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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Pou3f2

Z-value: 1.17

Motif logo

Transcription factors associated with Pou3f2

Gene Symbol Gene ID Gene Info
ENSMUSG00000095139.3 Pou3f2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pou3f2mm39_v1_chr4_-_22488296_224883660.473.0e-05Click!

Activity profile of Pou3f2 motif

Sorted Z-values of Pou3f2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou3f2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr8_+_21999274 12.74 ENSMUST00000084042.4
defensin, alpha, 20
chr8_+_21868531 12.59 ENSMUST00000170275.4
defensin, alpha, 2
chr8_+_21881827 12.42 ENSMUST00000120874.5
defensin, alpha, 33
chr8_+_22224506 12.36 ENSMUST00000080533.6
defensin, alpha, 24
chr8_+_22019048 12.21 ENSMUST00000084041.4
defensin, alpha, 32
chr8_+_22108199 10.31 ENSMUST00000074343.6
defensin, alpha, 26
chr4_+_11758147 10.11 ENSMUST00000029871.12
ENSMUST00000108303.2
cadherin 17
chr2_-_62313981 8.48 ENSMUST00000136686.2
ENSMUST00000102733.10
glucagon
chrX_+_95499968 7.98 ENSMUST00000079322.12
ENSMUST00000113838.8
hephaestin
chr8_+_21739729 7.57 ENSMUST00000098895.3
defensin, alpha, 40
chr11_-_78313043 6.69 ENSMUST00000001122.6
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr13_-_110416637 6.13 ENSMUST00000167824.3
ENSMUST00000224180.2
RAB3C, member RAS oncogene family
chr10_+_115979787 6.08 ENSMUST00000105271.9
protein tyrosine phosphatase, receptor type, R
chr1_-_162641495 6.04 ENSMUST00000144916.8
ENSMUST00000140274.2
flavin containing monooxygenase 4
chr16_-_48232770 5.72 ENSMUST00000212197.2
predicted gene 5485
chr2_+_177834868 5.68 ENSMUST00000103065.2
phosphatase and actin regulator 3
chr17_-_34694911 5.68 ENSMUST00000065841.5
butyrophilin-like 4
chr8_+_21805562 5.20 ENSMUST00000167683.3
ENSMUST00000168340.2
defensin, alpha, 27
chr11_-_42070517 4.94 ENSMUST00000206105.2
ENSMUST00000153147.3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr14_-_88708782 4.81 ENSMUST00000192557.2
ENSMUST00000061628.7
protocadherin 20
chr6_+_40605758 4.76 ENSMUST00000202636.4
ENSMUST00000201148.4
ENSMUST00000071535.10
maltase-glucoamylase
chr5_+_14075281 4.63 ENSMUST00000073957.8
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr12_+_52746158 4.53 ENSMUST00000095737.5
A kinase (PRKA) anchor protein 6
chr3_+_55369149 4.34 ENSMUST00000199585.5
ENSMUST00000070418.9
doublecortin-like kinase 1
chr4_-_110143777 4.31 ENSMUST00000138972.8
ELAV like RNA binding protein 4
chr8_+_22073022 4.05 ENSMUST00000098887.4
defensin, alpha, 28
chr13_-_51723473 3.94 ENSMUST00000239056.2
ENSMUST00000223543.3
src homology 2 domain-containing transforming protein C3
chr7_+_51271742 3.52 ENSMUST00000032710.7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr15_+_30457772 3.43 ENSMUST00000228282.2
catenin (cadherin associated protein), delta 2
chr4_-_149211145 3.41 ENSMUST00000030815.3
cortistatin
chr2_+_65760477 3.34 ENSMUST00000176109.8
cysteine-serine-rich nuclear protein 3
chr2_-_79738773 3.31 ENSMUST00000102652.10
ENSMUST00000102651.10
phosphodiesterase 1A, calmodulin-dependent
chr3_-_144514386 3.29 ENSMUST00000197013.2
chloride channel accessory 3A2
chr13_-_110417421 3.19 ENSMUST00000223922.2
RAB3C, member RAS oncogene family
chr15_+_39255185 3.06 ENSMUST00000228839.2
regulating synaptic membrane exocytosis 2
chr2_-_144369261 3.05 ENSMUST00000163701.2
ENSMUST00000081982.12
double zinc ribbon and ankyrin repeat domains 1
chr2_-_79738734 3.03 ENSMUST00000090756.11
phosphodiesterase 1A, calmodulin-dependent
chr8_+_21574411 2.96 ENSMUST00000095425.2
defensin, alpha, 25
chr7_-_140402037 2.95 ENSMUST00000106052.2
ENSMUST00000080651.13
zinc finger protein 941
chr9_-_69945358 2.94 ENSMUST00000034751.6
glucosaminyl (N-acetyl) transferase 3, mucin type
chr2_+_65451100 2.93 ENSMUST00000144254.6
ENSMUST00000028377.14
sodium channel, voltage-gated, type II, alpha
chr14_-_104081119 2.93 ENSMUST00000227824.2
ENSMUST00000172237.2
endothelin receptor type B
chr2_-_136229849 2.93 ENSMUST00000035264.9
ENSMUST00000077200.4
p21 (RAC1) activated kinase 5
chr3_+_28038283 2.90 ENSMUST00000067757.11
ENSMUST00000123539.8
phospholipase D1
chr2_+_20727274 2.85 ENSMUST00000114607.8
enhancer trap locus 4
chr14_-_54655079 2.80 ENSMUST00000226753.2
ENSMUST00000197440.5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr11_-_60243695 2.73 ENSMUST00000095254.12
ENSMUST00000102683.11
ENSMUST00000093048.13
ENSMUST00000093046.13
ENSMUST00000064019.15
ENSMUST00000102682.5
target of myb1-like 2 (chicken)
chr2_+_134627987 2.64 ENSMUST00000131552.5
ENSMUST00000110116.8
phospholipase C, beta 1
chr5_-_99391073 2.56 ENSMUST00000166484.2
RasGEF domain family, member 1B
chr6_-_69394425 2.55 ENSMUST00000199160.2
immunoglobulin kappa chain variable 4-61
chr6_-_69204417 2.41 ENSMUST00000103346.3
immunoglobulin kappa chain variable 4-72
chr14_+_60615128 2.39 ENSMUST00000022561.9
APC membrane recruitment 2
chr6_-_69245427 2.39 ENSMUST00000103348.3
immunoglobulin kappa chain variable 4-70
chr3_-_157630690 2.36 ENSMUST00000118539.2
cystathionase (cystathionine gamma-lyase)
chr14_-_104081827 2.27 ENSMUST00000022718.11
endothelin receptor type B
chr4_-_138123700 2.22 ENSMUST00000105032.4
family with sequence similarity 43, member B
chrX_-_144288071 2.20 ENSMUST00000112835.8
ENSMUST00000143610.3
angiomotin
chr6_-_138399896 2.12 ENSMUST00000161450.8
ENSMUST00000163024.8
ENSMUST00000162185.8
LIM domain only 3
chr5_+_107645626 2.07 ENSMUST00000152474.8
ENSMUST00000060553.8
BTB (POZ) domain containing 8
chr10_+_62860291 2.06 ENSMUST00000020262.5
phenazine biosynthesis-like protein domain containing 2
chrX_-_42256694 2.06 ENSMUST00000115058.8
ENSMUST00000115059.8
teneurin transmembrane protein 1
chr18_+_38429688 2.05 ENSMUST00000170811.8
ENSMUST00000072376.13
ENSMUST00000237903.2
ENSMUST00000236116.2
ENSMUST00000237824.2
ENSMUST00000236982.2
ENSMUST00000235549.2
ENSMUST00000237416.2
ENSMUST00000237089.2
ring finger protein 14
chr11_-_99134885 2.02 ENSMUST00000103132.10
ENSMUST00000038214.7
keratin 222
chrX_-_58211440 1.99 ENSMUST00000119306.2
fibroblast growth factor 13
chr19_-_7183626 1.93 ENSMUST00000025679.11
OTU domain, ubiquitin aldehyde binding 1
chr6_-_69282389 1.88 ENSMUST00000103350.3
immunoglobulin kappa variable 4-68
chr1_-_134731516 1.86 ENSMUST00000238280.2
protein phosphatase 1, regulatory subunit 12B
chr6_-_93890520 1.84 ENSMUST00000203688.3
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr1_+_34160331 1.83 ENSMUST00000183006.5
dystonin
chr6_-_69377328 1.78 ENSMUST00000198345.2
immunoglobulin kappa variable 4-62
chr5_-_66211842 1.74 ENSMUST00000200852.4
RNA binding motif protein 47
chr4_-_108637979 1.74 ENSMUST00000106657.8
zinc finger, FYVE domain containing 9
chr7_+_91321500 1.73 ENSMUST00000238619.2
ENSMUST00000238467.2
discs large MAGUK scaffold protein 2
chr16_+_44687460 1.67 ENSMUST00000102805.4
Cd200 receptor 2
chr9_+_48073296 1.62 ENSMUST00000216998.2
ENSMUST00000215780.2
neurexophilin and PC-esterase domain family, member 4
chr2_-_84481058 1.56 ENSMUST00000111670.9
ENSMUST00000111697.9
ENSMUST00000111696.8
ENSMUST00000111678.8
ENSMUST00000111690.8
ENSMUST00000111695.8
ENSMUST00000111677.8
ENSMUST00000111698.8
ENSMUST00000099941.9
ENSMUST00000111676.8
ENSMUST00000111694.8
ENSMUST00000111675.8
ENSMUST00000111689.8
ENSMUST00000111687.8
ENSMUST00000111692.8
ENSMUST00000111685.8
ENSMUST00000111686.8
ENSMUST00000111688.8
ENSMUST00000111693.8
ENSMUST00000111684.8
catenin (cadherin associated protein), delta 1
chr8_-_39128662 1.54 ENSMUST00000118896.2
sarcoglycan zeta
chr17_-_24382638 1.46 ENSMUST00000129523.3
ENSMUST00000138685.3
ENSMUST00000040735.12
amidohydrolase domain containing 2
chr4_-_108637700 1.44 ENSMUST00000106658.8
zinc finger, FYVE domain containing 9
chr14_+_84680993 1.31 ENSMUST00000071370.7
protocadherin 17
chr6_+_140378688 1.27 ENSMUST00000203774.3
pleckstrin homology domain containing, family A member 5
chr6_-_144978557 1.24 ENSMUST00000136819.3
branched chain aminotransferase 1, cytosolic
chr11_+_95925711 1.20 ENSMUST00000006217.10
ENSMUST00000107700.4
SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)
chr2_-_84481020 1.20 ENSMUST00000067232.10
catenin (cadherin associated protein), delta 1
chr9_+_88462944 1.15 ENSMUST00000164661.4
ENSMUST00000215498.2
ENSMUST00000216686.2
tripartite motif-containing 43A
chr9_-_103569984 1.13 ENSMUST00000049452.15
transmembrane protein 108
chr6_+_41582416 1.08 ENSMUST00000114732.3
Eph receptor B6
chr3_+_141171347 1.04 ENSMUST00000130636.8
unc-5 netrin receptor C
chr9_+_74959259 1.03 ENSMUST00000170310.2
ENSMUST00000166549.2
cAMP-regulated phosphoprotein 19
chr3_+_141171322 1.02 ENSMUST00000075282.10
unc-5 netrin receptor C
chr6_-_119940694 1.02 ENSMUST00000161512.3
WNK lysine deficient protein kinase 1
chr19_+_31060237 1.00 ENSMUST00000066039.8
cleavage stimulation factor, 3' pre-RNA subunit 2, tau
chr8_-_111985824 0.98 ENSMUST00000169020.8
ENSMUST00000003404.9
golgi apparatus protein 1
chr1_-_150268470 0.97 ENSMUST00000006167.13
ENSMUST00000097547.10
odr4 GPCR localization factor homolog
chr19_-_6910195 0.97 ENSMUST00000236443.2
potassium channel, subfamily K, member 4
chr18_-_36828978 0.95 ENSMUST00000115682.2
Riken cDNA E230025N22 gene
chr2_-_84481101 0.95 ENSMUST00000111691.2
catenin (cadherin associated protein), delta 1
chr2_-_84480804 0.94 ENSMUST00000066177.10
catenin (cadherin associated protein), delta 1
chr19_-_11816583 0.86 ENSMUST00000214887.2
olfactory receptor 1417
chr15_-_100301124 0.85 ENSMUST00000124324.2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr11_+_60244132 0.84 ENSMUST00000070805.13
ENSMUST00000094140.9
ENSMUST00000108723.9
ENSMUST00000108722.5
dynein regulatory complex subunit 3
chr6_-_144993362 0.83 ENSMUST00000149769.6
branched chain aminotransferase 1, cytosolic
chr10_-_77845571 0.82 ENSMUST00000020522.9
phosphofructokinase, liver, B-type
chr9_+_54441404 0.81 ENSMUST00000118413.3
SH2 domain containing 7
chr11_+_72580823 0.79 ENSMUST00000155998.2
ankyrin repeat and FYVE domain containing 1
chr7_-_142215595 0.73 ENSMUST00000145896.3
insulin-like growth factor 2
chr18_-_75094323 0.71 ENSMUST00000066532.5
lipase, endothelial
chr10_+_79978127 0.70 ENSMUST00000003156.15
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr11_-_98620200 0.67 ENSMUST00000126565.2
ENSMUST00000100500.9
ENSMUST00000017354.13
mediator complex subunit 24
chr6_+_67768007 0.65 ENSMUST00000196006.5
ENSMUST00000103307.3
immunoglobulin kappa variable 14-130
chr6_-_12749192 0.64 ENSMUST00000172356.8
thrombospondin, type I, domain containing 7A
chr9_-_88974735 0.64 ENSMUST00000189557.2
ENSMUST00000167113.8
tripartite motif-containing 43B
chr10_-_130002635 0.64 ENSMUST00000216530.2
olfactory receptor 825
chr10_+_79978152 0.62 ENSMUST00000105366.2
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr4_+_129030710 0.61 ENSMUST00000102600.4
fibronectin type III domain containing 5
chr9_-_105398346 0.61 ENSMUST00000176770.8
ENSMUST00000085133.13
ATPase, Ca++-sequestering
chr6_-_90201420 0.60 ENSMUST00000076086.3
vomeronasal 1 receptor 53
chr17_+_71511642 0.59 ENSMUST00000126681.8
lipin 2
chrX_-_163787825 0.58 ENSMUST00000114890.3
predicted gene, 17604
chr10_+_57670431 0.56 ENSMUST00000151623.8
ENSMUST00000020022.8
sphingomyelin phosphodiesterase, acid-like 3A
chr18_+_5593566 0.56 ENSMUST00000160910.2
zinc finger E-box binding homeobox 1
chr6_-_12749409 0.55 ENSMUST00000119581.7
thrombospondin, type I, domain containing 7A
chr19_+_55169148 0.55 ENSMUST00000154886.8
ENSMUST00000120936.8
ENSMUST00000025936.12
tectorin beta
chr4_+_138926577 0.53 ENSMUST00000145368.8
capping protein (actin filament) muscle Z-line, beta
chr10_-_107747995 0.52 ENSMUST00000165341.5
otogelin-like
chr7_-_132616977 0.51 ENSMUST00000169570.8
C-terminal binding protein 2
chr7_+_27977141 0.50 ENSMUST00000094651.4
EP300 interacting inhibitor of differentiation 2B
chr10_+_17598961 0.50 ENSMUST00000038107.9
ENSMUST00000219558.2
ENSMUST00000218370.2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr14_+_50722917 0.48 ENSMUST00000071932.5
olfactory receptor 741
chr10_+_56253531 0.45 ENSMUST00000220194.2
ENSMUST00000218834.2
gap junction protein, alpha 1
chr13_+_96524802 0.41 ENSMUST00000099295.6
POC5 centriolar protein
chr2_-_86067177 0.39 ENSMUST00000099900.2
olfactory receptor 1048
chr8_-_41507808 0.39 ENSMUST00000093534.11
mitochondrial tumor suppressor 1
chr19_+_12655487 0.37 ENSMUST00000215134.2
ENSMUST00000049724.8
olfactory receptor 1443
chr2_-_88990751 0.36 ENSMUST00000216833.2
ENSMUST00000216976.2
olfactory receptor 1224, pseudogene 1
chr8_-_25066313 0.36 ENSMUST00000121992.2
indoleamine 2,3-dioxygenase 2
chr2_+_144441817 0.35 ENSMUST00000028917.7
D-tyrosyl-tRNA deacylase 1
chr16_+_36695479 0.34 ENSMUST00000023534.7
ENSMUST00000114812.9
ENSMUST00000134616.8
golgi autoantigen, golgin subfamily b, macrogolgin 1
chr1_+_9978863 0.31 ENSMUST00000052843.12
ENSMUST00000171802.8
ENSMUST00000125294.9
ENSMUST00000140948.9
minichromosome maintenance domain containing 2
chr12_-_31401432 0.26 ENSMUST00000110857.5
dihydrolipoamide dehydrogenase
chr13_-_23041731 0.24 ENSMUST00000228645.2
vomeronasal 1 receptor 211
chr13_+_25240138 0.24 ENSMUST00000069614.7
doublecortin domain containing 2a
chr17_+_85264134 0.23 ENSMUST00000112305.10
protein phosphatase 1B, magnesium dependent, beta isoform
chr3_+_142470806 0.21 ENSMUST00000029938.10
general transcription factor IIB
chrX_+_82898974 0.21 ENSMUST00000239269.2
dystrophin, muscular dystrophy
chr11_+_49169131 0.19 ENSMUST00000213323.2
olfactory receptor 1393
chr15_-_83033471 0.19 ENSMUST00000129372.2
polymerase (DNA-directed), delta interacting protein 3
chr12_+_51424343 0.18 ENSMUST00000219434.2
ENSMUST00000021335.7
Sec1 family domain containing 1
chr6_-_66787481 0.17 ENSMUST00000228862.2
ENSMUST00000227285.2
ENSMUST00000228008.2
ENSMUST00000228651.2
ENSMUST00000227555.2
vomeronasal 1 receptor 39
chr9_+_38278192 0.17 ENSMUST00000216168.2
olfactory receptor 250
chr5_+_122422428 0.17 ENSMUST00000053426.15
PTC7 protein phosphatase homolog
chr14_+_5894220 0.16 ENSMUST00000063750.8
retinoic acid receptor, beta
chr16_-_36605147 0.16 ENSMUST00000165531.9
solute carrier family 15 (H+/peptide transporter), member 2
chr2_+_80145805 0.15 ENSMUST00000028392.8
DnaJ heat shock protein family (Hsp40) member C10
chrX_+_163202778 0.15 ENSMUST00000208741.2
ENSMUST00000033754.15
ENSMUST00000208697.2
ENSMUST00000208261.2
phosphatidylinositol glycan anchor biosynthesis, class A
chr17_+_24026892 0.11 ENSMUST00000191385.3
serine/arginine repetitive matrix 2
chr7_-_86046700 0.10 ENSMUST00000215733.2
olfactory receptor 303
chr7_+_104226521 0.10 ENSMUST00000217466.2
ENSMUST00000215585.3
olfactory receptor 653
chr1_+_90531183 0.10 ENSMUST00000186750.2
COP9 signalosome subunit 8
chr13_-_105430889 0.09 ENSMUST00000226044.2
ring finger protein 180
chr2_-_85917726 0.09 ENSMUST00000216886.2
ENSMUST00000213333.2
ENSMUST00000216020.2
olfactory receptor 1037
chr2_-_87543523 0.09 ENSMUST00000214209.2
olfactory receptor 1137
chr12_+_69288606 0.08 ENSMUST00000063445.13
kelch domain containing 1
chrX_-_95499889 0.07 ENSMUST00000164693.8
ENSMUST00000119035.9
heat shock transcription factor 3
chr16_-_58910185 0.07 ENSMUST00000215647.2
olfactory receptor 191
chr2_+_86338805 0.07 ENSMUST00000076263.2
olfactory receptor 1076
chr6_-_58418303 0.02 ENSMUST00000228577.2
ENSMUST00000227466.2
vomeronasal 1 receptor 30
chr2_-_88947627 0.01 ENSMUST00000217635.2
ENSMUST00000143255.3
ENSMUST00000213404.2
olfactory receptor 1221
chr2_-_89084074 0.01 ENSMUST00000216392.2
olfactory receptor 1228

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
1.1 8.5 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
1.0 6.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
1.0 2.9 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.9 2.6 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) activation of meiosis involved in egg activation(GO:0060466) cellular response to interleukin-12(GO:0071349) response to fluoride(GO:1902617) response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.9 5.2 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.8 4.7 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.8 6.0 GO:0042737 drug catabolic process(GO:0042737)
0.8 4.5 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.7 2.2 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.7 25.1 GO:0019731 antibacterial humoral response(GO:0019731)
0.6 2.4 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343)
0.4 3.5 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.3 1.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.3 2.4 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.3 6.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.3 2.0 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.3 1.1 GO:0001806 type IV hypersensitivity(GO:0001806)
0.3 2.9 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.3 2.1 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.2 1.0 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.2 8.8 GO:0006825 copper ion transport(GO:0006825)
0.2 3.1 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.2 2.9 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.2 4.9 GO:0071420 cellular response to histamine(GO:0071420)
0.2 1.5 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.2 1.0 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.2 2.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.2 0.7 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.2 12.6 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.2 3.2 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.2 0.6 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.2 0.5 GO:0060156 vascular transport(GO:0010232) milk ejection(GO:0060156)
0.1 0.8 GO:0032439 endosome localization(GO:0032439)
0.1 0.5 GO:0035802 adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802)
0.1 3.0 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 1.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.3 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 4.6 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 1.0 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 1.7 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.1 4.3 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 1.3 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.1 0.2 GO:0021627 olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
0.1 0.8 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.1 0.3 GO:0009106 lipoate metabolic process(GO:0009106)
0.1 0.7 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 3.3 GO:0043276 anoikis(GO:0043276)
0.1 7.2 GO:0019882 antigen processing and presentation(GO:0019882)
0.1 4.9 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.9 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 2.1 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 1.0 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.5 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.4 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 3.7 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 13.3 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.6 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 1.3 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.2 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.6 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 9.2 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.2 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 2.5 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.5 GO:0019321 pentose metabolic process(GO:0019321)
0.0 6.7 GO:0098656 anion transmembrane transport(GO:0098656)
0.0 0.4 GO:0046218 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.0 4.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 3.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 7.2 GO:0007612 learning(GO:0007612)
0.0 0.6 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.7 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 1.0 GO:1903318 negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.0 0.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 2.4 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.6 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.5 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.4 1.2 GO:0000814 ESCRT II complex(GO:0000814)
0.3 4.7 GO:0005915 zonula adherens(GO:0005915)
0.3 4.3 GO:0042788 polysomal ribosome(GO:0042788)
0.2 1.8 GO:0031673 H zone(GO:0031673)
0.2 4.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 1.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 0.8 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 1.3 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 0.8 GO:0070826 paraferritin complex(GO:0070826)
0.1 3.5 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 2.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.8 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 3.1 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.3 GO:0043159 acrosomal matrix(GO:0043159)
0.1 3.2 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.7 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 1.0 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 18.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.5 GO:0097470 ribbon synapse(GO:0097470)
0.0 9.0 GO:0008021 synaptic vesicle(GO:0008021)
0.0 3.0 GO:0014704 intercalated disc(GO:0014704)
0.0 1.0 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 1.9 GO:0031672 A band(GO:0031672)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 8.9 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 50.3 GO:0005615 extracellular space(GO:0005615)
0.0 1.6 GO:0005882 intermediate filament(GO:0005882)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 1.8 GO:0005923 bicellular tight junction(GO:0005923)
0.0 2.6 GO:0043209 myelin sheath(GO:0043209)
0.0 0.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 10.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
1.7 5.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.8 4.8 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.7 2.9 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.7 8.0 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.6 4.9 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.6 6.3 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.6 2.2 GO:0043532 angiostatin binding(GO:0043532)
0.5 6.0 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.4 2.9 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.3 9.3 GO:0031489 myosin V binding(GO:0031489)
0.3 1.0 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.3 1.9 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.3 2.1 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.3 2.1 GO:0005042 netrin receptor activity(GO:0005042)
0.3 4.5 GO:0043495 protein anchor(GO:0043495)
0.2 4.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 2.9 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 0.8 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.2 0.6 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.1 2.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 3.5 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.1 5.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.8 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.4 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 2.4 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.7 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 3.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 2.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 3.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 4.0 GO:0017091 AU-rich element binding(GO:0017091)
0.1 2.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 9.5 GO:0005179 hormone activity(GO:0005179)
0.1 1.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.0 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 1.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.5 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 1.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.5 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 1.1 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.3 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 2.1 GO:0050681 androgen receptor binding(GO:0050681)
0.0 2.5 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 5.8 GO:0008013 beta-catenin binding(GO:0008013)
0.0 6.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 6.7 GO:0015293 symporter activity(GO:0015293)
0.0 0.5 GO:0050693 LBD domain binding(GO:0050693)
0.0 1.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 2.7 GO:0030276 clathrin binding(GO:0030276)
0.0 1.8 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 1.0 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.5 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.4 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 3.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 12.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 8.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.6 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 2.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 3.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 3.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.1 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.8 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.4 6.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.4 8.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 4.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 2.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 6.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.2 8.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.2 4.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 3.9 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 4.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 2.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 5.9 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 2.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 2.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.0 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 2.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.8 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 2.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 2.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases