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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Pax3

Z-value: 0.80

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Transcription factors associated with Pax3

Gene Symbol Gene ID Gene Info
Pax3
ENSMUSG00000004872.16 Pax3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pax3mm39_v1_chr1_-_78173468_781734820.309.6e-03Click!

Activity profile of Pax3 motif

Sorted Z-values of Pax3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Pax3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr10_-_70428611 9.39 ENSMUST00000162251.8
Phyhipl
phytanoyl-CoA hydroxylase interacting protein-like
chr19_-_36714053 7.09 ENSMUST00000087321.4
Ppp1r3c
protein phosphatase 1, regulatory subunit 3C
chr5_-_87240405 6.88 ENSMUST00000132667.2
ENSMUST00000145617.8
ENSMUST00000094649.11
Ugt2b36
UDP glucuronosyltransferase 2 family, polypeptide B36
chr13_+_4484305 6.58 ENSMUST00000021630.15
Akr1c6
aldo-keto reductase family 1, member C6
chr18_+_37100672 6.32 ENSMUST00000193777.6
ENSMUST00000193389.2
Pcdha6
protocadherin alpha 6
chr2_+_102489558 5.69 ENSMUST00000111213.8
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr14_+_52131067 5.63 ENSMUST00000047726.12
Slc39a2
solute carrier family 39 (zinc transporter), member 2
chr3_-_116047148 4.81 ENSMUST00000090473.7
Gpr88
G-protein coupled receptor 88
chr2_-_136229849 4.74 ENSMUST00000035264.9
ENSMUST00000077200.4
Pak5
p21 (RAC1) activated kinase 5
chr12_+_52746158 4.58 ENSMUST00000095737.5
Akap6
A kinase (PRKA) anchor protein 6
chr3_-_59170245 4.32 ENSMUST00000050360.14
ENSMUST00000199609.2
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr16_+_4964849 4.06 ENSMUST00000165810.2
ENSMUST00000230616.2
Sec14l5
SEC14-like lipid binding 5
chr3_-_33136153 4.02 ENSMUST00000108225.10
Pex5l
peroxisomal biogenesis factor 5-like
chrX_+_113384008 3.73 ENSMUST00000113371.8
ENSMUST00000040504.12
Klhl4
kelch-like 4
chr12_+_38831093 3.71 ENSMUST00000161513.9
Etv1
ets variant 1
chr12_+_38830283 3.36 ENSMUST00000162563.8
ENSMUST00000161164.8
ENSMUST00000160996.8
Etv1
ets variant 1
chr12_+_38830812 3.19 ENSMUST00000160856.8
Etv1
ets variant 1
chr11_-_88742285 2.67 ENSMUST00000107903.8
Akap1
A kinase (PRKA) anchor protein 1
chr17_-_23990512 2.66 ENSMUST00000226460.2
Flywch1
FLYWCH-type zinc finger 1
chr7_-_99994257 2.53 ENSMUST00000207634.2
Ppme1
protein phosphatase methylesterase 1
chr17_-_23990479 2.40 ENSMUST00000086325.13
Flywch1
FLYWCH-type zinc finger 1
chr15_-_99322415 2.32 ENSMUST00000161004.2
Nckap5l
NCK-associated protein 5-like
chr12_-_75596441 2.16 ENSMUST00000218716.2
Ppp2r5e
protein phosphatase 2, regulatory subunit B', epsilon
chr10_-_80374916 1.99 ENSMUST00000219648.2
Atp8b3
ATPase, class I, type 8B, member 3
chrX_+_156485570 1.94 ENSMUST00000112520.2
Smpx
small muscle protein, X-linked
chr3_+_108093645 1.83 ENSMUST00000050909.7
ENSMUST00000106659.3
ENSMUST00000106656.2
Amigo1
adhesion molecule with Ig like domain 1
chr13_+_14804739 1.65 ENSMUST00000178289.3
ENSMUST00000038690.6
ENSMUST00000222052.2
AW209491
expressed sequence AW209491
chr14_-_31503869 1.64 ENSMUST00000227089.2
Ankrd28
ankyrin repeat domain 28
chrX_+_48559327 1.62 ENSMUST00000114904.10
Arhgap36
Rho GTPase activating protein 36
chr18_+_35695199 1.62 ENSMUST00000236860.2
ENSMUST00000166793.10
ENSMUST00000237780.2
ENSMUST00000236507.2
ENSMUST00000235960.2
ENSMUST00000237061.2
Matr3
matrin 3
chr10_+_36382810 1.53 ENSMUST00000167191.8
ENSMUST00000058738.11
Hs3st5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr4_+_126971167 1.49 ENSMUST00000046751.13
ENSMUST00000094713.4
Zmym6
zinc finger, MYM-type 6
chr7_+_29821340 1.43 ENSMUST00000098596.11
ENSMUST00000153792.2
Zfp382
zinc finger protein 382
chr5_-_112400375 1.32 ENSMUST00000112385.8
Cryba4
crystallin, beta A4
chr8_+_66070661 1.24 ENSMUST00000110258.8
ENSMUST00000110256.8
ENSMUST00000110255.8
Marchf1
membrane associated ring-CH-type finger 1
chr19_+_12647803 1.20 ENSMUST00000207341.3
ENSMUST00000208494.3
ENSMUST00000208657.3
Olfr1442
olfactory receptor 1442
chr1_-_130815144 0.97 ENSMUST00000121040.8
Il24
interleukin 24
chr18_+_34892599 0.88 ENSMUST00000097622.4
Fam53c
family with sequence similarity 53, member C
chr1_+_176642226 0.87 ENSMUST00000056773.15
ENSMUST00000027785.15
Sdccag8
serologically defined colon cancer antigen 8
chr13_-_74538899 0.82 ENSMUST00000223163.3
Zfp72
zinc finger protein 72
chr19_-_46136765 0.72 ENSMUST00000026259.16
Pitx3
paired-like homeodomain transcription factor 3
chr4_+_109092459 0.62 ENSMUST00000106631.9
Calr4
calreticulin 4
chr8_+_111345209 0.59 ENSMUST00000034190.11
Vac14
Vac14 homolog (S. cerevisiae)
chr9_-_114469121 0.59 ENSMUST00000070117.8
Cnot10
CCR4-NOT transcription complex, subunit 10
chr7_-_133384449 0.53 ENSMUST00000063669.8
Dhx32
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr16_+_20367327 0.47 ENSMUST00000003319.6
ENSMUST00000232680.2
ENSMUST00000232490.2
Abcf3
ATP-binding cassette, sub-family F (GCN20), member 3
chr5_+_136937083 0.33 ENSMUST00000008131.10
Ift22
intraflagellar transport 22
chr14_-_43964942 0.23 ENSMUST00000165553.2
Gm16506
predicted gene 16506
chr2_+_168072519 0.16 ENSMUST00000099071.5
Mocs3
molybdenum cofactor synthesis 3
chr4_+_115099237 0.14 ENSMUST00000118278.2
Cyp4a29
cytochrome P450, family 4, subfamily a, polypeptide 29
chr11_+_58664014 0.10 ENSMUST00000203256.4
Olfr315
olfactory receptor 315
chr16_+_32698149 0.09 ENSMUST00000023489.11
ENSMUST00000171325.9
Fyttd1
forty-two-three domain containing 1
chr4_-_25281750 0.06 ENSMUST00000038705.8
ENSMUST00000102994.10
Ufl1
UFM1 specific ligase 1
chr6_+_43083303 0.02 ENSMUST00000213649.2
Olfr441
olfactory receptor 441

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.6 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
1.1 4.3 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.8 5.7 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.8 4.6 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.7 4.8 GO:0061743 motor learning(GO:0061743)
0.5 10.3 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.5 4.0 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.3 2.7 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.3 1.5 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2 0.7 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.1 5.6 GO:0006829 zinc II ion transport(GO:0006829)
0.1 7.1 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 2.0 GO:0045332 phospholipid translocation(GO:0045332)
0.1 0.8 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 1.8 GO:0007413 axonal fasciculation(GO:0007413)
0.1 2.5 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.2 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 2.3 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 1.0 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 1.6 GO:0003281 ventricular septum development(GO:0003281)
0.0 0.1 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.6 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.6 7.1 GO:0042587 glycogen granule(GO:0042587)
0.5 4.0 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.2 1.9 GO:0005927 muscle tendon junction(GO:0005927)
0.1 2.7 GO:0030061 mitochondrial crista(GO:0030061)
0.1 5.7 GO:0030673 axolemma(GO:0030673)
0.1 0.6 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 2.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 2.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 4.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 3.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.9 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.6 GO:0016363 nuclear matrix(GO:0016363)
0.0 2.0 GO:0001669 acrosomal vesicle(GO:0001669)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.6 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.9 5.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.7 4.0 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.4 4.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.3 1.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3 4.6 GO:0043495 protein anchor(GO:0043495)
0.2 2.7 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.2 6.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 5.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 11.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 2.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 4.8 GO:0003774 motor activity(GO:0003774)
0.0 11.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.8 GO:0015459 potassium channel regulator activity(GO:0015459)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 2.7 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.0 PID IL23 PATHWAY IL23-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.2 5.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 2.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 5.7 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 2.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 2.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.9 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes