Project

PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

Navigation
Downloads

Results for Ppard

Z-value: 1.31

Motif logo

logo of

Transcription factors associated with Ppard

Gene Symbol Gene ID Gene Info
Ppard
ENSMUSG00000002250.17 Ppard

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Ppardmm39_v1_chr17_+_28451674_28451764-0.235.2e-02Click!

Activity profile of Ppard motif

Sorted Z-values of Ppard motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Ppard

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr9_-_46146558 18.12 ENSMUST00000121916.8
ENSMUST00000034586.9
Apoc3
apolipoprotein C-III
chr10_+_3490232 14.34 ENSMUST00000019896.5
Iyd
iodotyrosine deiodinase
chr9_-_46146928 12.91 ENSMUST00000118649.8
Apoc3
apolipoprotein C-III
chr3_-_79535966 11.86 ENSMUST00000120992.8
Etfdh
electron transferring flavoprotein, dehydrogenase
chr1_+_171052623 9.47 ENSMUST00000111321.8
ENSMUST00000005824.12
ENSMUST00000111320.8
ENSMUST00000111319.2
Apoa2
apolipoprotein A-II
chr3_+_98187743 9.30 ENSMUST00000120541.8
ENSMUST00000090746.3
Hmgcs2
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2
chr1_+_139429430 9.18 ENSMUST00000027615.7
F13b
coagulation factor XIII, beta subunit
chr3_-_79536166 9.07 ENSMUST00000029386.14
Etfdh
electron transferring flavoprotein, dehydrogenase
chr2_-_103315418 9.02 ENSMUST00000111168.4
Cat
catalase
chr2_-_103315483 9.02 ENSMUST00000028610.10
Cat
catalase
chr14_+_14210932 8.87 ENSMUST00000022271.14
Acox2
acyl-Coenzyme A oxidase 2, branched chain
chr3_+_51568588 8.81 ENSMUST00000099106.10
Mgst2
microsomal glutathione S-transferase 2
chr18_+_74912268 8.51 ENSMUST00000041053.11
Acaa2
acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)
chr1_+_74448535 8.32 ENSMUST00000027366.13
Vil1
villin 1
chr3_+_51568625 7.79 ENSMUST00000159554.7
ENSMUST00000161590.4
Mgst2
microsomal glutathione S-transferase 2
chr11_-_69906171 7.63 ENSMUST00000018718.8
ENSMUST00000102574.10
Acadvl
acyl-Coenzyme A dehydrogenase, very long chain
chr11_+_98337655 7.41 ENSMUST00000019456.5
Grb7
growth factor receptor bound protein 7
chr16_+_22769822 6.76 ENSMUST00000023590.9
Hrg
histidine-rich glycoprotein
chr17_-_46749370 6.67 ENSMUST00000087012.7
Slc22a7
solute carrier family 22 (organic anion transporter), member 7
chr7_+_43093507 6.50 ENSMUST00000004729.5
ENSMUST00000206286.2
ENSMUST00000206196.2
ENSMUST00000206411.2
Etfb
electron transferring flavoprotein, beta polypeptide
chrX_+_10118544 6.42 ENSMUST00000049910.13
Otc
ornithine transcarbamylase
chr3_+_96737385 6.26 ENSMUST00000058865.14
Pdzk1
PDZ domain containing 1
chr2_-_32594156 6.15 ENSMUST00000127812.3
Fpgs
folylpolyglutamyl synthetase
chr16_+_22769844 5.80 ENSMUST00000232422.2
Hrg
histidine-rich glycoprotein
chr3_-_137837117 5.67 ENSMUST00000029805.13
Mttp
microsomal triglyceride transfer protein
chrX_+_10118600 5.44 ENSMUST00000115528.3
Otc
ornithine transcarbamylase
chr1_-_120047868 5.38 ENSMUST00000112648.8
Dbi
diazepam binding inhibitor
chr6_-_142418801 5.35 ENSMUST00000032371.8
Gys2
glycogen synthase 2
chr17_-_34247016 5.15 ENSMUST00000236627.2
ENSMUST00000237759.2
ENSMUST00000045467.14
ENSMUST00000114303.4
H2-Ke6
H2-K region expressed gene 6
chr1_+_55127110 5.07 ENSMUST00000075242.7
Hspe1
heat shock protein 1 (chaperonin 10)
chr5_-_31854942 4.95 ENSMUST00000031018.10
Rbks
ribokinase
chr8_-_58106057 4.92 ENSMUST00000034021.12
Galnt7
polypeptide N-acetylgalactosaminyltransferase 7
chr3_-_83947416 4.87 ENSMUST00000192095.6
ENSMUST00000191758.6
ENSMUST00000052342.9
Tmem131l
transmembrane 131 like
chr4_+_118286898 4.79 ENSMUST00000067896.4
Elovl1
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr17_-_46749320 4.57 ENSMUST00000233575.2
Slc22a7
solute carrier family 22 (organic anion transporter), member 7
chr2_+_162829250 4.47 ENSMUST00000018012.14
Sgk2
serum/glucocorticoid regulated kinase 2
chr15_-_102097466 4.47 ENSMUST00000023805.3
Csad
cysteine sulfinic acid decarboxylase
chr17_-_35954573 4.10 ENSMUST00000095467.4
Mucl3
mucin like 3
chr9_+_108539296 4.05 ENSMUST00000035222.6
Slc25a20
solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20
chr6_+_7844759 3.90 ENSMUST00000040159.6
C1galt1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr16_-_84632439 3.89 ENSMUST00000138279.2
Atp5j
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
chr16_-_84632513 3.84 ENSMUST00000023608.14
Atp5j
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
chr4_-_41048124 3.84 ENSMUST00000030136.13
Aqp7
aquaporin 7
chr14_+_75373766 3.75 ENSMUST00000145303.8
Lcp1
lymphocyte cytosolic protein 1
chr14_-_56339915 3.73 ENSMUST00000015583.2
Ctsg
cathepsin G
chr15_-_89310060 3.72 ENSMUST00000109313.9
Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr5_+_114284585 3.68 ENSMUST00000102582.8
Acacb
acetyl-Coenzyme A carboxylase beta
chr5_+_36622342 3.65 ENSMUST00000031099.4
Grpel1
GrpE-like 1, mitochondrial
chr2_+_162829422 3.64 ENSMUST00000117123.2
Sgk2
serum/glucocorticoid regulated kinase 2
chr16_-_84632383 3.59 ENSMUST00000114191.8
Atp5j
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
chr8_+_117822593 3.58 ENSMUST00000034308.16
ENSMUST00000176860.2
Bco1
beta-carotene oxygenase 1
chr9_-_110818679 3.51 ENSMUST00000084922.6
ENSMUST00000199891.2
Rtp3
receptor transporter protein 3
chr19_-_6899173 3.50 ENSMUST00000025906.12
ENSMUST00000239322.2
Esrra
estrogen related receptor, alpha
chr2_-_32594043 3.48 ENSMUST00000143743.2
Fpgs
folylpolyglutamyl synthetase
chr17_-_27247581 3.47 ENSMUST00000143158.3
Bak1
BCL2-antagonist/killer 1
chr4_+_59581617 3.28 ENSMUST00000107528.8
Hsdl2
hydroxysteroid dehydrogenase like 2
chr1_-_55127183 3.12 ENSMUST00000027123.15
Hspd1
heat shock protein 1 (chaperonin)
chr2_-_73741664 3.03 ENSMUST00000111996.8
ENSMUST00000018914.3
Atp5g3
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)
chr11_-_83483807 3.03 ENSMUST00000019071.4
Ccl6
chemokine (C-C motif) ligand 6
chr16_+_84631956 3.00 ENSMUST00000009120.8
Gabpa
GA repeat binding protein, alpha
chr1_+_178146689 2.93 ENSMUST00000027781.7
Cox20
cytochrome c oxidase assembly protein 20
chr1_-_55127312 2.89 ENSMUST00000127861.8
ENSMUST00000144077.3
Hspd1
heat shock protein 1 (chaperonin)
chr19_-_32038838 2.81 ENSMUST00000096119.5
Asah2
N-acylsphingosine amidohydrolase 2
chr15_-_102097387 2.80 ENSMUST00000230288.2
Csad
cysteine sulfinic acid decarboxylase
chr4_-_152213315 2.79 ENSMUST00000049305.14
Espn
espin
chr5_-_120726721 2.78 ENSMUST00000046426.10
Tpcn1
two pore channel 1
chr15_-_89309998 2.73 ENSMUST00000168376.2
Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr9_-_57169830 2.46 ENSMUST00000215298.2
1700017B05Rik
RIKEN cDNA 1700017B05 gene
chr11_-_73217298 2.39 ENSMUST00000155630.9
Aspa
aspartoacylase
chr7_+_82297803 2.38 ENSMUST00000141726.8
ENSMUST00000179489.8
ENSMUST00000039881.4
Efl1
elongation factor like GTPase 1
chr11_-_4654303 2.32 ENSMUST00000058407.6
Uqcr10
ubiquinol-cytochrome c reductase, complex III subunit X
chr19_-_6899121 2.29 ENSMUST00000173635.2
Esrra
estrogen related receptor, alpha
chr2_+_84891281 2.27 ENSMUST00000238769.2
Tnks1bp1
tankyrase 1 binding protein 1
chr19_+_37184927 2.24 ENSMUST00000024078.15
ENSMUST00000112391.8
Marchf5
membrane associated ring-CH-type finger 5
chr19_+_5754395 2.01 ENSMUST00000052448.4
Kcnk7
potassium channel, subfamily K, member 7
chr3_-_105708601 2.00 ENSMUST00000197094.5
ENSMUST00000198004.2
Rap1a
RAS-related protein 1a
chr6_+_42411469 1.98 ENSMUST00000059534.5
Tas2r126
taste receptor, type 2, member 126
chr19_-_7584468 1.83 ENSMUST00000079902.6
ENSMUST00000099729.10
ENSMUST00000159983.8
Lgals12
lectin, galactose binding, soluble 12
chr2_+_160730019 1.79 ENSMUST00000109455.9
ENSMUST00000040872.13
Lpin3
lipin 3
chr16_+_84631789 1.75 ENSMUST00000114184.8
Gabpa
GA repeat binding protein, alpha
chr9_-_107749594 1.73 ENSMUST00000183035.2
Rbm6
RNA binding motif protein 6
chr6_-_97436223 1.70 ENSMUST00000113359.8
Frmd4b
FERM domain containing 4B
chr2_-_127383332 1.67 ENSMUST00000028855.14
Prom2
prominin 2
chr9_-_108888779 1.65 ENSMUST00000061973.5
Trex1
three prime repair exonuclease 1
chr17_+_52909721 1.64 ENSMUST00000039366.11
Kcnh8
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr9_+_21914334 1.55 ENSMUST00000115331.10
Prkcsh
protein kinase C substrate 80K-H
chr9_+_45924105 1.52 ENSMUST00000126865.8
Sik3
SIK family kinase 3
chr4_+_148686985 1.50 ENSMUST00000105701.9
ENSMUST00000052060.7
Masp2
mannan-binding lectin serine peptidase 2
chr9_-_57169872 1.36 ENSMUST00000213199.2
ENSMUST00000034846.7
1700017B05Rik
RIKEN cDNA 1700017B05 gene
chr9_+_45924120 1.31 ENSMUST00000120463.9
ENSMUST00000120247.8
Sik3
SIK family kinase 3
chr9_+_21914296 1.26 ENSMUST00000003493.9
Prkcsh
protein kinase C substrate 80K-H
chr9_+_21914083 1.24 ENSMUST00000216344.2
Prkcsh
protein kinase C substrate 80K-H
chr14_+_75373915 1.23 ENSMUST00000122840.8
Lcp1
lymphocyte cytosolic protein 1
chr16_-_23339329 1.07 ENSMUST00000230040.2
ENSMUST00000229619.2
Masp1
mannan-binding lectin serine peptidase 1
chr15_-_27630724 1.06 ENSMUST00000059662.8
Otulin
OTU deubiquitinase with linear linkage specificity
chr19_+_4189786 1.05 ENSMUST00000096338.5
Gpr152
G protein-coupled receptor 152
chr16_-_91728162 1.00 ENSMUST00000139277.8
ENSMUST00000154661.8
Atp5o
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr3_-_8988854 0.87 ENSMUST00000042148.6
Mrps28
mitochondrial ribosomal protein S28
chr10_-_125164399 0.83 ENSMUST00000063318.10
Slc16a7
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr11_-_94390788 0.78 ENSMUST00000127305.2
Epn3
epsin 3
chr4_+_42969934 0.69 ENSMUST00000190902.2
ENSMUST00000030163.12
1700022I11Rik
RIKEN cDNA 1700022I11 gene
chr10_+_93983844 0.67 ENSMUST00000105290.9
Nr2c1
nuclear receptor subfamily 2, group C, member 1
chr1_-_133617824 0.67 ENSMUST00000189524.2
ENSMUST00000169295.8
Lax1
lymphocyte transmembrane adaptor 1
chr15_+_25774070 0.61 ENSMUST00000125667.3
Myo10
myosin X
chr12_-_40273173 0.59 ENSMUST00000001672.12
Ifrd1
interferon-related developmental regulator 1
chr3_+_89958940 0.56 ENSMUST00000159064.8
4933434E20Rik
RIKEN cDNA 4933434E20 gene
chr4_-_136776006 0.42 ENSMUST00000049583.8
Zbtb40
zinc finger and BTB domain containing 40
chr2_+_59314989 0.38 ENSMUST00000028369.6
Dapl1
death associated protein-like 1
chr4_+_98435155 0.24 ENSMUST00000030290.8
Patj
PATJ, crumbs cell polarity complex component
chr3_+_138911648 0.23 ENSMUST00000062306.7
Stpg2
sperm tail PG rich repeat containing 2
chr2_+_165834546 0.23 ENSMUST00000109252.8
ENSMUST00000088095.6
Ncoa3
nuclear receptor coactivator 3
chr2_+_90865958 0.21 ENSMUST00000111445.10
ENSMUST00000111446.10
ENSMUST00000050323.6
Rapsn
receptor-associated protein of the synapse
chr19_-_4189603 0.17 ENSMUST00000025761.8
Cabp4
calcium binding protein 4
chr17_+_34879431 0.10 ENSMUST00000238967.2
Tnxb
tenascin XB
chr1_+_171386752 0.08 ENSMUST00000004829.13
Cd244a
CD244 molecule A
chr1_+_74545203 0.07 ENSMUST00000087215.7
Cnot9
CCR4-NOT transcription complex, subunit 9
chr11_-_73217633 0.05 ENSMUST00000134079.2
Aspa
aspartoacylase
chr10_-_93425553 0.00 ENSMUST00000020203.7
Snrpf
small nuclear ribonucleoprotein polypeptide F

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.8 31.0 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
4.2 12.6 GO:0097037 heme export(GO:0097037)
4.0 11.9 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
3.2 9.6 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
2.4 9.5 GO:0046340 regulation of very-low-density lipoprotein particle remodeling(GO:0010901) diacylglycerol catabolic process(GO:0046340)
2.1 8.5 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
2.1 8.3 GO:1902896 terminal web assembly(GO:1902896)
2.0 6.0 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
1.8 3.7 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
1.8 43.9 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
1.5 7.3 GO:0042412 taurine biosynthetic process(GO:0042412)
1.2 4.9 GO:0006014 D-ribose metabolic process(GO:0006014)
1.2 18.0 GO:0009650 UV protection(GO:0009650)
1.1 5.4 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.9 10.3 GO:0015879 carnitine transport(GO:0015879)
0.9 3.5 GO:0010046 response to mycotoxin(GO:0010046)
0.8 3.8 GO:0015793 glycerol transport(GO:0015793) renal water absorption(GO:0070295)
0.8 14.3 GO:0006570 tyrosine metabolic process(GO:0006570)
0.7 4.9 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.7 16.6 GO:0019370 glutathione biosynthetic process(GO:0006750) leukotriene biosynthetic process(GO:0019370)
0.6 5.7 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.6 5.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.6 3.9 GO:0016266 O-glycan processing(GO:0016266)
0.5 4.7 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.5 15.4 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.4 1.7 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.4 11.2 GO:0035634 response to stilbenoid(GO:0035634)
0.4 4.8 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.4 3.7 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.3 2.8 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.3 2.4 GO:0006083 acetate metabolic process(GO:0006083)
0.3 2.4 GO:0042256 mature ribosome assembly(GO:0042256)
0.3 7.4 GO:0034063 stress granule assembly(GO:0034063)
0.3 1.6 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.2 5.1 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.2 3.6 GO:0042574 retinal metabolic process(GO:0042574)
0.2 9.3 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.2 2.0 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 5.0 GO:0051639 actin filament network formation(GO:0051639)
0.2 2.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 2.3 GO:0017062 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.2 2.9 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.1 5.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 5.8 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1 2.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 2.9 GO:0006491 N-glycan processing(GO:0006491)
0.1 4.9 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.1 6.5 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.1 5.4 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 1.1 GO:0070431 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.1 2.3 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 2.8 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.1 3.0 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 0.7 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 8.1 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 0.2 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.0 2.8 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 1.8 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.2 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 1.8 GO:0050994 regulation of lipid catabolic process(GO:0050994)
0.0 1.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 8.2 GO:0007596 blood coagulation(GO:0007596)
0.0 1.7 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.6 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 3.7 GO:0006457 protein folding(GO:0006457)
0.0 0.1 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.0 2.8 GO:0006665 sphingolipid metabolic process(GO:0006665)
0.0 0.2 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.1 GO:2000327 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.9 27.4 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
4.2 12.6 GO:0061474 phagolysosome membrane(GO:0061474)
2.8 31.0 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
1.0 15.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.9 9.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.7 6.0 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.6 2.9 GO:0017177 glucosidase II complex(GO:0017177)
0.4 1.7 GO:0044393 microspike(GO:0044393)
0.4 11.9 GO:0031528 microvillus membrane(GO:0031528)
0.3 8.3 GO:0032433 filopodium tip(GO:0032433)
0.3 3.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 1.1 GO:0071797 LUBAC complex(GO:0071797)
0.2 2.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.2 16.7 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2 2.8 GO:0032426 stereocilium tip(GO:0032426)
0.2 5.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 5.0 GO:0001891 phagocytic cup(GO:0001891)
0.1 11.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 7.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 27.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 2.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 19.7 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 5.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 14.3 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 3.8 GO:0031526 brush border membrane(GO:0031526)
0.0 6.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 16.6 GO:0005635 nuclear envelope(GO:0005635)
0.0 4.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 2.3 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 2.8 GO:0010008 endosome membrane(GO:0010008)
0.0 17.7 GO:0005739 mitochondrion(GO:0005739)
0.0 0.8 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 2.3 GO:0001726 ruffle(GO:0001726)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
10.1 40.5 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
4.8 14.3 GO:0004447 iodide peroxidase activity(GO:0004447)
4.5 18.0 GO:0004096 catalase activity(GO:0004096)
4.2 20.9 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
4.2 16.6 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
3.2 9.6 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326)
3.1 9.3 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
3.0 11.9 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
2.5 7.6 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
1.8 5.4 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
1.3 5.4 GO:0030156 benzodiazepine receptor binding(GO:0030156)
1.1 6.5 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
1.0 8.3 GO:0035727 lysophosphatidic acid binding(GO:0035727)
1.0 7.3 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
1.0 6.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.8 2.4 GO:0019807 aspartoacylase activity(GO:0019807)
0.8 6.3 GO:0005124 scavenger receptor binding(GO:0005124)
0.8 3.8 GO:0015254 glycerol channel activity(GO:0015254)
0.7 8.9 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.7 3.7 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.7 5.1 GO:0070404 NADH binding(GO:0070404)
0.7 8.5 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.7 4.1 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.6 2.8 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.5 1.8 GO:0048030 disaccharide binding(GO:0048030)
0.4 4.8 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.4 3.5 GO:0031849 olfactory receptor binding(GO:0031849)
0.4 3.9 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.4 2.8 GO:0017040 ceramidase activity(GO:0017040)
0.3 3.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.3 1.7 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.3 2.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.3 8.1 GO:0017081 chloride channel regulator activity(GO:0017081)
0.3 11.2 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.3 2.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.3 1.6 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.3 5.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.2 4.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2 4.0 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 2.0 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 3.5 GO:0051400 BH domain binding(GO:0051400)
0.1 7.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 4.9 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 11.3 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.1 3.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 11.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 3.9 GO:0009055 electron carrier activity(GO:0009055)
0.1 2.0 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.6 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 1.5 GO:0001846 opsonin binding(GO:0001846)
0.1 3.0 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 1.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 6.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 5.1 GO:0051087 chaperone binding(GO:0051087)
0.0 1.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.4 GO:0070513 death domain binding(GO:0070513)
0.0 4.7 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 2.9 GO:0005080 protein kinase C binding(GO:0005080)
0.0 8.4 GO:0051015 actin filament binding(GO:0051015)
0.0 1.7 GO:0015485 cholesterol binding(GO:0015485)
0.0 3.8 GO:0008201 heparin binding(GO:0008201)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 1.1 GO:0048306 calcium-dependent protein binding(GO:0048306)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 18.0 PID FOXO PATHWAY FoxO family signaling
0.2 14.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 3.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 5.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 9.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 5.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 9.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 28.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.8 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.6 PID NETRIN PATHWAY Netrin-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 46.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.9 18.0 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.7 11.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.7 14.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.6 12.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.5 9.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.5 14.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.4 7.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.3 16.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.3 24.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.3 7.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.3 2.6 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.3 3.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 7.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 7.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.2 2.9 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.2 3.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 4.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 8.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 2.0 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 2.0 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 9.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 12.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 4.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 11.0 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 2.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 2.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 5.4 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.1 3.5 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 11.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels