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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Pbx2

Z-value: 0.80

Motif logo

Transcription factors associated with Pbx2

Gene Symbol Gene ID Gene Info
ENSMUSG00000034673.15 Pbx2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pbx2mm39_v1_chr17_+_34812361_34812384-0.104.1e-01Click!

Activity profile of Pbx2 motif

Sorted Z-values of Pbx2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Pbx2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr9_+_95441652 4.48 ENSMUST00000079597.7
progestin and adipoQ receptor family member IX
chr4_-_61972348 4.06 ENSMUST00000074018.4
major urinary protein 20
chr8_-_71257623 3.54 ENSMUST00000212875.2
ENSMUST00000212001.2
ENSMUST00000212757.2
microtubule associated serine/threonine kinase 3
chr17_+_7437500 3.21 ENSMUST00000024575.8
ribosomal protein S6 kinase, polypeptide 2
chr13_-_113800172 3.07 ENSMUST00000054650.5
heat shock protein 3
chr7_-_46392403 2.98 ENSMUST00000128088.4
serum amyloid A 1
chr8_-_55177510 2.92 ENSMUST00000175915.8
WD repeat domain 17
chr13_-_24098981 2.65 ENSMUST00000110407.4
solute carrier family 17 (sodium phosphate), member 4
chr11_-_99134885 2.63 ENSMUST00000103132.10
ENSMUST00000038214.7
keratin 222
chr10_+_97482946 2.59 ENSMUST00000105285.4
epiphycan
chr7_-_43155351 2.52 ENSMUST00000191516.7
ENSMUST00000013497.8
ENSMUST00000163619.8
RIKEN cDNA 4931406B18 gene
chr13_-_25454058 2.50 ENSMUST00000057866.13
neurensin 1
chr13_-_24098951 2.49 ENSMUST00000021769.16
solute carrier family 17 (sodium phosphate), member 4
chr3_+_130411097 2.47 ENSMUST00000166187.8
ENSMUST00000072271.13
ethanolamine phosphate phospholyase
chr2_-_57942844 2.45 ENSMUST00000090940.6
ermin, ERM-like protein
chr10_-_63039709 2.39 ENSMUST00000095580.3
myopalladin
chr11_-_79394904 2.35 ENSMUST00000164465.3
oligodendrocyte myelin glycoprotein
chr19_-_5168251 2.34 ENSMUST00000113728.8
ENSMUST00000113727.8
ENSMUST00000025798.13
kinesin light chain 2
chr15_+_21111428 2.29 ENSMUST00000075132.8
cadherin 12
chr2_+_65451100 2.28 ENSMUST00000144254.6
ENSMUST00000028377.14
sodium channel, voltage-gated, type II, alpha
chr4_+_102843540 2.16 ENSMUST00000030248.12
ENSMUST00000125417.9
ENSMUST00000169211.3
dynein light chain Tctex-type 5
chrX_+_72108393 2.13 ENSMUST00000060418.8
paraneoplastic antigen MA3
chr7_+_46401214 2.07 ENSMUST00000210769.2
ENSMUST00000210272.2
ENSMUST00000075982.4
serum amyloid A 2
chr18_-_23171713 2.04 ENSMUST00000081423.13
nucleolar protein 4
chr1_+_66426127 1.97 ENSMUST00000145419.8
microtubule-associated protein 2
chr6_+_8259288 1.85 ENSMUST00000159335.8
UMAP1-MVP12 associated (UMA) domain containing 1
chr4_-_116485118 1.73 ENSMUST00000030456.14
nuclear autoantigenic sperm protein (histone-binding)
chr6_-_129303659 1.73 ENSMUST00000203159.2
C-type lectin domain family 2, member m
chr3_-_88679881 1.67 ENSMUST00000090945.5
synaptotagmin XI
chr1_+_60948149 1.57 ENSMUST00000027164.9
cytotoxic T-lymphocyte-associated protein 4
chr3_+_124114504 1.56 ENSMUST00000058994.6
translocation associated membrane protein 1-like 1
chr7_-_43155118 1.55 ENSMUST00000168883.2
RIKEN cDNA 4931406B18 gene
chr15_+_16778187 1.53 ENSMUST00000026432.8
cadherin 9
chr12_+_108145802 1.43 ENSMUST00000221167.2
cyclin K
chr1_+_169756217 1.43 ENSMUST00000094348.4
coiled-coil domain containing 190
chr2_-_34951443 1.42 ENSMUST00000028233.7
hemolytic complement
chr7_-_3298243 1.38 ENSMUST00000108653.4
NLR family, pyrin domain containing 12
chr9_-_70841881 1.36 ENSMUST00000214995.2
lipase, hepatic
chr11_-_99313078 1.34 ENSMUST00000017741.4
keratin 12
chr17_-_52140305 1.34 ENSMUST00000133574.8
special AT-rich sequence binding protein 1
chr17_+_35454049 1.34 ENSMUST00000130992.2
ATPase, H+ transporting, lysosomal V1 subunit G2
chr19_+_8897732 1.34 ENSMUST00000096243.7
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr19_+_39980868 1.33 ENSMUST00000049178.3
cytochrome P450, family 2. subfamily c, polypeptide 37
chr7_-_66915756 1.33 ENSMUST00000207715.2
myocyte enhancer factor 2A
chr15_+_92495007 1.29 ENSMUST00000035399.10
PDZ domain containing RING finger 4
chr1_-_160986880 1.28 ENSMUST00000135643.8
ENSMUST00000178511.3
testis expressed 50
chr3_-_152687877 1.27 ENSMUST00000044278.6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr16_+_88954838 1.22 ENSMUST00000062524.6
predicted gene 9789
chr2_-_110591909 1.21 ENSMUST00000140777.2
anoctamin 3
chr12_+_103547657 1.21 ENSMUST00000190664.2
protein phosphatase 4, regulatory subunit 4
chr9_-_70842090 1.20 ENSMUST00000034731.10
lipase, hepatic
chrX_-_43879055 1.19 ENSMUST00000060481.9
DDB1 and CUL4 associated factor 12-like 1
chr15_-_100945261 1.17 ENSMUST00000222611.2
transmembrane and death domain 1
chr1_+_85945790 1.12 ENSMUST00000149469.3
spermatogenesis associated 3
chr6_-_127086480 1.11 ENSMUST00000039913.9
Trp53 induced glycolysis regulatory phosphatase
chr5_-_87288177 1.11 ENSMUST00000067790.7
UDP glucuronosyltransferase 2 family, polypeptide B5
chr11_+_58311921 1.08 ENSMUST00000013797.3
RIKEN cDNA 1810065E05 gene
chr16_-_37205277 1.07 ENSMUST00000114787.8
ENSMUST00000114782.8
ENSMUST00000114775.8
syntaxin binding protein 5-like
chr9_+_110948492 1.04 ENSMUST00000217341.3
leucine rich repeat (in FLII) interacting protein 2
chr17_+_9068805 1.03 ENSMUST00000115720.8
phosphodiesterase 10A
chr16_-_37205302 1.03 ENSMUST00000114781.8
ENSMUST00000114780.8
syntaxin binding protein 5-like
chr9_+_92191415 1.00 ENSMUST00000150594.8
ENSMUST00000098477.8
RIKEN cDNA 1700057G04 gene
chr7_-_103778992 0.99 ENSMUST00000053743.6
ubiquilin 5
chr16_+_45355654 0.98 ENSMUST00000159945.8
solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1
chr11_+_5519677 0.96 ENSMUST00000109856.8
ENSMUST00000109855.8
ENSMUST00000118112.9
ankyrin repeat domain 36
chrX_+_115358631 0.93 ENSMUST00000101269.2
CPX chromosome region, candidate 1
chr1_-_130557349 0.93 ENSMUST00000142416.2
ENSMUST00000039862.11
ENSMUST00000128128.8
zona pellucida 3 receptor
chrX_+_68988904 0.93 ENSMUST00000075654.2
RIKEN cDNA 1700020N15 gene
chr2_+_106525938 0.91 ENSMUST00000016530.14
metallophosphoesterase domain containing 2
chr12_-_46767619 0.90 ENSMUST00000219886.2
NOVA alternative splicing regulator 1
chr6_-_3988900 0.89 ENSMUST00000183682.3
tissue factor pathway inhibitor 2
chr4_+_132495636 0.85 ENSMUST00000102561.11
replication protein A2
chr14_+_14986011 0.85 ENSMUST00000164366.8
predicted gene 3752
chr1_+_60948307 0.83 ENSMUST00000097720.4
cytotoxic T-lymphocyte-associated protein 4
chr11_+_88964667 0.82 ENSMUST00000100619.11
predicted gene 525
chr3_+_122688721 0.82 ENSMUST00000023820.6
fatty acid binding protein 2, intestinal
chr2_-_151510453 0.80 ENSMUST00000180195.8
ENSMUST00000096439.4
RAD21-like (S. pombe)
chr11_-_72106418 0.79 ENSMUST00000021157.9
mediator complex subunit 31
chr17_-_53846438 0.78 ENSMUST00000056198.4
protein phosphatase 2C-like domain containing 1
chr15_-_98118858 0.77 ENSMUST00000142443.8
ENSMUST00000170618.8
predicted gene 44579
olfactory receptor 287
chr10_+_57521930 0.76 ENSMUST00000177325.8
protein kinase inhibitor beta, cAMP dependent, testis specific
chr3_+_68479578 0.75 ENSMUST00000170788.9
schwannomin interacting protein 1
chr13_+_21901791 0.75 ENSMUST00000188775.2
H3 clustered histone 10
chr16_-_38649107 0.74 ENSMUST00000122078.3
testis expressed 55
chr4_+_147637714 0.73 ENSMUST00000139784.8
ENSMUST00000143885.8
ENSMUST00000081742.7
zinc finger protein 985
chr9_-_58277734 0.72 ENSMUST00000040217.6
TBC1 domain family, member 21
chr13_-_99653045 0.70 ENSMUST00000064762.6
microtubule-associated protein 1B
chr1_+_53100796 0.70 ENSMUST00000027269.7
ENSMUST00000191197.2
myostatin
chrX_-_74621828 0.70 ENSMUST00000033545.6
RAB39B, member RAS oncogene family
chr16_+_96081998 0.69 ENSMUST00000099497.4
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
chr15_+_77361241 0.69 ENSMUST00000060551.9
apolipoprotein L 10A
chrX_-_121307036 0.68 ENSMUST00000079490.6
nucleosome assembly protein 1-like 3
chr6_+_78347636 0.68 ENSMUST00000204873.3
regenerating islet-derived 3 beta
chr19_-_13126896 0.68 ENSMUST00000213493.2
olfactory receptor 1459
chrX_+_162694397 0.65 ENSMUST00000140845.2
adaptor-related protein complex 1, sigma 2 subunit
chr11_-_115599370 0.65 ENSMUST00000106495.8
growth factor receptor bound protein 2
chrX_-_67936659 0.64 ENSMUST00000074894.2
predicted gene 6812
chr11_-_60770098 0.64 ENSMUST00000062677.12
transmembrane protein 11
chr2_-_177567397 0.63 ENSMUST00000108934.9
ENSMUST00000081529.11
zinc finger protein 972
chr18_+_37858753 0.63 ENSMUST00000066149.9
protocadherin gamma subfamily A, 8
chr13_-_23929490 0.63 ENSMUST00000091752.5
H3 clustered histone 3
chr1_+_136552639 0.62 ENSMUST00000047734.15
ENSMUST00000112046.2
zinc finger protein 281
chr15_+_77392466 0.62 ENSMUST00000172191.3
apolipoprotein L 11a
chr17_+_85265420 0.61 ENSMUST00000080217.14
ENSMUST00000112304.10
protein phosphatase 1B, magnesium dependent, beta isoform
chr2_-_101451383 0.59 ENSMUST00000090513.11
intraflagellar transport associated protein
chr4_+_146586445 0.59 ENSMUST00000105735.9
zinc finger protein 981
chr7_+_18451998 0.59 ENSMUST00000051973.9
ENSMUST00000208221.2
ENSMUST00000108481.8
pregnancy-specific glycoprotein 22
chr2_+_29014106 0.59 ENSMUST00000129544.8
senataxin
chr3_+_20011201 0.59 ENSMUST00000091309.12
ENSMUST00000108329.8
ENSMUST00000003714.13
ceruloplasmin
chr9_-_6269846 0.59 ENSMUST00000051706.6
DNA-damage inducible 1
chr17_+_24692858 0.59 ENSMUST00000054946.10
ENSMUST00000238986.2
ENSMUST00000164508.2
BRICHOS domain containing 5
chr18_+_44960813 0.58 ENSMUST00000037763.11
YTH domain containing 2
chr10_+_57521958 0.57 ENSMUST00000177473.8
protein kinase inhibitor beta, cAMP dependent, testis specific
chr11_+_60244132 0.57 ENSMUST00000070805.13
ENSMUST00000094140.9
ENSMUST00000108723.9
ENSMUST00000108722.5
dynein regulatory complex subunit 3
chr18_+_3383230 0.56 ENSMUST00000162301.8
ENSMUST00000161317.2
cullin 2
chr7_+_6048160 0.56 ENSMUST00000037728.13
ENSMUST00000121583.2
NLR family, pyrin domain containing 4C
chr7_-_18165959 0.55 ENSMUST00000019291.7
pregnancy-specific glycoprotein 28
chr2_-_165242307 0.54 ENSMUST00000029213.5
osteoclast stimulatory transmembrane protein
chr8_+_41246310 0.54 ENSMUST00000056331.8
a disintegrin and metallopeptidase domain 20
chr2_+_128809268 0.54 ENSMUST00000110320.9
ENSMUST00000110319.3
zinc finger CCCH type containing 6
chr7_-_121700958 0.54 ENSMUST00000139456.2
ENSMUST00000106471.9
ENSMUST00000123296.8
ENSMUST00000033157.10
NADH:ubiquinone oxidoreductase subunit AB1
chr6_+_116627635 0.52 ENSMUST00000204555.2
DEPP1 autophagy regulator
chr13_-_86194889 0.51 ENSMUST00000131011.2
cytochrome c oxidase subunit 7C
chr5_-_122492223 0.51 ENSMUST00000117263.8
ENSMUST00000049009.7
RAD9 checkpoint clamp component B
chr17_-_35265702 0.49 ENSMUST00000097338.11
mutS homolog 5
chr7_-_103142086 0.49 ENSMUST00000055787.8
olfactory receptor 609
chr1_-_130839178 0.46 ENSMUST00000027673.11
interleukin 20
chr7_+_106737534 0.46 ENSMUST00000213367.3
ENSMUST00000214819.3
ENSMUST00000216871.3
ENSMUST00000215284.3
ENSMUST00000209942.2
olfactory receptor 716
chr3_-_107850707 0.46 ENSMUST00000106681.3
glutathione S-transferase, mu 6
chr17_+_78815493 0.46 ENSMUST00000024880.11
ENSMUST00000232859.2
vitrin
chr2_+_109522781 0.46 ENSMUST00000111050.10
brain derived neurotrophic factor
chr13_-_43324937 0.44 ENSMUST00000222160.2
ENSMUST00000179852.9
ENSMUST00000021797.9
TBC1 domain family, member 7
chr6_-_23655130 0.44 ENSMUST00000104979.2
ring finger protein 148
chr4_+_146599377 0.44 ENSMUST00000140089.7
ENSMUST00000179175.3
zinc finger protein 981
chr11_-_99494134 0.44 ENSMUST00000072306.4
predicted gene 11938
chr6_+_8259328 0.43 ENSMUST00000159378.8
UMAP1-MVP12 associated (UMA) domain containing 1
chr14_+_54429757 0.41 ENSMUST00000103714.2
T cell receptor alpha joining 27
chr4_+_147106307 0.40 ENSMUST00000075775.6
reduced expression 2
chr5_-_3697806 0.40 ENSMUST00000119783.2
ENSMUST00000007559.15
GATA zinc finger domain containing 1
chrX_+_126301916 0.40 ENSMUST00000051530.4
RIKEN cDNA 4921511C20 gene
chr8_-_85567256 0.40 ENSMUST00000003911.13
ENSMUST00000109761.9
ENSMUST00000128035.2
RAD23 homolog A, nucleotide excision repair protein
chr14_+_53194239 0.40 ENSMUST00000199800.2
T cell receptor alpha variable 15D-2-DV6D-2
chr14_+_53310461 0.40 ENSMUST00000103607.3
T cell receptor alpha variable 13D-4
chr16_-_19241884 0.40 ENSMUST00000206110.4
olfactory receptor 165
chr18_-_77134939 0.40 ENSMUST00000137354.8
ENSMUST00000137498.8
katanin p60 subunit A-like 2
chr18_-_44292952 0.39 ENSMUST00000181652.9
predicted gene 10267
chr6_+_41112064 0.39 ENSMUST00000103272.4
T cell receptor beta, variable 14
chr7_+_102526329 0.39 ENSMUST00000098216.2
olfactory receptor 568
chr5_-_72893941 0.38 ENSMUST00000169534.6
TXK tyrosine kinase
chr7_-_12829100 0.38 ENSMUST00000209822.3
ENSMUST00000235753.2
vomeronasal 1 receptor 85
chr4_+_146093394 0.38 ENSMUST00000168483.9
zinc finger protein 600
chr13_+_60749735 0.38 ENSMUST00000226059.2
ENSMUST00000077453.13
death associated protein kinase 1
chr7_+_43256593 0.37 ENSMUST00000120935.2
ENSMUST00000127765.8
ENSMUST00000032661.14
zinc finger protein 819
chr14_+_53574579 0.37 ENSMUST00000179580.3
T cell receptor alpha variable 13N-3
chr4_+_145397238 0.37 ENSMUST00000105738.9
zinc finger protein 980
chr8_+_22436766 0.36 ENSMUST00000060587.4
defensin beta 13
chr8_+_66964401 0.36 ENSMUST00000002025.5
ENSMUST00000183187.2
transketolase-like 2
chrX_+_18012089 0.35 ENSMUST00000026018.4
dual specificity phosphatase 21
chr5_-_6926523 0.35 ENSMUST00000164784.2
zinc finger protein 804B
chr2_-_89172742 0.35 ENSMUST00000216561.2
olfactory receptor 1233
chrX_+_8970801 0.35 ENSMUST00000059967.2
RIKEN cDNA 4930402K13 gene
chr15_+_41573995 0.35 ENSMUST00000229769.2
oxidation resistance 1
chr18_+_37813286 0.34 ENSMUST00000192931.2
protocadherin gamma subfamily B, 1
chr12_-_103392039 0.34 ENSMUST00000110001.4
ENSMUST00000223233.2
ENSMUST00000044923.15
ENSMUST00000221211.2
DEAD box helicase 24
chr17_+_37978659 0.34 ENSMUST00000216551.2
olfactory receptor 118
chr8_+_94537910 0.33 ENSMUST00000138659.9
guanine nucleotide binding protein, alpha O
chr12_+_44268134 0.33 ENSMUST00000122902.8
patatin-like phospholipase domain containing 8
chr14_+_53100756 0.33 ENSMUST00000103616.5
ENSMUST00000186370.2
T cell receptor alpha variable 15D-1-DV6D-1
chr11_-_115599418 0.32 ENSMUST00000021090.14
growth factor receptor bound protein 2
chr7_+_133239414 0.31 ENSMUST00000128901.9
erythroid differentiation regulatory factor 1
chr18_-_77134980 0.31 ENSMUST00000154665.2
ENSMUST00000026486.13
ENSMUST00000123650.2
ENSMUST00000126153.8
katanin p60 subunit A-like 2
chr11_-_31621727 0.29 ENSMUST00000109415.2
biorientation of chromosomes in cell division 1
chr3_+_152052102 0.29 ENSMUST00000117492.9
ENSMUST00000026507.13
ENSMUST00000197748.5
ubiquitin specific peptidase 33
chr1_-_181992051 0.29 ENSMUST00000227629.2
ENSMUST00000227586.2
vomeronasal 1 receptor 1
chr7_-_26878260 0.29 ENSMUST00000093040.13
RAB4B, member RAS oncogene family
chr1_-_97689263 0.29 ENSMUST00000171129.8
diphosphoinositol pentakisphosphate kinase 2
chr11_-_99241924 0.29 ENSMUST00000017732.3
keratin 27
chr3_-_107851021 0.28 ENSMUST00000106684.8
ENSMUST00000106685.9
glutathione S-transferase, mu 6
chr1_-_120198804 0.28 ENSMUST00000112641.8
STEAP family member 3
chr14_+_78141679 0.28 ENSMUST00000022591.16
ENSMUST00000169978.2
ENSMUST00000227903.2
epithelial stromal interaction 1 (breast)
chr4_-_147787010 0.27 ENSMUST00000117638.2
zinc finger protein 534
chr3_-_106733603 0.27 ENSMUST00000213616.3
olfactory receptor 266
chr9_-_20371123 0.27 ENSMUST00000162438.2
zinc finger protein 26
chr14_+_54444010 0.27 ENSMUST00000103729.2
T cell receptor alpha joining 12
chr3_+_20011251 0.26 ENSMUST00000108328.8
ceruloplasmin
chr12_-_55349760 0.26 ENSMUST00000021410.10
protein phosphatase 2, regulatory subunit B'', gamma
chrX_-_77289527 0.26 ENSMUST00000114026.3
predicted gene 14743
chr11_+_49138278 0.24 ENSMUST00000109194.2
mannoside acetylglucosaminyltransferase 1
chr12_-_15866763 0.24 ENSMUST00000020922.8
ENSMUST00000221215.2
ENSMUST00000221518.2
tribbles pseudokinase 2
chr4_+_147390131 0.24 ENSMUST00000148762.4
zinc finger protein 988
chr17_+_14168635 0.24 ENSMUST00000088809.6
predicted gene 7168
chr2_+_111985663 0.23 ENSMUST00000058176.7
olfactory receptor 1318
chr10_-_81335966 0.22 ENSMUST00000053646.7
sphingosine-1-phosphate receptor 4
chr11_+_3280771 0.22 ENSMUST00000136536.8
ENSMUST00000093399.11
phosphoinositide-3-kinase interacting protein 1
chr14_+_123897383 0.22 ENSMUST00000049681.14
integrin, beta-like 1
chrX_+_77230380 0.21 ENSMUST00000088198.4
odorant binding protein IB
chr19_-_11833365 0.21 ENSMUST00000079875.4
olfactory receptor 1418
chr4_+_147445744 0.21 ENSMUST00000133078.8
ENSMUST00000154154.2
zinc finger protein 978
chr18_-_84854841 0.21 ENSMUST00000236689.2
predicted gene, 17266
chr7_-_102143980 0.21 ENSMUST00000058750.4
olfactory receptor 545

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.1 GO:0008355 olfactory learning(GO:0008355)
0.5 2.6 GO:0034371 chylomicron remodeling(GO:0034371)
0.5 1.4 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.4 1.7 GO:1990927 negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.4 2.4 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.4 1.1 GO:1904024 negative regulation of NAD metabolic process(GO:1902689) negative regulation of glucose catabolic process to lactate via pyruvate(GO:1904024)
0.3 1.2 GO:0080163 regulation of protein serine/threonine phosphatase activity(GO:0080163)
0.3 1.4 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.3 1.3 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.3 1.3 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.2 3.2 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.2 1.0 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway(GO:0035660)
0.2 2.3 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.2 0.6 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.2 1.4 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.2 0.7 GO:0014732 skeletal muscle atrophy(GO:0014732)
0.2 1.8 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2 0.5 GO:0061193 taste bud development(GO:0061193)
0.2 1.2 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.1 0.6 GO:2001201 regulation of transforming growth factor-beta secretion(GO:2001201)
0.1 1.0 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.5 GO:0034241 positive regulation of macrophage fusion(GO:0034241)
0.1 0.3 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 2.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 2.3 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.1 1.8 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 1.3 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.1 0.8 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 5.4 GO:0006953 acute-phase response(GO:0006953)
0.1 0.6 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 0.6 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.1 1.0 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.2 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 1.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 1.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.2 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 0.4 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 2.7 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.5 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.0 1.0 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 1.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 1.3 GO:0006298 mismatch repair(GO:0006298)
0.0 0.5 GO:0000076 DNA replication checkpoint(GO:0000076) intra-S DNA damage checkpoint(GO:0031573)
0.0 5.1 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 1.0 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.3 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.8 GO:0001553 luteinization(GO:0001553)
0.0 0.4 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 2.1 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 3.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.9 GO:0046688 response to copper ion(GO:0046688)
0.0 0.3 GO:0006020 inositol metabolic process(GO:0006020)
0.0 2.4 GO:0008088 axo-dendritic transport(GO:0008088)
0.0 0.3 GO:1902572 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.8 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 1.3 GO:0015992 proton transport(GO:0015992)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0002945 cyclin K-CDK12 complex(GO:0002944) cyclin K-CDK13 complex(GO:0002945)
0.3 2.4 GO:0033269 internode region of axon(GO:0033269)
0.2 0.9 GO:0043159 acrosomal matrix(GO:0043159)
0.2 2.0 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 7.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 1.4 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.8 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 1.7 GO:0032009 early phagosome(GO:0032009)
0.1 1.0 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 0.5 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.8 GO:0070847 core mediator complex(GO:0070847)
0.1 2.3 GO:0035253 ciliary rootlet(GO:0035253)
0.1 2.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.8 GO:0045179 apical cortex(GO:0045179)
0.1 2.4 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.6 GO:0030891 VCB complex(GO:0030891)
0.0 0.3 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 1.3 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.5 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.7 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 3.5 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.6 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 1.2 GO:1903293 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 3.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.4 GO:0030018 Z disc(GO:0030018)
0.0 3.4 GO:0030426 growth cone(GO:0030426)
0.0 0.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.3 GO:0016605 PML body(GO:0016605)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.8 3.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.5 2.6 GO:0035478 chylomicron binding(GO:0035478)
0.4 4.2 GO:0005186 pheromone activity(GO:0005186)
0.3 5.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.3 2.7 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.2 1.3 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 0.6 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.2 0.5 GO:0031177 phosphopantetheine binding(GO:0031177)
0.2 1.0 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2 0.5 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 2.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 1.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 5.0 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.4 GO:0004802 transketolase activity(GO:0004802)
0.1 0.7 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.1 GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 1.0 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.8 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 2.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 2.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.9 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.0 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 1.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.2 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.9 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.6 GO:0045545 syndecan binding(GO:0045545)
0.1 1.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 1.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.3 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.5 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 1.3 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 4.1 GO:0019905 syntaxin binding(GO:0019905)
0.0 3.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 1.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 2.3 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.7 GO:0031489 myosin V binding(GO:0031489)
0.0 1.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.4 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 1.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.6 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.3 GO:0017160 Ral GTPase binding(GO:0017160)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 1.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 2.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 2.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 2.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.3 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.8 PID ATR PATHWAY ATR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 3.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 4.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 2.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 2.3 REACTOME KINESINS Genes involved in Kinesins
0.1 2.4 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.1 0.8 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 2.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.3 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 1.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.7 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE