ISMARA results: Pou1f1

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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Pou1f1

Z-value: 2.45

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Transcription factors associated with Pou1f1

Gene Symbol	Gene ID	Gene Info
Pou1f1 Ensembl NCBI MGI UniProt	ENSMUSG00000004842.19	Pou1f1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Pou1f1	mm39_v1_chr16_+_65317389_65317434	-0.18	1.3e-01	Click!

Activity profile of Pou1f1 motif

Sorted Z-values of Pou1f1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou1f1

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Promoter	Score	Transcript	Gene	Gene Info
chr5_-_87074380 Show fit	34.28	ENSMUST00000031183.3	Ugt2b1 Ensembl NCBI MGI UniProt Show fit	UDP glucuronosyltransferase 2 family, polypeptide B1
chr5_-_87485023 Show fit	27.96	ENSMUST00000031195.3	Ugt2a3 Ensembl NCBI MGI UniProt Show fit	UDP glucuronosyltransferase 2 family, polypeptide A3
chr5_-_87288177 Show fit	26.38	ENSMUST00000067790.7	Ugt2b5 Ensembl NCBI MGI UniProt Show fit	UDP glucuronosyltransferase 2 family, polypeptide B5
chr13_+_4486105 Show fit	24.66	ENSMUST00000156277.2	Akr1c6 Ensembl NCBI MGI UniProt Show fit	aldo-keto reductase family 1, member C6
chr5_-_87240405 Show fit	22.65	ENSMUST00000132667.2 ENSMUST00000145617.8 ENSMUST00000094649.11	Ugt2b36 Ensembl NCBI MGI UniProt Show fit	UDP glucuronosyltransferase 2 family, polypeptide B36
chr19_-_39637489 Show fit	22.04	ENSMUST00000067328.7	Cyp2c67 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 2, subfamily c, polypeptide 67
chr19_+_39980868 Show fit	18.97	ENSMUST00000049178.3	Cyp2c37 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 2. subfamily c, polypeptide 37
chr10_-_127843377 Show fit	16.39	ENSMUST00000219447.2 ENSMUST00000219780.2 ENSMUST00000219707.2 ENSMUST00000219953.2 ENSMUST00000219183.2	Hsd17b6 Ensembl NCBI MGI UniProt Show fit	hydroxysteroid (17-beta) dehydrogenase 6
chr5_-_145816774 Show fit	16.17	ENSMUST00000035918.8	Cyp3a11 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 3, subfamily a, polypeptide 11
chr4_-_96552349 Show fit	15.91	ENSMUST00000030299.8	Cyp2j5 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 2, subfamily j, polypeptide 5

Showing 1 to 10 of 200 entries

Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	250.3	GO:0007608	sensory perception of smell(GO:0007608)
3.9	129.1	GO:0019373	epoxygenase P450 pathway(GO:0019373)
3.4	47.0	GO:0052695	cellular glucuronidation(GO:0052695)
11.4	34.3	GO:0018879	biphenyl metabolic process(GO:0018879)
10.8	32.5	GO:0009753	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.6	31.2	GO:0030195	negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1	28.5	GO:0008202	steroid metabolic process(GO:0008202)
8.6	25.7	GO:0009073	tyrosine biosynthetic process(GO:0006571) aromatic amino acid family biosynthetic process(GO:0009073) aromatic amino acid family biosynthetic process, prephenate pathway(GO:0009095)
1.9	25.0	GO:0072378	blood coagulation, fibrin clot formation(GO:0072378)
7.8	23.3	GO:0042450	arginine biosynthetic process via ornithine(GO:0042450)

Showing 1 to 10 of 297 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	170.2	GO:0005783	endoplasmic reticulum(GO:0005783)
0.0	146.4	GO:0016021	integral component of membrane(GO:0016021)
0.3	66.3	GO:0072562	blood microparticle(GO:0072562)
0.1	54.5	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.0	52.4	GO:0070062	extracellular exosome(GO:0070062)
0.3	36.0	GO:0000800	lateral element(GO:0000800)
0.8	32.3	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.2	17.5	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
1.6	14.6	GO:0005579	membrane attack complex(GO:0005579)
1.2	13.3	GO:0045179	apical cortex(GO:0045179)

Showing 1 to 10 of 88 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	265.0	GO:0004984	olfactory receptor activity(GO:0004984)
3.8	156.7	GO:0015020	glucuronosyltransferase activity(GO:0015020)
3.9	130.0	GO:0008392	arachidonic acid epoxygenase activity(GO:0008392)
2.0	40.8	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
10.8	32.5	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.6	29.5	GO:0004364	glutathione transferase activity(GO:0004364)
0.2	26.3	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
4.3	25.7	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.2	20.4	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
4.9	19.6	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)

Showing 1 to 10 of 235 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.6	21.8	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.3	20.8	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	10.2	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	3.7	PID E2F PATHWAY	E2F transcription factor network
0.0	2.2	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	2.2	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	2.0	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1	1.8	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1	1.7	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	1.7	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha

Showing 1 to 10 of 31 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	82.0	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
1.2	28.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.5	23.8	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.7	22.5	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.7	14.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
1.2	13.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
3.1	12.3	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.8	11.6	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.7	9.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
2.8	8.5	REACTOME XENOBIOTICS	Genes involved in Xenobiotics

Showing 1 to 10 of 60 entries

Results for Pou1f1

Z-value: 2.45

Motif logo

Transcription factors associated with Pou1f1

Activity-expression correlation:

Activity profile of Pou1f1 motif

Sorted Z-values of Pou1f1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou1f1

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: