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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Prox1

Z-value: 0.81

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Transcription factors associated with Prox1

Gene Symbol Gene ID Gene Info
Prox1
ENSMUSG00000010175.14 Prox1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Prox1mm39_v1_chr1_-_189901596_189901723-0.161.7e-01Click!

Activity profile of Prox1 motif

Sorted Z-values of Prox1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Prox1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr16_+_22965286 5.69 ENSMUST00000023593.6
Adipoq
adiponectin, C1Q and collagen domain containing
chr16_+_22965330 5.04 ENSMUST00000171309.2
Adipoq
adiponectin, C1Q and collagen domain containing
chr19_-_15901919 4.38 ENSMUST00000162053.8
Psat1
phosphoserine aminotransferase 1
chr10_-_80649315 4.19 ENSMUST00000181039.8
ENSMUST00000180438.2
Jsrp1
junctional sarcoplasmic reticulum protein 1
chr7_+_141995545 4.07 ENSMUST00000105971.8
ENSMUST00000145287.8
Tnni2
troponin I, skeletal, fast 2
chr18_-_68562385 3.90 ENSMUST00000052347.8
Mc2r
melanocortin 2 receptor
chr14_-_56181993 3.89 ENSMUST00000022834.7
ENSMUST00000226280.2
Cma1
chymase 1, mast cell
chr4_-_137157824 3.83 ENSMUST00000102522.5
Cela3b
chymotrypsin-like elastase family, member 3B
chr17_+_29538157 3.70 ENSMUST00000114699.9
ENSMUST00000155348.3
ENSMUST00000234618.2
Pi16
peptidase inhibitor 16
chr14_-_51384236 3.56 ENSMUST00000080126.4
Rnase1
ribonuclease, RNase A family, 1 (pancreatic)
chr15_+_102898966 3.47 ENSMUST00000001703.8
Hoxc8
homeobox C8
chr11_+_4936824 2.59 ENSMUST00000109897.8
ENSMUST00000009234.16
Ap1b1
adaptor protein complex AP-1, beta 1 subunit
chr4_+_42950367 2.42 ENSMUST00000084662.12
Dnajb5
DnaJ heat shock protein family (Hsp40) member B5
chr1_-_169575203 2.24 ENSMUST00000027991.12
ENSMUST00000111357.2
Rgs4
regulator of G-protein signaling 4
chr8_+_31601837 2.11 ENSMUST00000046941.8
ENSMUST00000217278.2
Rnf122
ring finger protein 122
chr5_+_24305577 1.91 ENSMUST00000030841.10
ENSMUST00000163409.5
Klhl7
kelch-like 7
chr15_-_86070338 1.90 ENSMUST00000044332.16
Cerk
ceramide kinase
chrY_-_90850446 1.83 ENSMUST00000179623.2
Gm21748
predicted gene, 21748
chr4_+_130640436 1.80 ENSMUST00000151698.8
Laptm5
lysosomal-associated protein transmembrane 5
chr8_-_70929555 1.79 ENSMUST00000066597.13
ENSMUST00000210250.2
ENSMUST00000209415.2
ENSMUST00000166976.3
Klhl26
kelch-like 26
chr4_+_130640611 1.77 ENSMUST00000156225.8
ENSMUST00000156742.8
Laptm5
lysosomal-associated protein transmembrane 5
chr17_+_37356854 1.76 ENSMUST00000025338.16
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr18_-_67378886 1.61 ENSMUST00000073054.5
Mppe1
metallophosphoesterase 1
chr6_+_146697539 1.58 ENSMUST00000111639.8
Arntl2
aryl hydrocarbon receptor nuclear translocator-like 2
chr8_+_89015705 1.44 ENSMUST00000171456.9
Adcy7
adenylate cyclase 7
chr6_-_131365380 1.44 ENSMUST00000032309.13
ENSMUST00000087865.4
Ybx3
Y box protein 3
chr4_-_133694607 1.40 ENSMUST00000105893.8
Hmgn2
high mobility group nucleosomal binding domain 2
chr18_+_37864045 1.32 ENSMUST00000192535.2
Pcdhgb5
protocadherin gamma subfamily B, 5
chr5_+_139238069 1.31 ENSMUST00000026976.12
Get4
golgi to ER traffic protein 4
chr5_+_139197689 1.30 ENSMUST00000148772.8
ENSMUST00000110882.8
Sun1
Sad1 and UNC84 domain containing 1
chr17_+_37356872 1.27 ENSMUST00000174456.8
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr8_+_61085890 1.27 ENSMUST00000160719.8
Mfap3l
microfibrillar-associated protein 3-like
chr4_+_74160705 1.25 ENSMUST00000077851.10
Kdm4c
lysine (K)-specific demethylase 4C
chr1_+_78794475 1.20 ENSMUST00000057262.8
ENSMUST00000187432.2
Kcne4
potassium voltage-gated channel, Isk-related subfamily, gene 4
chr18_-_67378512 1.17 ENSMUST00000237631.2
Mppe1
metallophosphoesterase 1
chr4_-_137137088 1.14 ENSMUST00000024200.7
Cela3a
chymotrypsin-like elastase family, member 3A
chr17_+_28059129 1.13 ENSMUST00000233657.2
Snrpc
U1 small nuclear ribonucleoprotein C
chr4_-_133694543 1.10 ENSMUST00000123234.8
Hmgn2
high mobility group nucleosomal binding domain 2
chr5_-_124492734 1.08 ENSMUST00000031341.11
Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr17_-_35827676 1.06 ENSMUST00000160885.2
ENSMUST00000159009.2
ENSMUST00000161012.8
Tcf19
transcription factor 19
chr17_-_33613544 1.02 ENSMUST00000174512.4
ENSMUST00000167107.10
Zfp101
zinc finger protein 101
chr2_+_36120438 1.02 ENSMUST00000062069.6
Ptgs1
prostaglandin-endoperoxide synthase 1
chr5_+_139238089 1.01 ENSMUST00000130326.8
Get4
golgi to ER traffic protein 4
chr7_-_48106079 0.98 ENSMUST00000094384.4
Mrgprb1
MAS-related GPR, member B1
chr17_+_28059099 0.95 ENSMUST00000233752.2
Snrpc
U1 small nuclear ribonucleoprotein C
chr2_+_26899935 0.90 ENSMUST00000114005.9
ENSMUST00000114004.8
ENSMUST00000114006.8
ENSMUST00000114007.8
ENSMUST00000133807.2
Cacfd1
calcium channel flower domain containing 1
chr17_-_35191127 0.85 ENSMUST00000087328.4
Hspa1a
heat shock protein 1A
chr4_+_59003121 0.84 ENSMUST00000095070.4
ENSMUST00000174664.2
Dnajc25
Gm20503
DnaJ heat shock protein family (Hsp40) member C25
predicted gene 20503
chr19_-_8691797 0.81 ENSMUST00000206797.2
Slc3a2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr11_-_72098239 0.80 ENSMUST00000238653.2
ENSMUST00000108505.2
4933427D14Rik
RIKEN cDNA 4933427D14 gene
chr11_-_8614497 0.75 ENSMUST00000020695.13
Tns3
tensin 3
chr17_-_37574640 0.73 ENSMUST00000080759.5
Olfr98
olfactory receptor 98
chr12_-_83534482 0.72 ENSMUST00000177959.8
ENSMUST00000178756.8
Dpf3
D4, zinc and double PHD fingers, family 3
chr18_+_46983105 0.71 ENSMUST00000025358.4
ENSMUST00000234519.2
Lvrn
laeverin
chr4_-_63779562 0.67 ENSMUST00000030047.3
Tnfsf8
tumor necrosis factor (ligand) superfamily, member 8
chr18_+_10617773 0.67 ENSMUST00000002551.5
ENSMUST00000234207.2
Snrpd1
small nuclear ribonucleoprotein D1
chr8_+_61085853 0.66 ENSMUST00000161421.2
Mfap3l
microfibrillar-associated protein 3-like
chr5_-_86780277 0.64 ENSMUST00000116553.9
Tmprss11f
transmembrane protease, serine 11f
chr11_-_115824290 0.63 ENSMUST00000021097.10
Recql5
RecQ protein-like 5
chr6_+_60921456 0.62 ENSMUST00000129603.4
ENSMUST00000204333.2
Mmrn1
multimerin 1
chr9_+_109760931 0.62 ENSMUST00000165876.8
Map4
microtubule-associated protein 4
chr12_-_40273173 0.62 ENSMUST00000001672.12
Ifrd1
interferon-related developmental regulator 1
chr11_+_19874354 0.60 ENSMUST00000093299.13
Spred2
sprouty-related EVH1 domain containing 2
chr6_-_106725895 0.59 ENSMUST00000205004.2
Il5ra
interleukin 5 receptor, alpha
chr19_+_46044972 0.58 ENSMUST00000111899.8
ENSMUST00000099392.10
ENSMUST00000062322.11
Pprc1
peroxisome proliferative activated receptor, gamma, coactivator-related 1
chr19_-_8691220 0.58 ENSMUST00000010239.6
Slc3a2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr3_+_89738654 0.56 ENSMUST00000050401.6
She
src homology 2 domain-containing transforming protein E
chr17_+_28059036 0.55 ENSMUST00000071006.9
Snrpc
U1 small nuclear ribonucleoprotein C
chr7_-_48106037 0.54 ENSMUST00000188095.2
Mrgprb1
MAS-related GPR, member B1
chr3_+_20111958 0.53 ENSMUST00000002502.12
Hltf
helicase-like transcription factor
chr17_-_83821716 0.52 ENSMUST00000025095.9
ENSMUST00000167741.9
Cox7a2l
cytochrome c oxidase subunit 7A2 like
chr9_+_109760856 0.49 ENSMUST00000169851.8
Map4
microtubule-associated protein 4
chr7_+_28416194 0.49 ENSMUST00000032818.13
Fbxo17
F-box protein 17
chr19_+_46140942 0.48 ENSMUST00000026254.14
Gbf1
golgi-specific brefeldin A-resistance factor 1
chr6_-_106725929 0.48 ENSMUST00000204659.3
Il5ra
interleukin 5 receptor, alpha
chrX_-_73009933 0.47 ENSMUST00000114372.3
ENSMUST00000033761.13
Hcfc1
host cell factor C1
chr3_+_92980844 0.44 ENSMUST00000195847.2
ENSMUST00000179064.2
Tdpoz8
TD and POZ domain containing 8
chr8_+_85807369 0.43 ENSMUST00000079764.14
Wdr83os
WD repeat domain 83 opposite strand
chr7_+_23781311 0.43 ENSMUST00000207002.2
ENSMUST00000068975.6
ENSMUST00000203854.3
Zfp180
zinc finger protein 180
chr17_+_37716368 0.43 ENSMUST00000077008.4
Olfr107
olfactory receptor 107
chr12_+_111409087 0.42 ENSMUST00000109792.8
Tnfaip2
tumor necrosis factor, alpha-induced protein 2
chr7_+_28416270 0.39 ENSMUST00000108279.9
Fbxo17
F-box protein 17
chr6_+_29361408 0.38 ENSMUST00000156163.2
Calu
calumenin
chr11_+_115671523 0.37 ENSMUST00000239299.2
Tmem94
transmembrane protein 94
chr10_-_80861239 0.35 ENSMUST00000055125.5
Diras1
DIRAS family, GTP-binding RAS-like 1
chr11_+_19874403 0.33 ENSMUST00000093298.12
Spred2
sprouty-related EVH1 domain containing 2
chr8_-_100143029 0.31 ENSMUST00000155527.8
ENSMUST00000142129.8
ENSMUST00000093249.11
ENSMUST00000142475.3
ENSMUST00000128860.8
Cdh8
cadherin 8
chr7_+_127376267 0.30 ENSMUST00000144406.8
Setd1a
SET domain containing 1A
chr18_+_89215438 0.30 ENSMUST00000237110.2
Cd226
CD226 antigen
chr8_-_106723026 0.30 ENSMUST00000227363.2
ENSMUST00000081998.13
Dpep2
dipeptidase 2
chrX_-_42363663 0.29 ENSMUST00000016294.8
Tenm1
teneurin transmembrane protein 1
chr11_+_72098363 0.24 ENSMUST00000021158.4
Txndc17
thioredoxin domain containing 17
chr18_-_32082624 0.23 ENSMUST00000064016.6
Gpr17
G protein-coupled receptor 17
chr9_+_118307250 0.23 ENSMUST00000111763.8
Eomes
eomesodermin
chr8_+_85807566 0.21 ENSMUST00000140621.2
Wdr83os
WD repeat domain 83 opposite strand
chr7_-_126460820 0.19 ENSMUST00000129812.2
ENSMUST00000106342.8
Ino80e
INO80 complex subunit E
chr10_+_67371295 0.19 ENSMUST00000145754.8
ENSMUST00000145936.2
Egr2
early growth response 2
chr5_+_124250360 0.18 ENSMUST00000024470.13
ENSMUST00000119269.6
ENSMUST00000196627.5
ENSMUST00000199457.5
ENSMUST00000198505.2
Ogfod2
2-oxoglutarate and iron-dependent oxygenase domain containing 2
chr9_-_64633865 0.17 ENSMUST00000168366.2
Rab11a
RAB11A, member RAS oncogene family
chr17_-_35178208 0.16 ENSMUST00000172753.2
Hspa1b
heat shock protein 1B
chr4_+_140428777 0.16 ENSMUST00000138808.8
ENSMUST00000038893.6
Rcc2
regulator of chromosome condensation 2
chr7_+_10421716 0.16 ENSMUST00000117413.9
ENSMUST00000047809.11
Nlrp4b
NLR family, pyrin domain containing 4B
chr7_+_98092628 0.14 ENSMUST00000098274.5
Gucy2d
guanylate cyclase 2d
chr12_-_115531211 0.13 ENSMUST00000103536.4
Ighv8-11
immunoglobulin heavy variable V8-11
chr14_+_53370136 0.12 ENSMUST00000181793.3
Trav6n-6
T cell receptor alpha variable 6N-6
chr4_-_68872585 0.11 ENSMUST00000030036.6
Brinp1
bone morphogenic protein/retinoic acid inducible neural specific 1
chr2_+_109848224 0.05 ENSMUST00000150183.9
Ccdc34
coiled-coil domain containing 34
chr11_-_59484115 0.03 ENSMUST00000215626.2
Olfr223
olfactory receptor 223
chr3_-_89309944 0.03 ENSMUST00000057431.6
Lenep
lens epithelial protein
chr10_-_80861357 0.02 ENSMUST00000144640.2
Diras1
DIRAS family, GTP-binding RAS-like 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.7 GO:0072312 metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
1.0 3.9 GO:0042222 interleukin-1 biosynthetic process(GO:0042222)
0.5 4.4 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.4 3.0 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.4 1.4 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.3 2.6 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.3 2.3 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.3 1.4 GO:0060356 leucine import(GO:0060356)
0.2 3.7 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.2 1.0 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.2 1.3 GO:0030473 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.2 0.5 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 1.1 GO:0051012 microtubule sliding(GO:0051012)
0.2 0.6 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 8.3 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.5 GO:0019046 release from viral latency(GO:0019046)
0.1 1.3 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 1.4 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 2.5 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 2.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.2 GO:0021664 rhombomere formation(GO:0021594) rhombomere 3 formation(GO:0021660) rhombomere 5 morphogenesis(GO:0021664) rhombomere 5 formation(GO:0021666)
0.1 0.2 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.1 0.2 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.1 2.8 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 0.3 GO:0060369 positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.9 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 3.6 GO:0090501 RNA phosphodiester bond hydrolysis(GO:0090501)
0.0 1.6 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 3.9 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)
0.0 0.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 1.1 GO:0032674 regulation of interleukin-5 production(GO:0032674)
0.0 0.2 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.0 2.2 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 1.1 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 4.7 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.6 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.3 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.5 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.0 0.8 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.5 GO:0006301 postreplication repair(GO:0006301)
0.0 1.9 GO:0006672 ceramide metabolic process(GO:0006672)
0.0 0.7 GO:0043171 peptide catabolic process(GO:0043171)
0.0 1.1 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 1.8 GO:0008584 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 2.7 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 3.5 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 0.8 GO:0048286 lung alveolus development(GO:0048286)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.0 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.3 2.3 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.2 3.2 GO:0000243 commitment complex(GO:0000243)
0.2 4.1 GO:0005861 troponin complex(GO:0005861)
0.1 1.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 10.7 GO:0005581 collagen trimer(GO:0005581)
0.1 1.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 2.6 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 4.6 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 3.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.8 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 1.4 GO:0005921 gap junction(GO:0005921)
0.0 1.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.7 GO:0071565 nBAF complex(GO:0071565)
0.0 0.8 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828) postsynaptic recycling endosome(GO:0098837)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.8 GO:0016235 aggresome(GO:0016235)
0.0 3.6 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.3 GO:0072686 mitotic spindle(GO:0072686)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 10.7 GO:0033691 sialic acid binding(GO:0033691)
0.7 2.6 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.6 1.9 GO:0001729 ceramide kinase activity(GO:0001729)
0.6 3.9 GO:0004977 melanocortin receptor activity(GO:0004977)
0.5 3.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.4 4.1 GO:0031014 troponin T binding(GO:0031014)
0.4 3.6 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.2 0.9 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 1.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 0.8 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 3.5 GO:0008483 transaminase activity(GO:0008483)
0.1 0.6 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.6 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 1.3 GO:0043495 protein anchor(GO:0043495)
0.1 1.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.6 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 0.3 GO:1990188 euchromatin binding(GO:1990188)
0.1 1.5 GO:0042923 neuropeptide binding(GO:0042923)
0.0 9.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.5 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 4.7 GO:0051087 chaperone binding(GO:0051087)
0.0 2.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.1 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 1.6 GO:0070888 E-box binding(GO:0070888)
0.0 1.2 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 2.6 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 1.0 GO:0004601 peroxidase activity(GO:0004601)
0.0 3.7 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 1.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 7.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 11.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.9 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 2.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 5.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 1.1 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 3.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 3.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 3.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 10.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 4.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 2.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 3.9 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 1.1 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.0 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway