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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Otx1

Z-value: 0.88

Motif logo

Transcription factors associated with Otx1

Gene Symbol Gene ID Gene Info
ENSMUSG00000005917.16 Otx1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Otx1mm39_v1_chr11_-_21951605_219516310.142.5e-01Click!

Activity profile of Otx1 motif

Sorted Z-values of Otx1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Otx1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr18_-_68562385 5.80 ENSMUST00000052347.8
melanocortin 2 receptor
chr8_+_55024446 4.99 ENSMUST00000239166.2
ENSMUST00000239106.2
ENSMUST00000239152.2
ankyrin repeat and SOCs box-containing 5
chr11_+_98277276 4.38 ENSMUST00000041301.8
phenylethanolamine-N-methyltransferase
chr2_+_158344532 3.87 ENSMUST00000059889.4
adipogenin
chr2_+_91376650 3.41 ENSMUST00000099716.11
ENSMUST00000046769.16
ENSMUST00000111337.3
cytoskeleton associated protein 5
chr9_+_108356935 3.40 ENSMUST00000194147.2
ENSMUST00000065014.10
ENSMUST00000195483.6
ENSMUST00000195058.2
laminin, beta 2
chr13_-_61084358 3.19 ENSMUST00000225859.2
ENSMUST00000225167.2
ENSMUST00000021880.10
predicted gene, 49391
cytotoxic T lymphocyte-associated protein 2 alpha
chr19_-_10847121 3.13 ENSMUST00000120524.2
ENSMUST00000025645.14
transmembrane protein 132A
chr2_+_158344553 3.09 ENSMUST00000109484.2
adipogenin
chr5_+_146392371 2.91 ENSMUST00000238592.2
WASP family, member 3
chr4_-_11965691 2.71 ENSMUST00000108301.8
ENSMUST00000095144.10
ENSMUST00000108302.8
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr6_+_58810674 2.69 ENSMUST00000041401.11
hect domain and RLD 3
chr2_+_85715984 2.64 ENSMUST00000213441.3
olfactory receptor 1023
chr5_-_104261556 2.29 ENSMUST00000031249.8
SPARC-like 1
chr5_-_104261285 2.06 ENSMUST00000199947.2
SPARC-like 1
chr5_-_69748126 2.03 ENSMUST00000166298.8
glucosamine-6-phosphate deaminase 2
chr16_-_48592372 2.02 ENSMUST00000231701.3
T cell receptor associated transmembrane adaptor 1
chr7_-_37970734 1.96 ENSMUST00000032585.8
processing of precursor 4, ribonuclease P/MRP family, (S. cerevisiae)
chr5_+_146321757 1.90 ENSMUST00000016143.9
WASP family, member 3
chr2_+_169475436 1.89 ENSMUST00000109157.2
teashirt zinc finger family member 2
chr4_-_138546564 1.89 ENSMUST00000102512.11
phospholipase A2, group V
chrX_+_36390430 1.88 ENSMUST00000016553.5
NFKB activating protein
chr5_+_25427860 1.85 ENSMUST00000045737.14
polypeptide N-acetylgalactosaminyltransferase 11
chr2_-_153067297 1.80 ENSMUST00000099194.4
TSPY-like 3
chr9_-_20432562 1.79 ENSMUST00000215908.2
ENSMUST00000068296.8
ENSMUST00000174462.8
ENSMUST00000213418.2
zinc finger protein 266
chr10_-_7423341 1.73 ENSMUST00000169796.4
ENSMUST00000218087.2
UL16 binding protein 1
chr10_+_3923086 1.67 ENSMUST00000117291.8
ENSMUST00000120585.8
ENSMUST00000043735.8
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr1_-_165535617 1.65 ENSMUST00000040357.11
RCSD domain containing 1
chr19_+_5074070 1.63 ENSMUST00000025826.7
ENSMUST00000237371.2
ENSMUST00000235416.2
solute carrier family 29 (nucleoside transporters), member 2
chr16_-_48592319 1.59 ENSMUST00000239408.2
T cell receptor associated transmembrane adaptor 1
chr17_-_21110913 1.59 ENSMUST00000061278.2
vomeronasal 1 receptor 231
chr13_+_93908138 1.56 ENSMUST00000091403.6
arylsulfatase B
chr5_-_65117375 1.53 ENSMUST00000062315.7
ENSMUST00000239485.2
ENSMUST00000201307.3
toll-like receptor 6
chr5_-_115622356 1.52 ENSMUST00000112067.8
sirtuin 4
chr16_-_59452883 1.47 ENSMUST00000118438.8
ADP-ribosylation factor-like 6
chr5_+_110071266 1.43 ENSMUST00000112544.8
predicted gene 15446
chr18_+_24087725 1.39 ENSMUST00000225682.2
ENSMUST00000060762.6
zinc finger protein 397
chr3_+_18108313 1.36 ENSMUST00000026120.8
basic helix-loop-helix family, member e22
chr2_-_73283010 1.32 ENSMUST00000151939.2
WAS/WASL interacting protein family, member 1
chr12_-_114012399 1.31 ENSMUST00000103468.3
immunoglobulin heavy variable V11-2
chr16_+_22926504 1.27 ENSMUST00000187168.7
ENSMUST00000232287.2
ENSMUST00000077605.12
eukaryotic translation initiation factor 4A2
chr7_-_7250327 1.25 ENSMUST00000170922.2
vomeronasal 2, receptor 29
chr7_-_29772226 1.18 ENSMUST00000183115.8
ENSMUST00000182919.8
ENSMUST00000183190.2
ENSMUST00000080834.15
zinc finger protein 82
chr12_+_103400470 1.17 ENSMUST00000079294.12
ENSMUST00000076788.12
ENSMUST00000076702.12
ENSMUST00000066701.13
ENSMUST00000085065.12
ENSMUST00000140838.2
interferon, alpha-inducible protein 27
chr16_+_49620883 1.15 ENSMUST00000229640.2
CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
chr8_-_94825556 1.14 ENSMUST00000034206.6
Bardet-Biedl syndrome 2 (human)
chr13_-_23553139 1.13 ENSMUST00000152557.8
zinc finger protein 322A
chrX_+_106132840 1.13 ENSMUST00000118666.8
ENSMUST00000053375.4
purinergic receptor P2Y, G-protein coupled 10
chr19_-_42768374 1.13 ENSMUST00000069298.13
ENSMUST00000160455.8
ENSMUST00000162004.8
HPS1, biogenesis of lysosomal organelles complex 3 subunit 1
chr11_+_94827050 1.12 ENSMUST00000001547.8
collagen, type I, alpha 1
chr13_-_61045252 1.11 ENSMUST00000021884.10
cytotoxic T lymphocyte-associated protein 2 beta
chr4_-_137512682 1.10 ENSMUST00000133473.2
alkaline phosphatase, liver/bone/kidney
chr6_-_148732893 1.08 ENSMUST00000145960.2
importin 8
chr7_-_4066154 1.07 ENSMUST00000086401.10
ENSMUST00000068865.13
leukocyte-associated Ig-like receptor 1
chr7_-_4066125 1.06 ENSMUST00000108600.9
ENSMUST00000205296.2
leukocyte-associated Ig-like receptor 1
chr7_-_4066194 1.05 ENSMUST00000086400.13
leukocyte-associated Ig-like receptor 1
chr2_-_12306722 1.02 ENSMUST00000028106.11
integrin alpha 8
chr12_-_65120674 1.00 ENSMUST00000220983.2
ENSMUST00000220730.2
ENSMUST00000021332.10
FK506 binding protein 3
chr17_+_24768808 1.00 ENSMUST00000228550.2
ENSMUST00000035565.5
polycystin 1, transient receptor poteintial channel interacting
chr2_-_156022054 0.99 ENSMUST00000126992.8
ENSMUST00000146288.8
ENSMUST00000029149.13
ENSMUST00000109587.9
ENSMUST00000109584.8
RNA binding motif protein 39
chr11_+_78237492 0.98 ENSMUST00000100755.4
unc-119 lipid binding chaperone
chr1_-_118239146 0.96 ENSMUST00000027623.9
translin
chr5_-_5799315 0.96 ENSMUST00000015796.9
six transmembrane epithelial antigen of the prostate 1
chr18_+_57601541 0.95 ENSMUST00000091892.4
ENSMUST00000209782.2
cortexin 3
chr1_-_85664246 0.94 ENSMUST00000064788.14
RIKEN cDNA A630001G21 gene
chr15_+_80017315 0.93 ENSMUST00000023050.9
TGF-beta activated kinase 1/MAP3K7 binding protein 1
chr3_+_66892979 0.92 ENSMUST00000162362.8
ENSMUST00000065074.14
ENSMUST00000065047.13
arginine/serine-rich coiled-coil 1
chr2_+_112096154 0.89 ENSMUST00000110991.9
solute carrier family 12, member 6
chr5_+_53713137 0.89 ENSMUST00000087360.9
recombination signal binding protein for immunoglobulin kappa J region
chr7_+_27537982 0.88 ENSMUST00000205701.2
zinc finger protein 59
chr3_+_66893031 0.87 ENSMUST00000046542.13
ENSMUST00000162693.8
arginine/serine-rich coiled-coil 1
chr10_+_11025150 0.87 ENSMUST00000044053.13
SNF2 histone linker PHD RING helicase
chr16_-_19341016 0.86 ENSMUST00000214315.2
olfactory receptor 167
chr3_+_95018324 0.85 ENSMUST00000009102.9
vacuolar protein sorting 72
chr6_+_108771840 0.84 ENSMUST00000204483.2
ADP-ribosylation factor-like 8B
chr17_+_33483650 0.84 ENSMUST00000217023.3
olfactory receptor 63
chr13_-_61045212 0.84 ENSMUST00000171347.9
cytotoxic T lymphocyte-associated protein 2 beta
chr4_-_126094910 0.82 ENSMUST00000136157.8
thyroid hormone receptor associated protein 3
chr4_+_74160705 0.79 ENSMUST00000077851.10
lysine (K)-specific demethylase 4C
chr9_-_62895197 0.78 ENSMUST00000216209.2
protein inhibitor of activated STAT 1
chr12_-_98225676 0.76 ENSMUST00000021390.9
galactosylceramidase
chr17_+_21031817 0.75 ENSMUST00000232810.2
ENSMUST00000233712.2
ENSMUST00000232852.2
vomeronasal 1 receptor 229
chrM_+_10167 0.74 ENSMUST00000082414.1
mitochondrially encoded NADH dehydrogenase 4
chr6_+_48531710 0.74 ENSMUST00000114545.8
ENSMUST00000153222.2
ENSMUST00000204071.2
ENSMUST00000101436.3
ENSMUST00000203627.2
leucine rich repeat containing 61
chr15_-_57128522 0.72 ENSMUST00000137764.2
ENSMUST00000022995.13
solute carrier family 22 (organic cation transporter), member 22
chr9_+_117888124 0.71 ENSMUST00000123690.2
5-azacytidine induced gene 2
chr2_+_112114906 0.71 ENSMUST00000053666.8
solute carrier family 12, member 6
chr7_-_85985625 0.69 ENSMUST00000069279.5
olfactory receptor 307
chr9_+_108367801 0.69 ENSMUST00000006854.13
ubiquitin specific peptidase 19
chr6_-_89847511 0.68 ENSMUST00000089418.5
vomeronasal 1 receptor 43
chr11_+_3913970 0.67 ENSMUST00000109985.8
ENSMUST00000020705.5
pescadillo ribosomal biogenesis factor 1
chr19_-_7017295 0.66 ENSMUST00000025918.9
stress-induced phosphoprotein 1
chr13_+_18901459 0.65 ENSMUST00000072961.6
VPS41 HOPS complex subunit
chr17_+_47922497 0.64 ENSMUST00000024778.3
mediator complex subunit 20
chr8_-_55171699 0.63 ENSMUST00000144711.9
WD repeat domain 17
chr13_-_63579497 0.61 ENSMUST00000160931.2
ENSMUST00000099444.10
ENSMUST00000220684.2
ENSMUST00000161977.8
ENSMUST00000163091.8
Fanconi anemia, complementation group C
chr11_-_120344299 0.60 ENSMUST00000026452.3
phosphodiesterase 6G, cGMP-specific, rod, gamma
chr17_+_36172210 0.56 ENSMUST00000074259.15
ENSMUST00000174873.2
nurim (nuclear envelope membrane protein)
chr19_-_5738936 0.56 ENSMUST00000113615.9
pecanex homolog 3
chr16_-_63684477 0.55 ENSMUST00000232654.2
ENSMUST00000064405.8
Eph receptor A3
chr13_-_21934675 0.54 ENSMUST00000102983.2
H4 clustered histone 12
chr12_-_52074846 0.53 ENSMUST00000040161.5
G protein-coupled receptor 33
chr16_+_91444730 0.53 ENSMUST00000119368.8
ENSMUST00000114037.9
ENSMUST00000114036.9
ENSMUST00000122302.8
Son DNA binding protein
chr8_-_96615138 0.53 ENSMUST00000034097.8
glutamatic-oxaloacetic transaminase 2, mitochondrial
chr6_+_70332836 0.52 ENSMUST00000103390.3
immunoglobulin kappa variable 8-18
chr9_+_108911547 0.52 ENSMUST00000026735.9
coiled-coil domain containing 51
chr11_+_115455260 0.51 ENSMUST00000021085.11
nucleoporin 85
chr6_+_68657317 0.50 ENSMUST00000198735.2
immunoglobulin kappa variable 10-95
chr6_-_133032779 0.49 ENSMUST00000095391.3
taste receptor, type 2, member 140
chr7_+_16186704 0.49 ENSMUST00000019302.10
transmembrane protein 160
chr6_-_58412879 0.49 ENSMUST00000078890.5
vomeronasal 1 receptor 30
chr1_+_131838220 0.47 ENSMUST00000189946.7
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr6_-_29507944 0.47 ENSMUST00000101614.10
ENSMUST00000078112.13
kielin/chordin-like protein
chr15_+_78819119 0.46 ENSMUST00000138880.9
ENSMUST00000041164.4
nucleolar protein 12
chr1_+_118249558 0.42 ENSMUST00000027626.13
ENSMUST00000112688.10
nucleolar protein interacting with the FHA domain of MKI67
chr12_-_46865709 0.40 ENSMUST00000021438.8
NOVA alternative splicing regulator 1
chr9_+_106330437 0.40 ENSMUST00000185874.7
poly(rC) binding protein 4
chr7_-_100311522 0.40 ENSMUST00000151123.8
ENSMUST00000208812.2
ENSMUST00000107047.10
pleckstrin homology domain containing, family B (evectins) member 1
chr6_+_132928065 0.40 ENSMUST00000070991.5
taste receptor, type 2, member 129
chr14_+_52122439 0.39 ENSMUST00000167984.2
methyltransferase like 17
chr12_-_26506422 0.39 ENSMUST00000020970.10
radical S-adenosyl methionine domain containing 2
chr10_-_111829393 0.38 ENSMUST00000161870.3
GLI pathogenesis-related 1 (glioma)
chr10_+_123099945 0.37 ENSMUST00000238972.2
ENSMUST00000050756.8
TAFA chemokine like family member 2
chr12_-_13299197 0.34 ENSMUST00000071103.10
DEAD box helicase 1
chr8_-_65440298 0.33 ENSMUST00000095295.3
tripartite motif-containing 75
chr4_+_143515922 0.32 ENSMUST00000085144.11
ENSMUST00000149739.2
ENSMUST00000105770.2
PRAME like 25
chr19_-_41921676 0.32 ENSMUST00000075280.12
ENSMUST00000112123.4
exosome component 1
chr2_+_87576198 0.32 ENSMUST00000217572.2
olfactory receptor 1140
chrX_-_42256694 0.31 ENSMUST00000115058.8
ENSMUST00000115059.8
teneurin transmembrane protein 1
chr16_-_18885809 0.31 ENSMUST00000200211.2
immunoglobulin lambda joining 3
chr9_-_53521585 0.29 ENSMUST00000034547.6
acetyl-Coenzyme A acetyltransferase 1
chr12_-_103660946 0.28 ENSMUST00000118101.2
serine (or cysteine) peptidase inhibitor, clade A, member 1F
chr5_-_146158235 0.27 ENSMUST00000161859.8
ring finger protein (C3H2C3 type) 6
chr11_-_116165024 0.25 ENSMUST00000021133.16
signal recognition particle 68
chr11_+_103007054 0.23 ENSMUST00000053063.7
hexamethylene bis-acetamide inducible 1
chr6_+_57012898 0.23 ENSMUST00000078186.4
vomeronasal 1 receptor 8
chr7_-_100311621 0.23 ENSMUST00000079176.14
pleckstrin homology domain containing, family B (evectins) member 1
chr4_-_96552349 0.21 ENSMUST00000030299.8
cytochrome P450, family 2, subfamily j, polypeptide 5
chr4_-_130116119 0.21 ENSMUST00000023884.7
leucine decarboxylase 1
chr17_+_28075415 0.20 ENSMUST00000114849.3
UHRF1 (ICBP90) binding protein 1
chr9_+_68561042 0.20 ENSMUST00000034766.14
RAR-related orphan receptor alpha
chr9_-_38577138 0.20 ENSMUST00000076542.2
olfactory receptor 917
chr13_+_36142822 0.20 ENSMUST00000225537.2
protein phosphatase 1, regulatory subunit 3G
chr9_-_109105194 0.18 ENSMUST00000198048.5
F-box and WD-40 domain protein 14
chr17_+_36172235 0.17 ENSMUST00000172931.2
nurim (nuclear envelope membrane protein)
chr2_-_37312881 0.17 ENSMUST00000112936.4
ENSMUST00000112934.8
ring finger and CCCH-type zinc finger domains 2
chr8_-_65440483 0.16 ENSMUST00000210982.2
tripartite motif-containing 75
chr12_-_103660916 0.16 ENSMUST00000117053.8
serine (or cysteine) peptidase inhibitor, clade A, member 1F
chr3_-_148696155 0.16 ENSMUST00000196526.5
ENSMUST00000200543.5
ENSMUST00000200154.5
adhesion G protein-coupled receptor L2
chr2_+_111145783 0.14 ENSMUST00000082167.5
olfactory receptor 1280
chr15_+_102391614 0.12 ENSMUST00000229432.2
poly(rC) binding protein 2
chr7_+_103652466 0.11 ENSMUST00000209757.3
olfactory receptor 638
chr1_+_186947683 0.11 ENSMUST00000065573.14
ENSMUST00000110943.9
ENSMUST00000044812.12
G patch domain containing 2
chr11_-_116164928 0.10 ENSMUST00000106425.4
signal recognition particle 68
chr7_+_86444235 0.09 ENSMUST00000233099.2
ENSMUST00000164996.2
vomeronasal 2, receptor 77
chr10_+_78848306 0.09 ENSMUST00000216030.2
olfactory receptor 1351
chr1_+_131838294 0.08 ENSMUST00000062264.8
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr8_+_85676489 0.08 ENSMUST00000121880.8
retbindin
chr10_-_39009844 0.07 ENSMUST00000134279.8
ENSMUST00000139743.8
ENSMUST00000149949.8
ENSMUST00000124941.8
ENSMUST00000125042.8
ENSMUST00000063204.9
family with sequence similarity 229, member B
chr2_-_89273344 0.07 ENSMUST00000216123.2
olfactory receptor 1240
chr11_-_69127848 0.06 ENSMUST00000021259.9
ENSMUST00000108665.8
ENSMUST00000108664.2
guanylate cyclase 2e
chr16_+_88966321 0.06 ENSMUST00000089098.2
predicted gene 7735
chr13_+_21363602 0.04 ENSMUST00000222544.2
tripartite motif-containing 27
chr6_-_68609426 0.04 ENSMUST00000103328.3
immunoglobulin kappa variable 10-96
chr13_-_58422647 0.03 ENSMUST00000225034.2
G kinase anchoring protein 1
chr12_+_70499869 0.03 ENSMUST00000021471.13
thioredoxin-related transmembrane protein 1
chr19_-_6107766 0.02 ENSMUST00000235520.2
ENSMUST00000007482.8
mitochondrial ribosomal protein L49
chr18_+_86729645 0.01 ENSMUST00000122464.8
cerebellin 2 precursor protein
chr9_+_19351562 0.00 ENSMUST00000217273.2
olfactory receptor 849
chr10_+_127478844 0.00 ENSMUST00000092074.12
ENSMUST00000120279.2
signal transducer and activator of transcription 6
chr1_+_37258272 0.00 ENSMUST00000027288.10
cyclic nucleotide gated channel alpha 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0072248 metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.9 4.4 GO:0042414 epinephrine metabolic process(GO:0042414)
0.6 3.6 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.6 3.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.4 1.7 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.4 1.6 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.4 1.5 GO:0070340 negative regulation of toll-like receptor 2 signaling pathway(GO:0034136) TRIF-dependent toll-like receptor signaling pathway(GO:0035666) detection of bacterial lipopeptide(GO:0070340)
0.3 1.7 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.3 1.0 GO:0060854 patterning of lymph vessels(GO:0060854)
0.3 1.9 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.3 1.5 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.3 1.5 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.3 1.1 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.2 1.0 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.2 1.9 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.2 1.0 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.2 0.5 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.2 0.9 GO:1901297 positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.2 2.0 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.2 0.5 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.2 2.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 1.6 GO:0071474 cellular hyperosmotic response(GO:0071474)
0.2 1.1 GO:1903232 melanosome assembly(GO:1903232)
0.1 4.7 GO:0050872 white fat cell differentiation(GO:0050872)
0.1 0.7 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
0.1 0.7 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 1.1 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.6 GO:0019046 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.1 1.4 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.1 0.6 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 1.1 GO:0008228 opsonization(GO:0008228)
0.1 2.0 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 3.2 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.1 0.4 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.1 0.3 GO:0006550 isoleucine catabolic process(GO:0006550)
0.1 1.0 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 4.8 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 0.4 GO:1902163 negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902163)
0.1 0.5 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.2 GO:2000863 positive regulation of estrogen secretion(GO:2000863)
0.1 1.6 GO:0015858 nucleoside transport(GO:0015858)
0.1 0.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.8 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 0.8 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 0.8 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 5.8 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)
0.1 0.7 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) nucleolus organization(GO:0007000)
0.0 2.5 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 1.9 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 2.9 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.3 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.7 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.0 1.1 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.8 GO:0043486 histone exchange(GO:0043486)
0.0 1.0 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 3.7 GO:0019236 response to pheromone(GO:0019236)
0.0 1.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 1.6 GO:0009268 response to pH(GO:0009268)
0.0 0.6 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.6 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.9 GO:0006334 nucleosome assembly(GO:0006334)
0.0 1.0 GO:0061077 chaperone-mediated protein folding(GO:0061077)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.4 GO:0005608 laminin-3 complex(GO:0005608)
0.4 1.1 GO:0005584 collagen type I trimer(GO:0005584)
0.3 2.0 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 4.4 GO:0043196 varicosity(GO:0043196)
0.1 3.6 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.9 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 3.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 1.1 GO:0034464 BBSome(GO:0034464)
0.1 0.3 GO:0071920 cleavage body(GO:0071920)
0.1 0.6 GO:0033263 CORVET complex(GO:0033263)
0.1 1.0 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.7 GO:0070545 PeBoW complex(GO:0070545)
0.1 7.3 GO:0005811 lipid particle(GO:0005811)
0.0 1.1 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 1.1 GO:0031082 BLOC complex(GO:0031082)
0.0 0.4 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 1.8 GO:0051233 spindle midzone(GO:0051233)
0.0 0.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 1.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 1.5 GO:0016592 mediator complex(GO:0016592)
0.0 0.9 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 1.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.8 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 4.8 GO:0030027 lamellipodium(GO:0030027)
0.0 1.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 5.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 4.8 GO:0016607 nuclear speck(GO:0016607)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.8 GO:0004977 melanocortin receptor activity(GO:0004977)
0.7 2.7 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.7 2.0 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.7 2.0 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.4 1.7 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.4 1.6 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.4 1.5 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.2 1.9 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 1.6 GO:0004065 arylsulfatase activity(GO:0004065)
0.2 0.5 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.2 1.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 3.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.5 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 1.0 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.8 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 1.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 1.7 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 1.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.5 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.3 GO:0033677 DNA/RNA helicase activity(GO:0033677)
0.1 1.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.5 GO:0004875 complement receptor activity(GO:0004875)
0.1 0.4 GO:0005047 signal recognition particle binding(GO:0005047) endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 1.1 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.7 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.1 0.5 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 1.6 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 0.7 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.5 GO:0050733 RS domain binding(GO:0050733)
0.1 4.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.9 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 1.0 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.9 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.3 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.0 1.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:2001069 glycogen binding(GO:2001069)
0.0 0.8 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 4.4 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.8 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 3.7 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.6 GO:0030553 cGMP binding(GO:0030553)
0.0 1.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.8 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 1.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 2.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 2.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 2.4 GO:0005178 integrin binding(GO:0005178)
0.0 0.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 3.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 3.4 PID AURORA A PATHWAY Aurora A signaling
0.1 0.8 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 1.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.0 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 2.5 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 3.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.9 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.6 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.5 PID EPHA FWDPATHWAY EPHA forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2 4.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.2 1.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.9 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 3.6 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 0.9 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 1.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.9 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.8 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 3.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 3.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 5.8 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.6 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 5.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.5 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 1.5 REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides