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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Pitx1

Z-value: 1.27

Motif logo

Transcription factors associated with Pitx1

Gene Symbol Gene ID Gene Info
ENSMUSG00000021506.8 Pitx1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pitx1mm39_v1_chr13_-_55983946_559840050.318.7e-03Click!

Activity profile of Pitx1 motif

Sorted Z-values of Pitx1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Pitx1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_+_43361930 11.93 ENSMUST00000066834.8
kallikrein related-peptidase 13
chr11_-_99383938 6.34 ENSMUST00000006969.8
keratin 23
chr2_+_121188195 6.17 ENSMUST00000125812.8
ENSMUST00000078222.9
ENSMUST00000125221.3
ENSMUST00000150271.8
creatine kinase, mitochondrial 1, ubiquitous
chr11_-_100012384 5.82 ENSMUST00000007275.3
keratin 13
chr4_-_41697040 5.73 ENSMUST00000102962.10
ciliary neurotrophic factor receptor
chr18_-_32271224 5.11 ENSMUST00000234657.2
ENSMUST00000234386.2
ENSMUST00000234651.2
protein C
chr19_+_8595369 5.07 ENSMUST00000010250.4
solute carrier family 22 (organic anion transporter), member 6
chr18_-_43925932 4.96 ENSMUST00000237926.2
ENSMUST00000096570.4
predicted gene 94
chr3_+_106020545 4.68 ENSMUST00000079132.12
ENSMUST00000139086.2
chitinase, acidic 1
chr11_-_100026754 4.36 ENSMUST00000107411.3
keratin 15
chr11_+_115225557 4.06 ENSMUST00000106543.8
ENSMUST00000019006.5
otopetrin 3
chr15_-_79048674 4.04 ENSMUST00000230261.2
ENSMUST00000040019.5
SRY (sex determining region Y)-box 10
chr7_-_80053063 3.85 ENSMUST00000147150.2
furin (paired basic amino acid cleaving enzyme)
chr11_+_60956624 3.82 ENSMUST00000041944.9
ENSMUST00000108717.3
potassium inwardly-rectifying channel, subfamily J, member 12
chr10_+_69761784 3.79 ENSMUST00000181974.8
ENSMUST00000182795.8
ENSMUST00000182437.8
ankyrin 3, epithelial
chr2_+_14393127 3.62 ENSMUST00000114731.8
ENSMUST00000082290.8
solute carrier family 39 (zinc transporter), member 12
chr2_+_102488985 3.44 ENSMUST00000080210.10
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr18_+_36498826 3.38 ENSMUST00000144158.2
cysteine-rich transmembrane module containing 1
chr10_+_69761597 3.30 ENSMUST00000182269.8
ENSMUST00000183261.8
ENSMUST00000183074.8
ankyrin 3, epithelial
chr7_+_43418321 3.25 ENSMUST00000107970.8
kallikrein related-peptidase 12
chr3_-_33137165 3.23 ENSMUST00000078226.10
ENSMUST00000108224.8
peroxisomal biogenesis factor 5-like
chr10_-_125164399 3.22 ENSMUST00000063318.10
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr1_+_74582044 3.22 ENSMUST00000113749.8
ENSMUST00000067916.13
ENSMUST00000113747.8
ENSMUST00000113750.8
phospholipase C, delta 4
chr1_-_119576347 3.18 ENSMUST00000027632.14
ENSMUST00000187194.2
erythrocyte membrane protein band 4.1 like 5
chr7_+_57069417 2.99 ENSMUST00000085240.11
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr9_+_32135540 2.84 ENSMUST00000168954.9
Rho GTPase activating protein 32
chr2_+_91090167 2.82 ENSMUST00000138470.2
protein kinase C and casein kinase substrate in neurons 3
chr4_-_139974062 2.81 ENSMUST00000039331.9
immunoglobulin superfamily, member 21
chr19_+_29923182 2.79 ENSMUST00000025724.9
interleukin 33
chr4_-_49593875 2.79 ENSMUST00000151542.2
post-GPI attachment to proteins GalNAc transferase 4
chr5_-_86780277 2.78 ENSMUST00000116553.9
transmembrane protease, serine 11f
chr19_-_47680528 2.75 ENSMUST00000026045.14
ENSMUST00000086923.6
collagen, type XVII, alpha 1
chr2_+_14393245 2.71 ENSMUST00000133258.2
solute carrier family 39 (zinc transporter), member 12
chr1_-_160405464 2.71 ENSMUST00000238289.2
G protein-coupled receptor 52
chrX_-_42256694 2.65 ENSMUST00000115058.8
ENSMUST00000115059.8
teneurin transmembrane protein 1
chr11_+_70350725 2.61 ENSMUST00000147289.2
zinc finger, MYND-type containing 15
chr7_+_43418404 2.60 ENSMUST00000014063.6
kallikrein related-peptidase 12
chr6_-_138398376 2.57 ENSMUST00000163065.8
LIM domain only 3
chr3_-_10366229 2.54 ENSMUST00000119761.2
ENSMUST00000029043.13
fatty acid binding protein 12
chr4_-_155095441 2.51 ENSMUST00000105631.9
ENSMUST00000139976.9
ENSMUST00000145662.9
phospholipase C, eta 2
chr10_+_69761314 2.49 ENSMUST00000182692.8
ENSMUST00000092433.12
ankyrin 3, epithelial
chr6_+_115111872 2.36 ENSMUST00000009538.12
ENSMUST00000203450.2
synapsin II
chr3_-_33039225 2.23 ENSMUST00000108221.2
peroxisomal biogenesis factor 5-like
chr14_+_68321302 2.23 ENSMUST00000022639.8
neurofilament, light polypeptide
chr10_+_69761630 2.21 ENSMUST00000182029.8
ankyrin 3, epithelial
chr1_-_119576632 2.18 ENSMUST00000163147.8
ENSMUST00000052404.13
ENSMUST00000191046.7
erythrocyte membrane protein band 4.1 like 5
chr19_+_46120327 2.18 ENSMUST00000043739.6
ENSMUST00000237098.2
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3
chr3_-_123484499 2.14 ENSMUST00000154668.8
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr15_-_101801351 2.10 ENSMUST00000100179.2
keratin 76
chr10_+_59239466 2.09 ENSMUST00000009790.14
phospholipase A2, group XIIB
chr19_+_38252984 2.07 ENSMUST00000198518.5
ENSMUST00000199812.5
leucine-rich repeat LGI family, member 1
chr9_+_32135781 2.07 ENSMUST00000183121.2
Rho GTPase activating protein 32
chr2_-_9888804 2.05 ENSMUST00000114915.3
RIKEN cDNA 9230102O04 gene
chr10_+_128061699 2.04 ENSMUST00000026455.8
major intrinsic protein of lens fiber
chr16_-_17732923 2.04 ENSMUST00000012279.6
ENSMUST00000232493.2
goosecoid homebox 2
chr8_-_96615138 2.04 ENSMUST00000034097.8
glutamatic-oxaloacetic transaminase 2, mitochondrial
chr17_-_57366795 1.99 ENSMUST00000040280.14
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr15_+_18819033 1.97 ENSMUST00000166873.9
cadherin 10
chr2_-_23939401 1.97 ENSMUST00000051416.12
histamine N-methyltransferase
chr5_+_87148697 1.96 ENSMUST00000031186.9
UDP glucuronosyltransferase 2 family, polypeptide B35
chr7_+_24206431 1.95 ENSMUST00000176880.2
zinc finger protein 428
chr18_+_61058684 1.94 ENSMUST00000102888.10
ENSMUST00000025519.11
calcium/calmodulin-dependent protein kinase II alpha
chr3_+_136376440 1.91 ENSMUST00000056758.9
protein phosphatase 3, catalytic subunit, alpha isoform
chr3_+_94217396 1.89 ENSMUST00000049822.10
thioesterase superfamily member 4
chr12_+_36042899 1.88 ENSMUST00000020898.12
anterior gradient 2
chr4_-_116024788 1.85 ENSMUST00000030465.10
ENSMUST00000143426.2
tetraspanin 1
chr7_+_30252687 1.83 ENSMUST00000044048.8
heat shock protein, alpha-crystallin-related, B6
chr9_+_107217786 1.82 ENSMUST00000042581.4
RIKEN cDNA 6430571L13 gene
chr7_-_109092834 1.81 ENSMUST00000106739.8
tripartite motif-containing 66
chr18_-_60724855 1.81 ENSMUST00000056533.9
myozenin 3
chr10_+_80165787 1.80 ENSMUST00000105358.8
ENSMUST00000105357.2
ENSMUST00000105354.8
ENSMUST00000105355.8
receptor accessory protein 6
chr7_+_30399208 1.79 ENSMUST00000013227.8
RIKEN cDNA 2200002J24 gene
chr6_-_136150491 1.77 ENSMUST00000111905.8
ENSMUST00000152012.8
ENSMUST00000143943.8
ENSMUST00000125905.2
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr10_-_107330580 1.76 ENSMUST00000044210.5
myogenic factor 6
chr11_+_70350963 1.76 ENSMUST00000126105.2
zinc finger, MYND-type containing 15
chr1_+_167426019 1.75 ENSMUST00000111386.8
ENSMUST00000111384.8
retinoid X receptor gamma
chr13_-_116446166 1.74 ENSMUST00000036060.13
ISL1 transcription factor, LIM/homeodomain
chr6_+_115111860 1.73 ENSMUST00000169345.4
synapsin II
chr7_-_4527228 1.72 ENSMUST00000154913.2
troponin I, cardiac 3
chr18_+_73996743 1.72 ENSMUST00000134847.2
maestro
chr10_+_85763545 1.71 ENSMUST00000170396.3
achaete-scute family bHLH transcription factor 4
chr6_-_35285045 1.70 ENSMUST00000031868.5
solute carrier family 13 (sodium/sulfate symporters), member 4
chr1_-_110905082 1.69 ENSMUST00000094626.5
cadherin 19, type 2
chr1_+_66360865 1.68 ENSMUST00000114013.8
microtubule-associated protein 2
chr15_+_4404965 1.67 ENSMUST00000061925.5
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr6_-_142268692 1.66 ENSMUST00000081380.10
solute carrier organic anion transporter family, member 1a5
chr6_-_122317156 1.65 ENSMUST00000159384.8
polyhomeotic 1
chr1_+_99700490 1.64 ENSMUST00000086738.10
contactin associated protein-like 5B
chr6_+_104469751 1.62 ENSMUST00000161446.2
ENSMUST00000161070.8
ENSMUST00000089215.12
contactin 6
chr1_-_173195236 1.62 ENSMUST00000005470.5
ENSMUST00000111220.8
cell adhesion molecule 3
chrX_+_55825033 1.61 ENSMUST00000114772.9
ENSMUST00000114768.10
ENSMUST00000155882.8
four and a half LIM domains 1
chr14_-_28691423 1.58 ENSMUST00000225985.2
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr11_+_67586140 1.55 ENSMUST00000021290.2
recoverin
chr1_-_136158027 1.54 ENSMUST00000150163.8
ENSMUST00000144464.7
innate immunity activator
chr17_-_85397627 1.54 ENSMUST00000072406.5
ENSMUST00000171795.9
ENSMUST00000234676.2
prolyl endopeptidase-like
chr7_-_4517559 1.54 ENSMUST00000163538.8
troponin T1, skeletal, slow
chr3_+_136375839 1.52 ENSMUST00000070198.14
protein phosphatase 3, catalytic subunit, alpha isoform
chr17_+_58076565 1.50 ENSMUST00000076038.7
contactin associated protein-like 5C
chr6_-_29380423 1.48 ENSMUST00000147483.3
opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)
chr12_-_109019507 1.47 ENSMUST00000185745.2
ENSMUST00000239108.2
brain-enriched guanylate kinase-associated
chr10_+_80165961 1.47 ENSMUST00000186864.7
ENSMUST00000040081.7
receptor accessory protein 6
chr8_-_106863423 1.46 ENSMUST00000146940.2
epithelial splicing regulatory protein 2
chr17_-_35351026 1.46 ENSMUST00000025249.7
apolipoprotein M
chr2_+_22958956 1.45 ENSMUST00000226571.2
ENSMUST00000114529.10
ENSMUST00000114526.9
ENSMUST00000228050.2
acyl-Coenzyme A binding domain containing 5
chr2_+_22958179 1.44 ENSMUST00000227663.2
ENSMUST00000028121.15
ENSMUST00000227809.2
ENSMUST00000144088.2
acyl-Coenzyme A binding domain containing 5
chr6_-_83504471 1.44 ENSMUST00000141904.8
actin, gamma 2, smooth muscle, enteric
chrX_+_55824797 1.44 ENSMUST00000114773.10
four and a half LIM domains 1
chr4_-_137493785 1.42 ENSMUST00000139951.8
alkaline phosphatase, liver/bone/kidney
chr14_-_31362835 1.39 ENSMUST00000167066.8
ENSMUST00000127204.9
2-hydroxyacyl-CoA lyase 1
chr14_-_70666513 1.39 ENSMUST00000226426.2
ENSMUST00000048129.6
piwi-like RNA-mediated gene silencing 2
chr14_-_64654397 1.38 ENSMUST00000210428.2
methionine sulfoxide reductase A
chr8_-_106863521 1.37 ENSMUST00000115979.9
epithelial splicing regulatory protein 2
chr2_-_101459274 1.36 ENSMUST00000099682.9
intraflagellar transport associated protein
chr1_+_167425953 1.35 ENSMUST00000015987.10
retinoid X receptor gamma
chr7_-_101517874 1.35 ENSMUST00000150184.2
folate receptor 1 (adult)
chr10_+_18283405 1.35 ENSMUST00000037341.14
NHS-like 1
chr17_-_23805187 1.32 ENSMUST00000227952.2
ENSMUST00000115516.11
zinc finger protein 13
chr19_-_8196196 1.31 ENSMUST00000113298.9
solute carrier family 22. member 29
chr6_-_29380467 1.30 ENSMUST00000080428.13
opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)
chr6_+_58810674 1.30 ENSMUST00000041401.11
hect domain and RLD 3
chr11_-_69127848 1.29 ENSMUST00000021259.9
ENSMUST00000108665.8
ENSMUST00000108664.2
guanylate cyclase 2e
chr7_-_106423873 1.26 ENSMUST00000208895.3
olfactory receptor 702
chr7_+_143792455 1.26 ENSMUST00000239495.2
SH3 and multiple ankyrin repeat domains 2
chr1_-_13730732 1.26 ENSMUST00000027071.7
lactamase, beta 2
chr2_-_101459303 1.25 ENSMUST00000111231.10
intraflagellar transport associated protein
chr1_+_66361252 1.24 ENSMUST00000123647.8
microtubule-associated protein 2
chr7_-_101518217 1.23 ENSMUST00000123321.8
folate receptor 1 (adult)
chr6_+_121277186 1.23 ENSMUST00000064580.14
solute carrier family 6 (neurotransmitter transporter, GABA), member 13
chr7_+_107702486 1.20 ENSMUST00000104917.4
olfactory receptor 483
chr7_-_4517608 1.18 ENSMUST00000166959.8
troponin T1, skeletal, slow
chr17_+_12803019 1.17 ENSMUST00000046959.9
ENSMUST00000233066.2
solute carrier family 22 (organic cation transporter), member 2
chr6_-_93890659 1.16 ENSMUST00000093769.8
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr3_-_26207456 1.16 ENSMUST00000191835.2
neuroligin 1
chr12_+_119356318 1.16 ENSMUST00000221866.2
metastasis associated in colon cancer 1
chr5_-_66161621 1.16 ENSMUST00000201351.4
RIKEN cDNA 9130230L23 gene
chr6_-_93890520 1.15 ENSMUST00000203688.3
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr1_+_74830675 1.15 ENSMUST00000006718.15
wingless-type MMTV integration site family, member 10A
chr18_-_3299452 1.12 ENSMUST00000126578.8
cAMP responsive element modulator
chr16_+_8288627 1.11 ENSMUST00000046470.16
ENSMUST00000150790.2
ENSMUST00000142899.2
methyltransferase like 22
chr18_+_61058716 1.09 ENSMUST00000115297.8
calcium/calmodulin-dependent protein kinase II alpha
chr12_+_78243846 1.08 ENSMUST00000188791.2
predicted gene 6657
chr10_+_90412827 1.08 ENSMUST00000182550.8
ENSMUST00000099364.12
ankyrin repeat and sterile alpha motif domain containing 1B
chr10_+_21869776 1.07 ENSMUST00000092673.11
serum/glucocorticoid regulated kinase 1
chr3_-_84178089 1.07 ENSMUST00000054990.11
tripartite motif-containing 2
chr3_+_135053762 1.07 ENSMUST00000159658.8
ENSMUST00000078568.12
solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1
chr2_-_121287174 1.05 ENSMUST00000110613.9
ENSMUST00000056312.10
serine incorporator 4
chr19_-_12897671 1.05 ENSMUST00000054737.3
olfactory receptor 1448
chr6_+_142359099 1.04 ENSMUST00000126521.9
ENSMUST00000211094.2
spexin hormone
chr2_+_136733421 1.03 ENSMUST00000141463.8
SLX4 interacting protein
chr3_-_33136153 1.03 ENSMUST00000108225.10
peroxisomal biogenesis factor 5-like
chr7_+_88079534 1.02 ENSMUST00000208478.2
RAB38, member RAS oncogene family
chr14_+_28740162 1.02 ENSMUST00000055662.4
leucine-rich repeats and transmembrane domains 1
chr11_-_51647290 1.02 ENSMUST00000109097.9
Sec24 related gene family, member A (S. cerevisiae)
chr8_-_22422724 1.01 ENSMUST00000062586.3
defensin beta 15
chr11_-_59078565 0.98 ENSMUST00000170895.3
guanylate kinase 1
chr2_+_38231080 0.97 ENSMUST00000133661.8
LIM homeobox protein 2
chr4_+_136349924 0.97 ENSMUST00000178843.3
lactamase, beta-like 1
chr18_-_20192535 0.97 ENSMUST00000075214.9
ENSMUST00000039247.11
desmocollin 2
chr4_+_84802592 0.96 ENSMUST00000102819.10
centlein, centrosomal protein
chrX_-_135642025 0.96 ENSMUST00000155207.8
ENSMUST00000080411.13
ENSMUST00000169418.8
mortality factor 4 like 2
chr13_+_96884780 0.94 ENSMUST00000208758.2
ankyrin repeat domain 31
chr2_+_69500444 0.94 ENSMUST00000100050.4
kelch-like 41
chr11_-_70350783 0.92 ENSMUST00000019064.9
chemokine (C-X-C motif) ligand 16
chrX_-_166907286 0.92 ENSMUST00000239138.2
FERM and PDZ domain containing 4
chr9_-_100368841 0.91 ENSMUST00000098458.4
interleukin 20 receptor beta
chr1_-_171050004 0.91 ENSMUST00000147246.2
ENSMUST00000111326.8
ENSMUST00000138184.8
translocase of outer mitochondrial membrane 40-like
chr15_-_79138929 0.91 ENSMUST00000039752.4
solute carrier family 16 (monocarboxylic acid transporters), member 8
chr4_-_139560831 0.91 ENSMUST00000030508.14
paired box 7
chr2_-_113047313 0.90 ENSMUST00000208135.2
ENSMUST00000134358.9
ryanodine receptor 3
chr11_+_4587733 0.90 ENSMUST00000070257.14
ENSMUST00000109930.3
activating signal cointegrator 1 complex subunit 2
chr1_+_133249613 0.90 ENSMUST00000007433.5
KiSS-1 metastasis-suppressor
chr4_-_43823866 0.89 ENSMUST00000215406.2
ENSMUST00000079234.6
ENSMUST00000214843.2
olfactory receptor 156
chr18_-_3299536 0.88 ENSMUST00000129435.8
ENSMUST00000122958.8
cAMP responsive element modulator
chr10_-_78143384 0.87 ENSMUST00000150828.2
ENSMUST00000239481.2
1-acylglycerol-3-phosphate O-acyltransferase 3

chr11_-_43792013 0.87 ENSMUST00000067258.9
ENSMUST00000139906.2
adrenergic receptor, alpha 1b
chr6_-_23650205 0.86 ENSMUST00000115354.2
ring finger protein 133
chr6_+_42873387 0.85 ENSMUST00000058668.4
olfactory receptor 448
chr4_+_101407608 0.83 ENSMUST00000094953.11
ENSMUST00000106933.2
DnaJ heat shock protein family (Hsp40) member C6
chr6_+_136931519 0.82 ENSMUST00000137768.2
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr9_-_54408780 0.81 ENSMUST00000118600.8
ENSMUST00000118163.8
Dmx-like 2
chr14_+_65504151 0.81 ENSMUST00000169656.3
ENSMUST00000226005.2
F-box protein 16
chr17_-_29768531 0.80 ENSMUST00000168339.3
ENSMUST00000114683.10
ENSMUST00000234620.2
transmembrane protein 217
chr1_-_171050077 0.80 ENSMUST00000005817.9
translocase of outer mitochondrial membrane 40-like
chrX_+_92718695 0.79 ENSMUST00000045898.4
phosphate cytidylyltransferase 1, choline, beta isoform
chr11_+_29668563 0.78 ENSMUST00000060992.6
reticulon 4
chr1_-_86317066 0.77 ENSMUST00000212058.2
neuromedin U receptor 1
chr17_-_29768586 0.76 ENSMUST00000234305.2
ENSMUST00000234648.2
ENSMUST00000234979.2
predicted gene, 17657
transmembrane protein 217
chr17_+_35188888 0.76 ENSMUST00000173680.2
predicted gene 20481
chr2_+_80447389 0.76 ENSMUST00000028384.5
dual specificity phosphatase 19
chr2_-_113047397 0.76 ENSMUST00000080673.13
ENSMUST00000208151.2
ENSMUST00000208290.2
ryanodine receptor 3
chr2_+_124994425 0.75 ENSMUST00000110494.9
ENSMUST00000110495.3
ENSMUST00000028630.9
solute carrier family 12, member 1
chr16_-_56748424 0.73 ENSMUST00000210579.2
leukemia NUP98 fusion partner 1
chr5_-_87240405 0.73 ENSMUST00000132667.2
ENSMUST00000145617.8
ENSMUST00000094649.11
UDP glucuronosyltransferase 2 family, polypeptide B36
chr3_+_89427458 0.72 ENSMUST00000000811.8
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr4_-_35845204 0.72 ENSMUST00000164772.8
ENSMUST00000065173.9
leucine rich repeat and Ig domain containing 2
chr17_-_28584117 0.70 ENSMUST00000233420.2
tubby like protein 1
chr4_-_109333866 0.70 ENSMUST00000030284.10
ring finger protein 11
chr2_-_38816229 0.68 ENSMUST00000076275.11
ENSMUST00000142130.2
nuclear receptor subfamily 6, group A, member 1
chr6_-_89822597 0.68 ENSMUST00000089419.3
vomeronasal 1 receptor 42
chr17_-_59298338 0.67 ENSMUST00000025064.14
PDZ and pleckstrin homology domains 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.4 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
1.4 5.7 GO:0003360 brainstem development(GO:0003360)
1.1 3.4 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
1.0 3.8 GO:0090472 dibasic protein processing(GO:0090472)
0.9 11.8 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.9 1.7 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.8 6.5 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.7 2.2 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.7 2.0 GO:0006533 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.6 1.9 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.6 5.1 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.5 4.0 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.5 2.0 GO:0097274 urea homeostasis(GO:0097274)
0.5 3.4 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.5 1.5 GO:0034443 negative regulation of lipoprotein oxidation(GO:0034443)
0.5 3.2 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.5 2.7 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.4 6.4 GO:0015747 urate transport(GO:0015747)
0.4 2.8 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.4 2.0 GO:0001692 histamine metabolic process(GO:0001692)
0.4 1.2 GO:0048789 cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942)
0.4 1.1 GO:0021627 olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
0.4 1.8 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.3 1.4 GO:0000239 pachytene(GO:0000239)
0.3 6.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.3 1.3 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.3 1.0 GO:0046710 GDP metabolic process(GO:0046710)
0.3 2.8 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.3 0.9 GO:0001807 regulation of type IV hypersensitivity(GO:0001807)
0.3 0.9 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.3 0.9 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982)
0.3 1.7 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.3 2.6 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.3 2.9 GO:0030242 pexophagy(GO:0030242)
0.2 2.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 3.0 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.2 1.4 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.2 1.8 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.2 3.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.2 0.7 GO:2000595 optic nerve formation(GO:0021634) optic chiasma development(GO:0061360) regulation of optic nerve formation(GO:2000595) positive regulation of optic nerve formation(GO:2000597)
0.2 0.6 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.2 2.2 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 0.5 GO:1903722 regulation of centriole elongation(GO:1903722)
0.2 0.5 GO:2001178 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.2 0.6 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.7 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.1 1.2 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 3.3 GO:0048733 sebaceous gland development(GO:0048733)
0.1 1.0 GO:0060155 platelet dense granule organization(GO:0060155) phagosome acidification(GO:0090383) melanosome assembly(GO:1903232)
0.1 0.8 GO:0072318 clathrin coat disassembly(GO:0072318)
0.1 1.3 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.4 GO:0006212 uracil catabolic process(GO:0006212) uracil metabolic process(GO:0019860)
0.1 3.0 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.6 GO:0061643 chemoattraction of axon(GO:0061642) chemorepulsion of axon(GO:0061643)
0.1 1.8 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.6 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 1.0 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 2.8 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.9 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 1.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 1.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 0.6 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.1 0.5 GO:1903566 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.1 0.8 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 1.0 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.2 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416)
0.1 0.3 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 3.1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 1.8 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.1 3.8 GO:0010107 potassium ion import(GO:0010107)
0.1 3.7 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 1.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 1.1 GO:0006883 cellular sodium ion homeostasis(GO:0006883) glucocorticoid mediated signaling pathway(GO:0043402)
0.1 1.7 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.1 3.6 GO:0007340 acrosome reaction(GO:0007340)
0.1 1.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.5 GO:1904306 positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.1 1.2 GO:0015697 quaternary ammonium group transport(GO:0015697) histamine transport(GO:0051608)
0.1 0.6 GO:0070836 caveola assembly(GO:0070836)
0.1 2.8 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.1 0.8 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.9 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 2.1 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 0.9 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.1 1.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 4.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.9 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902108)
0.0 0.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 1.8 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 6.2 GO:0032091 negative regulation of protein binding(GO:0032091)
0.0 0.9 GO:0008272 sulfate transport(GO:0008272)
0.0 0.8 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.9 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 1.5 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 1.3 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.9 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.1 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0 0.6 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.4 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0 1.0 GO:2000678 negative regulation of transcription regulatory region DNA binding(GO:2000678)
0.0 2.6 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.4 GO:1902224 ketone body metabolic process(GO:1902224)
0.0 0.8 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 2.0 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 1.4 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.6 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.5 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.4 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.0 0.8 GO:1901186 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 2.9 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 0.2 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 1.6 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 2.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 3.8 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 1.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 6.6 GO:0016485 protein processing(GO:0016485)
0.0 0.2 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 1.6 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 1.1 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.3 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.6 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 2.1 GO:0050806 positive regulation of synaptic transmission(GO:0050806)
0.0 2.8 GO:0007286 spermatid development(GO:0007286)
0.0 0.2 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 0.2 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.1 GO:0043585 nose morphogenesis(GO:0043585) alveolar primary septum development(GO:0061143)
0.0 0.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.4 GO:0031424 keratinization(GO:0031424)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.7 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
1.1 3.3 GO:0044317 rod spherule(GO:0044317)
0.8 6.5 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.8 3.0 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
0.6 2.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.5 2.0 GO:0046691 intracellular canaliculus(GO:0046691)
0.4 3.1 GO:0005955 calcineurin complex(GO:0005955)
0.4 11.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.3 2.9 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.3 4.0 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.3 1.5 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.3 1.4 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.3 0.8 GO:0043291 RAVE complex(GO:0043291)
0.2 1.7 GO:1990584 cardiac Troponin complex(GO:1990584)
0.2 2.7 GO:0005861 troponin complex(GO:0005861)
0.2 3.8 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.2 7.9 GO:0045095 keratin filament(GO:0045095)
0.2 1.4 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 1.7 GO:0030314 junctional membrane complex(GO:0030314)
0.1 1.7 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 11.3 GO:0005882 intermediate filament(GO:0005882)
0.1 2.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 2.8 GO:0030056 hemidesmosome(GO:0030056)
0.1 1.2 GO:0001739 sex chromatin(GO:0001739)
0.1 2.8 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 2.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 1.4 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.1 3.4 GO:0030673 axolemma(GO:0030673)
0.1 1.8 GO:0010369 chromocenter(GO:0010369)
0.1 4.1 GO:0031201 SNARE complex(GO:0031201)
0.1 0.3 GO:0035841 new growing cell tip(GO:0035841)
0.1 1.0 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.0 GO:0031045 dense core granule(GO:0031045)
0.0 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.9 GO:0031143 pseudopodium(GO:0031143)
0.0 5.2 GO:0030315 T-tubule(GO:0030315)
0.0 1.4 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 2.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.1 GO:0043034 costamere(GO:0043034)
0.0 6.7 GO:0043204 perikaryon(GO:0043204)
0.0 1.0 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0098830 presynaptic endosome(GO:0098830)
0.0 2.8 GO:0043195 terminal bouton(GO:0043195)
0.0 0.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.1 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.8 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 3.0 GO:0032587 ruffle membrane(GO:0032587)
0.0 6.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.0 8.8 GO:0030141 secretory granule(GO:0030141)
0.0 2.7 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.2 GO:0044754 autolysosome(GO:0044754)
0.0 0.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 4.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 3.2 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.6 GO:0030018 Z disc(GO:0030018)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 6.5 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
1.0 5.1 GO:0070012 oligopeptidase activity(GO:0070012)
0.9 6.2 GO:0004111 creatine kinase activity(GO:0004111)
0.7 2.0 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.7 2.7 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.6 5.7 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.6 3.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.6 3.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.5 3.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.4 4.5 GO:0031014 troponin T binding(GO:0031014)
0.4 1.7 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.4 1.2 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) norepinephrine transmembrane transporter activity(GO:0005333) acetate ester transmembrane transporter activity(GO:1901375)
0.4 6.4 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.4 1.8 GO:0051373 FATZ binding(GO:0051373)
0.3 1.4 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.3 1.0 GO:0036461 BLOC-2 complex binding(GO:0036461)
0.3 2.9 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.3 2.8 GO:0004568 chitinase activity(GO:0004568)
0.3 3.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.3 2.1 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.3 0.9 GO:0042015 interleukin-20 binding(GO:0042015)
0.3 3.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.3 3.0 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.3 1.4 GO:0034584 piRNA binding(GO:0034584)
0.3 0.8 GO:0001607 neuromedin U receptor activity(GO:0001607)
0.3 0.8 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 1.8 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529)
0.2 2.6 GO:0051870 methotrexate binding(GO:0051870)
0.2 5.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 0.9 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.2 3.8 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 1.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 1.4 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.2 0.8 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 2.5 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.2 3.0 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 0.7 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.2 0.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 2.2 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 2.0 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.2 1.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2 3.0 GO:0002162 dystroglycan binding(GO:0002162)
0.2 1.7 GO:0015288 porin activity(GO:0015288)
0.2 6.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.4 GO:0002061 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061)
0.1 1.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 4.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.4 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.1 0.6 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 5.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.4 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 17.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 4.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 1.9 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 2.9 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 1.5 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 0.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.7 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 4.0 GO:0051393 alpha-actinin binding(GO:0051393)
0.1 2.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 17.3 GO:0008236 serine-type peptidase activity(GO:0008236)
0.1 1.1 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.1 0.4 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 2.1 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 1.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.0 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 1.1 GO:0008276 protein methyltransferase activity(GO:0008276)
0.1 0.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 4.4 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.7 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.9 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 4.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.9 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.6 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.2 GO:0002046 opsin binding(GO:0002046)
0.0 1.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.7 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.6 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.9 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.7 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 1.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 4.4 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 11.5 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 2.0 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 1.1 GO:0017022 myosin binding(GO:0017022)
0.0 0.4 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.7 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 1.5 GO:0016209 antioxidant activity(GO:0016209)
0.0 5.2 GO:0005549 odorant binding(GO:0005549)
0.0 1.6 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.7 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.8 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 4.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 5.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 5.9 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 2.9 PID LKB1 PATHWAY LKB1 signaling events
0.0 3.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 4.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.8 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.2 PID TXA2PATHWAY Thromboxane A2 receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 9.0 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.4 6.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.3 3.3 REACTOME OPSINS Genes involved in Opsins
0.2 4.1 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.2 11.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 7.0 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.2 3.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.9 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 3.0 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 5.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 1.0 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 2.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 2.2 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.1 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.6 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 1.4 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 2.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 3.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.8 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.9 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.6 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 3.3 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)