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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Ovol1

Z-value: 0.31

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Transcription factors associated with Ovol1

Gene Symbol Gene ID Gene Info
Ovol1
ENSMUSG00000024922.3 Ovol1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Ovol1mm39_v1_chr19_-_5610628_5610674-0.603.2e-08Click!

Activity profile of Ovol1 motif

Sorted Z-values of Ovol1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Ovol1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_+_21215472 3.84 ENSMUST00000081542.6
Kcnd2
potassium voltage-gated channel, Shal-related family, member 2
chr11_-_42070517 2.78 ENSMUST00000206105.2
ENSMUST00000153147.3
Gabra1
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr18_+_37153149 1.73 ENSMUST00000047614.4
Pcdha12
protocadherin alpha 12
chr18_+_37822865 1.49 ENSMUST00000195112.2
Pcdhgb2
protocadherin gamma subfamily B, 2
chr7_+_18810167 1.35 ENSMUST00000108479.2
Dmwd
dystrophia myotonica-containing WD repeat motif
chr2_-_79959178 1.35 ENSMUST00000102654.11
ENSMUST00000102655.10
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chrX_-_23151771 0.80 ENSMUST00000115319.9
Klhl13
kelch-like 13
chr5_+_65505657 0.77 ENSMUST00000031096.11
Klb
klotho beta
chr14_-_34032311 0.74 ENSMUST00000111917.3
ENSMUST00000228704.2
Shld2
shieldin complex subunit 2
chr11_-_32217547 0.60 ENSMUST00000109389.9
ENSMUST00000129010.2
ENSMUST00000020530.12
Nprl3
nitrogen permease regulator-like 3
chr17_+_72076728 0.59 ENSMUST00000230305.2
Clip4
CAP-GLY domain containing linker protein family, member 4
chr14_-_34032450 0.58 ENSMUST00000227375.2
Shld2
shieldin complex subunit 2
chr17_+_72076678 0.57 ENSMUST00000230427.2
ENSMUST00000229952.2
ENSMUST00000230333.2
Clip4
CAP-GLY domain containing linker protein family, member 4
chr14_-_75829389 0.47 ENSMUST00000165569.3
ENSMUST00000035243.5
Cby2
chibby family member 2
chr8_-_106052884 0.44 ENSMUST00000210412.2
ENSMUST00000210801.2
ENSMUST00000070508.8
Lrrc29
leucine rich repeat containing 29
chr2_-_44912927 0.30 ENSMUST00000202432.4
Zeb2
zinc finger E-box binding homeobox 2
chr2_+_172090412 0.22 ENSMUST00000038532.2
Mc3r
melanocortin 3 receptor
chr2_-_89156522 0.20 ENSMUST00000099785.2
Olfr1232
olfactory receptor 1232
chr10_+_73782857 0.11 ENSMUST00000191709.6
ENSMUST00000193739.6
ENSMUST00000195531.6
Pcdh15
protocadherin 15
chr8_+_106052970 0.05 ENSMUST00000015000.12
ENSMUST00000098453.9
Tmem208
transmembrane protein 208
chr19_+_12186932 0.05 ENSMUST00000072316.5
Olfr1431
olfactory receptor 1431
chr2_-_111100733 0.04 ENSMUST00000099619.6
Olfr1277
olfactory receptor 1277
chr14_-_51493569 0.02 ENSMUST00000061936.8
Rnase2a
ribonuclease, RNase A family, 2A (liver, eosinophil-derived neurotoxin)
chr2_-_111104451 0.01 ENSMUST00000214760.2
Olfr1277
olfactory receptor 1277

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 GO:0071420 cellular response to histamine(GO:0071420)
0.1 4.1 GO:0045475 locomotor rhythm(GO:0045475)
0.1 0.8 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1 1.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.3 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.1 GO:0050973 detection of mechanical stimulus involved in equilibrioception(GO:0050973)
0.0 0.6 GO:2000785 TORC1 signaling(GO:0038202) regulation of autophagosome assembly(GO:2000785)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:1990130 Iml1 complex(GO:1990130)
0.1 3.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 2.8 GO:1902711 GABA-A receptor complex(GO:1902711)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.8 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.3 2.8 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 1.3 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.2 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.8 GO:0017134 fibroblast growth factor binding(GO:0017134)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 3.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.8 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation