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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Rad21_Smc3

Z-value: 1.21

Motif logo

Transcription factors associated with Rad21_Smc3

Gene Symbol Gene ID Gene Info
ENSMUSG00000022314.11 Rad21
ENSMUSG00000024974.11 Smc3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Smc3mm39_v1_chr19_+_53588808_535888690.473.1e-05Click!
Rad21mm39_v1_chr15_-_51855073_518551590.458.0e-05Click!

Activity profile of Rad21_Smc3 motif

Sorted Z-values of Rad21_Smc3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Rad21_Smc3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr9_+_106088798 9.21 ENSMUST00000216850.2
twinfilin actin binding protein 2
chr14_+_53903370 8.75 ENSMUST00000181768.3
T cell receptor alpha variable 3-3
chr4_-_129467430 8.28 ENSMUST00000102596.8
lymphocyte protein tyrosine kinase
chr1_-_85664246 8.21 ENSMUST00000064788.14
RIKEN cDNA A630001G21 gene
chr8_+_106412905 8.14 ENSMUST00000213019.2
capping protein regulator and myosin 1 linker 2
chr14_+_53828314 7.79 ENSMUST00000103654.3
T cell receptor alpha variable 9-2
chr14_+_53698556 7.09 ENSMUST00000181728.3
T cell receptor alpha variable 7-4
chr14_+_53725502 7.08 ENSMUST00000103581.6
T cell receptor alpha variable 9-1
chr16_-_10603389 7.05 ENSMUST00000229866.2
ENSMUST00000038099.6
suppressor of cytokine signaling 1
chr10_-_77879414 6.85 ENSMUST00000145975.8
ENSMUST00000130972.8
ENSMUST00000128241.8
ENSMUST00000155021.8
ENSMUST00000140636.8
ENSMUST00000148469.8
ENSMUST00000019257.15
ENSMUST00000105395.9
ENSMUST00000156417.8
ENSMUST00000105396.9
ENSMUST00000154374.2
autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)
chr14_+_53468890 6.63 ENSMUST00000177705.3
T cell receptor alpha variable 9N-3
chr15_-_75620060 6.60 ENSMUST00000062002.6
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)
chr2_-_117173190 6.58 ENSMUST00000173541.8
ENSMUST00000172901.8
ENSMUST00000173252.2
RAS guanyl releasing protein 1
chr6_+_41090484 6.45 ENSMUST00000103267.3
T cell receptor beta, variable 12-1
chr2_+_29509704 6.43 ENSMUST00000095087.11
ENSMUST00000091146.12
ENSMUST00000102872.11
ENSMUST00000147755.10
Rap guanine nucleotide exchange factor (GEF) 1
chr7_+_25386418 6.13 ENSMUST00000002678.10
transforming growth factor, beta 1
chr5_+_137639538 6.10 ENSMUST00000177466.8
ENSMUST00000166099.3
sin3 associated polypeptide
chr14_+_53859114 5.95 ENSMUST00000103657.6
T cell receptor alpha variable 12-3
chr11_+_68322945 5.92 ENSMUST00000021283.8
phosphoinositide-3-kinase regulatory subunit 5
chr3_-_95049655 5.81 ENSMUST00000013851.4
tumor necrosis factor, alpha-induced protein 8-like 2
chr14_+_53853772 5.67 ENSMUST00000180972.3
T cell receptor alpha variable 12-2
chr14_+_53478202 5.65 ENSMUST00000179583.3
T cell receptor alpha variable 12N-3
chr19_+_42024439 5.63 ENSMUST00000238137.2
ENSMUST00000026172.3
ankyrin repeat domain 2 (stretch responsive muscle)
chr14_+_53209905 5.55 ENSMUST00000196023.2
T cell receptor alpha variable 3D-3
chr14_+_53583346 5.44 ENSMUST00000103632.4
T cell receptor alpha variable 8n-2
chr14_+_53007210 5.42 ENSMUST00000178768.4
T cell receptor alpha variable 7D-4
chr14_+_53157900 5.40 ENSMUST00000178252.3
T cell receptor alpha variable 9D-3
chr14_+_53521042 5.39 ENSMUST00000197557.2
T cell receptor alpha variable 3N-3
chr14_+_53913598 5.36 ENSMUST00000103662.6
T cell receptor alpha variable 9-4
chr14_+_53680701 5.19 ENSMUST00000177622.4
T cell receptor alpha variable 7-3
chr14_+_53531798 5.16 ENSMUST00000103626.3
T cell receptor alpha variable 9N-4
chr6_-_71376277 5.10 ENSMUST00000149415.2
required for meiotic nuclear division 5 homolog A
chr14_+_53628092 5.10 ENSMUST00000103636.4
T cell receptor alpha variable 7-2
chr14_+_52860023 5.07 ENSMUST00000103570.2
T cell receptor alpha variable 5-1
chr14_+_53743184 4.92 ENSMUST00000103583.5
T cell receptor alpha variable 10
chr12_-_84923252 4.90 ENSMUST00000163189.8
ENSMUST00000110254.9
ENSMUST00000002073.13
latent transforming growth factor beta binding protein 2
chr14_+_54119038 4.69 ENSMUST00000103676.9
ENSMUST00000187163.2
T cell receptor delta variable 1
chr9_-_44145280 4.66 ENSMUST00000205968.2
ENSMUST00000206147.2
ENSMUST00000037644.8
Casitas B-lineage lymphoma
chr14_+_53220658 4.63 ENSMUST00000200548.2
T cell receptor alpha variable 9D-4
chr14_+_53775648 4.61 ENSMUST00000200115.2
ENSMUST00000103650.3
T cell receptor alpha variable 12-1
chr14_+_54043954 4.56 ENSMUST00000103672.9
ENSMUST00000186545.2
T cell receptor alpha variable 17
chr14_+_53015904 4.54 ENSMUST00000103580.4
T cell receptor alpha variable 8D-1
chr14_+_54014387 4.53 ENSMUST00000103670.4
T cell receptor alpha variable 3-4
chr14_+_53061814 4.52 ENSMUST00000103648.4
T cell receptor alpha variable 11D
chr14_+_53556255 4.49 ENSMUST00000179607.3
T cell receptor alpha variable 6N-7
chr1_+_135060431 4.42 ENSMUST00000187985.7
ENSMUST00000049449.11
protein tyrosine phosphatase, non-receptor type 7
chr14_+_53153256 4.34 ENSMUST00000197007.2
ENSMUST00000103593.3
T cell receptor alpha variable 12D-2
chr17_+_34354556 4.32 ENSMUST00000236322.2
ENSMUST00000237402.2
histocompatibility 2, class II, locus DMa
chr14_+_53029773 4.31 ENSMUST00000178426.4
T cell receptor alpha variable 9D-1
chr9_-_44145309 4.25 ENSMUST00000206720.2
Casitas B-lineage lymphoma
chr14_+_53954133 4.24 ENSMUST00000103641.6
T cell receptor alpha variable 7-6
chr4_-_126362372 4.19 ENSMUST00000097888.10
ENSMUST00000239399.2
argonaute RISC catalytic subunit 1
chr5_-_136596299 4.16 ENSMUST00000004097.16
cut-like homeobox 1
chr18_-_77802145 4.13 ENSMUST00000237203.2
RIKEN cDNA 8030462N17 gene
chr14_+_53562089 4.08 ENSMUST00000178100.3
T cell receptor alpha variable 7N-6
chr17_+_34423054 3.96 ENSMUST00000138491.2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr14_+_52892115 3.95 ENSMUST00000198019.2
T cell receptor alpha variable 7-1
chr14_+_52921421 3.93 ENSMUST00000200127.2
T cell receptor alpha variable 7D-2
chr14_+_53210216 3.91 ENSMUST00000103599.3
T cell receptor alpha variable 3D-3
chr8_+_112262729 3.91 ENSMUST00000172856.8
zinc and ring finger 1
chr16_+_48251600 3.86 ENSMUST00000023330.8
microrchidia 1
chr14_+_53666165 3.85 ENSMUST00000180549.3
T cell receptor alpha variable 6-3
chr14_+_53239170 3.80 ENSMUST00000179701.2
T cell receptor alpha variable 5D-4
chr14_+_53392969 3.67 ENSMUST00000198682.2
ENSMUST00000103587.4
T cell receptor alpha variable 12N-1
chr19_+_7394951 3.67 ENSMUST00000159348.3
RIKEN cDNA 2700081O15 gene
chr9_-_57552844 3.65 ENSMUST00000216979.2
ENSMUST00000034863.8
c-src tyrosine kinase
chr8_-_13304154 3.65 ENSMUST00000204916.3
ENSMUST00000033825.11
ADP-ribosylhydrolase like 1
chr19_+_6450553 3.55 ENSMUST00000146831.8
ENSMUST00000035716.15
ENSMUST00000138555.8
ENSMUST00000167240.8
RAS, guanyl releasing protein 2
chr14_+_53384376 3.55 ENSMUST00000199753.2
T cell receptor alpha variable 7N-5
chr14_+_53521353 3.54 ENSMUST00000103625.3
T cell receptor alpha variable 3N-3
chr15_+_74593041 3.45 ENSMUST00000070923.3
thioesterase superfamily member 6
chr17_-_56343625 3.41 ENSMUST00000003268.11
SH3-domain GRB2-like 1
chr7_+_16044336 3.41 ENSMUST00000136781.2
BCL2 binding component 3
chr18_+_34910064 3.36 ENSMUST00000043775.9
ENSMUST00000224715.2
KDM3B lysine (K)-specific demethylase 3B
chr17_-_56343531 3.33 ENSMUST00000233803.2
SH3-domain GRB2-like 1
chr12_-_100995305 3.32 ENSMUST00000068411.5
coiled-coil domain containing 88C
chr18_-_49888606 3.30 ENSMUST00000025383.10
ENSMUST00000163590.9
DTW domain containing 2
chr12_-_100995242 3.28 ENSMUST00000085096.10
coiled-coil domain containing 88C
chr7_-_44785480 3.26 ENSMUST00000211246.2
ENSMUST00000210197.2
FMS-like tyrosine kinase 3 ligand
chr4_-_132073048 3.25 ENSMUST00000084250.11
regulator of chromosome condensation 1
chr5_-_137739863 3.22 ENSMUST00000061789.14
neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1
chr14_+_52990824 3.22 ENSMUST00000180717.3
ENSMUST00000183820.2
T cell receptor alpha variable 6D-4
chr4_-_132072988 3.20 ENSMUST00000030726.13
regulator of chromosome condensation 1
chr17_-_34109513 3.19 ENSMUST00000173386.2
ENSMUST00000114361.9
ENSMUST00000173492.9
kinesin family member C1
chr14_+_53081922 3.18 ENSMUST00000181360.3
ENSMUST00000183652.2
T cell receptor alpha variable 12D-1
chr19_+_5928649 3.16 ENSMUST00000136833.8
ENSMUST00000141362.2
solute carrier family 25, member 45
chr2_+_172821620 3.16 ENSMUST00000109125.8
ENSMUST00000109126.5
ENSMUST00000050442.15
SPO11 initiator of meiotic double stranded breaks
chr14_+_53707213 3.13 ENSMUST00000103643.4
T cell receptor alpha variable 8-1
chr16_-_20245071 3.06 ENSMUST00000115547.9
ENSMUST00000096199.5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr14_+_53167246 3.03 ENSMUST00000177703.3
T cell receptor alpha variable 12D-3
chr5_-_137739364 3.00 ENSMUST00000149512.3
neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1
chr5_+_137517140 2.99 ENSMUST00000031727.10
GRB10 interacting GYF protein 1
chr2_-_91793847 2.96 ENSMUST00000028667.10
diacylglycerol kinase zeta
chr16_-_20245138 2.95 ENSMUST00000079158.13
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr1_+_52669849 2.92 ENSMUST00000165859.8
nuclear envelope integral membrane protein 2
chr14_+_52818032 2.90 ENSMUST00000103569.3
T cell receptor alpha variable 3-1
chr14_+_53048391 2.90 ENSMUST00000103646.5
T cell receptor alpha variable 10D
chr14_+_52875909 2.87 ENSMUST00000103571.2
T cell receptor alpha variable 6-1
chr17_+_27136065 2.85 ENSMUST00000078961.6
kinesin family member C5B
chr14_+_53550361 2.83 ENSMUST00000179997.2
T cell receptor alpha variable 5N-4
chr7_+_16043502 2.82 ENSMUST00000002152.13
BCL2 binding component 3
chr7_-_126616472 2.78 ENSMUST00000206416.2
ENSMUST00000162069.3
ENSMUST00000200948.2
ENSMUST00000202798.2
PAXIP1 associated glutamate rich protein 1A
predicted gene 42742
chr8_-_13304068 2.78 ENSMUST00000168498.8
ADP-ribosylhydrolase like 1
chr14_+_53941464 2.75 ENSMUST00000103664.6
T cell receptor alpha variable 5-4
chr14_+_53279810 2.72 ENSMUST00000198439.5
ENSMUST00000103605.3
T cell receptor alpha variable 8D-2
chr14_+_53440579 2.69 ENSMUST00000198913.5
ENSMUST00000180097.2
T cell receptor alpha variable 9N-2
chr19_+_6450641 2.61 ENSMUST00000113467.2
RAS, guanyl releasing protein 2
chr7_-_92523396 2.57 ENSMUST00000209074.2
ENSMUST00000208356.2
ENSMUST00000032877.11
DNA damage-induced apoptosis suppressor
chr19_-_5538370 2.56 ENSMUST00000124334.8
MUS81 structure-specific endonuclease subunit
chr10_+_17931459 2.55 ENSMUST00000154718.8
ENSMUST00000126390.8
ENSMUST00000164556.8
ENSMUST00000150029.8
RalBP1 associated Eps domain containing protein
chr1_-_38168697 2.55 ENSMUST00000027251.12
REV1, DNA directed polymerase
chr5_-_143301113 2.55 ENSMUST00000046418.3
RIKEN cDNA E130309D02 gene
chr14_+_55842002 2.54 ENSMUST00000138037.2
interferon regulatory factor 9
chr12_-_26465253 2.54 ENSMUST00000020971.14
ring finger protein 144A
chr19_-_24257904 2.52 ENSMUST00000081333.11
frataxin
chr7_-_44785815 2.51 ENSMUST00000146760.7
FMS-like tyrosine kinase 3 ligand
chr5_+_144705346 2.46 ENSMUST00000128550.8
transformation/transcription domain-associated protein
chr14_+_53947359 2.43 ENSMUST00000103638.6
T cell receptor alpha variable 6-7-DV9
chr5_+_150597204 2.43 ENSMUST00000202170.4
ENSMUST00000016569.11
PDS5 cohesin associated factor B
chrX_-_101232978 2.40 ENSMUST00000033683.8
ribosomal protein S4, X-linked
chr17_+_27904155 2.39 ENSMUST00000231669.2
ENSMUST00000097360.3
ENSMUST00000231236.2
protein kinase C and casein kinase substrate in neurons 1
chr12_-_26465130 2.39 ENSMUST00000222082.2
ENSMUST00000062149.6
ring finger protein 144A
chr2_-_33321306 2.37 ENSMUST00000113158.8
zinc finger and BTB domain containing 34
chr14_+_53328803 2.37 ENSMUST00000103609.2
T cell receptor alpha variable 7N-4
chr13_+_51254852 2.35 ENSMUST00000095797.6
spindlin 1
chr16_-_10994135 2.32 ENSMUST00000037633.16
zinc finger CCCH type containing 7 A
chr11_-_45835737 2.30 ENSMUST00000129820.8
U7 snRNP-specific Sm-like protein LSM11
chr19_+_46293210 2.29 ENSMUST00000236591.2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr18_-_10610048 2.28 ENSMUST00000115864.8
ENSMUST00000145320.2
ENSMUST00000097670.10
establishment of sister chromatid cohesion N-acetyltransferase 1
chr5_+_64317550 2.28 ENSMUST00000101195.9
TBC1 domain family, member 1
chr1_-_133537953 2.28 ENSMUST00000164574.2
ENSMUST00000166291.8
ENSMUST00000164096.2
ENSMUST00000166915.8
small nuclear ribonucleoprotein E
chr14_+_53257873 2.27 ENSMUST00000196756.2
T cell receptor alpha variable 7D-6
chr17_-_32074754 2.27 ENSMUST00000024839.6
salt inducible kinase 1
chr5_+_137516810 2.26 ENSMUST00000197624.5
GRB10 interacting GYF protein 1
chr5_+_120787253 2.25 ENSMUST00000156722.2
RAS protein activator like 1 (GAP1 like)
chr14_+_44162791 2.24 ENSMUST00000160298.2
predicted gene 8113
chr15_+_100659622 2.22 ENSMUST00000023776.13
solute carrier family 4 (anion exchanger), member 8
chr18_-_10610332 2.19 ENSMUST00000025142.13
establishment of sister chromatid cohesion N-acetyltransferase 1
chr5_+_115644727 2.19 ENSMUST00000067268.15
ENSMUST00000086523.7
ENSMUST00000212819.3
paxillin
chr2_+_90927053 2.19 ENSMUST00000132741.3
spleen focus forming virus (SFFV) proviral integration oncogene
chr8_+_88999031 2.18 ENSMUST00000169037.9
adenylate cyclase 7
chr18_-_77801624 2.18 ENSMUST00000074653.6
RIKEN cDNA 8030462N17 gene
chr14_+_53129643 2.18 ENSMUST00000199746.5
ENSMUST00000178824.2
T cell receptor alpha variable 9D-2
chr5_+_150597292 2.18 ENSMUST00000038900.15
PDS5 cohesin associated factor B
chr6_+_47812584 2.17 ENSMUST00000079881.11
ENSMUST00000114598.3
zinc finger protein 398
chr18_-_53877579 2.15 ENSMUST00000049811.8
ENSMUST00000237062.2
centrosomal protein 120
chr8_-_13304096 2.14 ENSMUST00000171619.2
ADP-ribosylhydrolase like 1
chr16_+_16714333 2.11 ENSMUST00000027373.12
ENSMUST00000232247.2
protein phosphatase 1F (PP2C domain containing)
chr7_-_126625657 2.11 ENSMUST00000205568.2
MYC-associated zinc finger protein (purine-binding transcription factor)
chr5_+_114845821 2.09 ENSMUST00000094441.11
trichoplein, keratin filament binding
chr7_-_142050663 2.08 ENSMUST00000238347.2
proline rich 33
chr14_+_53464230 2.04 ENSMUST00000196674.2
ENSMUST00000103619.3
T cell receptor alpha variable 12N-2
chr7_-_126625617 2.03 ENSMUST00000032916.6
MYC-associated zinc finger protein (purine-binding transcription factor)
chr9_+_123307758 1.97 ENSMUST00000026269.4
LIM domains containing 1
chr17_+_48761916 1.97 ENSMUST00000074574.13
unc-5 family C-terminal like
chr1_-_143578542 1.96 ENSMUST00000018337.9
cell division cycle 73, Paf1/RNA polymerase II complex component
chr3_-_95125002 1.96 ENSMUST00000107209.8
GA repeat binding protein, beta 2
chr16_-_20244631 1.96 ENSMUST00000077867.10
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr7_+_108533613 1.96 ENSMUST00000033342.7
eukaryotic translation initiation factor 3, subunit F
chr8_+_22682816 1.96 ENSMUST00000033866.9
vacuolar protein sorting 36
chr7_-_126625739 1.95 ENSMUST00000205461.2
MYC-associated zinc finger protein (purine-binding transcription factor)
chr5_+_115373895 1.94 ENSMUST00000081497.13
processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)
chr5_-_136164840 1.92 ENSMUST00000150406.2
ENSMUST00000006301.11
leucine-rich repeats and WD repeat domain containing 1
chr1_+_150268544 1.90 ENSMUST00000124973.9
translocated promoter region, nuclear basket protein
chr12_+_113120023 1.89 ENSMUST00000049271.13
tubulin epsilon and delta complex 1
chr8_+_70735477 1.86 ENSMUST00000087467.12
ENSMUST00000140212.8
ENSMUST00000110124.9
homer scaffolding protein 3
chr13_+_35925296 1.84 ENSMUST00000163595.3
chromodomain protein, Y chromosome-like
chr1_-_92576563 1.82 ENSMUST00000053144.4
otospiralin
chr12_-_100995102 1.81 ENSMUST00000223097.2
coiled-coil domain containing 88C
chr14_+_53245069 1.79 ENSMUST00000178650.3
T cell receptor alpha variable 6D-7
chr3_-_105594865 1.78 ENSMUST00000090680.11
DEAD box helicase 20
chr19_-_36034740 1.75 ENSMUST00000164639.8
ENSMUST00000166074.2
ENSMUST00000099505.4
5-hydroxytryptamine (serotonin) receptor 7
chr8_-_123159663 1.75 ENSMUST00000017604.10
cytochrome b-245, alpha polypeptide
chr10_-_126866658 1.74 ENSMUST00000120547.2
ENSMUST00000152054.8
Ts translation elongation factor, mitochondrial
chr19_+_57349112 1.74 ENSMUST00000036407.6
family with sequence similarity 160, member B1
chr5_+_64316771 1.74 ENSMUST00000043893.13
TBC1 domain family, member 1
chr14_+_45567245 1.74 ENSMUST00000022380.9
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr13_-_55684317 1.73 ENSMUST00000021956.9
ENSMUST00000224765.2
DEAD box helicase 41
chr11_-_69470139 1.71 ENSMUST00000048139.12
WD repeat containing, antisense to Trp53
chr4_-_149221998 1.71 ENSMUST00000176124.8
ENSMUST00000177408.2
ENSMUST00000105695.2
centromere protein S
chr3_-_96501443 1.70 ENSMUST00000145001.2
ENSMUST00000091924.10
polymerase (RNA) III (DNA directed) polypeptide G like
chr7_+_103893658 1.69 ENSMUST00000106849.9
ENSMUST00000060315.12
tripartite motif-containing 34A
chr6_+_120813199 1.68 ENSMUST00000009256.4
BCL2-like 13 (apoptosis facilitator)
chr16_-_90841360 1.68 ENSMUST00000118522.8
PAX3 and PAX7 binding protein 1
chr8_-_123159639 1.67 ENSMUST00000212600.2
cytochrome b-245, alpha polypeptide
chr15_-_96358612 1.66 ENSMUST00000047835.8
SR-related CTD-associated factor 11
chr7_+_49428082 1.64 ENSMUST00000032715.13
protein arginine N-methyltransferase 3
chr4_-_149222057 1.64 ENSMUST00000030813.10
centromere protein S
chr7_-_28071658 1.64 ENSMUST00000094644.11
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr12_+_24758724 1.62 ENSMUST00000153058.8
ribonucleotide reductase M2
chr8_-_25592001 1.61 ENSMUST00000128715.8
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr17_+_56920389 1.61 ENSMUST00000080492.7
ribosomal protein L36
chr13_-_8921732 1.61 ENSMUST00000054251.13
ENSMUST00000176813.8
ENSMUST00000175958.2
WD repeat domain 37
chr12_+_24758968 1.60 ENSMUST00000154588.2
ribonucleotide reductase M2
chr7_-_46360066 1.60 ENSMUST00000143082.4
serum amyloid A-like 1
chr6_+_59185846 1.59 ENSMUST00000062626.4
tigger transposable element derived 2
chr7_-_126859790 1.59 ENSMUST00000035276.5
dCTP pyrophosphatase 1
chrX_-_139501246 1.59 ENSMUST00000112996.9
TSC22 domain family, member 3
chr18_-_38068456 1.58 ENSMUST00000080033.7
ENSMUST00000115631.8
ENSMUST00000115634.8
diaphanous related formin 1
chr12_-_8351954 1.58 ENSMUST00000220073.2
ENSMUST00000037313.6
growth differentiation factor 7

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.1 GO:2000813 negative regulation of barbed-end actin filament capping(GO:2000813)
2.0 6.1 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) negative regulation of hyaluronan biosynthetic process(GO:1900126)
1.7 6.9 GO:0002458 peripheral T cell tolerance induction(GO:0002458) peripheral tolerance induction(GO:0002465) regulation of thymocyte migration(GO:2000410)
1.4 4.3 GO:0002501 MHC protein complex assembly(GO:0002396) peptide antigen assembly with MHC protein complex(GO:0002501)
1.4 7.0 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
1.3 4.0 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481) cytosol to ER transport(GO:0046967)
1.2 8.6 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
1.1 3.4 GO:0014805 smooth muscle adaptation(GO:0014805)
1.1 3.2 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
1.0 2.9 GO:0042262 DNA protection(GO:0042262)
0.9 9.2 GO:0032532 regulation of microvillus length(GO:0032532)
0.9 4.5 GO:0034421 post-translational protein acetylation(GO:0034421)
0.9 6.2 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.9 7.1 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.9 1.8 GO:0051385 response to mineralocorticoid(GO:0051385)
0.9 2.6 GO:1903002 regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
0.9 2.6 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.8 3.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.8 3.2 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.8 2.4 GO:1903632 positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.7 3.7 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.7 3.3 GO:0002266 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.6 8.3 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.6 2.5 GO:0019230 proprioception(GO:0019230)
0.6 1.8 GO:0036090 cleavage furrow ingression(GO:0036090)
0.6 6.7 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.6 6.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.5 0.5 GO:2000424 regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
0.5 3.6 GO:0090005 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.5 1.5 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.5 1.5 GO:0046832 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.5 4.1 GO:0032202 telomere assembly(GO:0032202)
0.5 2.0 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.5 1.9 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.5 1.0 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.5 6.6 GO:1902715 positive regulation of granulocyte macrophage colony-stimulating factor production(GO:0032725) positive regulation of interferon-gamma secretion(GO:1902715)
0.5 2.3 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.5 1.8 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.5 4.5 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.4 2.2 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.4 1.3 GO:1990164 histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164)
0.4 3.4 GO:0072718 response to cisplatin(GO:0072718)
0.4 1.2 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.4 2.9 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.4 3.9 GO:2000143 negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.4 6.4 GO:0032486 Rap protein signal transduction(GO:0032486)
0.4 2.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.3 2.8 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.3 1.4 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.3 1.4 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.3 1.0 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.3 1.6 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.3 8.9 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.3 1.6 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.3 5.6 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.3 1.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.3 2.8 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.3 0.8 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.3 0.8 GO:0034148 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) negative regulation of CD40 signaling pathway(GO:2000349)
0.3 0.8 GO:0060825 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.3 11.1 GO:0051290 protein heterotetramerization(GO:0051290)
0.3 0.8 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.3 0.8 GO:0045404 positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.3 1.8 GO:1903232 melanosome assembly(GO:1903232)
0.3 3.4 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.2 1.2 GO:1903677 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.2 0.5 GO:0051030 snRNA transport(GO:0051030)
0.2 61.1 GO:0002377 immunoglobulin production(GO:0002377)
0.2 2.3 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.2 1.3 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.2 1.9 GO:0009249 protein lipoylation(GO:0009249)
0.2 1.1 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.2 2.1 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.2 2.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.2 1.7 GO:0015675 nickel cation transport(GO:0015675)
0.2 2.9 GO:0035372 protein localization to microtubule(GO:0035372)
0.2 1.2 GO:0034627 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.2 2.0 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.2 5.5 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.2 2.5 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.2 2.6 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.2 0.5 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.2 1.3 GO:0036089 cleavage furrow formation(GO:0036089)
0.2 1.5 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 0.7 GO:1902164 positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.2 2.2 GO:0046607 positive regulation of centrosome duplication(GO:0010825) positive regulation of centrosome cycle(GO:0046607)
0.2 0.8 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.2 0.8 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882)
0.2 1.3 GO:0048318 axial mesoderm development(GO:0048318)
0.2 0.5 GO:0002355 detection of tumor cell(GO:0002355)
0.2 1.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.2 1.6 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.2 3.3 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.2 1.1 GO:0003383 apical constriction(GO:0003383)
0.1 4.6 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 2.2 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 4.5 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 8.0 GO:0031648 protein destabilization(GO:0031648)
0.1 3.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 2.4 GO:0016540 protein autoprocessing(GO:0016540)
0.1 1.1 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.1 2.5 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.1 0.9 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.1 5.8 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 1.6 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 2.4 GO:0009303 rRNA transcription(GO:0009303)
0.1 0.5 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 1.1 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.1 2.1 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.1 5.9 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 1.7 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.1 0.5 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.1 2.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 1.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 1.2 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.1 0.4 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.1 1.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 3.0 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 1.0 GO:0019985 translesion synthesis(GO:0019985)
0.1 1.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 2.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.9 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 2.1 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.1 1.3 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 0.9 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.1 0.3 GO:1903969 interleukin-4-mediated signaling pathway(GO:0035771) negative regulation of interleukin-6-mediated signaling pathway(GO:0070104) regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.1 0.6 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 4.1 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 0.3 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 0.2 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 2.4 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 0.6 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.1 4.1 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.1 0.3 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.6 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.1 0.4 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.4 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.1 0.2 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 0.5 GO:0051584 regulation of dopamine uptake involved in synaptic transmission(GO:0051584) regulation of catecholamine uptake involved in synaptic transmission(GO:0051940) positive regulation of synaptic vesicle endocytosis(GO:1900244)
0.1 0.4 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.4 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.1 0.6 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 0.4 GO:0045585 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.1 1.3 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 3.5 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.1 1.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.5 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 2.2 GO:0033198 response to ATP(GO:0033198)
0.1 0.2 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.8 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.1 5.1 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 3.9 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 2.3 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 0.6 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.1 0.1 GO:0009227 nucleotide-sugar catabolic process(GO:0009227)
0.1 0.5 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.2 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 0.8 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.1 1.5 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.1 1.0 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.1 0.9 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.1 9.3 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.1 1.4 GO:0006379 mRNA cleavage(GO:0006379)
0.1 1.4 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 2.2 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 1.7 GO:0045109 intermediate filament organization(GO:0045109)
0.1 0.2 GO:0009814 defense response, incompatible interaction(GO:0009814)
0.1 2.3 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 0.4 GO:0061366 axonogenesis involved in innervation(GO:0060385) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.3 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 1.3 GO:0097320 membrane tubulation(GO:0097320)
0.0 5.4 GO:0050868 negative regulation of T cell activation(GO:0050868)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.2 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0 0.7 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 2.7 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 1.7 GO:0031062 positive regulation of histone methylation(GO:0031062)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 1.2 GO:0035329 hippo signaling(GO:0035329)
0.0 0.5 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.6 GO:0001553 luteinization(GO:0001553)
0.0 2.7 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:0071110 protein biotinylation(GO:0009305) response to biotin(GO:0070781) histone biotinylation(GO:0071110)
0.0 0.6 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.6 GO:0097435 fibril organization(GO:0097435)
0.0 1.4 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 2.5 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 1.7 GO:0034605 cellular response to heat(GO:0034605)
0.0 1.4 GO:0048854 brain morphogenesis(GO:0048854)
0.0 0.6 GO:0070266 necroptotic process(GO:0070266)
0.0 0.3 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 1.7 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.5 GO:2000193 positive regulation of fatty acid transport(GO:2000193)
0.0 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0060431 primary lung bud formation(GO:0060431)
0.0 1.6 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.3 GO:0021559 trigeminal nerve development(GO:0021559)
0.0 2.5 GO:0051028 mRNA transport(GO:0051028)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.3 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.1 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.4 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.3 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.3 GO:1902855 nonmotile primary cilium assembly(GO:0035058) regulation of nonmotile primary cilium assembly(GO:1902855) positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.5 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.0 GO:2000407 regulation of T cell extravasation(GO:2000407) positive regulation of T cell extravasation(GO:2000409)
0.0 0.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 1.2 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.9 GO:0071482 cellular response to light stimulus(GO:0071482)
0.0 0.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 1.4 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.9 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 1.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 2.0 GO:0051607 defense response to virus(GO:0051607)
0.0 1.0 GO:0000045 autophagosome assembly(GO:0000045)
0.0 0.3 GO:0000002 mitochondrial genome maintenance(GO:0000002)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 5.9 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
1.0 5.1 GO:0034657 GID complex(GO:0034657)
0.8 3.4 GO:0071821 FANCM-MHF complex(GO:0071821)
0.8 8.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.8 4.6 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.7 3.3 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.7 2.0 GO:0000814 ESCRT II complex(GO:0000814)
0.5 2.6 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.5 2.6 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.5 4.0 GO:0042825 TAP complex(GO:0042825)
0.5 6.4 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.5 5.3 GO:0070578 micro-ribonucleoprotein complex(GO:0035068) RISC-loading complex(GO:0070578)
0.5 2.4 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.4 1.3 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.4 8.9 GO:0016600 flotillin complex(GO:0016600)
0.4 3.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.4 3.4 GO:0070545 PeBoW complex(GO:0070545)
0.4 4.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.4 10.7 GO:0000242 pericentriolar material(GO:0000242)
0.4 1.1 GO:0060473 cortical granule(GO:0060473)
0.3 1.4 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.3 0.9 GO:0034455 t-UTP complex(GO:0034455)
0.3 1.9 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.2 2.0 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.2 3.4 GO:0000812 Swr1 complex(GO:0000812)
0.2 2.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 1.5 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.2 2.8 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 3.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 1.9 GO:0031933 telomeric heterochromatin(GO:0031933)
0.2 2.3 GO:0005687 U4 snRNP(GO:0005687)
0.2 1.5 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.2 1.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.2 1.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.2 1.4 GO:0070847 core mediator complex(GO:0070847)
0.2 2.0 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.2 1.7 GO:0031595 nuclear proteasome complex(GO:0031595)
0.2 8.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.2 1.8 GO:0090571 SMN-Sm protein complex(GO:0034719) RNA polymerase II transcription repressor complex(GO:0090571)
0.2 5.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 2.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 0.4 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.1 1.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 1.1 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 0.8 GO:0070820 tertiary granule(GO:0070820)
0.1 2.1 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 0.4 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.1 1.7 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 1.4 GO:0002177 manchette(GO:0002177)
0.1 1.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 3.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 2.2 GO:0016580 Sin3 complex(GO:0016580)
0.1 2.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 1.8 GO:0005838 proteasome regulatory particle(GO:0005838)
0.1 1.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 5.6 GO:0000791 euchromatin(GO:0000791)
0.1 2.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 2.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.0 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.9 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 3.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 1.7 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 5.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 1.8 GO:0070938 contractile ring(GO:0070938)
0.1 0.4 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.1 1.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 1.1 GO:0032039 integrator complex(GO:0032039)
0.1 0.7 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.4 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 1.6 GO:0030137 COPI-coated vesicle(GO:0030137)
0.1 0.6 GO:0001940 male pronucleus(GO:0001940)
0.1 0.6 GO:0016272 prefoldin complex(GO:0016272)
0.1 2.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 3.7 GO:0005844 polysome(GO:0005844)
0.1 3.3 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 6.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 28.2 GO:0000785 chromatin(GO:0000785)
0.0 0.8 GO:0005682 U5 snRNP(GO:0005682) U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.6 GO:0071203 WASH complex(GO:0071203)
0.0 1.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.6 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 4.5 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.9 GO:0031082 BLOC complex(GO:0031082)
0.0 0.2 GO:0002142 stereocilia ankle link complex(GO:0002142)
0.0 0.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 2.5 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 4.1 GO:0005902 microvillus(GO:0005902)
0.0 1.6 GO:0032420 stereocilium(GO:0032420)
0.0 2.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 5.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 2.7 GO:0032587 ruffle membrane(GO:0032587)
0.0 2.2 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.9 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.4 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 14.1 GO:0016604 nuclear body(GO:0016604)
0.0 0.4 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 1.8 GO:0005814 centriole(GO:0005814)
0.0 32.9 GO:0005615 extracellular space(GO:0005615)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.8 GO:0000502 proteasome complex(GO:0000502)
0.0 0.9 GO:0005643 nuclear pore(GO:0005643)
0.0 1.6 GO:0000775 chromosome, centromeric region(GO:0000775)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.6 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
1.7 8.3 GO:0042610 CD8 receptor binding(GO:0042610)
1.3 4.0 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
1.0 6.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
1.0 6.7 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.9 2.6 GO:0046911 metal chelating activity(GO:0046911)
0.8 5.6 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.8 3.2 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.8 4.6 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.8 2.3 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.7 2.1 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.6 1.9 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.6 3.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.6 5.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.6 2.3 GO:0071209 U7 snRNA binding(GO:0071209)
0.5 2.2 GO:0051435 BH4 domain binding(GO:0051435)
0.5 6.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.4 8.9 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.4 1.3 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.4 1.3 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.4 4.8 GO:0019992 diacylglycerol binding(GO:0019992)
0.4 1.2 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.4 1.1 GO:0036461 BLOC-2 complex binding(GO:0036461)
0.4 3.0 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.4 2.6 GO:0048256 flap endonuclease activity(GO:0048256)
0.4 1.1 GO:0098808 mRNA cap binding(GO:0098808)
0.4 1.1 GO:0070002 glutamic-type peptidase activity(GO:0070002)
0.4 2.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.3 1.7 GO:0070287 ferritin receptor activity(GO:0070287)
0.3 1.4 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.3 1.4 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.3 1.0 GO:0047936 glucose 1-dehydrogenase [NAD(P)] activity(GO:0047936)
0.3 1.6 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.3 1.5 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.3 1.5 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.3 0.8 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.3 2.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.3 2.4 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.3 1.3 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.2 1.7 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.2 1.0 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.2 3.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.2 5.5 GO:0005132 type I interferon receptor binding(GO:0005132)
0.2 2.5 GO:0008199 ferric iron binding(GO:0008199)
0.2 2.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 1.5 GO:0043426 MRF binding(GO:0043426)
0.2 1.7 GO:0015099 nickel cation transmembrane transporter activity(GO:0015099)
0.2 2.3 GO:1990446 U1 snRNP binding(GO:1990446)
0.2 0.6 GO:0051747 cytosine C-5 DNA demethylase activity(GO:0051747)
0.2 1.2 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.2 4.7 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.2 7.6 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.2 0.9 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 8.8 GO:0003785 actin monomer binding(GO:0003785)
0.2 3.0 GO:0001727 lipid kinase activity(GO:0001727) diacylglycerol kinase activity(GO:0004143)
0.2 7.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.2 8.4 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.2 2.8 GO:0005522 profilin binding(GO:0005522)
0.2 1.8 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.2 0.5 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.2 1.9 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.2 3.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 2.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.2 1.5 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 2.2 GO:0051525 NFAT protein binding(GO:0051525)
0.1 1.0 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.1 1.4 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1 0.7 GO:0030984 kininogen binding(GO:0030984)
0.1 3.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.8 GO:0034046 poly(G) binding(GO:0034046)
0.1 7.4 GO:0045182 translation regulator activity(GO:0045182)
0.1 1.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 1.8 GO:0051378 serotonin binding(GO:0051378)
0.1 1.1 GO:0000150 recombinase activity(GO:0000150)
0.1 1.7 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 1.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 1.0 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 4.6 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 1.5 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.7 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 2.2 GO:0008143 poly(A) binding(GO:0008143)
0.1 2.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 2.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.6 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.1 1.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 5.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.4 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 3.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 5.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 1.1 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 5.9 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.1 0.4 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 1.7 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 0.3 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.1 0.4 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.1 0.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.9 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.6 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.1 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.1 5.7 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 0.4 GO:0030172 troponin C binding(GO:0030172)
0.1 3.8 GO:0003684 damaged DNA binding(GO:0003684)
0.1 2.1 GO:0070840 dynein complex binding(GO:0070840)
0.1 11.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 3.9 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.1 2.8 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.1 2.4 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 1.2 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 1.4 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 6.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 2.0 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 2.2 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.6 GO:0031996 thioesterase binding(GO:0031996)
0.0 6.8 GO:0051117 ATPase binding(GO:0051117)
0.0 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 2.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.6 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0018271 biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271)
0.0 1.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.8 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 4.1 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 1.5 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.4 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.5 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.6 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 4.6 GO:0019838 growth factor binding(GO:0019838)
0.0 0.5 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 1.5 GO:0004386 helicase activity(GO:0004386)
0.0 0.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.5 GO:0001618 virus receptor activity(GO:0001618)
0.0 11.9 GO:0003682 chromatin binding(GO:0003682)
0.0 0.2 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 1.3 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.1 GO:0044390 ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 1.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 7.3 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.4 GO:0001047 core promoter binding(GO:0001047)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 5.2 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 2.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.6 GO:0042393 histone binding(GO:0042393)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 23.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.3 4.4 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.3 4.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3 18.0 PID IFNG PATHWAY IFN-gamma pathway
0.2 19.7 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.2 1.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 3.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 9.6 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 3.4 PID MYC PATHWAY C-MYC pathway
0.1 2.3 ST GA12 PATHWAY G alpha 12 Pathway
0.1 2.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 6.4 PID E2F PATHWAY E2F transcription factor network
0.1 2.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 1.0 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.1 3.8 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 8.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 7.1 PID P73PATHWAY p73 transcription factor network
0.1 2.8 PID RHOA PATHWAY RhoA signaling pathway
0.1 0.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 2.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.4 PID P53 REGULATION PATHWAY p53 pathway
0.0 2.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 2.4 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.5 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 2.2 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.8 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 11.9 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.5 8.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.4 8.0 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.4 7.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.4 4.6 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.3 2.4 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.3 12.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.3 6.8 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.3 8.0 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 4.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.2 6.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2 4.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 6.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.2 2.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.2 5.9 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 5.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.8 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 1.4 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.1 2.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 3.3 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 2.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 6.2 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.1 2.0 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 10.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 4.7 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 7.2 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.1 1.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 4.0 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 2.7 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.1 2.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 0.4 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.1 1.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 2.0 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 4.7 REACTOME DNA REPAIR Genes involved in DNA Repair
0.1 2.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.4 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 2.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.2 REACTOME KINESINS Genes involved in Kinesins
0.0 1.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 3.2 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.4 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 2.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 3.2 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.2 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.6 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.2 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)