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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Pax4

Z-value: 0.92

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Transcription factors associated with Pax4

Gene Symbol Gene ID Gene Info
Pax4
ENSMUSG00000029706.16 Pax4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pax4mm39_v1_chr6_-_28447179_28447179-0.161.9e-01Click!

Activity profile of Pax4 motif

Sorted Z-values of Pax4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Pax4

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr9_+_59564482 6.90 ENSMUST00000216620.2
ENSMUST00000217038.2
Pkm
pyruvate kinase, muscle
chr9_+_59563838 6.58 ENSMUST00000163694.4
Pkm
pyruvate kinase, muscle
chr1_-_79838897 6.49 ENSMUST00000190724.2
Serpine2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr9_+_59563872 5.99 ENSMUST00000215623.2
ENSMUST00000215660.2
ENSMUST00000217353.2
Pkm
pyruvate kinase, muscle
chr5_+_66833434 5.87 ENSMUST00000031131.11
Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr9_-_58066484 5.81 ENSMUST00000041477.15
Islr
immunoglobulin superfamily containing leucine-rich repeat
chr9_+_58395850 5.41 ENSMUST00000085658.5
Insyn1
inhibitory synaptic factor 1
chr17_+_35278011 4.90 ENSMUST00000007255.13
ENSMUST00000174493.8
Ddah2
dimethylarginine dimethylaminohydrolase 2
chr9_+_36743980 4.84 ENSMUST00000034630.15
Fez1
fasciculation and elongation protein zeta 1 (zygin I)
chr17_+_27160356 4.73 ENSMUST00000229490.2
ENSMUST00000201702.5
ENSMUST00000177932.7
ENSMUST00000201349.6
Syngap1
synaptic Ras GTPase activating protein 1 homolog (rat)
chr1_-_65071897 4.27 ENSMUST00000162800.8
ENSMUST00000069142.12
Akr1cl
aldo-keto reductase family 1, member C-like
chr16_+_22965286 4.23 ENSMUST00000023593.6
Adipoq
adiponectin, C1Q and collagen domain containing
chr16_+_22965330 3.95 ENSMUST00000171309.2
Adipoq
adiponectin, C1Q and collagen domain containing
chr12_-_90705212 3.88 ENSMUST00000082432.6
Dio2
deiodinase, iodothyronine, type II
chr17_+_17622934 3.87 ENSMUST00000115576.3
Lix1
limb and CNS expressed 1
chr7_+_58307930 3.66 ENSMUST00000168747.3
Atp10a
ATPase, class V, type 10A
chr17_+_27160203 3.56 ENSMUST00000194598.6
Syngap1
synaptic Ras GTPase activating protein 1 homolog (rat)
chr9_-_37058590 3.49 ENSMUST00000080754.12
ENSMUST00000188057.7
ENSMUST00000039674.13
Pknox2
Pbx/knotted 1 homeobox 2
chr13_-_110416637 3.48 ENSMUST00000167824.3
ENSMUST00000224180.2
Rab3c
RAB3C, member RAS oncogene family
chr18_-_43925932 3.19 ENSMUST00000237926.2
ENSMUST00000096570.4
Gm94
predicted gene 94
chr19_+_4022322 3.12 ENSMUST00000143380.3
Aldh3b2
aldehyde dehydrogenase 3 family, member B2
chr15_-_88863210 3.12 ENSMUST00000042594.13
ENSMUST00000109368.2
Mlc1
megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)
chr11_+_62465304 3.05 ENSMUST00000018651.14
Trpv2
transient receptor potential cation channel, subfamily V, member 2
chr2_+_181322077 2.92 ENSMUST00000103042.10
Tcea2
transcription elongation factor A (SII), 2
chr5_-_103247920 2.78 ENSMUST00000112848.8
Mapk10
mitogen-activated protein kinase 10
chr7_-_144292288 2.68 ENSMUST00000238848.2
ENSMUST00000118556.9
ENSMUST00000033393.15
Ano1
anoctamin 1, calcium activated chloride channel
chr2_-_125348305 2.60 ENSMUST00000028633.13
Fbn1
fibrillin 1
chrX_-_74918709 2.56 ENSMUST00000114059.10
Pls3
plastin 3 (T-isoform)
chr17_+_47604995 2.54 ENSMUST00000190020.4
Trerf1
transcriptional regulating factor 1
chr1_-_169938298 2.53 ENSMUST00000192312.6
Ddr2
discoidin domain receptor family, member 2
chr9_+_36744016 2.36 ENSMUST00000214772.2
Fez1
fasciculation and elongation protein zeta 1 (zygin I)
chr2_-_32976378 2.31 ENSMUST00000049618.9
Garnl3
GTPase activating RANGAP domain-like 3
chr14_+_9646630 2.30 ENSMUST00000112658.8
ENSMUST00000112657.9
ENSMUST00000177814.2
ENSMUST00000067491.14
Cadps
Ca2+-dependent secretion activator
chrX_+_72235828 2.29 ENSMUST00000101486.5
Xlr3b
X-linked lymphocyte-regulated 3B
chrX_-_8072714 2.23 ENSMUST00000089403.10
ENSMUST00000077595.12
ENSMUST00000089402.10
ENSMUST00000082320.12
Porcn
porcupine O-acyltransferase
chrX_+_142301572 2.23 ENSMUST00000033640.14
Pak3
p21 (RAC1) activated kinase 3
chr16_-_14109219 2.17 ENSMUST00000230397.2
ENSMUST00000231567.2
ENSMUST00000090287.5
Myh11
myosin, heavy polypeptide 11, smooth muscle
chr4_+_136011969 2.12 ENSMUST00000144217.8
Zfp46
zinc finger protein 46
chr7_+_24561616 2.04 ENSMUST00000170837.3
Gm9844
predicted pseudogene 9844
chr15_-_79048674 1.95 ENSMUST00000230261.2
ENSMUST00000040019.5
Sox10
SRY (sex determining region Y)-box 10
chrX_+_21350783 1.95 ENSMUST00000089188.9
Agtr2
angiotensin II receptor, type 2
chr2_-_114485421 1.89 ENSMUST00000028640.14
ENSMUST00000102542.10
Dph6
diphthamine biosynthesis 6
chr19_+_53128861 1.87 ENSMUST00000111741.10
Add3
adducin 3 (gamma)
chr15_+_78481247 1.78 ENSMUST00000043069.6
ENSMUST00000231180.2
ENSMUST00000229796.2
ENSMUST00000229295.2
Cyth4
cytohesin 4
chr15_-_50753061 1.73 ENSMUST00000165201.9
ENSMUST00000184458.8
Trps1
transcriptional repressor GATA binding 1
chr3_+_95532282 1.73 ENSMUST00000058230.13
ENSMUST00000037983.6
Ensa
endosulfine alpha
chr13_+_75237939 1.72 ENSMUST00000022075.6
Pcsk1
proprotein convertase subtilisin/kexin type 1
chr9_-_101076198 1.71 ENSMUST00000066773.9
Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr1_-_74974707 1.71 ENSMUST00000094844.4
Cfap65
cilia and flagella associated protein 65
chr11_-_18968955 1.57 ENSMUST00000068264.14
ENSMUST00000185131.8
Meis1
Meis homeobox 1
chr1_-_155910546 1.56 ENSMUST00000169241.8
Tor1aip1
torsin A interacting protein 1
chr7_-_144292257 1.55 ENSMUST00000121758.8
Ano1
anoctamin 1, calcium activated chloride channel
chr13_+_109769294 1.52 ENSMUST00000135275.8
Pde4d
phosphodiesterase 4D, cAMP specific
chr4_+_147216495 1.42 ENSMUST00000084149.10
Zfp991
zinc finger protein 991
chr6_+_136495784 1.39 ENSMUST00000032335.13
ENSMUST00000185724.7
Atf7ip
activating transcription factor 7 interacting protein
chr2_+_158509039 1.37 ENSMUST00000045503.11
Ppp1r16b
protein phosphatase 1, regulatory subunit 16B
chr15_+_80861966 1.37 ENSMUST00000139517.9
ENSMUST00000137255.3
ENSMUST00000137004.2
Sgsm3
small G protein signaling modulator 3
chr5_-_121641461 1.37 ENSMUST00000079368.5
Adam1b
a disintegrin and metallopeptidase domain 1b
chr4_+_136012019 1.36 ENSMUST00000130223.8
Zfp46
zinc finger protein 46
chr10_-_63926044 1.35 ENSMUST00000105439.2
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr7_-_64575308 1.34 ENSMUST00000149851.8
Fam189a1
family with sequence similarity 189, member A1
chr1_-_84912810 1.32 ENSMUST00000027422.7
Slc16a14
solute carrier family 16 (monocarboxylic acid transporters), member 14
chr10_+_119655294 1.26 ENSMUST00000105262.9
ENSMUST00000147454.8
ENSMUST00000138410.8
ENSMUST00000144825.8
ENSMUST00000148954.8
ENSMUST00000144959.8
Grip1
glutamate receptor interacting protein 1
chr2_-_114485342 1.23 ENSMUST00000055144.8
Dph6
diphthamine biosynthesis 6
chr2_-_131170902 1.23 ENSMUST00000110194.8
Rnf24
ring finger protein 24
chr2_+_22785534 1.22 ENSMUST00000053729.14
Pdss1
prenyl (solanesyl) diphosphate synthase, subunit 1
chrX_+_9066105 1.22 ENSMUST00000069763.3
Lancl3
LanC lantibiotic synthetase component C-like 3 (bacterial)
chrM_+_3906 1.13 ENSMUST00000082396.1
mt-Nd2
mitochondrially encoded NADH dehydrogenase 2
chr4_+_102427247 1.13 ENSMUST00000097950.9
Pde4b
phosphodiesterase 4B, cAMP specific
chr4_+_118522716 1.10 ENSMUST00000102666.5
Olfr62
olfactory receptor 62
chr18_-_84104574 1.08 ENSMUST00000175783.3
Tshz1
teashirt zinc finger family member 1
chr5_+_63957805 1.07 ENSMUST00000162757.4
Nwd2
NACHT and WD repeat domain containing 2
chr5_+_124690908 1.06 ENSMUST00000071057.14
ENSMUST00000111438.2
Ddx55
DEAD box helicase 55
chr2_+_158508609 1.00 ENSMUST00000103116.10
Ppp1r16b
protein phosphatase 1, regulatory subunit 16B
chr8_-_85500010 0.94 ENSMUST00000109764.8
Nfix
nuclear factor I/X
chr11_+_87017878 0.93 ENSMUST00000041282.13
Trim37
tripartite motif-containing 37
chrM_+_11735 0.92 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chrX_+_142301666 0.89 ENSMUST00000134402.8
Pak3
p21 (RAC1) activated kinase 3
chr11_-_18968714 0.85 ENSMUST00000177417.8
Meis1
Meis homeobox 1
chr6_+_136495818 0.84 ENSMUST00000186577.7
Atf7ip
activating transcription factor 7 interacting protein
chr7_+_78563513 0.80 ENSMUST00000038142.15
Isg20
interferon-stimulated protein
chr15_+_80862074 0.73 ENSMUST00000229727.2
Sgsm3
small G protein signaling modulator 3
chr8_-_83129134 0.70 ENSMUST00000209363.2
Il15
interleukin 15
chr4_+_146695418 0.70 ENSMUST00000130825.8
Zfp993
zinc finger protein 993
chr7_+_78563184 0.69 ENSMUST00000121645.8
Isg20
interferon-stimulated protein
chr18_+_58969739 0.69 ENSMUST00000052907.7
Adamts19
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 19
chr2_+_22785593 0.68 ENSMUST00000152170.8
Pdss1
prenyl (solanesyl) diphosphate synthase, subunit 1
chr18_-_84104507 0.64 ENSMUST00000060303.10
Tshz1
teashirt zinc finger family member 1
chr15_-_59245998 0.60 ENSMUST00000022976.6
Washc5
WASH complex subunit 5
chr16_-_45664591 0.59 ENSMUST00000076333.12
Phldb2
pleckstrin homology like domain, family B, member 2
chr6_+_113460258 0.59 ENSMUST00000032422.6
Creld1
cysteine-rich with EGF-like domains 1
chr1_+_153628598 0.53 ENSMUST00000182538.3
Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr6_+_47854138 0.51 ENSMUST00000061890.8
Zfp282
zinc finger protein 282
chr10_+_21870565 0.50 ENSMUST00000020145.12
Sgk1
serum/glucocorticoid regulated kinase 1
chr7_+_7174315 0.49 ENSMUST00000051435.8
Zfp418
zinc finger protein 418
chr7_+_78563150 0.48 ENSMUST00000118867.8
Isg20
interferon-stimulated protein
chr4_+_155915729 0.48 ENSMUST00000139651.8
ENSMUST00000084097.12
Aurkaip1
aurora kinase A interacting protein 1
chr4_+_150366028 0.47 ENSMUST00000105682.9
Rere
arginine glutamic acid dipeptide (RE) repeats
chr7_+_102246977 0.44 ENSMUST00000215712.2
Olfr552
olfactory receptor 552
chr13_+_23922783 0.42 ENSMUST00000040914.3
H1f2
H1.2 linker histone, cluster member
chr10_+_127256993 0.41 ENSMUST00000170336.8
R3hdm2
R3H domain containing 2
chr10_-_129509659 0.40 ENSMUST00000213294.2
ENSMUST00000216067.3
ENSMUST00000203424.2
Olfr801
olfactory receptor 801
chr9_-_48747232 0.40 ENSMUST00000093852.5
Zbtb16
zinc finger and BTB domain containing 16
chr10_-_67384898 0.40 ENSMUST00000075686.7
Ado
2-aminoethanethiol (cysteamine) dioxygenase
chr13_-_55676334 0.39 ENSMUST00000047877.5
Dok3
docking protein 3
chr7_+_43057611 0.34 ENSMUST00000005592.7
Siglecg
sialic acid binding Ig-like lectin G
chr17_+_35327255 0.29 ENSMUST00000037849.3
Ly6g5c
lymphocyte antigen 6 complex, locus G5C
chrX_-_9529189 0.29 ENSMUST00000033519.3
Dynlt3
dynein light chain Tctex-type 3
chr1_+_21419819 0.27 ENSMUST00000088407.4
Khdc1a
KH domain containing 1A
chr19_+_55169148 0.27 ENSMUST00000154886.8
ENSMUST00000120936.8
ENSMUST00000025936.12
Tectb
tectorin beta
chr8_-_22966831 0.24 ENSMUST00000163774.3
ENSMUST00000033935.16
Smim19
small integral membrane protein 19
chr6_-_130170075 0.24 ENSMUST00000112032.8
ENSMUST00000071554.3
Klra9
killer cell lectin-like receptor subfamily A, member 9
chr11_-_58346806 0.23 ENSMUST00000055204.6
Olfr30
olfactory receptor 30
chr17_+_34457868 0.21 ENSMUST00000095342.11
ENSMUST00000167280.8
ENSMUST00000236838.2
H2-Ob
histocompatibility 2, O region beta locus
chr7_-_103928939 0.21 ENSMUST00000051795.10
Trim5
tripartite motif-containing 5
chr13_+_21901791 0.21 ENSMUST00000188775.2
H3c10
H3 clustered histone 10
chr10_+_129153986 0.20 ENSMUST00000215503.2
Olfr780
olfactory receptor 780
chr11_+_106916430 0.16 ENSMUST00000140447.4
1810010H24Rik
RIKEN cDNA 1810010H24 gene
chrX_-_153911405 0.15 ENSMUST00000076671.4
Cldn34b2
claudin 34B2
chr6_+_65567373 0.14 ENSMUST00000114236.2
Tnip3
TNFAIP3 interacting protein 3
chr16_-_45664664 0.12 ENSMUST00000036355.13
Phldb2
pleckstrin homology like domain, family B, member 2
chr9_-_57065572 0.11 ENSMUST00000065358.9
Commd4
COMM domain containing 4
chr19_-_10460238 0.10 ENSMUST00000235392.2
ENSMUST00000237522.2
ENSMUST00000038842.5
Ppp1r32
protein phosphatase 1, regulatory subunit 32
chr7_-_102591782 0.10 ENSMUST00000210571.2
ENSMUST00000064830.6
Olfr573-ps1
olfactory receptor 573, pseudogene 1
chr9_+_96141299 0.09 ENSMUST00000179065.8
Tfdp2
transcription factor Dp 2
chr9_+_96141317 0.09 ENSMUST00000165768.4
Tfdp2
transcription factor Dp 2
chr4_+_6365694 0.08 ENSMUST00000175769.8
ENSMUST00000140830.8
ENSMUST00000108374.8
Sdcbp
syndecan binding protein
chr5_-_116427003 0.07 ENSMUST00000086483.4
ENSMUST00000050178.13
Ccdc60
coiled-coil domain containing 60
chr4_+_6365650 0.07 ENSMUST00000029912.11
ENSMUST00000103008.12
Sdcbp
syndecan binding protein
chr7_-_104246386 0.07 ENSMUST00000057385.5
Olfr655
olfactory receptor 655
chr2_-_89491560 0.05 ENSMUST00000111527.4
Olfr1250
olfactory receptor 1250
chr9_+_18848418 0.05 ENSMUST00000218385.2
Olfr832
olfactory receptor 832
chr16_-_58747023 0.04 ENSMUST00000205742.2
Olfr181
olfactory receptor 181
chr10_+_127257077 0.03 ENSMUST00000168780.8
R3hdm2
R3H domain containing 2
chr3_+_20111958 0.02 ENSMUST00000002502.12
Hltf
helicase-like transcription factor
chr2_+_73102269 0.01 ENSMUST00000090813.6
Sp9
trans-acting transcription factor 9

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.2 GO:0072313 metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
2.2 6.5 GO:0061107 seminal vesicle development(GO:0061107)
1.9 19.5 GO:0042866 pyruvate biosynthetic process(GO:0042866)
1.0 5.9 GO:0007412 axon target recognition(GO:0007412)
1.0 3.9 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
0.6 2.6 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.6 2.4 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.6 2.3 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.5 1.9 GO:0035566 regulation of metanephros size(GO:0035566)
0.4 7.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.4 2.8 GO:0007258 JUN phosphorylation(GO:0007258)
0.4 4.2 GO:0015705 iodide transport(GO:0015705)
0.4 4.9 GO:0006527 arginine catabolic process(GO:0006527)
0.3 2.0 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.3 2.1 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.3 3.1 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.2 1.7 GO:0060023 soft palate development(GO:0060023)
0.2 1.7 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.2 1.9 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.2 2.6 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 2.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 2.5 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.7 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 1.6 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.9 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 8.3 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.1 0.5 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.1 0.7 GO:0035723 interleukin-15-mediated signaling pathway(GO:0035723) extrathymic T cell selection(GO:0045062) cellular response to interleukin-15(GO:0071350)
0.1 5.4 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 3.9 GO:0097352 autophagosome maturation(GO:0097352)
0.1 2.4 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.1 2.6 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.4 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 1.9 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.1 0.6 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038) spindle assembly involved in meiosis(GO:0090306)
0.1 2.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.2 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.1 1.4 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 1.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.7 GO:0016486 peptide hormone processing(GO:0016486)
0.1 1.5 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 1.8 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.9 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 3.1 GO:0090280 positive regulation of calcium ion import(GO:0090280)
0.0 2.7 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.5 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 3.1 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 3.5 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 0.2 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.5 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 2.2 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 1.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 2.2 GO:0006497 protein lipidation(GO:0006497)
0.0 1.7 GO:0035308 negative regulation of protein dephosphorylation(GO:0035308)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.5 19.5 GO:1902912 pyruvate kinase complex(GO:1902912)
0.4 8.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 2.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 3.1 GO:0032584 growth cone membrane(GO:0032584)
0.2 3.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.2 2.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.9 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 2.3 GO:0031045 dense core granule(GO:0031045)
0.1 8.2 GO:0005581 collagen trimer(GO:0005581)
0.1 4.2 GO:0034707 chloride channel complex(GO:0034707)
0.1 1.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 3.5 GO:0045171 intercellular bridge(GO:0045171)
0.0 2.1 GO:0005921 gap junction(GO:0005921)
0.0 2.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 2.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.6 GO:0071203 WASH complex(GO:0071203)
0.0 0.7 GO:0045180 basal cortex(GO:0045180)
0.0 2.0 GO:0015030 Cajal body(GO:0015030)
0.0 0.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 2.6 GO:0032420 stereocilium(GO:0032420)
0.0 3.1 GO:0005811 lipid particle(GO:0005811)
0.0 3.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 4.1 GO:0055037 recycling endosome(GO:0055037)
0.0 0.2 GO:1990462 omegasome(GO:1990462)
0.0 5.9 GO:0044306 neuron projection terminus(GO:0044306)
0.0 3.5 GO:0008021 synaptic vesicle(GO:0008021)
0.0 2.8 GO:0043204 perikaryon(GO:0043204)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 7.5 GO:0005874 microtubule(GO:0005874)
0.0 2.6 GO:0000794 condensed nuclear chromosome(GO:0000794)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 19.5 GO:0004743 pyruvate kinase activity(GO:0004743)
1.5 5.9 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
1.0 3.9 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.7 8.2 GO:0033691 sialic acid binding(GO:0033691)
0.7 2.2 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.7 4.2 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.6 2.8 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.5 1.9 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.4 4.9 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.4 2.0 GO:0008859 exoribonuclease II activity(GO:0008859)
0.4 1.9 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.3 3.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.2 2.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 8.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 3.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 3.5 GO:0031489 myosin V binding(GO:0031489)
0.1 3.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 2.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.7 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 0.5 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 2.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.6 GO:0005521 lamin binding(GO:0005521)
0.1 0.2 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 1.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 6.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 2.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 7.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.9 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 2.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 6.1 GO:0051015 actin filament binding(GO:0051015)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 3.1 GO:0008565 protein transporter activity(GO:0008565)
0.0 1.9 GO:0005080 protein kinase C binding(GO:0005080)
0.0 3.1 GO:0005262 calcium channel activity(GO:0005262)
0.0 2.4 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 1.3 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.1 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 1.9 GO:0030674 protein binding, bridging(GO:0030674)
0.0 1.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.3 PID RAS PATHWAY Regulation of Ras family activation
0.1 5.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 3.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 2.8 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 8.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 5.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.5 PID AURORA A PATHWAY Aurora A signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.2 1.7 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.1 2.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 8.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 3.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 2.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 2.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling