ISMARA results: Pitx3

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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Pitx3

Z-value: 0.76

Motif logo

Transcription factors associated with Pitx3

Gene Symbol	Gene ID	Gene Info
Pitx3 Ensembl NCBI MGI UniProt	ENSMUSG00000025229.16	Pitx3

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Pitx3	mm39_v1_chr19_-_46136765_46136825	-0.10	4.2e-01	Click!

Activity profile of Pitx3 motif

Sorted Z-values of Pitx3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Pitx3

View svg image
View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr7_-_19426529 Show fit	7.62	ENSMUST00000207978.2 ENSMUST00000108451.4 ENSMUST00000045035.12	Apoc1 Ensembl NCBI MGI UniProt Show fit	apolipoprotein C-I
chr9_+_46180362 Show fit	7.25	ENSMUST00000214202.2 ENSMUST00000215458.2 ENSMUST00000215187.2 ENSMUST00000213878.2 ENSMUST00000034584.4	Apoa5 Ensembl NCBI MGI UniProt Show fit	apolipoprotein A-V
chr6_-_128503666 Show fit	6.08	ENSMUST00000143664.2 ENSMUST00000112132.8	Pzp Ensembl NCBI MGI UniProt Show fit	PZP, alpha-2-macroglobulin like
chr9_+_119186447 Show fit	5.93	ENSMUST00000039610.10	Xylb Ensembl NCBI MGI UniProt Show fit	xylulokinase homolog (H. influenzae)
chr19_+_43770619 Show fit	5.92	ENSMUST00000026208.6	Abcc2 Ensembl NCBI MGI UniProt Show fit	ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr7_+_26728499 Show fit	5.85	ENSMUST00000075552.7	Cyp2a12 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 2, subfamily a, polypeptide 12
chr10_-_127843377 Show fit	5.61	ENSMUST00000219447.2 ENSMUST00000219780.2 ENSMUST00000219707.2 ENSMUST00000219953.2 ENSMUST00000219183.2	Hsd17b6 Ensembl NCBI MGI UniProt Show fit	hydroxysteroid (17-beta) dehydrogenase 6
chr7_-_12732067 Show fit	5.52	ENSMUST00000032539.14 ENSMUST00000120903.8	Slc27a5 Ensembl NCBI MGI UniProt Show fit	solute carrier family 27 (fatty acid transporter), member 5
chr1_+_171052623 Show fit	5.44	ENSMUST00000111321.8 ENSMUST00000005824.12 ENSMUST00000111320.8 ENSMUST00000111319.2	Apoa2 Ensembl NCBI MGI UniProt Show fit	apolipoprotein A-II
chr6_-_83633064 Show fit	5.12	ENSMUST00000014686.3	Clec4f Ensembl NCBI MGI UniProt Show fit	C-type lectin domain family 4, member f
chr8_-_41668182 Show fit	4.69	ENSMUST00000034003.5	Fgl1 Ensembl NCBI MGI UniProt Show fit	fibrinogen-like protein 1
chr5_-_134485430 Show fit	4.44	ENSMUST00000200944.4 ENSMUST00000202280.4 ENSMUST00000074114.12 ENSMUST00000100654.10 ENSMUST00000100650.10 ENSMUST00000111245.9 ENSMUST00000202554.4 ENSMUST00000073161.12 ENSMUST00000100652.10 ENSMUST00000171794.9 ENSMUST00000167084.9	Gtf2ird1 Ensembl NCBI MGI UniProt Show fit	general transcription factor II I repeat domain-containing 1
chr7_-_19410749 Show fit	4.16	ENSMUST00000003074.16	Apoc2 Ensembl NCBI MGI UniProt Show fit	apolipoprotein C-II
chrX_+_59044796 Show fit	4.14	ENSMUST00000033477.5	F9 Ensembl NCBI MGI UniProt Show fit	coagulation factor IX
chr2_-_25517945 Show fit	3.96	ENSMUST00000028307.9	Fcna Ensembl NCBI MGI UniProt Show fit	ficolin A
chr17_-_32639936 Show fit	3.95	ENSMUST00000170392.9 ENSMUST00000237165.2 ENSMUST00000235892.2 ENSMUST00000114455.3	Pglyrp2 Ensembl NCBI MGI UniProt Show fit	peptidoglycan recognition protein 2
chr15_+_9335636 Show fit	3.86	ENSMUST00000072403.7	Ugt3a2 Ensembl NCBI MGI UniProt Show fit	UDP glycosyltransferases 3 family, polypeptide A2
chr11_+_69945157 Show fit	3.76	ENSMUST00000108585.9 ENSMUST00000018699.13	Asgr1 Ensembl NCBI MGI UniProt Show fit	asialoglycoprotein receptor 1
chr1_+_180878797 Show fit	3.72	ENSMUST00000036819.7	9130409I23Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 9130409I23 gene
chr17_-_12894716 Show fit	3.55	ENSMUST00000024596.10	Slc22a1 Ensembl NCBI MGI UniProt Show fit	solute carrier family 22 (organic cation transporter), member 1
chr7_+_26534730 Show fit	3.48	ENSMUST00000005685.15	Cyp2a5 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 2, subfamily a, polypeptide 5
chr7_+_26006594 Show fit	3.26	ENSMUST00000098657.5	Cyp2a4 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 2, subfamily a, polypeptide 4
chr17_+_49735386 Show fit	3.19	ENSMUST00000165390.9 ENSMUST00000024797.16	Mocs1 Ensembl NCBI MGI UniProt Show fit	molybdenum cofactor synthesis 1
chr12_-_72675624 Show fit	3.08	ENSMUST00000208039.2 ENSMUST00000207585.2	Gm4756 Ensembl NCBI MGI UniProt Show fit	predicted gene 4756
chr17_+_49735413 Show fit	3.05	ENSMUST00000173033.8	Mocs1 Ensembl NCBI MGI UniProt Show fit	molybdenum cofactor synthesis 1
chr5_-_100720063 Show fit	3.01	ENSMUST00000031264.12	Plac8 Ensembl NCBI MGI UniProt Show fit	placenta-specific 8
chr8_+_114860297 Show fit	2.93	ENSMUST00000073521.12 ENSMUST00000066514.13	Nudt7 Ensembl NCBI MGI UniProt Show fit	nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr4_+_141473983 Show fit	2.88	ENSMUST00000038161.5	Agmat Ensembl NCBI MGI UniProt Show fit	agmatine ureohydrolase (agmatinase)
chr11_-_60702081 Show fit	2.84	ENSMUST00000018744.15	Shmt1 Ensembl NCBI MGI UniProt Show fit	serine hydroxymethyltransferase 1 (soluble)
chr13_-_41373870 Show fit	2.83	ENSMUST00000021793.15	Elovl2 Ensembl NCBI MGI UniProt Show fit	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2
chr1_+_87998487 Show fit	2.82	ENSMUST00000073772.5	Ugt1a9 Ensembl NCBI MGI UniProt Show fit	UDP glucuronosyltransferase 1 family, polypeptide A9
chr11_+_87590720 Show fit	2.81	ENSMUST00000040089.5	Rnf43 Ensembl NCBI MGI UniProt Show fit	ring finger protein 43
chr11_+_98932586 Show fit	2.78	ENSMUST00000177092.8	Igfbp4 Ensembl NCBI MGI UniProt Show fit	insulin-like growth factor binding protein 4
chr8_-_3517617 Show fit	2.77	ENSMUST00000111081.10 ENSMUST00000004686.13	Pex11g Ensembl NCBI MGI UniProt Show fit	peroxisomal biogenesis factor 11 gamma
chr4_-_44066960 Show fit	2.67	ENSMUST00000173234.8 ENSMUST00000173274.2	Gne Ensembl NCBI MGI UniProt Show fit	glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr8_+_114860375 Show fit	2.66	ENSMUST00000147605.8 ENSMUST00000134593.2	Nudt7 Ensembl NCBI MGI UniProt Show fit	nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr8_+_114860342 Show fit	2.65	ENSMUST00000109109.8	Nudt7 Ensembl NCBI MGI UniProt Show fit	nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr13_-_12479804 Show fit	2.62	ENSMUST00000124888.8	Lgals8 Ensembl NCBI MGI UniProt Show fit	lectin, galactose binding, soluble 8
chr7_+_67925718 Show fit	2.60	ENSMUST00000210558.2	Fam169b Ensembl NCBI MGI UniProt Show fit	family with sequence similarity 169, member B
chr7_-_126721398 Show fit	2.53	ENSMUST00000032912.6	Qprt Ensembl NCBI MGI UniProt Show fit	quinolinate phosphoribosyltransferase
chr6_+_90527762 Show fit	2.46	ENSMUST00000130418.8 ENSMUST00000032175.11 ENSMUST00000203111.2	Aldh1l1 Ensembl NCBI MGI UniProt Show fit	aldehyde dehydrogenase 1 family, member L1
chr9_+_89936581 Show fit	2.43	ENSMUST00000143172.8 ENSMUST00000185459.2	Ctsh Ensembl NCBI MGI UniProt Show fit	cathepsin H
chr2_-_32594156 Show fit	2.41	ENSMUST00000127812.3	Fpgs Ensembl NCBI MGI UniProt Show fit	folylpolyglutamyl synthetase
chr12_-_104010690 Show fit	2.35	ENSMUST00000043915.4	Serpina12 Ensembl NCBI MGI UniProt Show fit	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
chr5_+_120651158 Show fit	2.33	ENSMUST00000111889.2	Slc8b1 Ensembl NCBI MGI UniProt Show fit	solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr10_+_62782786 Show fit	2.17	ENSMUST00000131422.8	Dna2 Ensembl NCBI MGI UniProt Show fit	DNA replication helicase/nuclease 2
chr11_-_120618052 Show fit	2.09	ENSMUST00000106148.10 ENSMUST00000026144.5	Dcxr Ensembl NCBI MGI UniProt Show fit	dicarbonyl L-xylulose reductase
chr1_-_59276252 Show fit	2.09	ENSMUST00000163058.2 ENSMUST00000160945.2 ENSMUST00000027178.13	Als2 Ensembl NCBI MGI UniProt Show fit	alsin Rho guanine nucleotide exchange factor
chr17_-_35407403 Show fit	2.07	ENSMUST00000097336.5	Lst1 Ensembl NCBI MGI UniProt Show fit	leukocyte specific transcript 1
chr18_+_51250748 Show fit	2.07	ENSMUST00000116639.4	Prr16 Ensembl NCBI MGI UniProt Show fit	proline rich 16
chrX_-_9335525 Show fit	2.06	ENSMUST00000015484.10	Cybb Ensembl NCBI MGI UniProt Show fit	cytochrome b-245, beta polypeptide
chr16_+_31241085 Show fit	2.05	ENSMUST00000089759.9	Bdh1 Ensembl NCBI MGI UniProt Show fit	3-hydroxybutyrate dehydrogenase, type 1
chr7_+_28140352 Show fit	2.05	ENSMUST00000078845.13	Gmfg Ensembl NCBI MGI UniProt Show fit	glia maturation factor, gamma
chr14_-_25928096 Show fit	2.00	ENSMUST00000185006.9	Tmem254a Ensembl NCBI MGI UniProt Show fit	transmembrane protein 254a
chr7_+_28140450 Show fit	1.99	ENSMUST00000135686.2	Gmfg Ensembl NCBI MGI UniProt Show fit	glia maturation factor, gamma
chr9_-_78396407 Show fit	1.91	ENSMUST00000154207.8	Eef1a1 Ensembl NCBI MGI UniProt Show fit	eukaryotic translation elongation factor 1 alpha 1
chr15_-_82128888 Show fit	1.88	ENSMUST00000089155.6 ENSMUST00000089157.11	Cenpm Ensembl NCBI MGI UniProt Show fit	centromere protein M
chr12_-_72675605 Show fit	1.88	ENSMUST00000222413.2	Gm4756 Ensembl NCBI MGI UniProt Show fit	predicted gene 4756
chr5_-_65585720 Show fit	1.85	ENSMUST00000131263.3	Ugdh Ensembl NCBI MGI UniProt Show fit	UDP-glucose dehydrogenase
chr7_-_126522014 Show fit	1.85	ENSMUST00000134134.3 ENSMUST00000119781.8 ENSMUST00000121612.4	Tmem219 Ensembl NCBI MGI UniProt Show fit	transmembrane protein 219
chr14_-_30740946 Show fit	1.82	ENSMUST00000228341.2	Gnl3 Ensembl NCBI MGI UniProt Show fit	guanine nucleotide binding protein-like 3 (nucleolar)
chr7_-_140680437 Show fit	1.81	ENSMUST00000210167.2 ENSMUST00000209294.2 ENSMUST00000097958.3	Sigirr Ensembl NCBI MGI UniProt Show fit	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr8_+_85628557 Show fit	1.80	ENSMUST00000067060.10 ENSMUST00000239392.2	Klf1 Ensembl NCBI MGI UniProt Show fit	Kruppel-like factor 1 (erythroid)
chr19_+_7471398 Show fit	1.79	ENSMUST00000170373.9 ENSMUST00000236308.2 ENSMUST00000235557.2	Atl3 Ensembl NCBI MGI UniProt Show fit	atlastin GTPase 3
chr6_-_71121347 Show fit	1.77	ENSMUST00000160918.8	Thnsl2 Ensembl NCBI MGI UniProt Show fit	threonine synthase-like 2 (bacterial)
chr1_-_119576347 Show fit	1.73	ENSMUST00000027632.14 ENSMUST00000187194.2	Epb41l5 Ensembl NCBI MGI UniProt Show fit	erythrocyte membrane protein band 4.1 like 5
chr11_+_117673107 Show fit	1.73	ENSMUST00000050874.14 ENSMUST00000106334.9	Tmc8 Ensembl NCBI MGI UniProt Show fit	transmembrane channel-like gene family 8
chr3_+_95226093 Show fit	1.69	ENSMUST00000139866.2	Cers2 Ensembl NCBI MGI UniProt Show fit	ceramide synthase 2
chr9_-_15217412 Show fit	1.67	ENSMUST00000216955.2 ENSMUST00000178977.9	4931406C07Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 4931406C07 gene
chr7_-_126831803 Show fit	1.67	ENSMUST00000133913.8	Septin1 Ensembl NCBI MGI UniProt Show fit	septin 1
chr11_+_101339233 Show fit	1.67	ENSMUST00000010502.13	Ifi35 Ensembl NCBI MGI UniProt Show fit	interferon-induced protein 35
chr9_+_77848556 Show fit	1.66	ENSMUST00000134072.2	Elovl5 Ensembl NCBI MGI UniProt Show fit	ELOVL family member 5, elongation of long chain fatty acids (yeast)
chr12_-_72675670 Show fit	1.64	ENSMUST00000209038.2	Gm4756 Ensembl NCBI MGI UniProt Show fit	predicted gene 4756
chr4_+_80828883 Show fit	1.63	ENSMUST00000055922.4	Lurap1l Ensembl NCBI MGI UniProt Show fit	leucine rich adaptor protein 1-like
chr9_-_7873017 Show fit	1.63	ENSMUST00000013949.15	Birc3 Ensembl NCBI MGI UniProt Show fit	baculoviral IAP repeat-containing 3
chr6_+_71470833 Show fit	1.62	ENSMUST00000064637.11 ENSMUST00000114178.8	Rnf103 Ensembl NCBI MGI UniProt Show fit	ring finger protein 103
chr8_-_71964379 Show fit	1.62	ENSMUST00000048452.6	Plvap Ensembl NCBI MGI UniProt Show fit	plasmalemma vesicle associated protein
chr1_+_58841650 Show fit	1.60	ENSMUST00000165549.8	Casp8 Ensembl NCBI MGI UniProt Show fit	caspase 8
chr15_+_59186876 Show fit	1.56	ENSMUST00000022977.14 ENSMUST00000100640.5	Sqle Ensembl NCBI MGI UniProt Show fit	squalene epoxidase
chr10_+_62896492 Show fit	1.56	ENSMUST00000219687.2 ENSMUST00000219045.2	Pbld1 Ensembl NCBI MGI UniProt Show fit	phenazine biosynthesis-like protein domain containing 1
chr6_-_71121324 Show fit	1.53	ENSMUST00000074241.9	Thnsl2 Ensembl NCBI MGI UniProt Show fit	threonine synthase-like 2 (bacterial)
chr15_-_100579813 Show fit	1.53	ENSMUST00000230572.2	Cela1 Ensembl NCBI MGI UniProt Show fit	chymotrypsin-like elastase family, member 1
chr11_+_66915969 Show fit	1.52	ENSMUST00000079077.12 ENSMUST00000061786.6	Tmem220 Ensembl NCBI MGI UniProt Show fit	transmembrane protein 220
chr11_-_106889291 Show fit	1.52	ENSMUST00000124541.8	Kpna2 Ensembl NCBI MGI UniProt Show fit	karyopherin (importin) alpha 2
chr7_-_30119227 Show fit	1.52	ENSMUST00000208740.2 ENSMUST00000075062.5	Hcst Ensembl NCBI MGI UniProt Show fit	hematopoietic cell signal transducer
chr2_-_29983618 Show fit	1.52	ENSMUST00000081838.7 ENSMUST00000102865.11	Zdhhc12 Ensembl NCBI MGI UniProt Show fit	zinc finger, DHHC domain containing 12
chr14_+_25942963 Show fit	1.50	ENSMUST00000184016.3	Cphx1 Ensembl NCBI MGI UniProt Show fit	cytoplasmic polyadenylated homeobox 1
chr2_-_85349362 Show fit	1.50	ENSMUST00000099923.2	Fads2b Ensembl NCBI MGI UniProt Show fit	fatty acid desaturase 2B
chr19_+_7471560 Show fit	1.48	ENSMUST00000237998.2	Atl3 Ensembl NCBI MGI UniProt Show fit	atlastin GTPase 3
chr18_+_34869412 Show fit	1.45	ENSMUST00000105038.3	Gm3550 Ensembl NCBI MGI UniProt Show fit	predicted gene 3550
chr15_-_58828321 Show fit	1.43	ENSMUST00000228067.2	Mtss1 Ensembl NCBI MGI UniProt Show fit	MTSS I-BAR domain containing 1
chr16_+_35758836 Show fit	1.42	ENSMUST00000114878.8	Parp9 Ensembl NCBI MGI UniProt Show fit	poly (ADP-ribose) polymerase family, member 9
chr13_-_64514830 Show fit	1.41	ENSMUST00000222971.2	Ctsl Ensembl NCBI MGI UniProt Show fit	cathepsin L
chr14_-_70585874 Show fit	1.40	ENSMUST00000152067.8	Slc39a14 Ensembl NCBI MGI UniProt Show fit	solute carrier family 39 (zinc transporter), member 14
chr2_+_32647246 Show fit	1.40	ENSMUST00000009707.14 ENSMUST00000177382.2 ENSMUST00000140999.2	Tor2a Ensembl NCBI MGI UniProt Show fit	torsin family 2, member A
chr11_-_120508713 Show fit	1.39	ENSMUST00000106188.4 ENSMUST00000026129.16	Pcyt2 Ensembl NCBI MGI UniProt Show fit	phosphate cytidylyltransferase 2, ethanolamine
chr8_+_70583971 Show fit	1.36	ENSMUST00000211898.2 ENSMUST00000095273.7	Nr2c2ap Ensembl NCBI MGI UniProt Show fit	nuclear receptor 2C2-associated protein
chr19_+_44980565 Show fit	1.35	ENSMUST00000179305.2	Sema4g Ensembl NCBI MGI UniProt Show fit	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr14_+_74973081 Show fit	1.35	ENSMUST00000177283.8	Esd Ensembl NCBI MGI UniProt Show fit	esterase D/formylglutathione hydrolase
chr11_-_106890195 Show fit	1.34	ENSMUST00000106768.2 ENSMUST00000144834.8	Kpna2 Ensembl NCBI MGI UniProt Show fit	karyopherin (importin) alpha 2
chr11_-_100026754 Show fit	1.34	ENSMUST00000107411.3	Krt15 Ensembl NCBI MGI UniProt Show fit	keratin 15
chrX_-_137985960 Show fit	1.32	ENSMUST00000033626.15 ENSMUST00000060824.4	Serpina7 Ensembl NCBI MGI UniProt Show fit	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr9_+_114560235 Show fit	1.30	ENSMUST00000035007.10	Cmtm6 Ensembl NCBI MGI UniProt Show fit	CKLF-like MARVEL transmembrane domain containing 6
chr7_-_84328553 Show fit	1.29	ENSMUST00000069537.3 ENSMUST00000207865.2 ENSMUST00000178385.9 ENSMUST00000208782.2	Zfand6 Ensembl NCBI MGI UniProt Show fit	zinc finger, AN1-type domain 6
chr4_+_135639117 Show fit	1.27	ENSMUST00000068830.4	Cnr2 Ensembl NCBI MGI UniProt Show fit	cannabinoid receptor 2 (macrophage)
chr3_-_88363704 Show fit	1.27	ENSMUST00000141471.2 ENSMUST00000123753.8	Sema4a Ensembl NCBI MGI UniProt Show fit	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr8_-_72966663 Show fit	1.26	ENSMUST00000098630.5	Cib3 Ensembl NCBI MGI UniProt Show fit	calcium and integrin binding family member 3
chr9_-_7873171 Show fit	1.26	ENSMUST00000159323.2 ENSMUST00000115673.3	Birc3 Ensembl NCBI MGI UniProt Show fit	baculoviral IAP repeat-containing 3
chr7_-_28079678 Show fit	1.26	ENSMUST00000051241.7	Zfp36 Ensembl NCBI MGI UniProt Show fit	zinc finger protein 36
chrX_-_161671421 Show fit	1.25	ENSMUST00000033723.4	Syap1 Ensembl NCBI MGI UniProt Show fit	synapse associated protein 1
chr15_+_102391614 Show fit	1.24	ENSMUST00000229432.2	Pcbp2 Ensembl NCBI MGI UniProt Show fit	poly(rC) binding protein 2
chr14_-_59632830 Show fit	1.24	ENSMUST00000166912.3	Phf11c Ensembl NCBI MGI UniProt Show fit	PHD finger protein 11C
chr11_+_117672902 Show fit	1.22	ENSMUST00000127080.9	Tmc8 Ensembl NCBI MGI UniProt Show fit	transmembrane channel-like gene family 8
chrX_+_35375751 Show fit	1.21	ENSMUST00000033418.8	Il13ra1 Ensembl NCBI MGI UniProt Show fit	interleukin 13 receptor, alpha 1
chr3_-_96721829 Show fit	1.20	ENSMUST00000047702.8	Cd160 Ensembl NCBI MGI UniProt Show fit	CD160 antigen
chr6_+_34331054 Show fit	1.20	ENSMUST00000038406.7	Akr1b8 Ensembl NCBI MGI UniProt Show fit	aldo-keto reductase family 1, member B8
chr3_-_88363027 Show fit	1.19	ENSMUST00000029700.12	Sema4a Ensembl NCBI MGI UniProt Show fit	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr3_-_88362999 Show fit	1.19	ENSMUST00000107531.8	Sema4a Ensembl NCBI MGI UniProt Show fit	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr19_+_8861096 Show fit	1.19	ENSMUST00000187504.7	Lbhd1 Ensembl NCBI MGI UniProt Show fit	LBH domain containing 1
chr11_-_106890307 Show fit	1.19	ENSMUST00000018506.13	Kpna2 Ensembl NCBI MGI UniProt Show fit	karyopherin (importin) alpha 2
chr19_+_3991522 Show fit	1.17	ENSMUST00000237030.2	Unc93b1 Ensembl NCBI MGI UniProt Show fit	unc-93 homolog B1, TLR signaling regulator
chr11_-_117673008 Show fit	1.17	ENSMUST00000152304.3	Tmc6 Ensembl NCBI MGI UniProt Show fit	transmembrane channel-like gene family 6
chr7_+_19197192 Show fit	1.16	ENSMUST00000137613.9	Exoc3l2 Ensembl NCBI MGI UniProt Show fit	exocyst complex component 3-like 2
chr2_+_24276545 Show fit	1.15	ENSMUST00000127242.2	Psd4 Ensembl NCBI MGI UniProt Show fit	pleckstrin and Sec7 domain containing 4
chr4_-_129155185 Show fit	1.13	ENSMUST00000145261.8	C77080 Ensembl NCBI MGI UniProt Show fit	expressed sequence C77080
chr5_-_125371162 Show fit	1.12	ENSMUST00000127148.2	Scarb1 Ensembl NCBI MGI UniProt Show fit	scavenger receptor class B, member 1
chr8_+_34143266 Show fit	1.12	ENSMUST00000033992.9	Gsr Ensembl NCBI MGI UniProt Show fit	glutathione reductase
chr5_+_34683141 Show fit	1.12	ENSMUST00000125817.8 ENSMUST00000067638.14	Sh3bp2 Ensembl NCBI MGI UniProt Show fit	SH3-domain binding protein 2
chr14_+_54380308 Show fit	1.11	ENSMUST00000196323.2	Trdc Ensembl NCBI MGI UniProt Show fit	T cell receptor delta, constant region
chr14_+_31888061 Show fit	1.10	ENSMUST00000164341.2	Ncoa4 Ensembl NCBI MGI UniProt Show fit	nuclear receptor coactivator 4
chr5_+_66018555 Show fit	1.10	ENSMUST00000031106.8	Rhoh Ensembl NCBI MGI UniProt Show fit	ras homolog family member H
chr4_+_155646807 Show fit	1.09	ENSMUST00000030939.14	Nadk Ensembl NCBI MGI UniProt Show fit	NAD kinase
chr6_+_86605146 Show fit	1.08	ENSMUST00000043400.9	Asprv1 Ensembl NCBI MGI UniProt Show fit	aspartic peptidase, retroviral-like 1
chr9_-_70328816 Show fit	1.08	ENSMUST00000034742.8	Ccnb2 Ensembl NCBI MGI UniProt Show fit	cyclin B2
chr1_-_131172903 Show fit	1.07	ENSMUST00000027688.15 ENSMUST00000112442.2	Rassf5 Ensembl NCBI MGI UniProt Show fit	Ras association (RalGDS/AF-6) domain family member 5
chr16_-_93400691 Show fit	1.06	ENSMUST00000023669.14 ENSMUST00000233931.2 ENSMUST00000154355.3	Setd4 Ensembl NCBI MGI UniProt Show fit	SET domain containing 4
chr13_-_120677483 Show fit	1.05	ENSMUST00000225881.2	Gm21762 Ensembl NCBI MGI UniProt Show fit	predicted gene, 21762
chr14_+_54433095 Show fit	1.05	ENSMUST00000103717.3	Traj24 Ensembl NCBI MGI UniProt Show fit	T cell receptor alpha joining 24
chr8_-_23680954 Show fit	1.04	ENSMUST00000209507.2	Gpat4 Ensembl NCBI MGI UniProt Show fit	glycerol-3-phosphate acyltransferase 4
chr3_+_89979948 Show fit	1.04	ENSMUST00000121503.8 ENSMUST00000119570.8	Tpm3 Ensembl NCBI MGI UniProt Show fit	tropomyosin 3, gamma
chr11_-_46581135 Show fit	1.03	ENSMUST00000169584.8	Timd2 Ensembl NCBI MGI UniProt Show fit	T cell immunoglobulin and mucin domain containing 2
chr11_+_114559350 Show fit	1.02	ENSMUST00000106602.10 ENSMUST00000077915.10 ENSMUST00000106599.8 ENSMUST00000082092.5	Rpl38 Ensembl NCBI MGI UniProt Show fit	ribosomal protein L38
chr9_+_69305180 Show fit	1.02	ENSMUST00000034761.15 ENSMUST00000125938.2	Ice2 Ensembl NCBI MGI UniProt Show fit	interactor of little elongation complex ELL subunit 2
chr5_+_115697526 Show fit	1.01	ENSMUST00000086519.12 ENSMUST00000156359.2 ENSMUST00000152976.2	Rplp0 Ensembl NCBI MGI UniProt Show fit	ribosomal protein, large, P0
chr11_+_96920751 Show fit	1.01	ENSMUST00000021249.11	Scrn2 Ensembl NCBI MGI UniProt Show fit	secernin 2
chr11_-_6470918 Show fit	0.99	ENSMUST00000003459.4	Myo1g Ensembl NCBI MGI UniProt Show fit	myosin IG
chr1_+_85538554 Show fit	0.99	ENSMUST00000162925.2	Sp140 Ensembl NCBI MGI UniProt Show fit	Sp140 nuclear body protein
chr7_-_100164007 Show fit	0.99	ENSMUST00000207405.2	Dnajb13 Ensembl NCBI MGI UniProt Show fit	DnaJ heat shock protein family (Hsp40) member B13
chr3_-_146227144 Show fit	0.99	ENSMUST00000199079.2 ENSMUST00000029838.11	Rpf1 Ensembl NCBI MGI UniProt Show fit	ribosome production factor 1 homolog
chr15_+_99290763 Show fit	0.99	ENSMUST00000023749.15	Tmbim6 Ensembl NCBI MGI UniProt Show fit	transmembrane BAX inhibitor motif containing 6
chr6_+_42326528 Show fit	0.98	ENSMUST00000203329.3	Zyx Ensembl NCBI MGI UniProt Show fit	zyxin
chr17_+_24888641 Show fit	0.98	ENSMUST00000234956.2	Zfp598 Ensembl NCBI MGI UniProt Show fit	zinc finger protein 598
chr5_-_134485081 Show fit	0.97	ENSMUST00000111244.5	Gtf2ird1 Ensembl NCBI MGI UniProt Show fit	general transcription factor II I repeat domain-containing 1
chr8_+_71995554 Show fit	0.96	ENSMUST00000034272.9	Mvb12a Ensembl NCBI MGI UniProt Show fit	multivesicular body subunit 12A
chr7_-_44753168 Show fit	0.94	ENSMUST00000211085.2 ENSMUST00000210642.2 ENSMUST00000003512.9	Fcgrt Ensembl NCBI MGI UniProt Show fit	Fc fragment of IgG receptor and transporter
chr1_+_85503397 Show fit	0.94	ENSMUST00000178024.2	G530012D18Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA G530012D1 gene
chr1_+_134038970 Show fit	0.94	ENSMUST00000159963.8 ENSMUST00000160060.8	Chit1 Ensembl NCBI MGI UniProt Show fit	chitinase 1 (chitotriosidase)
chr5_+_108048367 Show fit	0.94	ENSMUST00000082223.13	Rpl5 Ensembl NCBI MGI UniProt Show fit	ribosomal protein L5
chr7_-_101234800 Show fit	0.93	ENSMUST00000209526.2	Art2b Ensembl NCBI MGI UniProt Show fit	ADP-ribosyltransferase 2b
chr5_-_136003294 Show fit	0.93	ENSMUST00000154181.2 ENSMUST00000111152.8 ENSMUST00000111153.8	Ssc4d Ensembl NCBI MGI UniProt Show fit	scavenger receptor cysteine rich family, 4 domains
chr14_-_86986541 Show fit	0.92	ENSMUST00000226254.2	Diaph3 Ensembl NCBI MGI UniProt Show fit	diaphanous related formin 3
chr18_-_3309858 Show fit	0.92	ENSMUST00000144496.8 ENSMUST00000154715.8	Crem Ensembl NCBI MGI UniProt Show fit	cAMP responsive element modulator
chr7_-_98829474 Show fit	0.92	ENSMUST00000207611.2	Dgat2 Ensembl NCBI MGI UniProt Show fit	diacylglycerol O-acyltransferase 2
chr19_+_6111204 Show fit	0.91	ENSMUST00000162726.5	Znhit2 Ensembl NCBI MGI UniProt Show fit	zinc finger, HIT domain containing 2
chr14_+_47710005 Show fit	0.91	ENSMUST00000043112.9 ENSMUST00000163324.8 ENSMUST00000228668.2 ENSMUST00000168833.9	Fbxo34 Ensembl NCBI MGI UniProt Show fit	F-box protein 34
chr11_-_120687195 Show fit	0.90	ENSMUST00000143139.8 ENSMUST00000129955.2 ENSMUST00000026151.11 ENSMUST00000167023.8 ENSMUST00000106133.8 ENSMUST00000106135.8	Dus1l Ensembl NCBI MGI UniProt Show fit	dihydrouridine synthase 1-like (S. cerevisiae)
chr6_+_41510925 Show fit	0.90	ENSMUST00000103285.2	Trbj1-2 Ensembl NCBI MGI UniProt Show fit	T cell receptor beta joining 1-2
chr6_+_122803624 Show fit	0.89	ENSMUST00000203075.2	Foxj2 Ensembl NCBI MGI UniProt Show fit	forkhead box J2
chr18_-_74340842 Show fit	0.89	ENSMUST00000040188.16	Ska1 Ensembl NCBI MGI UniProt Show fit	spindle and kinetochore associated complex subunit 1
chr1_+_92900834 Show fit	0.89	ENSMUST00000186298.7 ENSMUST00000027489.9	Gpr35 Ensembl NCBI MGI UniProt Show fit	G protein-coupled receptor 35
chr2_+_79538124 Show fit	0.89	ENSMUST00000090760.9 ENSMUST00000040863.11 ENSMUST00000111780.3	Ppp1r1c Ensembl NCBI MGI UniProt Show fit	protein phosphatase 1, regulatory inhibitor subunit 1C
chr7_-_66038033 Show fit	0.88	ENSMUST00000015277.14	Lrrk1 Ensembl NCBI MGI UniProt Show fit	leucine-rich repeat kinase 1
chr1_-_134289670 Show fit	0.88	ENSMUST00000049470.11	Tmem183a Ensembl NCBI MGI UniProt Show fit	transmembrane protein 183A
chr12_-_69205882 Show fit	0.88	ENSMUST00000037023.9	Rps29 Ensembl NCBI MGI UniProt Show fit	ribosomal protein S29
chr18_-_10610332 Show fit	0.88	ENSMUST00000025142.13	Esco1 Ensembl NCBI MGI UniProt Show fit	establishment of sister chromatid cohesion N-acetyltransferase 1
chr15_-_82128538 Show fit	0.87	ENSMUST00000229747.2 ENSMUST00000230408.2	Cenpm Ensembl NCBI MGI UniProt Show fit	centromere protein M
chr1_-_159981132 Show fit	0.87	ENSMUST00000039178.12	Tnn Ensembl NCBI MGI UniProt Show fit	tenascin N
chr7_-_126391657 Show fit	0.87	ENSMUST00000032936.8	Ppp4c Ensembl NCBI MGI UniProt Show fit	protein phosphatase 4, catalytic subunit
chr7_-_26928029 Show fit	0.86	ENSMUST00000003850.8	Itpkc Ensembl NCBI MGI UniProt Show fit	inositol 1,4,5-trisphosphate 3-kinase C
chr17_+_24888704 Show fit	0.86	ENSMUST00000047179.7	Zfp598 Ensembl NCBI MGI UniProt Show fit	zinc finger protein 598
chr15_+_8138757 Show fit	0.85	ENSMUST00000163765.3	Nup155 Ensembl NCBI MGI UniProt Show fit	nucleoporin 155
chr12_-_113392174 Show fit	0.85	ENSMUST00000103427.2	Ighj4 Ensembl NCBI MGI UniProt Show fit	immunoglobulin heavy joining 4
chr15_+_99290832 Show fit	0.84	ENSMUST00000160635.8 ENSMUST00000161250.8 ENSMUST00000229392.2 ENSMUST00000161778.8	Tmbim6 Ensembl NCBI MGI UniProt Show fit	transmembrane BAX inhibitor motif containing 6
chr13_+_120306884 Show fit	0.84	ENSMUST00000195797.2	D13Ertd608e Ensembl NCBI MGI UniProt Show fit	DNA segment, Chr 13, ERATO Doi 608, expressed
chr3_-_105839980 Show fit	0.84	ENSMUST00000098758.5	I830077J02Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA I830077J02 gene
chr6_+_125048230 Show fit	0.83	ENSMUST00000140346.9 ENSMUST00000171989.3	Lpar5 Ensembl NCBI MGI UniProt Show fit	lysophosphatidic acid receptor 5
chr1_-_184615415 Show fit	0.82	ENSMUST00000048308.6	C130074G19Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA C130074G19 gene
chr4_+_155666933 Show fit	0.82	ENSMUST00000105612.2	Nadk Ensembl NCBI MGI UniProt Show fit	NAD kinase
chr8_+_47246534 Show fit	0.82	ENSMUST00000210218.2	Irf2 Ensembl NCBI MGI UniProt Show fit	interferon regulatory factor 2
chr11_+_54757200 Show fit	0.82	ENSMUST00000020504.6	Hint1 Ensembl NCBI MGI UniProt Show fit	histidine triad nucleotide binding protein 1
chr11_-_115024807 Show fit	0.82	ENSMUST00000106561.8 ENSMUST00000051264.14 ENSMUST00000106562.3	Cd300lf Ensembl NCBI MGI UniProt Show fit	CD300 molecule like family member F
chr2_-_32594043 Show fit	0.82	ENSMUST00000143743.2	Fpgs Ensembl NCBI MGI UniProt Show fit	folylpolyglutamyl synthetase
chr16_+_38383182 Show fit	0.81	ENSMUST00000163948.8	Tmem39a Ensembl NCBI MGI UniProt Show fit	transmembrane protein 39a
chr11_-_100661762 Show fit	0.81	ENSMUST00000139341.2 ENSMUST00000017891.14	Ghdc Ensembl NCBI MGI UniProt Show fit	GH3 domain containing
chr6_+_65019574 Show fit	0.81	ENSMUST00000031984.9 ENSMUST00000205118.3	Smarcad1 Ensembl NCBI MGI UniProt Show fit	SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr11_-_93856783 Show fit	0.81	ENSMUST00000021220.10	Nme1 Ensembl NCBI MGI UniProt Show fit	NME/NM23 nucleoside diphosphate kinase 1
chr5_-_127694436 Show fit	0.81	ENSMUST00000031367.15	Slc15a4 Ensembl NCBI MGI UniProt Show fit	solute carrier family 15, member 4
chr3_-_36626101 Show fit	0.81	ENSMUST00000029270.10	Ccna2 Ensembl NCBI MGI UniProt Show fit	cyclin A2
chr1_+_118249558 Show fit	0.81	ENSMUST00000027626.13 ENSMUST00000112688.10	Nifk Ensembl NCBI MGI UniProt Show fit	nucleolar protein interacting with the FHA domain of MKI67
chr2_+_167774247 Show fit	0.80	ENSMUST00000029053.8	Ptpn1 Ensembl NCBI MGI UniProt Show fit	protein tyrosine phosphatase, non-receptor type 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.2	12.7	GO:0010901	regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
2.7	8.0	GO:0042732	D-xylose metabolic process(GO:0042732)
2.1	8.2	GO:0034034	coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
1.4	5.5	GO:0046951	ketone body biosynthetic process(GO:0046951)
1.3	4.0	GO:0071846	actin filament debranching(GO:0071846)
1.2	5.9	GO:0050787	detoxification of mercury ion(GO:0050787)
1.1	5.4	GO:0014886	transition between slow and fast fiber(GO:0014886)
1.1	3.2	GO:0046901	tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
1.0	4.2	GO:0060697	positive regulation of phospholipid catabolic process(GO:0060697)
0.9	2.8	GO:0019264	glycine biosynthetic process from serine(GO:0019264)
0.9	2.8	GO:0038018	Wnt receptor catabolic process(GO:0038018)
0.8	2.5	GO:0009397	10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.8	2.4	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.8	2.4	GO:0007509	mesoderm migration involved in gastrulation(GO:0007509)
0.8	6.2	GO:0006777	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.7	2.0	GO:0033189	response to vitamin A(GO:0033189)
0.7	3.3	GO:0006566	threonine metabolic process(GO:0006566)
0.7	4.0	GO:0032827	negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.6	3.3	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.6	2.8	GO:0044375	regulation of peroxisome size(GO:0044375)
0.5	2.2	GO:1902990	mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.5	1.6	GO:0060392	negative regulation of SMAD protein import into nucleus(GO:0060392)
0.5	2.0	GO:0035963	response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.5	2.8	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.5	1.4	GO:0046294	formaldehyde catabolic process(GO:0046294)
0.4	15.3	GO:0080184	response to phenylpropanoid(GO:0080184)
0.4	1.7	GO:1903976	negative regulation of glial cell migration(GO:1903976)
0.4	1.3	GO:1904582	positive regulation of intracellular mRNA localization(GO:1904582)
0.4	1.2	GO:0006714	sesquiterpenoid metabolic process(GO:0006714)
0.4	1.2	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.4	3.5	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.4	2.6	GO:0002317	plasma cell differentiation(GO:0002317)
0.4	1.1	GO:0015920	lipopolysaccharide transport(GO:0015920)
0.4	4.5	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.4	1.8	GO:1904721	regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.3	1.3	GO:0038096	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.3	0.3	GO:0016561	protein import into peroxisome matrix, translocation(GO:0016561)
0.3	0.9	GO:1903632	positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.3	2.2	GO:0060309	elastin catabolic process(GO:0060309)
0.3	0.9	GO:0034201	response to oleic acid(GO:0034201)
0.3	4.0	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.3	0.9	GO:1904456	negative regulation of neuronal action potential(GO:1904456)
0.3	1.4	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.3	1.8	GO:0072344	rescue of stalled ribosome(GO:0072344)
0.3	2.1	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.3	1.0	GO:0002071	glandular epithelial cell maturation(GO:0002071)
0.3	5.1	GO:0051132	NK T cell activation(GO:0051132)
0.2	1.0	GO:1904158	axonemal central apparatus assembly(GO:1904158)
0.2	0.7	GO:0098974	postsynaptic actin cytoskeleton organization(GO:0098974)
0.2	1.9	GO:0006741	NADP biosynthetic process(GO:0006741)
0.2	1.4	GO:0034334	adherens junction maintenance(GO:0034334)
0.2	0.7	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.2	2.8	GO:0052697	flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.2	0.7	GO:0002625	regulation of T cell antigen processing and presentation(GO:0002625)
0.2	1.6	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.2	0.5	GO:0002884	negative regulation of hypersensitivity(GO:0002884)
0.2	0.7	GO:1904826	regulation of hydrogen sulfide biosynthetic process(GO:1904826) positive regulation of hydrogen sulfide biosynthetic process(GO:1904828)
0.2	1.5	GO:1903772	regulation of viral budding via host ESCRT complex(GO:1903772)
0.2	0.9	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.2	0.9	GO:0036228	protein targeting to nuclear inner membrane(GO:0036228)
0.2	0.6	GO:0030961	peptidyl-arginine hydroxylation(GO:0030961)
0.2	0.6	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.2	0.6	GO:0070563	negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.2	0.8	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.2	1.2	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.2	5.9	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.2	0.8	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.2	0.8	GO:1900110	negative regulation of histone H3-K9 dimethylation(GO:1900110)
0.2	0.6	GO:0045590	negative regulation of regulatory T cell differentiation(GO:0045590)
0.2	0.7	GO:0017126	nucleologenesis(GO:0017126)
0.2	0.6	GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.2	0.6	GO:0002426	immunoglobulin production in mucosal tissue(GO:0002426)
0.2	3.9	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.2	0.6	GO:0006667	sphinganine metabolic process(GO:0006667)
0.2	0.9	GO:0034421	post-translational protein acetylation(GO:0034421)
0.2	0.7	GO:0090646	mitochondrial tRNA processing(GO:0090646)
0.2	0.6	GO:2000521	negative regulation of immunological synapse formation(GO:2000521) regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001188) negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001189)
0.2	1.6	GO:0036462	TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.2	2.5	GO:0060330	regulation of response to interferon-gamma(GO:0060330)
0.2	0.6	GO:0042335	cuticle development(GO:0042335)
0.1	4.0	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.1	1.3	GO:0048318	axial mesoderm development(GO:0048318)
0.1	0.7	GO:1904715	negative regulation of chaperone-mediated autophagy(GO:1904715)
0.1	0.7	GO:1901837	negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.1	2.4	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.1	1.2	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.1	2.8	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1	0.4	GO:1905223	epicardium morphogenesis(GO:1905223)
0.1	0.6	GO:0034727	lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521) amino acid homeostasis(GO:0080144) negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis(GO:0090157)
0.1	0.4	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
0.1	0.4	GO:0015891	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1	2.7	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.1	0.8	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1	0.6	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.1	0.8	GO:0015817	histidine transport(GO:0015817)
0.1	3.9	GO:0032460	negative regulation of protein oligomerization(GO:0032460)
0.1	0.5	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1	0.5	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1	0.4	GO:0034769	basement membrane disassembly(GO:0034769)
0.1	1.3	GO:0045759	negative regulation of action potential(GO:0045759)
0.1	0.4	GO:0045004	leading strand elongation(GO:0006272) DNA replication proofreading(GO:0045004)
0.1	2.3	GO:0006851	mitochondrial calcium ion transport(GO:0006851)
0.1	0.4	GO:0046100	GMP catabolic process(GO:0046038) hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.1	0.5	GO:0000915	assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1	0.6	GO:0070934	interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549) CRD-mediated mRNA stabilization(GO:0070934)
0.1	1.5	GO:0006228	UTP biosynthetic process(GO:0006228)
0.1	2.6	GO:1904814	regulation of protein localization to chromosome, telomeric region(GO:1904814)
0.1	0.8	GO:0016259	selenocysteine metabolic process(GO:0016259)
0.1	1.8	GO:0043249	erythrocyte maturation(GO:0043249)
0.1	0.4	GO:0002752	cell surface pattern recognition receptor signaling pathway(GO:0002752) positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.1	3.7	GO:0045063	T-helper 1 cell differentiation(GO:0045063)
0.1	0.9	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1	1.8	GO:0051601	exocyst localization(GO:0051601)
0.1	1.6	GO:0070933	histone H4 deacetylation(GO:0070933)
0.1	0.5	GO:1901355	response to rapamycin(GO:1901355)
0.1	0.4	GO:0030450	regulation of complement activation, classical pathway(GO:0030450)
0.1	3.0	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.1	1.0	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.1	0.7	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.1	0.8	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
0.1	0.4	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
0.1	0.3	GO:0071348	cellular response to interleukin-11(GO:0071348)
0.1	1.5	GO:0006622	protein targeting to lysosome(GO:0006622)
0.1	1.1	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.1	1.0	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.1	0.2	GO:0046490	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.1	0.3	GO:0008594	photoreceptor cell morphogenesis(GO:0008594)
0.1	1.4	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1	6.0	GO:0007566	embryo implantation(GO:0007566)
0.1	0.1	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1	1.0	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.1	1.4	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.1	0.7	GO:0060613	fat pad development(GO:0060613)
0.1	1.3	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.1	0.8	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.1	0.8	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.1	0.3	GO:0034227	tRNA thio-modification(GO:0034227)
0.1	0.8	GO:0051084	'de novo' posttranslational protein folding(GO:0051084)
0.1	0.2	GO:0006788	heme oxidation(GO:0006788)
0.1	0.8	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1	0.1	GO:0060734	regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.1	0.6	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.1	1.6	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.1	0.1	GO:0070104	negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.1	0.5	GO:0032790	ribosome disassembly(GO:0032790)
0.1	0.2	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1	0.3	GO:0000963	mitochondrial RNA processing(GO:0000963)
0.1	0.3	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1	8.9	GO:0008203	cholesterol metabolic process(GO:0008203)
0.1	1.5	GO:0045793	positive regulation of cell size(GO:0045793)
0.1	1.3	GO:0043574	protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.1	0.4	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	1.0	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0	3.3	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.0	1.5	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.0	0.4	GO:0006983	ER overload response(GO:0006983)
0.0	1.2	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.0	0.2	GO:0071475	cellular hyperosmotic salinity response(GO:0071475)
0.0	1.5	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.7	GO:0071294	cellular response to zinc ion(GO:0071294)
0.0	0.2	GO:0036015	response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0	0.2	GO:1990481	mRNA pseudouridine synthesis(GO:1990481)
0.0	0.2	GO:0019853	L-ascorbic acid biosynthetic process(GO:0019853)
0.0	0.1	GO:0070949	regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949)
0.0	1.9	GO:1903427	negative regulation of reactive oxygen species biosynthetic process(GO:1903427)
0.0	0.3	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0	0.5	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.2	GO:0031022	nuclear migration along microfilament(GO:0031022)
0.0	0.8	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.8	GO:0032793	positive regulation of CREB transcription factor activity(GO:0032793)
0.0	0.1	GO:0045643	regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0	2.1	GO:0007032	endosome organization(GO:0007032)
0.0	0.8	GO:0036035	osteoclast development(GO:0036035)
0.0	0.4	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.0	0.2	GO:0000821	regulation of arginine metabolic process(GO:0000821)
0.0	0.5	GO:0060576	intestinal epithelial cell development(GO:0060576)
0.0	0.3	GO:0070475	rRNA base methylation(GO:0070475)
0.0	0.3	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.5	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.1	GO:0051030	snRNA transport(GO:0051030)
0.0	0.7	GO:0070498	interleukin-1-mediated signaling pathway(GO:0070498)
0.0	0.6	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	0.3	GO:0035878	nail development(GO:0035878)
0.0	0.2	GO:0072737	response to diamide(GO:0072737) cellular response to diamide(GO:0072738) cellular response to sodium arsenite(GO:1903936)
0.0	0.3	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0	0.6	GO:1990403	embryonic brain development(GO:1990403)
0.0	0.3	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.2	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.1	GO:0042695	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0	0.1	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0	0.5	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.0	1.0	GO:0097286	iron ion import(GO:0097286)
0.0	0.9	GO:0010569	regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0	0.1	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
0.0	0.4	GO:0072502	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0	1.8	GO:0006024	glycosaminoglycan biosynthetic process(GO:0006024)
0.0	0.1	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0	0.2	GO:1901162	serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0	0.1	GO:0071047	U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.0	0.1	GO:0006780	uroporphyrinogen III biosynthetic process(GO:0006780)
0.0	0.4	GO:0030432	peristalsis(GO:0030432)
0.0	0.1	GO:2000359	regulation of binding of sperm to zona pellucida(GO:2000359)
0.0	0.8	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.0	0.1	GO:0009313	ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.0	0.2	GO:0030242	pexophagy(GO:0030242)
0.0	0.2	GO:0090070	positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0	0.3	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0	0.2	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.2	GO:0070317	negative regulation of G0 to G1 transition(GO:0070317)
0.0	0.8	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0	0.5	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	1.2	GO:0050919	negative chemotaxis(GO:0050919)
0.0	0.2	GO:0002051	osteoblast fate commitment(GO:0002051)
0.0	0.1	GO:0009597	detection of virus(GO:0009597)
0.0	0.4	GO:0070986	left/right axis specification(GO:0070986)
0.0	1.6	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0	0.7	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.5	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.2	GO:0018344	protein geranylgeranylation(GO:0018344)
0.0	0.1	GO:0034241	positive regulation of macrophage fusion(GO:0034241)
0.0	0.6	GO:0071539	protein localization to centrosome(GO:0071539)
0.0	1.6	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.0	0.3	GO:0035067	negative regulation of histone acetylation(GO:0035067)
0.0	0.3	GO:0002230	positive regulation of defense response to virus by host(GO:0002230)
0.0	0.4	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.9	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0	3.8	GO:0008202	steroid metabolic process(GO:0008202)
0.0	0.2	GO:0015747	urate transport(GO:0015747)
0.0	0.4	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0	0.2	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.5	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0	0.3	GO:1903504	regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.1	GO:0072592	oxygen metabolic process(GO:0072592)
0.0	1.1	GO:0006749	glutathione metabolic process(GO:0006749)
0.0	0.7	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.0	0.0	GO:1903862	positive regulation of oxidative phosphorylation(GO:1903862)
0.0	1.7	GO:0030038	contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0	0.7	GO:0001541	ovarian follicle development(GO:0001541)
0.0	0.0	GO:1990167	protein K27-linked deubiquitination(GO:1990167)
0.0	0.6	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:0070861	regulation of protein exit from endoplasmic reticulum(GO:0070861)
0.0	1.3	GO:0050715	positive regulation of cytokine secretion(GO:0050715)
0.0	0.3	GO:0003334	keratinocyte development(GO:0003334)
0.0	1.7	GO:0006958	complement activation, classical pathway(GO:0006958)
0.0	1.4	GO:0031638	zymogen activation(GO:0031638)
0.0	0.0	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0	1.9	GO:0050670	regulation of lymphocyte proliferation(GO:0050670)
0.0	0.1	GO:0044821	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.1	6.2	GO:0019008	molybdopterin synthase complex(GO:0019008)
0.8	24.5	GO:0034385	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.7	2.2	GO:0005760	gamma DNA polymerase complex(GO:0005760)
0.4	1.7	GO:0097447	dendritic tree(GO:0097447)
0.4	2.0	GO:0035363	histone locus body(GO:0035363)
0.3	1.0	GO:0070992	translation initiation complex(GO:0070992)
0.3	5.9	GO:0046581	intercellular canaliculus(GO:0046581)
0.3	1.6	GO:0030690	Noc1p-Noc2p complex(GO:0030690)
0.2	2.4	GO:0097208	alveolar lamellar body(GO:0097208)
0.2	0.6	GO:0035068	micro-ribonucleoprotein complex(GO:0035068)
0.2	0.8	GO:1990578	perinuclear endoplasmic reticulum membrane(GO:1990578)
0.2	0.6	GO:0000814	ESCRT II complex(GO:0000814)
0.2	0.6	GO:0000438	core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.1	2.1	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	0.9	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.1	2.3	GO:0030061	mitochondrial crista(GO:0030061)
0.1	0.9	GO:0044611	nuclear pore inner ring(GO:0044611)
0.1	0.8	GO:0072557	IPAF inflammasome complex(GO:0072557)
0.1	0.8	GO:0097443	sorting endosome(GO:0097443)
0.1	1.3	GO:0070578	RISC-loading complex(GO:0070578)
0.1	0.6	GO:0035339	SPOTS complex(GO:0035339)
0.1	1.5	GO:0044754	autolysosome(GO:0044754)
0.1	2.8	GO:0005779	integral component of peroxisomal membrane(GO:0005779)
0.1	0.6	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1	2.8	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.1	0.8	GO:0097255	R2TP complex(GO:0097255)
0.1	1.4	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
0.1	1.0	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.1	0.4	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
0.1	1.8	GO:0000145	exocyst(GO:0000145)
0.1	0.4	GO:0033553	rDNA heterochromatin(GO:0033553)
0.1	1.0	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.1	1.0	GO:0000813	ESCRT I complex(GO:0000813)
0.1	2.2	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.1	0.1	GO:1990429	Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1	0.8	GO:0001940	male pronucleus(GO:0001940)
0.1	0.9	GO:0032009	early phagosome(GO:0032009)
0.1	0.9	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.1	0.4	GO:1990923	PET complex(GO:1990923)
0.1	10.6	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.1	0.7	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.1	0.6	GO:0070187	telosome(GO:0070187)
0.1	3.2	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.1	0.8	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.2	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.3	GO:0005610	laminin-5 complex(GO:0005610)
0.0	0.5	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	4.3	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.6	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	1.1	GO:0001891	phagocytic cup(GO:0001891)
0.0	1.4	GO:0002102	podosome(GO:0002102)
0.0	3.9	GO:0005643	nuclear pore(GO:0005643)
0.0	0.9	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.8	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.5	GO:0031415	NatA complex(GO:0031415)
0.0	0.2	GO:0043564	Ku70:Ku80 complex(GO:0043564)
0.0	0.4	GO:0045098	type III intermediate filament(GO:0045098)
0.0	0.6	GO:0031932	TORC2 complex(GO:0031932)
0.0	1.1	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.1	GO:0071821	FANCM-MHF complex(GO:0071821)
0.0	2.2	GO:0001772	immunological synapse(GO:0001772)
0.0	0.3	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.3	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.5	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	4.1	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.3	GO:0070652	HAUS complex(GO:0070652)
0.0	7.2	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
0.0	3.8	GO:0005581	collagen trimer(GO:0005581)
0.0	1.9	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.3	GO:0070847	core mediator complex(GO:0070847)
0.0	0.3	GO:0097504	Gemini of coiled bodies(GO:0097504)
0.0	0.3	GO:0000974	Prp19 complex(GO:0000974)
0.0	0.9	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.3	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.0	0.3	GO:0061574	ASAP complex(GO:0061574)
0.0	0.2	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0	0.2	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.4	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.4	GO:0035253	ciliary rootlet(GO:0035253)
0.0	1.4	GO:0005798	Golgi-associated vesicle(GO:0005798)
0.0	0.9	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.8	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.0	0.5	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.8	GO:0035861	site of double-strand break(GO:0035861)
0.0	0.4	GO:0033202	DNA helicase complex(GO:0033202)
0.0	0.2	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	2.0	GO:0005882	intermediate filament(GO:0005882)
0.0	0.2	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.2	GO:0016342	catenin complex(GO:0016342)
0.0	0.2	GO:0097346	Swr1 complex(GO:0000812) INO80-type complex(GO:0097346)
0.0	1.3	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.6	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.4	GO:0046540	U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0	0.2	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.1	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.6	GO:0098636	protein complex involved in cell adhesion(GO:0098636)
0.0	0.4	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	1.6	GO:0016605	PML body(GO:0016605)
0.0	1.3	GO:0001726	ruffle(GO:0001726)
0.0	3.4	GO:0031965	nuclear membrane(GO:0031965)
0.0	0.7	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	3.1	GO:0019897	extrinsic component of plasma membrane(GO:0019897)
0.0	1.1	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	1.0	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.0	GO:0031510	SUMO activating enzyme complex(GO:0031510)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.9	11.4	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
1.6	8.2	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
1.5	6.1	GO:0070905	serine binding(GO:0070905)
1.4	5.4	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
1.2	3.6	GO:1901375	acetylcholine transmembrane transporter activity(GO:0005277) norepinephrine transmembrane transporter activity(GO:0005333) acetate ester transmembrane transporter activity(GO:1901375)
1.1	3.2	GO:0004326	tetrahydrofolylpolyglutamate synthase activity(GO:0004326)
0.9	3.7	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
0.8	2.5	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.8	2.5	GO:0016155	formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.8	3.8	GO:0030984	kininogen binding(GO:0030984)
0.7	5.9	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.7	2.2	GO:0016890	site-specific endodeoxyribonuclease activity, specific for altered base(GO:0016890)
0.7	2.0	GO:0003858	3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.7	4.0	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.6	5.1	GO:0005534	galactose binding(GO:0005534)
0.6	2.3	GO:0086038	calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.5	2.7	GO:0008761	UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.5	6.1	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.4	1.6	GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.4	4.5	GO:0102337	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.4	5.5	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.3	12.6	GO:0008392	arachidonic acid epoxygenase activity(GO:0008392)
0.3	1.3	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.3	1.8	GO:0060698	endoribonuclease inhibitor activity(GO:0060698)
0.3	4.0	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.3	1.1	GO:0070506	high-density lipoprotein particle receptor activity(GO:0070506)
0.3	2.8	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.2	0.7	GO:0098973	structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.2	0.7	GO:0016426	tRNA (adenine) methyltransferase activity(GO:0016426)
0.2	0.7	GO:0001156	TFIIIC-class transcription factor binding(GO:0001156)
0.2	0.9	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
0.2	0.6	GO:0050785	disaccharide binding(GO:0048030) advanced glycation end-product receptor activity(GO:0050785)
0.2	2.3	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2	1.0	GO:0070287	ferritin receptor activity(GO:0070287)
0.2	0.8	GO:0005136	interleukin-4 receptor binding(GO:0005136)
0.2	0.6	GO:0033680	ATP-dependent DNA/RNA helicase activity(GO:0033680) triplex DNA binding(GO:0045142)
0.2	0.8	GO:0033797	selenate reductase activity(GO:0033797)
0.2	1.6	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2	1.7	GO:1990948	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.2	1.3	GO:0047179	platelet-activating factor acetyltransferase activity(GO:0047179)
0.2	0.5	GO:0001727	lipid kinase activity(GO:0001727)
0.2	0.7	GO:0030171	voltage-gated proton channel activity(GO:0030171)
0.2	0.5	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.2	0.5	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.2	6.6	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.2	1.4	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.2	1.4	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.2	2.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.2	0.5	GO:0042015	interleukin-20 binding(GO:0042015)
0.1	0.6	GO:0019779	Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1	0.6	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1	0.3	GO:1990932	5.8S rRNA binding(GO:1990932)
0.1	0.9	GO:0019770	IgG receptor activity(GO:0019770)
0.1	6.6	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.1	0.8	GO:0005290	L-histidine transmembrane transporter activity(GO:0005290)
0.1	0.5	GO:0031699	beta-adrenergic receptor activity(GO:0004939) beta-3 adrenergic receptor binding(GO:0031699)
0.1	1.0	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1	0.4	GO:0070698	type I activin receptor binding(GO:0070698)
0.1	1.1	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.1	0.9	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.1	0.4	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
0.1	0.1	GO:0005137	interleukin-5 receptor binding(GO:0005137)
0.1	1.3	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.1	0.6	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1	0.6	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.1	0.4	GO:0046870	cadmium ion binding(GO:0046870)
0.1	0.4	GO:0047389	glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1	0.9	GO:0004568	chitinase activity(GO:0004568)
0.1	1.6	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1	0.8	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.1	0.9	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1	3.7	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.1	0.3	GO:0008988	rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
0.1	1.4	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.1	1.3	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.1	0.2	GO:0043139	5'-3' DNA helicase activity(GO:0043139)
0.1	3.1	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.1	0.3	GO:0017116	single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.1	1.8	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.9	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	1.9	GO:0003746	translation elongation factor activity(GO:0003746)
0.1	0.5	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.1	0.8	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.1	0.2	GO:0004510	tryptophan 5-monooxygenase activity(GO:0004510)
0.1	0.3	GO:0051431	corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1	0.6	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453)
0.1	0.2	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
0.1	1.9	GO:0003951	NAD+ kinase activity(GO:0003951)
0.1	0.4	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
0.1	0.3	GO:0004452	isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.1	0.7	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.1	2.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	2.8	GO:0005109	frizzled binding(GO:0005109)
0.1	0.6	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.5	GO:0008097	5S rRNA binding(GO:0008097)
0.0	1.8	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.0	0.1	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
0.0	1.4	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	1.5	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	4.0	GO:0038024	cargo receptor activity(GO:0038024)
0.0	1.2	GO:0035325	Toll-like receptor binding(GO:0035325)
0.0	0.8	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.2	GO:0098770	FBXO family protein binding(GO:0098770)
0.0	0.1	GO:0019981	interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0	1.6	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0	0.4	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.0	0.9	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.4	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.7	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	1.1	GO:0004190	aspartic-type endopeptidase activity(GO:0004190)
0.0	0.3	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	0.5	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.1	GO:0052795	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0	1.4	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.3	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.2	GO:0000403	Y-form DNA binding(GO:0000403)
0.0	0.6	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.4	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.2	GO:0030942	signal recognition particle binding(GO:0005047) endoplasmic reticulum signal peptide binding(GO:0030942)
0.0	0.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	1.5	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.0	0.3	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	1.5	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	1.1	GO:0019843	rRNA binding(GO:0019843)
0.0	0.2	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	4.2	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.7	GO:0043274	phospholipase binding(GO:0043274)
0.0	4.1	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.2	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	5.3	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	0.4	GO:0019215	intermediate filament binding(GO:0019215)
0.0	1.4	GO:0016790	thiolester hydrolase activity(GO:0016790)
0.0	1.8	GO:0051287	NAD binding(GO:0051287)
0.0	0.5	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.4	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.4	GO:0001968	fibronectin binding(GO:0001968)
0.0	3.4	GO:0005178	integrin binding(GO:0005178)
0.0	0.9	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.3	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.8	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.2	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.2	GO:0005186	pheromone activity(GO:0005186)
0.0	0.2	GO:0003678	DNA helicase activity(GO:0003678)
0.0	0.1	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0	0.1	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.0	0.0	GO:0019807	aspartoacylase activity(GO:0019807)
0.0	0.8	GO:0097472	cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.3	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.2	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.2	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.2	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.7	GO:0043022	ribosome binding(GO:0043022)
0.0	2.0	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	0.7	GO:0030145	manganese ion binding(GO:0030145)
0.0	1.7	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	1.3	GO:0097110	scaffold protein binding(GO:0097110)
0.0	1.1	GO:0016278	lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0	2.3	GO:0042626	ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0	0.7	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.7	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.1	GO:0004852	uroporphyrinogen-III synthase activity(GO:0004852)
0.0	0.4	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.4	GO:0015295	solute:proton symporter activity(GO:0015295)
0.0	0.4	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.1	GO:0034211	GTP-dependent protein kinase activity(GO:0034211)
0.0	0.0	GO:0019948	SUMO activating enzyme activity(GO:0019948)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.4	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.1	4.7	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1	3.7	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1	2.8	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	0.6	PID AURORA A PATHWAY	Aurora A signaling
0.1	3.5	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	19.0	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	13.6	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	2.6	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	3.1	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.8	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.8	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.7	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	1.3	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	2.0	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	2.9	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	2.2	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	1.2	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.3	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	2.5	PID P73PATHWAY	p73 transcription factor network
0.0	0.6	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.7	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	2.5	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.3	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.6	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.4	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.6	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.8	PID ARF6 PATHWAY	Arf6 signaling events
0.0	2.2	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	0.4	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	1.2	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.5	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.5	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.0	0.3	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.4	PID ATR PATHWAY	ATR signaling pathway
0.0	0.6	PID TELOMERASE PATHWAY	Regulation of Telomerase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	16.9	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.5	5.5	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.4	4.7	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.3	4.1	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2	3.6	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.2	15.4	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.2	4.5	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.2	3.1	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.2	2.2	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.1	2.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	0.4	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1	0.4	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	3.7	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	1.1	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.1	5.2	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	5.4	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	1.9	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1	2.7	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1	1.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	9.8	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.1	0.6	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.1	0.5	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1	1.4	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	0.6	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.1	1.3	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1	1.7	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	0.8	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1	5.3	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1	0.5	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	2.8	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	2.4	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.5	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.6	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.8	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.4	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.2	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.8	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	0.6	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.4	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.9	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	2.0	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.0	2.3	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.7	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.6	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.3	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.3	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	1.8	REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE	Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0	0.7	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	0.6	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.7	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.3	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.6	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	1.4	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.3	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.9	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.0	0.4	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.2	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.4	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.5	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	1.9	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.3	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.6	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.3	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.2	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones

Results for Pitx3

Z-value: 0.76

Motif logo

Transcription factors associated with Pitx3

Activity-expression correlation:

Activity profile of Pitx3 motif

Sorted Z-values of Pitx3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Pitx3

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: