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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Pparg_Rxrg

Z-value: 3.50

Motif logo

Transcription factors associated with Pparg_Rxrg

Gene Symbol Gene ID Gene Info
ENSMUSG00000000440.13 Pparg
ENSMUSG00000015843.11 Rxrg

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Rxrgmm39_v1_chr1_+_167425953_167425978-0.113.5e-01Click!
Ppargmm39_v1_chr6_+_115339303_115339321-0.094.7e-01Click!

Activity profile of Pparg_Rxrg motif

Sorted Z-values of Pparg_Rxrg motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Pparg_Rxrg

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr9_-_46146558 57.14 ENSMUST00000121916.8
ENSMUST00000034586.9
apolipoprotein C-III
chr15_+_82336535 56.13 ENSMUST00000089129.7
ENSMUST00000229313.2
ENSMUST00000231136.2
cytochrome P450, family 2, subfamily d, polypeptide 9
chr11_-_77784922 52.33 ENSMUST00000017597.5
pipecolic acid oxidase
chr9_-_46146928 46.60 ENSMUST00000118649.8
apolipoprotein C-III
chr2_+_126398048 44.59 ENSMUST00000141482.3
solute carrier family 27 (fatty acid transporter), member 2
chr2_+_172994841 39.59 ENSMUST00000029017.6
phosphoenolpyruvate carboxykinase 1, cytosolic
chr13_+_91889626 38.79 ENSMUST00000022120.5
acyl-CoA thioesterase 12
chr7_+_26821266 37.85 ENSMUST00000206552.2
cytochrome P450, family 2, subfamily f, polypeptide 2
chr3_+_82933383 37.28 ENSMUST00000029630.15
ENSMUST00000166581.4
fibrinogen alpha chain
chr19_-_44017637 32.39 ENSMUST00000026211.10
ENSMUST00000211830.2
cytochrome P450, family 2, subfamily c, polypeptide 23
chr19_+_39275518 31.44 ENSMUST00000003137.15
cytochrome P450, family 2, subfamily c, polypeptide 29
chr3_+_94600863 31.29 ENSMUST00000090848.10
ENSMUST00000173981.8
ENSMUST00000173849.8
ENSMUST00000174223.2
selenium binding protein 2
chrX_+_149377416 30.21 ENSMUST00000112713.3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr11_-_69906171 29.95 ENSMUST00000018718.8
ENSMUST00000102574.10
acyl-Coenzyme A dehydrogenase, very long chain
chr13_-_93774469 29.80 ENSMUST00000099309.6
betaine-homocysteine methyltransferase
chr9_-_15212849 29.28 ENSMUST00000034414.10
RIKEN cDNA 4931406C07 gene
chr7_+_30193047 28.55 ENSMUST00000058280.13
ENSMUST00000133318.8
ENSMUST00000142575.8
ENSMUST00000131040.2
proline dehydrogenase (oxidase) 2
chr19_+_46120327 28.43 ENSMUST00000043739.6
ENSMUST00000237098.2
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3
chr10_+_127637015 28.19 ENSMUST00000071646.2
retinol dehydrogenase 16
chr1_+_139429430 27.73 ENSMUST00000027615.7
coagulation factor XIII, beta subunit
chr19_-_39729431 27.26 ENSMUST00000099472.4
cytochrome P450, family 2, subfamily c, polypeptide 68
chr19_-_39637489 26.26 ENSMUST00000067328.7
cytochrome P450, family 2, subfamily c, polypeptide 67
chr1_+_88334678 25.69 ENSMUST00000027518.12
secreted phosphoprotein 2
chr2_+_24970327 25.13 ENSMUST00000044078.10
ENSMUST00000114380.9
ectonucleoside triphosphate diphosphohydrolase 8
chr11_+_69945157 25.09 ENSMUST00000108585.9
ENSMUST00000018699.13
asialoglycoprotein receptor 1
chr19_-_40175709 24.90 ENSMUST00000051846.13
cytochrome P450, family 2, subfamily c, polypeptide 70
chr3_+_138121245 24.60 ENSMUST00000161312.8
ENSMUST00000013458.9
alcohol dehydrogenase 4 (class II), pi polypeptide
chr18_+_74912268 24.09 ENSMUST00000041053.11
acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)
chr2_-_32594156 23.89 ENSMUST00000127812.3
folylpolyglutamyl synthetase
chr14_+_14210932 23.72 ENSMUST00000022271.14
acyl-Coenzyme A oxidase 2, branched chain
chr10_+_128626772 23.54 ENSMUST00000219404.2
ENSMUST00000026411.8
matrix metallopeptidase 19
chr19_-_39875192 23.17 ENSMUST00000168838.3
cytochrome P450, family 2, subfamily c, polypeptide 69
chr5_-_130053120 22.83 ENSMUST00000161640.8
ENSMUST00000161884.2
ENSMUST00000161094.8
argininosuccinate lyase
chr9_-_103105638 22.57 ENSMUST00000126359.2
transferrin
chr17_-_35100980 22.08 ENSMUST00000152417.8
ENSMUST00000146299.8
complement component 2 (within H-2S)
predicted gene 20547
chr19_+_36532061 21.64 ENSMUST00000169036.9
ENSMUST00000047247.12
HECT domain E3 ubiquitin protein ligase 2
chr3_-_79535966 21.44 ENSMUST00000120992.8
electron transferring flavoprotein, dehydrogenase
chr10_+_3490232 21.39 ENSMUST00000019896.5
iodotyrosine deiodinase
chr5_-_110434026 21.36 ENSMUST00000031472.12
peroxisomal membrane protein 2
chr13_-_42000958 21.34 ENSMUST00000072012.10
androgen dependent TFPI regulating protein
chr15_-_82648376 21.28 ENSMUST00000055721.6
cytochrome P450, family 2, subfamily d, polypeptide 40
chr7_-_19415301 20.82 ENSMUST00000150569.9
ENSMUST00000127648.4
ENSMUST00000003071.10
predicted gene 44805
apolipoprotein C-IV
chr10_+_76411474 20.64 ENSMUST00000001183.8
formiminotransferase cyclodeaminase
chr7_+_140415431 20.53 ENSMUST00000209978.2
ENSMUST00000210916.2
urate (5-hydroxyiso-) hydrolase
chr15_+_82439273 20.19 ENSMUST00000229103.2
ENSMUST00000068861.8
ENSMUST00000229904.2
cytochrome P450, family 2, subfamily d, polypeptide 12
chr17_-_46749370 20.12 ENSMUST00000087012.7
solute carrier family 22 (organic anion transporter), member 7
chr3_-_153650068 19.92 ENSMUST00000150070.2
acyl-Coenzyme A dehydrogenase, medium chain
chr9_-_15212745 19.62 ENSMUST00000217042.2
RIKEN cDNA 4931406C07 gene
chr9_+_46151994 19.54 ENSMUST00000034585.7
apolipoprotein A-IV
chr19_-_8382424 19.32 ENSMUST00000064507.12
ENSMUST00000120540.2
ENSMUST00000096269.11
solute carrier family 22, member 30
chr10_-_89342493 19.13 ENSMUST00000058126.15
ENSMUST00000105296.9
nuclear receptor subfamily 1, group H, member 4
chr2_-_25390625 18.96 ENSMUST00000040042.11
complement component 8, gamma polypeptide
chr7_-_105249308 18.62 ENSMUST00000210531.2
ENSMUST00000033185.10
hemopexin
chr15_-_82678490 18.42 ENSMUST00000006094.6
cytochrome P450, family 2, subfamily d, polypeptide 26
chr17_-_35101069 18.12 ENSMUST00000025230.15
complement component 2 (within H-2S)
chr11_+_98337655 18.11 ENSMUST00000019456.5
growth factor receptor bound protein 7
chr3_-_153650269 17.71 ENSMUST00000072697.13
acyl-Coenzyme A dehydrogenase, medium chain
chr3_+_89043440 17.71 ENSMUST00000047111.13
pyruvate kinase liver and red blood cell
chr1_+_171052623 17.48 ENSMUST00000111321.8
ENSMUST00000005824.12
ENSMUST00000111320.8
ENSMUST00000111319.2
apolipoprotein A-II
chr3_+_89043879 17.46 ENSMUST00000107482.10
ENSMUST00000127058.2
pyruvate kinase liver and red blood cell
chr18_-_32271224 17.34 ENSMUST00000234657.2
ENSMUST00000234386.2
ENSMUST00000234651.2
protein C
chr15_-_82291372 16.90 ENSMUST00000230198.2
ENSMUST00000230248.2
ENSMUST00000072776.5
ENSMUST00000229911.2
cytochrome P450, family 2, subfamily d, polypeptide 10
chr3_-_79536166 16.57 ENSMUST00000029386.14
electron transferring flavoprotein, dehydrogenase
chr11_+_75358866 16.56 ENSMUST00000043598.14
ENSMUST00000108435.2
TLC domain containing 2
chr14_-_55995912 16.48 ENSMUST00000001497.9
cell death-inducing DNA fragmentation factor, alpha subunit-like effector B
chr1_+_74448535 16.27 ENSMUST00000027366.13
villin 1
chr4_-_61700450 16.26 ENSMUST00000107477.2
ENSMUST00000080606.9
major urinary protein 19
chr16_+_4825216 16.16 ENSMUST00000185147.8
small integral membrane protein 22
chr19_+_12610668 16.16 ENSMUST00000044976.12
glycine-N-acyltransferase
chrX_+_10118544 16.13 ENSMUST00000049910.13
ornithine transcarbamylase
chr8_+_13076024 16.11 ENSMUST00000033820.4
coagulation factor VII
chr9_+_46180362 16.10 ENSMUST00000214202.2
ENSMUST00000215458.2
ENSMUST00000215187.2
ENSMUST00000213878.2
ENSMUST00000034584.4
apolipoprotein A-V
chr15_+_9279915 15.82 ENSMUST00000022861.9
UDP glycosyltransferases 3 family, polypeptide A1
chr7_+_140343652 15.77 ENSMUST00000026552.9
ENSMUST00000209253.2
ENSMUST00000210235.2
cytochrome P450, family 2, subfamily e, polypeptide 1
chr7_+_43093507 15.74 ENSMUST00000004729.5
ENSMUST00000206286.2
ENSMUST00000206196.2
ENSMUST00000206411.2
electron transferring flavoprotein, beta polypeptide
chr7_-_30643444 15.37 ENSMUST00000062620.9
hepcidin antimicrobial peptide
chr11_+_4833186 15.24 ENSMUST00000139737.2
nipsnap homolog 1
chr11_-_75330302 15.24 ENSMUST00000043696.9
serine (or cysteine) peptidase inhibitor, clade F, member 2
chr11_-_75330415 15.11 ENSMUST00000128330.8
serine (or cysteine) peptidase inhibitor, clade F, member 2
chr1_-_184543367 14.74 ENSMUST00000048462.13
ENSMUST00000110992.9
mitochondrial amidoxime reducing component 1
chr12_+_108817043 14.28 ENSMUST00000057026.10
ENSMUST00000221080.2
solute carrier family 25, member 47
chr2_-_32594043 14.28 ENSMUST00000143743.2
folylpolyglutamyl synthetase
chr6_+_72575458 14.07 ENSMUST00000070597.13
ENSMUST00000176364.8
ENSMUST00000176168.3
retinol saturase (all trans retinol 13,14 reductase)
chr5_-_105387395 14.04 ENSMUST00000065588.7
guanylate-binding protein 10
chr2_-_91025441 13.96 ENSMUST00000002177.9
nuclear receptor subfamily 1, group H, member 3
chrX_+_10118600 13.56 ENSMUST00000115528.3
ornithine transcarbamylase
chr19_+_39980868 13.47 ENSMUST00000049178.3
cytochrome P450, family 2. subfamily c, polypeptide 37
chr2_-_91466739 13.45 ENSMUST00000111335.2
ENSMUST00000028681.15
coagulation factor II
chr4_+_148686985 13.24 ENSMUST00000105701.9
ENSMUST00000052060.7
mannan-binding lectin serine peptidase 2
chr10_+_59239466 13.15 ENSMUST00000009790.14
phospholipase A2, group XIIB
chr7_-_19411866 13.07 ENSMUST00000142352.9
apolipoprotein C-II
chr5_+_92719336 13.06 ENSMUST00000176621.8
ENSMUST00000175974.2
ENSMUST00000131166.9
ENSMUST00000176448.8
ENSMUST00000082382.8
family with sequence similarity 47, member E
chr10_-_127206300 12.98 ENSMUST00000026472.10
inhibin beta-C
chr2_-_91025492 12.84 ENSMUST00000111354.2
nuclear receptor subfamily 1, group H, member 3
chr16_+_4825170 12.81 ENSMUST00000178155.9
small integral membrane protein 22
chr8_+_105573693 12.68 ENSMUST00000055052.6
carboxylesterase 2C
chr11_-_78313043 12.64 ENSMUST00000001122.6
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr2_-_154445578 12.64 ENSMUST00000109703.3
ENSMUST00000000896.11
peroxisomal membrane protein 4
chr17_-_46749320 12.60 ENSMUST00000233575.2
solute carrier family 22 (organic anion transporter), member 7
chr6_+_90310252 12.52 ENSMUST00000046128.12
ENSMUST00000164761.6
urocanase domain containing 1
chr7_+_140415170 12.44 ENSMUST00000211372.2
ENSMUST00000026554.11
ENSMUST00000185612.3
urate (5-hydroxyiso-) hydrolase
chr13_-_42001075 12.43 ENSMUST00000179758.8
androgen dependent TFPI regulating protein
chr6_-_85846110 12.36 ENSMUST00000045008.8
N-acetyltransferase 8 (GCN5-related) family member 2
chr9_-_103165489 12.35 ENSMUST00000035163.10
RIKEN cDNA 1300017J02 gene
chr2_-_91025380 12.32 ENSMUST00000111356.8
nuclear receptor subfamily 1, group H, member 3
chr4_-_119515978 12.32 ENSMUST00000106309.9
ENSMUST00000044426.8
guanylate cyclase activator 2b (retina)
chr4_-_62005498 12.31 ENSMUST00000107488.4
ENSMUST00000107472.8
ENSMUST00000084531.11
major urinary protein 3
chr15_+_9335636 12.31 ENSMUST00000072403.7
UDP glycosyltransferases 3 family, polypeptide A2
chr15_-_82278223 12.28 ENSMUST00000170255.2
cytochrome P450, family 2, subfamily d, polypeptide 11
chr3_-_137837117 12.25 ENSMUST00000029805.13
microsomal triglyceride transfer protein
chr16_-_93726399 12.17 ENSMUST00000177648.8
ENSMUST00000142083.2
claudin 14
chr6_-_119365632 12.15 ENSMUST00000169744.8
adiponectin receptor 2
chr5_-_115257336 12.06 ENSMUST00000031524.11
acyl-Coenzyme A dehydrogenase, short chain
chr3_+_94840352 12.02 ENSMUST00000090839.12
selenium binding protein 1
chr10_-_128796834 12.01 ENSMUST00000026398.5
methyltransferase like 7B
chr10_+_127612243 11.89 ENSMUST00000136223.2
ENSMUST00000052652.7
retinol dehydrogenase 9
chr3_+_98187743 11.77 ENSMUST00000120541.8
ENSMUST00000090746.3
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2
chr10_+_128104525 11.73 ENSMUST00000050901.5
apolipoprotein F
chr17_-_31348576 11.70 ENSMUST00000024827.5
trefoil factor 3, intestinal
chr9_-_103165423 11.62 ENSMUST00000123530.8
RIKEN cDNA 1300017J02 gene
chr13_-_42001102 11.58 ENSMUST00000121404.8
androgen dependent TFPI regulating protein
chr15_-_102097387 11.52 ENSMUST00000230288.2
cysteine sulfinic acid decarboxylase
chr9_+_108539296 11.49 ENSMUST00000035222.6
solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20
chr7_+_140414837 11.40 ENSMUST00000106050.8
urate (5-hydroxyiso-) hydrolase
chr19_-_8109346 11.39 ENSMUST00000065651.5
solute carrier family 22, member 28
chr5_+_31454787 11.31 ENSMUST00000201166.4
ENSMUST00000072228.9
glucokinase regulatory protein
chr16_+_4825146 11.12 ENSMUST00000184439.8
small integral membrane protein 22
chr8_+_105460627 11.07 ENSMUST00000034346.15
ENSMUST00000164182.3
carboxylesterase 2A
chr9_-_55419442 10.93 ENSMUST00000034866.9
electron transferring flavoprotein, alpha polypeptide
chr10_+_127595639 10.76 ENSMUST00000128247.2
RDH16 family member 1
chr1_-_55127312 10.70 ENSMUST00000127861.8
ENSMUST00000144077.3
heat shock protein 1 (chaperonin)
chr6_+_121320008 10.57 ENSMUST00000166457.8
solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
chr6_-_142418801 10.57 ENSMUST00000032371.8
glycogen synthase 2
chr3_+_116306719 10.55 ENSMUST00000000349.11
ENSMUST00000197201.5
dihydrolipoamide branched chain transacylase E2
chr15_+_75088445 10.53 ENSMUST00000055719.8
lymphocyte antigen 6 complex, locus G2
chr4_-_103072343 10.53 ENSMUST00000150285.8
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
chr4_-_150085722 10.53 ENSMUST00000153394.2
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr9_-_22046970 10.38 ENSMUST00000165735.9
acid phosphatase 5, tartrate resistant
chr1_-_55127183 10.36 ENSMUST00000027123.15
heat shock protein 1 (chaperonin)
chr17_-_34247016 10.30 ENSMUST00000236627.2
ENSMUST00000237759.2
ENSMUST00000045467.14
ENSMUST00000114303.4
H2-K region expressed gene 6
chr7_-_14172434 10.21 ENSMUST00000210396.2
ENSMUST00000168252.9
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 8
chr1_-_136877277 10.21 ENSMUST00000168126.7
nuclear receptor subfamily 5, group A, member 2
chr5_+_114142842 10.05 ENSMUST00000161610.6
D-amino acid oxidase
chr1_-_136876902 9.92 ENSMUST00000195428.2
nuclear receptor subfamily 5, group A, member 2
chr10_-_25412010 9.89 ENSMUST00000179685.3
small leucine-rich protein 1
chr14_+_40873399 9.87 ENSMUST00000225792.2
mannose-binding lectin (protein A) 1
chr2_-_91025208 9.87 ENSMUST00000111355.8
nuclear receptor subfamily 1, group H, member 3
chr1_+_55127110 9.86 ENSMUST00000075242.7
heat shock protein 1 (chaperonin 10)
chr15_+_3300249 9.82 ENSMUST00000082424.12
ENSMUST00000159158.9
ENSMUST00000159216.10
ENSMUST00000160311.3
selenoprotein P
chr13_-_41981893 9.78 ENSMUST00000137905.2
androgen dependent TFPI regulating protein
chr4_-_60697274 9.74 ENSMUST00000117932.2
major urinary protein 12
chr1_+_88139678 9.65 ENSMUST00000073049.7
UDP glucuronosyltransferase 1 family, polypeptide A1
chr13_-_41981812 9.61 ENSMUST00000223337.2
ENSMUST00000221691.2
androgen dependent TFPI regulating protein
chr9_-_107546166 9.57 ENSMUST00000177567.8
solute carrier family 38, member 3
chr14_+_122771734 9.53 ENSMUST00000154206.8
ENSMUST00000038374.13
ENSMUST00000135578.8
propionyl-Coenzyme A carboxylase, alpha polypeptide
chr3_-_58433313 9.42 ENSMUST00000029385.9
stress-associated endoplasmic reticulum protein 1
chr10_+_87694924 9.38 ENSMUST00000095360.11
insulin-like growth factor 1
chr10_+_128089965 9.37 ENSMUST00000060782.5
ENSMUST00000218722.2
apolipoprotein N
chr5_-_38637474 9.35 ENSMUST00000143758.8
ENSMUST00000156272.8
solute carrier family 2 (facilitated glucose transporter), member 9
chr7_+_119773070 9.30 ENSMUST00000033201.7
ankyrin repeat and sterile alpha motif domain containing 4B
chr5_-_18040713 9.27 ENSMUST00000197890.5
CD36 molecule
chr5_+_120614587 9.19 ENSMUST00000201684.4
ENSMUST00000066540.14
serine dehydratase
chr4_-_115504907 9.15 ENSMUST00000102707.10
cytochrome P450, family 4, subfamily b, polypeptide 1
chr11_+_101258368 9.13 ENSMUST00000019469.3
glucose-6-phosphatase, catalytic
chr6_+_82029288 9.12 ENSMUST00000149023.2
eva-1 homolog A (C. elegans)
chr19_-_4548602 9.10 ENSMUST00000048482.8
RIKEN cDNA 2010003K11 gene
chr17_+_84990541 9.09 ENSMUST00000045714.15
ENSMUST00000171915.2
ATP binding cassette subfamily G member 8
chr2_-_69172944 9.03 ENSMUST00000102709.8
ENSMUST00000102710.10
ENSMUST00000180142.2
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr19_-_10581622 8.94 ENSMUST00000037678.7
triokinase, FMN cyclase
chr15_-_102097466 8.80 ENSMUST00000023805.3
cysteine sulfinic acid decarboxylase
chr11_+_114742619 8.79 ENSMUST00000053361.12
ENSMUST00000021071.14
ENSMUST00000136785.2
G protein-coupled receptor, family C, group 5, member C
chr16_+_31241085 8.79 ENSMUST00000089759.9
3-hydroxybutyrate dehydrogenase, type 1
chr11_+_73090270 8.76 ENSMUST00000006105.7
sedoheptulokinase
chr10_+_69048506 8.70 ENSMUST00000167384.8
Rho-related BTB domain containing 1
chr11_-_61268879 8.70 ENSMUST00000010267.10
solute carrier family 47, member 1
chr5_-_38637624 8.68 ENSMUST00000067886.12
solute carrier family 2 (facilitated glucose transporter), member 9
chr7_-_97066937 8.65 ENSMUST00000043077.8
thyroid hormone responsive
chr15_+_76579960 8.61 ENSMUST00000229679.2
glutamic pyruvic transaminase, soluble
chr5_+_114284585 8.60 ENSMUST00000102582.8
acetyl-Coenzyme A carboxylase beta
chr5_+_31078775 8.59 ENSMUST00000201621.4
ketohexokinase
chr5_-_18040647 8.56 ENSMUST00000082367.13
CD36 molecule
chr4_+_20007938 8.55 ENSMUST00000125799.8
ENSMUST00000121491.8
tocopherol (alpha) transfer protein
chr9_-_86577940 8.55 ENSMUST00000034989.15
malic enzyme 1, NADP(+)-dependent, cytosolic
chr17_-_34000804 8.47 ENSMUST00000002360.17
angiopoietin-like 4
chr17_-_84990360 8.47 ENSMUST00000066175.10
ATP binding cassette subfamily G member 5
chr13_-_63006176 8.39 ENSMUST00000021907.9
fructose bisphosphatase 2
chr11_-_89893707 8.32 ENSMUST00000020864.9
phosphatidylcholine transfer protein
chr5_+_114141894 8.31 ENSMUST00000086599.11
D-amino acid oxidase
chr1_-_180023518 8.18 ENSMUST00000162769.8
ENSMUST00000161379.2
ENSMUST00000027766.13
ENSMUST00000161814.8
coenzyme Q8A
chr9_+_65538352 8.16 ENSMUST00000216342.2
ENSMUST00000216382.2
RNA binding protein with multiple splicing 2
chr16_+_4501934 8.15 ENSMUST00000060067.12
ENSMUST00000115854.4
ENSMUST00000229529.2
DnaJ heat shock protein family (Hsp40) member A3
chr7_-_45679703 8.13 ENSMUST00000002850.8
ATP-binding cassette, sub-family C (CFTR/MRP), member 6
chr10_+_127685785 8.10 ENSMUST00000077530.3
retinol dehydrogenase 19
chr1_+_163979384 8.04 ENSMUST00000086040.6
coagulation factor V
chr15_-_100579813 8.02 ENSMUST00000230572.2
chymotrypsin-like elastase family, member 1
chr11_-_88754543 8.01 ENSMUST00000107904.3
A kinase (PRKA) anchor protein 1
chr19_-_6899173 7.95 ENSMUST00000025906.12
ENSMUST00000239322.2
estrogen related receptor, alpha
chr9_-_103099262 7.88 ENSMUST00000170904.2
transferrin
chr14_+_55716377 7.83 ENSMUST00000226902.2
ENSMUST00000228353.2
dehydrogenase/reductase (SDR family) member 4
chr17_-_57535003 7.81 ENSMUST00000177046.2
ENSMUST00000024988.15
complement component 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
25.9 103.7 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
17.5 52.5 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
17.4 52.3 GO:0006553 lysine metabolic process(GO:0006553)
14.9 44.6 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
12.7 38.2 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
12.6 37.8 GO:0018931 naphthalene metabolic process(GO:0018931) naphthalene-containing compound metabolic process(GO:0090420)
12.3 49.2 GO:0061402 positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
12.2 49.0 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
9.9 39.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
9.5 28.5 GO:0010133 proline catabolic process to glutamate(GO:0010133)
9.4 37.6 GO:0045329 carnitine biosynthetic process(GO:0045329)
8.4 33.6 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
7.0 21.1 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
6.6 33.2 GO:0006548 histidine catabolic process(GO:0006548)
6.5 19.5 GO:0044240 negative regulation of lipoprotein oxidation(GO:0034443) multicellular organism lipid catabolic process(GO:0044240)
6.3 18.8 GO:0018879 biphenyl metabolic process(GO:0018879)
6.2 142.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
6.1 24.6 GO:0006069 ethanol oxidation(GO:0006069)
6.1 18.4 GO:0006562 proline catabolic process(GO:0006562)
6.0 24.1 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
5.3 48.0 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
4.8 150.0 GO:0019373 epoxygenase P450 pathway(GO:0019373)
4.8 19.3 GO:0010915 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916) positive regulation of phospholipid catabolic process(GO:0060697)
4.8 19.1 GO:0019676 ammonia assimilation cycle(GO:0019676) histone H3-R17 methylation(GO:0034971) bile acid signaling pathway(GO:0038183)
4.8 14.3 GO:0006601 creatine biosynthetic process(GO:0006601)
4.7 28.0 GO:0071267 amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
4.5 40.1 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
4.4 8.8 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
4.3 21.7 GO:0034371 chylomicron remodeling(GO:0034371)
4.3 8.6 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
4.3 8.5 GO:1902031 regulation of NADP metabolic process(GO:1902031)
4.1 16.3 GO:1902896 terminal web assembly(GO:1902896)
4.1 20.3 GO:0042412 taurine biosynthetic process(GO:0042412)
3.9 7.7 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
3.8 15.4 GO:0034760 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760)
3.8 30.5 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
3.8 30.4 GO:0002034 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
3.6 36.4 GO:0042866 pyruvate biosynthetic process(GO:0042866)
3.6 155.4 GO:0019369 arachidonic acid metabolic process(GO:0019369)
3.6 28.7 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
3.6 10.8 GO:0046108 uridine catabolic process(GO:0006218) uridine metabolic process(GO:0046108)
3.6 17.8 GO:0070543 response to linoleic acid(GO:0070543)
3.5 46.0 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
3.5 17.6 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300)
3.3 9.9 GO:2000612 regulation of thyroid-stimulating hormone secretion(GO:2000612)
3.1 3.1 GO:0001951 intestinal D-glucose absorption(GO:0001951)
3.1 12.2 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
3.0 21.3 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
3.0 3.0 GO:1904729 regulation of intestinal lipid absorption(GO:1904729)
3.0 35.6 GO:0061113 pancreas morphogenesis(GO:0061113)
2.9 8.6 GO:0042360 vitamin E metabolic process(GO:0042360)
2.8 70.7 GO:0080184 response to phenylpropanoid(GO:0080184)
2.7 8.2 GO:2000722 negative regulation of beta-amyloid clearance(GO:1900222) regulation of phenotypic switching(GO:1900239) negative regulation of vascular associated smooth muscle cell migration(GO:1904753) regulation of cardiac vascular smooth muscle cell differentiation(GO:2000722) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
2.7 13.4 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
2.7 16.1 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
2.7 18.6 GO:0060332 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) heme transport(GO:0015886) positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
2.6 10.6 GO:0046226 coumarin metabolic process(GO:0009804) coumarin catabolic process(GO:0046226)
2.6 7.8 GO:0048320 axial mesoderm formation(GO:0048320)
2.5 17.5 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
2.5 7.4 GO:0042732 D-xylose metabolic process(GO:0042732)
2.5 29.5 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
2.4 17.0 GO:1904073 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
2.4 30.6 GO:0009133 nucleoside diphosphate biosynthetic process(GO:0009133)
2.3 6.8 GO:0071288 cellular response to mercury ion(GO:0071288)
2.2 15.6 GO:0015862 uridine transport(GO:0015862)
2.2 32.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
2.1 19.3 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
2.1 8.5 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
2.1 8.4 GO:0046351 disaccharide biosynthetic process(GO:0046351)
2.0 6.0 GO:1903699 tarsal gland development(GO:1903699)
2.0 29.9 GO:0015747 urate transport(GO:0015747)
1.9 5.6 GO:0018900 dichloromethane metabolic process(GO:0018900)
1.9 5.6 GO:1903000 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
1.9 9.3 GO:1904970 brush border assembly(GO:1904970)
1.8 5.5 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986) positive regulation of relaxation of muscle(GO:1901079) regulation of relaxation of smooth muscle(GO:1901080) positive regulation of relaxation of smooth muscle(GO:1901082)
1.8 9.1 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
1.8 5.4 GO:0038189 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190)
1.8 27.2 GO:0046415 urate metabolic process(GO:0046415)
1.8 7.2 GO:0006083 acetate metabolic process(GO:0006083)
1.8 9.0 GO:0046618 drug export(GO:0046618)
1.8 10.7 GO:0034627 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
1.8 23.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
1.8 10.6 GO:0009992 cellular water homeostasis(GO:0009992)
1.7 19.2 GO:0015879 carnitine transport(GO:0015879)
1.7 10.4 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
1.7 17.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
1.7 10.2 GO:0015889 cobalamin transport(GO:0015889)
1.7 3.3 GO:0006740 NADPH regeneration(GO:0006740)
1.6 8.1 GO:0060331 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
1.6 12.7 GO:0001887 selenium compound metabolic process(GO:0001887)
1.6 17.3 GO:1903278 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278)
1.6 9.3 GO:1990166 protein localization to site of double-strand break(GO:1990166)
1.5 4.6 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771)
1.5 44.4 GO:0006144 purine nucleobase metabolic process(GO:0006144)
1.5 8.7 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
1.4 5.8 GO:0016999 antibiotic metabolic process(GO:0016999)
1.4 5.7 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
1.4 7.0 GO:1902724 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
1.4 6.8 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
1.3 21.5 GO:0042574 retinal metabolic process(GO:0042574)
1.3 6.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
1.3 6.5 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
1.3 5.2 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
1.3 2.6 GO:1903179 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
1.3 16.7 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
1.3 5.1 GO:0006014 D-ribose metabolic process(GO:0006014)
1.3 6.3 GO:0042737 drug catabolic process(GO:0042737)
1.3 3.8 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
1.2 21.1 GO:0006570 tyrosine metabolic process(GO:0006570)
1.2 8.4 GO:0006741 NADP biosynthetic process(GO:0006741)
1.2 39.4 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
1.2 6.0 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
1.2 7.1 GO:0061760 antifungal innate immune response(GO:0061760)
1.1 8.0 GO:0042256 mature ribosome assembly(GO:0042256)
1.1 4.6 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
1.1 10.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
1.1 4.5 GO:0061386 closure of optic fissure(GO:0061386)
1.1 18.9 GO:0019682 glyceraldehyde-3-phosphate metabolic process(GO:0019682)
1.1 4.4 GO:1902081 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
1.1 2.2 GO:0006714 sesquiterpenoid metabolic process(GO:0006714)
1.1 11.0 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
1.1 4.4 GO:1903976 negative regulation of glial cell migration(GO:1903976)
1.1 4.4 GO:0042335 cuticle development(GO:0042335)
1.1 3.3 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
1.1 14.1 GO:0042572 retinol metabolic process(GO:0042572)
1.1 3.2 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
1.0 4.2 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
1.0 3.1 GO:0021589 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
1.0 6.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
1.0 5.1 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
1.0 3.0 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
1.0 8.9 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
1.0 3.9 GO:0001969 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
1.0 2.9 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
1.0 6.7 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
1.0 2.9 GO:0015793 glycerol transport(GO:0015793)
0.9 9.4 GO:0060406 positive regulation of penile erection(GO:0060406)
0.9 6.5 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.9 2.8 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.9 5.4 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.9 23.5 GO:0030574 collagen catabolic process(GO:0030574)
0.9 6.1 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.8 2.5 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.8 18.1 GO:0034063 stress granule assembly(GO:0034063)
0.8 4.0 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.8 21.6 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.8 11.2 GO:0043589 skin morphogenesis(GO:0043589)
0.8 8.8 GO:0030242 pexophagy(GO:0030242)
0.8 4.7 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.8 3.1 GO:0051182 coenzyme transport(GO:0051182)
0.7 7.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.7 3.7 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.7 2.2 GO:1903093 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.7 2.2 GO:0036275 response to 5-fluorouracil(GO:0036275)
0.7 2.2 GO:0042694 muscle cell fate specification(GO:0042694)
0.7 6.3 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.7 9.8 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.7 6.3 GO:0061042 vascular wound healing(GO:0061042)
0.7 2.1 GO:0060540 lung lobe formation(GO:0060464) diaphragm morphogenesis(GO:0060540)
0.7 2.1 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.7 12.0 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.7 10.6 GO:0015695 organic cation transport(GO:0015695)
0.7 3.3 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.7 11.8 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.7 3.9 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.7 3.9 GO:1990839 response to endothelin(GO:1990839)
0.6 7.6 GO:0006983 ER overload response(GO:0006983)
0.6 15.0 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.6 5.5 GO:0030321 transepithelial chloride transport(GO:0030321)
0.6 3.0 GO:0007468 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.6 2.4 GO:0015851 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.6 6.6 GO:0046485 ether lipid metabolic process(GO:0046485)
0.6 4.2 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.6 3.6 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.6 3.5 GO:0015676 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.6 5.0 GO:0009437 carnitine metabolic process(GO:0009437)
0.6 3.3 GO:0002159 desmosome assembly(GO:0002159)
0.6 1.7 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.6 2.2 GO:0097017 renal protein absorption(GO:0097017)
0.5 4.9 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.5 2.6 GO:0089700 protein kinase D signaling(GO:0089700)
0.5 9.4 GO:0009404 toxin metabolic process(GO:0009404)
0.5 3.5 GO:0019659 glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.5 1.5 GO:1904582 positive regulation of intracellular mRNA localization(GO:1904582)
0.5 3.9 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.5 2.9 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.5 19.4 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.5 1.9 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.5 16.4 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
0.5 2.4 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.5 1.9 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.5 1.4 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.5 1.4 GO:2000041 regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.5 16.7 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.5 3.7 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.5 4.6 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.5 7.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.4 3.1 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.4 4.0 GO:0002934 desmosome organization(GO:0002934)
0.4 1.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.4 2.2 GO:0048539 bone marrow development(GO:0048539)
0.4 1.7 GO:0009305 protein biotinylation(GO:0009305) response to biotin(GO:0070781) histone biotinylation(GO:0071110)
0.4 1.7 GO:0017126 nucleologenesis(GO:0017126)
0.4 1.7 GO:0060290 transdifferentiation(GO:0060290)
0.4 1.3 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.4 1.7 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.4 1.7 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.4 1.2 GO:0046016 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) positive regulation of transcription by glucose(GO:0046016)
0.4 4.1 GO:0060346 bone trabecula formation(GO:0060346)
0.4 9.4 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.4 2.0 GO:0045578 negative regulation of B cell differentiation(GO:0045578) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.4 6.3 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.4 1.6 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.4 1.6 GO:0003017 lymph circulation(GO:0003017)
0.4 1.9 GO:1990928 response to amino acid starvation(GO:1990928)
0.4 12.3 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.4 0.4 GO:0060459 left lung development(GO:0060459) left lung morphogenesis(GO:0060460)
0.4 4.2 GO:1901072 glucosamine-containing compound catabolic process(GO:1901072)
0.4 2.3 GO:0031179 peptide modification(GO:0031179)
0.4 3.0 GO:0006102 isocitrate metabolic process(GO:0006102)
0.4 16.5 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.4 1.5 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.4 1.5 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.4 1.4 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.4 2.8 GO:0061143 alveolar primary septum development(GO:0061143)
0.4 6.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.3 1.7 GO:0006481 C-terminal protein methylation(GO:0006481)
0.3 1.0 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.3 1.0 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.3 2.4 GO:0006450 regulation of translational fidelity(GO:0006450)
0.3 4.1 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.3 2.3 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.3 15.4 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.3 14.0 GO:0042832 defense response to protozoan(GO:0042832)
0.3 1.0 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.3 1.7 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.3 3.6 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.3 3.2 GO:1902741 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.3 1.3 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.3 4.4 GO:0042448 progesterone metabolic process(GO:0042448)
0.3 6.3 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.3 14.8 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.3 1.5 GO:0021898 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.3 33.2 GO:0008203 cholesterol metabolic process(GO:0008203)
0.3 18.1 GO:0050873 brown fat cell differentiation(GO:0050873)
0.3 2.1 GO:0016266 O-glycan processing(GO:0016266)
0.3 7.3 GO:0046688 response to copper ion(GO:0046688)
0.3 5.5 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.3 1.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.3 1.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.3 1.7 GO:0006776 vitamin A metabolic process(GO:0006776)
0.3 0.8 GO:0071374 response to parathyroid hormone(GO:0071107) cellular response to parathyroid hormone stimulus(GO:0071374)
0.3 3.5 GO:0072675 osteoclast fusion(GO:0072675)
0.3 1.9 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.3 1.6 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.3 1.0 GO:1905154 negative regulation of membrane invagination(GO:1905154)
0.3 1.3 GO:0019321 pentose metabolic process(GO:0019321)
0.3 1.0 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.3 7.0 GO:0051205 protein insertion into membrane(GO:0051205)
0.2 1.0 GO:0009946 proximal/distal axis specification(GO:0009946)
0.2 1.5 GO:0050915 sensory perception of sour taste(GO:0050915)
0.2 2.4 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.2 0.5 GO:0003134 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
0.2 4.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 3.4 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.2 3.8 GO:0043248 proteasome assembly(GO:0043248)
0.2 6.6 GO:0006783 heme biosynthetic process(GO:0006783)
0.2 2.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.2 2.6 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.2 0.7 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.2 2.3 GO:0042407 mitochondrial protein processing(GO:0034982) cristae formation(GO:0042407)
0.2 0.9 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.2 0.7 GO:2000299 negative regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000299)
0.2 1.5 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.2 3.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 1.9 GO:0071285 cellular response to lithium ion(GO:0071285)
0.2 1.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 4.2 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.2 6.9 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.2 2.3 GO:0097421 liver regeneration(GO:0097421)
0.2 20.3 GO:0046849 bone remodeling(GO:0046849)
0.2 3.5 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.2 14.0 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.2 1.9 GO:0006265 DNA topological change(GO:0006265)
0.2 5.7 GO:0002021 response to dietary excess(GO:0002021)
0.2 1.8 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.2 0.6 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.2 0.4 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.2 6.0 GO:0060749 mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377)
0.2 0.8 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.2 1.2 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.2 2.9 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.2 0.6 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.2 10.6 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.2 2.5 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.2 1.3 GO:0021564 vagus nerve development(GO:0021564)
0.2 1.3 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.2 5.4 GO:0045116 protein neddylation(GO:0045116)
0.2 9.0 GO:0060711 labyrinthine layer development(GO:0060711)
0.2 2.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.2 0.9 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.2 0.7 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.2 2.7 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.2 1.1 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.2 1.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.2 0.5 GO:0090367 negative regulation of mRNA modification(GO:0090367)
0.2 1.1 GO:0007006 mitochondrial membrane organization(GO:0007006)
0.2 5.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.2 3.8 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.2 4.8 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.2 4.1 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.2 5.2 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.2 7.1 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2 5.4 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.2 0.8 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.2 4.0 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.2 1.6 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 8.3 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.2 1.9 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.2 2.8 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.2 1.5 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.2 0.9 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.2 3.6 GO:0097006 regulation of plasma lipoprotein particle levels(GO:0097006)
0.2 1.5 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 1.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 1.9 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 2.9 GO:0051923 sulfation(GO:0051923)
0.1 2.0 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.4 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
0.1 1.0 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 4.6 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 1.9 GO:0001778 plasma membrane repair(GO:0001778)
0.1 2.0 GO:0022904 respiratory electron transport chain(GO:0022904)
0.1 0.6 GO:0046112 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856) nucleobase biosynthetic process(GO:0046112)
0.1 3.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 3.1 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 3.7 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.1 7.2 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.1 0.7 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.1 0.2 GO:0002358 B cell homeostatic proliferation(GO:0002358)
0.1 0.8 GO:1904219 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.8 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.1 0.4 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 3.6 GO:0034205 beta-amyloid formation(GO:0034205)
0.1 0.4 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 1.0 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 4.4 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.1 1.0 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 3.6 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 1.1 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.1 0.2 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.1 4.0 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.1 1.8 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.1 0.2 GO:0036145 dendritic cell homeostasis(GO:0036145)
0.1 1.2 GO:0010310 regulation of hydrogen peroxide metabolic process(GO:0010310)
0.1 0.5 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 2.3 GO:0060632 regulation of microtubule-based movement(GO:0060632)
0.1 26.1 GO:0006814 sodium ion transport(GO:0006814)
0.1 1.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.4 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.1 0.3 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 0.7 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.1 2.2 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 3.2 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.1 1.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.9 GO:0006857 oligopeptide transport(GO:0006857)
0.1 0.4 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.1 2.1 GO:0035094 response to nicotine(GO:0035094)
0.1 1.4 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.1 1.6 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.1 0.9 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.6 GO:0030578 PML body organization(GO:0030578)
0.1 17.9 GO:0006839 mitochondrial transport(GO:0006839)
0.1 0.4 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.1 0.7 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 1.5 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.1 0.1 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.1 0.8 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.1 2.7 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 3.3 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.1 0.5 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 3.6 GO:0071347 cellular response to interleukin-1(GO:0071347)
0.1 0.5 GO:0035878 nail development(GO:0035878)
0.1 1.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 2.9 GO:0007032 endosome organization(GO:0007032)
0.1 2.8 GO:0035137 hindlimb morphogenesis(GO:0035137)
0.1 0.3 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.1 0.7 GO:0050957 equilibrioception(GO:0050957)
0.1 1.2 GO:0045851 pH reduction(GO:0045851)
0.1 0.9 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 2.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 3.3 GO:0009880 embryonic pattern specification(GO:0009880)
0.1 1.7 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.1 0.3 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.1 1.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 2.2 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.1 2.3 GO:0002323 natural killer cell activation involved in immune response(GO:0002323)
0.1 0.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 1.5 GO:0032528 microvillus organization(GO:0032528)
0.1 1.4 GO:0009395 phospholipid catabolic process(GO:0009395)
0.1 0.9 GO:0050994 regulation of lipid catabolic process(GO:0050994)
0.1 1.6 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 1.3 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.2 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 1.1 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 5.4 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 2.0 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.6 GO:0006739 NADP metabolic process(GO:0006739)
0.0 1.1 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.4 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 2.0 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 2.1 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 1.0 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.2 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 2.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.0 GO:2000224 regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.7 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.9 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.5 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 1.2 GO:0006284 base-excision repair(GO:0006284)
0.0 0.6 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 0.5 GO:0051601 exocyst localization(GO:0051601)
0.0 0.5 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.3 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.3 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.6 GO:0006641 triglyceride metabolic process(GO:0006641)
0.0 0.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.7 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 1.0 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 1.4 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 0.1 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) negative regulation of protein folding(GO:1903333)
0.0 0.7 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.5 GO:0051491 positive regulation of filopodium assembly(GO:0051491)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
16.2 64.7 GO:0017133 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
11.7 128.7 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
10.1 30.2 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
7.5 67.6 GO:0005577 fibrinogen complex(GO:0005577)
5.1 61.8 GO:0042627 chylomicron(GO:0042627)
4.1 20.6 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
4.0 15.8 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
3.0 20.8 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
2.8 31.3 GO:0097433 dense body(GO:0097433)
2.6 20.7 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
2.1 19.0 GO:0005579 membrane attack complex(GO:0005579)
2.1 63.1 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
1.7 5.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
1.7 17.0 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
1.7 24.8 GO:0008385 IkappaB kinase complex(GO:0008385)
1.6 4.7 GO:1902636 kinociliary basal body(GO:1902636)
1.4 20.3 GO:0098533 ATPase dependent transmembrane transport complex(GO:0098533)
1.3 33.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
1.3 3.9 GO:0070435 Shc-EGFR complex(GO:0070435)
1.3 22.8 GO:0070852 cell body fiber(GO:0070852)
1.2 6.9 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.1 6.8 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
1.0 1.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
1.0 66.9 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
1.0 2.9 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.9 4.6 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.9 5.5 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.9 2.7 GO:1990037 Lewy body core(GO:1990037)
0.9 12.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.8 4.2 GO:0035339 SPOTS complex(GO:0035339)
0.8 16.3 GO:0032433 filopodium tip(GO:0032433)
0.8 116.8 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.7 23.0 GO:0031528 microvillus membrane(GO:0031528)
0.7 42.4 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.7 2.2 GO:0097132 cyclin D2-CDK6 complex(GO:0097132)
0.7 3.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.6 31.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.6 3.5 GO:0070826 paraferritin complex(GO:0070826)
0.6 1.7 GO:0005775 vacuolar lumen(GO:0005775)
0.6 2.3 GO:0005745 m-AAA complex(GO:0005745)
0.5 5.5 GO:0030478 actin cap(GO:0030478)
0.5 8.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.5 1.6 GO:0032783 ELL-EAF complex(GO:0032783)
0.5 2.7 GO:0045160 myosin I complex(GO:0045160)
0.5 1.6 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.5 2.6 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.5 263.7 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.5 9.0 GO:0046581 intercellular canaliculus(GO:0046581)
0.5 8.0 GO:0031091 platelet alpha granule(GO:0031091)
0.5 10.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.5 3.3 GO:0072487 MSL complex(GO:0072487)
0.5 2.3 GO:0005914 spot adherens junction(GO:0005914)
0.4 4.0 GO:0045240 dihydrolipoyl dehydrogenase complex(GO:0045240) oxoglutarate dehydrogenase complex(GO:0045252)
0.4 3.0 GO:0070695 FHF complex(GO:0070695)
0.4 19.1 GO:0005719 nuclear euchromatin(GO:0005719)
0.4 1.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.4 70.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.4 73.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.4 2.9 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.3 1.0 GO:0060473 cortical granule(GO:0060473)
0.3 3.8 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.3 3.1 GO:0005796 Golgi lumen(GO:0005796)
0.3 4.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.3 3.6 GO:0070765 gamma-secretase complex(GO:0070765)
0.3 4.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 10.0 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.3 7.2 GO:0000421 autophagosome membrane(GO:0000421)
0.3 1.4 GO:0044194 cytolytic granule(GO:0044194)
0.3 2.4 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.3 50.2 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.3 27.3 GO:0031526 brush border membrane(GO:0031526)
0.2 0.7 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.2 20.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.2 0.7 GO:0044299 C-fiber(GO:0044299)
0.2 26.7 GO:0005903 brush border(GO:0005903)
0.2 8.8 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.2 3.1 GO:0000813 ESCRT I complex(GO:0000813)
0.2 2.2 GO:0044754 autolysosome(GO:0044754)
0.2 2.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2 3.2 GO:0005915 zonula adherens(GO:0005915)
0.2 42.7 GO:0001650 fibrillar center(GO:0001650)
0.2 6.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 9.3 GO:0035861 site of double-strand break(GO:0035861)
0.2 50.3 GO:0072562 blood microparticle(GO:0072562)
0.2 7.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.2 4.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 4.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.2 1.9 GO:0061574 ASAP complex(GO:0061574)
0.2 1.1 GO:0070876 SOSS complex(GO:0070876)
0.2 1.3 GO:0005638 lamin filament(GO:0005638)
0.2 0.9 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.2 3.3 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.2 9.7 GO:0009925 basal plasma membrane(GO:0009925)
0.2 3.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 4.1 GO:0034706 sodium channel complex(GO:0034706)
0.2 12.5 GO:0014704 intercalated disc(GO:0014704)
0.2 0.8 GO:0002142 stereocilia ankle link complex(GO:0002142)
0.1 1.0 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 1.9 GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177) proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.6 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 4.4 GO:1990204 oxidoreductase complex(GO:1990204)
0.1 0.7 GO:0035841 new growing cell tip(GO:0035841)
0.1 3.2 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.8 GO:0005610 laminin-5 complex(GO:0005610)
0.1 3.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 9.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.6 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 3.2 GO:0030120 vesicle coat(GO:0030120)
0.1 10.3 GO:0005811 lipid particle(GO:0005811)
0.1 0.8 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1 1.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.7 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 1.1 GO:0071203 WASH complex(GO:0071203)
0.1 6.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 1.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.5 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 1.8 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.1 2.0 GO:0044292 dendrite terminus(GO:0044292)
0.1 1.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 4.5 GO:0005604 basement membrane(GO:0005604)
0.1 172.3 GO:0005615 extracellular space(GO:0005615)
0.1 8.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 124.1 GO:0005739 mitochondrion(GO:0005739)
0.1 1.2 GO:0005839 proteasome core complex(GO:0005839)
0.1 1.9 GO:0005686 U2 snRNP(GO:0005686)
0.1 0.4 GO:0071797 LUBAC complex(GO:0071797)
0.1 0.2 GO:0034066 RIC1-RGP1 guanyl-nucleotide exchange factor complex(GO:0034066)
0.1 5.0 GO:0016459 myosin complex(GO:0016459)
0.1 1.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 1.2 GO:0005922 connexon complex(GO:0005922)
0.1 1.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 1.9 GO:0002102 podosome(GO:0002102)
0.1 9.7 GO:0005923 bicellular tight junction(GO:0005923)
0.1 3.2 GO:0031941 filamentous actin(GO:0031941)
0.1 0.6 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.1 1.7 GO:0032040 small-subunit processome(GO:0032040)
0.1 0.3 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.5 GO:0060091 kinocilium(GO:0060091)
0.0 0.8 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.6 GO:0042581 specific granule(GO:0042581)
0.0 3.6 GO:0031301 integral component of organelle membrane(GO:0031301)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.6 GO:0043296 apical junction complex(GO:0043296)
0.0 0.3 GO:0098536 deuterosome(GO:0098536)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 1.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 3.5 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 2.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.9 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.1 GO:0036284 tubulobulbar complex(GO:0036284)
0.0 0.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 2.9 GO:0005770 late endosome(GO:0005770)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 5.3 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 9.4 GO:0016604 nuclear body(GO:0016604)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
30.3 121.2 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
18.8 37.6 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
14.8 44.4 GO:0033971 hydroxyisourate hydrolase activity(GO:0033971)
13.2 39.6 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
12.7 38.2 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326)
10.0 30.0 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
8.7 52.3 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
8.4 42.0 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
8.2 24.6 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
8.2 49.0 GO:0032810 sterol response element binding(GO:0032810)
7.8 38.8 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
7.4 29.7 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
7.0 21.1 GO:0004447 iodide peroxidase activity(GO:0004447)
6.9 41.2 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
6.4 242.3 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
6.0 17.9 GO:0045030 UTP-activated nucleotide receptor activity(GO:0045030)
5.7 22.8 GO:0016842 amidine-lyase activity(GO:0016842)
5.4 27.2 GO:0004743 pyruvate kinase activity(GO:0004743)
5.4 16.2 GO:0047936 glucose 1-dehydrogenase [NAD(P)] activity(GO:0047936)
5.1 20.4 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity(GO:0018455)
4.8 19.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
4.7 32.6 GO:0016841 ammonia-lyase activity(GO:0016841)
4.6 46.0 GO:0070095 fructose-6-phosphate binding(GO:0070095)
4.6 18.4 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
4.4 13.3 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
4.4 30.5 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
4.3 21.7 GO:0035478 chylomicron binding(GO:0035478)
4.0 16.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
3.9 15.7 GO:0005118 sevenless binding(GO:0005118)
3.9 11.8 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
3.8 19.1 GO:0038181 bile acid receptor activity(GO:0038181)
3.7 29.8 GO:0008172 S-methyltransferase activity(GO:0008172)
3.7 11.0 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
3.6 17.8 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
3.5 10.6 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
3.5 21.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
3.5 17.3 GO:0070012 oligopeptidase activity(GO:0070012)
3.2 15.9 GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
3.2 9.5 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
3.1 18.6 GO:0015232 heme transporter activity(GO:0015232)
3.1 58.5 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
3.0 35.8 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
3.0 53.7 GO:0008430 selenium binding(GO:0008430)
3.0 8.9 GO:0034012 glycerone kinase activity(GO:0004371) FAD-AMP lyase (cyclizing) activity(GO:0034012) triokinase activity(GO:0050354)
2.9 8.8 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
2.9 20.3 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
2.9 8.6 GO:0004454 ketohexokinase activity(GO:0004454)
2.9 8.6 GO:0008431 vitamin E binding(GO:0008431)
2.8 8.5 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
2.8 48.0 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
2.6 10.6 GO:0004063 aryldialkylphosphatase activity(GO:0004063)
2.6 10.3 GO:0070404 NADH binding(GO:0070404)
2.5 29.5 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
2.4 12.1 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
2.4 7.2 GO:0019807 aspartoacylase activity(GO:0019807)
2.4 9.6 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
2.3 48.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
2.3 9.1 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
2.2 13.4 GO:0070053 thrombospondin receptor activity(GO:0070053)
2.2 44.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
2.2 6.6 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
2.2 6.6 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
2.1 61.6 GO:0008395 steroid hydroxylase activity(GO:0008395)
2.1 6.3 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
2.1 12.3 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
2.0 16.3 GO:0035727 lysophosphatidic acid binding(GO:0035727)
2.0 24.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
1.9 11.5 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
1.9 5.7 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
1.9 5.6 GO:0016824 hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651)
1.8 10.8 GO:0004850 uridine phosphorylase activity(GO:0004850)
1.8 10.7 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
1.7 8.6 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
1.7 6.8 GO:0030156 benzodiazepine receptor binding(GO:0030156)
1.6 6.5 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
1.6 4.7 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
1.5 6.0 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
1.4 5.7 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
1.4 5.6 GO:0008169 C-methyltransferase activity(GO:0008169)
1.4 9.7 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
1.4 31.2 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
1.3 12.1 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
1.3 5.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
1.3 36.1 GO:0001848 complement binding(GO:0001848)
1.3 5.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
1.2 33.6 GO:0005452 inorganic anion exchanger activity(GO:0005452)
1.2 7.3 GO:0008384 IkappaB kinase activity(GO:0008384)
1.2 7.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
1.2 4.8 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
1.2 15.5 GO:0016151 nickel cation binding(GO:0016151)
1.1 4.6 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
1.1 4.6 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
1.1 10.2 GO:0031419 cobalamin binding(GO:0031419)
1.1 27.1 GO:0071949 FAD binding(GO:0071949)
1.1 25.1 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
1.1 6.5 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
1.1 4.3 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
1.1 9.5 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
1.0 2.0 GO:0000253 3-keto sterol reductase activity(GO:0000253)
1.0 1.0 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
1.0 3.0 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
1.0 6.0 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
1.0 17.8 GO:0034185 apolipoprotein binding(GO:0034185)
1.0 11.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
1.0 7.7 GO:0005124 scavenger receptor binding(GO:0005124)
1.0 2.9 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
1.0 20.9 GO:0044548 S100 protein binding(GO:0044548)
0.9 3.8 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.9 8.4 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.9 9.3 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.9 6.5 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.9 37.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.9 6.4 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.8 6.7 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.8 8.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.8 2.4 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.8 4.0 GO:0016726 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.8 20.5 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.8 7.0 GO:0031849 olfactory receptor binding(GO:0031849)
0.8 3.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.7 4.4 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.7 5.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.7 5.8 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.7 5.0 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.7 2.8 GO:0033797 selenate reductase activity(GO:0033797)
0.7 7.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.7 3.4 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.7 6.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.7 8.7 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451)
0.7 3.9 GO:0048408 epidermal growth factor binding(GO:0048408)
0.6 5.2 GO:0016801 hydrolase activity, acting on ether bonds(GO:0016801) ether hydrolase activity(GO:0016803)
0.6 4.5 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.6 5.6 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.6 5.0 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.6 2.5 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.6 8.0 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.6 1.8 GO:0019776 Atg8 ligase activity(GO:0019776)
0.6 1.8 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.6 10.6 GO:0003993 acid phosphatase activity(GO:0003993)
0.6 11.1 GO:0017127 cholesterol transporter activity(GO:0017127)
0.6 6.9 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.6 4.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.6 4.0 GO:0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.6 14.7 GO:0017081 chloride channel regulator activity(GO:0017081)
0.6 16.7 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.6 32.1 GO:0009055 electron carrier activity(GO:0009055)
0.6 2.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.5 2.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.5 4.1 GO:0033592 RNA strand annealing activity(GO:0033592)
0.5 2.0 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.5 21.5 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.5 18.9 GO:0042165 neurotransmitter binding(GO:0042165)
0.5 2.4 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.5 1.4 GO:0050479 glyceryl-ether monooxygenase activity(GO:0050479)
0.5 3.8 GO:0097108 hedgehog family protein binding(GO:0097108)
0.5 20.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.5 1.9 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.5 3.2 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
0.4 1.3 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.4 3.1 GO:0070573 metallodipeptidase activity(GO:0070573)
0.4 4.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.4 6.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.4 2.2 GO:0002046 opsin binding(GO:0002046)
0.4 1.7 GO:0004080 biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271)
0.4 1.6 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.4 7.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.4 5.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.4 1.2 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.4 1.6 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.4 5.5 GO:0004017 adenylate kinase activity(GO:0004017)
0.4 9.7 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.4 2.7 GO:0004977 melanocortin receptor activity(GO:0004977)
0.4 1.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.4 3.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.4 13.5 GO:0004623 phospholipase A2 activity(GO:0004623)
0.4 2.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.4 84.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.4 3.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.4 2.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.4 7.3 GO:0030957 Tat protein binding(GO:0030957)
0.4 26.2 GO:0005507 copper ion binding(GO:0005507)
0.4 4.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.4 7.8 GO:0005003 ephrin receptor activity(GO:0005003)
0.3 1.7 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.3 1.0 GO:0070002 glutamic-type peptidase activity(GO:0070002)
0.3 4.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.3 1.3 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.3 37.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.3 1.0 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.3 3.5 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.3 1.9 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.3 0.9 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.3 18.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.3 0.9 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.3 4.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 4.7 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.3 0.9 GO:0004615 phosphomannomutase activity(GO:0004615)
0.3 14.7 GO:0043531 ADP binding(GO:0043531)
0.3 2.6 GO:0050897 cobalt ion binding(GO:0050897)
0.3 0.9 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846) diacylglycerol O-acyltransferase activity(GO:0004144)
0.3 1.4 GO:0004974 leukotriene receptor activity(GO:0004974)
0.3 3.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.3 3.0 GO:0010181 FMN binding(GO:0010181)
0.3 4.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.3 15.4 GO:0016836 hydro-lyase activity(GO:0016836)
0.3 1.3 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.3 0.8 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.3 5.2 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.3 3.1 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.3 1.8 GO:0016936 galactoside binding(GO:0016936)
0.2 2.9 GO:0071813 lipoprotein particle binding(GO:0071813) protein-lipid complex binding(GO:0071814)
0.2 1.0 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.2 2.1 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.2 3.9 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.2 0.9 GO:0009374 biotin binding(GO:0009374)
0.2 1.8 GO:0017040 ceramidase activity(GO:0017040)
0.2 0.2 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 34.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 1.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.2 2.1 GO:0051525 NFAT protein binding(GO:0051525)
0.2 5.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.2 0.6 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.2 8.1 GO:0070412 R-SMAD binding(GO:0070412)
0.2 2.4 GO:0097322 7SK snRNA binding(GO:0097322)
0.2 13.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 3.8 GO:0035497 cAMP response element binding(GO:0035497)
0.2 5.1 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.2 4.4 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.2 0.6 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.2 2.3 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.2 10.0 GO:0051213 dioxygenase activity(GO:0051213)
0.2 5.8 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.2 0.7 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.2 1.7 GO:0015288 porin activity(GO:0015288)
0.2 2.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 1.5 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.2 19.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 2.0 GO:0019966 interleukin-1 binding(GO:0019966)
0.2 1.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 1.2 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.2 0.9 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.2 5.0 GO:0020037 heme binding(GO:0020037)
0.1 0.6 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.4 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 6.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 16.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 2.8 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 4.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 3.1 GO:0051787 misfolded protein binding(GO:0051787)
0.1 3.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 17.8 GO:0005506 iron ion binding(GO:0005506)
0.1 2.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.8 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.4 GO:0038100 nodal binding(GO:0038100)
0.1 6.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 1.5 GO:0048038 quinone binding(GO:0048038)
0.1 1.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.5 GO:0019809 spermidine binding(GO:0019809)
0.1 2.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 3.7 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 1.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 3.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 2.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 1.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 1.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 2.9 GO:0004697 protein kinase C activity(GO:0004697)
0.1 10.7 GO:0051087 chaperone binding(GO:0051087)
0.1 3.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.5 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 2.5 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 3.8 GO:0016504 peptidase activator activity(GO:0016504)
0.1 0.6 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.4 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 11.9 GO:0005550 pheromone binding(GO:0005550)
0.1 1.6 GO:0048185 activin binding(GO:0048185)
0.1 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.6 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 7.9 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1 3.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.9 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 1.0 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.1 11.0 GO:0015293 symporter activity(GO:0015293)
0.1 0.5 GO:0097643 amylin receptor activity(GO:0097643)
0.1 4.9 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.1 0.8 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 10.8 GO:0030674 protein binding, bridging(GO:0030674)
0.1 1.8 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.1 1.1 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.1 1.8 GO:0042923 neuropeptide binding(GO:0042923)
0.1 1.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 3.8 GO:0019213 deacetylase activity(GO:0019213)
0.1 3.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 2.4 GO:0005272 sodium channel activity(GO:0005272)
0.1 2.5 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 1.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.6 GO:0043426 MRF binding(GO:0043426)
0.1 1.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 1.7 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 0.2 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.8 GO:0000339 RNA cap binding(GO:0000339)
0.1 2.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 12.4 GO:0008168 methyltransferase activity(GO:0008168)
0.1 1.9 GO:0000049 tRNA binding(GO:0000049)
0.1 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 2.6 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 1.5 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.5 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.3 GO:0019770 IgG receptor activity(GO:0019770)
0.0 1.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.6 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 14.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.6 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 1.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 10.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.9 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.9 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.7 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.6 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 183.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
1.2 67.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.6 29.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.5 19.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.5 4.7 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.5 6.9 ST STAT3 PATHWAY STAT3 Pathway
0.5 15.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.4 11.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.4 17.0 PID IGF1 PATHWAY IGF1 pathway
0.4 11.7 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.4 104.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.3 4.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.3 5.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.3 5.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.2 4.6 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.2 17.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.2 13.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 14.3 PID LKB1 PATHWAY LKB1 signaling events
0.2 5.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.2 25.6 PID CMYB PATHWAY C-MYB transcription factor network
0.2 5.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.2 4.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2 8.8 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.2 1.9 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 8.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 3.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 2.9 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 8.3 PID FGF PATHWAY FGF signaling pathway
0.1 2.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 2.0 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 1.6 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 1.3 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 1.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 3.2 PID REELIN PATHWAY Reelin signaling pathway
0.1 1.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 7.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 0.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 2.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 0.8 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 1.7 PID ARF6 PATHWAY Arf6 signaling events
0.1 1.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 1.4 PID ENDOTHELIN PATHWAY Endothelins
0.1 2.9 PID P73PATHWAY p73 transcription factor network
0.1 1.6 PID ALK1 PATHWAY ALK1 signaling events
0.1 1.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 2.0 PID FOXO PATHWAY FoxO family signaling
0.0 2.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 2.0 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.6 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.7 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.8 PID PDGFRB PATHWAY PDGFR-beta signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
6.5 188.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
6.1 103.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
5.3 15.8 REACTOME XENOBIOTICS Genes involved in Xenobiotics
5.2 89.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
4.6 74.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
3.4 79.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
2.5 32.7 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
2.5 39.6 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
2.2 24.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
1.8 20.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
1.8 16.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
1.7 57.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
1.4 12.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
1.4 23.0 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
1.3 18.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
1.3 64.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
1.0 21.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
1.0 32.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
1.0 16.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
1.0 73.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.9 19.4 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.9 22.0 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.9 19.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.9 72.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.8 15.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.8 84.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.8 164.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.7 22.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.7 9.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.6 32.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.6 13.8 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.6 10.8 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.5 9.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.5 9.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.5 5.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.5 4.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.5 17.8 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.5 8.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.5 29.3 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.5 18.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.4 3.5 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.4 14.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.4 22.5 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.4 6.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.4 1.6 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.4 8.1 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.4 4.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.4 10.6 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.4 3.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.4 24.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.4 14.5 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.3 4.9 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.3 1.3 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.3 4.9 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.3 6.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.3 8.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.3 3.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.3 3.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.3 4.1 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.3 9.2 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.3 3.0 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 3.7 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2 5.9 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.2 0.7 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.2 3.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2 2.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 4.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2 1.8 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 2.9 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 14.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 4.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 5.7 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 14.9 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 5.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 5.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.5 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 1.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.5 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.1 1.6 REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.1 1.0 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 2.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 2.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 2.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.9 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.1 1.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 2.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 3.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 2.6 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 1.2 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.1 0.5 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.1 2.0 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 1.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.0 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.4 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 1.7 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 1.2 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 2.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.9 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.5 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.4 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.2 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.8 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.6 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides