ISMARA results: Rela_Rel

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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Rela_Rel_Nfkb1

Z-value: 2.88

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Transcription factors associated with Rela_Rel_Nfkb1

Gene Symbol	Gene ID	Gene Info
Rela Ensembl NCBI MGI UniProt	ENSMUSG00000024927.9	Rela
Rel Ensembl NCBI MGI UniProt	ENSMUSG00000020275.10	Rel
Nfkb1 Ensembl NCBI MGI UniProt	ENSMUSG00000028163.18	Nfkb1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Nfkb1	mm39_v1_chr3_-_135397298_135397309	0.83	2.6e-19	Click!
Rel	mm39_v1_chr11_-_23720953_23721028	0.62	6.9e-09	Click!
Rela	mm39_v1_chr19_+_5687503_5687514	0.45	8.2e-05	Click!

Activity profile of Rela_Rel_Nfkb1 motif

Sorted Z-values of Rela_Rel_Nfkb1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Rela_Rel_Nfkb1

View svg image
View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr18_+_60936910 Show fit	48.92	ENSMUST00000097563.9 ENSMUST00000050487.16 ENSMUST00000167610.2	Cd74 Ensembl NCBI MGI UniProt Show fit	CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
chr6_-_129252396 Show fit	37.67	ENSMUST00000032259.6	Cd69 Ensembl NCBI MGI UniProt Show fit	CD69 antigen
chr17_+_37504783 Show fit	37.55	ENSMUST00000038844.7	Ubd Ensembl NCBI MGI UniProt Show fit	ubiquitin D
chr17_+_35658131 Show fit	33.14	ENSMUST00000071951.14 ENSMUST00000116598.10 ENSMUST00000078205.14 ENSMUST00000076256.8	H2-Q7 Ensembl NCBI MGI UniProt Show fit	histocompatibility 2, Q region locus 7
chr17_+_35413415 Show fit	29.78	ENSMUST00000025262.6 ENSMUST00000173600.2	Ltb Ensembl NCBI MGI UniProt Show fit	lymphotoxin B
chr19_+_46293210 Show fit	27.87	ENSMUST00000236591.2	Nfkb2 Ensembl NCBI MGI UniProt Show fit	nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr9_-_7873017 Show fit	25.99	ENSMUST00000013949.15	Birc3 Ensembl NCBI MGI UniProt Show fit	baculoviral IAP repeat-containing 3
chr11_-_83421333 Show fit	24.71	ENSMUST00000035938.3	Ccl5 Ensembl NCBI MGI UniProt Show fit	chemokine (C-C motif) ligand 5
chr9_-_7873171 Show fit	24.58	ENSMUST00000159323.2 ENSMUST00000115673.3	Birc3 Ensembl NCBI MGI UniProt Show fit	baculoviral IAP repeat-containing 3
chr10_-_18891095 Show fit	24.25	ENSMUST00000019997.11	Tnfaip3 Ensembl NCBI MGI UniProt Show fit	tumor necrosis factor, alpha-induced protein 3
chr19_+_46293160 Show fit	24.17	ENSMUST00000073116.13	Nfkb2 Ensembl NCBI MGI UniProt Show fit	nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr7_-_19363280 Show fit	24.00	ENSMUST00000094762.10 ENSMUST00000049912.15 ENSMUST00000098754.5	Relb Ensembl NCBI MGI UniProt Show fit	avian reticuloendotheliosis viral (v-rel) oncogene related B
chr10_+_79500387 Show fit	23.14	ENSMUST00000020554.8	Madcam1 Ensembl NCBI MGI UniProt Show fit	mucosal vascular addressin cell adhesion molecule 1
chr6_-_129252323 Show fit	20.95	ENSMUST00000204411.2	Cd69 Ensembl NCBI MGI UniProt Show fit	CD69 antigen
chr17_+_31427023 Show fit	20.91	ENSMUST00000173776.2 ENSMUST00000048656.15	Ubash3a Ensembl NCBI MGI UniProt Show fit	ubiquitin associated and SH3 domain containing, A
chr17_-_34506744 Show fit	20.12	ENSMUST00000174751.2 ENSMUST00000040655.14	H2-Aa Ensembl NCBI MGI UniProt Show fit	histocompatibility 2, class II antigen A, alpha
chr10_+_79500421 Show fit	19.48	ENSMUST00000217748.2	Madcam1 Ensembl NCBI MGI UniProt Show fit	mucosal vascular addressin cell adhesion molecule 1
chr9_-_7872970 Show fit	19.25	ENSMUST00000115672.2	Birc3 Ensembl NCBI MGI UniProt Show fit	baculoviral IAP repeat-containing 3
chr12_+_85733415 Show fit	19.00	ENSMUST00000040536.6	Batf Ensembl NCBI MGI UniProt Show fit	basic leucine zipper transcription factor, ATF-like
chr1_+_172327569 Show fit	18.86	ENSMUST00000111230.8	Tagln2 Ensembl NCBI MGI UniProt Show fit	transgelin 2
chr1_+_172327812 Show fit	18.85	ENSMUST00000192460.2	Tagln2 Ensembl NCBI MGI UniProt Show fit	transgelin 2
chr12_-_55539372 Show fit	18.79	ENSMUST00000021413.9	Nfkbia Ensembl NCBI MGI UniProt Show fit	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
chr12_+_111383864 Show fit	18.08	ENSMUST00000220537.2 ENSMUST00000223050.2 ENSMUST00000072646.8 ENSMUST00000223431.2 ENSMUST00000221144.2 ENSMUST00000222437.2	Exoc3l4 Ensembl NCBI MGI UniProt Show fit	exocyst complex component 3-like 4
chr16_-_55659194 Show fit	17.87	ENSMUST00000096026.9 ENSMUST00000036273.13 ENSMUST00000114457.8	Nfkbiz Ensembl NCBI MGI UniProt Show fit	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
chr5_-_92496730 Show fit	17.25	ENSMUST00000038816.13 ENSMUST00000118006.3	Cxcl10 Ensembl NCBI MGI UniProt Show fit	chemokine (C-X-C motif) ligand 10
chr9_-_44437694 Show fit	16.04	ENSMUST00000062215.8	Cxcr5 Ensembl NCBI MGI UniProt Show fit	chemokine (C-X-C motif) receptor 5
chr14_-_55828511 Show fit	16.00	ENSMUST00000161807.8 ENSMUST00000111378.10 ENSMUST00000159687.2	Psme2 Ensembl NCBI MGI UniProt Show fit	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr1_-_135186176 Show fit	15.86	ENSMUST00000185752.2 ENSMUST00000003135.14	Elf3 Ensembl NCBI MGI UniProt Show fit	E74-like factor 3
chr1_-_172418058 Show fit	15.80	ENSMUST00000065679.8	Slamf8 Ensembl NCBI MGI UniProt Show fit	SLAM family member 8
chr11_+_100751272 Show fit	15.30	ENSMUST00000107357.4	Stat5a Ensembl NCBI MGI UniProt Show fit	signal transducer and activator of transcription 5A
chr11_+_100751151 Show fit	15.03	ENSMUST00000138083.8	Stat5a Ensembl NCBI MGI UniProt Show fit	signal transducer and activator of transcription 5A
chr1_+_192984278 Show fit	14.49	ENSMUST00000016315.16	Lamb3 Ensembl NCBI MGI UniProt Show fit	laminin, beta 3
chrX_-_73289970 Show fit	14.30	ENSMUST00000130007.8	Flna Ensembl NCBI MGI UniProt Show fit	filamin, alpha
chr7_+_30121776 Show fit	14.19	ENSMUST00000108175.8	Nfkbid Ensembl NCBI MGI UniProt Show fit	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
chr10_-_12839995 Show fit	14.18	ENSMUST00000219727.2 ENSMUST00000163425.9 ENSMUST00000042861.7 ENSMUST00000218685.2	Stx11 Ensembl NCBI MGI UniProt Show fit	syntaxin 11
chr19_+_46294119 Show fit	13.99	ENSMUST00000111881.4	Nfkb2 Ensembl NCBI MGI UniProt Show fit	nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr5_+_136996713 Show fit	13.97	ENSMUST00000001790.6	Cldn15 Ensembl NCBI MGI UniProt Show fit	claudin 15
chr3_-_83749036 Show fit	13.74	ENSMUST00000029623.11	Tlr2 Ensembl NCBI MGI UniProt Show fit	toll-like receptor 2
chrX_-_73290140 Show fit	13.71	ENSMUST00000101454.9 ENSMUST00000033699.13	Flna Ensembl NCBI MGI UniProt Show fit	filamin, alpha
chr17_-_35424281 Show fit	13.53	ENSMUST00000025266.6	Lta Ensembl NCBI MGI UniProt Show fit	lymphotoxin A
chr5_+_43976218 Show fit	13.42	ENSMUST00000101237.8	Bst1 Ensembl NCBI MGI UniProt Show fit	bone marrow stromal cell antigen 1
chr17_+_35598583 Show fit	13.20	ENSMUST00000081435.5	H2-Q4 Ensembl NCBI MGI UniProt Show fit	histocompatibility 2, Q region locus 4
chr12_-_114117264 Show fit	13.20	ENSMUST00000103461.5	Ighv7-3 Ensembl NCBI MGI UniProt Show fit	immunoglobulin heavy variable 7-3
chr3_-_135397298 Show fit	12.87	ENSMUST00000029812.14	Nfkb1 Ensembl NCBI MGI UniProt Show fit	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
chrX_+_7523499 Show fit	12.64	ENSMUST00000033485.14	Prickle3 Ensembl NCBI MGI UniProt Show fit	prickle planar cell polarity protein 3
chr11_+_69471185 Show fit	12.61	ENSMUST00000171247.8 ENSMUST00000108658.10 ENSMUST00000005371.12	Trp53 Ensembl NCBI MGI UniProt Show fit	transformation related protein 53
chr9_+_32607301 Show fit	12.58	ENSMUST00000034534.13 ENSMUST00000050797.14 ENSMUST00000184887.2	Ets1 Ensembl NCBI MGI UniProt Show fit	E26 avian leukemia oncogene 1, 5' domain
chr9_+_5308828 Show fit	12.45	ENSMUST00000162846.8 ENSMUST00000027012.14	Casp4 Ensembl NCBI MGI UniProt Show fit	caspase 4, apoptosis-related cysteine peptidase
chr11_+_100750316 Show fit	12.35	ENSMUST00000107356.8	Stat5a Ensembl NCBI MGI UniProt Show fit	signal transducer and activator of transcription 5A
chr18_-_4352944 Show fit	11.99	ENSMUST00000025078.10	Map3k8 Ensembl NCBI MGI UniProt Show fit	mitogen-activated protein kinase kinase kinase 8
chr11_+_69471219 Show fit	11.89	ENSMUST00000108657.4	Trp53 Ensembl NCBI MGI UniProt Show fit	transformation related protein 53
chr12_+_79177523 Show fit	11.79	ENSMUST00000021550.7	Arg2 Ensembl NCBI MGI UniProt Show fit	arginase type II
chr7_-_126613707 Show fit	11.37	ENSMUST00000165096.9	Mvp Ensembl NCBI MGI UniProt Show fit	major vault protein
chr6_-_69792108 Show fit	11.31	ENSMUST00000103367.3	Igkv12-44 Ensembl NCBI MGI UniProt Show fit	immunoglobulin kappa variable 12-44
chr6_+_68233361 Show fit	11.31	ENSMUST00000103320.3	Igkv14-111 Ensembl NCBI MGI UniProt Show fit	immunoglobulin kappa variable 14-111
chr17_-_23964807 Show fit	11.22	ENSMUST00000046525.10	Kremen2 Ensembl NCBI MGI UniProt Show fit	kringle containing transmembrane protein 2
chr18_+_4994600 Show fit	10.94	ENSMUST00000140448.8	Svil Ensembl NCBI MGI UniProt Show fit	supervillin
chr14_-_30329765 Show fit	10.65	ENSMUST00000112207.8 ENSMUST00000112206.8 ENSMUST00000112202.8 ENSMUST00000112203.2	Prkcd Ensembl NCBI MGI UniProt Show fit	protein kinase C, delta
chr3_-_65865656 Show fit	10.61	ENSMUST00000029416.14	Ccnl1 Ensembl NCBI MGI UniProt Show fit	cyclin L1
chr8_-_62355690 Show fit	10.61	ENSMUST00000121785.9 ENSMUST00000034057.14	Palld Ensembl NCBI MGI UniProt Show fit	palladin, cytoskeletal associated protein
chr11_-_54853729 Show fit	10.43	ENSMUST00000108885.8 ENSMUST00000102730.9 ENSMUST00000018482.13 ENSMUST00000108886.8 ENSMUST00000102731.8	Tnip1 Ensembl NCBI MGI UniProt Show fit	TNFAIP3 interacting protein 1
chr17_-_37794434 Show fit	10.42	ENSMUST00000016427.11 ENSMUST00000171139.3	H2-M2 Ensembl NCBI MGI UniProt Show fit	histocompatibility 2, M region locus 2
chr8_-_25591737 Show fit	10.33	ENSMUST00000098866.11	Plekha2 Ensembl NCBI MGI UniProt Show fit	pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr6_+_67873135 Show fit	10.28	ENSMUST00000103310.3	Igkv14-126 Ensembl NCBI MGI UniProt Show fit	immunoglobulin kappa variable 14-126
chr1_+_130728639 Show fit	10.24	ENSMUST00000112477.9 ENSMUST00000027670.4	Fcamr Ensembl NCBI MGI UniProt Show fit	Fc receptor, IgA, IgM, high affinity
chr7_+_30121147 Show fit	10.22	ENSMUST00000108176.9	Nfkbid Ensembl NCBI MGI UniProt Show fit	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
chr2_-_32277773 Show fit	10.14	ENSMUST00000050785.14	Lcn2 Ensembl NCBI MGI UniProt Show fit	lipocalin 2
chr8_-_105357941 Show fit	10.10	ENSMUST00000034351.8	Rrad Ensembl NCBI MGI UniProt Show fit	Ras-related associated with diabetes
chr1_+_135060994 Show fit	10.06	ENSMUST00000167080.3	Ptpn7 Ensembl NCBI MGI UniProt Show fit	protein tyrosine phosphatase, non-receptor type 7
chr6_-_68812291 Show fit	10.03	ENSMUST00000199143.5 ENSMUST00000103335.3	Igkv12-89 Ensembl NCBI MGI UniProt Show fit	immunoglobulin kappa chain variable 12-89
chr8_-_25592001 Show fit	9.96	ENSMUST00000128715.8	Plekha2 Ensembl NCBI MGI UniProt Show fit	pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr7_+_75105282 Show fit	9.93	ENSMUST00000207750.2 ENSMUST00000166315.7	Akap13 Ensembl NCBI MGI UniProt Show fit	A kinase (PRKA) anchor protein 13
chr9_-_44920899 Show fit	9.80	ENSMUST00000102832.3	Cd3e Ensembl NCBI MGI UniProt Show fit	CD3 antigen, epsilon polypeptide
chr9_-_44437801 Show fit	9.74	ENSMUST00000215661.2	Cxcr5 Ensembl NCBI MGI UniProt Show fit	chemokine (C-X-C motif) receptor 5
chr3_+_14706781 Show fit	9.51	ENSMUST00000029071.9	Car13 Ensembl NCBI MGI UniProt Show fit	carbonic anhydrase 13
chr1_+_132996237 Show fit	9.41	ENSMUST00000239467.2	Pik3c2b Ensembl NCBI MGI UniProt Show fit	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
chr1_+_64571942 Show fit	9.35	ENSMUST00000171164.8 ENSMUST00000187811.7 ENSMUST00000049932.12 ENSMUST00000087366.11	Creb1 Ensembl NCBI MGI UniProt Show fit	cAMP responsive element binding protein 1
chr1_+_64571768 Show fit	9.34	ENSMUST00000185594.7	Creb1 Ensembl NCBI MGI UniProt Show fit	cAMP responsive element binding protein 1
chr7_-_44180700 Show fit	9.30	ENSMUST00000205506.2	Spib Ensembl NCBI MGI UniProt Show fit	Spi-B transcription factor (Spi-1/PU.1 related)
chr1_-_36312482 Show fit	9.24	ENSMUST00000056946.8	Neurl3 Ensembl NCBI MGI UniProt Show fit	neuralized E3 ubiquitin protein ligase 3
chr8_-_25592385 Show fit	9.22	ENSMUST00000064883.14	Plekha2 Ensembl NCBI MGI UniProt Show fit	pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr17_+_35643818 Show fit	9.14	ENSMUST00000174699.8	H2-Q6 Ensembl NCBI MGI UniProt Show fit	histocompatibility 2, Q region locus 6
chr7_-_25488060 Show fit	9.11	ENSMUST00000002677.11 ENSMUST00000085948.11	Axl Ensembl NCBI MGI UniProt Show fit	AXL receptor tyrosine kinase
chr6_-_69835868 Show fit	9.11	ENSMUST00000103369.2	Igkv12-41 Ensembl NCBI MGI UniProt Show fit	immunoglobulin kappa chain variable 12-41
chr17_+_35643853 Show fit	9.06	ENSMUST00000113879.4	H2-Q6 Ensembl NCBI MGI UniProt Show fit	histocompatibility 2, Q region locus 6
chr10_-_79940168 Show fit	9.04	ENSMUST00000219260.2	Sbno2 Ensembl NCBI MGI UniProt Show fit	strawberry notch 2
chr12_-_84240781 Show fit	9.02	ENSMUST00000110294.2	Mideas Ensembl NCBI MGI UniProt Show fit	mitotic deacetylase associated SANT domain protein
chr11_-_54846873 Show fit	8.99	ENSMUST00000155316.2 ENSMUST00000108889.10 ENSMUST00000126703.8	Tnip1 Ensembl NCBI MGI UniProt Show fit	TNFAIP3 interacting protein 1
chr11_+_117700479 Show fit	8.79	ENSMUST00000026649.14 ENSMUST00000177131.8 ENSMUST00000120928.2 ENSMUST00000175737.2 ENSMUST00000132298.2	Syngr2 Ensembl NCBI MGI UniProt Show fit Gm20708 Ensembl NCBI MGI UniProt Show fit	synaptogyrin 2 predicted gene 20708
chr18_-_35855383 Show fit	8.58	ENSMUST00000133064.8	Ecscr Ensembl NCBI MGI UniProt Show fit	endothelial cell surface expressed chemotaxis and apoptosis regulator
chr12_-_115471634 Show fit	8.47	ENSMUST00000103535.3	Ighv1-64 Ensembl NCBI MGI UniProt Show fit	immunoglobulin heavy variable 1-64
chr5_-_105287405 Show fit	8.31	ENSMUST00000100961.5 ENSMUST00000031235.13 ENSMUST00000197799.2 ENSMUST00000199629.2 ENSMUST00000196677.5 ENSMUST00000100962.8	Gbp9 Ensembl NCBI MGI UniProt Show fit Gbp8 Ensembl NCBI MGI UniProt Show fit Gbp4 Ensembl NCBI MGI UniProt Show fit	guanylate-binding protein 9 guanylate-binding protein 8 guanylate binding protein 4
chr6_+_48818410 Show fit	8.23	ENSMUST00000101426.11 ENSMUST00000168406.4	Tmem176a Ensembl NCBI MGI UniProt Show fit	transmembrane protein 176A
chr11_-_23720953 Show fit	8.20	ENSMUST00000102864.5	Rel Ensembl NCBI MGI UniProt Show fit	reticuloendotheliosis oncogene
chr8_-_89362745 Show fit	8.19	ENSMUST00000034087.9	Snx20 Ensembl NCBI MGI UniProt Show fit	sorting nexin 20
chr5_-_105441554 Show fit	8.06	ENSMUST00000050011.10 ENSMUST00000196520.2	Gm43302 Ensembl NCBI MGI UniProt Show fit Gbp6 Ensembl NCBI MGI UniProt Show fit	predicted gene 43302 guanylate binding protein 6
chr1_-_134006847 Show fit	7.79	ENSMUST00000020692.7	Btg2 Ensembl NCBI MGI UniProt Show fit	BTG anti-proliferation factor 2
chr14_+_54457978 Show fit	7.78	ENSMUST00000103740.2 ENSMUST00000198398.5	Trac Ensembl NCBI MGI UniProt Show fit	T cell receptor alpha constant
chr7_+_24069680 Show fit	7.78	ENSMUST00000205428.2 ENSMUST00000171904.3 ENSMUST00000205626.2	Kcnn4 Ensembl NCBI MGI UniProt Show fit	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr1_+_64572050 Show fit	7.77	ENSMUST00000190348.2	Creb1 Ensembl NCBI MGI UniProt Show fit	cAMP responsive element binding protein 1
chr14_+_80237691 Show fit	7.75	ENSMUST00000228749.2 ENSMUST00000088735.4	Olfm4 Ensembl NCBI MGI UniProt Show fit	olfactomedin 4
chr8_+_47192911 Show fit	7.62	ENSMUST00000208433.2	Irf2 Ensembl NCBI MGI UniProt Show fit	interferon regulatory factor 2
chr4_+_129713991 Show fit	7.62	ENSMUST00000030578.14	Ptp4a2 Ensembl NCBI MGI UniProt Show fit	protein tyrosine phosphatase 4a2
chr14_-_54655079 Show fit	7.57	ENSMUST00000226753.2 ENSMUST00000197440.5	Slc7a7 Ensembl NCBI MGI UniProt Show fit	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr6_-_48817914 Show fit	7.50	ENSMUST00000164733.4	Tmem176b Ensembl NCBI MGI UniProt Show fit	transmembrane protein 176B
chr6_+_41090484 Show fit	7.50	ENSMUST00000103267.3	Trbv12-1 Ensembl NCBI MGI UniProt Show fit	T cell receptor beta, variable 12-1
chr1_+_159871943 Show fit	7.43	ENSMUST00000163892.8	4930523C07Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 4930523C07 gene
chr8_-_105357872 Show fit	7.42	ENSMUST00000212163.2	Rrad Ensembl NCBI MGI UniProt Show fit	Ras-related associated with diabetes
chr12_-_113823290 Show fit	7.42	ENSMUST00000103459.5	Ighv5-17 Ensembl NCBI MGI UniProt Show fit	immunoglobulin heavy variable 5-17
chr12_+_111409087 Show fit	7.35	ENSMUST00000109792.8	Tnfaip2 Ensembl NCBI MGI UniProt Show fit	tumor necrosis factor, alpha-induced protein 2
chr17_+_56259617 Show fit	7.32	ENSMUST00000003274.8	Ebi3 Ensembl NCBI MGI UniProt Show fit	Epstein-Barr virus induced gene 3
chr7_-_126651847 Show fit	7.28	ENSMUST00000205424.2	Zg16 Ensembl NCBI MGI UniProt Show fit	zymogen granule protein 16
chr15_-_76501525 Show fit	7.24	ENSMUST00000230977.2	Slc39a4 Ensembl NCBI MGI UniProt Show fit	solute carrier family 39 (zinc transporter), member 4
chr11_-_69771797 Show fit	7.23	ENSMUST00000238978.2	Kctd11 Ensembl NCBI MGI UniProt Show fit	potassium channel tetramerisation domain containing 11
chr4_+_130643260 Show fit	7.23	ENSMUST00000030316.7	Laptm5 Ensembl NCBI MGI UniProt Show fit	lysosomal-associated protein transmembrane 5
chr11_-_99045894 Show fit	7.13	ENSMUST00000103134.4	Ccr7 Ensembl NCBI MGI UniProt Show fit	chemokine (C-C motif) receptor 7
chr6_-_78445846 Show fit	7.12	ENSMUST00000032089.3	Reg3g Ensembl NCBI MGI UniProt Show fit	regenerating islet-derived 3 gamma
chr9_-_31043076 Show fit	7.12	ENSMUST00000034478.3	St14 Ensembl NCBI MGI UniProt Show fit	suppression of tumorigenicity 14 (colon carcinoma)
chr2_-_118377500 Show fit	7.09	ENSMUST00000125860.3	Bmf Ensembl NCBI MGI UniProt Show fit	BCL2 modifying factor
chr9_+_123596276 Show fit	7.06	ENSMUST00000166236.9 ENSMUST00000111454.4 ENSMUST00000168910.2	Ccr9 Ensembl NCBI MGI UniProt Show fit	chemokine (C-C motif) receptor 9
chr6_-_48818302 Show fit	7.03	ENSMUST00000203355.3 ENSMUST00000166247.8	Tmem176b Ensembl NCBI MGI UniProt Show fit	transmembrane protein 176B
chr11_-_70213348 Show fit	7.01	ENSMUST00000019051.3	Alox12e Ensembl NCBI MGI UniProt Show fit	arachidonate lipoxygenase, epidermal
chr13_+_43938251 Show fit	6.98	ENSMUST00000015540.4	Cd83 Ensembl NCBI MGI UniProt Show fit	CD83 antigen
chr3_+_142202642 Show fit	6.97	ENSMUST00000090127.7	Gbp5 Ensembl NCBI MGI UniProt Show fit	guanylate binding protein 5
chr11_-_83469446 Show fit	6.92	ENSMUST00000019266.6	Ccl9 Ensembl NCBI MGI UniProt Show fit	chemokine (C-C motif) ligand 9
chr11_+_120333470 Show fit	6.89	ENSMUST00000044105.9	Tspan10 Ensembl NCBI MGI UniProt Show fit	tetraspanin 10
chr6_-_48818006 Show fit	6.86	ENSMUST00000203229.3	Tmem176b Ensembl NCBI MGI UniProt Show fit	transmembrane protein 176B
chr4_+_151012375 Show fit	6.78	ENSMUST00000139826.8 ENSMUST00000116257.8	Tnfrsf9 Ensembl NCBI MGI UniProt Show fit	tumor necrosis factor receptor superfamily, member 9
chr6_+_41098273 Show fit	6.55	ENSMUST00000103270.4	Trbv13-2 Ensembl NCBI MGI UniProt Show fit	T cell receptor beta, variable 13-2
chr15_+_79779218 Show fit	6.53	ENSMUST00000023054.14	Apobec3 Ensembl NCBI MGI UniProt Show fit	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3
chr15_+_80456775 Show fit	6.48	ENSMUST00000229980.2	Grap2 Ensembl NCBI MGI UniProt Show fit	GRB2-related adaptor protein 2
chr6_-_48818430 Show fit	6.39	ENSMUST00000205147.3	Tmem176b Ensembl NCBI MGI UniProt Show fit	transmembrane protein 176B
chr17_-_84495364 Show fit	6.37	ENSMUST00000060366.7	Zfp36l2 Ensembl NCBI MGI UniProt Show fit	zinc finger protein 36, C3H type-like 2
chr2_-_32278245 Show fit	6.36	ENSMUST00000192241.2	Lcn2 Ensembl NCBI MGI UniProt Show fit	lipocalin 2
chr4_-_101122433 Show fit	6.34	ENSMUST00000149297.2 ENSMUST00000102781.10	Jak1 Ensembl NCBI MGI UniProt Show fit	Janus kinase 1
chr4_-_125021610 Show fit	6.27	ENSMUST00000036188.8	Zc3h12a Ensembl NCBI MGI UniProt Show fit	zinc finger CCCH type containing 12A
chr1_+_192835414 Show fit	6.25	ENSMUST00000076521.7	Irf6 Ensembl NCBI MGI UniProt Show fit	interferon regulatory factor 6
chr18_-_20192535 Show fit	6.19	ENSMUST00000075214.9 ENSMUST00000039247.11	Dsc2 Ensembl NCBI MGI UniProt Show fit	desmocollin 2
chr7_+_16043502 Show fit	6.16	ENSMUST00000002152.13	Bbc3 Ensembl NCBI MGI UniProt Show fit	BCL2 binding component 3
chr8_-_123159663 Show fit	6.15	ENSMUST00000017604.10	Cyba Ensembl NCBI MGI UniProt Show fit	cytochrome b-245, alpha polypeptide
chr6_-_48818044 Show fit	6.10	ENSMUST00000101429.11 ENSMUST00000204073.3	Tmem176b Ensembl NCBI MGI UniProt Show fit	transmembrane protein 176B
chr1_+_83094481 Show fit	6.08	ENSMUST00000027351.13 ENSMUST00000113437.9 ENSMUST00000186832.2	Ccl20 Ensembl NCBI MGI UniProt Show fit	chemokine (C-C motif) ligand 20
chr11_-_48884999 Show fit	5.98	ENSMUST00000146439.8	Tgtp1 Ensembl NCBI MGI UniProt Show fit	T cell specific GTPase 1
chr10_+_80765900 Show fit	5.96	ENSMUST00000015456.10 ENSMUST00000220246.2	Gadd45b Ensembl NCBI MGI UniProt Show fit	growth arrest and DNA-damage-inducible 45 beta
chr5_-_92475927 Show fit	5.90	ENSMUST00000113093.5	Cxcl9 Ensembl NCBI MGI UniProt Show fit	chemokine (C-X-C motif) ligand 9
chr19_+_34268053 Show fit	5.89	ENSMUST00000025691.13	Fas Ensembl NCBI MGI UniProt Show fit	Fas (TNF receptor superfamily member 6)
chr11_+_83007635 Show fit	5.87	ENSMUST00000037994.8	Slfn1 Ensembl NCBI MGI UniProt Show fit	schlafen 1
chr2_-_103133503 Show fit	5.86	ENSMUST00000111176.9	Ehf Ensembl NCBI MGI UniProt Show fit	ets homologous factor
chr19_+_34268071 Show fit	5.85	ENSMUST00000112472.4 ENSMUST00000235232.2	Fas Ensembl NCBI MGI UniProt Show fit	Fas (TNF receptor superfamily member 6)
chr5_-_18040713 Show fit	5.84	ENSMUST00000197890.5	Cd36 Ensembl NCBI MGI UniProt Show fit	CD36 molecule
chr12_-_80307110 Show fit	5.82	ENSMUST00000021554.16	Actn1 Ensembl NCBI MGI UniProt Show fit	actinin, alpha 1
chr17_-_34219225 Show fit	5.77	ENSMUST00000238098.2 ENSMUST00000087189.7 ENSMUST00000173075.3 ENSMUST00000172912.8 ENSMUST00000236740.2 ENSMUST00000025181.18	H2-K1 Ensembl NCBI MGI UniProt Show fit	histocompatibility 2, K1, K region
chr17_+_35482063 Show fit	5.75	ENSMUST00000172503.3	H2-D1 Ensembl NCBI MGI UniProt Show fit	histocompatibility 2, D region locus 1
chr1_-_173707677 Show fit	5.74	ENSMUST00000190651.4 ENSMUST00000188804.7	Mndal Ensembl NCBI MGI UniProt Show fit	myeloid nuclear differentiation antigen like
chrX_-_74174450 Show fit	5.72	ENSMUST00000114092.8 ENSMUST00000132501.8 ENSMUST00000153318.8 ENSMUST00000155742.2	Mpp1 Ensembl NCBI MGI UniProt Show fit	membrane protein, palmitoylated
chr17_+_35481702 Show fit	5.72	ENSMUST00000172785.8	H2-D1 Ensembl NCBI MGI UniProt Show fit	histocompatibility 2, D region locus 1
chr17_+_37209002 Show fit	5.71	ENSMUST00000078438.5	Trim31 Ensembl NCBI MGI UniProt Show fit	tripartite motif-containing 31
chr13_+_42205491 Show fit	5.68	ENSMUST00000060148.6	Hivep1 Ensembl NCBI MGI UniProt Show fit	human immunodeficiency virus type I enhancer binding protein 1
chr5_-_18040647 Show fit	5.60	ENSMUST00000082367.13	Cd36 Ensembl NCBI MGI UniProt Show fit	CD36 molecule
chr14_+_56122404 Show fit	5.57	ENSMUST00000022831.5	Khnyn Ensembl NCBI MGI UniProt Show fit	KH and NYN domain containing
chr2_+_13578738 Show fit	5.54	ENSMUST00000141365.3 ENSMUST00000028062.8	Vim Ensembl NCBI MGI UniProt Show fit	vimentin
chr10_+_58230203 Show fit	5.53	ENSMUST00000105468.2	Lims1 Ensembl NCBI MGI UniProt Show fit	LIM and senescent cell antigen-like domains 1
chr17_+_34406523 Show fit	5.50	ENSMUST00000170086.8	Tap1 Ensembl NCBI MGI UniProt Show fit	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr8_-_123159639 Show fit	5.50	ENSMUST00000212600.2	Cyba Ensembl NCBI MGI UniProt Show fit	cytochrome b-245, alpha polypeptide
chr11_+_48977852 Show fit	5.43	ENSMUST00000046704.7 ENSMUST00000203810.3 ENSMUST00000203149.3	Ifi47 Ensembl NCBI MGI UniProt Show fit Olfr56 Ensembl NCBI MGI UniProt Show fit	interferon gamma inducible protein 47 olfactory receptor 56
chr9_+_69361348 Show fit	5.43	ENSMUST00000134907.8	Anxa2 Ensembl NCBI MGI UniProt Show fit	annexin A2
chr4_+_43957677 Show fit	5.39	ENSMUST00000107855.2	Glipr2 Ensembl NCBI MGI UniProt Show fit	GLI pathogenesis-related 2
chr17_+_45997248 Show fit	5.37	ENSMUST00000024734.8	Mrpl14 Ensembl NCBI MGI UniProt Show fit	mitochondrial ribosomal protein L14
chr2_-_60711706 Show fit	5.33	ENSMUST00000164147.8 ENSMUST00000112509.2	Rbms1 Ensembl NCBI MGI UniProt Show fit	RNA binding motif, single stranded interacting protein 1
chr4_+_43957401 Show fit	5.28	ENSMUST00000030202.14	Glipr2 Ensembl NCBI MGI UniProt Show fit	GLI pathogenesis-related 2
chrX_-_74174608 Show fit	5.27	ENSMUST00000033775.9	Mpp1 Ensembl NCBI MGI UniProt Show fit	membrane protein, palmitoylated
chr1_+_135060431 Show fit	5.25	ENSMUST00000187985.7 ENSMUST00000049449.11	Ptpn7 Ensembl NCBI MGI UniProt Show fit	protein tyrosine phosphatase, non-receptor type 7
chr3_+_127584251 Show fit	5.25	ENSMUST00000164447.3	Tifa Ensembl NCBI MGI UniProt Show fit	TRAF-interacting protein with forkhead-associated domain
chr14_-_30348153 Show fit	5.23	ENSMUST00000112211.9 ENSMUST00000112210.11	Prkcd Ensembl NCBI MGI UniProt Show fit	protein kinase C, delta
chrX_+_41591476 Show fit	5.22	ENSMUST00000115070.8 ENSMUST00000153948.2	Sh2d1a Ensembl NCBI MGI UniProt Show fit	SH2 domain containing 1A
chr2_-_103133524 Show fit	5.20	ENSMUST00000090475.10	Ehf Ensembl NCBI MGI UniProt Show fit	ets homologous factor
chr7_+_101032021 Show fit	5.19	ENSMUST00000141083.9	Arap1 Ensembl NCBI MGI UniProt Show fit	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr12_-_84265609 Show fit	5.19	ENSMUST00000046266.13 ENSMUST00000220974.2	Mideas Ensembl NCBI MGI UniProt Show fit	mitotic deacetylase associated SANT domain protein
chr4_+_112470794 Show fit	5.16	ENSMUST00000058791.14 ENSMUST00000186969.2	Skint2 Ensembl NCBI MGI UniProt Show fit	selection and upkeep of intraepithelial T cells 2
chr9_+_69360902 Show fit	5.14	ENSMUST00000034756.15 ENSMUST00000123470.8	Anxa2 Ensembl NCBI MGI UniProt Show fit	annexin A2
chr15_+_52575796 Show fit	5.12	ENSMUST00000037115.9	Med30 Ensembl NCBI MGI UniProt Show fit	mediator complex subunit 30
chr3_+_127584449 Show fit	5.10	ENSMUST00000171621.3	Tifa Ensembl NCBI MGI UniProt Show fit	TRAF-interacting protein with forkhead-associated domain
chr12_+_104180795 Show fit	5.09	ENSMUST00000121337.8 ENSMUST00000167049.8 ENSMUST00000101080.2	Serpina3f Ensembl NCBI MGI UniProt Show fit	serine (or cysteine) peptidase inhibitor, clade A, member 3F
chr10_-_18887701 Show fit	5.08	ENSMUST00000105527.2	Tnfaip3 Ensembl NCBI MGI UniProt Show fit	tumor necrosis factor, alpha-induced protein 3
chr16_+_91203123 Show fit	5.08	ENSMUST00000023691.12	Il10rb Ensembl NCBI MGI UniProt Show fit	interleukin 10 receptor, beta
chr5_-_137145030 Show fit	5.06	ENSMUST00000054384.6 ENSMUST00000152207.2	Trim56 Ensembl NCBI MGI UniProt Show fit	tripartite motif-containing 56
chr18_-_32692967 Show fit	4.98	ENSMUST00000174000.2 ENSMUST00000174459.2	Gypc Ensembl NCBI MGI UniProt Show fit	glycophorin C
chr2_+_13579092 Show fit	4.98	ENSMUST00000193675.2	Vim Ensembl NCBI MGI UniProt Show fit	vimentin
chr17_+_34406762 Show fit	4.96	ENSMUST00000041633.15	Tap1 Ensembl NCBI MGI UniProt Show fit	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr11_+_48977888 Show fit	4.89	ENSMUST00000214804.2	Ifi47 Ensembl NCBI MGI UniProt Show fit	interferon gamma inducible protein 47
chr3_+_104696108 Show fit	4.86	ENSMUST00000002303.12	Rhoc Ensembl NCBI MGI UniProt Show fit	ras homolog family member C
chrX_-_74174524 Show fit	4.82	ENSMUST00000114091.8	Mpp1 Ensembl NCBI MGI UniProt Show fit	membrane protein, palmitoylated
chr14_-_55344004 Show fit	4.82	ENSMUST00000036041.15	Ap1g2 Ensembl NCBI MGI UniProt Show fit	adaptor protein complex AP-1, gamma 2 subunit
chr3_+_86131970 Show fit	4.79	ENSMUST00000192145.6 ENSMUST00000194759.6 ENSMUST00000107635.7	Lrba Ensembl NCBI MGI UniProt Show fit	LPS-responsive beige-like anchor
chr1_+_58834532 Show fit	4.76	ENSMUST00000027189.15	Casp8 Ensembl NCBI MGI UniProt Show fit	caspase 8
chr15_+_6599001 Show fit	4.65	ENSMUST00000227175.2	Fyb Ensembl NCBI MGI UniProt Show fit	FYN binding protein
chr8_-_11329656 Show fit	4.62	ENSMUST00000208095.2	Col4a1 Ensembl NCBI MGI UniProt Show fit	collagen, type IV, alpha 1
chr7_-_109215754 Show fit	4.61	ENSMUST00000084738.5	Denn2b Ensembl NCBI MGI UniProt Show fit	DENN domain containing 2B
chr1_-_167112784 Show fit	4.61	ENSMUST00000053686.9	Uck2 Ensembl NCBI MGI UniProt Show fit	uridine-cytidine kinase 2
chr3_-_101743539 Show fit	4.59	ENSMUST00000061831.11	Mab21l3 Ensembl NCBI MGI UniProt Show fit	mab-21-like 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
14.1	70.4	GO:0002268	follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
10.7	42.7	GO:0060376	positive regulation of mast cell differentiation(GO:0060376)
9.8	48.9	GO:0002906	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
9.8	29.3	GO:0002632	regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
9.3	28.0	GO:1905000	regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
8.8	26.5	GO:1904550	chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
7.1	21.3	GO:1902689	negative regulation of NAD metabolic process(GO:1902689) negative regulation of glucose catabolic process to lactate via pyruvate(GO:1904024)
6.8	13.5	GO:0002874	regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
6.2	24.7	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
5.5	16.5	GO:0015688	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
5.3	15.8	GO:1902623	negative regulation of neutrophil migration(GO:1902623)
4.7	38.0	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
4.7	18.8	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
4.6	13.7	GO:0070340	positive regulation of interleukin-18 production(GO:0032741) detection of triacyl bacterial lipopeptide(GO:0042495) response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572) detection of bacterial lipopeptide(GO:0070340)
4.3	17.2	GO:1901740	negative regulation of myoblast fusion(GO:1901740)
4.3	17.2	GO:0002484	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
4.3	12.9	GO:1904629	negative regulation of interleukin-12 biosynthetic process(GO:0045083) response to diterpene(GO:1904629) cellular response to diterpene(GO:1904630) response to glucoside(GO:1904631) cellular response to glucoside(GO:1904632)
4.0	15.9	GO:0060697	positive regulation of phospholipid catabolic process(GO:0060697)
4.0	71.3	GO:1902916	positive regulation of protein polyubiquitination(GO:1902916)
3.9	11.7	GO:0031104	dendrite regeneration(GO:0031104)
3.9	11.7	GO:0014805	smooth muscle adaptation(GO:0014805)
3.8	11.3	GO:1904093	regulation of autophagic cell death(GO:1904092) negative regulation of autophagic cell death(GO:1904093)
3.6	47.2	GO:2001199	negative regulation of dendritic cell differentiation(GO:2001199)
3.6	7.1	GO:2000412	positive regulation of thymocyte migration(GO:2000412)
3.5	21.3	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
3.5	31.7	GO:1903003	positive regulation of protein deubiquitination(GO:1903003)
3.5	10.5	GO:0046967	cytosol to ER transport(GO:0046967)
3.4	30.6	GO:0070245	positive regulation of thymocyte apoptotic process(GO:0070245)
3.2	9.6	GO:0060672	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
3.1	37.6	GO:0070842	aggresome assembly(GO:0070842)
3.0	6.1	GO:0045362	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
2.4	12.2	GO:0097048	dendritic cell apoptotic process(GO:0097048) regulation of dendritic cell apoptotic process(GO:2000668)
2.4	11.8	GO:0010958	regulation of amino acid import(GO:0010958) L-arginine import(GO:0043091) arginine import(GO:0090467)
2.4	7.1	GO:0002305	gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
2.4	9.4	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
2.3	11.4	GO:0070543	response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
2.3	9.0	GO:0071348	cellular response to interleukin-11(GO:0071348)
2.2	4.5	GO:0090027	negative regulation of monocyte chemotaxis(GO:0090027)
2.1	10.6	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
2.0	6.1	GO:0070104	negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
2.0	5.9	GO:1900477	negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
1.9	5.7	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
1.8	7.4	GO:0060265	positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
1.8	43.0	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
1.8	12.4	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
1.8	10.6	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
1.7	79.5	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
1.7	3.3	GO:1990051	activation of protein kinase C activity(GO:1990051)
1.5	3.1	GO:0002859	negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859)
1.5	4.6	GO:0044206	CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206) CMP metabolic process(GO:0046035)
1.5	36.1	GO:0019884	antigen processing and presentation of exogenous antigen(GO:0019884)
1.5	25.4	GO:0051601	exocyst localization(GO:0051601)
1.4	7.2	GO:0034224	cellular response to zinc ion starvation(GO:0034224)
1.4	4.2	GO:0002017	regulation of blood volume by renal aldosterone(GO:0002017)
1.4	13.9	GO:0008063	Toll signaling pathway(GO:0008063)
1.4	4.2	GO:0060010	Sertoli cell fate commitment(GO:0060010)
1.3	5.3	GO:0046226	coumarin catabolic process(GO:0046226)
1.3	10.5	GO:0036135	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
1.3	1.3	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
1.3	2.6	GO:1902527	positive regulation of protein monoubiquitination(GO:1902527)
1.3	6.5	GO:0002678	positive regulation of chronic inflammatory response(GO:0002678)
1.3	42.1	GO:0090022	regulation of neutrophil chemotaxis(GO:0090022)
1.3	3.8	GO:0035874	amiloride transport(GO:0015898) cellular response to copper ion starvation(GO:0035874) response to azide(GO:0097184) cellular response to azide(GO:0097185)
1.3	6.3	GO:0036016	response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
1.3	12.6	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
1.3	41.5	GO:0050901	leukocyte tethering or rolling(GO:0050901)
1.2	9.9	GO:0086023	adrenergic receptor signaling pathway involved in heart process(GO:0086023)
1.2	3.7	GO:0021558	trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of forebrain neuron differentiation(GO:2000978)
1.1	11.4	GO:0002669	positive regulation of T cell tolerance induction(GO:0002666) positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
1.1	5.5	GO:0003349	epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
1.0	8.3	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
1.0	7.0	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
1.0	9.9	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
1.0	7.7	GO:0000821	regulation of arginine metabolic process(GO:0000821)
0.9	7.3	GO:0046601	positive regulation of centriole replication(GO:0046601)
0.9	11.7	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.9	29.5	GO:0048535	lymph node development(GO:0048535)
0.9	7.1	GO:0051715	cytolysis in other organism(GO:0051715)
0.9	2.7	GO:0002386	immune response in mucosal-associated lymphoid tissue(GO:0002386) immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.9	4.4	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.9	4.4	GO:2000523	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.8	6.8	GO:2001183	negative regulation of interleukin-12 secretion(GO:2001183)
0.8	4.2	GO:0072733	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.8	15.9	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.8	14.2	GO:0043320	natural killer cell degranulation(GO:0043320)
0.8	9.2	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.8	3.3	GO:0016999	antibiotic metabolic process(GO:0016999)
0.8	4.1	GO:0035546	detection of virus(GO:0009597) interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549)
0.8	2.4	GO:0098501	polynucleotide dephosphorylation(GO:0098501)
0.8	20.2	GO:0038065	collagen-activated signaling pathway(GO:0038065)
0.8	6.2	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.8	15.3	GO:0071803	positive regulation of podosome assembly(GO:0071803)
0.8	2.3	GO:0046351	disaccharide biosynthetic process(GO:0046351)
0.8	15.9	GO:0060056	mammary gland involution(GO:0060056)
0.7	2.2	GO:0072107	regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107)
0.7	7.2	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406)
0.7	2.1	GO:0002572	pro-T cell differentiation(GO:0002572)
0.7	2.1	GO:0032066	nucleolus to nucleoplasm transport(GO:0032066)
0.7	6.4	GO:1904627	response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.7	9.1	GO:0036462	TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.7	6.2	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.7	2.0	GO:1901738	regulation of vitamin A metabolic process(GO:1901738)
0.7	2.7	GO:0009223	dUMP biosynthetic process(GO:0006226) pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.7	2.0	GO:0061144	alveolar secondary septum development(GO:0061144)
0.7	2.6	GO:0015811	L-cystine transport(GO:0015811)
0.6	1.9	GO:0033082	regulation of extrathymic T cell differentiation(GO:0033082)
0.6	2.5	GO:1901675	negative regulation of histone H3-K27 acetylation(GO:1901675)
0.6	1.9	GO:1904924	negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.6	53.4	GO:0035690	cellular response to drug(GO:0035690)
0.6	20.8	GO:0042832	defense response to protozoan(GO:0042832)
0.6	1.8	GO:0003245	cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.6	6.0	GO:0032494	response to peptidoglycan(GO:0032494)
0.6	14.7	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
0.6	3.5	GO:0006344	maintenance of chromatin silencing(GO:0006344)
0.6	7.0	GO:0019372	lipoxygenase pathway(GO:0019372)
0.6	6.3	GO:0072553	terminal button organization(GO:0072553)
0.6	2.8	GO:0070859	lipid transport involved in lipid storage(GO:0010877) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.6	2.8	GO:0044727	DNA demethylation of male pronucleus(GO:0044727)
0.5	3.2	GO:0048539	bone marrow development(GO:0048539)
0.5	3.2	GO:0098734	protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.5	3.7	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.5	2.1	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
0.5	2.1	GO:0010836	negative regulation of protein ADP-ribosylation(GO:0010836)
0.5	2.5	GO:1990743	protein sialylation(GO:1990743)
0.5	2.5	GO:0032202	telomere assembly(GO:0032202)
0.5	1.0	GO:0002730	regulation of dendritic cell cytokine production(GO:0002730)
0.5	2.9	GO:2000121	regulation of removal of superoxide radicals(GO:2000121)
0.5	1.5	GO:0035992	tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.5	3.3	GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.5	5.2	GO:0006968	cellular defense response(GO:0006968)
0.5	2.8	GO:0061181	regulation of chondrocyte development(GO:0061181)
0.5	2.8	GO:2000819	regulation of nucleotide-excision repair(GO:2000819)
0.5	1.4	GO:0042374	phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.5	0.9	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
0.4	1.3	GO:1903699	tarsal gland development(GO:1903699)
0.4	4.0	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654)
0.4	5.3	GO:0071236	cellular response to antibiotic(GO:0071236)
0.4	1.3	GO:0098749	cerebellar neuron development(GO:0098749)
0.4	16.0	GO:0070098	chemokine-mediated signaling pathway(GO:0070098)
0.4	3.8	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.4	10.1	GO:0051639	actin filament network formation(GO:0051639)
0.4	2.1	GO:1904715	negative regulation of chaperone-mediated autophagy(GO:1904715)
0.4	2.9	GO:0051013	microtubule severing(GO:0051013)
0.4	2.1	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.4	4.0	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.4	3.6	GO:0002553	histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.4	2.8	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.4	16.4	GO:0035458	cellular response to interferon-beta(GO:0035458)
0.4	1.6	GO:1900060	negative regulation of ceramide biosynthetic process(GO:1900060)
0.4	1.5	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.4	3.8	GO:0045059	positive thymic T cell selection(GO:0045059)
0.4	1.1	GO:0045204	MAPK export from nucleus(GO:0045204)
0.4	7.8	GO:0021542	dentate gyrus development(GO:0021542)
0.4	2.9	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.4	8.6	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
0.4	2.1	GO:1990839	response to endothelin(GO:1990839)
0.3	2.8	GO:0048245	eosinophil chemotaxis(GO:0048245)
0.3	4.5	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.3	2.0	GO:0071492	cellular response to UV-A(GO:0071492)
0.3	2.7	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.3	1.3	GO:0071922	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.3	9.3	GO:0030225	macrophage differentiation(GO:0030225)
0.3	6.3	GO:0043249	erythrocyte maturation(GO:0043249)
0.3	1.7	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.3	3.9	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.3	1.6	GO:0071718	sodium-independent icosanoid transport(GO:0071718)
0.3	3.7	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.3	19.9	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.3	2.2	GO:0033034	positive regulation of neutrophil apoptotic process(GO:0033031) positive regulation of myeloid cell apoptotic process(GO:0033034)
0.3	5.1	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.3	1.6	GO:0071847	TNFSF11-mediated signaling pathway(GO:0071847)
0.3	2.4	GO:0006265	DNA topological change(GO:0006265)
0.3	1.1	GO:0015744	succinate transport(GO:0015744)
0.3	3.3	GO:0016554	cytidine to uridine editing(GO:0016554)
0.3	1.8	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.3	1.8	GO:0031584	activation of phospholipase D activity(GO:0031584)
0.3	1.0	GO:0046898	response to cycloheximide(GO:0046898)
0.2	1.2	GO:0046946	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.2	1.5	GO:0035726	common myeloid progenitor cell proliferation(GO:0035726)
0.2	2.9	GO:0097284	hepatocyte apoptotic process(GO:0097284)
0.2	0.7	GO:0030573	bile acid catabolic process(GO:0030573)
0.2	0.7	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.2	2.7	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.2	1.2	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.2	0.7	GO:2000321	positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.2	1.2	GO:1901252	regulation of intracellular transport of viral material(GO:1901252)
0.2	0.9	GO:0006772	thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.2	3.2	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.2	0.7	GO:1901856	negative regulation of cellular respiration(GO:1901856)
0.2	3.4	GO:0010623	programmed cell death involved in cell development(GO:0010623)
0.2	2.2	GO:0008228	opsonization(GO:0008228)
0.2	11.5	GO:0010718	positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.2	1.3	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.2	33.1	GO:0006958	complement activation, classical pathway(GO:0006958)
0.2	1.7	GO:0032735	positive regulation of interleukin-12 production(GO:0032735)
0.2	17.4	GO:0002181	cytoplasmic translation(GO:0002181)
0.2	3.0	GO:0072378	blood coagulation, fibrin clot formation(GO:0072378)
0.2	3.4	GO:0070633	transepithelial transport(GO:0070633)
0.2	1.9	GO:0040031	snRNA modification(GO:0040031)
0.2	0.8	GO:0021993	initiation of neural tube closure(GO:0021993)
0.2	1.7	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.2	2.8	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
0.2	1.4	GO:0042663	regulation of endodermal cell fate specification(GO:0042663)
0.2	1.4	GO:0060023	soft palate development(GO:0060023)
0.2	1.2	GO:0035553	oxidative single-stranded RNA demethylation(GO:0035553)
0.2	1.0	GO:0060931	sinoatrial node cell differentiation(GO:0060921) sinoatrial node cell development(GO:0060931)
0.2	2.1	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.2	4.5	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.2	0.2	GO:0021997	neural plate axis specification(GO:0021997)
0.2	4.7	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.2	1.2	GO:0015671	oxygen transport(GO:0015671)
0.2	0.7	GO:0030091	protein repair(GO:0030091)
0.2	2.8	GO:1902414	protein localization to cell junction(GO:1902414)
0.2	0.5	GO:0006216	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.2	2.1	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
0.2	1.2	GO:0044034	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.2	1.0	GO:0071376	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.2	0.7	GO:0001562	response to protozoan(GO:0001562)
0.2	5.5	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.2	1.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.2	0.9	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.2	2.5	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.2	3.3	GO:0051923	sulfation(GO:0051923)
0.2	2.2	GO:0060481	lobar bronchus epithelium development(GO:0060481)
0.1	8.7	GO:0050873	brown fat cell differentiation(GO:0050873)
0.1	0.8	GO:0060339	negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.1	1.4	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1	2.0	GO:0051014	actin filament severing(GO:0051014)
0.1	1.2	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1	5.4	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.1	1.6	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1	1.2	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.1	0.9	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.1	7.3	GO:0050688	regulation of defense response to virus(GO:0050688)
0.1	4.9	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1	1.3	GO:0098706	ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1	3.5	GO:0060396	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1	2.5	GO:0032506	cytokinetic process(GO:0032506)
0.1	1.7	GO:0002756	MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.1	1.9	GO:0097113	AMPA glutamate receptor clustering(GO:0097113)
0.1	1.1	GO:0010838	positive regulation of keratinocyte proliferation(GO:0010838)
0.1	2.1	GO:0034063	stress granule assembly(GO:0034063)
0.1	1.6	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1	0.7	GO:0006901	vesicle coating(GO:0006901)
0.1	2.2	GO:0030213	hyaluronan biosynthetic process(GO:0030213)
0.1	1.1	GO:0036006	response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.1	8.1	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1	2.9	GO:1900027	regulation of ruffle assembly(GO:1900027)
0.1	10.3	GO:0042098	T cell proliferation(GO:0042098)
0.1	0.5	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1	3.1	GO:0050434	positive regulation of viral transcription(GO:0050434)
0.1	0.3	GO:0000451	rRNA 2'-O-methylation(GO:0000451)
0.1	0.7	GO:0090091	positive regulation of extracellular matrix disassembly(GO:0090091)
0.1	2.3	GO:0006817	phosphate ion transport(GO:0006817)
0.1	8.0	GO:0007229	integrin-mediated signaling pathway(GO:0007229)
0.1	0.5	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1	8.9	GO:0050868	negative regulation of T cell activation(GO:0050868)
0.1	15.3	GO:0009615	response to virus(GO:0009615)
0.1	1.4	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1	8.3	GO:0030279	negative regulation of ossification(GO:0030279)
0.1	1.0	GO:0032261	purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.1	5.1	GO:0030521	androgen receptor signaling pathway(GO:0030521)
0.1	2.4	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.1	1.1	GO:0070307	lens fiber cell development(GO:0070307)
0.1	3.3	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.1	0.6	GO:0016266	O-glycan processing(GO:0016266)
0.1	1.0	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1	3.7	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.1	0.1	GO:0060120	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.1	0.3	GO:1990481	mRNA pseudouridine synthesis(GO:1990481)
0.1	1.4	GO:0006895	Golgi to endosome transport(GO:0006895)
0.1	2.0	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1	0.1	GO:2000229	pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229)
0.1	3.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	1.8	GO:0030574	collagen catabolic process(GO:0030574)
0.1	0.9	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1	3.9	GO:0006730	one-carbon metabolic process(GO:0006730)
0.1	1.7	GO:0046686	response to cadmium ion(GO:0046686)
0.1	5.2	GO:0006334	nucleosome assembly(GO:0006334)
0.1	10.4	GO:0002250	adaptive immune response(GO:0002250)
0.1	1.6	GO:0044030	regulation of DNA methylation(GO:0044030)
0.1	1.8	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.1	0.5	GO:0006903	vesicle targeting(GO:0006903)
0.1	1.3	GO:0048671	negative regulation of collateral sprouting(GO:0048671)
0.1	0.7	GO:0070475	rRNA base methylation(GO:0070475)
0.1	4.0	GO:0043297	apical junction assembly(GO:0043297)
0.1	0.7	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.1	0.8	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.1	1.5	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	0.6	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.1	0.7	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.1	0.2	GO:0001916	positive regulation of T cell mediated cytotoxicity(GO:0001916)
0.1	0.8	GO:0046415	urate metabolic process(GO:0046415)
0.1	10.7	GO:0002377	immunoglobulin production(GO:0002377)
0.1	2.1	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.1	0.4	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.1	2.6	GO:0031572	G2 DNA damage checkpoint(GO:0031572)
0.1	0.9	GO:0015693	magnesium ion transport(GO:0015693)
0.1	4.9	GO:0035914	skeletal muscle cell differentiation(GO:0035914)
0.1	0.3	GO:0007060	male meiosis chromosome segregation(GO:0007060)
0.1	1.8	GO:0045576	mast cell activation(GO:0045576)
0.0	2.2	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	2.5	GO:0002066	columnar/cuboidal epithelial cell development(GO:0002066)
0.0	0.3	GO:0021633	optic nerve structural organization(GO:0021633)
0.0	6.0	GO:0007519	skeletal muscle tissue development(GO:0007519)
0.0	2.6	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	0.5	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.0	7.8	GO:0032147	activation of protein kinase activity(GO:0032147)
0.0	0.2	GO:0060318	definitive erythrocyte differentiation(GO:0060318)
0.0	1.0	GO:0001967	suckling behavior(GO:0001967)
0.0	0.9	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.6	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	2.9	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.0	0.4	GO:0042048	olfactory behavior(GO:0042048)
0.0	0.2	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.0	0.3	GO:0071802	negative regulation of podosome assembly(GO:0071802)
0.0	1.8	GO:0060325	face morphogenesis(GO:0060325)
0.0	1.1	GO:0048701	embryonic cranial skeleton morphogenesis(GO:0048701)
0.0	0.4	GO:0072431	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400)
0.0	0.9	GO:0060441	epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.0	0.1	GO:0033504	floor plate development(GO:0033504)
0.0	0.8	GO:0042491	auditory receptor cell differentiation(GO:0042491)
0.0	1.1	GO:0035088	establishment or maintenance of apical/basal cell polarity(GO:0035088) establishment or maintenance of bipolar cell polarity(GO:0061245)
0.0	3.5	GO:2001236	regulation of extrinsic apoptotic signaling pathway(GO:2001236)
0.0	1.6	GO:0006805	xenobiotic metabolic process(GO:0006805)
0.0	0.5	GO:0000132	establishment of mitotic spindle orientation(GO:0000132)
0.0	0.1	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	1.2	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	1.0	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0	4.8	GO:0060271	cilium morphogenesis(GO:0060271)
0.0	0.8	GO:0007091	metaphase/anaphase transition of mitotic cell cycle(GO:0007091) metaphase/anaphase transition of cell cycle(GO:0044784)
0.0	0.8	GO:0007340	acrosome reaction(GO:0007340)
0.0	0.2	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.4	GO:0046677	response to antibiotic(GO:0046677)
0.0	0.5	GO:0048146	positive regulation of fibroblast proliferation(GO:0048146)
0.0	0.2	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.8	GO:0006446	regulation of translational initiation(GO:0006446)
0.0	0.2	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.1	GO:0061709	reticulophagy(GO:0061709)
0.0	0.3	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.4	GO:0007032	endosome organization(GO:0007032)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
14.1	70.4	GO:0033257	Bcl3/NF-kappaB2 complex(GO:0033257)
6.6	26.5	GO:1990589	ATF4-CREB1 transcription factor complex(GO:1990589)
5.8	81.8	GO:0042612	MHC class I protein complex(GO:0042612)
5.8	69.0	GO:0042613	MHC class II protein complex(GO:0042613)
5.6	45.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
4.7	28.0	GO:0031523	Myb complex(GO:0031523)
4.6	13.7	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
3.5	10.6	GO:1990667	PCSK9-AnxA2 complex(GO:1990667)
3.3	3.3	GO:0042611	MHC protein complex(GO:0042611)
3.1	12.4	GO:0097169	AIM2 inflammasome complex(GO:0097169)
2.4	14.5	GO:0005610	laminin-5 complex(GO:0005610)
2.3	20.9	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
2.3	9.2	GO:0032127	dense core granule membrane(GO:0032127)
2.0	26.1	GO:0020005	symbiont-containing vacuole membrane(GO:0020005)
1.8	14.7	GO:0042825	TAP complex(GO:0042825)
1.3	5.3	GO:0005896	interleukin-6 receptor complex(GO:0005896)
1.0	7.3	GO:0098536	deuterosome(GO:0098536)
1.0	5.1	GO:0031251	PAN complex(GO:0031251)
1.0	25.6	GO:0000145	exocyst(GO:0000145)
1.0	16.3	GO:0035631	CD40 receptor complex(GO:0035631)
1.0	10.5	GO:0045098	type III intermediate filament(GO:0045098)
0.9	4.5	GO:0035976	AP1 complex(GO:0035976)
0.9	6.3	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.8	9.8	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.8	2.4	GO:1904602	serotonin-activated cation-selective channel complex(GO:1904602)
0.8	16.2	GO:0044215	other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.7	13.1	GO:0036038	MKS complex(GO:0036038)
0.7	12.2	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.7	2.1	GO:0070435	Shc-EGFR complex(GO:0070435)
0.7	11.0	GO:0043020	NADPH oxidase complex(GO:0043020)
0.7	7.3	GO:0005796	Golgi lumen(GO:0005796)
0.7	13.9	GO:0042581	specific granule(GO:0042581)
0.7	4.6	GO:0098642	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.7	2.0	GO:0071595	Nem1-Spo7 phosphatase complex(GO:0071595)
0.6	2.9	GO:0071953	elastic fiber(GO:0071953)
0.6	24.6	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.5	32.2	GO:0016235	aggresome(GO:0016235)
0.4	2.1	GO:0070522	ERCC4-ERCC1 complex(GO:0070522)
0.4	1.5	GO:0060171	stereocilium membrane(GO:0060171)
0.4	3.4	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.3	1.0	GO:0032156	septin cytoskeleton(GO:0032156)
0.3	3.2	GO:0042629	mast cell granule(GO:0042629)
0.3	1.6	GO:0035339	SPOTS complex(GO:0035339)
0.3	178.9	GO:0009897	external side of plasma membrane(GO:0009897)
0.3	1.2	GO:0033165	interphotoreceptor matrix(GO:0033165)
0.3	1.5	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.3	2.1	GO:0032389	MutLalpha complex(GO:0032389)
0.3	3.3	GO:0043296	apical junction complex(GO:0043296)
0.3	14.2	GO:0002102	podosome(GO:0002102)
0.3	6.3	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.3	7.2	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.3	2.8	GO:0001940	male pronucleus(GO:0001940)
0.2	0.7	GO:1904511	cortical microtubule plus-end(GO:1903754) cytoplasmic microtubule plus-end(GO:1904511)
0.2	2.2	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.2	1.4	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.2	2.3	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.2	1.8	GO:0097422	tubular endosome(GO:0097422)
0.2	2.3	GO:0042382	paraspeckles(GO:0042382)
0.2	18.2	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.2	1.2	GO:0005833	hemoglobin complex(GO:0005833)
0.2	1.8	GO:0031933	telomeric heterochromatin(GO:0031933)
0.2	2.4	GO:0042788	polysomal ribosome(GO:0042788)
0.2	2.9	GO:0031527	filopodium membrane(GO:0031527)
0.2	2.5	GO:0000138	Golgi trans cisterna(GO:0000138)
0.2	9.3	GO:0016592	mediator complex(GO:0016592)
0.2	8.0	GO:0090544	BAF-type complex(GO:0090544)
0.2	32.6	GO:0030863	cortical cytoskeleton(GO:0030863)
0.2	0.7	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
0.2	3.0	GO:0042101	T cell receptor complex(GO:0042101)
0.2	11.9	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2	9.8	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.2	4.1	GO:0042588	zymogen granule(GO:0042588)
0.2	2.7	GO:0016580	Sin3 complex(GO:0016580)
0.2	2.5	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.2	20.5	GO:0005913	cell-cell adherens junction(GO:0005913)
0.2	8.6	GO:0031201	SNARE complex(GO:0031201)
0.1	1.6	GO:0030891	VCB complex(GO:0030891)
0.1	7.8	GO:0031901	early endosome membrane(GO:0031901)
0.1	28.7	GO:0005923	bicellular tight junction(GO:0005923)
0.1	0.5	GO:0097543	ciliary inversin compartment(GO:0097543)
0.1	2.2	GO:0005771	multivesicular body(GO:0005771)
0.1	15.9	GO:0016363	nuclear matrix(GO:0016363)
0.1	2.7	GO:0055038	recycling endosome membrane(GO:0055038)
0.1	0.4	GO:1990427	stereocilia tip link(GO:0002140) myosin VII complex(GO:0031477) stereocilia tip-link density(GO:1990427) upper tip-link density(GO:1990435)
0.1	4.9	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1	15.1	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.1	0.6	GO:0005593	FACIT collagen trimer(GO:0005593)
0.1	3.2	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.6	GO:0030870	Mre11 complex(GO:0030870)
0.1	5.2	GO:0015030	Cajal body(GO:0015030)
0.1	1.2	GO:0031415	NatA complex(GO:0031415)
0.1	7.5	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1	32.8	GO:0045121	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1	38.5	GO:0005925	focal adhesion(GO:0005925)
0.1	3.1	GO:0005604	basement membrane(GO:0005604)
0.1	4.6	GO:0032432	actin filament bundle(GO:0032432)
0.1	5.4	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1	2.3	GO:0005685	U1 snRNP(GO:0005685)
0.1	4.7	GO:0030118	clathrin coat(GO:0030118)
0.1	0.9	GO:0097542	ciliary tip(GO:0097542)
0.1	2.2	GO:0030904	retromer complex(GO:0030904)
0.1	0.8	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.1	2.2	GO:0005581	collagen trimer(GO:0005581)
0.1	8.4	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.1	1.8	GO:0001917	photoreceptor inner segment(GO:0001917)
0.1	9.9	GO:0001726	ruffle(GO:0001726)
0.1	33.9	GO:0000323	lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1	7.5	GO:0031225	anchored component of membrane(GO:0031225)
0.1	6.6	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.1	1.6	GO:0009925	basal plasma membrane(GO:0009925)
0.1	0.3	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1	0.9	GO:0032426	stereocilium tip(GO:0032426)
0.0	1.5	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.6	GO:0044666	MLL3/4 complex(GO:0044666)
0.0	2.2	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	2.2	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.3	GO:0033503	HULC complex(GO:0033503)
0.0	2.5	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.7	GO:0031519	PcG protein complex(GO:0031519)
0.0	64.6	GO:0070062	extracellular exosome(GO:0070062)
0.0	2.9	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	1.0	GO:0030667	secretory granule membrane(GO:0030667)
0.0	2.3	GO:0031526	brush border membrane(GO:0031526)
0.0	1.2	GO:0045095	keratin filament(GO:0045095)
0.0	53.9	GO:0005615	extracellular space(GO:0005615)
0.0	0.9	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	84.9	GO:0005654	nucleoplasm(GO:0005654)
0.0	0.5	GO:0031012	extracellular matrix(GO:0031012)
0.0	0.6	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	2.0	GO:0000922	spindle pole(GO:0000922)
0.0	6.0	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.4	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	0.6	GO:0005882	intermediate filament(GO:0005882)
0.0	0.7	GO:0005681	spliceosomal complex(GO:0005681)
0.0	0.4	GO:0005922	connexon complex(GO:0005922)
0.0	0.2	GO:0034451	centriolar satellite(GO:0034451)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
14.2	42.6	GO:0098640	integrin binding involved in cell-matrix adhesion(GO:0098640)
8.2	24.7	GO:0031726	receptor signaling protein tyrosine kinase activator activity(GO:0030298) CCR1 chemokine receptor binding(GO:0031726)
8.2	48.9	GO:0042289	MHC class II protein binding(GO:0042289)
6.6	26.5	GO:1990763	arrestin family protein binding(GO:1990763)
5.4	96.5	GO:0046977	TAP binding(GO:0046977)
5.1	30.6	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
4.7	19.0	GO:0070976	TIR domain binding(GO:0070976)
4.7	28.0	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
4.6	13.7	GO:0042497	triacyl lipopeptide binding(GO:0042497)
3.8	30.3	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
3.4	13.4	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
2.9	11.7	GO:0043120	tumor necrosis factor binding(GO:0043120)
2.7	24.7	GO:0035033	histone deacetylase regulator activity(GO:0035033)
2.6	10.2	GO:0019862	IgA binding(GO:0019862)
2.4	28.9	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
2.3	11.4	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
2.3	9.1	GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
1.9	15.2	GO:0061133	endopeptidase activator activity(GO:0061133)
1.8	7.0	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
1.7	11.7	GO:1990254	keratin filament binding(GO:1990254)
1.5	6.0	GO:0035800	deubiquitinase activator activity(GO:0035800)
1.4	36.0	GO:0070628	proteasome binding(GO:0070628)
1.4	4.2	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
1.3	5.3	GO:0004063	aryldialkylphosphatase activity(GO:0004063)
1.3	3.8	GO:0019981	interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
1.3	77.9	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
1.3	3.8	GO:0052597	diamine oxidase activity(GO:0052597) histamine oxidase activity(GO:0052598) methylputrescine oxidase activity(GO:0052599) propane-1,3-diamine oxidase activity(GO:0052600)
1.3	59.6	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
1.2	3.7	GO:0071820	N-box binding(GO:0071820)
1.2	30.9	GO:0042605	peptide antigen binding(GO:0042605)
1.2	10.6	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
1.1	4.5	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
1.1	16.6	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
1.1	6.5	GO:0047844	deoxycytidine deaminase activity(GO:0047844)
1.1	11.8	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
1.0	18.9	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.9	1.8	GO:0046969	histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.9	8.2	GO:0005131	growth hormone receptor binding(GO:0005131)
0.9	9.9	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.9	43.2	GO:0051059	NF-kappaB binding(GO:0051059)
0.9	33.3	GO:0001968	fibronectin binding(GO:0001968)
0.8	7.5	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768)
0.8	7.4	GO:0004875	complement receptor activity(GO:0004875)
0.8	5.7	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.8	6.5	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.8	4.0	GO:0004743	pyruvate kinase activity(GO:0004743)
0.8	12.6	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.8	11.0	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.8	2.3	GO:0004461	lactose synthase activity(GO:0004461)
0.8	2.3	GO:0097677	STAT family protein binding(GO:0097677)
0.7	2.2	GO:0030116	glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.7	2.1	GO:0061749	forked DNA-dependent helicase activity(GO:0061749) flap-structured DNA binding(GO:0070336)
0.7	7.1	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.7	11.6	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.7	3.4	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.7	2.6	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.7	4.6	GO:0004849	uridine kinase activity(GO:0004849)
0.7	2.6	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.6	7.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.6	8.6	GO:0042608	T cell receptor binding(GO:0042608)
0.6	2.4	GO:0046403	polynucleotide 3'-phosphatase activity(GO:0046403)
0.6	2.4	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.6	2.9	GO:0031996	thioesterase binding(GO:0031996)
0.6	1.8	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.6	5.3	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.6	4.0	GO:0050786	RAGE receptor binding(GO:0050786)
0.5	2.2	GO:0050436	microfibril binding(GO:0050436)
0.5	9.5	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.5	14.2	GO:0008009	chemokine activity(GO:0008009)
0.5	3.9	GO:0042609	CD4 receptor binding(GO:0042609)
0.5	2.4	GO:0022850	serotonin-gated cation channel activity(GO:0022850)
0.5	2.9	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.5	3.3	GO:0050694	galactose 3-O-sulfotransferase activity(GO:0050694)
0.5	2.7	GO:0042296	ISG15 transferase activity(GO:0042296)
0.4	14.8	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.4	2.6	GO:0008131	primary amine oxidase activity(GO:0008131)
0.4	9.1	GO:0032036	myosin heavy chain binding(GO:0032036)
0.4	32.3	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.4	2.5	GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.4	1.7	GO:0051435	BH4 domain binding(GO:0051435)
0.4	8.6	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.4	22.5	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.4	4.0	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.4	2.3	GO:0000832	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.4	11.5	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.4	5.7	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.4	4.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.4	2.1	GO:0048408	epidermal growth factor binding(GO:0048408)
0.4	2.1	GO:0001094	TFIID-class transcription factor binding(GO:0001094)
0.3	44.6	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.3	2.1	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.3	4.1	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.3	1.7	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.3	0.9	GO:0016778	diphosphotransferase activity(GO:0016778)
0.3	1.2	GO:0031721	hemoglobin alpha binding(GO:0031721)
0.3	4.6	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.3	2.8	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.3	0.9	GO:1990698	palmitoleoyltransferase activity(GO:1990698)
0.3	0.9	GO:0045030	UTP-activated nucleotide receptor activity(GO:0045030)
0.3	4.2	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.3	4.5	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.3	9.2	GO:0017166	vinculin binding(GO:0017166)
0.3	2.1	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.3	10.3	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.3	1.2	GO:0070137	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.3	1.4	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.3	3.3	GO:1990715	mRNA CDS binding(GO:1990715)
0.3	2.5	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.3	1.9	GO:0031812	G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.3	1.3	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.3	1.9	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.3	2.4	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.3	1.1	GO:0015141	succinate transmembrane transporter activity(GO:0015141)
0.3	1.8	GO:0034452	dynactin binding(GO:0034452)
0.3	6.5	GO:0030553	cGMP binding(GO:0030553)
0.3	3.3	GO:0016274	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.3	8.8	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.2	1.2	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.2	1.7	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.2	4.9	GO:0033038	bitter taste receptor activity(GO:0033038)
0.2	0.7	GO:0008396	oxysterol 7-alpha-hydroxylase activity(GO:0008396)
0.2	12.1	GO:0005484	SNAP receptor activity(GO:0005484)
0.2	4.1	GO:0044548	S100 protein binding(GO:0044548)
0.2	0.7	GO:0038181	bile acid receptor activity(GO:0038181)
0.2	1.4	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.2	2.7	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.2	9.2	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.2	5.1	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.2	1.3	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.2	1.3	GO:0004832	valine-tRNA ligase activity(GO:0004832)
0.2	1.3	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.2	4.0	GO:0030957	Tat protein binding(GO:0030957)
0.2	3.3	GO:0031386	protein tag(GO:0031386)
0.2	3.5	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.2	25.7	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.2	0.2	GO:0005137	interleukin-5 receptor binding(GO:0005137)
0.2	1.2	GO:0035515	oxidative RNA demethylase activity(GO:0035515)
0.2	1.0	GO:0008422	beta-glucosidase activity(GO:0008422)
0.2	10.4	GO:0043015	gamma-tubulin binding(GO:0043015)
0.2	86.2	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.2	1.4	GO:0004782	sulfinoalanine decarboxylase activity(GO:0004782)
0.2	1.4	GO:0015119	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.2	1.3	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2	1.4	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.2	2.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.2	8.5	GO:0003823	antigen binding(GO:0003823)
0.2	1.3	GO:0052851	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2	2.0	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.2	23.4	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.2	11.2	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2	1.7	GO:0070411	I-SMAD binding(GO:0070411)
0.1	1.2	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.7	GO:0016434	rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1	1.8	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.1	18.8	GO:0000149	SNARE binding(GO:0000149)
0.1	47.2	GO:0030246	carbohydrate binding(GO:0030246)
0.1	29.8	GO:0000982	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.1	25.9	GO:0003735	structural constituent of ribosome(GO:0003735)
0.1	1.0	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.1	2.5	GO:0070034	telomerase RNA binding(GO:0070034)
0.1	2.8	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1	2.8	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.1	1.0	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	1.6	GO:0070300	phosphatidic acid binding(GO:0070300)
0.1	1.5	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.1	3.1	GO:0001786	phosphatidylserine binding(GO:0001786)
0.1	0.7	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1	1.0	GO:0030274	LIM domain binding(GO:0030274)
0.1	1.6	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.1	3.1	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1	47.8	GO:0045296	cadherin binding(GO:0045296)
0.1	2.3	GO:0003746	translation elongation factor activity(GO:0003746)
0.1	4.6	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.1	2.8	GO:0045125	bioactive lipid receptor activity(GO:0045125)
0.1	9.7	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.1	1.5	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.1	1.3	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.1	7.2	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1	36.9	GO:0003924	GTPase activity(GO:0003924)
0.1	4.2	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1	0.3	GO:0070039	rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
0.1	0.7	GO:0001223	transcription coactivator binding(GO:0001223)
0.1	0.5	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1	2.7	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.1	1.1	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.1	3.4	GO:0004520	endodeoxyribonuclease activity(GO:0004520)
0.1	1.3	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1	0.4	GO:0032027	myosin light chain binding(GO:0032027)
0.1	0.5	GO:0070410	co-SMAD binding(GO:0070410)
0.1	4.6	GO:0035064	methylated histone binding(GO:0035064)
0.1	1.6	GO:0008327	methyl-CpG binding(GO:0008327)
0.1	2.8	GO:0032452	histone demethylase activity(GO:0032452)
0.1	1.4	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.1	5.1	GO:0003725	double-stranded RNA binding(GO:0003725)
0.1	0.2	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
0.1	1.7	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.1	1.9	GO:0005044	scavenger receptor activity(GO:0005044)
0.1	3.3	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.1	1.2	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1	0.6	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.1	0.9	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.1	1.6	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.1	2.8	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.2	GO:0034211	GTP-dependent protein kinase activity(GO:0034211)
0.0	0.7	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0001849	complement component C1q binding(GO:0001849)
0.0	2.2	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	0.9	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	6.9	GO:0005506	iron ion binding(GO:0005506)
0.0	1.2	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.0	3.7	GO:0004896	cytokine receptor activity(GO:0004896)
0.0	1.5	GO:0071889	14-3-3 protein binding(GO:0071889)
0.0	6.2	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.1	GO:0003875	ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0	0.6	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.5	GO:0001056	RNA polymerase III activity(GO:0001056)
0.0	5.0	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	2.8	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.6	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	1.9	GO:0008173	RNA methyltransferase activity(GO:0008173)
0.0	0.1	GO:0050692	DBD domain binding(GO:0050692)
0.0	1.1	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.6	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	1.6	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.0	0.4	GO:0070513	death domain binding(GO:0070513)
0.0	8.0	GO:0003712	transcription cofactor activity(GO:0003712)
0.0	0.3	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	31.5	GO:0003723	RNA binding(GO:0003723)
0.0	0.4	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0	0.4	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.2	GO:0017160	Ral GTPase binding(GO:0017160)
0.0	1.6	GO:0005178	integrin binding(GO:0005178)
0.0	0.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.7	GO:0050839	cell adhesion molecule binding(GO:0050839)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.2	211.8	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
1.8	45.2	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
1.7	14.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
1.6	61.6	PID IL27 PATHWAY	IL27-mediated signaling events
1.4	18.5	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
1.1	50.1	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
1.0	14.5	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
1.0	26.5	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.8	36.2	PID CD40 PATHWAY	CD40/CD40L signaling
0.8	15.3	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.7	8.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.6	34.4	PID IL12 2PATHWAY	IL12-mediated signaling events
0.6	20.0	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.6	33.5	PID IL4 2PATHWAY	IL4-mediated signaling events
0.5	32.5	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.5	24.3	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.5	34.8	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.5	3.7	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.5	26.6	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.4	29.8	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.4	10.3	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.4	11.8	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.3	6.8	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.3	2.2	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.3	5.6	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.3	12.6	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.2	10.4	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.2	38.8	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.2	11.5	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.2	4.4	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.2	14.5	PID ILK PATHWAY	Integrin-linked kinase signaling
0.2	8.9	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.2	6.1	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2	2.2	PID IL23 PATHWAY	IL23-mediated signaling events
0.2	4.8	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.2	4.4	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.2	11.0	PID RAC1 PATHWAY	RAC1 signaling pathway
0.2	3.5	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.2	1.7	PID NECTIN PATHWAY	Nectin adhesion pathway
0.1	2.0	PID FGF PATHWAY	FGF signaling pathway
0.1	4.8	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1	25.7	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	10.0	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.1	2.4	PID TNF PATHWAY	TNF receptor signaling pathway
0.1	1.4	PID BCR 5PATHWAY	BCR signaling pathway
0.1	1.8	PID IL2 1PATHWAY	IL2-mediated signaling events
0.1	2.4	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.1	0.6	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1	2.2	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	2.3	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.1	2.1	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.1	1.3	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.1	0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.1	1.6	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.1	4.1	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.1	2.7	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	2.7	PID P53 REGULATION PATHWAY	p53 pathway
0.0	1.3	PID ATR PATHWAY	ATR signaling pathway
0.0	4.0	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	2.7	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.5	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.9	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	1.9	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	1.3	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.6	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	1.2	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	4.3	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.7	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.3	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.4	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.0	0.2	PID ARF6 PATHWAY	Arf6 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.6	10.8	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
3.4	13.7	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
3.4	87.2	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
3.0	121.7	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
2.2	118.7	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
1.8	42.5	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.9	47.6	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.9	11.7	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.9	9.8	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.7	21.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.6	17.5	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.6	3.0	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.6	8.2	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.5	5.3	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.5	10.5	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.5	9.0	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.5	4.0	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.5	3.8	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.5	12.0	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.4	3.1	REACTOME P75NTR SIGNALS VIA NFKB	Genes involved in p75NTR signals via NF-kB
0.4	27.6	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.4	38.1	REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	Genes involved in Antigen processing-Cross presentation
0.4	17.2	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.4	12.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.4	13.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.4	10.3	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.3	36.0	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.3	1.5	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.3	11.6	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.3	11.3	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.2	29.8	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.2	8.3	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.2	6.5	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.2	6.0	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.2	2.8	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.2	3.0	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.2	7.3	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.2	8.9	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.2	3.4	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2	7.7	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.2	3.3	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.2	2.7	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	2.1	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1	5.2	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.1	3.3	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.1	2.9	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.1	5.7	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.1	4.6	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.1	3.7	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	2.4	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.1	5.2	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	11.9	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.1	10.9	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.1	1.6	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.1	7.2	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	8.9	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.1	2.5	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.1	10.9	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	5.8	REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	Genes involved in trans-Golgi Network Vesicle Budding
0.1	0.9	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	2.5	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.1	2.1	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1	1.1	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.1	3.9	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.1	3.8	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1	2.2	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.1	0.9	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.7	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.8	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.8	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	1.3	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	5.8	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.6	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	1.0	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.5	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.5	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.9	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.4	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.6	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.5	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.5	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.4	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.4	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	2.0	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.4	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.6	REACTOME MEMBRANE TRAFFICKING	Genes involved in Membrane Trafficking
0.0	0.5	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.1	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome

Results for Rela_Rel_Nfkb1

Z-value: 2.88

Motif logo

Transcription factors associated with Rela_Rel_Nfkb1

Activity-expression correlation:

Activity profile of Rela_Rel_Nfkb1 motif

Sorted Z-values of Rela_Rel_Nfkb1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Rela_Rel_Nfkb1

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: