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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Rarb

Z-value: 0.91

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Transcription factors associated with Rarb

Gene Symbol Gene ID Gene Info
Rarb
ENSMUSG00000017491.10 Rarb

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Rarbmm39_v1_chr14_+_5894220_58942540.094.5e-01Click!

Activity profile of Rarb motif

Sorted Z-values of Rarb motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Rarb

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr12_+_8027640 15.16 ENSMUST00000171271.8
ENSMUST00000037811.13
Apob
apolipoprotein B
chr12_+_8027767 15.02 ENSMUST00000037520.14
Apob
apolipoprotein B
chr5_-_87054796 14.73 ENSMUST00000031181.16
ENSMUST00000113333.2
Ugt2b34
UDP glucuronosyltransferase 2 family, polypeptide B34
chr5_-_87288177 12.22 ENSMUST00000067790.7
Ugt2b5
UDP glucuronosyltransferase 2 family, polypeptide B5
chr6_-_85797946 9.79 ENSMUST00000032074.5
Nat8f5
N-acetyltransferase 8 (GCN5-related) family member 5
chr7_+_35148461 8.59 ENSMUST00000118969.8
Slc7a9
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
chr19_+_44980565 8.30 ENSMUST00000179305.2
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr7_+_35148579 8.29 ENSMUST00000032703.10
Slc7a9
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
chr7_+_35148188 8.27 ENSMUST00000118383.8
Slc7a9
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
chr11_+_76795346 7.36 ENSMUST00000072633.4
Tmigd1
transmembrane and immunoglobulin domain containing 1
chr11_+_76795292 6.58 ENSMUST00000142166.8
Tmigd1
transmembrane and immunoglobulin domain containing 1
chr6_-_85797917 5.72 ENSMUST00000174143.2
Nat8f6
N-acetyltransferase 8 (GCN5-related) family member 6
chr17_+_12803019 5.06 ENSMUST00000046959.9
ENSMUST00000233066.2
Slc22a2
solute carrier family 22 (organic cation transporter), member 2
chr5_-_87074380 4.10 ENSMUST00000031183.3
Ugt2b1
UDP glucuronosyltransferase 2 family, polypeptide B1
chr1_+_4878046 3.01 ENSMUST00000027036.11
ENSMUST00000150971.8
ENSMUST00000119612.9
ENSMUST00000137887.8
ENSMUST00000115529.8
Lypla1
lysophospholipase 1
chr7_-_115630282 2.68 ENSMUST00000206034.2
ENSMUST00000106612.8
Sox6
SRY (sex determining region Y)-box 6
chr5_+_93045837 2.31 ENSMUST00000113051.9
Shroom3
shroom family member 3
chr13_-_25454058 2.27 ENSMUST00000057866.13
Nrsn1
neurensin 1
chr11_-_71092282 1.47 ENSMUST00000108515.9
Nlrp1b
NLR family, pyrin domain containing 1B
chr2_+_3771709 1.14 ENSMUST00000177037.2
Fam107b
family with sequence similarity 107, member B
chr11_-_71092124 1.11 ENSMUST00000108514.10
Nlrp1b
NLR family, pyrin domain containing 1B
chr8_+_36956345 1.04 ENSMUST00000171777.2
Trmt9b
tRNA methyltransferase 9B
chr3_+_108093645 0.57 ENSMUST00000050909.7
ENSMUST00000106659.3
ENSMUST00000106656.2
Amigo1
adhesion molecule with Ig like domain 1
chr1_+_24216691 0.54 ENSMUST00000054588.15
Col9a1
collagen, type IX, alpha 1
chr10_-_81332163 0.54 ENSMUST00000020463.14
Ncln
nicalin
chr7_+_45267024 0.30 ENSMUST00000008605.6
ENSMUST00000209379.2
Fut1
fucosyltransferase 1
chr14_+_51648277 0.22 ENSMUST00000159674.4
ENSMUST00000163019.9
ENSMUST00000233394.2
ENSMUST00000232951.2
ENSMUST00000232797.2
ENSMUST00000233766.2
ENSMUST00000233848.2
ENSMUST00000233280.2
ENSMUST00000233920.2
ENSMUST00000233126.2
ENSMUST00000233651.2
Vmn2r88
vomeronasal 2, receptor 88
chr16_+_38167352 0.18 ENSMUST00000050273.9
ENSMUST00000120495.2
ENSMUST00000119704.2
Cox17
Gm21987
cytochrome c oxidase assembly protein 17, copper chaperone
predicted gene 21987
chr3_-_52012462 0.06 ENSMUST00000121440.4
Maml3
mastermind like transcriptional coactivator 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.3 25.1 GO:0015811 L-cystine transport(GO:0015811)
2.2 30.2 GO:0006642 triglyceride mobilization(GO:0006642)
1.4 4.1 GO:0018879 biphenyl metabolic process(GO:0018879)
0.6 2.6 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.5 3.0 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.3 5.1 GO:0051608 quaternary ammonium group transport(GO:0015697) histamine transport(GO:0051608)
0.2 2.7 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.2 9.8 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.1 8.3 GO:0050919 negative chemotaxis(GO:0050919)
0.1 0.2 GO:1904959 regulation of cytochrome-c oxidase activity(GO:1904959)
0.0 0.6 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.5 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 2.3 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 0.3 GO:0036065 fucosylation(GO:0036065)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
10.1 30.2 GO:0034359 mature chylomicron(GO:0034359)
0.4 2.6 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.2 25.1 GO:0031526 brush border membrane(GO:0031526)
0.1 0.5 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 12.2 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 5.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.6 GO:0032809 neuronal cell body membrane(GO:0032809)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.3 25.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
2.3 30.2 GO:0035473 lipase binding(GO:0035473)
1.7 5.1 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) norepinephrine transmembrane transporter activity(GO:0005333) acetate ester transmembrane transporter activity(GO:1901375)
0.8 31.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.3 3.0 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.3 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1 6.9 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.2 GO:0016531 copper chaperone activity(GO:0016531)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 30.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 8.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 30.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.5 25.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.4 5.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 1.3 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation