr4a3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr4a3mm39_v1_chr4_+_48045143_48045160-0.171.4e-01Click!

Activity profile of Nr4a3 motif

Sorted Z-values of Nr4a3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr4a3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr7_+_125202653 4.64 ENSMUST00000206103.2
ENSMUST00000033000.8
Il21r
interleukin 21 receptor
chr7_-_127805518 4.37 ENSMUST00000033049.9
Cox6a2
cytochrome c oxidase subunit 6A2
chr6_+_41523664 4.00 ENSMUST00000103299.3
Trbc2
T cell receptor beta, constant 2
chr3_-_101195213 3.84 ENSMUST00000029456.5
Cd2
CD2 antigen
chr11_+_70548022 3.60 ENSMUST00000157027.8
ENSMUST00000072841.12
ENSMUST00000108548.8
ENSMUST00000126241.8
Eno3
enolase 3, beta muscle
chr15_-_78449172 3.42 ENSMUST00000230952.2
Rac2
Rac family small GTPase 2
chr11_+_70548622 3.29 ENSMUST00000170716.8
Eno3
enolase 3, beta muscle
chr4_+_131600918 3.14 ENSMUST00000053819.6
Srsf4
serine and arginine-rich splicing factor 4
chr14_-_70414236 2.82 ENSMUST00000153735.8
Pdlim2
PDZ and LIM domain 2
chr2_-_13496624 2.68 ENSMUST00000091436.7
Cubn
cubilin (intrinsic factor-cobalamin receptor)
chr8_-_124621483 2.54 ENSMUST00000034453.6
ENSMUST00000212584.2
Acta1
actin, alpha 1, skeletal muscle
chr5_+_34527230 2.44 ENSMUST00000180376.8
Fam193a
family with sequence homology 193, member A
chr15_-_5273659 2.37 ENSMUST00000047379.15
Ptger4
prostaglandin E receptor 4 (subtype EP4)
chr6_+_113508636 2.37 ENSMUST00000036340.12
ENSMUST00000204827.3
Fancd2
Fanconi anemia, complementation group D2
chr15_-_5273645 2.30 ENSMUST00000120563.2
Ptger4
prostaglandin E receptor 4 (subtype EP4)
chr5_+_67125759 2.30 ENSMUST00000238993.2
ENSMUST00000038188.14
Limch1
LIM and calponin homology domains 1
chr15_-_63932288 2.26 ENSMUST00000063838.11
ENSMUST00000228908.2
Cyrib
CYFIP related Rac1 interactor B
chr17_-_74257164 2.20 ENSMUST00000024866.6
Xdh
xanthine dehydrogenase
chr3_-_104725853 2.17 ENSMUST00000106775.8
ENSMUST00000166979.8
Mov10
Mov10 RISC complex RNA helicase
chrX_-_149372840 2.16 ENSMUST00000112725.8
ENSMUST00000112720.8
Apex2
apurinic/apyrimidinic endonuclease 2
chr7_-_79492091 2.09 ENSMUST00000049004.8
Anpep
alanyl (membrane) aminopeptidase
chr19_-_7218363 2.05 ENSMUST00000236769.2
Naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit
chr16_-_4340920 2.04 ENSMUST00000090500.10
ENSMUST00000023161.8
Srl
sarcalumenin
chr3_-_104725581 1.98 ENSMUST00000168015.8
Mov10
Mov10 RISC complex RNA helicase
chr14_-_54655079 1.94 ENSMUST00000226753.2
ENSMUST00000197440.5
Slc7a7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr2_+_69500444 1.88 ENSMUST00000100050.4
Klhl41
kelch-like 41
chr6_-_116693849 1.72 ENSMUST00000056623.13
Tmem72
transmembrane protein 72
chr10_-_23226684 1.71 ENSMUST00000220299.2
Eya4
EYA transcriptional coactivator and phosphatase 4
chr12_-_110945415 1.66 ENSMUST00000135131.2
ENSMUST00000043459.13
ENSMUST00000128353.8
Ankrd9
ankyrin repeat domain 9
chr11_-_61384998 1.63 ENSMUST00000101085.9
ENSMUST00000079080.13
ENSMUST00000108714.2
Mapk7
mitogen-activated protein kinase 7
chr7_+_43910845 1.61 ENSMUST00000124863.4
Gm15517
predicted gene 15517
chr2_+_164647002 1.56 ENSMUST00000052107.5
Zswim3
zinc finger SWIM-type containing 3
chr10_-_80184238 1.56 ENSMUST00000095446.10
ENSMUST00000105352.2
Adamtsl5
ADAMTS-like 5
chr12_-_110945052 1.54 ENSMUST00000140788.8
Ankrd9
ankyrin repeat domain 9
chr15_+_84553801 1.54 ENSMUST00000171460.8
Prr5
proline rich 5 (renal)
chr12_-_110945376 1.50 ENSMUST00000142012.2
Ankrd9
ankyrin repeat domain 9
chr3_-_104725535 1.48 ENSMUST00000002297.12
Mov10
Mov10 RISC complex RNA helicase
chr4_-_126096551 1.47 ENSMUST00000080919.12
Thrap3
thyroid hormone receptor associated protein 3
chr2_+_153850177 1.44 ENSMUST00000048103.9
ENSMUST00000145388.2
Bpifa2
BPI fold containing family A, member 2
chr7_-_79115915 1.43 ENSMUST00000073889.14
Polg
polymerase (DNA directed), gamma
chr3_-_95041246 1.43 ENSMUST00000172572.9
ENSMUST00000173462.3
Scnm1
sodium channel modifier 1
chr6_-_137548004 1.41 ENSMUST00000100841.9
Eps8
epidermal growth factor receptor pathway substrate 8
chr17_+_29579882 1.41 ENSMUST00000024810.8
Fgd2
FYVE, RhoGEF and PH domain containing 2
chr14_-_8798841 1.38 ENSMUST00000061045.3
Sntn
sentan, cilia apical structure protein
chr15_-_76084776 1.33 ENSMUST00000169108.8
ENSMUST00000170728.8
Plec
plectin
chr11_-_100713348 1.33 ENSMUST00000107358.9
Stat5b
signal transducer and activator of transcription 5B
chr17_-_36220518 1.32 ENSMUST00000141132.2
Atat1
alpha tubulin acetyltransferase 1
chr17_-_27842237 1.31 ENSMUST00000062397.13
ENSMUST00000176876.8
ENSMUST00000146321.3
Nudt3
nudix (nucleotide diphosphate linked moiety X)-type motif 3
chr14_-_52252003 1.30 ENSMUST00000226522.2
Zfp219
zinc finger protein 219
chr16_-_50411484 1.30 ENSMUST00000062439.6
Ccdc54
coiled-coil domain containing 54
chr15_+_100659622 1.28 ENSMUST00000023776.13
Slc4a8
solute carrier family 4 (anion exchanger), member 8
chr11_-_105346120 1.27 ENSMUST00000138977.8
Marchf10
membrane associated ring-CH-type finger 10
chr9_-_21913896 1.25 ENSMUST00000044926.6
Odad3
outer dynein arm docking complex subunit 3
chr15_-_63932176 1.24 ENSMUST00000226675.2
ENSMUST00000228226.2
ENSMUST00000227024.2
Cyrib
CYFIP related Rac1 interactor B
chr1_-_160079007 1.23 ENSMUST00000191909.6
Rabgap1l
RAB GTPase activating protein 1-like
chrX_+_55493325 1.17 ENSMUST00000079663.7
Gm2174
predicted gene 2174
chr3_+_101993787 1.16 ENSMUST00000165540.9
ENSMUST00000164123.2
Casq2
calsequestrin 2
chr15_-_102425241 1.14 ENSMUST00000169162.8
ENSMUST00000023812.10
ENSMUST00000165174.8
ENSMUST00000169367.8
ENSMUST00000169377.8
Map3k12
mitogen-activated protein kinase kinase kinase 12
chr11_+_115366470 1.12 ENSMUST00000035240.7
Armc7
armadillo repeat containing 7
chr2_+_79538124 1.12 ENSMUST00000090760.9
ENSMUST00000040863.11
ENSMUST00000111780.3
Ppp1r1c
protein phosphatase 1, regulatory inhibitor subunit 1C
chr4_-_126096376 1.11 ENSMUST00000106142.8
ENSMUST00000169403.8
ENSMUST00000130334.2
Thrap3
thyroid hormone receptor associated protein 3
chr7_-_79115760 1.11 ENSMUST00000125562.2
Polg
polymerase (DNA directed), gamma
chr3_-_137837117 1.10 ENSMUST00000029805.13
Mttp
microsomal triglyceride transfer protein
chr2_-_157121440 1.05 ENSMUST00000143663.2
Mroh8
maestro heat-like repeat family member 8
chr5_+_67125902 1.04 ENSMUST00000127184.8
Limch1
LIM and calponin homology domains 1
chr14_-_52252318 1.03 ENSMUST00000228051.2
Zfp219
zinc finger protein 219
chr9_-_21913833 1.01 ENSMUST00000115336.10
Odad3
outer dynein arm docking complex subunit 3
chr8_+_120588977 0.99 ENSMUST00000034287.10
Klhl36
kelch-like 36
chr17_+_47905553 0.99 ENSMUST00000182846.3
Ccnd3
cyclin D3
chr2_+_158636727 0.99 ENSMUST00000029186.14
ENSMUST00000109478.9
ENSMUST00000156893.2
Dhx35
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr2_-_167334746 0.98 ENSMUST00000109211.9
ENSMUST00000057627.16
Spata2
spermatogenesis associated 2
chr2_-_163259012 0.94 ENSMUST00000127038.2
Oser1
oxidative stress responsive serine rich 1
chr6_-_76474767 0.91 ENSMUST00000097218.7
Gm9008
predicted pseudogene 9008
chr18_-_60757361 0.90 ENSMUST00000097566.10
Synpo
synaptopodin
chr12_-_84240781 0.88 ENSMUST00000110294.2
Mideas
mitotic deacetylase associated SANT domain protein
chr19_+_46140942 0.87 ENSMUST00000026254.14
Gbf1
golgi-specific brefeldin A-resistance factor 1
chr3_-_59038634 0.84 ENSMUST00000200358.2
ENSMUST00000197220.2
P2ry14
purinergic receptor P2Y, G-protein coupled, 14
chr3_-_59038539 0.82 ENSMUST00000198838.2
P2ry14
purinergic receptor P2Y, G-protein coupled, 14
chr7_-_109215754 0.80 ENSMUST00000084738.5
Denn2b
DENN domain containing 2B
chr8_-_121394742 0.80 ENSMUST00000181334.2
ENSMUST00000181950.2
ENSMUST00000181333.2
Emc8
Gm27021
ER membrane protein complex subunit 8
predicted gene, 27021
chr14_+_53007210 0.80 ENSMUST00000178768.4
Trav7d-4
T cell receptor alpha variable 7D-4
chr3_-_89121147 0.79 ENSMUST00000173477.8
ENSMUST00000119222.9
Mtx1
metaxin 1
chr14_-_52252432 0.77 ENSMUST00000226527.2
Zfp219
zinc finger protein 219
chr3_+_5815863 0.75 ENSMUST00000192045.2
Gm8797
predicted pseudogene 8797
chr19_+_37184927 0.73 ENSMUST00000024078.15
ENSMUST00000112391.8
Marchf5
membrane associated ring-CH-type finger 5
chr16_+_84631789 0.72 ENSMUST00000114184.8
Gabpa
GA repeat binding protein, alpha
chr1_-_152262425 0.70 ENSMUST00000015124.15
Tsen15
tRNA splicing endonuclease subunit 15
chr15_+_100659729 0.70 ENSMUST00000161564.2
Slc4a8
solute carrier family 4 (anion exchanger), member 8
chr8_-_105350533 0.68 ENSMUST00000212662.2
Cdh16
cadherin 16
chr2_-_76698725 0.68 ENSMUST00000149616.8
ENSMUST00000152185.8
ENSMUST00000130915.8
ENSMUST00000155365.8
ENSMUST00000128071.8
Ttn
titin
chr17_-_36220924 0.67 ENSMUST00000141662.8
ENSMUST00000056034.13
ENSMUST00000077494.13
ENSMUST00000149277.8
ENSMUST00000061052.12
Atat1
alpha tubulin acetyltransferase 1
chr9_-_18585826 0.66 ENSMUST00000208663.2
Muc16
mucin 16
chr2_-_165125519 0.62 ENSMUST00000155289.8
Slc35c2
solute carrier family 35, member C2
chr11_-_72157450 0.61 ENSMUST00000021161.14
Slc13a5
solute carrier family 13 (sodium-dependent citrate transporter), member 5
chr19_-_37184692 0.61 ENSMUST00000132580.8
ENSMUST00000079754.11
ENSMUST00000136286.8
ENSMUST00000126188.8
ENSMUST00000126781.2
Cpeb3
cytoplasmic polyadenylation element binding protein 3
chr8_-_105350898 0.60 ENSMUST00000212882.2
ENSMUST00000163783.4
Cdh16
cadherin 16
chr5_-_23881353 0.58 ENSMUST00000198661.5
Srpk2
serine/arginine-rich protein specific kinase 2
chr7_-_126074256 0.57 ENSMUST00000205440.2
ENSMUST00000032978.8
ENSMUST00000205340.2
Sh2b1
SH2B adaptor protein 1
chr19_-_40371016 0.56 ENSMUST00000225766.3
Sorbs1
sorbin and SH3 domain containing 1
chr7_+_110368037 0.54 ENSMUST00000213373.2
Ampd3
adenosine monophosphate deaminase 3
chr5_+_16758777 0.54 ENSMUST00000030683.8
Hgf
hepatocyte growth factor
chr13_+_73476629 0.52 ENSMUST00000221730.2
Mrpl36
mitochondrial ribosomal protein L36
chr4_+_150999019 0.51 ENSMUST00000135169.8
Tnfrsf9
tumor necrosis factor receptor superfamily, member 9
chr8_-_105350881 0.50 ENSMUST00000211903.2
Cdh16
cadherin 16
chr6_+_124986627 0.48 ENSMUST00000046064.17
ENSMUST00000152752.8
ENSMUST00000088308.10
ENSMUST00000112425.8
ENSMUST00000084275.12
Zfp384
zinc finger protein 384
chr19_-_45986919 0.47 ENSMUST00000045396.9
Armh3
armadillo-like helical domain containing 3
chr3_+_63883527 0.47 ENSMUST00000029405.8
Gmps
guanine monophosphate synthetase
chr11_-_72157419 0.46 ENSMUST00000208056.2
ENSMUST00000208912.2
ENSMUST00000140167.3
ENSMUST00000137701.3
Slc13a5
solute carrier family 13 (sodium-dependent citrate transporter), member 5
chr3_+_122298308 0.43 ENSMUST00000199358.2
Bcar3
breast cancer anti-estrogen resistance 3
chr8_-_105350816 0.43 ENSMUST00000212447.2
Cdh16
cadherin 16
chr1_+_75412574 0.42 ENSMUST00000037796.14
ENSMUST00000113584.8
ENSMUST00000145166.8
ENSMUST00000143730.8
ENSMUST00000133418.8
ENSMUST00000144874.8
ENSMUST00000140287.8
Gmppa
GDP-mannose pyrophosphorylase A
chr7_-_126074222 0.41 ENSMUST00000205497.2
Sh2b1
SH2B adaptor protein 1
chr4_-_152213315 0.40 ENSMUST00000049305.14
Espn
espin
chr11_+_116547932 0.39 ENSMUST00000116318.3
Prcd
photoreceptor disc component
chrX_+_149372903 0.39 ENSMUST00000080884.11
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr4_+_125952349 0.38 ENSMUST00000035497.5
ENSMUST00000143712.3
Oscp1
organic solute carrier partner 1
chr8_-_105350842 0.37 ENSMUST00000212324.2
Cdh16
cadherin 16
chr16_+_10363222 0.37 ENSMUST00000155633.8
ENSMUST00000066345.15
Clec16a
C-type lectin domain family 16, member A
chr14_+_54453748 0.36 ENSMUST00000103736.2
Traj4
T cell receptor alpha joining 4
chr18_-_60757272 0.34 ENSMUST00000155195.3
Synpo
synaptopodin
chrX_+_74425990 0.34 ENSMUST00000033541.5
Fundc2
FUN14 domain containing 2
chr11_-_4654303 0.33 ENSMUST00000058407.6
Uqcr10
ubiquinol-cytochrome c reductase, complex III subunit X
chr14_+_53073315 0.29 ENSMUST00000197128.2
Trav7d-5
T cell receptor alpha variable 7D-5
chr16_+_4704103 0.29 ENSMUST00000023159.10
ENSMUST00000070658.16
ENSMUST00000229038.2
Mgrn1
mahogunin, ring finger 1
chr4_+_115932466 0.29 ENSMUST00000030471.9
Lrrc41
leucine rich repeat containing 41
chr9_+_21914083 0.29 ENSMUST00000216344.2
Prkcsh
protein kinase C substrate 80K-H
chr5_-_66308666 0.27 ENSMUST00000201561.4
Rbm47
RNA binding motif protein 47
chr8_-_22550035 0.26 ENSMUST00000110738.3
Atp7b
ATPase, Cu++ transporting, beta polypeptide
chr1_-_152262339 0.25 ENSMUST00000162371.2
Tsen15
tRNA splicing endonuclease subunit 15
chr16_+_10363203 0.24 ENSMUST00000115824.10
Clec16a
C-type lectin domain family 16, member A
chr9_+_21914296 0.24 ENSMUST00000003493.9
Prkcsh
protein kinase C substrate 80K-H
chr7_-_109215960 0.23 ENSMUST00000077909.9
Denn2b
DENN domain containing 2B
chr9_+_21914513 0.23 ENSMUST00000215795.2
Prkcsh
protein kinase C substrate 80K-H
chr9_+_21914334 0.22 ENSMUST00000115331.10
Prkcsh
protein kinase C substrate 80K-H
chr13_-_73476561 0.22 ENSMUST00000222930.2
ENSMUST00000223293.2
ENSMUST00000022097.6
Ndufs6
NADH:ubiquinone oxidoreductase core subunit S6
chr5_+_16758897 0.20 ENSMUST00000196645.2
Hgf
hepatocyte growth factor
chr16_+_10363254 0.20 ENSMUST00000115827.8
ENSMUST00000150894.2
ENSMUST00000038145.13
Clec16a
C-type lectin domain family 16, member A
chr4_-_43578823 0.19 ENSMUST00000030189.14
Gba2
glucosidase beta 2
chr8_+_95722289 0.19 ENSMUST00000211984.2
Adgrg1
adhesion G protein-coupled receptor G1
chr15_-_79025387 0.17 ENSMUST00000187550.7
ENSMUST00000188562.7
ENSMUST00000190509.7
ENSMUST00000190730.7
ENSMUST00000190959.7
ENSMUST00000169604.8
ENSMUST00000186053.7
1700088E04Rik
RIKEN cDNA 1700088E04 gene
chr12_-_112640626 0.15 ENSMUST00000001780.10
Akt1
thymoma viral proto-oncogene 1
chr19_-_56996617 0.15 ENSMUST00000118800.8
ENSMUST00000111584.9
ENSMUST00000122359.8
ENSMUST00000148049.8
Afap1l2
actin filament associated protein 1-like 2
chr16_+_4704166 0.06 ENSMUST00000230990.2
Mgrn1
mahogunin, ring finger 1
chr8_+_121394961 0.05 ENSMUST00000034276.13
ENSMUST00000181586.8
Cox4i1
cytochrome c oxidase subunit 4I1
chr7_-_126944754 0.03 ENSMUST00000205266.2
Zfp768
zinc finger protein 768
chr8_-_121394860 0.02 ENSMUST00000034277.14
Emc8
ER membrane protein complex subunit 8
chr14_-_21898992 0.02 ENSMUST00000124549.9
Comtd1
catechol-O-methyltransferase domain containing 1
chr7_+_99659121 0.00 ENSMUST00000107084.8
Chrdl2
chordin-like 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:1904464 negative regulation of integrin activation(GO:0033624) regulation of matrix metallopeptidase secretion(GO:1904464) matrix metallopeptidase secretion(GO:1990773) positive regulation of ovarian follicle development(GO:2000386) regulation of antral ovarian follicle growth(GO:2000387) positive regulation of antral ovarian follicle growth(GO:2000388) negative regulation of eosinophil migration(GO:2000417)
1.4 5.6 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.7 2.0 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.5 1.6 GO:0070376 regulation of ERK5 cascade(GO:0070376)
0.5 2.0 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.4 2.7 GO:0015889 cobalamin transport(GO:0015889)
0.4 2.2 GO:0009115 xanthine catabolic process(GO:0009115)
0.4 1.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.3 3.4 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.3 1.3 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.3 3.2 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.3 0.9 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.3 1.1 GO:0015744 succinate transport(GO:0015744)
0.3 0.8 GO:1904766 negative regulation of macroautophagy by TORC1 signaling(GO:1904766)
0.3 2.4 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.3 3.8 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.2 1.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.2 1.9 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.2 0.6 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.2 1.3 GO:0046544 development of secondary male sexual characteristics(GO:0046544)
0.2 1.7 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.2 1.5 GO:0038203 TORC2 signaling(GO:0038203)
0.2 0.6 GO:0015786 UDP-glucose transport(GO:0015786)
0.1 1.2 GO:0071313 cellular response to caffeine(GO:0071313)
0.1 1.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 2.5 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.1 1.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 1.7 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 1.9 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.1 2.1 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.1 0.6 GO:0035063 nuclear speck organization(GO:0035063)
0.1 1.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.3 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 0.7 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 2.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 2.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 3.1 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 2.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 1.0 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.5 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.7 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.1 0.5 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.1 4.2 GO:0009060 aerobic respiration(GO:0009060)
0.1 0.4 GO:0006000 fructose metabolic process(GO:0006000) fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.5 GO:0032264 IMP salvage(GO:0032264)
0.1 0.7 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 6.9 GO:0006096 glycolytic process(GO:0006096)
0.1 0.4 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 2.2 GO:0006284 base-excision repair(GO:0006284)
0.0 1.0 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.2 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.0 1.0 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.2 GO:0035855 megakaryocyte development(GO:0035855)
0.0 4.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 1.1 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 2.0 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.4 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 1.0 GO:0045840 positive regulation of mitotic nuclear division(GO:0045840)
0.0 1.4 GO:0043507 positive regulation of JUN kinase activity(GO:0043507)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0005760 gamma DNA polymerase complex(GO:0005760)
0.5 2.7 GO:0043202 lysosomal lumen(GO:0043202)
0.5 6.9 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.4 1.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.3 0.8 GO:0036020 endolysosome membrane(GO:0036020)
0.2 1.0 GO:0017177 glucosidase II complex(GO:0017177)
0.2 1.2 GO:0097444 spine apparatus(GO:0097444)
0.2 2.0 GO:0097427 microtubule bundle(GO:0097427)
0.1 2.1 GO:0031983 vesicle lumen(GO:0031983)
0.1 0.4 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 1.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.5 GO:0031932 TORC2 complex(GO:0031932)
0.1 1.9 GO:0031143 pseudopodium(GO:0031143)
0.1 2.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 3.2 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 3.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 1.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 5.6 GO:0016528 sarcoplasm(GO:0016528)
0.0 1.1 GO:0031528 microvillus membrane(GO:0031528)
0.0 2.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 5.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 4.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.4 GO:0032426 stereocilium tip(GO:0032426)
0.0 2.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 2.9 GO:0005884 actin filament(GO:0005884)
0.0 1.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.2 GO:0097451 glial limiting end-foot(GO:0097451)
0.0 4.7 GO:0031965 nuclear membrane(GO:0031965)
0.0 2.8 GO:0001650 fibrillar center(GO:0001650)
0.0 1.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 3.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.7 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.5 2.2 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.5 6.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.4 2.2 GO:0004854 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726) molybdenum ion binding(GO:0030151) molybdopterin cofactor binding(GO:0043546)
0.4 2.7 GO:0030492 hemoglobin binding(GO:0030492)
0.4 1.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.2 3.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 2.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.2 1.3 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.2 2.0 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 1.0 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 1.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 2.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 1.9 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 2.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.7 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 2.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 2.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 2.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 1.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.3 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.1 1.6 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.2 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 0.7 GO:0031433 telethonin binding(GO:0031433)
0.1 2.6 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 1.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 1.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 7.8 GO:0003823 antigen binding(GO:0003823)
0.0 0.5 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 1.3 GO:0030506 ankyrin binding(GO:0030506)
0.0 1.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 2.6 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 3.0 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 4.0 GO:0004386 helicase activity(GO:0004386)
0.0 1.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.7 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 3.4 GO:0019887 protein kinase regulator activity(GO:0019887)
0.0 3.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.1 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 1.1 GO:0005080 protein kinase C binding(GO:0005080)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 PID ATM PATHWAY ATM pathway
0.1 3.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 2.8 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 2.5 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.9 PID ARF 3PATHWAY Arf1 pathway
0.0 1.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.7 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.8 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.5 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.7 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.2 2.4 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.2 5.6 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 7.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.6 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 2.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 3.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 2.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.9 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 2.7 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 1.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 3.1 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 1.0 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.0 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 3.8 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME PURINE METABOLISM Genes involved in Purine metabolism
0.0 1.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 2.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import