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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Prdm4

Z-value: 0.56

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Transcription factors associated with Prdm4

Gene Symbol Gene ID Gene Info
Prdm4
ENSMUSG00000035529.11 Prdm4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Prdm4mm39_v1_chr10_-_85752765_857528700.085.2e-01Click!

Activity profile of Prdm4 motif

Sorted Z-values of Prdm4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Prdm4

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr12_+_113115632 7.50 ENSMUST00000006523.12
ENSMUST00000200553.2
Crip1
cysteine-rich protein 1 (intestinal)
chrX_+_21581135 6.62 ENSMUST00000033414.8
Slc6a14
solute carrier family 6 (neurotransmitter transporter), member 14
chr8_+_123920682 5.71 ENSMUST00000212409.2
Dpep1
dipeptidase 1
chr18_+_42186713 4.49 ENSMUST00000072008.11
Sh3rf2
SH3 domain containing ring finger 2
chr18_+_42186757 4.35 ENSMUST00000074679.4
Sh3rf2
SH3 domain containing ring finger 2
chr11_+_102495189 4.32 ENSMUST00000057893.7
Fzd2
frizzled class receptor 2
chr10_+_26698556 4.15 ENSMUST00000135866.2
Arhgap18
Rho GTPase activating protein 18
chr10_+_126814542 3.77 ENSMUST00000105256.10
Ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr5_-_142803135 3.22 ENSMUST00000198181.2
Tnrc18
trinucleotide repeat containing 18
chr5_-_4808026 2.50 ENSMUST00000054294.7
Fzd1
frizzled class receptor 1
chr1_+_74430575 2.16 ENSMUST00000027367.14
Ctdsp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr5_-_142803405 2.03 ENSMUST00000151477.8
Tnrc18
trinucleotide repeat containing 18
chr5_-_144902598 1.43 ENSMUST00000110677.8
ENSMUST00000085684.11
ENSMUST00000100461.7
Smurf1
SMAD specific E3 ubiquitin protein ligase 1
chr12_-_111947487 1.04 ENSMUST00000190536.2
Rd3l
retinal degeneration 3-like
chr12_-_111947536 0.72 ENSMUST00000185354.2
Rd3l
retinal degeneration 3-like
chr12_-_111946560 0.38 ENSMUST00000190680.2
Rd3l
retinal degeneration 3-like
chr13_-_23735822 0.38 ENSMUST00000102971.2
H4c6
H4 clustered histone 6
chr15_-_99372575 0.25 ENSMUST00000040313.6
Bcdin3d
BCDIN3 domain containing
chr12_+_51424343 0.24 ENSMUST00000219434.2
ENSMUST00000021335.7
Scfd1
Sec1 family domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.7 GO:0016999 antibiotic metabolic process(GO:0016999)
1.0 6.8 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.5 1.4 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.5 7.5 GO:0071493 cellular response to UV-B(GO:0071493)
0.3 5.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 5.9 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.1 8.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 6.6 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 4.1 GO:0030833 regulation of actin filament polymerization(GO:0030833)
0.0 0.2 GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 6.6 GO:0031526 brush border membrane(GO:0031526)
0.0 5.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.6 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.8 5.7 GO:0070573 metallodipeptidase activity(GO:0070573)
0.6 5.9 GO:0008420 CTD phosphatase activity(GO:0008420)
0.4 7.5 GO:0008301 DNA binding, bending(GO:0008301)
0.3 6.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 8.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 1.4 GO:0070411 I-SMAD binding(GO:0070411)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 5.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.4 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 3.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 1.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 6.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 4.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases