Project

PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

Navigation
Downloads

Results for Onecut1_Cux2

Z-value: 1.84

Motif logo

logo of logo of

Transcription factors associated with Onecut1_Cux2

Gene Symbol Gene ID Gene Info
Onecut1
ENSMUSG00000043013.11 Onecut1
Cux2
ENSMUSG00000042589.19 Cux2
Cux2
ENSMUSG00000042589.19 Cux2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Onecut1mm39_v1_chr9_+_74769166_747692030.883.7e-24Click!
Cux2mm39_v1_chr5_-_122188165_1221882210.318.7e-03Click!

Activity profile of Onecut1_Cux2 motif

Sorted Z-values of Onecut1_Cux2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Onecut1_Cux2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr4_-_63072367 47.33 ENSMUST00000030041.5
Ambp
alpha 1 microglobulin/bikunin precursor
chr16_+_22769822 45.39 ENSMUST00000023590.9
Hrg
histidine-rich glycoprotein
chr4_-_104733580 41.68 ENSMUST00000064873.9
ENSMUST00000106808.10
ENSMUST00000048947.15
C8a
complement component 8, alpha polypeptide
chr1_+_172525613 38.21 ENSMUST00000038495.5
Crp
C-reactive protein, pentraxin-related
chr16_+_22769844 37.45 ENSMUST00000232422.2
Hrg
histidine-rich glycoprotein
chr3_+_28752050 32.46 ENSMUST00000029240.14
Slc2a2
solute carrier family 2 (facilitated glucose transporter), member 2
chr6_+_121323577 27.44 ENSMUST00000032200.16
Slc6a12
solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
chr11_+_78389913 22.69 ENSMUST00000017488.5
Vtn
vitronectin
chr3_+_146302832 22.68 ENSMUST00000029837.14
ENSMUST00000147409.2
ENSMUST00000121133.2
Uox
urate oxidase
chr15_-_60793115 19.86 ENSMUST00000096418.5
A1bg
alpha-1-B glycoprotein
chr14_-_30665232 17.77 ENSMUST00000006704.17
ENSMUST00000163118.2
Itih1
inter-alpha trypsin inhibitor, heavy chain 1
chr19_-_38113696 17.15 ENSMUST00000025951.14
ENSMUST00000237287.2
Rbp4
retinol binding protein 4, plasma
chr1_+_88334678 15.96 ENSMUST00000027518.12
Spp2
secreted phosphoprotein 2
chr6_-_23132977 14.93 ENSMUST00000031707.14
Aass
aminoadipate-semialdehyde synthase
chr15_-_78352801 13.64 ENSMUST00000229124.2
ENSMUST00000230226.2
ENSMUST00000017086.5
Tmprss6
transmembrane serine protease 6
chr11_-_59927688 11.97 ENSMUST00000102692.10
Pemt
phosphatidylethanolamine N-methyltransferase
chrX_+_100420873 11.24 ENSMUST00000052130.14
Gjb1
gap junction protein, beta 1
chr2_-_147888816 10.91 ENSMUST00000172928.2
ENSMUST00000047315.10
Foxa2
forkhead box A2
chr11_+_101258368 9.99 ENSMUST00000019469.3
G6pc
glucose-6-phosphatase, catalytic
chr15_-_96929086 9.58 ENSMUST00000230086.2
Slc38a4
solute carrier family 38, member 4
chr7_+_43856724 9.40 ENSMUST00000077354.5
Klk1b4
kallikrein 1-related pepidase b4
chr4_-_46991842 8.71 ENSMUST00000107749.4
Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr3_-_146302343 7.89 ENSMUST00000029836.9
Dnase2b
deoxyribonuclease II beta
chr2_-_84605764 7.78 ENSMUST00000111641.2
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr2_-_84605732 7.54 ENSMUST00000023994.10
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr14_+_68321302 7.15 ENSMUST00000022639.8
Nefl
neurofilament, light polypeptide
chr19_+_56276343 6.97 ENSMUST00000095948.11
Habp2
hyaluronic acid binding protein 2
chr14_-_4488167 6.88 ENSMUST00000022304.12
Thrb
thyroid hormone receptor beta
chr8_+_127790772 5.95 ENSMUST00000079777.12
ENSMUST00000160272.8
ENSMUST00000162907.8
ENSMUST00000162536.8
ENSMUST00000026921.13
ENSMUST00000162665.8
ENSMUST00000162602.8
ENSMUST00000160581.8
ENSMUST00000161355.8
ENSMUST00000162531.8
ENSMUST00000160766.8
ENSMUST00000159537.8
Pard3
par-3 family cell polarity regulator
chr10_+_29019645 5.83 ENSMUST00000092629.4
Soga3
SOGA family member 3
chr9_-_114673158 5.37 ENSMUST00000047013.4
Cmtm8
CKLF-like MARVEL transmembrane domain containing 8
chr15_+_54975713 5.23 ENSMUST00000096433.10
Deptor
DEP domain containing MTOR-interacting protein
chr5_+_130413532 4.82 ENSMUST00000202728.2
Caln1
calneuron 1
chr3_+_5283577 4.70 ENSMUST00000175866.8
Zfhx4
zinc finger homeodomain 4
chr1_+_191449946 4.65 ENSMUST00000133076.7
ENSMUST00000110855.8
Lpgat1
lysophosphatidylglycerol acyltransferase 1
chr3_+_5283606 4.65 ENSMUST00000026284.13
Zfhx4
zinc finger homeodomain 4
chr10_-_128237087 4.63 ENSMUST00000042666.13
Slc39a5
solute carrier family 39 (metal ion transporter), member 5
chr18_+_36098090 4.61 ENSMUST00000176873.8
ENSMUST00000177432.8
ENSMUST00000175734.2
Psd2
pleckstrin and Sec7 domain containing 2
chr15_+_54975814 4.30 ENSMUST00000100660.11
Deptor
DEP domain containing MTOR-interacting protein
chr12_+_55646209 4.27 ENSMUST00000051857.5
Insm2
insulinoma-associated 2
chr6_-_16898440 4.07 ENSMUST00000031533.11
Tfec
transcription factor EC
chr9_+_59496571 4.04 ENSMUST00000121266.8
ENSMUST00000118164.3
Celf6
CUGBP, Elav-like family member 6
chr5_-_122188165 3.77 ENSMUST00000154139.8
Cux2
cut-like homeobox 2
chr9_-_29874401 3.42 ENSMUST00000075069.11
Ntm
neurotrimin
chr1_-_75195127 3.38 ENSMUST00000079464.13
Tuba4a
tubulin, alpha 4A
chr19_-_37155410 3.28 ENSMUST00000133988.2
Cpeb3
cytoplasmic polyadenylation element binding protein 3
chr5_-_122187884 3.21 ENSMUST00000111752.10
Cux2
cut-like homeobox 2
chrX_-_42363663 3.18 ENSMUST00000016294.8
Tenm1
teneurin transmembrane protein 1
chr12_-_25146078 3.16 ENSMUST00000222667.2
ENSMUST00000020974.7
Id2
inhibitor of DNA binding 2
chr10_-_63926044 3.07 ENSMUST00000105439.2
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr8_-_32408786 2.84 ENSMUST00000239000.2
Nrg1
neuregulin 1
chr5_+_3646066 2.67 ENSMUST00000006061.13
ENSMUST00000121291.8
ENSMUST00000142516.2
Pex1
peroxisomal biogenesis factor 1
chr3_-_79439181 2.60 ENSMUST00000239298.2
Fnip2
folliculin interacting protein 2
chr5_+_3646355 2.51 ENSMUST00000195894.2
Pex1
peroxisomal biogenesis factor 1
chr15_+_22549108 2.42 ENSMUST00000163361.8
Cdh18
cadherin 18
chrM_+_14138 2.21 ENSMUST00000082421.1
mt-Cytb
mitochondrially encoded cytochrome b
chr15_+_92059224 2.21 ENSMUST00000068378.6
Cntn1
contactin 1
chr3_+_101917455 2.17 ENSMUST00000066187.6
ENSMUST00000198675.2
Nhlh2
nescient helix loop helix 2
chr1_-_13197387 2.11 ENSMUST00000047577.7
Prdm14
PR domain containing 14
chr16_-_37205302 2.06 ENSMUST00000114781.8
ENSMUST00000114780.8
Stxbp5l
syntaxin binding protein 5-like
chr8_+_59364789 2.04 ENSMUST00000062978.7
BC030500
cDNA sequence BC030500
chr16_-_37205277 1.99 ENSMUST00000114787.8
ENSMUST00000114782.8
ENSMUST00000114775.8
Stxbp5l
syntaxin binding protein 5-like
chr7_+_67297152 1.90 ENSMUST00000032774.16
ENSMUST00000107471.8
Ttc23
tetratricopeptide repeat domain 23
chr17_-_54605479 1.77 ENSMUST00000233758.2
Slc5a7
solute carrier family 5 (choline transporter), member 7
chr3_+_94280101 1.76 ENSMUST00000029795.10
Rorc
RAR-related orphan receptor gamma
chr4_-_97472844 1.74 ENSMUST00000107067.8
ENSMUST00000107068.9
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr14_-_51279318 1.61 ENSMUST00000064214.4
Rnase9
ribonuclease, RNase A family, 9 (non-active)
chr18_-_72484126 1.58 ENSMUST00000114943.11
Dcc
deleted in colorectal carcinoma
chr5_+_63806451 1.42 ENSMUST00000159584.3
Nwd2
NACHT and WD repeat domain containing 2
chr3_+_125197722 1.42 ENSMUST00000173932.8
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr8_+_56747613 1.37 ENSMUST00000034026.10
Hpgd
hydroxyprostaglandin dehydrogenase 15 (NAD)
chr4_+_117706559 1.35 ENSMUST00000163288.2
Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr8_-_32408380 1.31 ENSMUST00000208497.3
ENSMUST00000207584.3
Nrg1
neuregulin 1
chr11_+_117375194 1.31 ENSMUST00000092394.4
Gm11733
predicted gene 11733
chr7_+_67305162 1.28 ENSMUST00000107470.2
Ttc23
tetratricopeptide repeat domain 23
chr14_-_55329734 1.27 ENSMUST00000036328.9
Zfhx2
zinc finger homeobox 2
chr4_-_110149916 1.26 ENSMUST00000106601.8
Elavl4
ELAV like RNA binding protein 4
chr4_+_117706390 1.23 ENSMUST00000132043.9
ENSMUST00000169990.8
Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr13_+_93441307 1.20 ENSMUST00000080127.12
Homer1
homer scaffolding protein 1
chr5_-_130413472 1.09 ENSMUST00000063656.7
A330070K13Rik
RIKEN cDNA A330070K13 gene
chr6_+_40468167 1.02 ENSMUST00000064932.6
Tas2r137
taste receptor, type 2, member 137
chr3_-_33136153 1.01 ENSMUST00000108225.10
Pex5l
peroxisomal biogenesis factor 5-like
chr2_+_89808124 0.88 ENSMUST00000061830.2
Olfr1260
olfactory receptor 1260
chrX_-_140979913 0.88 ENSMUST00000042530.4
Gucy2f
guanylate cyclase 2f
chr2_+_163444214 0.87 ENSMUST00000171696.8
ENSMUST00000109408.10
Ttpal
tocopherol (alpha) transfer protein-like
chr8_+_23114035 0.86 ENSMUST00000033936.8
Dkk4
dickkopf WNT signaling pathway inhibitor 4
chrX_+_55917903 0.83 ENSMUST00000153784.8
Adgrg4
adhesion G protein-coupled receptor G4
chr19_+_59207646 0.82 ENSMUST00000065204.8
Kcnk18
potassium channel, subfamily K, member 18
chr7_+_75498058 0.81 ENSMUST00000171155.4
ENSMUST00000092073.11
ENSMUST00000206019.2
ENSMUST00000205612.2
ENSMUST00000205887.2
Klhl25
kelch-like 25
chr2_-_168608949 0.74 ENSMUST00000075044.10
Sall4
spalt like transcription factor 4
chr7_-_105460172 0.72 ENSMUST00000033170.7
ENSMUST00000176498.2
ENSMUST00000176887.2
ENSMUST00000124482.3
Mrpl17
mitochondrial ribosomal protein L17
chr19_+_4042752 0.71 ENSMUST00000041871.9
Tbx10
T-box 10
chr19_+_55882942 0.71 ENSMUST00000142291.8
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr18_-_72484082 0.70 ENSMUST00000073379.6
Dcc
deleted in colorectal carcinoma
chr13_-_54836059 0.64 ENSMUST00000122935.2
ENSMUST00000128257.8
Rnf44
ring finger protein 44
chr11_+_110914678 0.62 ENSMUST00000150902.8
ENSMUST00000178798.2
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
chr5_-_3646071 0.60 ENSMUST00000121877.3
Rbm48
RNA binding motif protein 48
chr18_+_37063237 0.44 ENSMUST00000193839.6
ENSMUST00000070797.7
Pcdha1
protocadherin alpha 1
chr19_+_31060237 0.43 ENSMUST00000066039.8
Cstf2t
cleavage stimulation factor, 3' pre-RNA subunit 2, tau
chr11_-_24025054 0.41 ENSMUST00000068360.2
A830031A19Rik
RIKEN cDNA A830031A19 gene
chrX_-_48980360 0.38 ENSMUST00000217355.3
Olfr1322
olfactory receptor 1322
chr11_-_33942981 0.37 ENSMUST00000238903.2
Kcnip1
Kv channel-interacting protein 1
chr15_-_8739893 0.37 ENSMUST00000157065.2
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr18_+_69652880 0.33 ENSMUST00000200813.4
Tcf4
transcription factor 4
chr7_-_102238026 0.32 ENSMUST00000098224.3
Olfr551
olfactory receptor 551
chr3_-_79749949 0.29 ENSMUST00000029568.7
Tmem144
transmembrane protein 144
chr11_-_120515799 0.27 ENSMUST00000106183.3
ENSMUST00000080202.12
Sirt7
sirtuin 7
chr12_-_84745388 0.25 ENSMUST00000221905.2
ENSMUST00000222422.2
ENSMUST00000095550.4
Syndig1l
synapse differentiation inducing 1 like
chr10_-_118179160 0.24 ENSMUST00000218329.2
Gm9046
predicted gene 9046
chrX_+_133305529 0.22 ENSMUST00000113224.9
ENSMUST00000113226.2
Drp2
dystrophin related protein 2
chr14_+_54436247 0.21 ENSMUST00000103720.2
Traj21
T cell receptor alpha joining 21
chr5_-_3646540 0.19 ENSMUST00000042753.14
Rbm48
RNA binding motif protein 48
chr1_-_60137294 0.17 ENSMUST00000141417.3
ENSMUST00000122038.8
Wdr12
WD repeat domain 12
chr16_+_19302444 0.17 ENSMUST00000216465.2
ENSMUST00000213531.2
Olfr166
olfactory receptor 166
chr7_-_102805563 0.13 ENSMUST00000218483.2
Olfr589
olfactory receptor 589
chr2_+_163444248 0.09 ENSMUST00000152135.8
Ttpal
tocopherol (alpha) transfer protein-like

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
27.6 82.8 GO:0097037 heme export(GO:0097037)
6.5 32.5 GO:0070837 dehydroascorbic acid transport(GO:0070837)
5.1 15.3 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
5.0 14.9 GO:0006553 lysine metabolic process(GO:0006553)
4.8 38.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
4.6 27.4 GO:0009992 cellular water homeostasis(GO:0009992)
3.6 10.9 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
3.4 17.1 GO:0048807 female genitalia morphogenesis(GO:0048807)
3.2 47.3 GO:0018298 protein-chromophore linkage(GO:0018298)
2.5 41.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
2.4 7.1 GO:0033693 neurofilament bundle assembly(GO:0033693)
1.7 22.7 GO:0097421 smooth muscle cell-matrix adhesion(GO:0061302) liver regeneration(GO:0097421)
1.7 5.2 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
1.7 12.0 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
1.5 32.7 GO:0046415 urate metabolic process(GO:0046415)
1.1 6.9 GO:0007621 negative regulation of female receptivity(GO:0007621)
1.1 3.3 GO:1900247 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
1.1 3.2 GO:0001966 thigmotaxis(GO:0001966)
0.9 11.2 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.9 4.6 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.9 2.6 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.9 6.0 GO:0003383 apical constriction(GO:0003383)
0.7 13.6 GO:0097264 self proteolysis(GO:0097264)
0.6 1.8 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.5 5.4 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.5 2.1 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.5 2.3 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.4 4.2 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.4 9.5 GO:0045792 negative regulation of cell size(GO:0045792)
0.4 17.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.3 7.9 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.3 2.2 GO:0033762 response to glucagon(GO:0033762)
0.3 9.4 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.3 7.0 GO:0007614 short-term memory(GO:0007614)
0.3 1.6 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.2 8.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 1.8 GO:0072615 interleukin-17 secretion(GO:0072615)
0.2 3.1 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 1.0 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.1 7.7 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 16.0 GO:0046849 bone remodeling(GO:0046849)
0.1 4.6 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.9 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.1 0.7 GO:0044334 canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.1 3.3 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.1 1.4 GO:0007567 parturition(GO:0007567)
0.1 4.0 GO:0071625 vocalization behavior(GO:0071625)
0.1 0.3 GO:0045896 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.1 4.1 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.1 2.2 GO:0044705 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 4.1 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.8 GO:0071435 potassium ion export(GO:0071435)
0.0 0.4 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 3.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.8 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 0.9 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 1.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.4 GO:0045760 positive regulation of action potential(GO:0045760)
0.0 2.2 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.7 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.0 0.6 GO:0010107 potassium ion import(GO:0010107)
0.0 2.6 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 3.9 GO:0010506 regulation of autophagy(GO:0010506)
0.0 0.3 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.8 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 1.3 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 2.7 GO:0010977 negative regulation of neuron projection development(GO:0010977)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
27.6 82.8 GO:0061474 phagolysosome membrane(GO:0061474)
4.6 41.7 GO:0005579 membrane attack complex(GO:0005579)
3.2 22.7 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
1.8 7.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
1.7 8.7 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.7 6.0 GO:0033269 internode region of axon(GO:0033269)
0.4 11.2 GO:0005922 connexon complex(GO:0005922)
0.3 44.4 GO:0031526 brush border membrane(GO:0031526)
0.3 92.6 GO:0072562 blood microparticle(GO:0072562)
0.2 38.2 GO:0030175 filopodium(GO:0030175)
0.2 2.2 GO:0045275 respiratory chain complex III(GO:0045275)
0.2 2.3 GO:0032584 growth cone membrane(GO:0032584)
0.1 3.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 4.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 1.0 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 27.9 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 1.3 GO:0042788 polysomal ribosome(GO:0042788)
0.1 4.6 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 4.2 GO:0030673 axolemma(GO:0030673)
0.1 0.7 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 10.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.3 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 4.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.8 GO:0043034 costamere(GO:0043034)
0.0 33.1 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 31.8 GO:0005615 extracellular space(GO:0005615)
0.0 7.9 GO:0000323 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 3.0 GO:0045211 postsynaptic membrane(GO:0045211)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
11.8 47.3 GO:0019862 IgA binding(GO:0019862)
6.5 32.5 GO:0055056 dehydroascorbic acid transporter activity(GO:0033300) D-glucose transmembrane transporter activity(GO:0055056)
5.7 17.1 GO:0034632 retinol transporter activity(GO:0034632)
4.8 38.2 GO:0001849 complement component C1q binding(GO:0001849)
3.9 27.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
2.8 57.0 GO:0001848 complement binding(GO:0001848)
2.5 10.0 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
1.7 22.7 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
1.6 7.9 GO:0004531 deoxyribonuclease II activity(GO:0004531)
1.5 8.7 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
1.1 12.0 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.8 22.7 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.7 82.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.6 11.2 GO:0005243 gap junction channel activity(GO:0005243)
0.5 14.9 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.5 6.9 GO:0004887 thyroid hormone receptor activity(GO:0004887) thyroid hormone binding(GO:0070324)
0.4 2.6 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.4 5.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.3 4.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.3 1.8 GO:0008142 oxysterol binding(GO:0008142)
0.3 2.3 GO:0005042 netrin receptor activity(GO:0005042)
0.3 2.2 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.3 1.8 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.2 7.1 GO:0043274 phospholipase binding(GO:0043274)
0.2 3.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 1.4 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.2 2.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.2 1.0 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 1.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 30.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 4.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 4.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 5.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 11.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 10.9 GO:0046332 SMAD binding(GO:0046332)
0.1 0.3 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 7.7 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.1 0.8 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1 1.0 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.3 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.8 GO:0015271 outward rectifier potassium channel activity(GO:0015271) potassium ion leak channel activity(GO:0022841)
0.0 0.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.9 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 2.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 4.1 GO:0019905 syntaxin binding(GO:0019905)
0.0 3.1 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 4.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 2.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.6 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 1.6 GO:0004540 ribonuclease activity(GO:0004540)
0.0 5.2 GO:0042623 ATPase activity, coupled(GO:0042623)
0.0 4.7 GO:0016746 transferase activity, transferring acyl groups(GO:0016746)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 17.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.7 53.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.6 169.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.5 38.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.3 19.9 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 4.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 6.0 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 6.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 8.3 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 2.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 3.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.9 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.8 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.7 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.2 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 38.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
1.9 32.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
1.8 41.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
1.3 30.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.7 99.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.5 11.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.4 8.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3 10.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.3 10.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.3 4.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.3 7.1 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.2 6.0 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2 4.7 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.2 10.0 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.2 1.8 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.2 9.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 4.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.2 17.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 2.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 8.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 14.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 2.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 0.8 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits