ISMARA results: Pitx2

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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Pitx2_Otx2

Z-value: 1.52

Motif logo

Transcription factors associated with Pitx2_Otx2

Gene Symbol	Gene ID	Gene Info
Pitx2 Ensembl NCBI MGI UniProt	ENSMUSG00000028023.17	Pitx2
Otx2 Ensembl NCBI MGI UniProt	ENSMUSG00000021848.17	Otx2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Otx2	mm39_v1_chr14_-_48902555_48902572	-0.31	7.7e-03	Click!
Pitx2	mm39_v1_chr3_+_128993527_128993563	0.03	8.3e-01	Click!

Activity profile of Pitx2_Otx2 motif

Sorted Z-values of Pitx2_Otx2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Pitx2_Otx2

View svg image
View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr17_+_36172210 Show fit	12.81	ENSMUST00000074259.15 ENSMUST00000174873.2	Nrm Ensembl NCBI MGI UniProt Show fit	nurim (nuclear envelope membrane protein)
chr9_+_72345267 Show fit	12.29	ENSMUST00000183809.8	Mns1 Ensembl NCBI MGI UniProt Show fit	meiosis-specific nuclear structural protein 1
chr9_+_110248815 Show fit	11.92	ENSMUST00000035061.9	Ngp Ensembl NCBI MGI UniProt Show fit	neutrophilic granule protein
chr11_-_97886997 Show fit	11.92	ENSMUST00000042971.16	Arl5c Ensembl NCBI MGI UniProt Show fit	ADP-ribosylation factor-like 5C
chr11_-_6470918 Show fit	11.28	ENSMUST00000003459.4	Myo1g Ensembl NCBI MGI UniProt Show fit	myosin IG
chr14_+_52348396 Show fit	10.34	ENSMUST00000111600.11	Rpgrip1 Ensembl NCBI MGI UniProt Show fit	retinitis pigmentosa GTPase regulator interacting protein 1
chr4_-_117039809 Show fit	10.26	ENSMUST00000065896.9	Kif2c Ensembl NCBI MGI UniProt Show fit	kinesin family member 2C
chr13_-_22193900 Show fit	9.96	ENSMUST00000006341.4	Prss16 Ensembl NCBI MGI UniProt Show fit	protease, serine 16 (thymus)
chr11_+_117673107 Show fit	8.53	ENSMUST00000050874.14 ENSMUST00000106334.9	Tmc8 Ensembl NCBI MGI UniProt Show fit	transmembrane channel-like gene family 8
chr5_-_76478935 Show fit	8.46	ENSMUST00000122213.8 ENSMUST00000031145.7	Pdcl2 Ensembl NCBI MGI UniProt Show fit	phosducin-like 2
chr7_+_46510627 Show fit	8.45	ENSMUST00000014545.11	Ldhc Ensembl NCBI MGI UniProt Show fit	lactate dehydrogenase C
chr17_-_47074617 Show fit	8.35	ENSMUST00000041012.9	Ptcra Ensembl NCBI MGI UniProt Show fit	pre T cell antigen receptor alpha
chr4_-_43483696 Show fit	8.00	ENSMUST00000030180.7	Sit1 Ensembl NCBI MGI UniProt Show fit	suppression inducing transmembrane adaptor 1
chr7_+_28140450 Show fit	7.99	ENSMUST00000135686.2	Gmfg Ensembl NCBI MGI UniProt Show fit	glia maturation factor, gamma
chr3_+_98067940 Show fit	7.90	ENSMUST00000198363.2 ENSMUST00000050342.5	Adam30 Ensembl NCBI MGI UniProt Show fit	a disintegrin and metallopeptidase domain 30
chr6_+_41128636 Show fit	7.74	ENSMUST00000103274.4	Trbv16 Ensembl NCBI MGI UniProt Show fit	T cell receptor beta, variable 16
chr9_-_70328816 Show fit	7.74	ENSMUST00000034742.8	Ccnb2 Ensembl NCBI MGI UniProt Show fit	cyclin B2
chr17_+_36172235 Show fit	7.73	ENSMUST00000172931.2	Nrm Ensembl NCBI MGI UniProt Show fit	nurim (nuclear envelope membrane protein)
chr6_-_88875646 Show fit	7.69	ENSMUST00000058011.8	Mcm2 Ensembl NCBI MGI UniProt Show fit	minichromosome maintenance complex component 2
chr7_+_46510677 Show fit	7.59	ENSMUST00000211784.2 ENSMUST00000210585.2 ENSMUST00000148565.8	Ldhc Ensembl NCBI MGI UniProt Show fit	lactate dehydrogenase C
chr2_+_91376650 Show fit	7.45	ENSMUST00000099716.11 ENSMUST00000046769.16 ENSMUST00000111337.3	Ckap5 Ensembl NCBI MGI UniProt Show fit	cytoskeleton associated protein 5
chr7_+_28140352 Show fit	7.39	ENSMUST00000078845.13	Gmfg Ensembl NCBI MGI UniProt Show fit	glia maturation factor, gamma
chr5_+_66018555 Show fit	7.23	ENSMUST00000031106.8	Rhoh Ensembl NCBI MGI UniProt Show fit	ras homolog family member H
chr19_+_4204605 Show fit	7.02	ENSMUST00000061086.9	Ptprcap Ensembl NCBI MGI UniProt Show fit	protein tyrosine phosphatase, receptor type, C polypeptide-associated protein
chr17_-_6923299 Show fit	6.95	ENSMUST00000179554.3	Dynlt1f Ensembl NCBI MGI UniProt Show fit	dynein light chain Tctex-type 1F
chr7_+_44358144 Show fit	6.94	ENSMUST00000085422.4	Izumo2 Ensembl NCBI MGI UniProt Show fit	IZUMO family member 2
chr7_+_16515265 Show fit	6.81	ENSMUST00000108496.9	Slc1a5 Ensembl NCBI MGI UniProt Show fit	solute carrier family 1 (neutral amino acid transporter), member 5
chr5_+_110478558 Show fit	6.66	ENSMUST00000112481.2	Pole Ensembl NCBI MGI UniProt Show fit	polymerase (DNA directed), epsilon
chr5_-_72910106 Show fit	6.60	ENSMUST00000197313.5 ENSMUST00000198464.3 ENSMUST00000113604.10	Txk Ensembl NCBI MGI UniProt Show fit	TXK tyrosine kinase
chr17_+_30845909 Show fit	6.58	ENSMUST00000236140.2 ENSMUST00000236118.2 ENSMUST00000235390.2	Dnah8 Ensembl NCBI MGI UniProt Show fit	dynein, axonemal, heavy chain 8
chr17_+_6697511 Show fit	6.58	ENSMUST00000179569.3	Dynlt1b Ensembl NCBI MGI UniProt Show fit	dynein light chain Tctex-type 1B
chr4_+_116030561 Show fit	6.49	ENSMUST00000106492.3 ENSMUST00000216692.2	1700042G07Rik Ensembl NCBI MGI UniProt Show fit Gm49337 Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 1700042G07 gene predicted gene, 49337
chr11_-_69786324 Show fit	6.45	ENSMUST00000001631.7	Acap1 Ensembl NCBI MGI UniProt Show fit	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr6_-_124865155 Show fit	6.45	ENSMUST00000024044.7	Cd4 Ensembl NCBI MGI UniProt Show fit	CD4 antigen
chr15_-_82128888 Show fit	6.39	ENSMUST00000089155.6 ENSMUST00000089157.11	Cenpm Ensembl NCBI MGI UniProt Show fit	centromere protein M
chr14_+_66043515 Show fit	6.27	ENSMUST00000139644.2	Pbk Ensembl NCBI MGI UniProt Show fit	PDZ binding kinase
chr8_-_106706035 Show fit	6.25	ENSMUST00000034371.9	Dpep3 Ensembl NCBI MGI UniProt Show fit	dipeptidase 3
chr14_-_47655621 Show fit	6.16	ENSMUST00000180299.8	Dlgap5 Ensembl NCBI MGI UniProt Show fit	DLG associated protein 5
chr4_-_58009118 Show fit	6.13	ENSMUST00000102897.11 ENSMUST00000239406.2	Txndc8 Ensembl NCBI MGI UniProt Show fit	thioredoxin domain containing 8
chr17_+_29712008 Show fit	6.08	ENSMUST00000234665.2	Pim1 Ensembl NCBI MGI UniProt Show fit	proviral integration site 1
chr3_-_36626101 Show fit	6.06	ENSMUST00000029270.10	Ccna2 Ensembl NCBI MGI UniProt Show fit	cyclin A2
chr6_+_41036271 Show fit	6.02	ENSMUST00000103265.5	Trbv4 Ensembl NCBI MGI UniProt Show fit	T cell receptor beta, variable 10
chr15_-_99268311 Show fit	6.01	ENSMUST00000081224.14 ENSMUST00000120633.2 ENSMUST00000088233.13	Fmnl3 Ensembl NCBI MGI UniProt Show fit	formin-like 3
chr7_-_100164007 Show fit	6.00	ENSMUST00000207405.2	Dnajb13 Ensembl NCBI MGI UniProt Show fit	DnaJ heat shock protein family (Hsp40) member B13
chr2_+_101455079 Show fit	5.99	ENSMUST00000111227.2	Rag2 Ensembl NCBI MGI UniProt Show fit	recombination activating gene 2
chr7_+_43090206 Show fit	5.83	ENSMUST00000040227.3	Cldnd2 Ensembl NCBI MGI UniProt Show fit	claudin domain containing 2
chr4_-_117622747 Show fit	5.81	ENSMUST00000062747.6	Klf17 Ensembl NCBI MGI UniProt Show fit	Kruppel-like factor 17
chr4_-_149222057 Show fit	5.76	ENSMUST00000030813.10	Cenps Ensembl NCBI MGI UniProt Show fit	centromere protein S
chr15_-_103337982 Show fit	5.64	ENSMUST00000146736.8	Gtsf1 Ensembl NCBI MGI UniProt Show fit	gametocyte specific factor 1
chr17_-_29162794 Show fit	5.62	ENSMUST00000232977.2	Pxt1 Ensembl NCBI MGI UniProt Show fit	peroxisomal, testis specific 1
chrX_-_9335525 Show fit	5.60	ENSMUST00000015484.10	Cybb Ensembl NCBI MGI UniProt Show fit	cytochrome b-245, beta polypeptide
chr19_+_37364791 Show fit	5.60	ENSMUST00000012587.4	Kif11 Ensembl NCBI MGI UniProt Show fit	kinesin family member 11
chr9_+_103182352 Show fit	5.58	ENSMUST00000035164.10	Topbp1 Ensembl NCBI MGI UniProt Show fit	topoisomerase (DNA) II binding protein 1
chr12_-_28632514 Show fit	5.54	ENSMUST00000110917.2 ENSMUST00000020965.14	Allc Ensembl NCBI MGI UniProt Show fit	allantoicase
chr3_-_90603013 Show fit	5.51	ENSMUST00000069960.12 ENSMUST00000117167.2	S100a9 Ensembl NCBI MGI UniProt Show fit	S100 calcium binding protein A9 (calgranulin B)
chr4_+_137180565 Show fit	5.50	ENSMUST00000048893.4	1700013G24Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 1700013G24 gene
chr6_+_128864549 Show fit	5.46	ENSMUST00000032519.12 ENSMUST00000159866.8 ENSMUST00000162666.4 ENSMUST00000160867.3	Clec2i Ensembl NCBI MGI UniProt Show fit	C-type lectin domain family 2, member i
chr13_-_113237505 Show fit	5.45	ENSMUST00000224282.2 ENSMUST00000023897.7	Gzma Ensembl NCBI MGI UniProt Show fit	granzyme A
chr9_+_72345801 Show fit	5.44	ENSMUST00000184604.8 ENSMUST00000034746.10	Mns1 Ensembl NCBI MGI UniProt Show fit	meiosis-specific nuclear structural protein 1
chr5_+_136722995 Show fit	5.40	ENSMUST00000197186.2	Myl10 Ensembl NCBI MGI UniProt Show fit	myosin, light chain 10, regulatory
chr19_-_47907705 Show fit	5.40	ENSMUST00000095998.7	Itprip Ensembl NCBI MGI UniProt Show fit	inositol 1,4,5-triphosphate receptor interacting protein
chr2_+_101455022 Show fit	5.35	ENSMUST00000044031.4	Rag2 Ensembl NCBI MGI UniProt Show fit	recombination activating gene 2
chr2_-_32278245 Show fit	5.34	ENSMUST00000192241.2	Lcn2 Ensembl NCBI MGI UniProt Show fit	lipocalin 2
chr4_-_149221998 Show fit	5.34	ENSMUST00000176124.8 ENSMUST00000177408.2 ENSMUST00000105695.2	Cenps Ensembl NCBI MGI UniProt Show fit	centromere protein S
chr16_+_36004452 Show fit	5.25	ENSMUST00000114858.2	Cstdc4 Ensembl NCBI MGI UniProt Show fit	cystatin domain containing 4
chr10_+_4291193 Show fit	5.25	ENSMUST00000239220.2	Akap12 Ensembl NCBI MGI UniProt Show fit	A kinase (PRKA) anchor protein (gravin) 12
chr11_-_106889291 Show fit	5.21	ENSMUST00000124541.8	Kpna2 Ensembl NCBI MGI UniProt Show fit	karyopherin (importin) alpha 2
chr7_+_6998299 Show fit	5.20	ENSMUST00000208049.2 ENSMUST00000086248.7 ENSMUST00000208518.2 ENSMUST00000207711.2	Aurkc Ensembl NCBI MGI UniProt Show fit	aurora kinase C
chr1_-_28819331 Show fit	5.20	ENSMUST00000059937.5	Gm597 Ensembl NCBI MGI UniProt Show fit	predicted gene 597
chr10_-_60532250 Show fit	5.17	ENSMUST00000105464.9 ENSMUST00000105463.9 ENSMUST00000105461.10	Cdh23 Ensembl NCBI MGI UniProt Show fit	cadherin 23 (otocadherin)
chr11_-_54968901 Show fit	5.15	ENSMUST00000055040.13	Ccdc69 Ensembl NCBI MGI UniProt Show fit	coiled-coil domain containing 69
chr5_+_107977965 Show fit	5.04	ENSMUST00000072578.8	Ube2d2b Ensembl NCBI MGI UniProt Show fit	ubiquitin-conjugating enzyme E2D 2B
chr10_-_80374916 Show fit	5.03	ENSMUST00000219648.2	Atp8b3 Ensembl NCBI MGI UniProt Show fit	ATPase, class I, type 8B, member 3
chr6_+_41511248 Show fit	5.02	ENSMUST00000192366.2 ENSMUST00000103286.2	Trbj1-3 Ensembl NCBI MGI UniProt Show fit	T cell receptor beta joining 1-3
chr3_+_130906434 Show fit	4.99	ENSMUST00000098611.4	Lef1 Ensembl NCBI MGI UniProt Show fit	lymphoid enhancer binding factor 1
chr9_+_106377181 Show fit	4.99	ENSMUST00000085114.8	Iqcf1 Ensembl NCBI MGI UniProt Show fit	IQ motif containing F1
chr9_+_106391771 Show fit	4.92	ENSMUST00000085113.5	Iqcf5 Ensembl NCBI MGI UniProt Show fit	IQ motif containing F5
chr11_+_88861073 Show fit	4.89	ENSMUST00000107898.8	Coil Ensembl NCBI MGI UniProt Show fit	coilin
chr5_+_137777111 Show fit	4.84	ENSMUST00000126126.8 ENSMUST00000031739.6	Ppp1r35 Ensembl NCBI MGI UniProt Show fit	protein phosphatase 1, regulatory subunit 35
chr1_+_85503397 Show fit	4.83	ENSMUST00000178024.2	G530012D18Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA G530012D1 gene
chrX_+_162923474 Show fit	4.83	ENSMUST00000073973.11	Ace2 Ensembl NCBI MGI UniProt Show fit	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr17_-_35407403 Show fit	4.82	ENSMUST00000097336.5	Lst1 Ensembl NCBI MGI UniProt Show fit	leukocyte specific transcript 1
chr15_-_76554065 Show fit	4.81	ENSMUST00000037824.6	Foxh1 Ensembl NCBI MGI UniProt Show fit	forkhead box H1
chr7_-_126831803 Show fit	4.80	ENSMUST00000133913.8	Septin1 Ensembl NCBI MGI UniProt Show fit	septin 1
chr5_-_24760401 Show fit	4.76	ENSMUST00000088302.10	Iqca1l Ensembl NCBI MGI UniProt Show fit	IQ motif containing with AAA domain 1 like
chr7_-_30119227 Show fit	4.73	ENSMUST00000208740.2 ENSMUST00000075062.5	Hcst Ensembl NCBI MGI UniProt Show fit	hematopoietic cell signal transducer
chr16_+_9988080 Show fit	4.73	ENSMUST00000121292.8 ENSMUST00000044103.6	Rpl39l Ensembl NCBI MGI UniProt Show fit	ribosomal protein L39-like
chr1_-_73055043 Show fit	4.72	ENSMUST00000027374.7	Tnp1 Ensembl NCBI MGI UniProt Show fit	transition protein 1
chr12_-_66331168 Show fit	4.70	ENSMUST00000081908.8	Rpl10l Ensembl NCBI MGI UniProt Show fit	ribosomal protein L10-like
chr7_+_12246415 Show fit	4.69	ENSMUST00000032541.5	2900092C05Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 2900092C05 gene
chr6_+_41510925 Show fit	4.69	ENSMUST00000103285.2	Trbj1-2 Ensembl NCBI MGI UniProt Show fit	T cell receptor beta joining 1-2
chr16_+_93629009 Show fit	4.66	ENSMUST00000044068.10 ENSMUST00000202261.5 ENSMUST00000201097.3	Morc3 Ensembl NCBI MGI UniProt Show fit	microrchidia 3
chr14_+_71011744 Show fit	4.60	ENSMUST00000022698.8	Dok2 Ensembl NCBI MGI UniProt Show fit	docking protein 2
chr18_+_57666852 Show fit	4.57	ENSMUST00000079738.10 ENSMUST00000135806.8 ENSMUST00000127130.9	Ccdc192 Ensembl NCBI MGI UniProt Show fit	coiled-coil domain containing 192
chr6_+_41511733 Show fit	4.57	ENSMUST00000103287.2	Trbj1-4 Ensembl NCBI MGI UniProt Show fit	T cell receptor beta joining 1-4
chr17_+_30940015 Show fit	4.55	ENSMUST00000236948.2	Dnah8 Ensembl NCBI MGI UniProt Show fit	dynein, axonemal, heavy chain 8
chr10_+_75790348 Show fit	4.55	ENSMUST00000099577.4	Gm5134 Ensembl NCBI MGI UniProt Show fit	predicted gene 5134
chr10_+_117977822 Show fit	4.50	ENSMUST00000164077.9 ENSMUST00000169817.3	Mdm1 Ensembl NCBI MGI UniProt Show fit	transformed mouse 3T3 cell double minute 1
chr14_+_53093071 Show fit	4.49	ENSMUST00000181038.3 ENSMUST00000187138.2	Trav14d-1 Ensembl NCBI MGI UniProt Show fit	T cell receptor alpha variable 14D-1
chr15_+_102315579 Show fit	4.48	ENSMUST00000169619.2	Sp1 Ensembl NCBI MGI UniProt Show fit	trans-acting transcription factor 1
chr11_+_72205264 Show fit	4.46	ENSMUST00000108504.2	Fbxo39 Ensembl NCBI MGI UniProt Show fit	F-box protein 39
chr18_-_74340842 Show fit	4.46	ENSMUST00000040188.16	Ska1 Ensembl NCBI MGI UniProt Show fit	spindle and kinetochore associated complex subunit 1
chr11_-_73029070 Show fit	4.44	ENSMUST00000052140.3	Haspin Ensembl NCBI MGI UniProt Show fit	histone H3 associated protein kinase
chr6_+_35154319 Show fit	4.44	ENSMUST00000201374.4 ENSMUST00000043815.16	Nup205 Ensembl NCBI MGI UniProt Show fit	nucleoporin 205
chr19_+_34899752 Show fit	4.36	ENSMUST00000087341.7	Kif20b Ensembl NCBI MGI UniProt Show fit	kinesin family member 20B
chr3_+_30910089 Show fit	4.35	ENSMUST00000108261.8 ENSMUST00000108259.8 ENSMUST00000166278.7 ENSMUST00000046748.13 ENSMUST00000194979.6	Gpr160 Ensembl NCBI MGI UniProt Show fit	G protein-coupled receptor 160
chr10_+_20223516 Show fit	4.32	ENSMUST00000169712.3 ENSMUST00000217608.2	Mtfr2 Ensembl NCBI MGI UniProt Show fit	mitochondrial fission regulator 2
chr16_-_64299511 Show fit	4.31	ENSMUST00000089279.5	Csnka2ip Ensembl NCBI MGI UniProt Show fit	casein kinase 2, alpha prime interacting protein
chr12_-_112824506 Show fit	4.30	ENSMUST00000021729.9	Gpr132 Ensembl NCBI MGI UniProt Show fit	G protein-coupled receptor 132
chr19_+_34899778 Show fit	4.30	ENSMUST00000223907.2	Kif20b Ensembl NCBI MGI UniProt Show fit	kinesin family member 20B
chr5_+_138278777 Show fit	4.30	ENSMUST00000048028.15 ENSMUST00000162245.8 ENSMUST00000161691.2	Stag3 Ensembl NCBI MGI UniProt Show fit	stromal antigen 3
chr10_+_79722081 Show fit	4.30	ENSMUST00000046091.7	Elane Ensembl NCBI MGI UniProt Show fit	elastase, neutrophil expressed
chr9_-_40915858 Show fit	4.27	ENSMUST00000188848.8 ENSMUST00000034519.13	Crtam Ensembl NCBI MGI UniProt Show fit	cytotoxic and regulatory T cell molecule
chr6_+_47897410 Show fit	4.24	ENSMUST00000009411.9	Zfp212 Ensembl NCBI MGI UniProt Show fit	Zinc finger protein 212
chr3_-_94343874 Show fit	4.24	ENSMUST00000204913.3 ENSMUST00000191506.8 ENSMUST00000199678.4	Oaz3 Ensembl NCBI MGI UniProt Show fit	ornithine decarboxylase antizyme 3
chr1_+_34537450 Show fit	4.19	ENSMUST00000027299.10	Prss39 Ensembl NCBI MGI UniProt Show fit	protease, serine 39
chr14_+_54380308 Show fit	4.19	ENSMUST00000196323.2	Trdc Ensembl NCBI MGI UniProt Show fit	T cell receptor delta, constant region
chr1_-_128520002 Show fit	4.18	ENSMUST00000052172.7 ENSMUST00000142893.2	Cxcr4 Ensembl NCBI MGI UniProt Show fit	chemokine (C-X-C motif) receptor 4
chr17_+_35286293 Show fit	4.16	ENSMUST00000173478.2 ENSMUST00000174876.2	Ly6g6c Ensembl NCBI MGI UniProt Show fit	lymphocyte antigen 6 complex, locus G6C
chr10_+_61011164 Show fit	4.16	ENSMUST00000140456.2	Tbata Ensembl NCBI MGI UniProt Show fit	thymus, brain and testes associated
chr10_-_75658355 Show fit	4.14	ENSMUST00000160211.2	Gstt4 Ensembl NCBI MGI UniProt Show fit	glutathione S-transferase, theta 4
chr17_-_25946370 Show fit	4.12	ENSMUST00000170070.3 ENSMUST00000048054.14	Chtf18 Ensembl NCBI MGI UniProt Show fit	CTF18, chromosome transmission fidelity factor 18
chr4_+_156194427 Show fit	4.10	ENSMUST00000072554.13 ENSMUST00000169550.8 ENSMUST00000105576.2	9430015G10Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 9430015G10 gene
chr3_-_36107661 Show fit	4.08	ENSMUST00000166644.8 ENSMUST00000200469.5	Ccdc144b Ensembl NCBI MGI UniProt Show fit	coiled-coil domain containing 144B
chr3_-_90150393 Show fit	4.08	ENSMUST00000107369.2	Creb3l4 Ensembl NCBI MGI UniProt Show fit	cAMP responsive element binding protein 3-like 4
chr5_+_93354377 Show fit	4.06	ENSMUST00000031330.5	2010109A12Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 2010109A12 gene
chr9_-_114325630 Show fit	4.06	ENSMUST00000054414.5	Ccr4 Ensembl NCBI MGI UniProt Show fit	chemokine (C-C motif) receptor 4
chr5_-_100720063 Show fit	4.02	ENSMUST00000031264.12	Plac8 Ensembl NCBI MGI UniProt Show fit	placenta-specific 8
chr19_-_5444413 Show fit	4.02	ENSMUST00000044527.5	Tsga10ip Ensembl NCBI MGI UniProt Show fit	testis specific 10 interacting protein
chr6_+_41512480 Show fit	4.01	ENSMUST00000103289.2 ENSMUST00000103290.2 ENSMUST00000193061.2	Trbj1-6 Ensembl NCBI MGI UniProt Show fit Trbj1-7 Ensembl NCBI MGI UniProt Show fit	T cell receptor beta joining 1-6 T cell receptor beta joining 1-7
chr11_-_54968947 Show fit	3.99	ENSMUST00000108880.2	Ccdc69 Ensembl NCBI MGI UniProt Show fit	coiled-coil domain containing 69
chr10_-_80374941 Show fit	3.98	ENSMUST00000020383.6	Atp8b3 Ensembl NCBI MGI UniProt Show fit	ATPase, class I, type 8B, member 3
chr11_+_117672902 Show fit	3.97	ENSMUST00000127080.9	Tmc8 Ensembl NCBI MGI UniProt Show fit	transmembrane channel-like gene family 8
chr12_+_71184614 Show fit	3.97	ENSMUST00000045907.16	2700049A03Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 2700049A03 gene
chr8_+_85628557 Show fit	3.96	ENSMUST00000067060.10 ENSMUST00000239392.2	Klf1 Ensembl NCBI MGI UniProt Show fit	Kruppel-like factor 1 (erythroid)
chr14_+_51366512 Show fit	3.94	ENSMUST00000095923.4	Rnase6 Ensembl NCBI MGI UniProt Show fit	ribonuclease, RNase A family, 6
chr11_-_102815910 Show fit	3.94	ENSMUST00000021311.10	Kif18b Ensembl NCBI MGI UniProt Show fit	kinesin family member 18B
chr1_-_156168522 Show fit	3.94	ENSMUST00000212747.2	Axdnd1 Ensembl NCBI MGI UniProt Show fit	axonemal dynein light chain domain containing 1
chr5_-_143831842 Show fit	3.94	ENSMUST00000079624.12 ENSMUST00000110717.9	Ankrd61 Ensembl NCBI MGI UniProt Show fit	ankyrin repeat domain 61
chr6_+_72521374 Show fit	3.94	ENSMUST00000071044.13 ENSMUST00000114072.8	Capg Ensembl NCBI MGI UniProt Show fit	capping protein (actin filament), gelsolin-like
chr4_+_130640436 Show fit	3.92	ENSMUST00000151698.8	Laptm5 Ensembl NCBI MGI UniProt Show fit	lysosomal-associated protein transmembrane 5
chr17_+_6869070 Show fit	3.92	ENSMUST00000092966.5	Dynlt1c Ensembl NCBI MGI UniProt Show fit	dynein light chain Tctex-type 1C
chr3_+_105778174 Show fit	3.90	ENSMUST00000164730.2 ENSMUST00000010279.10	Adora3 Ensembl NCBI MGI UniProt Show fit Tmigd3 Ensembl NCBI MGI UniProt Show fit	adenosine A3 receptor transmembrane and immunoglobulin domain containing 3
chr9_+_21437440 Show fit	3.89	ENSMUST00000086361.12 ENSMUST00000173769.3	AB124611 Ensembl NCBI MGI UniProt Show fit	cDNA sequence AB124611
chr16_+_8498618 Show fit	3.85	ENSMUST00000201722.2	Gm5767 Ensembl NCBI MGI UniProt Show fit	predicted gene 5767
chr5_-_8472582 Show fit	3.84	ENSMUST00000168500.8 ENSMUST00000002368.16	Dbf4 Ensembl NCBI MGI UniProt Show fit	DBF4 zinc finger
chr1_-_134477400 Show fit	3.83	ENSMUST00000172898.2	Mgat4e Ensembl NCBI MGI UniProt Show fit	MGAT4 family, member E
chr3_-_105839980 Show fit	3.82	ENSMUST00000098758.5	I830077J02Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA I830077J02 gene
chr5_+_134611544 Show fit	3.81	ENSMUST00000023867.8	Rfc2 Ensembl NCBI MGI UniProt Show fit	replication factor C (activator 1) 2
chr19_+_6234392 Show fit	3.80	ENSMUST00000025699.9 ENSMUST00000113528.2	Majin Ensembl NCBI MGI UniProt Show fit	membrane anchored junction protein
chr13_-_12535236 Show fit	3.76	ENSMUST00000179308.3	Edaradd Ensembl NCBI MGI UniProt Show fit	EDAR (ectodysplasin-A receptor)-associated death domain
chr7_-_30371021 Show fit	3.76	ENSMUST00000051495.7	Pmis2 Ensembl NCBI MGI UniProt Show fit	PMIS2 transmembrane protein
chr7_-_45173193 Show fit	3.74	ENSMUST00000211212.2	Ppp1r15a Ensembl NCBI MGI UniProt Show fit	protein phosphatase 1, regulatory subunit 15A
chr1_+_190769010 Show fit	3.74	ENSMUST00000077889.8	Spata45 Ensembl NCBI MGI UniProt Show fit	spermatogenesis associated 45
chr9_-_7873017 Show fit	3.73	ENSMUST00000013949.15	Birc3 Ensembl NCBI MGI UniProt Show fit	baculoviral IAP repeat-containing 3
chr2_-_162929732 Show fit	3.71	ENSMUST00000094653.6	Gtsf1l Ensembl NCBI MGI UniProt Show fit	gametocyte specific factor 1-like
chr15_-_97618982 Show fit	3.70	ENSMUST00000023105.5	Endou Ensembl NCBI MGI UniProt Show fit	endonuclease, polyU-specific
chr6_+_41107047 Show fit	3.69	ENSMUST00000103271.2	Trbv13-3 Ensembl NCBI MGI UniProt Show fit	T cell receptor beta, variable 13-3
chr15_-_98816012 Show fit	3.68	ENSMUST00000023736.10	Lmbr1l Ensembl NCBI MGI UniProt Show fit	limb region 1 like
chr4_+_138503046 Show fit	3.68	ENSMUST00000030528.9	Pla2g2d Ensembl NCBI MGI UniProt Show fit	phospholipase A2, group IID
chr9_+_107869662 Show fit	3.67	ENSMUST00000177173.8	Cdhr4 Ensembl NCBI MGI UniProt Show fit	cadherin-related family member 4
chr17_+_35643818 Show fit	3.64	ENSMUST00000174699.8	H2-Q6 Ensembl NCBI MGI UniProt Show fit	histocompatibility 2, Q region locus 6
chr3_-_95148909 Show fit	3.63	ENSMUST00000090815.6 ENSMUST00000107197.2	Gm128 Ensembl NCBI MGI UniProt Show fit	predicted gene 128
chr14_+_31888061 Show fit	3.61	ENSMUST00000164341.2	Ncoa4 Ensembl NCBI MGI UniProt Show fit	nuclear receptor coactivator 4
chr10_+_128073900 Show fit	3.60	ENSMUST00000105245.3	Timeless Ensembl NCBI MGI UniProt Show fit	timeless circadian clock 1
chrX_+_41591410 Show fit	3.60	ENSMUST00000005839.11	Sh2d1a Ensembl NCBI MGI UniProt Show fit	SH2 domain containing 1A
chr4_+_132903646 Show fit	3.59	ENSMUST00000105912.2	Wasf2 Ensembl NCBI MGI UniProt Show fit	WASP family, member 2
chr8_+_70285133 Show fit	3.59	ENSMUST00000081503.13	Pbx4 Ensembl NCBI MGI UniProt Show fit	pre B cell leukemia homeobox 4
chr5_+_3621673 Show fit	3.58	ENSMUST00000008451.12	1700109H08Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 1700109H08 gene
chr15_-_36598263 Show fit	3.58	ENSMUST00000155116.2	Pabpc1 Ensembl NCBI MGI UniProt Show fit	poly(A) binding protein, cytoplasmic 1
chr2_+_79538124 Show fit	3.57	ENSMUST00000090760.9 ENSMUST00000040863.11 ENSMUST00000111780.3	Ppp1r1c Ensembl NCBI MGI UniProt Show fit	protein phosphatase 1, regulatory inhibitor subunit 1C
chr9_-_78350486 Show fit	3.57	ENSMUST00000070742.14 ENSMUST00000034898.14	Cgas Ensembl NCBI MGI UniProt Show fit	cyclic GMP-AMP synthase
chr14_-_20546848 Show fit	3.55	ENSMUST00000022353.5	Mss51 Ensembl NCBI MGI UniProt Show fit	MSS51 mitochondrial translational activator
chr13_+_19528728 Show fit	3.52	ENSMUST00000179181.3	Trgc4 Ensembl NCBI MGI UniProt Show fit	T cell receptor gamma, constant 4
chr13_-_120677483 Show fit	3.51	ENSMUST00000225881.2	Gm21762 Ensembl NCBI MGI UniProt Show fit	predicted gene, 21762
chr17_-_35984625 Show fit	3.50	ENSMUST00000001565.15	Gtf2h4 Ensembl NCBI MGI UniProt Show fit	general transcription factor II H, polypeptide 4
chr5_-_134485430 Show fit	3.50	ENSMUST00000200944.4 ENSMUST00000202280.4 ENSMUST00000074114.12 ENSMUST00000100654.10 ENSMUST00000100650.10 ENSMUST00000111245.9 ENSMUST00000202554.4 ENSMUST00000073161.12 ENSMUST00000100652.10 ENSMUST00000171794.9 ENSMUST00000167084.9	Gtf2ird1 Ensembl NCBI MGI UniProt Show fit	general transcription factor II I repeat domain-containing 1
chr7_-_24997291 Show fit	3.49	ENSMUST00000148150.8 ENSMUST00000155118.2	Pafah1b3 Ensembl NCBI MGI UniProt Show fit	platelet-activating factor acetylhydrolase, isoform 1b, subunit 3
chr18_+_35932894 Show fit	3.49	ENSMUST00000236484.2 ENSMUST00000236550.2 ENSMUST00000235919.2	Ube2d2a Ensembl NCBI MGI UniProt Show fit Gm50371 Ensembl NCBI MGI UniProt Show fit	ubiquitin-conjugating enzyme E2D 2A predicted gene, 50371
chr3_+_134947971 Show fit	3.47	ENSMUST00000197369.3	Cenpe Ensembl NCBI MGI UniProt Show fit	centromere protein E
chr10_+_128583734 Show fit	3.47	ENSMUST00000163377.10	Pym1 Ensembl NCBI MGI UniProt Show fit	PYM homolog 1, exon junction complex associated factor
chr10_+_80128248 Show fit	3.46	ENSMUST00000068408.14 ENSMUST00000062674.7	Rps15 Ensembl NCBI MGI UniProt Show fit	ribosomal protein S15
chr16_-_10613991 Show fit	3.46	ENSMUST00000189593.2	Prm2 Ensembl NCBI MGI UniProt Show fit	protamine 2
chr2_-_126342551 Show fit	3.46	ENSMUST00000129187.2	Atp8b4 Ensembl NCBI MGI UniProt Show fit	ATPase, class I, type 8B, member 4
chr11_+_117673198 Show fit	3.45	ENSMUST00000117781.8	Tmc8 Ensembl NCBI MGI UniProt Show fit	transmembrane channel-like gene family 8
chr6_+_28427788 Show fit	3.44	ENSMUST00000031719.7	Fscn3 Ensembl NCBI MGI UniProt Show fit	fascin actin-bundling protein 3
chr9_+_21231994 Show fit	3.44	ENSMUST00000217461.2	Slc44a2 Ensembl NCBI MGI UniProt Show fit	solute carrier family 44, member 2
chr6_-_125168637 Show fit	3.44	ENSMUST00000043848.11	Ncapd2 Ensembl NCBI MGI UniProt Show fit	non-SMC condensin I complex, subunit D2
chr8_-_11685726 Show fit	3.43	ENSMUST00000033905.13 ENSMUST00000169782.3	Ankrd10 Ensembl NCBI MGI UniProt Show fit	ankyrin repeat domain 10
chr6_+_68414401 Show fit	3.43	ENSMUST00000103324.3	Igkv15-103 Ensembl NCBI MGI UniProt Show fit	immunoglobulin kappa chain variable 15-103
chr11_-_32150222 Show fit	3.40	ENSMUST00000145401.8 ENSMUST00000142396.2 ENSMUST00000128311.8	Il9r Ensembl NCBI MGI UniProt Show fit	interleukin 9 receptor
chr17_-_29161229 Show fit	3.39	ENSMUST00000051526.6 ENSMUST00000233413.2	Pxt1 Ensembl NCBI MGI UniProt Show fit	peroxisomal, testis specific 1
chr9_-_114811807 Show fit	3.37	ENSMUST00000053150.8	Rps27rt Ensembl NCBI MGI UniProt Show fit	ribosomal protein S27, retrogene
chr6_+_70675416 Show fit	3.36	ENSMUST00000103403.3	Igkv3-2 Ensembl NCBI MGI UniProt Show fit	immunoglobulin kappa variable 3-2
chr13_+_38224201 Show fit	3.35	ENSMUST00000224956.2	Riok1 Ensembl NCBI MGI UniProt Show fit	RIO kinase 1
chr9_+_21249118 Show fit	3.35	ENSMUST00000034697.8	Slc44a2 Ensembl NCBI MGI UniProt Show fit	solute carrier family 44, member 2
chr6_-_113577606 Show fit	3.35	ENSMUST00000035870.5	Fancd2os Ensembl NCBI MGI UniProt Show fit	Fancd2 opposite strand
chr8_-_43594523 Show fit	3.34	ENSMUST00000059692.4	Triml1 Ensembl NCBI MGI UniProt Show fit	tripartite motif family-like 1
chr6_+_145561483 Show fit	3.33	ENSMUST00000087445.7	Tuba3b Ensembl NCBI MGI UniProt Show fit	tubulin, alpha 3B
chrX_-_7956682 Show fit	3.32	ENSMUST00000033505.7	Was Ensembl NCBI MGI UniProt Show fit	Wiskott-Aldrich syndrome

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.1	15.4	GO:0071846	actin filament debranching(GO:0071846)
3.2	16.0	GO:0019516	lactate oxidation(GO:0019516)
3.0	11.9	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
3.0	17.7	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
2.8	11.2	GO:0038096	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
2.3	6.8	GO:0015825	L-serine transport(GO:0015825)
2.3	11.3	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
2.2	6.7	GO:0045004	DNA replication proofreading(GO:0045004)
2.2	8.8	GO:0061152	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
1.9	5.8	GO:0060734	regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
1.8	5.5	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
1.8	5.3	GO:0015688	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
1.7	5.2	GO:0036275	response to 5-fluorouracil(GO:0036275)
1.7	5.0	GO:0002355	detection of tumor cell(GO:0002355)
1.6	7.8	GO:0007066	female meiosis sister chromatid cohesion(GO:0007066)
1.5	7.5	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
1.5	6.0	GO:1904158	axonemal central apparatus assembly(GO:1904158)
1.5	4.5	GO:1904826	regulation of hydrogen sulfide biosynthetic process(GO:1904826) positive regulation of hydrogen sulfide biosynthetic process(GO:1904828)
1.5	4.4	GO:0072356	chromosome passenger complex localization to kinetochore(GO:0072356)
1.4	8.7	GO:1903436	regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
1.4	4.3	GO:0070947	antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780) neutrophil mediated killing of fungus(GO:0070947)
1.4	7.1	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
1.4	8.3	GO:0060474	positive regulation of sperm motility involved in capacitation(GO:0060474)
1.4	2.7	GO:2000547	regulation of dendritic cell dendrite assembly(GO:2000547)
1.2	7.5	GO:2000520	regulation of immunological synapse formation(GO:2000520)
1.2	4.8	GO:0015801	aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
1.2	4.7	GO:1902990	mitotic telomere maintenance via semi-conservative replication(GO:1902990)
1.1	3.4	GO:0071603	endothelial cell-cell adhesion(GO:0071603)
1.1	3.3	GO:0002625	regulation of T cell antigen processing and presentation(GO:0002625)
1.1	3.3	GO:0043988	histone H3-S28 phosphorylation(GO:0043988)
1.1	4.4	GO:0000239	pachytene(GO:0000239)
1.1	6.4	GO:0071350	interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
1.1	7.5	GO:0060335	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
1.1	4.2	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
1.0	3.1	GO:0002344	peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
1.0	2.0	GO:0036337	Fas signaling pathway(GO:0036337)
1.0	5.0	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
1.0	5.0	GO:0071475	cellular hyperosmotic salinity response(GO:0071475)
1.0	7.0	GO:0046116	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
1.0	2.9	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
1.0	4.8	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.9	2.8	GO:1904456	negative regulation of neuronal action potential(GO:1904456)
0.9	4.6	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.9	4.5	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.9	2.7	GO:0010138	CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206) CMP metabolic process(GO:0046035)
0.9	2.7	GO:0030221	basophil differentiation(GO:0030221)
0.9	7.9	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.9	4.3	GO:0007290	spermatid nucleus elongation(GO:0007290)
0.9	1.7	GO:1902523	positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.8	2.5	GO:0060559	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.8	2.5	GO:1904582	positive regulation of intracellular mRNA localization(GO:1904582)
0.8	1.6	GO:0035771	interleukin-4-mediated signaling pathway(GO:0035771)
0.8	6.5	GO:0061621	NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.8	2.4	GO:0018312	peptidyl-serine ADP-ribosylation(GO:0018312)
0.8	5.6	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.8	10.1	GO:0036158	outer dynein arm assembly(GO:0036158)
0.7	2.2	GO:0032685	negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685) negative regulation of interleukin-18 production(GO:0032701)
0.7	3.6	GO:1904976	response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.7	2.1	GO:0001807	regulation of type IV hypersensitivity(GO:0001807)
0.7	1.4	GO:0002589	regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589)
0.7	7.6	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.7	2.1	GO:1903904	negative regulation of establishment of T cell polarity(GO:1903904)
0.7	2.1	GO:0097694	establishment of RNA localization to telomere(GO:0097694)
0.7	14.6	GO:0036297	interstrand cross-link repair(GO:0036297)
0.7	8.6	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
0.6	2.6	GO:0000711	meiotic DNA repair synthesis(GO:0000711)
0.6	2.6	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.6	13.5	GO:0070986	left/right axis specification(GO:0070986)
0.6	1.9	GO:0006714	sesquiterpenoid metabolic process(GO:0006714)
0.6	3.2	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.6	2.5	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.6	3.1	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.6	1.9	GO:0016598	protein arginylation(GO:0016598)
0.6	2.5	GO:0048478	replication fork protection(GO:0048478)
0.6	5.6	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.6	5.4	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.6	3.0	GO:1902340	telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.6	6.0	GO:0031659	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.6	4.1	GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.6	2.9	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
0.6	1.7	GO:1901074	regulation of engulfment of apoptotic cell(GO:1901074)
0.6	1.7	GO:0002426	immunoglobulin production in mucosal tissue(GO:0002426)
0.6	7.9	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.6	3.4	GO:0018094	protein polyglycylation(GO:0018094)
0.6	4.5	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.6	1.7	GO:0006740	NADPH regeneration(GO:0006740)
0.6	3.3	GO:0060369	positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.5	2.2	GO:0002879	positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.5	7.1	GO:0046602	regulation of mitotic centrosome separation(GO:0046602)
0.5	1.6	GO:0001545	primary ovarian follicle growth(GO:0001545)
0.5	1.6	GO:0009597	detection of virus(GO:0009597)
0.5	0.5	GO:0031990	mRNA export from nucleus in response to heat stress(GO:0031990)
0.5	2.2	GO:0034421	post-translational protein acetylation(GO:0034421)
0.5	3.2	GO:0045590	negative regulation of regulatory T cell differentiation(GO:0045590)
0.5	1.6	GO:1903632	positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.5	4.2	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)
0.5	1.6	GO:1990167	protein K27-linked deubiquitination(GO:1990167)
0.5	2.1	GO:0042138	meiotic DNA double-strand break formation(GO:0042138)
0.5	2.1	GO:0071348	cellular response to interleukin-11(GO:0071348)
0.5	1.6	GO:0006788	heme oxidation(GO:0006788)
0.5	3.1	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.5	1.0	GO:0006393	termination of mitochondrial transcription(GO:0006393)
0.5	8.2	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.5	2.5	GO:2000334	response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.5	5.5	GO:0000255	allantoin metabolic process(GO:0000255)
0.5	1.5	GO:0008358	oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
0.5	3.5	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.5	1.5	GO:0002396	MHC protein complex assembly(GO:0002396) peptide antigen assembly with MHC protein complex(GO:0002501)
0.5	3.9	GO:0033277	abortive mitotic cell cycle(GO:0033277)
0.5	1.5	GO:0030961	peptidyl-arginine hydroxylation(GO:0030961)
0.5	2.4	GO:0030578	PML body organization(GO:0030578)
0.5	3.8	GO:0000821	regulation of arginine metabolic process(GO:0000821)
0.5	2.4	GO:0072737	response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.5	1.9	GO:2001270	regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.5	2.8	GO:0090204	protein localization to nuclear pore(GO:0090204)
0.5	6.4	GO:1904659	glucose transmembrane transport(GO:1904659)
0.5	0.9	GO:0070948	regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949)
0.5	2.3	GO:0035547	interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549)
0.4	3.5	GO:0002349	histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.4	4.0	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.4	3.8	GO:0030886	negative regulation of myeloid dendritic cell activation(GO:0030886)
0.4	4.2	GO:0035701	hematopoietic stem cell migration(GO:0035701)
0.4	1.7	GO:0036228	protein targeting to nuclear inner membrane(GO:0036228)
0.4	2.1	GO:1901355	response to rapamycin(GO:1901355)
0.4	14.1	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.4	2.9	GO:0032466	negative regulation of cytokinesis(GO:0032466)
0.4	5.2	GO:0051255	spindle midzone assembly(GO:0051255)
0.4	6.4	GO:0006968	cellular defense response(GO:0006968)
0.4	3.6	GO:0090070	positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.4	3.2	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.4	1.6	GO:1901837	negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.4	1.1	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.4	10.8	GO:0032460	negative regulation of protein oligomerization(GO:0032460)
0.4	3.0	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.4	5.2	GO:0050957	equilibrioception(GO:0050957)
0.4	0.4	GO:0071033	nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.3	9.4	GO:0097340	inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.3	8.0	GO:0045332	phospholipid translocation(GO:0045332)
0.3	3.4	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.3	1.0	GO:0097045	activation of blood coagulation via clotting cascade(GO:0002543) phosphatidylserine exposure on blood platelet(GO:0097045)
0.3	5.1	GO:0071294	cellular response to zinc ion(GO:0071294)
0.3	1.0	GO:0001180	transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.3	6.4	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.3	3.0	GO:0070197	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.3	5.3	GO:1903546	protein localization to photoreceptor outer segment(GO:1903546)
0.3	5.2	GO:0030259	lipid glycosylation(GO:0030259)
0.3	6.1	GO:0006662	glycerol ether metabolic process(GO:0006662)
0.3	2.9	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.3	4.2	GO:0046599	regulation of centriole replication(GO:0046599)
0.3	1.9	GO:2000680	regulation of rubidium ion transport(GO:2000680)
0.3	1.9	GO:0019364	pyridine nucleotide catabolic process(GO:0019364)
0.3	1.3	GO:0046351	disaccharide biosynthetic process(GO:0046351)
0.3	0.6	GO:1990918	double-strand break repair involved in meiotic recombination(GO:1990918)
0.3	8.4	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.3	1.9	GO:0032824	negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.3	5.2	GO:0043249	erythrocyte maturation(GO:0043249)
0.3	2.5	GO:0010897	negative regulation of triglyceride catabolic process(GO:0010897)
0.3	1.2	GO:0006361	transcription initiation from RNA polymerase I promoter(GO:0006361) termination of RNA polymerase I transcription(GO:0006363)
0.3	2.9	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.3	0.9	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.3	0.3	GO:1990168	protein K33-linked deubiquitination(GO:1990168)
0.3	2.3	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.3	2.6	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.3	1.4	GO:0090383	phagosome acidification(GO:0090383)
0.3	2.0	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.3	3.3	GO:0051026	chiasma assembly(GO:0051026)
0.3	3.9	GO:0033004	negative regulation of mast cell activation(GO:0033004)
0.3	3.0	GO:2000580	regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.3	1.4	GO:2000354	regulation of ovarian follicle development(GO:2000354)
0.3	2.7	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.3	0.8	GO:1905223	epicardium morphogenesis(GO:1905223)
0.3	10.8	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.3	1.1	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.3	1.1	GO:1900110	negative regulation of histone H3-K9 dimethylation(GO:1900110)
0.3	2.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.3	1.8	GO:0019262	N-acetylneuraminate catabolic process(GO:0019262)
0.3	0.8	GO:0060060	post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.3	1.3	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.3	2.5	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
0.3	5.3	GO:0006999	nuclear pore organization(GO:0006999)
0.2	1.5	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.2	1.0	GO:1904245	regulation of polynucleotide adenylyltransferase activity(GO:1904245) positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.2	3.9	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.2	2.4	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.2	4.1	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.2	2.4	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654)
0.2	2.9	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.2	0.7	GO:0048817	negative regulation of hair follicle maturation(GO:0048817)
0.2	1.4	GO:0070309	lens fiber cell morphogenesis(GO:0070309)
0.2	2.1	GO:0071231	neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.2	0.9	GO:0043328	protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.2	3.2	GO:0034472	snRNA 3'-end processing(GO:0034472)
0.2	0.9	GO:0002248	wound healing involved in inflammatory response(GO:0002246) connective tissue replacement involved in inflammatory response wound healing(GO:0002248) inflammatory response to wounding(GO:0090594)
0.2	5.9	GO:0035855	megakaryocyte development(GO:0035855)
0.2	1.4	GO:0015817	histidine transport(GO:0015817)
0.2	0.9	GO:0036506	maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.2	3.8	GO:0006622	protein targeting to lysosome(GO:0006622)
0.2	0.9	GO:0036367	adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.2	0.9	GO:0042908	glutathione transport(GO:0034635) xenobiotic transport(GO:0042908) tripeptide transport(GO:0042939)
0.2	1.5	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.2	4.6	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.2	1.5	GO:2001180	negative regulation of interleukin-10 secretion(GO:2001180)
0.2	1.1	GO:0032917	polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.2	2.1	GO:2000348	regulation of CD40 signaling pathway(GO:2000348)
0.2	0.2	GO:0045643	regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.2	0.6	GO:0098974	postsynaptic actin cytoskeleton organization(GO:0098974)
0.2	1.0	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.2	0.8	GO:0030450	regulation of complement activation, classical pathway(GO:0030450)
0.2	0.6	GO:0098749	cerebellar neuron development(GO:0098749)
0.2	2.0	GO:1903862	positive regulation of oxidative phosphorylation(GO:1903862)
0.2	2.0	GO:0097475	motor neuron migration(GO:0097475)
0.2	0.6	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.2	1.0	GO:0034224	cellular response to zinc ion starvation(GO:0034224)
0.2	1.0	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2	1.8	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.2	2.1	GO:2000653	regulation of genetic imprinting(GO:2000653)
0.2	1.2	GO:0001980	regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.2	0.6	GO:0001788	antibody-dependent cellular cytotoxicity(GO:0001788)
0.2	1.2	GO:0060744	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.2	10.3	GO:0043029	T cell homeostasis(GO:0043029)
0.2	2.8	GO:0061469	regulation of type B pancreatic cell proliferation(GO:0061469)
0.2	0.7	GO:0035524	proline transmembrane transport(GO:0035524)
0.2	1.1	GO:0097647	calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2	1.7	GO:0098909	regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.2	1.5	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.2	1.5	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.2	2.5	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.2	1.4	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.2	0.9	GO:2000359	regulation of binding of sperm to zona pellucida(GO:2000359)
0.2	2.1	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.2	4.5	GO:0042572	retinol metabolic process(GO:0042572)
0.2	0.9	GO:0070829	heterochromatin maintenance(GO:0070829)
0.2	2.8	GO:0003283	atrial septum development(GO:0003283)
0.2	1.4	GO:0006527	arginine catabolic process(GO:0006527)
0.2	0.7	GO:0006004	fucose metabolic process(GO:0006004)
0.2	1.6	GO:0030916	otic vesicle formation(GO:0030916)
0.2	6.1	GO:0032814	regulation of natural killer cell activation(GO:0032814)
0.2	2.1	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.2	1.0	GO:0098535	de novo centriole assembly(GO:0098535)
0.2	0.5	GO:2000393	negative regulation of lamellipodium morphogenesis(GO:2000393)
0.2	2.4	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.2	0.9	GO:0048539	bone marrow development(GO:0048539)
0.2	2.8	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.2	2.8	GO:0031498	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498)
0.2	0.9	GO:0060160	negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.2	2.4	GO:0050908	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.2	4.1	GO:0002507	tolerance induction(GO:0002507)
0.1	7.4	GO:0016572	histone phosphorylation(GO:0016572)
0.1	1.8	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.1	4.3	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1	6.2	GO:0030317	sperm motility(GO:0030317)
0.1	0.6	GO:0051799	negative regulation of hair follicle development(GO:0051799)
0.1	2.0	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.1	0.7	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.1	0.7	GO:0070945	neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.1	1.3	GO:0042637	catagen(GO:0042637)
0.1	2.7	GO:0034587	piRNA metabolic process(GO:0034587)
0.1	0.7	GO:0060931	sinoatrial node cell development(GO:0060931)
0.1	1.7	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1	0.8	GO:0001905	activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
0.1	1.0	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
0.1	1.2	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.1	1.9	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	1.9	GO:0060352	cell adhesion molecule production(GO:0060352)
0.1	1.2	GO:0061087	positive regulation of histone H3-K27 methylation(GO:0061087)
0.1	1.5	GO:0071763	nuclear membrane organization(GO:0071763)
0.1	4.2	GO:0007140	male meiosis(GO:0007140)
0.1	2.0	GO:0015816	glycine transport(GO:0015816)
0.1	2.9	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.1	0.4	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.1	2.4	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1	0.3	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.1	5.2	GO:0000132	establishment of mitotic spindle orientation(GO:0000132)
0.1	7.2	GO:0045576	mast cell activation(GO:0045576)
0.1	0.1	GO:0005984	disaccharide metabolic process(GO:0005984)
0.1	1.3	GO:0070243	regulation of thymocyte apoptotic process(GO:0070243)
0.1	5.5	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.1	0.9	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1	2.1	GO:0007288	sperm axoneme assembly(GO:0007288)
0.1	0.5	GO:0030382	sperm mitochondrion organization(GO:0030382)
0.1	5.8	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1	6.7	GO:0042462	eye photoreceptor cell development(GO:0042462)
0.1	20.6	GO:0048515	spermatid differentiation(GO:0048515)
0.1	1.5	GO:0016446	somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1	0.7	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.1	1.6	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.1	3.7	GO:0001562	response to protozoan(GO:0001562)
0.1	0.4	GO:1904266	regulation of Schwann cell chemotaxis(GO:1904266) positive regulation of Schwann cell chemotaxis(GO:1904268) Schwann cell chemotaxis(GO:1990751)
0.1	2.4	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1	1.2	GO:0098792	xenophagy(GO:0098792)
0.1	0.9	GO:0035902	response to immobilization stress(GO:0035902)
0.1	0.5	GO:1900533	medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1	1.5	GO:2001204	regulation of osteoclast development(GO:2001204)
0.1	2.7	GO:0071539	protein localization to centrosome(GO:0071539)
0.1	44.4	GO:0007283	spermatogenesis(GO:0007283)
0.1	0.8	GO:2000628	regulation of miRNA metabolic process(GO:2000628)
0.1	1.7	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.1	0.7	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.1	1.9	GO:0051382	kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383)
0.1	3.5	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.1	3.6	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894)
0.1	0.3	GO:0015898	amiloride transport(GO:0015898) cellular response to copper ion starvation(GO:0035874) response to azide(GO:0097184) cellular response to azide(GO:0097185)
0.1	4.7	GO:0002181	cytoplasmic translation(GO:0002181)
0.1	0.7	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1	1.3	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.1	1.4	GO:0070933	histone H4 deacetylation(GO:0070933)
0.1	0.9	GO:0042574	retinal metabolic process(GO:0042574)
0.1	2.3	GO:0010569	regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1	1.0	GO:0006303	double-strand break repair via nonhomologous end joining(GO:0006303)
0.1	3.6	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1	6.1	GO:0050829	defense response to Gram-negative bacterium(GO:0050829)
0.1	0.3	GO:0042262	DNA protection(GO:0042262) dATP catabolic process(GO:0046061)
0.1	1.1	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1	1.4	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.1	1.6	GO:0052312	modulation by host of viral transcription(GO:0043921) modulation of transcription in other organism involved in symbiotic interaction(GO:0052312) modulation by host of symbiont transcription(GO:0052472)
0.1	6.2	GO:1901799	negative regulation of proteasomal protein catabolic process(GO:1901799)
0.1	0.6	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.1	3.3	GO:0003341	cilium movement(GO:0003341)
0.1	2.0	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.1	0.4	GO:0090222	centrosome-templated microtubule nucleation(GO:0090222)
0.1	0.9	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.1	3.4	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1	0.7	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.1	0.7	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1	1.5	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.1	0.7	GO:0042427	serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1	5.5	GO:0006893	Golgi to plasma membrane transport(GO:0006893)
0.1	1.0	GO:0001783	B cell apoptotic process(GO:0001783)
0.1	1.2	GO:0006590	thyroid hormone generation(GO:0006590)
0.1	0.7	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.1	1.1	GO:0036065	fucosylation(GO:0036065)
0.1	1.0	GO:0009068	aspartate family amino acid catabolic process(GO:0009068)
0.1	0.4	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.1	0.8	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.1	0.6	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1	2.4	GO:0018345	protein palmitoylation(GO:0018345)
0.1	1.8	GO:0030220	platelet formation(GO:0030220)
0.1	0.3	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1	0.7	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.1	0.4	GO:1903003	positive regulation of protein deubiquitination(GO:1903003)
0.1	0.9	GO:1902260	negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.1	10.1	GO:0006958	complement activation, classical pathway(GO:0006958)
0.1	0.5	GO:0033504	floor plate development(GO:0033504)
0.1	0.7	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1	1.6	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1	1.1	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1	1.1	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.1	0.6	GO:0036006	response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.1	1.6	GO:0015804	neutral amino acid transport(GO:0015804)
0.1	3.5	GO:0016925	protein sumoylation(GO:0016925)
0.1	0.7	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1	0.6	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1	1.4	GO:0030225	macrophage differentiation(GO:0030225)
0.1	0.6	GO:0006228	UTP biosynthetic process(GO:0006228)
0.1	0.1	GO:0000390	spliceosomal complex disassembly(GO:0000390)
0.1	0.4	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1	0.7	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.1	1.1	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.1	0.4	GO:0021764	amygdala development(GO:0021764)
0.1	0.4	GO:0072619	interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1	6.3	GO:0007276	gamete generation(GO:0007276)
0.1	12.1	GO:0007059	chromosome segregation(GO:0007059)
0.1	4.7	GO:0051865	protein autoubiquitination(GO:0051865)
0.1	1.8	GO:0060713	labyrinthine layer morphogenesis(GO:0060713)
0.1	0.9	GO:0032793	positive regulation of CREB transcription factor activity(GO:0032793)
0.1	0.2	GO:0090187	positive regulation of pancreatic juice secretion(GO:0090187)
0.1	0.5	GO:0086073	cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1	1.9	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.1	0.7	GO:0060019	radial glial cell differentiation(GO:0060019)
0.1	0.6	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.1	1.9	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.1	0.2	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1	0.7	GO:0015747	urate transport(GO:0015747)
0.1	0.2	GO:0070317	negative regulation of G0 to G1 transition(GO:0070317)
0.1	1.3	GO:0021511	spinal cord patterning(GO:0021511)
0.0	4.4	GO:0001824	blastocyst development(GO:0001824)
0.0	2.8	GO:0043966	histone H3 acetylation(GO:0043966)
0.0	0.2	GO:0072318	clathrin coat disassembly(GO:0072318)
0.0	0.9	GO:0046085	adenosine metabolic process(GO:0046085)
0.0	0.6	GO:0045671	negative regulation of osteoclast differentiation(GO:0045671)
0.0	0.4	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	2.1	GO:0051225	spindle assembly(GO:0051225)
0.0	0.2	GO:0044805	late nucleophagy(GO:0044805)
0.0	0.9	GO:0050884	neuromuscular process controlling posture(GO:0050884)
0.0	0.5	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0	0.5	GO:0070633	transepithelial transport(GO:0070633)
0.0	0.3	GO:1904153	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0	0.3	GO:0003096	renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0	0.8	GO:0071470	cellular response to osmotic stress(GO:0071470)
0.0	0.4	GO:0071361	cellular response to ethanol(GO:0071361)
0.0	0.2	GO:0018992	germ-line sex determination(GO:0018992)
0.0	2.0	GO:0035690	cellular response to drug(GO:0035690)
0.0	0.3	GO:0090343	positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774)
0.0	4.7	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0	8.8	GO:0008360	regulation of cell shape(GO:0008360)
0.0	0.7	GO:0098586	cellular response to virus(GO:0098586)
0.0	1.4	GO:0006458	'de novo' protein folding(GO:0006458)
0.0	1.0	GO:1902117	positive regulation of organelle assembly(GO:1902117)
0.0	0.1	GO:0070268	cornification(GO:0070268)
0.0	2.5	GO:0050715	positive regulation of cytokine secretion(GO:0050715)
0.0	1.4	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0	0.5	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.2	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.0	1.5	GO:0009250	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0	5.9	GO:0060271	cilium morphogenesis(GO:0060271)
0.0	0.7	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.0	2.8	GO:0006310	DNA recombination(GO:0006310)
0.0	0.1	GO:0036015	response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0	1.5	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043122)
0.0	1.3	GO:0050766	positive regulation of phagocytosis(GO:0050766)
0.0	2.2	GO:0046579	positive regulation of Ras protein signal transduction(GO:0046579)
0.0	0.4	GO:0032211	negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0	4.0	GO:0042742	defense response to bacterium(GO:0042742)
0.0	0.1	GO:0006780	uroporphyrinogen III biosynthetic process(GO:0006780)
0.0	0.4	GO:0098780	macromitophagy(GO:0000423) response to mitochondrial depolarisation(GO:0098780)
0.0	0.0	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0	0.3	GO:0042074	cell migration involved in gastrulation(GO:0042074)
0.0	0.2	GO:0035067	negative regulation of histone acetylation(GO:0035067)
0.0	2.0	GO:0006749	glutathione metabolic process(GO:0006749)
0.0	0.1	GO:0098751	bone cell development(GO:0098751)
0.0	0.1	GO:0042640	anagen(GO:0042640)
0.0	0.3	GO:0016926	protein desumoylation(GO:0016926)
0.0	1.4	GO:0070830	bicellular tight junction assembly(GO:0070830)
0.0	0.2	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.7	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.0	2.3	GO:0043149	contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0	4.2	GO:0002377	immunoglobulin production(GO:0002377)
0.0	0.3	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.0	0.1	GO:0044331	cell-cell adhesion mediated by cadherin(GO:0044331)
0.0	1.2	GO:0070527	platelet aggregation(GO:0070527)
0.0	0.4	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.4	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.0	0.1	GO:0034552	respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0	3.4	GO:0009615	response to virus(GO:0009615)
0.0	2.1	GO:0042476	odontogenesis(GO:0042476)
0.0	0.2	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0	2.0	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.0	2.8	GO:0030307	positive regulation of cell growth(GO:0030307)
0.0	0.2	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.0	0.6	GO:1901998	toxin transport(GO:1901998)
0.0	1.7	GO:0090630	activation of GTPase activity(GO:0090630)
0.0	0.4	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.0	0.3	GO:0051893	regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109) regulation of adherens junction organization(GO:1903391)
0.0	0.2	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0	1.2	GO:0007338	single fertilization(GO:0007338)
0.0	0.5	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.0	0.1	GO:0051601	exocyst localization(GO:0051601)
0.0	0.3	GO:0006833	water transport(GO:0006833)
0.0	0.2	GO:0016180	snRNA processing(GO:0016180)
0.0	0.4	GO:0007602	phototransduction(GO:0007602)
0.0	0.0	GO:0046462	monoacylglycerol metabolic process(GO:0046462)
0.0	0.4	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.2	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.1	GO:1900060	negative regulation of ceramide biosynthetic process(GO:1900060)
0.0	0.2	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051) gamma-aminobutyric acid transport(GO:0015812)
0.0	0.3	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.3	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.1	GO:0051642	centrosome localization(GO:0051642)
0.0	0.0	GO:0009233	menaquinone metabolic process(GO:0009233)
0.0	0.2	GO:0000338	protein deneddylation(GO:0000338)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.0	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.0	0.3	GO:0043252	sodium-independent organic anion transport(GO:0043252)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.8	11.1	GO:0071821	FANCM-MHF complex(GO:0071821)
1.7	5.2	GO:0097132	cyclin D2-CDK6 complex(GO:0097132)
1.6	7.8	GO:0000802	transverse filament(GO:0000802)
1.5	7.5	GO:0034687	integrin alphaL-beta2 complex(GO:0034687)
1.5	4.4	GO:0005668	RNA polymerase transcription factor SL1 complex(GO:0005668)
1.4	8.5	GO:0032133	chromosome passenger complex(GO:0032133)
1.3	6.7	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
1.2	8.4	GO:0044611	nuclear pore inner ring(GO:0044611)
1.0	3.1	GO:0005760	gamma DNA polymerase complex(GO:0005760)
1.0	4.8	GO:0032444	activin responsive factor complex(GO:0032444)
0.9	21.5	GO:0005652	nuclear lamina(GO:0005652)
0.9	3.5	GO:0000438	core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.8	5.0	GO:0043564	Ku70:Ku80 complex(GO:0043564)
0.8	7.9	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.7	2.2	GO:0070992	translation initiation complex(GO:0070992)
0.7	3.7	GO:0031510	SUMO activating enzyme complex(GO:0031510)
0.7	7.7	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.7	3.4	GO:0000799	nuclear condensin complex(GO:0000799)
0.6	1.9	GO:0031904	endosome lumen(GO:0031904)
0.6	18.6	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.6	6.2	GO:0036157	outer dynein arm(GO:0036157)
0.6	4.9	GO:0001674	female germ cell nucleus(GO:0001674)
0.6	6.1	GO:0001940	male pronucleus(GO:0001940)
0.6	10.2	GO:0001673	male germ cell nucleus(GO:0001673)
0.6	2.8	GO:0010370	perinucleolar chromocenter(GO:0010370)
0.5	7.6	GO:0042612	MHC class I protein complex(GO:0042612)
0.5	7.9	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.5	4.2	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.5	2.1	GO:0060171	stereocilium membrane(GO:0060171)
0.5	2.5	GO:0035363	histone locus body(GO:0035363)
0.5	8.5	GO:1990023	mitotic spindle midzone(GO:1990023)
0.5	2.5	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.5	5.0	GO:0000801	central element(GO:0000801)
0.4	1.3	GO:1990879	CST complex(GO:1990879)
0.4	18.5	GO:0035371	microtubule plus-end(GO:0035371)
0.4	2.9	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.4	6.7	GO:0031616	spindle pole centrosome(GO:0031616)
0.4	5.0	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.4	10.3	GO:0035253	ciliary rootlet(GO:0035253)
0.4	12.9	GO:0001891	phagocytic cup(GO:0001891)
0.4	2.7	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.4	3.9	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.4	4.6	GO:0042613	MHC class II protein complex(GO:0042613)
0.4	5.8	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.4	2.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.4	1.4	GO:0032021	NELF complex(GO:0032021)
0.4	1.1	GO:0009328	phenylalanine-tRNA ligase complex(GO:0009328)
0.3	2.4	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.3	2.1	GO:0070187	telosome(GO:0070187)
0.3	4.3	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.3	3.9	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.3	5.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.3	26.1	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.3	0.9	GO:0000814	ESCRT II complex(GO:0000814)
0.3	2.7	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.3	6.9	GO:0005686	U2 snRNP(GO:0005686)
0.3	43.7	GO:0036126	sperm flagellum(GO:0036126)
0.3	1.4	GO:0043224	nuclear SCF ubiquitin ligase complex(GO:0043224)
0.3	3.9	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.3	2.2	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.3	16.0	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.3	1.6	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.3	3.2	GO:0036156	inner dynein arm(GO:0036156)
0.3	3.9	GO:0090543	Flemming body(GO:0090543)
0.3	1.3	GO:0030690	Noc complex(GO:0030689) Noc1p-Noc2p complex(GO:0030690)
0.3	3.0	GO:0000788	nuclear nucleosome(GO:0000788)
0.2	1.2	GO:0001939	female pronucleus(GO:0001939)
0.2	2.9	GO:0001739	sex chromatin(GO:0001739)
0.2	18.9	GO:0031514	motile cilium(GO:0031514)
0.2	3.4	GO:0044754	autolysosome(GO:0044754)
0.2	9.4	GO:0001741	XY body(GO:0001741)
0.2	3.6	GO:0031209	SCAR complex(GO:0031209)
0.2	9.3	GO:0035145	exon-exon junction complex(GO:0035145)
0.2	1.2	GO:0000439	core TFIIH complex(GO:0000439)
0.2	12.7	GO:0001772	immunological synapse(GO:0001772)
0.2	2.6	GO:0005796	Golgi lumen(GO:0005796)
0.2	2.1	GO:0070652	HAUS complex(GO:0070652)
0.2	6.4	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.2	3.0	GO:0060091	kinocilium(GO:0060091)
0.2	0.9	GO:0005713	recombination nodule(GO:0005713)
0.2	2.9	GO:0031080	nuclear pore outer ring(GO:0031080)
0.2	2.5	GO:0070578	RISC-loading complex(GO:0070578)
0.2	1.8	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.2	0.2	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.2	1.1	GO:0097255	R2TP complex(GO:0097255)
0.2	1.5	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.2	3.7	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.2	2.0	GO:0042629	mast cell granule(GO:0042629)
0.2	2.2	GO:0045179	apical cortex(GO:0045179)
0.2	3.2	GO:0000974	Prp19 complex(GO:0000974)
0.2	1.5	GO:0070847	core mediator complex(GO:0070847)
0.2	0.6	GO:0032545	CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.2	1.1	GO:1903439	calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.2	2.2	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2	0.9	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.2	4.2	GO:0033202	DNA helicase complex(GO:0033202)
0.2	1.4	GO:0042825	TAP complex(GO:0042825)
0.2	3.1	GO:0000786	nucleosome(GO:0000786)
0.2	2.2	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.2	1.6	GO:0016342	catenin complex(GO:0016342)
0.2	0.6	GO:0034271	phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.2	2.4	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.2	2.0	GO:0032009	early phagosome(GO:0032009)
0.2	1.7	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.1	0.9	GO:0002081	outer acrosomal membrane(GO:0002081)
0.1	1.8	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.1	4.2	GO:0005680	anaphase-promoting complex(GO:0005680)
0.1	2.8	GO:0030914	STAGA complex(GO:0030914)
0.1	0.7	GO:0000839	Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1	2.5	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.1	15.0	GO:0005814	centriole(GO:0005814)
0.1	3.3	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.1	2.6	GO:0071564	npBAF complex(GO:0071564)
0.1	19.8	GO:0001669	acrosomal vesicle(GO:0001669)
0.1	0.8	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.1	2.5	GO:0032039	integrator complex(GO:0032039)
0.1	2.9	GO:0005637	nuclear inner membrane(GO:0005637)
0.1	13.4	GO:0000776	kinetochore(GO:0000776)
0.1	3.4	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.1	16.8	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1	1.8	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1	0.6	GO:0000938	GARP complex(GO:0000938) EARP complex(GO:1990745)
0.1	3.2	GO:0097526	spliceosomal tri-snRNP complex(GO:0097526)
0.1	1.0	GO:0042405	nuclear inclusion body(GO:0042405)
0.1	1.3	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.1	3.6	GO:0002102	podosome(GO:0002102)
0.1	0.9	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1	0.9	GO:0030991	intraciliary transport particle A(GO:0030991)
0.1	1.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.1	3.2	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.1	1.0	GO:0071012	U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1	6.5	GO:0005643	nuclear pore(GO:0005643)
0.1	0.4	GO:0005745	m-AAA complex(GO:0005745)
0.1	6.4	GO:0000922	spindle pole(GO:0000922)
0.1	48.4	GO:0009897	external side of plasma membrane(GO:0009897)
0.1	10.9	GO:0017053	transcriptional repressor complex(GO:0017053)
0.1	0.3	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.1	2.4	GO:0042588	zymogen granule(GO:0042588)
0.1	3.3	GO:0043596	nuclear replication fork(GO:0043596)
0.1	0.4	GO:1990923	PET complex(GO:1990923)
0.1	0.8	GO:0016272	prefoldin complex(GO:0016272)
0.1	0.8	GO:0035102	PRC1 complex(GO:0035102)
0.1	17.5	GO:0031965	nuclear membrane(GO:0031965)
0.1	0.9	GO:0032591	dendritic spine membrane(GO:0032591)
0.1	0.3	GO:0046691	intracellular canaliculus(GO:0046691)
0.1	0.4	GO:0005610	laminin-5 complex(GO:0005610)
0.1	6.8	GO:0016605	PML body(GO:0016605)
0.1	0.6	GO:0042382	paraspeckles(GO:0042382)
0.1	0.7	GO:0042788	polysomal ribosome(GO:0042788)
0.1	2.3	GO:0031941	filamentous actin(GO:0031941)
0.1	0.8	GO:0090544	BAF-type complex(GO:0090544)
0.1	0.6	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1	1.2	GO:0035861	site of double-strand break(GO:0035861)
0.1	0.4	GO:0072557	IPAF inflammasome complex(GO:0072557)
0.1	6.4	GO:0030496	midbody(GO:0030496)
0.0	2.4	GO:0045335	phagocytic vesicle(GO:0045335)
0.0	0.4	GO:0097427	microtubule bundle(GO:0097427)
0.0	1.1	GO:0097546	ciliary base(GO:0097546)
0.0	0.5	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.0	0.7	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	4.0	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	3.8	GO:0000781	chromosome, telomeric region(GO:0000781)
0.0	0.2	GO:1990393	3M complex(GO:1990393)
0.0	0.6	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.5	GO:0005916	fascia adherens(GO:0005916)
0.0	1.9	GO:0060170	ciliary membrane(GO:0060170)
0.0	1.8	GO:0000793	condensed chromosome(GO:0000793)
0.0	1.8	GO:0005819	spindle(GO:0005819)
0.0	4.4	GO:0031225	anchored component of membrane(GO:0031225)
0.0	2.4	GO:0014704	intercalated disc(GO:0014704)
0.0	0.4	GO:0032982	myosin filament(GO:0032982)
0.0	0.8	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	4.5	GO:0000795	synaptonemal complex(GO:0000795)
0.0	0.3	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	1.8	GO:0016363	nuclear matrix(GO:0016363)
0.0	0.7	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.2	GO:0030891	VCB complex(GO:0030891)
0.0	0.9	GO:0016592	mediator complex(GO:0016592)
0.0	8.2	GO:0000790	nuclear chromatin(GO:0000790)
0.0	0.2	GO:0000242	pericentriolar material(GO:0000242)
0.0	2.1	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.3	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	1.4	GO:0031985	Golgi cisterna(GO:0031985)
0.0	0.3	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	1.2	GO:0097014	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0	0.5	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.3	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.2	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.2	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0	1.4	GO:0005884	actin filament(GO:0005884)
0.0	3.6	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0	0.1	GO:0033165	interphotoreceptor matrix(GO:0033165)
0.0	0.9	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.4	GO:0005795	Golgi stack(GO:0005795)
0.0	0.8	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.4	GO:0043034	costamere(GO:0043034)
0.0	0.6	GO:0036064	ciliary basal body(GO:0036064)
0.0	0.3	GO:1902711	GABA-A receptor complex(GO:1902711)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	7.0	GO:0098770	FBXO family protein binding(GO:0098770)
1.5	7.5	GO:0030369	ICAM-3 receptor activity(GO:0030369)
1.4	15.7	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
1.2	5.0	GO:0003998	acylphosphatase activity(GO:0003998)
1.2	3.7	GO:0019948	SUMO activating enzyme activity(GO:0019948)
1.1	15.9	GO:0071933	Arp2/3 complex binding(GO:0071933)
1.1	4.4	GO:0072354	histone kinase activity (H3-T3 specific)(GO:0072354)
1.1	6.4	GO:0042289	MHC class II protein binding(GO:0042289)
1.1	4.2	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
1.0	3.1	GO:0016890	site-specific endodeoxyribonuclease activity, specific for altered base(GO:0016890)
1.0	6.8	GO:0047179	platelet-activating factor acetyltransferase activity(GO:0047179)
1.0	18.2	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.8	3.4	GO:0070736	protein-glycine ligase activity, initiating(GO:0070736)
0.8	2.5	GO:0019957	C-C chemokine binding(GO:0019957)
0.8	4.8	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.8	3.2	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.8	19.0	GO:0051010	microtubule plus-end binding(GO:0051010)
0.8	4.7	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.8	4.7	GO:0030171	voltage-gated proton channel activity(GO:0030171)
0.7	3.0	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.7	3.7	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.7	6.5	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.7	7.9	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.7	4.3	GO:0017116	single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.7	3.5	GO:0043515	kinetochore binding(GO:0043515)
0.7	3.5	GO:0030620	U2 snRNA binding(GO:0030620)
0.7	5.5	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.7	6.1	GO:0047134	protein-disulfide reductase activity(GO:0047134)
0.7	2.0	GO:0050785	advanced glycation end-product receptor activity(GO:0050785)
0.7	6.7	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.6	3.9	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
0.6	7.1	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.6	5.0	GO:0008865	fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.6	2.5	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.6	4.2	GO:0030284	estrogen receptor activity(GO:0030284)
0.6	4.2	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.6	4.2	GO:0032027	myosin light chain binding(GO:0032027)
0.6	17.3	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.6	1.8	GO:0070401	NADP+ binding(GO:0070401)
0.6	1.7	GO:0030226	apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.6	17.1	GO:0045503	dynein light chain binding(GO:0045503)
0.6	2.8	GO:0034584	piRNA binding(GO:0034584)
0.5	6.4	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.5	1.6	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
0.5	3.6	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.5	2.5	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
0.5	5.6	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.5	3.5	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.5	9.0	GO:0046977	TAP binding(GO:0046977)
0.5	4.0	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.5	22.0	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.5	9.0	GO:0035174	histone serine kinase activity(GO:0035174)
0.5	1.9	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.5	6.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.5	2.3	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.5	1.8	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.4	4.0	GO:0055104	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.4	7.7	GO:0003688	DNA replication origin binding(GO:0003688)
0.4	1.2	GO:0042015	interleukin-20 binding(GO:0042015)
0.4	1.6	GO:0005136	interleukin-4 receptor binding(GO:0005136)
0.4	2.7	GO:0004849	uridine kinase activity(GO:0004849)
0.4	1.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.4	1.1	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.4	4.8	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.4	7.3	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.4	4.7	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.4	1.4	GO:0032093	SAM domain binding(GO:0032093)
0.3	1.0	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.3	4.0	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.3	3.3	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.3	1.3	GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.3	2.9	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.3	1.3	GO:0051435	BH4 domain binding(GO:0051435)
0.3	6.1	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.3	0.9	GO:0052596	tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.3	8.2	GO:0008179	adenylate cyclase binding(GO:0008179)
0.3	1.9	GO:0016019	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.3	4.8	GO:0008301	DNA binding, bending(GO:0008301)
0.3	0.9	GO:0032190	acrosin binding(GO:0032190)
0.3	0.9	GO:0031531	thyrotropin-releasing hormone receptor binding(GO:0031531)
0.3	0.9	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.3	1.7	GO:0001226	RNA polymerase II transcription corepressor binding(GO:0001226)
0.3	1.1	GO:0019809	spermidine binding(GO:0019809)
0.3	1.0	GO:0051431	corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.3	1.6	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.3	6.4	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.3	2.8	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.3	2.0	GO:0032184	SUMO polymer binding(GO:0032184)
0.3	6.6	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.2	1.5	GO:0051734	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.2	2.5	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.2	5.2	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.2	7.6	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.2	1.0	GO:0034617	tetrahydrobiopterin binding(GO:0034617)
0.2	3.1	GO:0035325	Toll-like receptor binding(GO:0035325)
0.2	1.9	GO:0005499	vitamin D binding(GO:0005499)
0.2	4.2	GO:0003993	acid phosphatase activity(GO:0003993)
0.2	0.9	GO:0036033	mediator complex binding(GO:0036033)
0.2	1.6	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.2	2.0	GO:1901611	phosphatidylglycerol binding(GO:1901611)
0.2	0.7	GO:0004560	alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.2	2.5	GO:0036310	annealing helicase activity(GO:0036310)
0.2	0.7	GO:0004510	tryptophan 5-monooxygenase activity(GO:0004510)
0.2	4.7	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.2	0.9	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.2	4.9	GO:0032183	SUMO binding(GO:0032183)
0.2	6.6	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.2	0.4	GO:0000146	microfilament motor activity(GO:0000146)
0.2	1.5	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.2	2.9	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.2	0.6	GO:0098973	structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.2	2.3	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2	3.1	GO:1990405	protein antigen binding(GO:1990405)
0.2	6.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.2	2.9	GO:0045294	alpha-catenin binding(GO:0045294)
0.2	2.1	GO:0004565	beta-galactosidase activity(GO:0004565)
0.2	5.0	GO:0070410	co-SMAD binding(GO:0070410)
0.2	0.4	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
0.2	7.8	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2	4.8	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.2	2.5	GO:0004000	adenosine deaminase activity(GO:0004000)
0.2	7.2	GO:0070717	poly-purine tract binding(GO:0070717)
0.2	3.5	GO:0035497	cAMP response element binding(GO:0035497)
0.2	3.0	GO:0015299	solute:proton antiporter activity(GO:0015299)
0.2	3.8	GO:0050811	GABA receptor binding(GO:0050811)
0.2	1.9	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.2	8.1	GO:0042169	SH2 domain binding(GO:0042169)
0.2	1.0	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.2	2.4	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.2	1.2	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.2	4.3	GO:0032794	GTPase activating protein binding(GO:0032794)
0.2	3.5	GO:0061650	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.2	32.8	GO:0003735	structural constituent of ribosome(GO:0003735)
0.2	1.6	GO:0004526	ribonuclease P activity(GO:0004526)
0.2	0.6	GO:0016316	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.2	1.5	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453)
0.2	1.4	GO:0004568	chitinase activity(GO:0004568)
0.2	1.7	GO:0005347	ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.2	4.8	GO:0042162	telomeric DNA binding(GO:0042162)
0.1	1.3	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.1	1.0	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.1	0.9	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.1	8.2	GO:0097472	cyclin-dependent protein kinase activity(GO:0097472)
0.1	1.4	GO:0097322	7SK snRNA binding(GO:0097322)
0.1	0.8	GO:0070004	cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.1	4.9	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.1	1.9	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	2.6	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1	5.8	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.1	2.4	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.1	1.4	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.1	0.9	GO:0031750	D3 dopamine receptor binding(GO:0031750)
0.1	4.3	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1	1.2	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.1	2.6	GO:0032036	myosin heavy chain binding(GO:0032036)
0.1	1.1	GO:0004875	complement receptor activity(GO:0004875)
0.1	2.1	GO:0001164	RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1	1.9	GO:0050308	sugar-phosphatase activity(GO:0050308)
0.1	3.5	GO:0015036	disulfide oxidoreductase activity(GO:0015036)
0.1	0.8	GO:0047288	monosialoganglioside sialyltransferase activity(GO:0047288)
0.1	0.6	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.1	1.2	GO:0031014	troponin T binding(GO:0031014)
0.1	0.3	GO:0000403	Y-form DNA binding(GO:0000403)
0.1	1.4	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1	0.7	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1	3.8	GO:0004190	aspartic-type endopeptidase activity(GO:0004190)
0.1	0.8	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.1	4.4	GO:0071837	HMG box domain binding(GO:0071837)
0.1	0.3	GO:0052598	diamine oxidase activity(GO:0052597) histamine oxidase activity(GO:0052598) methylputrescine oxidase activity(GO:0052599) propane-1,3-diamine oxidase activity(GO:0052600)
0.1	1.3	GO:0015266	protein channel activity(GO:0015266)
0.1	0.4	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1	2.1	GO:0070182	DNA polymerase binding(GO:0070182)
0.1	2.5	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.1	2.4	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	0.3	GO:0008413	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.1	0.8	GO:0070883	pre-miRNA binding(GO:0070883)
0.1	1.0	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1	0.6	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.1	6.8	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1	1.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.1	1.6	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.1	4.8	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	4.8	GO:0005044	scavenger receptor activity(GO:0005044)
0.1	0.5	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.1	0.8	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1	3.0	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.1	0.9	GO:0030983	mismatched DNA binding(GO:0030983)
0.1	0.4	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	0.9	GO:0042731	PH domain binding(GO:0042731)
0.1	3.8	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.1	3.1	GO:0051879	Hsp90 protein binding(GO:0051879)
0.1	2.3	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.1	3.4	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.1	0.7	GO:0001594	trace-amine receptor activity(GO:0001594)
0.1	0.7	GO:0043996	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1	2.4	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1	0.2	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
0.1	0.2	GO:0005137	interleukin-5 receptor binding(GO:0005137)
0.1	2.1	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.1	1.2	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.1	2.2	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.1	0.7	GO:0008494	translation activator activity(GO:0008494)
0.1	0.8	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	0.7	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.1	0.9	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.1	4.9	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1	14.8	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1	4.1	GO:0061733	peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.1	2.9	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.1	3.9	GO:0008235	metalloexopeptidase activity(GO:0008235)
0.1	0.2	GO:0034191	apolipoprotein A-I receptor binding(GO:0034191)
0.1	2.9	GO:0004364	glutathione transferase activity(GO:0004364)
0.1	2.4	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	0.4	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	0.2	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.1	1.9	GO:0003785	actin monomer binding(GO:0003785)
0.1	0.2	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.1	0.4	GO:0097603	temperature-gated ion channel activity(GO:0097603)
0.1	1.1	GO:0070628	proteasome binding(GO:0070628)
0.1	0.6	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1	6.9	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.1	0.2	GO:0001032	RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.1	0.2	GO:0019211	phosphatase activator activity(GO:0019211)
0.1	1.3	GO:0043274	phospholipase binding(GO:0043274)
0.1	0.3	GO:0033188	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1	1.0	GO:0003796	lysozyme activity(GO:0003796)
0.1	4.3	GO:0051082	unfolded protein binding(GO:0051082)
0.1	3.6	GO:0019894	kinesin binding(GO:0019894)
0.1	0.6	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1	0.9	GO:0017160	Ral GTPase binding(GO:0017160)
0.1	4.5	GO:0019210	kinase inhibitor activity(GO:0019210)
0.0	2.5	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.5	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0	0.7	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	1.3	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.7	GO:0005521	lamin binding(GO:0005521)
0.0	2.9	GO:0002039	p53 binding(GO:0002039)
0.0	0.1	GO:0042602	riboflavin reductase (NADPH) activity(GO:0042602)
0.0	0.5	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.9	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.7	GO:0015926	glucosidase activity(GO:0015926)
0.0	0.9	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.1	GO:0001607	neuromedin U receptor activity(GO:0001607)
0.0	1.9	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	1.0	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.3	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	3.0	GO:0004519	endonuclease activity(GO:0004519)
0.0	2.1	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	3.1	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.7	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	1.2	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.7	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.9	GO:0035064	methylated histone binding(GO:0035064)
0.0	21.9	GO:0003682	chromatin binding(GO:0003682)
0.0	0.5	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	2.3	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.1	GO:0097157	pre-mRNA intronic binding(GO:0097157)
0.0	1.9	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0	0.5	GO:0045309	protein phosphorylated amino acid binding(GO:0045309)
0.0	0.3	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	1.1	GO:0016504	peptidase activator activity(GO:0016504)
0.0	4.4	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	5.0	GO:0019902	phosphatase binding(GO:0019902)
0.0	8.6	GO:0005516	calmodulin binding(GO:0005516)
0.0	0.3	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	2.3	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.2	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0	0.5	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.2	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.0	0.9	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.6	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	0.9	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.0	0.5	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.4	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.3	GO:0016929	SUMO-specific protease activity(GO:0016929)
0.0	1.4	GO:0003727	single-stranded RNA binding(GO:0003727)
0.0	5.2	GO:0051015	actin filament binding(GO:0051015)
0.0	0.7	GO:0019843	rRNA binding(GO:0019843)
0.0	0.4	GO:0001056	RNA polymerase III activity(GO:0001056)
0.0	0.1	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.1	GO:0043199	sulfate binding(GO:0043199)
0.0	7.8	GO:0004674	protein serine/threonine kinase activity(GO:0004674)
0.0	1.0	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.0	0.3	GO:0005123	death receptor binding(GO:0005123)
0.0	4.0	GO:0005125	cytokine activity(GO:0005125)
0.0	31.8	GO:0003677	DNA binding(GO:0003677)
0.0	0.4	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	1.3	GO:0004896	cytokine receptor activity(GO:0004896)
0.0	3.5	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	0.8	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.5	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.7	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	0.3	GO:0015250	water channel activity(GO:0015250)
0.0	3.5	GO:0005088	Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.0	0.1	GO:0004852	uroporphyrinogen-III synthase activity(GO:0004852)
0.0	0.4	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.2	GO:0004806	triglyceride lipase activity(GO:0004806)
0.0	0.3	GO:0035250	UDP-galactosyltransferase activity(GO:0035250)
0.0	0.4	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.5	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.0	3.8	GO:0005096	GTPase activator activity(GO:0005096)
0.0	3.1	GO:0061659	ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.3	GO:0004890	GABA-A receptor activity(GO:0004890)
0.0	0.1	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	28.4	PID ATR PATHWAY	ATR signaling pathway
0.4	6.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.4	59.5	PID CMYB PATHWAY	C-MYB transcription factor network
0.4	20.7	PID AURORA B PATHWAY	Aurora B signaling
0.3	4.8	PID S1P S1P4 PATHWAY	S1P4 pathway
0.3	12.8	PID AURORA A PATHWAY	Aurora A signaling
0.3	7.2	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.3	8.9	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.2	6.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2	7.7	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.2	10.7	PID ARF6 PATHWAY	Arf6 signaling events
0.2	6.5	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.2	6.8	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.2	5.0	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.2	11.2	PID P53 REGULATION PATHWAY	p53 pathway
0.2	2.5	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.1	4.6	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.1	7.2	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.1	7.1	PID RAS PATHWAY	Regulation of Ras family activation
0.1	2.6	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.1	2.5	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.1	2.8	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.1	8.3	PID RAC1 PATHWAY	RAC1 signaling pathway
0.1	8.6	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	2.9	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.1	6.1	PID TNF PATHWAY	TNF receptor signaling pathway
0.1	2.6	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.1	6.0	PID BMP PATHWAY	BMP receptor signaling
0.1	7.5	PID IL12 2PATHWAY	IL12-mediated signaling events
0.1	3.4	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.1	1.0	PID IL27 PATHWAY	IL27-mediated signaling events
0.1	3.8	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.1	2.4	PID MYC PATHWAY	C-MYC pathway
0.1	3.3	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	3.5	PID PLK1 PATHWAY	PLK1 signaling events
0.1	1.6	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.1	2.5	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.1	5.2	PID P73PATHWAY	p73 transcription factor network
0.1	1.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.1	2.1	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.1	3.8	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.1	1.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	1.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.1	0.8	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.1	4.6	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.1	5.0	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.1	0.8	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.4	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.0	0.3	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	1.8	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	3.8	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.7	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	1.4	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	1.4	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.4	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.7	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	1.1	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	3.0	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	0.4	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.6	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.4	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.2	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.5	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.7	10.6	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
1.5	3.1	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.7	13.8	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.6	10.5	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.5	7.7	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.5	15.9	REACTOME KINESINS	Genes involved in Kinesins
0.5	4.2	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.4	24.9	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.3	12.9	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.3	5.2	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.3	7.1	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.3	10.2	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.3	2.1	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.3	3.6	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.3	4.7	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.3	3.0	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.3	6.5	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.3	31.1	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.2	24.4	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.2	6.8	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.2	4.8	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.2	5.0	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.2	14.2	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.2	6.4	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.2	6.2	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.2	3.4	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.2	3.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.2	1.8	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.2	2.3	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.2	3.8	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.2	2.9	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.2	9.4	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.2	5.0	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.2	4.1	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.2	3.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.2	4.1	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.1	22.5	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.1	3.2	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.1	4.8	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1	6.2	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	3.9	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	2.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.1	3.3	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	3.4	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1	5.2	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	5.6	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	4.8	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1	2.8	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	2.2	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1	2.0	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.1	1.4	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	1.4	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.1	3.0	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.1	0.6	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.1	1.4	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1	2.7	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1	1.8	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	2.7	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.1	0.8	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	1.3	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1	3.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	0.9	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	1.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.1	0.7	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1	2.1	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.9	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	1.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	1.6	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	2.3	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.6	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.0	1.1	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.6	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	3.3	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	1.4	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	0.3	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.8	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	1.1	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.9	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.1	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.8	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	3.2	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.6	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	2.3	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.0	0.7	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	1.8	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	1.3	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	1.3	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.3	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.2	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	1.1	REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE	Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0	0.7	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.0	0.2	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.2	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling

Results for Pitx2_Otx2

Z-value: 1.52

Motif logo

Transcription factors associated with Pitx2_Otx2

Activity-expression correlation:

Activity profile of Pitx2_Otx2 motif

Sorted Z-values of Pitx2_Otx2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Pitx2_Otx2

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: