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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Obox1

Z-value: 0.95

Motif logo

Transcription factors associated with Obox1

Gene Symbol Gene ID Gene Info
ENSMUSG00000054310.17 Obox1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Obox1mm39_v1_chr7_+_15122873_151229180.085.1e-01Click!

Activity profile of Obox1 motif

Sorted Z-values of Obox1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Obox1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_-_73615732 9.32 ENSMUST00000029367.6
butyrylcholinesterase
chr4_-_116024788 8.46 ENSMUST00000030465.10
ENSMUST00000143426.2
tetraspanin 1
chr3_+_92123106 7.50 ENSMUST00000074449.7
ENSMUST00000090871.3
small proline-rich protein 2A1
small proline-rich protein 2A2
chr3_-_73615535 7.13 ENSMUST00000138216.8
butyrylcholinesterase
chr11_+_3981769 6.85 ENSMUST00000019512.8
SEC14-like lipid binding 4
chr15_-_76501041 5.54 ENSMUST00000073428.7
solute carrier family 39 (zinc transporter), member 4
chr7_+_88079534 5.04 ENSMUST00000208478.2
RAB38, member RAS oncogene family
chr14_+_14090981 4.87 ENSMUST00000022269.7
oncoprotein induced transcript 1
chr12_-_114621406 4.57 ENSMUST00000192077.2
immunoglobulin heavy variable 1-15
chr15_-_76501525 4.39 ENSMUST00000230977.2
solute carrier family 39 (zinc transporter), member 4
chr9_-_21223551 3.98 ENSMUST00000003397.9
ENSMUST00000213250.2
adaptor protein complex AP-1, mu 2 subunit
chr8_+_110717062 3.96 ENSMUST00000001720.14
ENSMUST00000143741.2
tyrosine aminotransferase
chr3_+_92192724 3.78 ENSMUST00000193337.2
small proline-rich protein 2A3
chr7_+_88079465 3.62 ENSMUST00000107256.4
RAB38, member RAS oncogene family
chr12_-_114672701 3.60 ENSMUST00000103505.3
ENSMUST00000193855.2
immunoglobulin heavy variable V1-19
chr6_-_41012435 3.59 ENSMUST00000031931.6
RIKEN cDNA 2210010C04 gene
chr9_-_35111172 3.59 ENSMUST00000176021.8
ENSMUST00000176531.8
ENSMUST00000176685.8
ENSMUST00000177129.8
toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
chr3_-_92758591 3.34 ENSMUST00000054426.5
late cornified envelope 1L
chr15_-_78739717 3.30 ENSMUST00000044584.6
lectin, galactose-binding, soluble 2
chr6_-_5193816 3.18 ENSMUST00000002663.12
paraoxonase 1
chr6_-_5193757 3.18 ENSMUST00000177159.9
ENSMUST00000176945.2
paraoxonase 1
chr15_+_76579885 3.15 ENSMUST00000231028.2
glutamic pyruvic transaminase, soluble
chr9_-_21223631 3.15 ENSMUST00000115433.11
adaptor protein complex AP-1, mu 2 subunit
chr15_+_76579960 3.01 ENSMUST00000229679.2
glutamic pyruvic transaminase, soluble
chr13_-_58758691 2.94 ENSMUST00000022036.14
solute carrier family 28 (sodium-coupled nucleoside transporter), member 3
chr17_+_87943401 2.93 ENSMUST00000235125.2
ENSMUST00000053577.9
ENSMUST00000234009.2
epithelial cell adhesion molecule
chr12_-_114901026 2.88 ENSMUST00000103516.2
ENSMUST00000191868.2
immunoglobulin heavy variable V1-42
chr7_-_110581652 2.86 ENSMUST00000005751.13
inositol 1,4,5-triphosphate receptor associated 1
chr6_+_70675416 2.84 ENSMUST00000103403.3
immunoglobulin kappa variable 3-2
chr4_-_137157824 2.80 ENSMUST00000102522.5
chymotrypsin-like elastase family, member 3B
chr7_-_110581376 2.79 ENSMUST00000154466.2
inositol 1,4,5-triphosphate receptor associated 1
chr6_-_69282389 2.76 ENSMUST00000103350.3
immunoglobulin kappa variable 4-68
chr1_-_139708906 2.71 ENSMUST00000111986.8
ENSMUST00000027612.11
ENSMUST00000111989.9
complement factor H-related 4
chr16_+_33614378 2.69 ENSMUST00000115044.8
mucin 13, epithelial transmembrane
chr6_+_41155309 2.68 ENSMUST00000103276.3
T cell receptor beta, variable 19
chr14_+_14091030 2.67 ENSMUST00000224529.2
oncoprotein induced transcript 1
chr8_+_114860375 2.56 ENSMUST00000147605.8
ENSMUST00000134593.2
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr5_+_91287448 2.48 ENSMUST00000031325.6
amphiregulin
chr6_+_70348416 2.47 ENSMUST00000103391.4
immunoglobulin kappa variable 6-17
chr14_-_30665232 2.46 ENSMUST00000006704.17
ENSMUST00000163118.2
inter-alpha trypsin inhibitor, heavy chain 1
chr2_-_34803988 2.38 ENSMUST00000028232.7
ENSMUST00000202907.2
PHD finger protein 19
chr6_-_59403264 2.38 ENSMUST00000051065.6
GPRIN family member 3
chr3_+_106389732 2.36 ENSMUST00000029508.11
DENN/MADD domain containing 2D
chr6_-_69204417 2.34 ENSMUST00000103346.3
immunoglobulin kappa chain variable 4-72
chr8_+_114860342 2.34 ENSMUST00000109109.8
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr12_-_114646685 2.33 ENSMUST00000194350.6
ENSMUST00000103504.3
immunoglobulin heavy variable V1-18
chr5_-_105491795 2.32 ENSMUST00000171587.2
guanylate binding protein 11
chr1_-_106980033 2.30 ENSMUST00000112717.3
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A
chr5_-_105198913 2.25 ENSMUST00000112718.5
guanylate-binding protein 8
chr6_+_129385816 2.22 ENSMUST00000058352.15
ENSMUST00000088075.8
C-type lectin domain family 9, member a
chr10_+_127478844 2.19 ENSMUST00000092074.12
ENSMUST00000120279.2
signal transducer and activator of transcription 6
chrX_+_55825033 2.15 ENSMUST00000114772.9
ENSMUST00000114768.10
ENSMUST00000155882.8
four and a half LIM domains 1
chr19_-_40062174 2.15 ENSMUST00000048959.5
cytochrome P450, family 2, subfamily c, polypeptide 54
chr16_+_23109213 2.12 ENSMUST00000115335.2
beta galactoside alpha 2,6 sialyltransferase 1
chr1_+_163889713 2.10 ENSMUST00000097491.10
selectin, lymphocyte
chr19_-_10859087 2.09 ENSMUST00000144681.2
transmembrane protein 109
chr3_+_93227047 2.07 ENSMUST00000090856.10
ENSMUST00000093774.4
hornerin
chr15_+_54975713 2.05 ENSMUST00000096433.10
DEP domain containing MTOR-interacting protein
chr19_+_33985684 2.05 ENSMUST00000225505.2
lipase, family member K
chr16_+_31241085 2.00 ENSMUST00000089759.9
3-hydroxybutyrate dehydrogenase, type 1
chr2_-_62313981 1.97 ENSMUST00000136686.2
ENSMUST00000102733.10
glucagon
chr14_+_14210932 1.97 ENSMUST00000022271.14
acyl-Coenzyme A oxidase 2, branched chain
chr6_-_69553484 1.97 ENSMUST00000103357.4
immunoglobulin kappa variable 4-57
chr6_-_69245427 1.96 ENSMUST00000103348.3
immunoglobulin kappa chain variable 4-70
chr7_+_140547941 1.95 ENSMUST00000106040.8
ENSMUST00000026564.9
interferon induced transmembrane protein 1
chr10_-_86843878 1.94 ENSMUST00000035288.17
stabilin 2
chr7_+_46496929 1.93 ENSMUST00000132157.2
ENSMUST00000210631.2
lactate dehydrogenase A
chr13_-_74918745 1.91 ENSMUST00000223033.2
ENSMUST00000222588.2
calpastatin
chr1_+_178014983 1.91 ENSMUST00000161075.8
ENSMUST00000027783.14
desumoylating isopeptidase 2
chr10_+_97400990 1.90 ENSMUST00000038160.6
lumican
chr19_+_33985701 1.90 ENSMUST00000054260.8
lipase, family member K
chr6_+_41928559 1.87 ENSMUST00000031898.5
seminal vesicle antigen-like 1
chr6_+_129385893 1.87 ENSMUST00000204860.3
ENSMUST00000164513.8
C-type lectin domain family 9, member a
chr3_+_92223927 1.87 ENSMUST00000061038.4
small proline-rich protein 2B
chr13_-_64514830 1.84 ENSMUST00000222971.2
cathepsin L
chr1_-_139487951 1.84 ENSMUST00000023965.8
complement factor H-related 1
chr9_-_14815228 1.82 ENSMUST00000034409.14
ENSMUST00000117620.8
IZUMO1 receptor, JUNO
chr7_-_12732067 1.82 ENSMUST00000032539.14
ENSMUST00000120903.8
solute carrier family 27 (fatty acid transporter), member 5
chr10_+_76284907 1.80 ENSMUST00000092406.12
RIKEN cDNA 2610028H24 gene
chr10_-_76949762 1.78 ENSMUST00000072755.12
collagen, type XVIII, alpha 1
chr10_-_12744025 1.78 ENSMUST00000219660.2
utrophin
chr11_-_101998648 1.76 ENSMUST00000177304.8
ENSMUST00000017455.15
peptide YY
chr11_-_32150222 1.76 ENSMUST00000145401.8
ENSMUST00000142396.2
ENSMUST00000128311.8
interleukin 9 receptor
chr13_-_74918701 1.73 ENSMUST00000223126.2
calpastatin
chr2_-_34990689 1.73 ENSMUST00000226631.2
ENSMUST00000045776.5
ENSMUST00000226972.2
expressed sequence AI182371
chr14_+_40826970 1.73 ENSMUST00000225720.2
methionine adenosyltransferase I, alpha
chr14_-_40907106 1.71 ENSMUST00000077136.5
surfactant associated protein D
chr1_+_107456731 1.71 ENSMUST00000182198.8
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10
chr14_-_25902898 1.69 ENSMUST00000183431.8
ENSMUST00000183725.2
placenta specific 9a
chr6_-_129599645 1.67 ENSMUST00000032252.8
killer cell lectin-like receptor subfamily K, member 1
chr6_+_41139948 1.67 ENSMUST00000103275.4
T cell receptor beta, variable 17
chr19_-_10859046 1.66 ENSMUST00000128835.8
transmembrane protein 109
chr1_-_136888118 1.64 ENSMUST00000192357.6
ENSMUST00000027649.14
nuclear receptor subfamily 5, group A, member 2
chr7_+_101871623 1.63 ENSMUST00000143541.8
post-GPI attachment to proteins 2
chr9_-_50528530 1.63 ENSMUST00000147671.2
ENSMUST00000145139.8
ENSMUST00000155435.8
NKAP domain containing 1
chr11_-_59937302 1.63 ENSMUST00000000310.14
ENSMUST00000102693.9
ENSMUST00000148512.2
phosphatidylethanolamine N-methyltransferase
chr1_+_163889551 1.62 ENSMUST00000192047.6
ENSMUST00000027871.13
selectin, lymphocyte
chr12_-_113552322 1.60 ENSMUST00000103443.3
immunoglobulin heavy variable 2-2
chrX_-_101232978 1.59 ENSMUST00000033683.8
ribosomal protein S4, X-linked
chr13_+_21995906 1.57 ENSMUST00000104941.4
H4 clustered histone 17
chr1_-_107206091 1.57 ENSMUST00000166100.2
ENSMUST00000027565.5
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3B
serine (or cysteine) peptidase inhibitor, clade B, member 3C
chr1_+_178015287 1.56 ENSMUST00000159284.2
desumoylating isopeptidase 2
chr19_+_32573182 1.55 ENSMUST00000235594.2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr16_+_33614715 1.54 ENSMUST00000023520.7
mucin 13, epithelial transmembrane
chr6_+_70680515 1.53 ENSMUST00000103404.2
immunoglobulin kappa variable 3-1
chr10_-_12743915 1.52 ENSMUST00000219584.2
utrophin
chr16_+_35861554 1.51 ENSMUST00000042203.10
WD repeat domain 5B
chr9_-_50528727 1.50 ENSMUST00000131351.8
ENSMUST00000171462.8
NKAP domain containing 1
chr3_-_10366229 1.50 ENSMUST00000119761.2
ENSMUST00000029043.13
fatty acid binding protein 12
chr1_+_40123858 1.49 ENSMUST00000027243.13
interleukin 1 receptor, type II
chr14_-_30645503 1.49 ENSMUST00000227995.2
inter-alpha trypsin inhibitor, heavy chain 3
chr6_-_69584812 1.48 ENSMUST00000103359.3
immunoglobulin kappa variable 4-55
chr6_-_68887957 1.48 ENSMUST00000200454.2
immunoglobulin kappa variable 4-86
chr5_+_117258185 1.46 ENSMUST00000111978.8
TAO kinase 3
chr8_+_95472218 1.46 ENSMUST00000034231.4
chemokine (C-C motif) ligand 22
chr3_-_136031799 1.44 ENSMUST00000196159.5
ENSMUST00000041577.13
B cell scaffold protein with ankyrin repeats 1
chr14_+_59438658 1.44 ENSMUST00000173547.8
ENSMUST00000043227.13
ENSMUST00000022551.14
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chr19_+_46120327 1.44 ENSMUST00000043739.6
ENSMUST00000237098.2
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3
chr2_-_62476487 1.44 ENSMUST00000112459.4
ENSMUST00000028259.12
interferon induced with helicase C domain 1
chr11_-_70350783 1.42 ENSMUST00000019064.9
chemokine (C-X-C motif) ligand 16
chr14_-_31362835 1.42 ENSMUST00000167066.8
ENSMUST00000127204.9
2-hydroxyacyl-CoA lyase 1
chr18_+_67338437 1.39 ENSMUST00000210564.3
charged multivesicular body protein 1B
chr3_+_92325386 1.38 ENSMUST00000029533.3
small proline-rich protein 2J, pseudogene
chr6_-_130044234 1.37 ENSMUST00000119096.2
killer cell lectin-like receptor, subfamily A, member 4
chr7_+_27198740 1.36 ENSMUST00000098644.9
ENSMUST00000108355.2
ENSMUST00000238936.2
periaxin
chr8_+_79235946 1.35 ENSMUST00000209490.2
ENSMUST00000034111.10
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr14_+_40853734 1.34 ENSMUST00000022314.10
ENSMUST00000170719.2
surfactant associated protein A1
chr3_+_116653113 1.32 ENSMUST00000040260.11
ferric-chelate reductase 1
chr10_-_128640232 1.30 ENSMUST00000051011.14
transmembrane protein 198b
chr6_+_65502344 1.28 ENSMUST00000212375.2
TNFAIP3 interacting protein 3
chr3_-_16060491 1.26 ENSMUST00000108347.3
predicted gene 5150
chr16_+_38383154 1.26 ENSMUST00000171687.8
ENSMUST00000002924.15
transmembrane protein 39a
chr2_-_126342551 1.26 ENSMUST00000129187.2
ATPase, class I, type 8B, member 4
chr3_-_16060545 1.25 ENSMUST00000194367.6
predicted gene 5150
chr18_-_66155651 1.25 ENSMUST00000143990.2
lectin, mannose-binding, 1
chr9_+_108880158 1.23 ENSMUST00000198708.5
shisa family member 5
chr14_-_30645711 1.22 ENSMUST00000006697.17
inter-alpha trypsin inhibitor, heavy chain 3
chr1_+_173248104 1.21 ENSMUST00000173023.2
absent in melanoma 2
chr11_+_67061837 1.21 ENSMUST00000170159.8
myosin, heavy polypeptide 2, skeletal muscle, adult
chr6_-_124710084 1.20 ENSMUST00000112484.10
protein tyrosine phosphatase, non-receptor type 6
chr3_+_142406827 1.20 ENSMUST00000044392.11
ENSMUST00000199519.5
kynurenine aminotransferase 3
chr4_+_62581857 1.20 ENSMUST00000126338.2
regulator of G-protein signaling 3
chrX_-_107877909 1.20 ENSMUST00000101283.4
ENSMUST00000150434.8
bromodomain and WD repeat domain containing 3
chr11_+_95275458 1.19 ENSMUST00000021243.16
ENSMUST00000146556.2
solute carrier family 35, member B1
chr19_+_44980565 1.19 ENSMUST00000179305.2
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr3_+_142406787 1.18 ENSMUST00000106218.8
kynurenine aminotransferase 3
chr9_+_57604895 1.17 ENSMUST00000034865.6
cytochrome P450, family 1, subfamily a, polypeptide 1
chr13_+_112604037 1.17 ENSMUST00000183868.8
interleukin 6 signal transducer
chr14_+_54421231 1.15 ENSMUST00000103706.2
T cell receptor alpha joining 35
chr11_+_67061908 1.14 ENSMUST00000018641.8
myosin, heavy polypeptide 2, skeletal muscle, adult
chr5_-_65248962 1.11 ENSMUST00000212080.2
transmembrane protein 156
chr9_-_48516447 1.11 ENSMUST00000034808.12
ENSMUST00000119426.2
nicotinamide N-methyltransferase
chr9_-_14815163 1.10 ENSMUST00000069408.10
IZUMO1 receptor, JUNO
chr7_+_27147403 1.10 ENSMUST00000037399.16
ENSMUST00000108358.8
biliverdin reductase B (flavin reductase (NADPH))
chr6_-_68887922 1.09 ENSMUST00000103337.3
immunoglobulin kappa variable 4-86
chr18_-_78100610 1.09 ENSMUST00000170760.3
sialic acid binding Ig-like lectin 15
chr17_+_24768808 1.09 ENSMUST00000228550.2
ENSMUST00000035565.5
polycystin 1, transient receptor poteintial channel interacting
chr6_-_113717689 1.09 ENSMUST00000032440.6
SEC13 homolog, nuclear pore and COPII coat complex component
chr3_-_108053396 1.09 ENSMUST00000000001.5
guanine nucleotide binding protein (G protein), alpha inhibiting 3
chr12_-_36206780 1.09 ENSMUST00000223382.2
ENSMUST00000020856.6
basic leucine zipper and W2 domains 2
chr7_+_27147475 1.09 ENSMUST00000133750.8
biliverdin reductase B (flavin reductase (NADPH))
chr6_+_65502292 1.08 ENSMUST00000212402.2
TNFAIP3 interacting protein 3
chr9_+_38630317 1.07 ENSMUST00000129598.2
von Willebrand factor A domain containing 5A
chr6_+_139564196 1.06 ENSMUST00000188066.2
ENSMUST00000190962.7
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr14_-_87378641 1.05 ENSMUST00000168889.3
ENSMUST00000022599.14
diaphanous related formin 3
chr6_+_15727798 1.05 ENSMUST00000128849.3
MyoD family inhibitor domain containing
chr4_-_117013396 1.05 ENSMUST00000102696.5
ribosomal protein S8
chr6_-_69020489 1.05 ENSMUST00000103342.4
immunoglobulin kappa variable 4-79
chr12_+_21366386 1.04 ENSMUST00000076813.8
ENSMUST00000221693.2
ENSMUST00000223345.2
ENSMUST00000222344.2
isoamyl acetate-hydrolyzing esterase 1 homolog
chr11_-_114825089 1.04 ENSMUST00000149663.4
ENSMUST00000239005.2
ENSMUST00000106581.5
CD300 molecule like family member B
chr8_+_79236051 0.99 ENSMUST00000209992.2
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr14_+_54431947 0.98 ENSMUST00000103715.2
T cell receptor alpha joining 26
chr11_+_115044966 0.98 ENSMUST00000021076.6
RAB37, member RAS oncogene family
chr13_+_55862437 0.98 ENSMUST00000021959.11
thioredoxin domain containing 15
chr16_+_33201227 0.98 ENSMUST00000232023.2
zinc finger protein 148
chrX_-_133012457 0.97 ENSMUST00000159259.3
ENSMUST00000113275.10
NADPH oxidase 1
chr4_-_137137088 0.97 ENSMUST00000024200.7
chymotrypsin-like elastase family, member 3A
chr9_+_62249730 0.97 ENSMUST00000156461.2
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr9_+_62249341 0.94 ENSMUST00000135395.8
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr5_-_65248927 0.94 ENSMUST00000043352.8
transmembrane protein 156
chr7_+_19738020 0.94 ENSMUST00000137183.9
NLR family, pyrin domain containing 9B
chr1_-_165830187 0.94 ENSMUST00000184643.8
ENSMUST00000160908.8
ENSMUST00000027850.15
ENSMUST00000160260.9
POU domain, class 2, transcription factor 1
chr3_-_136031723 0.94 ENSMUST00000198206.2
B cell scaffold protein with ankyrin repeats 1
chr10_+_79986988 0.94 ENSMUST00000146516.8
ENSMUST00000144526.2
midnolin
chrX_+_13527592 0.93 ENSMUST00000053659.2
G protein-coupled receptor 82
chr8_-_70975813 0.92 ENSMUST00000121623.8
ENSMUST00000093456.12
ENSMUST00000118850.8
KxDL motif containing 1
chr5_-_137869969 0.92 ENSMUST00000196162.5
paired immunoglobin-like type 2 receptor beta 2
chr16_+_48692976 0.91 ENSMUST00000065666.6
resistin like gamma
chr19_-_41790458 0.91 ENSMUST00000026150.15
ENSMUST00000163265.9
ENSMUST00000177495.2
Rho GTPase activating protein 19
chr11_+_96355475 0.91 ENSMUST00000107663.4
src family associated phosphoprotein 1
chr3_-_144555062 0.90 ENSMUST00000159989.2
chloride channel accessory 3B
chr16_+_59292138 0.90 ENSMUST00000023407.12
ENSMUST00000120667.2
ENSMUST00000120674.8
ribosomal oxygenase 2
chr7_-_80053063 0.89 ENSMUST00000147150.2
furin (paired basic amino acid cleaving enzyme)
chr8_-_70963202 0.89 ENSMUST00000125184.8
ubiquitin A-52 residue ribosomal protein fusion product 1
chr10_-_75616788 0.89 ENSMUST00000173512.2
ENSMUST00000173537.2
predicted gene 20441
glutathione S-transferase, theta 3
chr5_-_137529465 0.88 ENSMUST00000150063.9
guanine nucleotide binding protein (G protein), beta 2
chr6_+_30541581 0.88 ENSMUST00000096066.5
carboxypeptidase A2, pancreatic
chr1_-_85239791 0.87 ENSMUST00000162421.2
RIKEN cDNA C130026I21 gene
chr18_+_4993795 0.87 ENSMUST00000153016.8
supervillin
chr2_+_122146153 0.86 ENSMUST00000099461.4
dual oxidase 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 16.5 GO:0014016 neuroblast differentiation(GO:0014016)
2.1 6.4 GO:1902617 response to fluoride(GO:1902617)
2.0 9.9 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
1.3 5.0 GO:0046356 acetyl-CoA catabolic process(GO:0046356)
1.2 8.7 GO:1903232 platelet dense granule organization(GO:0060155) phagosome acidification(GO:0090383) melanosome assembly(GO:1903232)
1.2 3.6 GO:0032618 interleukin-15 production(GO:0032618)
1.0 2.9 GO:0015860 purine nucleoside transmembrane transport(GO:0015860) nucleoside transmembrane transport(GO:1901642)
0.6 2.5 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.6 2.9 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.6 1.2 GO:0070104 negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.6 1.7 GO:0009087 methionine catabolic process(GO:0009087)
0.6 1.7 GO:0030887 positive regulation of myeloid dendritic cell activation(GO:0030887)
0.5 2.2 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296) interleukin-4-mediated signaling pathway(GO:0035771)
0.5 3.3 GO:0007527 adult somatic muscle development(GO:0007527)
0.5 1.8 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.4 4.0 GO:0006572 tyrosine catabolic process(GO:0006572)
0.4 1.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.4 2.1 GO:1990743 protein sialylation(GO:1990743)
0.4 1.2 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.4 1.6 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.4 1.5 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.4 1.1 GO:0060854 patterning of lymph vessels(GO:0060854)
0.3 2.0 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.3 2.0 GO:0035549 interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549)
0.3 0.9 GO:0030961 peptidyl-arginine hydroxylation(GO:0030961)
0.3 1.2 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
0.3 2.3 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.3 0.8 GO:0006583 melanin biosynthetic process from tyrosine(GO:0006583)
0.3 0.8 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.3 2.2 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.3 2.4 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.2 4.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.2 2.0 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.2 1.9 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.2 1.6 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.2 0.9 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.2 1.6 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.2 1.4 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.2 0.7 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416)
0.2 0.9 GO:0090472 dibasic protein processing(GO:0090472)
0.2 1.5 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.2 0.9 GO:0042335 cuticle development(GO:0042335)
0.2 0.9 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) histone H2A K63-linked deubiquitination(GO:0070537)
0.2 14.6 GO:0018149 peptide cross-linking(GO:0018149)
0.2 1.8 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.2 3.6 GO:2000675 egg activation(GO:0007343) negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.2 1.6 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.2 0.6 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.2 0.6 GO:0014732 skeletal muscle atrophy(GO:0014732)
0.2 1.0 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.2 0.6 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.2 1.9 GO:0019660 glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.2 2.4 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.2 2.1 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.2 0.9 GO:0006566 threonine metabolic process(GO:0006566)
0.2 2.9 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.2 0.5 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.2 1.8 GO:0042637 catagen(GO:0042637)
0.2 0.5 GO:0034769 basement membrane disassembly(GO:0034769)
0.2 0.6 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.2 1.2 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 2.4 GO:0070189 kynurenine metabolic process(GO:0070189)
0.1 1.3 GO:0008228 opsonization(GO:0008228)
0.1 2.4 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.1 2.4 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.6 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 1.4 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 1.1 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 1.6 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.9 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.5 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.1 3.7 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 1.4 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.7 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 5.2 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.9 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 1.4 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 16.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.4 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.1 1.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.5 GO:1905068 positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 7.3 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.1 2.0 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 0.6 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.1 0.6 GO:0048496 determination of pancreatic left/right asymmetry(GO:0035469) maintenance of organ identity(GO:0048496)
0.1 6.6 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 1.4 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.1 1.2 GO:0070269 pyroptosis(GO:0070269)
0.1 21.1 GO:0002377 immunoglobulin production(GO:0002377)
0.1 1.8 GO:0031424 keratinization(GO:0031424)
0.1 1.1 GO:2001204 regulation of osteoclast development(GO:2001204)
0.1 0.9 GO:0033504 floor plate development(GO:0033504)
0.1 0.4 GO:0051572 negative regulation of histone H3-K4 methylation(GO:0051572)
0.1 3.3 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 1.5 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 0.4 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1 0.3 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 0.6 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
0.1 0.3 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1 1.8 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 1.1 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 1.0 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 5.9 GO:0034341 response to interferon-gamma(GO:0034341)
0.1 0.5 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.4 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0 0.1 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.0 0.8 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.7 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.4 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.5 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 1.0 GO:0002446 neutrophil mediated immunity(GO:0002446)
0.0 0.1 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
0.0 8.6 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.0 1.0 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 1.1 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.6 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.5 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.6 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 1.6 GO:0042755 eating behavior(GO:0042755)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.8 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 3.8 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.9 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 2.2 GO:1900046 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.0 1.6 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.6 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 1.1 GO:0046039 GTP metabolic process(GO:0046039)
0.0 1.2 GO:0050919 negative chemotaxis(GO:0050919)
0.0 2.8 GO:0050715 positive regulation of cytokine secretion(GO:0050715)
0.0 0.4 GO:0021554 optic nerve development(GO:0021554)
0.0 0.2 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 2.0 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.3 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:0035745 CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745)
0.0 0.3 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 1.0 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.9 GO:0032418 lysosome localization(GO:0032418)
0.0 0.9 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.1 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.3 GO:0006379 mRNA cleavage(GO:0006379)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 8.7 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
1.0 16.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.4 6.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.4 1.2 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.3 18.6 GO:0001533 cornified envelope(GO:0001533)
0.3 1.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.3 2.4 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 1.1 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.2 3.3 GO:0070938 contractile ring(GO:0070938)
0.2 0.6 GO:0097543 ciliary inversin compartment(GO:0097543)
0.2 2.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.9 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 7.1 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.6 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.1 16.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.0 GO:0071438 invadopodium membrane(GO:0071438)
0.1 1.4 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 2.0 GO:0042101 T cell receptor complex(GO:0042101)
0.1 1.1 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.5 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.6 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.6 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 2.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.5 GO:0098536 deuterosome(GO:0098536)
0.1 0.4 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.1 0.9 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 0.6 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 1.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 3.0 GO:0005771 multivesicular body(GO:0005771)
0.1 0.6 GO:0061689 tricellular tight junction(GO:0061689)
0.1 1.2 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.1 0.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 1.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 3.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.8 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.3 GO:0042629 mast cell granule(GO:0042629)
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 1.4 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 3.7 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.8 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.1 GO:0042588 zymogen granule(GO:0042588)
0.0 1.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.6 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 4.1 GO:0072562 blood microparticle(GO:0072562)
0.0 2.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.3 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 3.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:0044754 autolysosome(GO:0044754)
0.0 3.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 43.1 GO:0005615 extracellular space(GO:0005615)
0.0 0.9 GO:0043034 costamere(GO:0043034)
0.0 6.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.4 GO:0070822 Sin3-type complex(GO:0070822)
0.0 1.0 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.3 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.6 GO:0016235 aggresome(GO:0016235)
0.0 1.6 GO:0031526 brush border membrane(GO:0031526)
0.0 0.9 GO:0005604 basement membrane(GO:0005604)
0.0 2.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 2.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 16.5 GO:0003990 acetylcholinesterase activity(GO:0003990)
2.9 8.7 GO:0036461 BLOC-2 complex binding(GO:0036461)
1.6 6.4 GO:0004063 aryldialkylphosphatase activity(GO:0004063)
1.3 4.0 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
1.2 6.2 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
1.0 4.9 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
1.0 2.9 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.9 3.6 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.7 2.2 GO:0042602 riboflavin reductase (NADPH) activity(GO:0042602)
0.7 2.0 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.6 1.7 GO:0032394 MHC class Ib receptor activity(GO:0032394)
0.5 2.1 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
0.5 3.6 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.5 2.4 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.4 1.7 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.4 1.2 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.4 1.6 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.4 1.5 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.4 1.8 GO:0030984 kininogen binding(GO:0030984)
0.4 3.3 GO:0016936 galactoside binding(GO:0016936)
0.4 2.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.3 1.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.2 9.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 0.9 GO:0070905 serine binding(GO:0070905)
0.2 1.4 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.2 1.1 GO:0097643 amylin receptor activity(GO:0097643)
0.2 0.5 GO:0033680 ATP-dependent DNA/RNA helicase activity(GO:0033680) triplex DNA binding(GO:0045142)
0.2 3.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.2 1.9 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 0.5 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.2 1.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.2 2.0 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.2 1.0 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.2 0.6 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.1 3.7 GO:0051861 glycolipid binding(GO:0051861)
0.1 1.6 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.4 GO:0019959 interleukin-8 binding(GO:0019959)
0.1 0.6 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 1.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 16.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.8 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 1.4 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 2.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.7 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 3.3 GO:0017166 vinculin binding(GO:0017166)
0.1 1.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 2.9 GO:0005542 folic acid binding(GO:0005542)
0.1 1.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.8 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 0.7 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 1.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.3 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 1.9 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 1.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 10.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 1.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 1.0 GO:0030957 Tat protein binding(GO:0030957)
0.1 1.2 GO:0005537 mannose binding(GO:0005537)
0.1 0.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.9 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.4 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 6.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.7 GO:0070628 proteasome binding(GO:0070628)
0.0 2.3 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.8 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 2.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.8 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 2.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.2 GO:0005047 signal recognition particle binding(GO:0005047) endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 1.2 GO:0070330 aromatase activity(GO:0070330)
0.0 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.5 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 1.2 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.4 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.8 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 0.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 2.4 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.9 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 3.6 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.6 GO:0042608 T cell receptor binding(GO:0042608)
0.0 2.2 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 1.2 GO:0050699 WW domain binding(GO:0050699)
0.0 1.5 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.3 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 1.6 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 4.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 5.9 GO:0030246 carbohydrate binding(GO:0030246)
0.0 2.7 GO:0005179 hormone activity(GO:0005179)
0.0 1.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.7 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 2.4 GO:0042393 histone binding(GO:0042393)
0.0 1.8 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.2 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 10.4 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.4 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 4.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 8.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 2.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 0.4 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 6.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 6.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 14.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 3.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 1.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 2.2 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 1.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.5 PID IL1 PATHWAY IL1-mediated signaling events
0.0 10.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.2 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.2 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 1.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 2.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.1 PID CDC42 PATHWAY CDC42 signaling events
0.0 2.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 1.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 2.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 0.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.5 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 18.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.5 7.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.4 1.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.4 9.9 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.2 0.5 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 6.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 1.9 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 1.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 1.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 3.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 0.5 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 7.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 1.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.0 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 2.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 0.9 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 1.4 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 1.2 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 1.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 3.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 0.9 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 0.8 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 3.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 1.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 1.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 2.1 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.8 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 2.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 3.6 REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0 1.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 1.5 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.6 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.4 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.6 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 1.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 2.1 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.4 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 1.1 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter