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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Ptf1a

Z-value: 1.25

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Transcription factors associated with Ptf1a

Gene Symbol Gene ID Gene Info
Ptf1a
ENSMUSG00000026735.3 Ptf1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Ptf1amm39_v1_chr2_+_19450443_194504740.291.4e-02Click!

Activity profile of Ptf1a motif

Sorted Z-values of Ptf1a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Ptf1a

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr12_-_114104740 13.63 ENSMUST00000103473.2
Ighv9-3
immunoglobulin heavy variable V9-3
chr7_+_28240262 12.83 ENSMUST00000119180.4
Sycn
syncollin
chr6_-_69626340 12.49 ENSMUST00000198328.2
Igkv4-53
immunoglobulin kappa variable 4-53
chr6_-_41291634 11.17 ENSMUST00000064324.12
Try5
trypsin 5
chr8_-_112417633 10.27 ENSMUST00000034435.7
Ctrb1
chymotrypsinogen B1
chr6_+_68233361 9.40 ENSMUST00000103320.3
Igkv14-111
immunoglobulin kappa variable 14-111
chr6_-_69584812 8.88 ENSMUST00000103359.3
Igkv4-55
immunoglobulin kappa variable 4-55
chr6_+_70549568 8.63 ENSMUST00000196940.2
ENSMUST00000103397.3
Igkv3-10
immunoglobulin kappa variable 3-10
chr14_-_63654478 7.86 ENSMUST00000014597.5
Blk
B lymphoid kinase
chr6_+_41279199 7.75 ENSMUST00000031913.5
Try4
trypsin 4
chr6_+_41024260 7.62 ENSMUST00000103263.3
Trbv2
T cell receptor beta, variable 2
chr6_-_136758716 6.95 ENSMUST00000078095.11
ENSMUST00000032338.10
Gucy2c
guanylate cyclase 2c
chr12_-_114263874 6.53 ENSMUST00000103482.2
ENSMUST00000194159.2
Ighv9-4
immunoglobulin heavy variable 9-4
chr2_-_34851561 6.37 ENSMUST00000028234.12
Traf1
TNF receptor-associated factor 1
chr11_+_66847446 6.32 ENSMUST00000211300.2
ENSMUST00000150220.2
Tmem238l
transmembrane protein 238 like
chr8_+_123920233 6.07 ENSMUST00000212773.2
Dpep1
dipeptidase 1
chr6_-_69394425 5.99 ENSMUST00000199160.2
Igkv4-61
immunoglobulin kappa chain variable 4-61
chr4_-_133615075 5.94 ENSMUST00000003741.16
ENSMUST00000105894.11
Rps6ka1
ribosomal protein S6 kinase polypeptide 1
chr6_-_70318164 5.84 ENSMUST00000103389.3
Igkv8-19
immunoglobulin kappa variable 8-19
chr12_-_114057841 5.79 ENSMUST00000103471.2
ENSMUST00000195884.2
Ighv9-1
immunoglobulin heavy variable 9-1
chr11_-_99045894 5.79 ENSMUST00000103134.4
Ccr7
chemokine (C-C motif) receptor 7
chr2_+_180367056 5.78 ENSMUST00000094218.4
Slc17a9
solute carrier family 17, member 9
chr6_+_41118120 5.71 ENSMUST00000103273.3
Trbv15
T cell receptor beta, variable 15
chr13_+_19528728 5.44 ENSMUST00000179181.3
Trgc4
T cell receptor gamma, constant 4
chr2_+_164611812 5.41 ENSMUST00000088248.13
ENSMUST00000001439.7
Ube2c
ubiquitin-conjugating enzyme E2C
chr5_-_121025645 4.99 ENSMUST00000086368.12
Oas1g
2'-5' oligoadenylate synthetase 1G
chr15_-_76501041 4.98 ENSMUST00000073428.7
Slc39a4
solute carrier family 39 (zinc transporter), member 4
chr12_-_114073050 4.70 ENSMUST00000103472.4
Ighv9-2
immunoglobulin heavy variable V9-2
chr7_+_103978678 4.70 ENSMUST00000180136.2
ENSMUST00000106847.9
Trim34b
tripartite motif-containing 34B
chr8_+_123920682 4.68 ENSMUST00000212409.2
Dpep1
dipeptidase 1
chr14_-_32907023 4.65 ENSMUST00000130509.10
ENSMUST00000061753.15
Wdfy4
WD repeat and FYVE domain containing 4
chr6_+_41435846 4.53 ENSMUST00000031910.8
Prss1
protease, serine 1 (trypsin 1)
chr7_-_130924021 4.19 ENSMUST00000046611.9
Cuzd1
CUB and zona pellucida-like domains 1
chr2_+_164790139 3.86 ENSMUST00000017881.3
Mmp9
matrix metallopeptidase 9
chr6_-_69162381 3.78 ENSMUST00000103344.3
Igkv4-74
immunoglobulin kappa variable 4-74
chr1_-_171434882 3.70 ENSMUST00000111277.2
ENSMUST00000004827.14
Ly9
lymphocyte antigen 9
chr12_-_115276219 3.66 ENSMUST00000103529.4
Ighv1-58
immunoglobulin heavy variable 1-58
chr7_-_97848688 3.58 ENSMUST00000098278.4
B3gnt6
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)
chr1_-_171434944 3.54 ENSMUST00000068878.14
Ly9
lymphocyte antigen 9
chr7_-_140793990 3.48 ENSMUST00000026573.7
ENSMUST00000170841.9
Lmntd2
lamin tail domain containing 2
chr6_+_41369290 3.43 ENSMUST00000049079.9
Gm5771
predicted gene 5771
chr8_+_82069177 3.36 ENSMUST00000213285.2
ENSMUST00000217122.2
ENSMUST00000215332.2
Inpp4b
inositol polyphosphate-4-phosphatase, type II
chr7_-_79492091 3.18 ENSMUST00000049004.8
Anpep
alanyl (membrane) aminopeptidase
chr1_+_36510670 3.17 ENSMUST00000153128.2
Cnnm4
cyclin M4
chr16_-_21980200 3.16 ENSMUST00000115379.2
Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr7_+_97100523 3.09 ENSMUST00000206658.2
Kctd14
potassium channel tetramerisation domain containing 14
chr12_-_114451189 3.03 ENSMUST00000103493.3
Ighv1-4
immunoglobulin heavy variable 1-4
chr6_+_41331039 3.02 ENSMUST00000072103.7
Try10
trypsin 10
chr6_-_115785695 3.00 ENSMUST00000081840.6
Rpl32
ribosomal protein L32
chr7_+_118199375 2.90 ENSMUST00000121744.9
Tmc5
transmembrane channel-like gene family 5
chr19_-_7218363 2.85 ENSMUST00000236769.2
Naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit
chrX_-_161747552 2.79 ENSMUST00000038769.3
S100g
S100 calcium binding protein G
chr14_-_32907446 2.75 ENSMUST00000159606.2
Wdfy4
WD repeat and FYVE domain containing 4
chr10_+_60182630 2.73 ENSMUST00000020301.14
ENSMUST00000105460.8
ENSMUST00000170507.8
Vsir
V-set immunoregulatory receptor
chr6_-_68784692 2.72 ENSMUST00000103334.4
Igkv4-90
immunoglobulin kappa chain variable 4-90
chr3_-_83749036 2.69 ENSMUST00000029623.11
Tlr2
toll-like receptor 2
chr9_+_20927271 2.63 ENSMUST00000086399.6
Icam1
intercellular adhesion molecule 1
chr14_-_51295099 2.33 ENSMUST00000227764.2
Rnase12
ribonuclease, RNase A family, 12 (non-active)
chr11_+_48691175 2.33 ENSMUST00000020640.8
Rack1
receptor for activated C kinase 1
chr4_-_63965161 2.32 ENSMUST00000107377.10
Tnc
tenascin C
chr11_-_74480870 2.19 ENSMUST00000145524.2
ENSMUST00000102521.9
Rap1gap2
RAP1 GTPase activating protein 2
chr5_-_99400698 2.15 ENSMUST00000031276.15
ENSMUST00000168092.8
Rasgef1b
RasGEF domain family, member 1B
chr15_-_77283286 2.13 ENSMUST00000175919.8
ENSMUST00000176074.9
Apol7a
apolipoprotein L 7a
chr10_+_94350687 2.07 ENSMUST00000065060.12
Tmcc3
transmembrane and coiled coil domains 3
chr9_+_59563872 2.05 ENSMUST00000215623.2
ENSMUST00000215660.2
ENSMUST00000217353.2
Pkm
pyruvate kinase, muscle
chr17_+_8144822 2.02 ENSMUST00000036370.8
Tagap
T cell activation Rho GTPase activating protein
chr14_-_21898992 2.01 ENSMUST00000124549.9
Comtd1
catechol-O-methyltransferase domain containing 1
chr9_+_59563838 1.92 ENSMUST00000163694.4
Pkm
pyruvate kinase, muscle
chr10_+_75047897 1.91 ENSMUST00000218766.2
Specc1l
sperm antigen with calponin homology and coiled-coil domains 1-like
chr9_+_59614877 1.82 ENSMUST00000128944.8
ENSMUST00000098661.10
Gramd2
GRAM domain containing 2
chr6_+_65567373 1.77 ENSMUST00000114236.2
Tnip3
TNFAIP3 interacting protein 3
chr19_-_7218512 1.70 ENSMUST00000025675.11
Naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit
chr19_-_9876745 1.68 ENSMUST00000237725.2
Incenp
inner centromere protein
chr6_-_69261303 1.66 ENSMUST00000103349.2
Igkv4-69
immunoglobulin kappa variable 4-69
chr9_+_108731884 1.63 ENSMUST00000239562.1
Slc26a6
solute carrier family 26, member 6
chr11_+_120653613 1.62 ENSMUST00000105046.4
Hmga1b
high mobility group AT-hook 1B
chr12_+_71062733 1.57 ENSMUST00000046305.12
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr16_-_44153288 1.45 ENSMUST00000136381.8
Sidt1
SID1 transmembrane family, member 1
chr11_-_6394352 1.32 ENSMUST00000093346.6
H2az2
H2A.Z histone variant 2
chr11_+_101215889 1.24 ENSMUST00000041095.14
ENSMUST00000107264.2
Aoc2
amine oxidase, copper containing 2 (retina-specific)
chr19_+_16413126 1.21 ENSMUST00000025602.4
Gna14
guanine nucleotide binding protein, alpha 14
chr18_-_80484066 1.20 ENSMUST00000161003.2
Ctdp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr17_+_21910767 1.18 ENSMUST00000072133.5
Gm10226
predicted gene 10226
chr13_-_61012185 1.17 ENSMUST00000091569.7
4930486L24Rik
RIKEN cDNA 4930486L24 gene
chr11_+_54582248 1.12 ENSMUST00000136494.2
Rapgef6
Rap guanine nucleotide exchange factor (GEF) 6
chr2_-_91780731 1.08 ENSMUST00000111303.2
Dgkz
diacylglycerol kinase zeta
chr3_+_107008867 1.06 ENSMUST00000038695.6
Kcna2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr12_+_112727089 1.06 ENSMUST00000063888.5
Pld4
phospholipase D family, member 4
chr14_+_52860023 1.04 ENSMUST00000103570.2
Trav5-1
T cell receptor alpha variable 5-1
chr11_-_97242842 1.03 ENSMUST00000093942.5
Gpr179
G protein-coupled receptor 179
chr17_+_29899420 1.01 ENSMUST00000130052.9
Cmtr1
cap methyltransferase 1
chr7_-_144136194 1.01 ENSMUST00000033394.8
Fadd
Fas (TNFRSF6)-associated via death domain
chr18_-_80484003 0.99 ENSMUST00000160434.3
Ctdp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr11_+_40624763 0.98 ENSMUST00000127382.2
Nudcd2
NudC domain containing 2
chr11_+_98337655 0.97 ENSMUST00000019456.5
Grb7
growth factor receptor bound protein 7
chr16_-_63684477 0.94 ENSMUST00000232654.2
ENSMUST00000064405.8
Epha3
Eph receptor A3
chr7_+_79939747 0.92 ENSMUST00000205864.2
Vps33b
vacuolar protein sorting 33B
chr11_+_40624466 0.92 ENSMUST00000020578.11
Nudcd2
NudC domain containing 2
chr7_+_18865610 0.91 ENSMUST00000165913.2
Fbxo46
F-box protein 46
chr4_-_88357112 0.79 ENSMUST00000132493.8
ENSMUST00000030221.3
ENSMUST00000151280.8
Hacd4
3-hydroxyacyl-CoA dehydratase 4
chr5_-_66211842 0.77 ENSMUST00000200852.4
Rbm47
RNA binding motif protein 47
chrX_+_159173680 0.76 ENSMUST00000112408.9
ENSMUST00000112402.8
ENSMUST00000112401.8
ENSMUST00000112400.8
ENSMUST00000112405.9
ENSMUST00000112404.9
ENSMUST00000146805.8
Adgrg2
adhesion G protein-coupled receptor G2
chr11_-_6394385 0.76 ENSMUST00000109737.9
H2az2
H2A.Z histone variant 2
chr11_-_118246566 0.74 ENSMUST00000155707.3
Timp2
tissue inhibitor of metalloproteinase 2
chr6_-_69220672 0.74 ENSMUST00000196201.2
Igkv4-71
immunoglobulin kappa chain variable 4-71
chr8_+_72662437 0.70 ENSMUST00000110002.8
ENSMUST00000125802.8
ENSMUST00000131544.8
Zfp882
Zfp617
zinc finger protein 882
zinc finger protein 617
chr7_-_142628298 0.67 ENSMUST00000148715.8
Trpm5
transient receptor potential cation channel, subfamily M, member 5
chr2_+_22232314 0.62 ENSMUST00000044749.14
Myo3a
myosin IIIA
chr5_+_34683141 0.61 ENSMUST00000125817.8
ENSMUST00000067638.14
Sh3bp2
SH3-domain binding protein 2
chr5_+_143450329 0.59 ENSMUST00000045593.12
Daglb
diacylglycerol lipase, beta
chr11_-_73348284 0.59 ENSMUST00000121209.3
ENSMUST00000127789.3
Olfr380
olfactory receptor 380
chr4_+_114945905 0.58 ENSMUST00000171877.8
ENSMUST00000177647.8
ENSMUST00000106548.9
ENSMUST00000030488.3
Pdzk1ip1
PDZK1 interacting protein 1
chr11_-_118246332 0.57 ENSMUST00000017610.10
Timp2
tissue inhibitor of metalloproteinase 2
chr2_-_125624754 0.53 ENSMUST00000053699.13
Secisbp2l
SECIS binding protein 2-like
chr19_+_40648182 0.52 ENSMUST00000112231.9
ENSMUST00000127828.8
Entpd1
ectonucleoside triphosphate diphosphohydrolase 1
chr16_-_63684425 0.51 ENSMUST00000232049.2
Epha3
Eph receptor A3
chr9_-_85631361 0.49 ENSMUST00000039213.15
Ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr4_-_36056726 0.49 ENSMUST00000108124.4
Lingo2
leucine rich repeat and Ig domain containing 2
chr12_+_117497478 0.48 ENSMUST00000220781.2
Rapgef5
Rap guanine nucleotide exchange factor (GEF) 5
chr14_-_8123295 0.45 ENSMUST00000225775.2
ENSMUST00000224877.2
ENSMUST00000090591.4
Il3ra
interleukin 3 receptor, alpha chain
chr10_+_42554888 0.44 ENSMUST00000040718.6
Ostm1
osteopetrosis associated transmembrane protein 1
chr10_-_75768302 0.44 ENSMUST00000120281.8
ENSMUST00000000924.13
Mmp11
matrix metallopeptidase 11
chr7_-_4535403 0.41 ENSMUST00000094897.5
Dnaaf3
dynein, axonemal assembly factor 3
chr9_-_112016834 0.40 ENSMUST00000111872.9
ENSMUST00000164754.9
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr19_+_32463151 0.37 ENSMUST00000025827.10
Minpp1
multiple inositol polyphosphate histidine phosphatase 1
chr6_-_5256225 0.35 ENSMUST00000125686.8
Pon3
paraoxonase 3
chr6_-_68968278 0.35 ENSMUST00000197966.2
Igkv4-81
immunoglobulin kappa variable 4-81
chr11_+_97206542 0.34 ENSMUST00000019026.10
ENSMUST00000132168.2
Mrpl45
mitochondrial ribosomal protein L45
chrX_-_162859429 0.32 ENSMUST00000134272.2
Siah1b
siah E3 ubiquitin protein ligase 1B
chr2_+_153742294 0.24 ENSMUST00000088955.12
ENSMUST00000135501.3
Bpifb6
BPI fold containing family B, member 6
chr4_-_43706566 0.23 ENSMUST00000055401.2
Olfr71
olfactory receptor 71
chr11_+_72332167 0.20 ENSMUST00000045633.6
Mybbp1a
MYB binding protein (P160) 1a
chr11_-_102076028 0.18 ENSMUST00000107156.9
ENSMUST00000021297.6
Lsm12
LSM12 homolog
chr11_+_98489117 0.15 ENSMUST00000142268.3
Lrrc3c
leucine rich repeat containing 3C
chr1_+_151074199 0.09 ENSMUST00000225273.2
Gm47995
predicted gene, 47995
chr9_-_106353571 0.07 ENSMUST00000123555.8
ENSMUST00000125850.2
Parp3
poly (ADP-ribose) polymerase family, member 3
chr11_-_70213348 0.07 ENSMUST00000019051.3
Alox12e
arachidonate lipoxygenase, epidermal
chr10_-_126737185 0.05 ENSMUST00000168520.3
ENSMUST00000026504.13
Atp23
ATP23 metallopeptidase and ATP synthase assembly factor homolog
chr17_+_25527616 0.04 ENSMUST00000015267.5
Prss28
protease, serine 28
chr11_+_49138278 0.04 ENSMUST00000109194.2
Mgat1
mannoside acetylglucosaminyltransferase 1
chr2_-_93787383 0.04 ENSMUST00000148314.3
Gm13889
predicted gene 13889
chr11_+_101221431 0.01 ENSMUST00000103105.10
Aoc3
amine oxidase, copper containing 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 10.8 GO:0016999 antibiotic metabolic process(GO:0016999)
1.9 5.8 GO:0097021 regulation of tolerance induction to self antigen(GO:0002649) lymphocyte migration into lymphoid organs(GO:0097021) positive regulation of thymocyte migration(GO:2000412) regulation of dendritic cell dendrite assembly(GO:2000547)
1.3 3.9 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
1.0 5.0 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.9 2.7 GO:0042495 positive regulation of interleukin-18 production(GO:0032741) detection of triacyl bacterial lipopeptide(GO:0042495) response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.7 5.4 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.7 5.9 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.6 2.3 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.6 2.3 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.5 1.6 GO:0046724 oxalic acid secretion(GO:0046724)
0.5 1.4 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.5 2.7 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.5 7.2 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.4 4.0 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.4 2.6 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.4 1.3 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.3 1.0 GO:2000451 positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451)
0.2 37.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.2 37.9 GO:0007586 digestion(GO:0007586)
0.2 1.0 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.2 2.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.2 51.1 GO:0002377 immunoglobulin production(GO:0002377)
0.2 3.2 GO:0070166 magnesium ion transport(GO:0015693) enamel mineralization(GO:0070166)
0.2 1.1 GO:0021633 optic nerve structural organization(GO:0021633)
0.2 1.6 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.2 4.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.2 3.4 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.2 3.2 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.1 1.5 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.9 GO:0070889 platelet alpha granule organization(GO:0070889)
0.1 6.9 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.1 0.4 GO:0038156 interleukin-3-mediated signaling pathway(GO:0038156)
0.1 1.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 7.9 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.1 1.8 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.1 0.4 GO:0046226 coumarin catabolic process(GO:0046226)
0.1 0.5 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.1 0.8 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 3.0 GO:1903146 regulation of mitophagy(GO:1903146)
0.1 0.5 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 1.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 1.9 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 1.0 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.6 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 6.4 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 1.1 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.8 GO:0042761 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 1.0 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 4.2 GO:0031638 zymogen activation(GO:0031638)
0.0 0.6 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 3.2 GO:0051028 mRNA transport(GO:0051028)
0.0 0.4 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.4 GO:0070286 motile cilium assembly(GO:0044458) axonemal dynein complex assembly(GO:0070286)
0.0 0.0 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:1902912 pyruvate kinase complex(GO:1902912)
0.9 2.7 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.8 2.3 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
0.3 37.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.3 6.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 4.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.2 5.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 12.8 GO:0030667 secretory granule membrane(GO:0030667)
0.1 1.7 GO:0000801 central element(GO:0000801)
0.1 1.0 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 1.2 GO:0031983 vesicle lumen(GO:0031983)
0.1 2.3 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.9 GO:0071439 clathrin complex(GO:0071439)
0.1 0.2 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 1.6 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 2.2 GO:0051233 spindle midzone(GO:0051233)
0.0 1.0 GO:0044292 dendrite terminus(GO:0044292)
0.0 2.6 GO:0001772 immunological synapse(GO:0001772)
0.0 9.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 3.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 8.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.6 GO:0032426 stereocilium tip(GO:0032426)
0.0 64.2 GO:0005615 extracellular space(GO:0005615)
0.0 5.4 GO:0005819 spindle(GO:0005819)
0.0 4.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.9 GO:0000776 kinetochore(GO:0000776)
0.0 1.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.0 GO:0010494 cytoplasmic stress granule(GO:0010494)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 10.8 GO:0070573 metallodipeptidase activity(GO:0070573)
0.9 2.7 GO:0042497 triacyl lipopeptide binding(GO:0042497)
0.8 3.4 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.8 4.0 GO:0004743 pyruvate kinase activity(GO:0004743)
0.7 2.2 GO:0001096 TFIIF-class transcription factor binding(GO:0001096)
0.5 4.6 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.4 6.4 GO:0031996 thioesterase binding(GO:0031996)
0.4 1.3 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.4 5.0 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.4 5.8 GO:0019957 C-C chemokine binding(GO:0019957)
0.4 2.8 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.3 2.8 GO:0005499 vitamin D binding(GO:0005499)
0.3 37.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.3 1.6 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
0.3 6.9 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 1.5 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.2 2.3 GO:0045545 syndecan binding(GO:0045545)
0.2 41.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 1.0 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.2 1.0 GO:0035877 death effector domain binding(GO:0035877)
0.2 0.8 GO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.2 3.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.4 GO:0004912 interleukin-3 receptor activity(GO:0004912) interleukin-3 binding(GO:0019978)
0.1 1.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 1.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 3.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 5.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 5.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 5.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 3.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.4 GO:0052743 inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.1 7.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.4 GO:0004063 aryldialkylphosphatase activity(GO:0004063)
0.1 8.9 GO:0003823 antigen binding(GO:0003823)
0.1 3.6 GO:0008378 galactosyltransferase activity(GO:0008378)
0.1 1.1 GO:0001727 lipid kinase activity(GO:0001727)
0.1 1.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.5 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.1 0.5 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 1.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 1.1 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 1.6 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 1.2 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 1.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 2.3 GO:0004540 ribonuclease activity(GO:0004540)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 2.6 GO:0005178 integrin binding(GO:0005178)
0.0 3.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.0 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 1.2 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.1 GO:0051082 unfolded protein binding(GO:0051082)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 14.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 5.9 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 7.4 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 2.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.7 PID AURORA B PATHWAY Aurora B signaling
0.0 3.2 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.0 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.6 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.4 PID IL3 PATHWAY IL3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 20.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.3 2.7 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.3 5.4 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.2 5.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.2 3.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 7.9 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 5.9 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 5.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 1.0 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 1.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 3.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 1.3 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 2.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 3.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides