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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Pou3f4

Z-value: 1.24

Motif logo

Transcription factors associated with Pou3f4

Gene Symbol Gene ID Gene Info
ENSMUSG00000056854.5 Pou3f4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pou3f4mm39_v1_chrX_+_109857866_1098578860.772.4e-15Click!

Activity profile of Pou3f4 motif

Sorted Z-values of Pou3f4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou3f4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_-_99134885 11.73 ENSMUST00000103132.10
ENSMUST00000038214.7
keratin 222
chr2_-_79959178 11.41 ENSMUST00000102654.11
ENSMUST00000102655.10
phosphodiesterase 1A, calmodulin-dependent
chr2_-_66271097 10.59 ENSMUST00000112371.9
ENSMUST00000138910.3
sodium channel, voltage-gated, type I, alpha
chr1_-_132318039 10.59 ENSMUST00000132435.2
transmembrane and coiled-coil domains 2
chr15_+_92059224 10.35 ENSMUST00000068378.6
contactin 1
chr10_+_79650496 10.15 ENSMUST00000218857.2
ENSMUST00000220365.2
paralemmin
chr8_+_13034245 10.11 ENSMUST00000110873.10
ENSMUST00000173006.8
ENSMUST00000145067.8
mcf.2 transforming sequence-like
chr11_+_92989229 9.56 ENSMUST00000107859.8
ENSMUST00000107861.8
ENSMUST00000042943.13
ENSMUST00000107858.9
carbonic anhydrase 10
chr3_+_67799510 8.56 ENSMUST00000063263.5
ENSMUST00000182006.4
IQ motif containing J
Iqcj and Schip1 fusion protein
chr6_+_21215472 8.50 ENSMUST00000081542.6
potassium voltage-gated channel, Shal-related family, member 2
chr10_-_63926044 8.48 ENSMUST00000105439.2
leucine rich repeat transmembrane neuronal 3
chr10_+_90412114 8.36 ENSMUST00000182427.8
ENSMUST00000182053.8
ENSMUST00000182113.8
ankyrin repeat and sterile alpha motif domain containing 1B
chr12_-_72283465 8.04 ENSMUST00000021497.16
ENSMUST00000137990.2
reticulon 1
chr11_-_99313078 7.98 ENSMUST00000017741.4
keratin 12
chr1_-_38937190 7.92 ENSMUST00000193435.6
ENSMUST00000194361.6
carbohydrate sulfotransferase 10
chr13_+_93441307 7.90 ENSMUST00000080127.12
homer scaffolding protein 1
chr14_+_27598021 7.71 ENSMUST00000211684.2
ENSMUST00000210924.2
ELKS/RAB6-interacting/CAST family member 2
chr9_+_113641615 7.61 ENSMUST00000111838.10
ENSMUST00000166734.10
ENSMUST00000214522.2
ENSMUST00000163895.3
CLIP associating protein 2
chr1_+_66360865 7.47 ENSMUST00000114013.8
microtubule-associated protein 2
chr4_+_15881256 7.36 ENSMUST00000029876.2
calbindin 1
chr7_+_113365235 7.23 ENSMUST00000046687.16
spondin 1, (f-spondin) extracellular matrix protein
chr8_+_94537910 7.16 ENSMUST00000138659.9
guanine nucleotide binding protein, alpha O
chr11_+_92990110 7.13 ENSMUST00000107863.4
carbonic anhydrase 10
chr6_+_96090127 6.89 ENSMUST00000122120.8
TAFA chemokine like family member 1
chr11_+_71640739 6.58 ENSMUST00000150531.2
WSC domain containing 1
chr1_+_179788675 6.57 ENSMUST00000076687.12
ENSMUST00000097450.10
ENSMUST00000212756.2
CDC42 binding protein kinase alpha
chr1_-_38937170 6.53 ENSMUST00000193441.6
carbohydrate sulfotransferase 10
chr18_+_37453427 6.51 ENSMUST00000078271.4
protocadherin beta 5
chr16_+_94225942 6.45 ENSMUST00000141176.2
tetratricopeptide repeat domain 3
chr3_+_102641822 6.36 ENSMUST00000029451.12
tetraspanin 2
chr15_+_30457772 6.22 ENSMUST00000228282.2
catenin (cadherin associated protein), delta 2
chr10_-_127025851 6.22 ENSMUST00000222006.2
ENSMUST00000019611.15
ENSMUST00000219245.2
Rho guanine nucleotide exchange factor (GEF) 25
chr1_-_38937061 6.18 ENSMUST00000027249.12
carbohydrate sulfotransferase 10
chr2_-_79959802 6.04 ENSMUST00000102653.8
phosphodiesterase 1A, calmodulin-dependent
chr13_-_91053440 5.78 ENSMUST00000109541.4
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr11_-_12362136 5.76 ENSMUST00000174874.8
cordon-bleu WH2 repeat
chr3_-_116047148 5.63 ENSMUST00000090473.7
G-protein coupled receptor 88
chr7_-_66915756 5.61 ENSMUST00000207715.2
myocyte enhancer factor 2A
chr4_-_41569500 5.55 ENSMUST00000108049.9
ENSMUST00000108052.10
ENSMUST00000108050.2
family with sequence similarity 219, member A
chr13_+_42834989 5.54 ENSMUST00000149235.8
phosphatase and actin regulator 1
chr15_+_18819033 5.39 ENSMUST00000166873.9
cadherin 10
chr8_-_72178340 5.25 ENSMUST00000153800.8
ENSMUST00000146100.8
FCH domain only 1
chr5_-_52723607 5.22 ENSMUST00000199942.5
leucine-rich repeat LGI family, member 2
chr8_+_63404228 5.16 ENSMUST00000118003.8
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chr18_+_37072232 5.13 ENSMUST00000115662.9
ENSMUST00000195590.2
protocadherin alpha 2
chr2_-_120075639 4.93 ENSMUST00000090071.5
phospholipase A2, group IVE
chr5_-_52723700 4.89 ENSMUST00000039750.7
leucine-rich repeat LGI family, member 2
chr3_+_68479578 4.72 ENSMUST00000170788.9
schwannomin interacting protein 1
chr4_-_138053545 4.60 ENSMUST00000105817.4
PTEN induced putative kinase 1
chr6_-_102441628 4.59 ENSMUST00000032159.7
contactin 3
chr15_-_100497863 4.57 ENSMUST00000073837.13
POU domain, class 6, transcription factor 1
chr5_+_57876401 4.57 ENSMUST00000094783.7
protocadherin 7
chr15_-_53765869 4.51 ENSMUST00000078673.14
sterile alpha motif domain containing 12
chr4_-_110144676 4.47 ENSMUST00000106598.8
ENSMUST00000102723.11
ENSMUST00000153906.2
ELAV like RNA binding protein 4
chr11_+_87469211 4.42 ENSMUST00000107962.8
ENSMUST00000122067.8
septin 4
chr2_+_87610895 4.42 ENSMUST00000215394.2
olfactory receptor 152
chr5_-_123804745 4.40 ENSMUST00000149410.2
CAP-GLY domain containing linker protein 1
chr8_+_63404395 4.39 ENSMUST00000119068.8
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chr1_-_25868592 4.33 ENSMUST00000135518.8
adhesion G protein-coupled receptor B3
chr3_-_19749489 4.29 ENSMUST00000061294.5
corticotropin releasing hormone
chr18_+_37637317 4.29 ENSMUST00000052179.8
protocadherin beta 20
chr4_-_138053603 4.18 ENSMUST00000030536.13
PTEN induced putative kinase 1
chr7_+_100435548 4.12 ENSMUST00000216021.2
family with sequence similarity 168, member A
chr11_-_99280177 4.02 ENSMUST00000103131.5
keratin 10
chr9_-_58109564 3.95 ENSMUST00000163897.8
ENSMUST00000215950.2
immunoglobulin superfamily containing leucine-rich repeat 2
chr3_+_105881027 3.88 ENSMUST00000000573.9
oviductal glycoprotein 1
chr3_-_33136153 3.86 ENSMUST00000108225.10
peroxisomal biogenesis factor 5-like
chr18_+_37544717 3.74 ENSMUST00000051126.4
protocadherin beta 10
chr11_+_29668563 3.73 ENSMUST00000060992.6
reticulon 4
chr2_+_67004178 3.71 ENSMUST00000239009.2
ENSMUST00000238912.2
xin actin-binding repeat containing 2
chr5_-_74226394 3.66 ENSMUST00000145016.3
ubiquitin specific peptidase 46
chr14_+_10123804 3.57 ENSMUST00000022262.6
ENSMUST00000224714.2
Fez family zinc finger 2
chr13_+_93440572 3.56 ENSMUST00000109493.9
homer scaffolding protein 1
chr2_-_26184450 3.53 ENSMUST00000217256.2
ENSMUST00000227200.2
coiled-coil domain containing 187
chr12_+_103564479 3.47 ENSMUST00000190151.2
protein phosphatase 4, regulatory subunit 4
chrX_-_42256694 3.38 ENSMUST00000115058.8
ENSMUST00000115059.8
teneurin transmembrane protein 1
chr16_-_22258469 3.35 ENSMUST00000079601.13
ets variant 5
chr10_+_127226180 3.10 ENSMUST00000077046.12
ENSMUST00000105250.9
R3H domain containing 2
chr10_-_57408512 3.08 ENSMUST00000169122.8
serine incorporator 1
chr5_+_114427227 2.93 ENSMUST00000169347.6
myosin 1H
chr1_+_179788037 2.92 ENSMUST00000097453.9
ENSMUST00000111117.8
CDC42 binding protein kinase alpha
chr4_-_36056726 2.87 ENSMUST00000108124.4
leucine rich repeat and Ig domain containing 2
chr15_+_100768806 2.86 ENSMUST00000201549.4
ENSMUST00000108908.6
sodium channel, voltage-gated, type VIII, alpha
chr15_+_100768776 2.86 ENSMUST00000108909.9
sodium channel, voltage-gated, type VIII, alpha
chr16_-_22258320 2.73 ENSMUST00000170393.2
ets variant 5
chrX_+_152506577 2.72 ENSMUST00000140575.8
ENSMUST00000208373.2
ENSMUST00000185492.7
ENSMUST00000149514.8
negative regulator of P-body association
chr10_-_75946790 2.60 ENSMUST00000120757.2
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr13_+_83720484 2.45 ENSMUST00000196207.5
myocyte enhancer factor 2C
chrX_-_87159237 2.41 ENSMUST00000113966.8
ENSMUST00000113964.2
interleukin 1 receptor accessory protein-like 1
chr19_-_57227742 2.40 ENSMUST00000111559.8
actin-binding LIM protein 1
chr4_+_42114817 2.40 ENSMUST00000098123.4
predicted gene 13304
chr15_+_100768551 2.37 ENSMUST00000082209.13
sodium channel, voltage-gated, type VIII, alpha
chr4_+_41903610 2.36 ENSMUST00000098128.4
chemokine (C-C motif) ligand 21D
chr4_+_42255693 2.22 ENSMUST00000178864.3
chemokine (C-C motif) ligand 21B (leucine)
chr3_+_68776884 2.14 ENSMUST00000054551.3
RIKEN cDNA 1110032F04 gene
chr9_-_105398346 2.12 ENSMUST00000176770.8
ENSMUST00000085133.13
ATPase, Ca++-sequestering
chr18_+_57601541 2.10 ENSMUST00000091892.4
ENSMUST00000209782.2
cortexin 3
chr7_-_12552764 2.04 ENSMUST00000108546.2
ENSMUST00000072222.8
zinc finger protein 329
chr11_-_73215442 2.01 ENSMUST00000021119.9
aspartoacylase
chr12_-_72964646 2.00 ENSMUST00000044000.12
RIKEN cDNA 4930447C04 gene
chr7_-_85895409 1.97 ENSMUST00000165771.2
ENSMUST00000233075.2
ENSMUST00000233317.2
ENSMUST00000233312.2
ENSMUST00000233928.2
ENSMUST00000232799.2
ENSMUST00000233744.2
vomeronasal 2, receptor 76
chr4_+_41569775 1.95 ENSMUST00000102963.10
dynein axonemal intermediate chain 1
chr11_-_50732373 1.83 ENSMUST00000109133.2
ENSMUST00000109134.8
ENSMUST00000049625.2
zinc finger protein 879
chr10_-_38998272 1.81 ENSMUST00000136546.8
family with sequence similarity 229, member B
chr7_+_107702486 1.79 ENSMUST00000104917.4
olfactory receptor 483
chr2_+_67276338 1.79 ENSMUST00000239060.2
ENSMUST00000028410.4
ENSMUST00000112347.8
ENSMUST00000238878.2
xin actin-binding repeat containing 2
chr15_+_100768507 1.72 ENSMUST00000201518.4
ENSMUST00000200933.4
sodium channel, voltage-gated, type VIII, alpha
chr7_-_103320398 1.70 ENSMUST00000062144.4
olfactory receptor 624
chr2_+_81883566 1.62 ENSMUST00000047527.8
zinc finger protein 804A
chr12_-_59108211 1.56 ENSMUST00000217863.2
ENSMUST00000021380.10
trafficking protein particle complex 6B
chr3_-_63391300 1.51 ENSMUST00000192926.2
small transmembrane regulator of ion transport 1
chr17_+_18269686 1.49 ENSMUST00000176802.3
vomeronasal 2, receptor 124
chr3_-_126918491 1.39 ENSMUST00000238781.2
ankyrin 2, brain
chr6_-_145156517 1.29 ENSMUST00000111728.8
ENSMUST00000204105.2
ENSMUST00000060797.10
cancer susceptibility candidate 1
chr10_+_97482946 1.29 ENSMUST00000105285.4
epiphycan
chr2_-_88990751 1.25 ENSMUST00000216833.2
ENSMUST00000216976.2
olfactory receptor 1224, pseudogene 1
chr6_-_113696809 1.23 ENSMUST00000203770.3
ENSMUST00000064993.8
ghrelin
chr15_-_81074921 1.23 ENSMUST00000131235.9
ENSMUST00000134469.9
ENSMUST00000239114.2
ENSMUST00000149582.8
myocardin related transcription factor A
chr2_+_173579285 1.22 ENSMUST00000067530.6
vesicle-associated membrane protein, associated protein B and C
chr11_+_93934940 1.22 ENSMUST00000132079.8
sperm associated antigen 9
chr1_+_106866678 1.20 ENSMUST00000112724.3
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 12
chr18_+_44237474 1.11 ENSMUST00000081271.7
serine peptidase inhibitor, Kazal type 12
chr7_-_5041427 1.09 ENSMUST00000062428.5
zinc finger protein 784
chr8_+_107662352 1.09 ENSMUST00000212524.2
ENSMUST00000047425.5
syntrophin, basic 2
chr11_-_74615496 1.08 ENSMUST00000021091.15
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr6_-_101176147 1.08 ENSMUST00000239140.2
PDZ domain containing RING finger 3
chr5_-_146157711 1.08 ENSMUST00000169407.9
ENSMUST00000161331.8
ENSMUST00000159074.3
ENSMUST00000067837.10
ring finger protein (C3H2C3 type) 6
chr8_+_11808349 1.06 ENSMUST00000074856.13
ENSMUST00000098938.9
Rho guanine nucleotide exchange factor (GEF7)
chr7_+_92390811 1.05 ENSMUST00000032879.15
RAB30, member RAS oncogene family
chr4_+_136150835 1.01 ENSMUST00000088677.5
ENSMUST00000121571.8
ENSMUST00000117699.2
5-hydroxytryptamine (serotonin) receptor 1D
chr18_+_65831324 0.99 ENSMUST00000115097.8
ENSMUST00000117694.2
ENSMUST00000235962.2
O-acyltransferase like
chr9_-_58109627 0.99 ENSMUST00000216231.2
immunoglobulin superfamily containing leucine-rich repeat 2
chr5_-_108943211 0.95 ENSMUST00000004943.2
transmembrane p24 trafficking protein 11
chr14_-_96756503 0.88 ENSMUST00000022666.9
kelch-like 1
chr9_+_19533591 0.82 ENSMUST00000215372.2
zinc finger protein 317
chr18_+_22478146 0.80 ENSMUST00000120223.8
ENSMUST00000097655.4
ASXL transcriptional regulator 3
chr17_+_87270707 0.78 ENSMUST00000139344.2
ras homolog family member Q
chr7_+_86564302 0.77 ENSMUST00000233033.2
ENSMUST00000170835.4
vomeronasal 2, receptor 78
chr13_-_23372145 0.74 ENSMUST00000228239.2
ENSMUST00000227950.2
ENSMUST00000226651.2
ENSMUST00000227679.2
ENSMUST00000228854.2
vomeronasal 1 receptor 220
chr10_+_57521958 0.70 ENSMUST00000177473.8
protein kinase inhibitor beta, cAMP dependent, testis specific
chr7_-_48105989 0.68 ENSMUST00000188918.2
MAS-related GPR, member B1
chr9_-_58109526 0.66 ENSMUST00000216297.2
immunoglobulin superfamily containing leucine-rich repeat 2
chr17_+_87270504 0.65 ENSMUST00000024956.15
ras homolog family member Q
chr9_+_19533374 0.63 ENSMUST00000213725.2
ENSMUST00000208694.2
zinc finger protein 317
chr2_+_110551927 0.60 ENSMUST00000111017.9
mucin 15
chr4_+_13784749 0.60 ENSMUST00000098256.4
RUNX1 translocation partner 1
chr17_-_59298338 0.59 ENSMUST00000025064.14
PDZ and pleckstrin homology domains 1
chr7_-_90125178 0.59 ENSMUST00000032843.9
transmembrane protein 126B
chr4_+_155048571 0.57 ENSMUST00000030931.11
ENSMUST00000070953.11
pantothenate kinase 4
chr11_+_93935021 0.56 ENSMUST00000075695.13
ENSMUST00000092777.11
sperm associated antigen 9
chr2_+_30254239 0.53 ENSMUST00000077977.14
ENSMUST00000140075.9
ENSMUST00000142801.8
ENSMUST00000100214.10
mitoguardin 2
chrX_-_153362356 0.48 ENSMUST00000101137.3
spermatogenesis associated multipass transmembrane protein 2
chr17_-_22127073 0.48 ENSMUST00000106026.3
zinc finger protein 995
chr7_-_85525474 0.46 ENSMUST00000077478.8
ENSMUST00000233729.2
ENSMUST00000233079.2
ENSMUST00000233315.2
ENSMUST00000233115.2
ENSMUST00000233748.2
ENSMUST00000232965.2
ENSMUST00000232897.2
vomeronasal 2, receptor 73
chr10_+_129336682 0.46 ENSMUST00000056002.5
ENSMUST00000218901.2
olfactory receptor 790
chr2_+_154149122 0.40 ENSMUST00000088921.6
BPI fold containing family B, member 9B
chrX_+_95498965 0.40 ENSMUST00000033553.14
hephaestin
chr13_+_104424359 0.39 ENSMUST00000065766.7
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6
chr13_-_21257469 0.38 ENSMUST00000058168.2
olfactory receptor 1370
chr10_-_129509659 0.36 ENSMUST00000213294.2
ENSMUST00000216067.3
ENSMUST00000203424.2
olfactory receptor 801
chr2_-_88534814 0.35 ENSMUST00000216928.2
ENSMUST00000216977.2
olfactory receptor 1196
chr10_+_57521930 0.35 ENSMUST00000177325.8
protein kinase inhibitor beta, cAMP dependent, testis specific
chr7_+_104274001 0.33 ENSMUST00000215454.3
ENSMUST00000213297.2
olfactory receptor 657
chr8_-_86091946 0.33 ENSMUST00000034133.14
myosin light chain kinase 3
chr13_-_22686415 0.28 ENSMUST00000078642.2
vomeronasal 1 receptor 202
chr2_-_85266670 0.27 ENSMUST00000214679.2
ENSMUST00000217218.3
olfactory receptor 994
chr19_+_13211616 0.25 ENSMUST00000064102.2
olfactory receptor 1463
chr1_-_5987617 0.25 ENSMUST00000044180.5
neuropeptides B/W receptor 1
chr11_+_93935066 0.22 ENSMUST00000103168.10
sperm associated antigen 9
chr1_+_43571536 0.22 ENSMUST00000202540.2
non-catalytic region of tyrosine kinase adaptor protein 2
chr6_-_57991216 0.20 ENSMUST00000228951.2
vomeronasal 1 receptor 26
chr2_-_88600832 0.19 ENSMUST00000217588.3
olfactory receptor 1200
chr11_+_93935156 0.19 ENSMUST00000024979.15
sperm associated antigen 9
chr9_+_39722280 0.13 ENSMUST00000213975.2
olfactory receptor 970
chr17_+_36857967 0.12 ENSMUST00000041964.7
histocompatibility 2, M region locus 11
chr11_+_102775991 0.10 ENSMUST00000100369.4
family with sequence similarity 187, member A
chr6_+_66708376 0.09 ENSMUST00000077482.2
vomeronasal 1 receptor 37
chrX_+_20529137 0.08 ENSMUST00000001989.9
ubiquitin-like modifier activating enzyme 1
chr3_+_85946145 0.07 ENSMUST00000238331.2
SH3 domain protein D19
chr7_-_103217838 0.04 ENSMUST00000214806.2
olfactory receptor 616
chr7_+_101530524 0.04 ENSMUST00000106978.8
anaphase promoting complex C subunit 15
chr15_+_84076423 0.04 ENSMUST00000023071.8
SAMM50 sorting and assembly machinery component
chr11_-_69686756 0.04 ENSMUST00000045971.9
cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)
chr6_-_134864731 0.04 ENSMUST00000203762.4
ENSMUST00000215088.2
ENSMUST00000066107.10
G protein-coupled receptor 19
chr16_+_25620652 0.03 ENSMUST00000115304.8
ENSMUST00000115305.2
ENSMUST00000040231.13
ENSMUST00000115306.8
transformation related protein 63

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.4 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
1.7 10.1 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
1.5 8.8 GO:1902958 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of macromitophagy(GO:1901526) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
1.4 4.3 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
1.4 10.0 GO:0061743 motor learning(GO:0061743)
1.1 5.6 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
1.0 4.1 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.9 4.4 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.9 3.5 GO:0080163 regulation of protein serine/threonine phosphatase activity(GO:0080163)
0.8 5.8 GO:0001757 somite specification(GO:0001757)
0.8 9.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.8 6.4 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.8 17.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.8 3.9 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.8 7.6 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.8 8.4 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.8 10.6 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.7 2.0 GO:0010705 meiotic DNA double-strand break processing involved in reciprocal meiotic recombination(GO:0010705)
0.6 6.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.6 11.5 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.5 8.0 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.5 2.1 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.5 3.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797) cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.5 3.9 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.4 3.1 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.4 8.5 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.4 3.7 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.4 20.6 GO:0007616 long-term memory(GO:0007616)
0.3 10.6 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.3 1.2 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) negative regulation by virus of viral protein levels in host cell(GO:0046725)
0.3 2.0 GO:0006083 acetate metabolic process(GO:0006083)
0.3 2.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.3 4.3 GO:0008343 adult feeding behavior(GO:0008343)
0.2 18.3 GO:0019228 neuronal action potential(GO:0019228)
0.2 4.0 GO:0003334 keratinocyte development(GO:0003334)
0.2 2.4 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2 10.0 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.2 2.6 GO:1904659 glucose transmembrane transport(GO:1904659)
0.2 10.6 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.2 4.7 GO:0001553 luteinization(GO:0001553)
0.2 2.4 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.2 7.2 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.2 7.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.2 1.4 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.2 1.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.2 4.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 3.5 GO:0034453 microtubule anchoring(GO:0034453)
0.1 10.4 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.1 1.0 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.1 6.2 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.1 4.9 GO:0009395 phospholipid catabolic process(GO:0009395)
0.1 5.6 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 6.5 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 17.4 GO:0007416 synapse assembly(GO:0007416)
0.1 1.1 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.1 5.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 3.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 1.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 1.4 GO:1903077 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.2 GO:1903898 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.0 0.3 GO:0060298 regulation of vascular permeability involved in acute inflammatory response(GO:0002528) positive regulation of sarcomere organization(GO:0060298)
0.0 4.4 GO:0003281 ventricular septum development(GO:0003281)
0.0 4.5 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 1.7 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.0 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482) cloacal septation(GO:0060197) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
0.0 0.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 2.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 3.3 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.9 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 2.3 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.6 GO:1903754 cortical microtubule plus-end(GO:1903754) cytoplasmic microtubule plus-end(GO:1904511)
0.8 7.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.8 20.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.8 10.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.8 3.9 GO:0030312 external encapsulating structure(GO:0030312)
0.7 8.8 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.6 5.8 GO:1990357 terminal web(GO:1990357)
0.5 3.9 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.4 4.4 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.3 4.5 GO:0042788 polysomal ribosome(GO:0042788)
0.3 8.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 4.3 GO:0043083 synaptic cleft(GO:0043083)
0.2 12.8 GO:0043034 costamere(GO:0043034)
0.2 8.0 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.2 23.7 GO:0005882 intermediate filament(GO:0005882)
0.2 2.0 GO:0000801 central element(GO:0000801)
0.2 4.3 GO:0043196 varicosity(GO:0043196)
0.1 7.7 GO:0048786 presynaptic active zone(GO:0048786)
0.1 3.7 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 17.4 GO:0042641 actomyosin(GO:0042641)
0.1 1.1 GO:0000322 storage vacuole(GO:0000322)
0.1 7.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.1 GO:0000235 astral microtubule(GO:0000235)
0.1 10.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 1.6 GO:0030008 TRAPP complex(GO:0030008)
0.1 14.9 GO:0031225 anchored component of membrane(GO:0031225)
0.1 7.4 GO:0043195 terminal bouton(GO:0043195)
0.1 4.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.6 GO:0016459 myosin complex(GO:0016459)
0.0 6.4 GO:0043209 myelin sheath(GO:0043209)
0.0 6.9 GO:0030016 myofibril(GO:0030016)
0.0 1.0 GO:0005801 cis-Golgi network(GO:0005801)
0.0 6.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 21.2 GO:0005887 integral component of plasma membrane(GO:0005887)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.9 20.6 GO:0016232 HNK-1 sulfotransferase activity(GO:0016232)
1.7 8.5 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
1.6 17.5 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
1.4 10.1 GO:0031750 D3 dopamine receptor binding(GO:0031750)
1.1 4.3 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
1.0 8.8 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.9 7.4 GO:0005499 vitamin D binding(GO:0005499)
0.9 7.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.9 11.5 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.8 7.5 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.7 2.0 GO:0019807 aspartoacylase activity(GO:0019807)
0.7 20.4 GO:0031402 sodium ion binding(GO:0031402)
0.6 3.9 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.5 2.1 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.4 7.6 GO:0002162 dystroglycan binding(GO:0002162)
0.4 9.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.4 3.9 GO:0004568 chitinase activity(GO:0004568)
0.4 1.2 GO:0033149 FFAT motif binding(GO:0033149)
0.3 10.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.3 5.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 3.1 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.2 0.7 GO:0031768 ghrelin receptor binding(GO:0031768)
0.2 1.1 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.2 2.6 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 4.9 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 5.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 2.2 GO:0048273 MAP-kinase scaffold activity(GO:0005078) mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 5.8 GO:0003785 actin monomer binding(GO:0003785)
0.1 4.5 GO:0017091 AU-rich element binding(GO:0017091)
0.1 1.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 5.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 2.4 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 6.6 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 5.5 GO:0051393 alpha-actinin binding(GO:0051393)
0.1 1.4 GO:0005522 profilin binding(GO:0005522)
0.1 5.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.0 GO:0051378 serotonin binding(GO:0051378)
0.1 8.6 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 7.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.7 GO:0008009 chemokine activity(GO:0008009)
0.0 2.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 7.2 GO:0003774 motor activity(GO:0003774)
0.0 3.5 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.9 GO:0042923 neuropeptide binding(GO:0042923)
0.0 6.6 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.4 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 3.7 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.4 GO:0030507 spectrin binding(GO:0030507)
0.0 9.5 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 19.8 GO:0005198 structural molecule activity(GO:0005198)
0.0 1.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 1.1 GO:0050681 androgen receptor binding(GO:0050681)
0.0 5.9 GO:0030246 carbohydrate binding(GO:0030246)
0.0 3.5 GO:0008017 microtubule binding(GO:0008017)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 1.3 GO:0005550 pheromone binding(GO:0005550)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.3 17.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.2 9.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 5.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 8.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 10.0 PID NOTCH PATHWAY Notch signaling pathway
0.1 4.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 6.2 PID LKB1 PATHWAY LKB1 signaling events
0.1 9.5 PID CDC42 PATHWAY CDC42 signaling events
0.1 15.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 3.7 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 2.2 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 3.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 17.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.2 10.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 9.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 8.1 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 5.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 7.2 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 8.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.0 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 2.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 4.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 3.7 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 1.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 2.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 2.3 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events