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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Pou3f3

Z-value: 0.44

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Transcription factors associated with Pou3f3

Gene Symbol Gene ID Gene Info
Pou3f3
ENSMUSG00000045515.5 Pou3f3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pou3f3mm39_v1_chr1_+_42734889_42734937-0.123.1e-01Click!

Activity profile of Pou3f3 motif

Sorted Z-values of Pou3f3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou3f3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_+_67004178 4.19 ENSMUST00000239009.2
ENSMUST00000238912.2
Xirp2
xin actin-binding repeat containing 2
chr3_-_122828592 3.43 ENSMUST00000029761.14
Myoz2
myozenin 2
chr15_-_42540363 2.89 ENSMUST00000022921.7
Angpt1
angiopoietin 1
chr3_+_83673606 2.79 ENSMUST00000029625.8
Sfrp2
secreted frizzled-related protein 2
chr5_+_66833434 2.07 ENSMUST00000031131.11
Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr11_-_99134885 2.02 ENSMUST00000103132.10
ENSMUST00000038214.7
Krt222
keratin 222
chr4_-_149221998 1.51 ENSMUST00000176124.8
ENSMUST00000177408.2
ENSMUST00000105695.2
Cenps
centromere protein S
chr4_-_149222057 1.42 ENSMUST00000030813.10
Cenps
centromere protein S
chr4_+_134238310 1.20 ENSMUST00000105866.3
Aunip
aurora kinase A and ninein interacting protein
chr15_-_83949528 1.17 ENSMUST00000156187.8
Efcab6
EF-hand calcium binding domain 6
chr5_-_74226394 1.08 ENSMUST00000145016.3
Usp46
ubiquitin specific peptidase 46
chr3_-_133250889 0.92 ENSMUST00000197118.5
Tet2
tet methylcytosine dioxygenase 2
chr6_-_101176147 0.85 ENSMUST00000239140.2
Pdzrn3
PDZ domain containing RING finger 3
chr6_+_129326927 0.81 ENSMUST00000065289.6
Clec12a
C-type lectin domain family 12, member a
chr3_-_145813802 0.75 ENSMUST00000160285.2
Dnai3
dynein axonemal intermediate chain 3
chr3_+_92223927 0.52 ENSMUST00000061038.4
Sprr2b
small proline-rich protein 2B
chr2_-_30249202 0.48 ENSMUST00000100215.11
ENSMUST00000113620.10
ENSMUST00000163668.3
ENSMUST00000028214.15
ENSMUST00000113621.10
Sh3glb2
SH3-domain GRB2-like endophilin B2
chr1_+_43571536 0.44 ENSMUST00000202540.2
Nck2
non-catalytic region of tyrosine kinase adaptor protein 2
chr8_-_106022676 0.34 ENSMUST00000057855.4
Exoc3l
exocyst complex component 3-like
chr2_+_110551927 0.31 ENSMUST00000111017.9
Muc15
mucin 15
chr7_-_126391657 0.27 ENSMUST00000032936.8
Ppp4c
protein phosphatase 4, catalytic subunit
chr7_-_126391388 0.24 ENSMUST00000206570.2
Ppp4c
protein phosphatase 4, catalytic subunit
chr2_+_164664920 0.24 ENSMUST00000132282.2
Zswim1
zinc finger SWIM-type containing 1
chr2_-_154214622 0.16 ENSMUST00000028990.10
ENSMUST00000109730.3
Cdk5rap1
CDK5 regulatory subunit associated protein 1
chr6_+_96092230 0.14 ENSMUST00000075080.6
Tafa1
TAFA chemokine like family member 1
chr13_+_21906214 0.13 ENSMUST00000224651.2
H2bc14
H2B clustered histone 14
chr2_+_110551976 0.06 ENSMUST00000090332.5
Muc15
mucin 15
chr7_-_106408041 0.05 ENSMUST00000214840.2
Olfr700
olfactory receptor 700
chr5_-_66672158 0.01 ENSMUST00000161879.8
ENSMUST00000159357.8
Apbb2
amyloid beta (A4) precursor protein-binding, family B, member 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:2000041 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.7 2.9 GO:0030210 heparin biosynthetic process(GO:0030210)
0.3 2.1 GO:0007412 axon target recognition(GO:0007412)
0.2 0.9 GO:0019858 cytosine metabolic process(GO:0019858)
0.2 2.9 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 0.4 GO:1903898 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.1 1.1 GO:0050862 adult feeding behavior(GO:0008343) positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.2 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 4.2 GO:0003281 ventricular septum development(GO:0003281)
0.0 3.4 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.5 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.5 GO:0031424 keratinization(GO:0031424)
0.0 0.8 GO:0007528 neuromuscular junction development(GO:0007528)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.5 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 4.2 GO:0031941 filamentous actin(GO:0031941)
0.0 2.9 GO:0005902 microvillus(GO:0005902)
0.0 3.4 GO:0030018 Z disc(GO:0030018)
0.0 2.0 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0000145 exocyst(GO:0000145)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.4 GO:0051373 FATZ binding(GO:0051373)
0.5 2.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.3 2.8 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 2.9 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.9 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.5 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 4.2 GO:0051393 alpha-actinin binding(GO:0051393)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 2.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis