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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Pou2f2_Pou3f1

Z-value: 3.46

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Transcription factors associated with Pou2f2_Pou3f1

Gene Symbol Gene ID Gene Info
ENSMUSG00000008496.20 Pou2f2
ENSMUSG00000090125.4 Pou3f1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pou3f1mm39_v1_chr4_+_124550600_124550600-0.594.6e-08Click!
Pou2f2mm39_v1_chr7_-_24831892_248319370.235.4e-02Click!

Activity profile of Pou2f2_Pou3f1 motif

Sorted Z-values of Pou2f2_Pou3f1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou2f2_Pou3f1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_-_68713748 57.49 ENSMUST00000183936.2
ENSMUST00000196863.2
immunoglobulin kappa chain variable 19-93
chr6_+_67586695 57.33 ENSMUST00000103303.3
immunoglobulin kappa variable 1-135
chr6_-_69877961 54.74 ENSMUST00000197290.2
immunoglobulin kappa variable 5-39
chr6_+_68247469 53.74 ENSMUST00000103321.3
immunoglobulin kappa variable 1-110
chr6_-_68609426 53.41 ENSMUST00000103328.3
immunoglobulin kappa variable 10-96
chr6_+_68098030 51.94 ENSMUST00000103317.3
immunoglobulin kappa variable 1-117
chr6_-_69704122 51.75 ENSMUST00000103364.3
immunoglobulin kappa variable 5-48
chr6_+_68026941 50.79 ENSMUST00000103316.2
immunoglobulin kappa chain variable 9-120
chr6_-_69800923 48.72 ENSMUST00000103368.3
immunoglobulin kappa chain variable 5-43
chr12_-_114752425 45.19 ENSMUST00000103510.2
immunoglobulin heavy variable 1-26
chr6_+_70495224 44.14 ENSMUST00000103396.2
immunoglobulin kappa variable 3-12
chr12_-_113802603 43.74 ENSMUST00000103458.3
ENSMUST00000193652.2
immunoglobulin heavy variable 5-16
chr6_-_69741999 43.08 ENSMUST00000103365.3
immunoglobulin kappa variable 12-46
chr6_+_67532481 42.70 ENSMUST00000103302.3
immunoglobulin kappa chain variable 2-137
chr6_-_69877642 42.50 ENSMUST00000103370.3
immunoglobulin kappa variable 5-39
chr12_-_115876396 41.94 ENSMUST00000103547.2
immunoglobulin heavy variable 1-80
chr6_-_68907718 41.41 ENSMUST00000114212.4
immunoglobulin kappa chain variable 13-85
chr6_-_67919524 40.62 ENSMUST00000196768.2
immunoglobulin kappa chain variable 9-124
chr12_-_114710326 40.58 ENSMUST00000103507.2
immunoglobulin heavy variable 1-22
chr12_-_113912416 40.47 ENSMUST00000103464.3
immunoglobulin heavy variable 4-1
chr12_-_114355789 39.23 ENSMUST00000103486.2
immunoglobulin heavy variable 6-3
chr12_-_113790741 39.19 ENSMUST00000103457.3
ENSMUST00000192877.2
immunoglobulin heavy variable 5-15
chr6_+_68402550 38.58 ENSMUST00000103323.3
immunoglobulin kappa variable 16-104
chr12_-_113823290 37.04 ENSMUST00000103459.5
immunoglobulin heavy variable 5-17
chr6_+_68916540 36.85 ENSMUST00000103339.2
immunoglobulin kappa chain variable 13-84
chr12_-_114502585 35.74 ENSMUST00000103496.4
immunoglobulin heavy variable V1-7
chr12_-_114487525 33.81 ENSMUST00000103495.3
immunoglobulin heavy variable V10-3
chr6_-_69835868 33.34 ENSMUST00000103369.2
immunoglobulin kappa chain variable 12-41
chr6_+_70675416 33.07 ENSMUST00000103403.3
immunoglobulin kappa variable 3-2
chr6_+_68279392 32.53 ENSMUST00000103322.3
immunoglobulin kappa variable 2-109
chr12_-_113561594 32.04 ENSMUST00000103444.3
immunoglobulin heavy variable 5-4
chr12_-_113860566 28.43 ENSMUST00000103474.5
immunoglobulin heavy variable 7-1
chr12_-_113958518 28.15 ENSMUST00000103467.2
immunoglobulin heavy variable 14-2
chr12_-_113589576 27.83 ENSMUST00000103446.2
immunoglobulin heavy variable 5-6
chr12_-_114443071 27.81 ENSMUST00000103492.2
immunoglobulin heavy variable 10-1
chr6_+_67838100 27.35 ENSMUST00000200586.2
ENSMUST00000103309.3
immunoglobulin kappa variable 17-127
chr6_-_69792108 27.24 ENSMUST00000103367.3
immunoglobulin kappa variable 12-44
chr3_-_144555062 26.19 ENSMUST00000159989.2
chloride channel accessory 3B
chr6_+_145091196 26.08 ENSMUST00000156849.8
ENSMUST00000132948.2
lymphoid-restricted membrane protein
chr12_-_114252202 25.93 ENSMUST00000195124.6
ENSMUST00000103481.3
immunoglobulin heavy variable 3-6
chr6_+_67873135 25.47 ENSMUST00000103310.3
immunoglobulin kappa variable 14-126
chr12_-_115766700 25.43 ENSMUST00000196587.5
ENSMUST00000103543.3
immunoglobulin heavy variable V1-74
chr12_-_115323192 24.92 ENSMUST00000103531.4
immunoglobulin heavy variable 1-61
chr11_-_106205320 24.75 ENSMUST00000167143.2
CD79B antigen
chr12_-_115276219 23.50 ENSMUST00000103529.4
immunoglobulin heavy variable 1-58
chr6_+_68414401 23.31 ENSMUST00000103324.3
immunoglobulin kappa chain variable 15-103
chr16_-_19079594 23.29 ENSMUST00000103752.3
ENSMUST00000197518.2
immunoglobulin lambda variable 2
chr6_+_70584375 22.81 ENSMUST00000197560.2
immunoglobulin kappa variable 3-7
chr12_-_115916604 22.74 ENSMUST00000196991.2
immunoglobulin heavy variable 1-82
chr12_-_114878652 21.78 ENSMUST00000103515.2
immunoglobulin heavy variable 1-39
chr12_-_114023935 21.73 ENSMUST00000103469.4
immunoglobulin heavy variable V14-3
chr12_-_114012399 20.97 ENSMUST00000103468.3
immunoglobulin heavy variable V11-2
chr12_-_113625906 20.80 ENSMUST00000103448.3
immunoglobulin heavy variable 5-9
chr12_-_114321838 20.06 ENSMUST00000125484.3
immunoglobulin heavy variable 13-2
chrX_-_111608339 19.87 ENSMUST00000039887.4
premature ovarian failure 1B
chr12_-_114398864 19.78 ENSMUST00000103489.2
immunoglobulin heavy variable 6-6
chr15_-_66703471 18.54 ENSMUST00000164163.8
src-like adaptor
chr12_-_114286421 18.53 ENSMUST00000103483.3
immunoglobulin heavy variable V3-8
chr12_-_115172211 18.11 ENSMUST00000103526.3
immunoglobulin heavy variable 1-55
chr3_+_51568588 18.10 ENSMUST00000099106.10
microsomal glutathione S-transferase 2
chr6_-_41535322 17.98 ENSMUST00000193003.2
T cell receptor beta, variable 31
chr1_-_165762469 17.80 ENSMUST00000069609.12
ENSMUST00000111427.9
ENSMUST00000111426.11
POU domain, class 2, transcription factor 1
chr6_+_68196928 17.51 ENSMUST00000103318.6
ENSMUST00000103319.3
immunoglobulin kappa variable 2-112
chr6_-_3494587 17.34 ENSMUST00000049985.15
HEPACAM family member 2
chr6_-_69753317 17.33 ENSMUST00000103366.3
immunoglobulin kappa chain variable 5-45
chr12_-_114226570 17.22 ENSMUST00000103479.4
ENSMUST00000195619.2
immunoglobulin heavy variable 3-5
chr6_-_67014348 17.21 ENSMUST00000204369.2
growth arrest and DNA-damage-inducible 45 alpha
chr6_+_70648743 17.12 ENSMUST00000103401.3
immunoglobulin kappa variable 3-4
chr12_-_115706126 16.74 ENSMUST00000166645.2
ENSMUST00000196690.2
immunoglobulin heavy variable 1-71
chr4_+_3678108 16.63 ENSMUST00000041377.13
ENSMUST00000103010.4
LYN proto-oncogene, Src family tyrosine kinase
chr12_-_113666198 16.59 ENSMUST00000103450.4
immunoglobulin heavy variable 5-12
chr12_-_114621406 16.51 ENSMUST00000192077.2
immunoglobulin heavy variable 1-15
chr6_+_68495964 16.40 ENSMUST00000199510.5
ENSMUST00000103325.3
immunoglobulin kappa chain variable 14-100
chr12_-_114117264 16.23 ENSMUST00000103461.5
immunoglobulin heavy variable 7-3
chr12_-_114843941 16.01 ENSMUST00000191862.6
ENSMUST00000103513.3
immunoglobulin heavy variable 1-36
chr12_-_115798038 15.91 ENSMUST00000103544.3
immunoglobulin heavy variable 1-75
chr10_-_88520877 15.78 ENSMUST00000138734.2
Spi-C transcription factor (Spi-1/PU.1 related)
chr17_+_29709723 15.72 ENSMUST00000024811.9
proviral integration site 1
chr12_-_115471634 15.54 ENSMUST00000103535.3
immunoglobulin heavy variable 1-64
chr12_-_114672701 15.22 ENSMUST00000103505.3
ENSMUST00000193855.2
immunoglobulin heavy variable V1-19
chr5_-_147244074 15.19 ENSMUST00000031650.4
caudal type homeobox 2
chr5_+_137628377 15.18 ENSMUST00000175968.8
leucine-rich repeats and calponin homology (CH) domain containing 4
chr6_-_67014383 15.15 ENSMUST00000043098.9
growth arrest and DNA-damage-inducible 45 alpha
chr11_-_5787743 15.11 ENSMUST00000109837.8
polymerase (DNA directed), mu
chr6_+_67701864 14.59 ENSMUST00000103304.3
immunoglobulin kappa variable 1-133
chr12_-_113928438 14.58 ENSMUST00000103478.4
immunoglobulin heavy variable 3-1
chr12_-_113700190 14.44 ENSMUST00000103452.3
ENSMUST00000192264.2
immunoglobulin heavy variable 5-9-1
chr12_-_115964081 14.26 ENSMUST00000103552.2
immunoglobulin heavy variable 1-85
chr6_+_70640233 14.23 ENSMUST00000103400.3
immunoglobulin kappa chain variable 3-5
chr12_-_115811951 14.17 ENSMUST00000197537.2
immunoglobulin heavy variable 1-76
chr7_-_44180700 14.13 ENSMUST00000205506.2
Spi-B transcription factor (Spi-1/PU.1 related)
chr6_+_68547717 14.11 ENSMUST00000196839.5
ENSMUST00000103327.3
immunoglobulin kappa variable 12-98
chr12_-_115832846 14.06 ENSMUST00000199373.2
immunoglobulin heavy variable 1-78
chr12_-_115109539 14.05 ENSMUST00000192554.6
ENSMUST00000103522.3
immunoglobulin heavy variable 1-52
chr12_-_115884332 14.03 ENSMUST00000103548.3
immunoglobulin heavy variable 1-81
chr11_+_95227836 13.94 ENSMUST00000037502.7
family with sequence similarity 117, member A
chr6_-_67014191 13.86 ENSMUST00000204282.2
growth arrest and DNA-damage-inducible 45 alpha
chr9_-_51240201 13.65 ENSMUST00000039959.11
ENSMUST00000238450.3
RIKEN cDNA 1810046K07 gene
chr6_-_67931692 13.42 ENSMUST00000103313.3
immunoglobulin kappa variable 9-123
chr6_-_148847854 13.26 ENSMUST00000139355.8
ENSMUST00000146457.2
ENSMUST00000054080.15
SIN3-HDAC complex associated factor
chr14_+_79753055 12.89 ENSMUST00000110835.3
ENSMUST00000227192.2
E74-like factor 1
chr12_-_113896002 12.78 ENSMUST00000103463.3
immunoglobulin heavy variable 14-1
chr6_+_70680515 12.52 ENSMUST00000103404.2
immunoglobulin kappa variable 3-1
chr14_-_67953035 12.50 ENSMUST00000163100.8
ENSMUST00000132705.8
ENSMUST00000124045.3
cell division cycle associated 2
chr6_-_41535292 12.47 ENSMUST00000103300.3
T cell receptor beta, variable 31
chrX_-_165992145 12.41 ENSMUST00000112176.8
thymosin, beta 4, X chromosome
chr6_-_68840015 12.40 ENSMUST00000103336.2
immunoglobulin kappa chain variable 1-88
chr1_-_135186176 12.19 ENSMUST00000185752.2
ENSMUST00000003135.14
E74-like factor 3
chr10_+_75784126 12.16 ENSMUST00000000926.3
pre-B lymphocyte gene 3
chr2_+_118877594 12.07 ENSMUST00000152380.8
ENSMUST00000099542.9
kinetochore scaffold 1
chr12_-_115944754 11.67 ENSMUST00000103551.2
immunoglobulin heavy variable 1-84
chr15_-_58261093 11.66 ENSMUST00000227274.3
annexin A13
chr10_+_42736644 11.59 ENSMUST00000105495.8
Scm polycomb group protein like 4
chr12_-_114451189 11.58 ENSMUST00000103493.3
immunoglobulin heavy variable 1-4
chr5_+_137627431 11.41 ENSMUST00000176667.8
leucine-rich repeats and calponin homology (CH) domain containing 4
chr12_-_115611981 11.39 ENSMUST00000103540.3
ENSMUST00000199266.2
immunoglobulin heavy variable V8-12
chr15_+_75734159 11.15 ENSMUST00000023238.6
ENSMUST00000230514.2
ENSMUST00000229331.2
gasdermin D
chr11_+_115714853 11.14 ENSMUST00000103032.11
ENSMUST00000133250.8
ENSMUST00000177736.8
LLGL2 scribble cell polarity complex component
chr12_-_114477427 10.99 ENSMUST00000191803.2
immunoglobulin heavy variable V1-5
chr3_-_144525255 10.85 ENSMUST00000029929.12
chloride channel accessory 3A2
chr6_+_67993691 10.68 ENSMUST00000103314.3
immunoglobulin kappa chain variable 1-122
chr13_-_95661726 10.50 ENSMUST00000022185.10
coagulation factor II (thrombin) receptor-like 1
chr12_-_114815280 10.38 ENSMUST00000103512.3
immunoglobulin heavy variable 1-34
chr17_-_15596230 10.35 ENSMUST00000014917.8
delta like canonical Notch ligand 1
chr11_+_66847446 10.35 ENSMUST00000211300.2
ENSMUST00000150220.2
transmembrane protein 238 like
chr19_-_40260060 10.13 ENSMUST00000068439.13
PDZ and LIM domain 1 (elfin)
chr12_-_36092475 10.07 ENSMUST00000020896.17
tetraspanin 13
chr6_-_148847633 10.04 ENSMUST00000132696.8
SIN3-HDAC complex associated factor
chr6_-_69920632 9.93 ENSMUST00000198880.5
ENSMUST00000103371.3
immunoglobulin kappa chain variable 12-38
chr12_-_115083839 9.72 ENSMUST00000103521.3
immunoglobulin heavy variable 1-50
chr17_+_27276262 9.51 ENSMUST00000049308.9
inositol 1,4,5-triphosphate receptor 3
chr6_+_41098273 9.50 ENSMUST00000103270.4
T cell receptor beta, variable 13-2
chr2_+_118877610 9.30 ENSMUST00000153300.8
ENSMUST00000028799.12
kinetochore scaffold 1
chr11_-_34724458 9.27 ENSMUST00000093191.3
spindle apparatus coiled-coil protein 1
chrX_-_165992311 9.26 ENSMUST00000112172.4
thymosin, beta 4, X chromosome
chr3_+_159201048 8.96 ENSMUST00000120272.8
DEP domain containing 1a
chr19_-_40260286 8.89 ENSMUST00000182432.2
PDZ and LIM domain 1 (elfin)
chr12_-_114057841 8.85 ENSMUST00000103471.2
ENSMUST00000195884.2
immunoglobulin heavy variable 9-1
chr9_-_85209340 8.62 ENSMUST00000187711.2
terminal nucleotidyltransferase 5A
chr12_-_115157739 8.49 ENSMUST00000103525.3
immunoglobulin heavy variable V1-54
chr9_-_85209162 8.47 ENSMUST00000034802.15
terminal nucleotidyltransferase 5A
chr6_+_64706101 8.25 ENSMUST00000101351.6
atonal bHLH transcription factor 1
chr3_+_159201077 7.89 ENSMUST00000029825.14
DEP domain containing 1a
chr12_-_114186874 7.82 ENSMUST00000103477.4
ENSMUST00000192499.3
immunoglobulin heavy variable 7-4
chr6_+_67890534 7.75 ENSMUST00000197406.5
ENSMUST00000103311.3
immunoglobulin kappa variable 11-125
chr17_+_27775637 7.74 ENSMUST00000117254.9
ENSMUST00000231243.2
ENSMUST00000231358.2
ENSMUST00000118570.2
ENSMUST00000231796.2
high mobility group AT-hook 1
chr8_+_121215155 7.73 ENSMUST00000034279.16
genetic suppressor element 1, coiled-coil protein
chr3_+_159201092 7.59 ENSMUST00000106041.3
DEP domain containing 1a
chr1_+_36510670 7.52 ENSMUST00000153128.2
cyclin M4
chr8_+_71069476 7.50 ENSMUST00000052437.6
leucine rich repeat containing 25
chr17_+_27775613 7.44 ENSMUST00000231780.2
ENSMUST00000232253.2
ENSMUST00000232552.2
ENSMUST00000117600.9
high mobility group AT-hook 1
chr4_-_3938352 7.41 ENSMUST00000003369.10
pleiomorphic adenoma gene 1
chr2_+_90927053 7.40 ENSMUST00000132741.3
spleen focus forming virus (SFFV) proviral integration oncogene
chr19_-_46033353 7.25 ENSMUST00000026252.14
ENSMUST00000156585.9
ENSMUST00000185355.7
ENSMUST00000152946.8
LIM domain binding 1
chr8_+_91635192 7.14 ENSMUST00000211403.2
chromodomain helicase DNA binding protein 9
chr16_-_92494203 7.14 ENSMUST00000113956.10
runt related transcription factor 1
chr6_+_67816777 6.77 ENSMUST00000200578.5
ENSMUST00000103308.3
immunoglobulin kappa variable 9-129
chr1_+_52047368 6.65 ENSMUST00000027277.7
signal transducer and activator of transcription 4
chr10_-_79911245 6.48 ENSMUST00000217972.2
strawberry notch 2
chr17_+_27775471 6.45 ENSMUST00000118599.9
ENSMUST00000232265.2
ENSMUST00000232013.2
ENSMUST00000114888.11
ENSMUST00000231874.2
ENSMUST00000119486.9
ENSMUST00000231825.2
ENSMUST00000231866.2
high mobility group AT-hook 1
chr12_-_115557211 6.41 ENSMUST00000103537.3
immunoglobulin heavy variable 1-66
chr16_+_23043474 6.33 ENSMUST00000023601.14
beta galactoside alpha 2,6 sialyltransferase 1
chr12_-_113542610 6.32 ENSMUST00000195468.6
ENSMUST00000103442.3
immunoglobulin heavy variable 5-2
chr12_-_115459678 6.26 ENSMUST00000103534.2
immunoglobulin heavy variable V1-63
chr5_+_93045837 6.22 ENSMUST00000113051.9
shroom family member 3
chr14_+_26722319 6.08 ENSMUST00000035433.10
homeobox gene expressed in ES cells
chr12_-_114073050 6.05 ENSMUST00000103472.4
immunoglobulin heavy variable V9-2
chr4_-_129590372 5.97 ENSMUST00000137640.3
transmembrane protein 39b
chr7_-_4607040 5.92 ENSMUST00000166650.3
protein tyrosine phosphatase, receptor type, H
chr12_-_101785307 5.91 ENSMUST00000021603.9
fibulin 5
chr12_-_101784727 5.76 ENSMUST00000222587.2
fibulin 5
chr13_-_23755374 5.74 ENSMUST00000102969.6
H2A clustered histone 8
chr6_+_68657317 5.69 ENSMUST00000198735.2
immunoglobulin kappa variable 10-95
chr13_+_102830029 5.67 ENSMUST00000022124.10
ENSMUST00000171267.2
ENSMUST00000167144.2
ENSMUST00000170878.2
CD180 antigen
chr16_+_44913974 5.65 ENSMUST00000099498.10
coiled-coil domain containing 80
chr13_+_21906214 5.59 ENSMUST00000224651.2
H2B clustered histone 14
chrX_+_132751729 5.57 ENSMUST00000033602.9
tenomodulin
chr6_+_67768007 5.56 ENSMUST00000196006.5
ENSMUST00000103307.3
immunoglobulin kappa variable 14-130
chr2_-_103133503 5.54 ENSMUST00000111176.9
ets homologous factor
chr6_-_52237765 5.48 ENSMUST00000147595.7
homeobox A13
chr5_-_124003553 5.43 ENSMUST00000057145.7
hydroxycarboxylic acid receptor 2
chr12_-_115031622 5.36 ENSMUST00000194257.2
immunoglobulin heavy variable V8-5
chr12_-_114955196 5.31 ENSMUST00000194865.2
immunoglobulin heavy variable 1-47
chr2_-_147887810 5.24 ENSMUST00000109964.8
forkhead box A2
chrX_+_55500170 5.24 ENSMUST00000039374.9
ENSMUST00000101553.9
ENSMUST00000186445.7
integrator complex subunit 6 like
chr12_-_34578842 5.20 ENSMUST00000110819.4
histone deacetylase 9
chr9_+_50466127 5.10 ENSMUST00000213916.2
interleukin 18
chr18_+_36414122 5.09 ENSMUST00000051301.6
purine rich element binding protein A
chr5_+_144127102 5.08 ENSMUST00000060747.8
basic helix-loop-helix family, member a15
chr3_+_96177010 4.99 ENSMUST00000051089.4
ENSMUST00000177113.2
predicted gene 42743
H2B clustered histone 18
chr12_-_113945961 4.96 ENSMUST00000103466.2
immunoglobulin heavy variable 11-1
chr16_+_11131676 4.89 ENSMUST00000023140.6
tumor necrosis factor receptor superfamily, member 17
chr6_-_69477770 4.85 ENSMUST00000197448.2
immunoglobulin kappa variable 4-58
chr12_-_11258973 4.83 ENSMUST00000049877.3
mesogenin 1
chr4_+_99184137 4.73 ENSMUST00000094955.3
predicted gene 12689
chr7_+_44667377 4.62 ENSMUST00000044111.10
related RAS viral (r-ras) oncogene
chr7_-_113716996 4.61 ENSMUST00000069449.7
related RAS viral (r-ras) oncogene 2
chr11_+_54486925 4.59 ENSMUST00000218995.2
Rap guanine nucleotide exchange factor (GEF) 6
chr7_+_5018453 4.56 ENSMUST00000086349.5
ENSMUST00000207050.2
zinc finger protein 524
predicted gene 44973
chr4_-_63965161 4.53 ENSMUST00000107377.10
tenascin C

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.7 1156.0 GO:0006910 phagocytosis, recognition(GO:0006910)
5.5 16.6 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
3.5 10.5 GO:0070949 positive regulation of eosinophil degranulation(GO:0043311) regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949) positive regulation of renin secretion into blood stream(GO:1900135) positive regulation of eosinophil activation(GO:1902568)
3.5 10.4 GO:0021698 cerebellar cortex structural organization(GO:0021698)
3.2 41.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
3.1 824.6 GO:0002377 immunoglobulin production(GO:0002377)
2.9 8.8 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
2.8 11.1 GO:0051673 membrane disruption in other organism(GO:0051673)
2.8 11.1 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
2.8 8.3 GO:0042668 auditory receptor cell fate determination(GO:0042668)
2.5 17.8 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
2.4 7.3 GO:0043973 histone H3-K4 acetylation(GO:0043973)
2.1 4.1 GO:0032741 positive regulation of interleukin-18 production(GO:0032741)
2.0 4.1 GO:0021502 neural fold elevation formation(GO:0021502)
2.0 12.1 GO:0060847 endothelial cell fate specification(GO:0060847)
1.9 7.5 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
1.8 30.6 GO:0034501 protein localization to kinetochore(GO:0034501)
1.7 15.7 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
1.6 6.5 GO:0071348 cellular response to interleukin-11(GO:0071348)
1.5 18.4 GO:0014807 regulation of somitogenesis(GO:0014807)
1.5 4.5 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
1.5 7.4 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
1.5 8.9 GO:0050916 sensory perception of sweet taste(GO:0050916)
1.4 4.2 GO:0060435 bronchiole development(GO:0060435) trachea cartilage morphogenesis(GO:0060535) intestinal epithelial cell maturation(GO:0060574)
1.4 24.4 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
1.4 21.7 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
1.3 3.9 GO:0098583 mastication(GO:0071626) learned vocalization behavior(GO:0098583)
1.3 5.1 GO:0042231 negative regulation of neutrophil apoptotic process(GO:0033030) interleukin-13 biosynthetic process(GO:0042231)
1.3 6.3 GO:1990743 protein sialylation(GO:1990743)
1.1 5.5 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
1.1 11.7 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
1.0 3.1 GO:0014908 myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.9 4.5 GO:0003409 optic cup structural organization(GO:0003409)
0.9 4.4 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.8 6.6 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.8 2.5 GO:1904172 positive regulation of bleb assembly(GO:1904172)
0.8 2.4 GO:0021660 rhombomere formation(GO:0021594) rhombomere 3 formation(GO:0021660) rhombomere 5 morphogenesis(GO:0021664) rhombomere 5 formation(GO:0021666)
0.8 3.9 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.8 18.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.7 3.0 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.7 3.6 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.7 5.4 GO:0070162 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
0.7 6.1 GO:0030916 otic vesicle formation(GO:0030916)
0.7 2.0 GO:0021759 globus pallidus development(GO:0021759)
0.6 12.2 GO:0060056 mammary gland involution(GO:0060056)
0.6 3.3 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.5 2.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.5 37.0 GO:1902476 chloride transmembrane transport(GO:1902476)
0.5 5.3 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.5 2.9 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.5 4.2 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.5 4.2 GO:0006265 DNA topological change(GO:0006265)
0.4 2.7 GO:2000053 regulation of mismatch repair(GO:0032423) regulation of chondrocyte development(GO:0061181) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.4 7.5 GO:0015693 magnesium ion transport(GO:0015693)
0.4 5.2 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.4 2.6 GO:2000210 positive regulation of anoikis(GO:2000210)
0.4 5.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.4 4.2 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.4 7.6 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.4 21.6 GO:0006284 base-excision repair(GO:0006284)
0.4 2.4 GO:0071484 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.4 2.0 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.4 2.3 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.4 1.9 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.4 11.4 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.4 4.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.4 2.3 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.4 12.9 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.3 2.4 GO:0007527 adult somatic muscle development(GO:0007527)
0.3 1.0 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.3 3.4 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.3 1.9 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.3 25.4 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.3 4.1 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.3 2.7 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.3 5.1 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.3 0.5 GO:1901228 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.2 4.8 GO:0007379 segment specification(GO:0007379)
0.2 1.0 GO:2000230 pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.2 0.9 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.2 1.4 GO:0048539 bone marrow development(GO:0048539)
0.2 0.9 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.2 1.4 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.2 19.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.2 24.7 GO:0030183 B cell differentiation(GO:0030183)
0.2 2.0 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 0.7 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.2 4.5 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 27.3 GO:0007338 single fertilization(GO:0007338)
0.1 5.3 GO:0030225 macrophage differentiation(GO:0030225)
0.1 4.6 GO:0030033 microvillus assembly(GO:0030033)
0.1 3.8 GO:0002076 osteoblast development(GO:0002076)
0.1 0.8 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 0.5 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.1 1.5 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 17.3 GO:0007098 centrosome cycle(GO:0007098)
0.1 7.1 GO:0060325 face morphogenesis(GO:0060325)
0.1 1.3 GO:0002002 regulation of angiotensin levels in blood(GO:0002002) regulation of angiotensin metabolic process(GO:0060177)
0.1 0.9 GO:0006477 protein sulfation(GO:0006477)
0.1 0.8 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.1 0.2 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
0.1 6.0 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.1 0.2 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.1 3.0 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.1 1.7 GO:0016180 snRNA processing(GO:0016180)
0.1 1.9 GO:0097435 fibril organization(GO:0097435)
0.1 4.4 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.1 1.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 1.7 GO:0001967 suckling behavior(GO:0001967)
0.1 0.5 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.8 GO:0019321 pentose metabolic process(GO:0019321)
0.1 3.6 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.1 4.1 GO:0045576 mast cell activation(GO:0045576)
0.0 0.3 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 1.0 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 13.6 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 1.8 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.8 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.7 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 1.8 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 3.5 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 1.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 1.4 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 2.8 GO:0051028 mRNA transport(GO:0051028)
0.0 4.2 GO:0030833 regulation of actin filament polymerization(GO:0030833)
0.0 1.0 GO:0032611 interleukin-1 beta production(GO:0032611)
0.0 1.3 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 1.0 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.8 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
9.4 1156.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
4.2 16.6 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
3.5 24.7 GO:0019814 immunoglobulin complex(GO:0019814)
2.7 21.6 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
2.3 11.7 GO:0071953 elastic fiber(GO:0071953)
1.9 7.6 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
1.6 11.1 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
1.2 9.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.9 3.5 GO:0008623 CHRAC(GO:0008623)
0.8 2.4 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.8 30.6 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.8 3.8 GO:0035976 AP1 complex(GO:0035976)
0.7 4.1 GO:0036019 endolysosome(GO:0036019)
0.6 8.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.6 4.2 GO:0031298 replication fork protection complex(GO:0031298)
0.6 2.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.5 10.5 GO:0031143 pseudopodium(GO:0031143)
0.5 4.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.5 6.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.4 14.9 GO:0030057 desmosome(GO:0030057)
0.4 9.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.4 11.7 GO:0005614 interstitial matrix(GO:0005614)
0.3 3.4 GO:0045179 apical cortex(GO:0045179)
0.3 3.0 GO:0001674 female germ cell nucleus(GO:0001674)
0.3 688.8 GO:0005615 extracellular space(GO:0005615)
0.3 41.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.3 2.5 GO:0005826 actomyosin contractile ring(GO:0005826)
0.3 5.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.3 1.5 GO:0031251 PAN complex(GO:0031251)
0.3 3.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 2.6 GO:0070822 Sin3-type complex(GO:0070822)
0.2 26.6 GO:0016605 PML body(GO:0016605)
0.2 0.9 GO:0032444 activin responsive factor complex(GO:0032444) SMAD2-SMAD3 protein complex(GO:0071144)
0.2 3.4 GO:0035102 PRC1 complex(GO:0035102)
0.2 28.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 2.4 GO:0070938 contractile ring(GO:0070938)
0.1 2.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 7.5 GO:0005604 basement membrane(GO:0005604)
0.1 2.7 GO:0000178 exosome (RNase complex)(GO:0000178)
0.1 48.0 GO:0016607 nuclear speck(GO:0016607)
0.1 1.7 GO:0032039 integrator complex(GO:0032039)
0.1 1.4 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.1 0.8 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 2.2 GO:0031519 PcG protein complex(GO:0031519)
0.1 12.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 17.3 GO:0005819 spindle(GO:0005819)
0.1 5.2 GO:0035097 histone methyltransferase complex(GO:0035097)
0.1 3.1 GO:0005801 cis-Golgi network(GO:0005801)
0.1 3.7 GO:0032420 stereocilium(GO:0032420)
0.0 0.5 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 1.5 GO:0045095 keratin filament(GO:0045095)
0.0 3.8 GO:0005902 microvillus(GO:0005902)
0.0 2.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 4.1 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 7.7 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 2.8 GO:0005681 spliceosomal complex(GO:0005681)
0.0 1.5 GO:0036064 ciliary basal body(GO:0036064)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.7 1156.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
4.5 18.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
4.2 16.6 GO:0005128 erythropoietin receptor binding(GO:0005128)
2.6 10.5 GO:0015057 thrombin receptor activity(GO:0015057)
2.4 21.6 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
2.4 9.5 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
2.1 22.8 GO:1901611 phosphatidylglycerol binding(GO:1901611)
1.4 4.2 GO:0097100 supercoiled DNA binding(GO:0097100)
1.3 9.3 GO:0043515 kinetochore binding(GO:0043515)
1.3 5.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
1.3 132.7 GO:0003823 antigen binding(GO:0003823)
1.2 39.9 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
1.2 15.7 GO:0043024 ribosomal small subunit binding(GO:0043024)
1.1 6.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
1.0 3.0 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.8 2.4 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.7 19.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.6 18.3 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.6 3.6 GO:0045322 unmethylated CpG binding(GO:0045322)
0.5 10.4 GO:0030957 Tat protein binding(GO:0030957)
0.5 7.4 GO:0051525 NFAT protein binding(GO:0051525)
0.5 1.9 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.5 7.3 GO:0030274 LIM domain binding(GO:0030274)
0.5 15.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.5 3.7 GO:0070644 vitamin D response element binding(GO:0070644)
0.5 5.9 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.5 4.5 GO:0045545 syndecan binding(GO:0045545)
0.4 4.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.4 8.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.4 2.0 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.4 2.7 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.4 7.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.4 3.4 GO:0032052 long-chain fatty acid transporter activity(GO:0005324) bile acid binding(GO:0032052)
0.4 4.8 GO:0070700 BMP receptor binding(GO:0070700)
0.3 0.9 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.3 7.6 GO:0000400 four-way junction DNA binding(GO:0000400)
0.3 2.7 GO:0004126 cytidine deaminase activity(GO:0004126)
0.3 19.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.3 4.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.3 14.4 GO:0003785 actin monomer binding(GO:0003785)
0.3 2.5 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.3 39.6 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.3 58.9 GO:0047485 protein N-terminus binding(GO:0047485)
0.3 1.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.3 2.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2 5.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 2.4 GO:0034046 poly(G) binding(GO:0034046)
0.2 1.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 4.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 4.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.2 5.4 GO:0001614 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.2 3.8 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 0.8 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.2 5.6 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.9 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 2.7 GO:0070411 I-SMAD binding(GO:0070411)
0.1 2.0 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 0.7 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 1.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 2.8 GO:0005112 Notch binding(GO:0005112)
0.1 15.6 GO:0005178 integrin binding(GO:0005178)
0.1 5.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 7.5 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 1.0 GO:1901567 icosanoid binding(GO:0050542) icosatetraenoic acid binding(GO:0050543) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.1 2.3 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 2.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 3.0 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.1 2.0 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 27.0 GO:0005096 GTPase activator activity(GO:0005096)
0.1 1.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.4 GO:0070628 proteasome binding(GO:0070628)
0.1 0.8 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.2 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.1 4.2 GO:0002039 p53 binding(GO:0002039)
0.1 3.6 GO:0019003 GDP binding(GO:0019003)
0.0 2.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 2.8 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 5.0 GO:0004386 helicase activity(GO:0004386)
0.0 1.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 42.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
1.0 32.3 PID IL5 PATHWAY IL5-mediated signaling events
0.6 15.1 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.6 3.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.4 25.0 PID BCR 5PATHWAY BCR signaling pathway
0.4 33.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.4 11.7 PID IL27 PATHWAY IL27-mediated signaling events
0.4 17.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.4 11.9 ST GAQ PATHWAY G alpha q Pathway
0.3 12.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.3 10.5 ST GA12 PATHWAY G alpha 12 Pathway
0.3 17.9 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.2 4.6 PID RAS PATHWAY Regulation of Ras family activation
0.1 2.7 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 4.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 8.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 2.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 7.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 10.5 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 5.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 8.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 3.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 3.8 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 11.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 ST GA13 PATHWAY G alpha 13 Pathway
0.0 1.9 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 4.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 1.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 21.6 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
1.4 14.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
1.0 16.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.7 10.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.6 17.8 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.5 25.0 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.5 9.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.4 6.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.4 18.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.3 4.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.3 4.4 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.3 4.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 6.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 2.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 2.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 4.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 16.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 3.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 5.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 1.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 10.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 2.0 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 10.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 3.3 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 5.1 REACTOME SIGNALING BY ILS Genes involved in Signaling by Interleukins
0.0 4.9 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 2.3 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades