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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Prdm14

Z-value: 0.66

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Transcription factors associated with Prdm14

Gene Symbol Gene ID Gene Info
Prdm14
ENSMUSG00000042414.8 Prdm14

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Prdm14mm39_v1_chr1_-_13197387_131974730.047.6e-01Click!

Activity profile of Prdm14 motif

Sorted Z-values of Prdm14 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Prdm14

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_+_88062508 7.88 ENSMUST00000113134.8
ENSMUST00000140092.8
Ugt1a6a
UDP glucuronosyltransferase 1 family, polypeptide A6A
chr1_+_88030951 7.63 ENSMUST00000113135.6
ENSMUST00000113138.8
Ugt1a7c
Ugt1a6b
UDP glucuronosyltransferase 1 family, polypeptide A7C
UDP glucuronosyltransferase 1 family, polypeptide A6B
chr11_+_96173475 6.11 ENSMUST00000168043.2
Hoxb8
homeobox B8
chr11_+_96173355 5.17 ENSMUST00000125410.2
Hoxb8
homeobox B8
chr17_-_35081129 5.08 ENSMUST00000154526.8
Cfb
complement factor B
chr17_-_35081456 4.65 ENSMUST00000025229.11
ENSMUST00000176203.9
ENSMUST00000128767.8
Cfb
complement factor B
chr4_+_133280680 4.16 ENSMUST00000042706.3
Nr0b2
nuclear receptor subfamily 0, group B, member 2
chr6_+_72332449 4.14 ENSMUST00000206064.2
Tmem150a
transmembrane protein 150A
chr2_-_143853122 3.79 ENSMUST00000016072.12
ENSMUST00000037875.6
Rrbp1
ribosome binding protein 1
chr6_+_72332423 3.74 ENSMUST00000069695.9
ENSMUST00000132243.3
Tmem150a
transmembrane protein 150A
chr6_+_91661034 3.60 ENSMUST00000032185.9
Slc6a6
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr6_+_72333209 3.31 ENSMUST00000206531.2
Tmem150a
transmembrane protein 150A
chr6_+_91661074 3.12 ENSMUST00000205480.2
ENSMUST00000206545.2
Slc6a6
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr13_+_74787952 2.45 ENSMUST00000221822.2
ENSMUST00000221526.2
Erap1
endoplasmic reticulum aminopeptidase 1
chr9_+_102595628 2.45 ENSMUST00000156485.2
ENSMUST00000145937.2
ENSMUST00000134483.2
ENSMUST00000190047.7
Amotl2
angiomotin-like 2
chr8_+_46945826 2.22 ENSMUST00000110371.8
Acsl1
acyl-CoA synthetase long-chain family member 1
chr1_-_173703424 2.11 ENSMUST00000186442.7
Mndal
myeloid nuclear differentiation antigen like
chr14_-_72947422 2.10 ENSMUST00000089017.12
Fndc3a
fibronectin type III domain containing 3A
chr11_+_43046476 2.06 ENSMUST00000238415.2
Atp10b
ATPase, class V, type 10B
chr13_-_95661726 2.03 ENSMUST00000022185.10
F2rl1
coagulation factor II (thrombin) receptor-like 1
chrX_+_73314418 1.99 ENSMUST00000008826.14
ENSMUST00000151702.8
ENSMUST00000074085.12
ENSMUST00000135690.2
Rpl10
ribosomal protein L10
chr19_-_6117815 1.81 ENSMUST00000162575.8
ENSMUST00000159084.8
ENSMUST00000161718.8
ENSMUST00000162810.8
ENSMUST00000025713.12
ENSMUST00000113543.9
ENSMUST00000160417.8
ENSMUST00000161528.2
Tm7sf2
transmembrane 7 superfamily member 2
chr4_+_155646807 1.76 ENSMUST00000030939.14
Nadk
NAD kinase
chr16_+_43056218 1.70 ENSMUST00000146708.8
Zbtb20
zinc finger and BTB domain containing 20
chr9_+_65102635 1.66 ENSMUST00000216702.2
Parp16
poly (ADP-ribose) polymerase family, member 16
chr15_+_99499252 1.60 ENSMUST00000230075.2
ENSMUST00000023754.6
Aqp6
aquaporin 6
chrX_+_13147209 1.56 ENSMUST00000000804.7
Ddx3x
DEAD box helicase 3, X-linked
chr11_+_3599183 1.41 ENSMUST00000096441.5
Morc2a
microrchidia 2A
chr10_+_43455919 1.26 ENSMUST00000214476.2
Cd24a
CD24a antigen
chr11_+_23234644 1.22 ENSMUST00000150750.3
Xpo1
exportin 1
chr15_+_44291470 1.16 ENSMUST00000226827.2
ENSMUST00000060652.5
Eny2
ENY2 transcription and export complex 2 subunit
chr2_-_45003270 1.12 ENSMUST00000202935.4
ENSMUST00000068415.11
ENSMUST00000127520.8
Zeb2
zinc finger E-box binding homeobox 2
chr6_+_87405968 1.09 ENSMUST00000032125.7
Bmp10
bone morphogenetic protein 10
chr15_-_73579236 1.05 ENSMUST00000064166.5
Gpr20
G protein-coupled receptor 20
chr17_+_44445659 1.01 ENSMUST00000239215.2
Clic5
chloride intracellular channel 5
chr17_+_33774681 1.01 ENSMUST00000087605.13
ENSMUST00000174695.2
Myo1f
myosin IF
chr15_+_102368510 1.01 ENSMUST00000164688.2
Prr13
proline rich 13
chr19_+_8861096 0.93 ENSMUST00000187504.7
Lbhd1
LBH domain containing 1
chr7_-_143014726 0.88 ENSMUST00000167912.9
ENSMUST00000037287.8
Cdkn1c
cyclin-dependent kinase inhibitor 1C (P57)
chr6_+_54016543 0.83 ENSMUST00000046856.14
Chn2
chimerin 2
chr6_-_108162513 0.83 ENSMUST00000167338.8
ENSMUST00000172188.2
ENSMUST00000032191.16
Sumf1
sulfatase modifying factor 1
chr15_-_44291699 0.79 ENSMUST00000038719.8
Nudcd1
NudC domain containing 1
chr6_+_28475099 0.72 ENSMUST00000168362.2
Snd1
staphylococcal nuclease and tudor domain containing 1
chr7_+_114344920 0.70 ENSMUST00000136645.8
ENSMUST00000169913.8
Insc
INSC spindle orientation adaptor protein
chr3_-_90120942 0.64 ENSMUST00000195998.5
ENSMUST00000197361.5
ENSMUST00000170122.4
Rps27
ribosomal protein S27
chr15_-_76191301 0.64 ENSMUST00000171340.9
ENSMUST00000023222.13
ENSMUST00000164189.2
Oplah
5-oxoprolinase (ATP-hydrolysing)
chr9_-_14815163 0.58 ENSMUST00000069408.10
Izumo1r
IZUMO1 receptor, JUNO
chr9_-_14815050 0.57 ENSMUST00000148155.2
ENSMUST00000121116.8
Izumo1r
IZUMO1 receptor, JUNO
chr10_-_128579879 0.57 ENSMUST00000026414.9
Dgka
diacylglycerol kinase, alpha
chr12_-_113271532 0.56 ENSMUST00000192188.3
ENSMUST00000103418.3
Ighg2b
immunoglobulin heavy constant gamma 2B
chr9_-_14815228 0.53 ENSMUST00000034409.14
ENSMUST00000117620.8
Izumo1r
IZUMO1 receptor, JUNO
chr4_+_116983995 0.51 ENSMUST00000062206.3
Dynlt4
dynein light chain Tctex-type 4
chr6_-_42437951 0.46 ENSMUST00000090156.2
Olfr458
olfactory receptor 458
chr4_+_116983973 0.44 ENSMUST00000134074.8
Dynlt4
dynein light chain Tctex-type 4
chr19_+_8861274 0.42 ENSMUST00000177826.2
Gm49403
predicted gene, 49403
chr4_-_88357112 0.39 ENSMUST00000132493.8
ENSMUST00000030221.3
ENSMUST00000151280.8
Hacd4
3-hydroxyacyl-CoA dehydratase 4
chr6_+_83086021 0.38 ENSMUST00000113938.5
Mrpl53
mitochondrial ribosomal protein L53
chr1_+_191709329 0.37 ENSMUST00000180463.3
ENSMUST00000181512.8
Rd3
retinal degeneration 3
chr8_+_10299288 0.31 ENSMUST00000214643.2
Myo16
myosin XVI
chr13_-_120412342 0.31 ENSMUST00000180768.2
B020031M17Rik
RIKEN cDNA B020031M17 gene
chr5_+_98402182 0.08 ENSMUST00000200059.2
Fgf5
fibroblast growth factor 5
chr4_+_126915104 0.07 ENSMUST00000030623.8
Sfpq
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
chr3_-_63758672 0.06 ENSMUST00000162269.9
ENSMUST00000159676.9
ENSMUST00000175947.8
Plch1
phospholipase C, eta 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.6 GO:0006711 estrogen catabolic process(GO:0006711)
2.2 6.7 GO:0015734 beta-alanine transport(GO:0001762) taurine transport(GO:0015734)
0.8 7.9 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.7 2.0 GO:1900135 positive regulation of eosinophil degranulation(GO:0043311) regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949) positive regulation of renin secretion into blood stream(GO:1900135) positive regulation of eosinophil activation(GO:1902568)
0.6 9.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.4 1.3 GO:0034117 erythrocyte aggregation(GO:0034117) regulation of erythrocyte aggregation(GO:0034118)
0.4 11.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.3 11.2 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.3 1.7 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.2 1.6 GO:0042256 mature ribosome assembly(GO:0042256)
0.2 1.8 GO:0006741 NADP biosynthetic process(GO:0006741)
0.2 2.0 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.2 2.4 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 2.2 GO:0044539 long-chain fatty acid import(GO:0044539)
0.1 1.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 1.1 GO:0010612 regulation of cardiac muscle adaptation(GO:0010612) positive regulation of sarcomere organization(GO:0060298) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.1 0.6 GO:0001798 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) positive regulation of type IIa hypersensitivity(GO:0001798) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892) positive regulation of type II hypersensitivity(GO:0002894)
0.1 1.7 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 1.6 GO:0006833 water transport(GO:0006833)
0.1 2.1 GO:0060009 Sertoli cell development(GO:0060009)
0.1 1.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 2.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 2.4 GO:0035329 hippo signaling(GO:0035329)
0.1 1.0 GO:0002024 diet induced thermogenesis(GO:0002024)
0.1 1.0 GO:0043312 neutrophil degranulation(GO:0043312)
0.0 0.6 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 4.2 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 1.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 1.0 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 1.8 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.0 0.4 GO:0030497 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.7 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 GO:0031143 pseudopodium(GO:0031143)
0.1 1.2 GO:0005642 annulate lamellae(GO:0005642)
0.1 1.6 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 1.2 GO:0000124 SAGA complex(GO:0000124)
0.1 0.7 GO:0097433 dense body(GO:0097433)
0.0 1.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 2.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.0 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 10.3 GO:0072562 blood microparticle(GO:0072562)
0.0 6.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 2.2 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 11.2 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 7.3 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.3 GO:0016459 myosin complex(GO:0016459)
0.0 2.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 2.4 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.7 GO:0005369 beta-alanine transmembrane transporter activity(GO:0001761) taurine transmembrane transporter activity(GO:0005368) taurine:sodium symporter activity(GO:0005369)
0.5 2.0 GO:0015057 thrombin receptor activity(GO:0015057)
0.4 2.2 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.4 15.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 2.4 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.2 1.6 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 4.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 1.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 1.1 GO:0031433 telethonin binding(GO:0031433)
0.1 1.6 GO:0015250 water channel activity(GO:0015250)
0.1 2.3 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 0.4 GO:0102345 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.1 0.6 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 2.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 1.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 1.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 1.8 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 1.7 GO:0005542 folic acid binding(GO:0005542)
0.0 0.9 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 9.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 3.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 2.6 GO:0003735 structural constituent of ribosome(GO:0003735)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 4.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 1.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.8 ST GA12 PATHWAY G alpha 12 Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 9.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.3 6.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 2.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 0.8 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 2.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 2.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 2.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 3.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 2.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors