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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Pou4f3

Z-value: 0.50

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Transcription factors associated with Pou4f3

Gene Symbol Gene ID Gene Info
Pou4f3
ENSMUSG00000024497.5 Pou4f3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pou4f3mm39_v1_chr18_+_42527604_42527640-0.191.0e-01Click!

Activity profile of Pou4f3 motif

Sorted Z-values of Pou4f3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou4f3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_+_172994841 4.11 ENSMUST00000029017.6
Pck1
phosphoenolpyruvate carboxykinase 1, cytosolic
chr13_+_24023428 3.60 ENSMUST00000091698.12
ENSMUST00000110422.3
ENSMUST00000166467.9
Slc17a3
solute carrier family 17 (sodium phosphate), member 3
chr18_-_68562385 2.69 ENSMUST00000052347.8
Mc2r
melanocortin 2 receptor
chr13_+_24023386 2.57 ENSMUST00000039721.14
Slc17a3
solute carrier family 17 (sodium phosphate), member 3
chr9_-_99302205 2.36 ENSMUST00000123771.2
Mras
muscle and microspikes RAS
chr13_-_56444118 2.27 ENSMUST00000224801.2
Cxcl14
chemokine (C-X-C motif) ligand 14
chr12_-_25147139 2.17 ENSMUST00000221761.2
Id2
inhibitor of DNA binding 2
chr2_-_140513320 2.10 ENSMUST00000056760.4
Flrt3
fibronectin leucine rich transmembrane protein 3
chr9_-_15212849 1.96 ENSMUST00000034414.10
4931406C07Rik
RIKEN cDNA 4931406C07 gene
chr19_+_29902506 1.83 ENSMUST00000120388.9
ENSMUST00000144528.8
ENSMUST00000177518.8
Il33
interleukin 33
chr1_+_139429430 1.70 ENSMUST00000027615.7
F13b
coagulation factor XIII, beta subunit
chr9_-_15212745 1.59 ENSMUST00000217042.2
4931406C07Rik
RIKEN cDNA 4931406C07 gene
chr9_+_21634779 1.44 ENSMUST00000034713.9
Ldlr
low density lipoprotein receptor
chr18_+_23886765 1.34 ENSMUST00000115830.8
Mapre2
microtubule-associated protein, RP/EB family, member 2
chrX_+_70860378 1.33 ENSMUST00000114575.4
Vma21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr14_-_73613385 1.32 ENSMUST00000227454.2
Itm2b
integral membrane protein 2B
chr12_-_103660916 1.31 ENSMUST00000117053.8
Serpina1f
serine (or cysteine) peptidase inhibitor, clade A, member 1F
chr17_+_7246365 1.30 ENSMUST00000232245.2
Rnaset2b
ribonuclease T2B
chrX_+_70860357 1.27 ENSMUST00000114576.9
Vma21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr10_+_101994841 1.26 ENSMUST00000020039.13
Mgat4c
MGAT4 family, member C
chr17_+_7246289 1.24 ENSMUST00000179728.2
Rnaset2b
ribonuclease T2B
chr17_-_8366536 1.20 ENSMUST00000231927.2
Rnaset2a
ribonuclease T2A
chr2_+_36120438 1.13 ENSMUST00000062069.6
Ptgs1
prostaglandin-endoperoxide synthase 1
chr8_-_84184978 1.10 ENSMUST00000081506.11
Scoc
short coiled-coil protein
chr7_-_138511221 1.05 ENSMUST00000130500.8
ENSMUST00000106112.2
Bnip3
BCL2/adenovirus E1B interacting protein 3
chr10_-_76562002 1.03 ENSMUST00000001147.5
Col6a1
collagen, type VI, alpha 1
chrX_+_9751861 1.01 ENSMUST00000067529.9
ENSMUST00000086165.4
Sytl5
synaptotagmin-like 5
chr11_+_109434519 0.96 ENSMUST00000106696.2
Arsg
arylsulfatase G
chr1_-_126758369 0.89 ENSMUST00000112583.8
ENSMUST00000094609.10
Nckap5
NCK-associated protein 5
chr4_-_108158242 0.85 ENSMUST00000043616.7
Zyg11b
zyg-ll family member B, cell cycle regulator
chr11_+_114566257 0.83 ENSMUST00000045779.6
Ttyh2
tweety family member 2
chr5_-_44139099 0.81 ENSMUST00000061299.9
Fgfbp1
fibroblast growth factor binding protein 1
chr18_+_56695515 0.78 ENSMUST00000130163.8
ENSMUST00000132628.8
Phax
phosphorylated adaptor for RNA export
chr17_-_33252341 0.78 ENSMUST00000087654.5
Zfp763
zinc finger protein 763
chr6_+_41498716 0.75 ENSMUST00000070380.5
Prss2
protease, serine 2
chr5_-_44139121 0.74 ENSMUST00000199894.2
Fgfbp1
fibroblast growth factor binding protein 1
chrX_-_74423647 0.74 ENSMUST00000114085.9
F8
coagulation factor VIII
chr8_+_22329942 0.72 ENSMUST00000006745.4
Defb2
defensin beta 2
chr16_-_26345493 0.66 ENSMUST00000165687.3
Tmem207
transmembrane protein 207
chr14_+_69585036 0.65 ENSMUST00000064831.6
Entpd4
ectonucleoside triphosphate diphosphohydrolase 4
chr16_+_11224481 0.61 ENSMUST00000122168.8
Snx29
sorting nexin 29
chr10_-_95158827 0.59 ENSMUST00000220279.2
Cradd
CASP2 and RIPK1 domain containing adaptor with death domain
chr7_-_101486983 0.57 ENSMUST00000185929.2
ENSMUST00000165052.8
Inppl1
inositol polyphosphate phosphatase-like 1
chr5_-_38649291 0.54 ENSMUST00000129099.8
Slc2a9
solute carrier family 2 (facilitated glucose transporter), member 9
chr11_-_74243447 0.48 ENSMUST00000141134.2
ENSMUST00000214769.2
Olfr411
olfactory receptor 411
chr1_+_179788675 0.47 ENSMUST00000076687.12
ENSMUST00000097450.10
ENSMUST00000212756.2
Cdc42bpa
CDC42 binding protein kinase alpha
chr7_-_99629637 0.46 ENSMUST00000080817.6
Rnf169
ring finger protein 169
chr2_+_132689640 0.42 ENSMUST00000124836.8
ENSMUST00000154160.2
Crls1
cardiolipin synthase 1
chr12_-_113802603 0.41 ENSMUST00000103458.3
ENSMUST00000193652.2
Ighv5-16
immunoglobulin heavy variable 5-16
chr4_+_101843823 0.39 ENSMUST00000106914.8
Gm12789
predicted gene 12789
chr7_-_46321952 0.37 ENSMUST00000049298.15
Tph1
tryptophan hydroxylase 1
chr11_-_101066266 0.35 ENSMUST00000062759.4
Ccr10
chemokine (C-C motif) receptor 10
chr9_-_19275301 0.34 ENSMUST00000214810.2
Olfr846
olfactory receptor 846
chrX_+_94942639 0.34 ENSMUST00000082183.8
Zc3h12b
zinc finger CCCH-type containing 12B
chr4_+_63477018 0.32 ENSMUST00000077709.11
Tmem268
transmembrane protein 268
chr17_+_34866160 0.31 ENSMUST00000173984.2
Atf6b
activating transcription factor 6 beta
chr5_-_120750623 0.29 ENSMUST00000140554.2
ENSMUST00000031599.9
ENSMUST00000177800.8
Rita1
RBPJ interacting and tubulin associated 1
chr10_+_101994719 0.28 ENSMUST00000138522.8
ENSMUST00000163753.8
ENSMUST00000138016.8
Mgat4c
MGAT4 family, member C
chr17_+_34866090 0.27 ENSMUST00000015605.15
Atf6b
activating transcription factor 6 beta
chr10_+_97318223 0.26 ENSMUST00000163448.4
Dcn
decorin
chr2_-_91854844 0.25 ENSMUST00000028663.5
Creb3l1
cAMP responsive element binding protein 3-like 1
chr1_-_36982747 0.24 ENSMUST00000185964.3
Tmem131
transmembrane protein 131
chr3_-_86827664 0.23 ENSMUST00000194452.2
ENSMUST00000191752.6
Dclk2
doublecortin-like kinase 2
chr17_+_37977879 0.22 ENSMUST00000215811.2
Olfr118
olfactory receptor 118
chr9_-_19799300 0.21 ENSMUST00000079660.5
Olfr862
olfactory receptor 862
chr11_+_73851643 0.20 ENSMUST00000213134.2
ENSMUST00000216291.2
Olfr397
olfactory receptor 397
chr7_-_103394150 0.19 ENSMUST00000213906.2
Olfr629
olfactory receptor 629
chr2_-_86257093 0.17 ENSMUST00000217481.2
Olfr1062
olfactory receptor 1062
chr13_+_28200187 0.17 ENSMUST00000021779.8
Prl4a1
prolactin family 4, subfamily a, member 1
chr7_+_43077088 0.17 ENSMUST00000239023.2
Gm38999
predicted gene, 38999
chr15_+_98350469 0.17 ENSMUST00000217517.2
Olfr281
olfactory receptor 281
chr1_+_45834645 0.16 ENSMUST00000147308.2
Wdr75
WD repeat domain 75
chr2_+_85835884 0.14 ENSMUST00000111589.3
Olfr1032
olfactory receptor 1032
chr10_+_129493563 0.14 ENSMUST00000217094.2
Olfr800
olfactory receptor 800
chr13_+_19526322 0.14 ENSMUST00000184430.2
Trgj4
T cell receptor gamma joining 4
chr16_-_59169609 0.13 ENSMUST00000207927.3
Olfr206
olfactory receptor 206
chr11_+_117700479 0.12 ENSMUST00000026649.14
ENSMUST00000177131.8
ENSMUST00000120928.2
ENSMUST00000175737.2
ENSMUST00000132298.2
Syngr2
Gm20708
synaptogyrin 2
predicted gene 20708
chr19_-_12313274 0.12 ENSMUST00000208398.3
Olfr1438-ps1
olfactory receptor 1438, pseudogene 1
chr7_+_106630381 0.10 ENSMUST00000213623.2
Olfr713
olfactory receptor 713
chr5_+_13448833 0.09 ENSMUST00000137798.10
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr2_-_86589298 0.09 ENSMUST00000215991.2
ENSMUST00000217043.3
Olfr1090
olfactory receptor 1090
chr5_+_13448647 0.09 ENSMUST00000125629.8
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr10_-_129107354 0.08 ENSMUST00000204573.3
Olfr777
olfactory receptor 777
chr2_+_36958319 0.08 ENSMUST00000120704.2
Olfr360
olfactory receptor 360
chr11_-_4045343 0.07 ENSMUST00000004868.6
Mtfp1
mitochondrial fission process 1
chr1_+_109911467 0.06 ENSMUST00000172005.8
Cdh7
cadherin 7, type 2
chr5_+_87148697 0.06 ENSMUST00000031186.9
Ugt2b35
UDP glucuronosyltransferase 2 family, polypeptide B35
chr3_-_86827640 0.05 ENSMUST00000195561.6
Dclk2
doublecortin-like kinase 2
chr17_-_50401305 0.05 ENSMUST00000113195.8
Rftn1
raftlin lipid raft linker 1
chr3_-_72875187 0.04 ENSMUST00000167334.8
Sis
sucrase isomaltase (alpha-glucosidase)
chr1_-_126758520 0.03 ENSMUST00000162646.8
Nckap5
NCK-associated protein 5
chr2_+_85600147 0.03 ENSMUST00000065626.3
Olfr1013
olfactory receptor 1013
chr11_-_73290321 0.02 ENSMUST00000131253.2
ENSMUST00000120303.9
Olfr1
olfactory receptor 1
chr17_-_37472385 0.01 ENSMUST00000219235.3
Olfr93
olfactory receptor 93
chr17_-_37404764 0.01 ENSMUST00000087144.5
Olfr91
olfactory receptor 91
chr4_-_119047180 0.00 ENSMUST00000150864.3
ENSMUST00000141227.9
Ermap
erythroblast membrane-associated protein

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:0061402 glycerol biosynthetic process(GO:0006114) positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
0.7 2.2 GO:0001966 thigmotaxis(GO:0001966)
0.6 2.3 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.4 6.2 GO:0015747 urate transport(GO:0015747)
0.4 1.4 GO:0090118 regulation of phosphatidylcholine catabolic process(GO:0010899) receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) positive regulation of lysosomal protein catabolic process(GO:1905167)
0.3 1.8 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.3 1.0 GO:1902109 response to cobalt ion(GO:0032025) negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.3 0.8 GO:0051030 snRNA transport(GO:0051030)
0.2 2.1 GO:0003344 pericardium morphogenesis(GO:0003344)
0.2 2.6 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 1.3 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.2 1.1 GO:0035633 cyclooxygenase pathway(GO:0019371) maintenance of blood-brain barrier(GO:0035633)
0.2 1.6 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.7 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 1.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.6 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.2 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.1 0.8 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.4 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.4 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.6 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.7 GO:0031000 response to caffeine(GO:0031000)
0.0 1.0 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.5 GO:0046415 urate metabolic process(GO:0046415)
0.0 2.7 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)
0.0 0.5 GO:2000780 negative regulation of double-strand break repair(GO:2000780)
0.0 1.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.5 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.4 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.8 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0 0.3 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 2.4 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.2 0.6 GO:0097637 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.1 3.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.8 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 2.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.3 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.8 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.3 GO:0098644 complex of collagen trimers(GO:0098644)
0.0 1.0 GO:0005581 collagen trimer(GO:0005581)
0.0 5.7 GO:0016324 apical plasma membrane(GO:0016324)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.6 6.2 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.4 2.7 GO:0004977 melanocortin receptor activity(GO:0004977)
0.2 1.4 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 1.5 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.4 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 2.3 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.6 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.1 1.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 2.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 0.2 GO:0005148 prolactin receptor binding(GO:0005148)
0.1 2.3 GO:0008009 chemokine activity(GO:0008009)
0.1 1.0 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.8 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.8 GO:0015643 toxic substance binding(GO:0015643)
0.0 1.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.5 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.6 GO:0046030 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0 0.6 GO:0070513 death domain binding(GO:0070513)
0.0 3.7 GO:0004540 ribonuclease activity(GO:0004540)
0.0 0.4 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 1.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.1 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.4 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 1.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 3.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 1.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 2.4 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.6 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.0 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 0.7 REACTOME DEFENSINS Genes involved in Defensins
0.0 1.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 1.1 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 2.7 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.8 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane