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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Nr6a1

Z-value: 1.35

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Transcription factors associated with Nr6a1

Gene Symbol Gene ID Gene Info
Nr6a1
ENSMUSG00000063972.14 Nr6a1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr6a1mm39_v1_chr2_-_38816229_38816366-0.352.9e-03Click!

Activity profile of Nr6a1 motif

Sorted Z-values of Nr6a1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr6a1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr12_+_31440842 14.23 ENSMUST00000167432.8
Slc26a3
solute carrier family 26, member 3
chrX_-_7884688 13.37 ENSMUST00000033503.3
Glod5
glyoxalase domain containing 5
chr12_-_114878652 12.79 ENSMUST00000103515.2
Ighv1-39
immunoglobulin heavy variable 1-39
chr12_-_115884332 12.79 ENSMUST00000103548.3
Ighv1-81
immunoglobulin heavy variable 1-81
chr12_-_114672701 11.93 ENSMUST00000103505.3
ENSMUST00000193855.2
Ighv1-19
immunoglobulin heavy variable V1-19
chr12_-_115299134 11.45 ENSMUST00000195359.6
ENSMUST00000103530.3
Ighv1-59
immunoglobulin heavy variable V1-59
chr12_-_114752425 10.60 ENSMUST00000103510.2
Ighv1-26
immunoglobulin heavy variable 1-26
chr12_-_115916604 10.07 ENSMUST00000196991.2
Ighv1-82
immunoglobulin heavy variable 1-82
chr12_-_114579938 10.03 ENSMUST00000195469.6
ENSMUST00000109711.4
Ighv1-12
immunoglobulin heavy variable V1-12
chr12_-_114621406 9.96 ENSMUST00000192077.2
Ighv1-15
immunoglobulin heavy variable 1-15
chr12_-_114901026 9.75 ENSMUST00000103516.2
ENSMUST00000191868.2
Ighv1-42
immunoglobulin heavy variable V1-42
chr12_-_114579763 9.21 ENSMUST00000103500.2
Ighv1-12
immunoglobulin heavy variable V1-12
chr12_-_114547622 9.15 ENSMUST00000193893.6
ENSMUST00000103498.3
Ighv1-9
immunoglobulin heavy variable V1-9
chr12_-_115832846 9.09 ENSMUST00000199373.2
Ighv1-78
immunoglobulin heavy variable 1-78
chr4_-_138484889 8.99 ENSMUST00000030526.7
Pla2g2f
phospholipase A2, group IIF
chr12_-_115083839 8.89 ENSMUST00000103521.3
Ighv1-50
immunoglobulin heavy variable 1-50
chr12_-_114815280 8.10 ENSMUST00000103512.3
Ighv1-34
immunoglobulin heavy variable 1-34
chr12_-_114646685 7.70 ENSMUST00000194350.6
ENSMUST00000103504.3
Ighv1-18
immunoglobulin heavy variable V1-18
chr12_-_113896002 7.48 ENSMUST00000103463.3
Ighv14-1
immunoglobulin heavy variable 14-1
chr14_-_121742659 7.35 ENSMUST00000088386.8
Slc15a1
solute carrier family 15 (oligopeptide transporter), member 1
chr5_-_137609634 7.03 ENSMUST00000054564.13
Pcolce
procollagen C-endopeptidase enhancer protein
chr5_-_137609691 6.97 ENSMUST00000031731.14
Pcolce
procollagen C-endopeptidase enhancer protein
chr17_-_57535003 6.71 ENSMUST00000177046.2
ENSMUST00000024988.15
C3
complement component 3
chr5_+_114141739 6.35 ENSMUST00000112292.9
Dao
D-amino acid oxidase
chr17_-_35023521 5.78 ENSMUST00000025223.9
Cyp21a1
cytochrome P450, family 21, subfamily a, polypeptide 1
chr17_-_27247581 5.77 ENSMUST00000143158.3
Bak1
BCL2-antagonist/killer 1
chr12_-_115587215 5.41 ENSMUST00000199933.5
ENSMUST00000103539.3
Ighv1-69
immunoglobulin heavy variable 1-69
chr15_+_31572251 5.34 ENSMUST00000161088.3
Cmbl
carboxymethylenebutenolidase-like (Pseudomonas)
chr5_-_137608886 5.20 ENSMUST00000142675.8
Pcolce
procollagen C-endopeptidase enhancer protein
chr4_-_45530330 5.15 ENSMUST00000061986.12
Shb
src homology 2 domain-containing transforming protein B
chr19_+_46695889 4.96 ENSMUST00000003655.9
As3mt
arsenite methyltransferase
chr19_+_47843461 4.76 ENSMUST00000237121.2
Gsto1
glutathione S-transferase omega 1
chr11_-_60702081 4.68 ENSMUST00000018744.15
Shmt1
serine hydroxymethyltransferase 1 (soluble)
chr5_+_114141894 4.66 ENSMUST00000086599.11
Dao
D-amino acid oxidase
chr12_-_114955196 4.57 ENSMUST00000194865.2
Ighv1-47
immunoglobulin heavy variable 1-47
chr14_+_79086665 4.37 ENSMUST00000227255.2
Vwa8
von Willebrand factor A domain containing 8
chr9_-_50515089 4.34 ENSMUST00000000175.6
Sdhd
succinate dehydrogenase complex, subunit D, integral membrane protein
chr6_+_42222841 4.32 ENSMUST00000031897.8
Gstk1
glutathione S-transferase kappa 1
chr6_+_21985902 4.05 ENSMUST00000115383.9
Cped1
cadherin-like and PC-esterase domain containing 1
chr5_+_64969679 4.04 ENSMUST00000166409.6
ENSMUST00000197879.2
Klf3
Kruppel-like factor 3 (basic)
chr12_-_114843941 4.03 ENSMUST00000191862.6
ENSMUST00000103513.3
Ighv1-36
immunoglobulin heavy variable 1-36
chr6_-_124613044 3.78 ENSMUST00000068797.3
ENSMUST00000218020.2
C1s2
complement component 1, s subcomponent 2
chr10_+_21854540 3.66 ENSMUST00000142174.8
ENSMUST00000164659.8
Sgk1
serum/glucocorticoid regulated kinase 1
chr12_-_115459678 3.63 ENSMUST00000103534.2
Ighv1-63
immunoglobulin heavy variable V1-63
chr1_+_131898325 3.61 ENSMUST00000027695.8
Slc45a3
solute carrier family 45, member 3
chr4_-_82423511 3.53 ENSMUST00000050872.15
ENSMUST00000064770.9
Nfib
nuclear factor I/B
chrX_+_156485570 3.49 ENSMUST00000112520.2
Smpx
small muscle protein, X-linked
chr7_-_132178101 3.43 ENSMUST00000084500.8
Oat
ornithine aminotransferase
chr6_-_113411489 3.38 ENSMUST00000133348.2
Cidec
cell death-inducing DFFA-like effector c
chr12_-_115206715 3.38 ENSMUST00000103527.2
ENSMUST00000194071.2
Ighv1-56
immunoglobulin heavy variable 1-56
chr14_+_79086492 3.37 ENSMUST00000040990.7
Vwa8
von Willebrand factor A domain containing 8
chr9_+_98178646 3.35 ENSMUST00000112938.8
ENSMUST00000112937.3
Nmnat3
nicotinamide nucleotide adenylyltransferase 3
chr11_+_83742961 3.24 ENSMUST00000146786.8
Hnf1b
HNF1 homeobox B
chr9_+_98178608 3.21 ENSMUST00000112935.8
Nmnat3
nicotinamide nucleotide adenylyltransferase 3
chr12_-_114687825 3.06 ENSMUST00000194968.6
ENSMUST00000103506.3
Ighv1-20
immunoglobulin heavy variable V1-20
chr15_-_77653979 3.03 ENSMUST00000229259.2
Myh9
myosin, heavy polypeptide 9, non-muscle
chr17_+_73225292 2.86 ENSMUST00000024857.14
Lbh
limb-bud and heart
chr17_-_46956054 2.73 ENSMUST00000003642.7
Klc4
kinesin light chain 4
chrX_+_156482116 2.73 ENSMUST00000112521.8
Smpx
small muscle protein, X-linked
chr5_-_5744326 2.72 ENSMUST00000148333.8
Steap2
six transmembrane epithelial antigen of prostate 2
chr7_+_110368037 2.71 ENSMUST00000213373.2
Ampd3
adenosine monophosphate deaminase 3
chr4_+_123798625 2.61 ENSMUST00000030400.14
Mycbp
MYC binding protein
chr16_+_10297923 2.57 ENSMUST00000230395.2
Ciita
class II transactivator
chr10_+_127919142 2.51 ENSMUST00000026459.6
Atp5b
ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
chr16_+_22769822 2.43 ENSMUST00000023590.9
Hrg
histidine-rich glycoprotein
chr9_-_118986123 2.43 ENSMUST00000010795.5
Acaa1b
acetyl-Coenzyme A acyltransferase 1B
chr12_-_115964081 2.28 ENSMUST00000103552.2
Ighv1-85
immunoglobulin heavy variable 1-85
chr14_+_58310143 2.25 ENSMUST00000022545.14
Fgf9
fibroblast growth factor 9
chr15_+_84553801 2.22 ENSMUST00000171460.8
Prr5
proline rich 5 (renal)
chr6_+_21986445 2.16 ENSMUST00000115382.8
Cped1
cadherin-like and PC-esterase domain containing 1
chr5_+_137015873 2.09 ENSMUST00000004968.11
Plod3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr5_-_108822619 2.03 ENSMUST00000119270.2
ENSMUST00000163328.8
ENSMUST00000136227.2
Slc26a1
solute carrier family 26 (sulfate transporter), member 1
chr18_-_6135888 2.03 ENSMUST00000182383.8
ENSMUST00000062584.14
ENSMUST00000077128.13
ENSMUST00000182038.2
ENSMUST00000182213.8
ENSMUST00000182559.8
Arhgap12
Rho GTPase activating protein 12
chr4_+_138161958 2.02 ENSMUST00000044058.11
ENSMUST00000105813.8
ENSMUST00000105815.2
Mul1
mitochondrial ubiquitin ligase activator of NFKB 1
chr7_+_127864847 1.98 ENSMUST00000118169.8
ENSMUST00000206909.2
ENSMUST00000142841.8
Slc5a2
solute carrier family 5 (sodium/glucose cotransporter), member 2
chr11_-_100661762 1.97 ENSMUST00000139341.2
ENSMUST00000017891.14
Ghdc
GH3 domain containing
chr1_+_160806241 1.92 ENSMUST00000195760.2
Serpinc1
serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
chr12_-_115825934 1.83 ENSMUST00000198777.2
Ighv1-77
immunoglobulin heavy variable 1-77
chr16_-_3535940 1.83 ENSMUST00000229725.2
ENSMUST00000100222.4
Mefv
Mediterranean fever
chr1_-_151304191 1.81 ENSMUST00000064771.12
Swt1
SWT1 RNA endoribonuclease homolog (S. cerevisiae)
chr5_-_30278552 1.59 ENSMUST00000198095.2
ENSMUST00000196872.2
ENSMUST00000026846.11
Tyms
thymidylate synthase
chr16_+_22769844 1.56 ENSMUST00000232422.2
Hrg
histidine-rich glycoprotein
chr2_+_32477069 1.54 ENSMUST00000102818.11
St6galnac4
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr4_-_82423985 1.48 ENSMUST00000107245.9
ENSMUST00000107246.2
Nfib
nuclear factor I/B
chr6_+_90310252 1.47 ENSMUST00000046128.12
ENSMUST00000164761.6
Uroc1
urocanase domain containing 1
chr5_-_5744024 1.43 ENSMUST00000115425.9
ENSMUST00000115427.8
ENSMUST00000115424.9
ENSMUST00000015797.11
Steap2
six transmembrane epithelial antigen of prostate 2
chr5_-_5744559 1.43 ENSMUST00000115426.9
Steap2
six transmembrane epithelial antigen of prostate 2
chr5_-_36641456 1.23 ENSMUST00000119916.2
ENSMUST00000031097.8
Tada2b
transcriptional adaptor 2B
chr5_+_114313940 1.20 ENSMUST00000146841.2
Acacb
acetyl-Coenzyme A carboxylase beta
chr12_-_71183371 1.17 ENSMUST00000221367.2
ENSMUST00000220482.2
ENSMUST00000221892.2
ENSMUST00000221178.2
ENSMUST00000221559.2
ENSMUST00000166120.9
ENSMUST00000021486.10
ENSMUST00000221797.2
ENSMUST00000221815.2
Timm9
translocase of inner mitochondrial membrane 9
chr16_-_3535958 1.16 ENSMUST00000023180.15
Mefv
Mediterranean fever
chr2_+_32496957 1.07 ENSMUST00000113290.8
St6galnac6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr5_+_129802127 0.97 ENSMUST00000086046.10
ENSMUST00000186265.6
Nipsnap2
nipsnap homolog 2
chr11_-_76654375 0.91 ENSMUST00000010536.9
Gosr1
golgi SNAP receptor complex member 1
chr18_-_65527078 0.90 ENSMUST00000035548.16
Alpk2
alpha-kinase 2
chr7_+_30014235 0.84 ENSMUST00000054594.15
ENSMUST00000177078.8
ENSMUST00000176504.8
ENSMUST00000176304.8
Syne4
spectrin repeat containing, nuclear envelope family member 4
chr1_+_160806194 0.83 ENSMUST00000064725.11
ENSMUST00000191936.2
Serpinc1
serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
chr11_-_99932373 0.82 ENSMUST00000056362.3
Krt34
keratin 34
chr1_+_151304293 0.81 ENSMUST00000065625.12
Trmt1l
tRNA methyltransferase 1 like
chr2_+_157266175 0.79 ENSMUST00000029175.14
ENSMUST00000092576.11
Src
Rous sarcoma oncogene
chr4_-_82423944 0.76 ENSMUST00000107248.8
ENSMUST00000107247.8
Nfib
nuclear factor I/B
chr5_-_137015683 0.74 ENSMUST00000034953.14
ENSMUST00000085941.12
Znhit1
zinc finger, HIT domain containing 1
chr8_+_75836187 0.74 ENSMUST00000164309.3
ENSMUST00000212426.2
ENSMUST00000212811.2
Mcm5
minichromosome maintenance complex component 5
chr15_-_50753061 0.73 ENSMUST00000165201.9
ENSMUST00000184458.8
Trps1
transcriptional repressor GATA binding 1
chr6_-_129599645 0.73 ENSMUST00000032252.8
Klrk1
killer cell lectin-like receptor subfamily K, member 1
chr6_-_67468831 0.72 ENSMUST00000118364.2
Il23r
interleukin 23 receptor
chr9_+_45311000 0.65 ENSMUST00000216289.2
Fxyd2
FXYD domain-containing ion transport regulator 2
chr12_-_11200306 0.64 ENSMUST00000055673.2
Kcns3
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
chr9_-_35559489 0.62 ENSMUST00000178236.3
Pate3
prostate and testis expressed 3
chr4_+_123095297 0.62 ENSMUST00000068262.6
Nt5c1a
5'-nucleotidase, cytosolic IA
chr2_+_32496990 0.56 ENSMUST00000095045.9
ENSMUST00000095044.10
ENSMUST00000126636.8
St6galnac6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr13_-_24945423 0.54 ENSMUST00000176890.8
ENSMUST00000175689.8
Gmnn
geminin
chr4_-_134279433 0.46 ENSMUST00000060435.8
Selenon
selenoprotein N
chr18_+_65020885 0.43 ENSMUST00000236209.2
Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr9_+_78234871 0.37 ENSMUST00000187667.7
Omt2b
oocyte maturation, beta
chr16_+_11140740 0.37 ENSMUST00000180792.8
Snx29
sorting nexin 29
chr9_-_38899578 0.32 ENSMUST00000216823.2
ENSMUST00000214324.3
Olfr934
olfactory receptor 934
chr18_+_65020760 0.29 ENSMUST00000235343.2
Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr9_-_78221298 0.22 ENSMUST00000166056.9
Omt2a
oocyte maturation, alpha
chr12_+_114594300 0.22 ENSMUST00000095364.3
ENSMUSG00000090765.2

chr9_+_38382403 0.21 ENSMUST00000214377.2
Olfr905
olfactory receptor 905
chr10_+_23846604 0.19 ENSMUST00000092659.4
Taar5
trace amine-associated receptor 5
chr5_-_108120730 0.15 ENSMUST00000153172.2
Dipk1a
divergent protein kinase domain 1A
chr5_+_8943943 0.14 ENSMUST00000196067.2
Abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr4_+_123798690 0.11 ENSMUST00000106202.4
Mycbp
MYC binding protein
chr12_-_28673259 0.10 ENSMUST00000220836.2
Colec11
collectin sub-family member 11
chr12_-_28673311 0.09 ENSMUST00000036136.9
Colec11
collectin sub-family member 11
chr9_+_122634589 0.08 ENSMUST00000052740.14
Tcaim
T cell activation inhibitor, mitochondrial
chr4_-_138858340 0.02 ENSMUST00000143971.2
Micos10
mitochondrial contact site and cristae organizing system subunit 10

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 11.0 GO:0036088 D-serine catabolic process(GO:0036088) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
1.7 6.7 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
1.6 4.7 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
1.4 5.8 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
1.4 5.8 GO:0010046 response to mycotoxin(GO:0010046)
1.3 4.0 GO:0097037 heme export(GO:0097037)
1.2 186.9 GO:0006910 phagocytosis, recognition(GO:0006910)
1.1 14.2 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
1.1 6.6 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
1.0 7.3 GO:0042938 dipeptide transport(GO:0042938)
1.0 3.0 GO:0071640 regulation of macrophage inflammatory protein 1 alpha production(GO:0071640)
1.0 4.8 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.9 3.6 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.9 4.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.8 3.2 GO:0061215 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.8 3.0 GO:1903921 protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.6 5.6 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.5 5.2 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.4 2.1 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.4 2.0 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
0.4 1.2 GO:2001293 fatty-acyl-CoA biosynthetic process(GO:0046949) malonyl-CoA metabolic process(GO:2001293)
0.4 1.6 GO:0046073 dTMP biosynthetic process(GO:0006231) dTMP metabolic process(GO:0046073)
0.4 3.4 GO:0034214 protein hexamerization(GO:0034214)
0.4 2.5 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.4 2.9 GO:1904672 regulation of somatic stem cell population maintenance(GO:1904672)
0.3 2.8 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.3 5.8 GO:0006705 mineralocorticoid biosynthetic process(GO:0006705)
0.3 3.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.3 1.5 GO:0006548 histidine catabolic process(GO:0006548)
0.3 2.0 GO:0019532 oxalate transport(GO:0019532)
0.3 2.7 GO:0032264 IMP salvage(GO:0032264)
0.3 0.8 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.2 2.2 GO:0038203 TORC2 signaling(GO:0038203)
0.2 0.7 GO:0030887 positive regulation of myeloid dendritic cell activation(GO:0030887)
0.2 1.0 GO:2000983 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
0.2 1.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.2 3.7 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.2 2.6 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.2 5.0 GO:0009404 toxin metabolic process(GO:0009404)
0.2 6.8 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 2.0 GO:1904659 glucose transmembrane transport(GO:1904659)
0.1 3.4 GO:0034389 lipid particle organization(GO:0034389)
0.1 2.2 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.1 1.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.5 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.1 0.7 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.8 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 15.5 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.1 4.3 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 0.9 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.0 0.1 GO:1903412 response to bile acid(GO:1903412) cellular response to bile acid(GO:1903413)
0.0 0.6 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128)
0.0 0.7 GO:0002827 positive regulation of T-helper 1 type immune response(GO:0002827)
0.0 1.5 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 1.2 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.0 0.7 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 2.0 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)
0.0 0.7 GO:0006270 DNA replication initiation(GO:0006270)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 186.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
1.3 4.0 GO:0061474 phagolysosome membrane(GO:0061474)
1.1 4.3 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.8 6.2 GO:0005927 muscle tendon junction(GO:0005927)
0.4 5.8 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.4 3.0 GO:0097513 myosin II filament(GO:0097513)
0.4 14.2 GO:0097225 sperm midpiece(GO:0097225)
0.4 1.2 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.3 2.5 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.3 5.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 5.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 2.2 GO:0031932 TORC2 complex(GO:0031932)
0.1 8.8 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 12.8 GO:0072562 blood microparticle(GO:0072562)
0.1 2.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.2 GO:0030914 STAGA complex(GO:0030914)
0.1 0.7 GO:0000812 Swr1 complex(GO:0000812)
0.0 7.0 GO:0005604 basement membrane(GO:0005604)
0.0 0.7 GO:0042555 MCM complex(GO:0042555)
0.0 9.3 GO:0005903 brush border(GO:0005903)
0.0 0.8 GO:0005640 nuclear outer membrane(GO:0005640) nuclear membrane part(GO:0044453)
0.0 0.9 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 3.4 GO:0005811 lipid particle(GO:0005811)
0.0 2.7 GO:0005871 kinesin complex(GO:0005871)
0.0 13.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 5.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 2.6 GO:0016605 PML body(GO:0016605)
0.0 0.8 GO:0002102 podosome(GO:0002102)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 11.0 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
2.4 7.3 GO:0042936 dipeptide transporter activity(GO:0042936)
1.6 4.7 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372)
1.4 4.3 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
1.4 186.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
1.1 6.6 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.9 16.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.9 3.6 GO:0015154 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.7 5.6 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.7 4.8 GO:0030613 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.6 2.5 GO:0043532 angiostatin binding(GO:0043532)
0.5 3.7 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.4 2.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.3 19.2 GO:0016504 peptidase activator activity(GO:0016504)
0.3 3.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.3 2.7 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 0.7 GO:0032394 MHC class Ib receptor activity(GO:0032394)
0.2 1.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.2 5.8 GO:0051400 BH domain binding(GO:0051400)
0.2 4.3 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.2 6.8 GO:0004623 phospholipase A2 activity(GO:0004623)
0.2 3.0 GO:0043495 protein anchor(GO:0043495)
0.2 2.0 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.2 2.4 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.2 0.8 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.7 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 1.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 5.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 3.4 GO:0008483 transaminase activity(GO:0008483)
0.1 5.8 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 5.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 2.0 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.8 GO:0071253 connexin binding(GO:0071253)
0.1 2.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 4.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 5.0 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.0 2.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 3.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.5 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 2.6 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 6.7 GO:0048037 cofactor binding(GO:0048037)
0.0 0.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.2 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 3.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.8 GO:0002020 protease binding(GO:0002020)
0.0 7.7 GO:0016887 ATPase activity(GO:0016887)
0.0 1.2 GO:0051087 chaperone binding(GO:0051087)
0.0 0.7 GO:0031491 nucleosome binding(GO:0031491)
0.0 2.7 GO:0003713 transcription coactivator activity(GO:0003713)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.3 5.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 5.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 5.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 19.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 3.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 3.7 PID INSULIN PATHWAY Insulin Pathway
0.0 3.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.2 PID FGF PATHWAY FGF signaling pathway
0.0 2.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 2.7 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.6 PID E2F PATHWAY E2F transcription factor network
0.0 0.7 PID IL23 PATHWAY IL23-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 9.0 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.5 6.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.3 21.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 5.8 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.2 16.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.2 3.0 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 4.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 2.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 23.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 2.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 3.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 2.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 2.2 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 5.8 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 3.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 2.7 REACTOME KINESINS Genes involved in Kinesins
0.1 3.2 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 1.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 12.5 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 0.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.5 REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.0 0.8 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 1.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.6 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 2.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 4.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 2.0 REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.0 2.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases