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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Rfx5

Z-value: 1.75

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Transcription factors associated with Rfx5

Gene Symbol Gene ID Gene Info
Rfx5
ENSMUSG00000005774.13 Rfx5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Rfx5mm39_v1_chr3_+_94861386_948615370.491.1e-05Click!

Activity profile of Rfx5 motif

Sorted Z-values of Rfx5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Rfx5

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr17_+_34617784 27.22 ENSMUST00000114175.8
ENSMUST00000139063.8
ENSMUST00000078615.12
BC051142
cDNA sequence BC051142
chr17_+_34364206 20.46 ENSMUST00000041982.9
ENSMUST00000171231.8
H2-DMb2
histocompatibility 2, class II, locus Mb2
chr19_+_37364791 19.68 ENSMUST00000012587.4
Kif11
kinesin family member 11
chr17_+_34457868 17.93 ENSMUST00000095342.11
ENSMUST00000167280.8
ENSMUST00000236838.2
H2-Ob
histocompatibility 2, O region beta locus
chr17_+_34482183 17.41 ENSMUST00000040828.7
ENSMUST00000237342.2
ENSMUST00000237866.2
H2-Ab1
histocompatibility 2, class II antigen A, beta 1
chr18_+_60936910 17.38 ENSMUST00000097563.9
ENSMUST00000050487.16
ENSMUST00000167610.2
Cd74
CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
chr17_+_34416707 17.35 ENSMUST00000025196.9
Psmb8
proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)
chr7_+_126690525 15.40 ENSMUST00000056288.7
ENSMUST00000206102.2
AI467606
expressed sequence AI467606
chr17_+_34524841 15.26 ENSMUST00000235530.2
H2-Eb1
histocompatibility 2, class II antigen E beta
chr17_+_34524884 14.89 ENSMUST00000074557.11
H2-Eb1
histocompatibility 2, class II antigen E beta
chr17_+_34372046 14.60 ENSMUST00000114232.4
H2-DMb1
histocompatibility 2, class II, locus Mb1
chr17_+_34416689 14.03 ENSMUST00000173441.9
Psmb8
proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)
chr17_+_36172210 13.64 ENSMUST00000074259.15
ENSMUST00000174873.2
Nrm
nurim (nuclear envelope membrane protein)
chr17_+_35658131 12.39 ENSMUST00000071951.14
ENSMUST00000116598.10
ENSMUST00000078205.14
ENSMUST00000076256.8
H2-Q7
histocompatibility 2, Q region locus 7
chr17_+_34544632 11.84 ENSMUST00000050325.10
H2-Eb2
histocompatibility 2, class II antigen E beta2
chr17_+_34406523 11.83 ENSMUST00000170086.8
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr17_+_35598583 11.57 ENSMUST00000081435.5
H2-Q4
histocompatibility 2, Q region locus 4
chr17_+_34406762 11.57 ENSMUST00000041633.15
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr17_-_37794434 11.14 ENSMUST00000016427.11
ENSMUST00000171139.3
H2-M2
histocompatibility 2, M region locus 2
chr19_-_10460238 11.09 ENSMUST00000235392.2
ENSMUST00000237522.2
ENSMUST00000038842.5
Ppp1r32
protein phosphatase 1, regulatory subunit 32
chr17_+_36172235 10.77 ENSMUST00000172931.2
Nrm
nurim (nuclear envelope membrane protein)
chr7_-_30364394 10.40 ENSMUST00000019697.9
Haus5
HAUS augmin-like complex, subunit 5
chr10_-_128579879 9.86 ENSMUST00000026414.9
Dgka
diacylglycerol kinase, alpha
chr17_-_34219225 9.79 ENSMUST00000238098.2
ENSMUST00000087189.7
ENSMUST00000173075.3
ENSMUST00000172912.8
ENSMUST00000236740.2
ENSMUST00000025181.18
H2-K1
histocompatibility 2, K1, K region
chr17_+_34354556 9.36 ENSMUST00000236322.2
ENSMUST00000237402.2
H2-DMa
histocompatibility 2, class II, locus DMa
chr11_+_106167541 8.86 ENSMUST00000044462.4
Tcam1
testicular cell adhesion molecule 1
chr17_-_34406193 8.69 ENSMUST00000173831.3
Psmb9
proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
chr7_-_24145107 8.49 ENSMUST00000205776.2
Irgc1
immunity-related GTPase family, cinema 1
chr17_+_37581103 8.21 ENSMUST00000038580.7
H2-M3
histocompatibility 2, M region locus 3
chr14_+_40794817 7.62 ENSMUST00000189865.7
Dydc1
DPY30 domain containing 1
chr9_-_21202545 7.51 ENSMUST00000215619.2
Cdkn2d
cyclin dependent kinase inhibitor 2D
chr4_-_126219465 7.50 ENSMUST00000102616.8
Tekt2
tektin 2
chr6_-_124756645 7.27 ENSMUST00000147669.2
ENSMUST00000128697.8
ENSMUST00000032218.10
ENSMUST00000112475.9
Lrrc23
leucine rich repeat containing 23
chr7_+_44926925 7.26 ENSMUST00000210861.2
Slc6a21
solute carrier family 6 member 21
chr9_-_21202353 6.47 ENSMUST00000086374.8
Cdkn2d
cyclin dependent kinase inhibitor 2D
chr4_-_126219434 6.39 ENSMUST00000131113.8
Tekt2
tektin 2
chr9_-_21202693 6.31 ENSMUST00000213407.2
Cdkn2d
cyclin dependent kinase inhibitor 2D
chr2_-_28453374 6.30 ENSMUST00000028161.6
Cel
carboxyl ester lipase
chr14_+_40794893 6.25 ENSMUST00000161837.2
Dydc1
DPY30 domain containing 1
chr19_+_34194990 6.23 ENSMUST00000119603.2
Stambpl1
STAM binding protein like 1
chr14_+_53607470 5.80 ENSMUST00000103652.5
Trav14n-3
T cell receptor alpha variable 14N-3
chrX_+_44179759 5.78 ENSMUST00000040002.4
Prr32
proline rich 32
chr17_-_25105277 5.48 ENSMUST00000234583.2
ENSMUST00000234968.2
ENSMUST00000044252.7
Nubp2
nucleotide binding protein 2
chr16_-_31898088 5.39 ENSMUST00000023467.9
Pak2
p21 (RAC1) activated kinase 2
chr5_+_139135966 5.07 ENSMUST00000026975.11
ENSMUST00000196441.2
Dnaaf5
dynein, axonemal assembly factor 5
chr5_-_123663440 4.82 ENSMUST00000197682.6
Gm49027
predicted gene, 49027
chr5_+_11392646 4.65 ENSMUST00000179482.2
Speer1
spermatogenesis associated glutamate (E)-rich protein 1
chr5_+_11821653 4.65 ENSMUST00000178158.2
Gm8926
predicted gene 8926
chr5_+_11733203 4.39 ENSMUST00000178989.2
Gm8922
predicted gene 8922
chr9_-_51013361 4.37 ENSMUST00000170947.3
Hoatz
HOATZ cilia and flagella associated protein
chr5_+_11553780 4.31 ENSMUST00000179375.2
Gm8906
predicted gene 8906
chrX_+_158480304 4.30 ENSMUST00000123433.8
Sh3kbp1
SH3-domain kinase binding protein 1
chr4_-_115638209 4.24 ENSMUST00000106521.2
Tex38
testis expressed 38
chr8_-_85794611 4.14 ENSMUST00000177563.2
Gm5741
predicted gene 5741
chr5_+_11307124 4.11 ENSMUST00000177727.2
Gm8890
predicted gene 8890
chr5_+_11178835 4.09 ENSMUST00000178863.2
Gm8879
predicted gene 8879
chr5_+_11467593 4.08 ENSMUST00000179679.2
Gm8897
predicted gene 8897
chr8_+_41205245 3.96 ENSMUST00000096663.5
Adam25
a disintegrin and metallopeptidase domain 25 (testase 2)
chr1_-_182929025 3.91 ENSMUST00000171366.7
Disp1
dispatched RND transporter family member 1
chr4_-_116485118 3.91 ENSMUST00000030456.14
Nasp
nuclear autoantigenic sperm protein (histone-binding)
chr5_+_11234174 3.86 ENSMUST00000168407.3
Gm5861
predicted gene 5861
chr8_+_106154266 3.84 ENSMUST00000067305.8
Lrrc36
leucine rich repeat containing 36
chr8_-_105236506 3.81 ENSMUST00000064576.8
Terb1
telomere repeat binding bouquet formation protein 1
chr10_-_123032821 3.40 ENSMUST00000219619.2
ENSMUST00000020334.9
Usp15
ubiquitin specific peptidase 15
chr14_+_53886861 3.19 ENSMUST00000103660.4
Trav15-2-dv6-2
T cell receptor alpha variable 15-2-DV6-2
chr8_+_82582953 3.17 ENSMUST00000109851.3
Inpp4b
inositol polyphosphate-4-phosphatase, type II
chr8_+_41246310 2.97 ENSMUST00000056331.8
Adam20
a disintegrin and metallopeptidase domain 20
chr7_-_101570393 2.92 ENSMUST00000106965.8
ENSMUST00000106968.8
ENSMUST00000106967.8
Lrrc51
leucine rich repeat containing 51
chr8_+_41276027 2.89 ENSMUST00000066814.7
Adam39
a disintegrin and metallopeptidase domain 39
chr4_-_112291169 2.81 ENSMUST00000058605.3
Skint9
selection and upkeep of intraepithelial T cells 9
chr13_+_25015653 2.67 ENSMUST00000038039.3
ENSMUST00000223804.2
Tdp2
tyrosyl-DNA phosphodiesterase 2
chr1_-_53031814 2.31 ENSMUST00000190831.7
ENSMUST00000190726.2
1700019D03Rik
RIKEN cDNA 1700019D03 gene
chr7_+_100186399 2.19 ENSMUST00000120454.3
Coa4
cytochrome c oxidase assembly factor 4
chr10_-_123032881 2.07 ENSMUST00000220377.2
Usp15
ubiquitin specific peptidase 15
chr5_-_134485081 2.05 ENSMUST00000111244.5
Gtf2ird1
general transcription factor II I repeat domain-containing 1
chr4_+_107825529 2.01 ENSMUST00000106713.5
ENSMUST00000238795.2
Slc1a7
solute carrier family 1 (glutamate transporter), member 7
chr7_-_101570382 1.99 ENSMUST00000098236.9
Lrrc51
leucine rich repeat containing 51
chr19_-_10460031 1.84 ENSMUST00000236733.2
Ppp1r32
protein phosphatase 1, regulatory subunit 32
chr1_-_155022501 1.80 ENSMUST00000027744.10
Mr1
major histocompatibility complex, class I-related
chr14_+_55855484 1.70 ENSMUST00000002395.8
Rec8
REC8 meiotic recombination protein
chrX_+_111150171 1.64 ENSMUST00000164272.3
ENSMUST00000132037.2
4933403O08Rik
RIKEN cDNA 4933403O08 gene
chr7_-_45343785 1.56 ENSMUST00000040636.9
Sec1
secretory blood group 1
chr7_-_33065747 1.54 ENSMUST00000179248.2
Scgb2b20
secretoglobin, family 2B, member 20
chr8_+_94941192 1.43 ENSMUST00000079961.14
ENSMUST00000212824.2
Nup93
nucleoporin 93
chr17_+_25105617 1.39 ENSMUST00000117890.8
ENSMUST00000168265.8
ENSMUST00000120943.8
ENSMUST00000068508.13
ENSMUST00000119829.8
Spsb3
splA/ryanodine receptor domain and SOCS box containing 3
chr7_+_80764564 1.35 ENSMUST00000119083.2
Slc28a1
solute carrier family 28 (sodium-coupled nucleoside transporter), member 1
chr10_-_7539009 1.24 ENSMUST00000163085.8
ENSMUST00000159917.8
Pcmt1
protein-L-isoaspartate (D-aspartate) O-methyltransferase 1
chr2_+_121978156 1.17 ENSMUST00000102476.5
B2m
beta-2 microglobulin
chr5_-_124327776 1.05 ENSMUST00000159677.8
Pitpnm2
phosphatidylinositol transfer protein, membrane-associated 2
chr5_-_36987917 1.00 ENSMUST00000031002.10
Man2b2
mannosidase 2, alpha B2
chr7_+_100186259 0.95 ENSMUST00000054310.4
Coa4
cytochrome c oxidase assembly factor 4
chr5_-_125371162 0.91 ENSMUST00000127148.2
Scarb1
scavenger receptor class B, member 1
chr11_+_61395964 0.86 ENSMUST00000102657.10
B9d1
B9 protein domain 1
chr1_+_134333506 0.70 ENSMUST00000027726.14
Cyb5r1
cytochrome b5 reductase 1
chr1_-_74932266 0.65 ENSMUST00000006721.3
Cryba2
crystallin, beta A2
chr15_+_36179676 0.50 ENSMUST00000171205.3
Spag1
sperm associated antigen 1
chr11_+_72332167 0.27 ENSMUST00000045633.6
Mybbp1a
MYB binding protein (P160) 1a
chr5_-_140346132 0.17 ENSMUST00000196130.5
Snx8
sorting nexin 8

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.8 23.4 GO:0046967 cytosol to ER transport(GO:0046967)
6.0 17.9 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
5.8 17.4 GO:0002343 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
4.8 92.0 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
4.7 9.4 GO:0002477 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481)
2.4 9.8 GO:0002485 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
1.5 19.7 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
1.4 20.3 GO:0048102 autophagic cell death(GO:0048102)
1.3 5.4 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
1.3 3.9 GO:0035638 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
1.1 19.0 GO:0036159 inner dynein arm assembly(GO:0036159)
1.1 5.5 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
1.0 13.9 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.9 36.9 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.7 40.1 GO:0019882 antigen processing and presentation(GO:0019882)
0.7 9.9 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.5 7.2 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.4 3.8 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.4 2.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.4 3.9 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.3 1.4 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.2 5.5 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.2 1.4 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.2 2.0 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.2 3.1 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.2 7.3 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 3.2 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 1.0 GO:0006013 mannose metabolic process(GO:0006013)
0.1 10.4 GO:0051225 spindle assembly(GO:0051225)
0.1 1.2 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.1 1.7 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.1 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 2.7 GO:0006302 double-strand break repair(GO:0006302)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
10.6 127.3 GO:0042613 MHC class II protein complex(GO:0042613)
6.7 40.1 GO:1990111 spermatoproteasome complex(GO:1990111)
3.0 44.9 GO:0042611 MHC protein complex(GO:0042611)
2.9 23.4 GO:0042825 TAP complex(GO:0042825)
2.5 20.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
1.2 10.4 GO:0070652 HAUS complex(GO:0070652)
1.1 24.4 GO:0005652 nuclear lamina(GO:0005652)
0.7 13.9 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.4 3.8 GO:0070187 telosome(GO:0070187)
0.3 5.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.3 19.7 GO:0005876 spindle microtubule(GO:0005876)
0.3 1.7 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.2 6.3 GO:0042588 zymogen granule(GO:0042588)
0.1 0.3 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.9 GO:0036038 MKS complex(GO:0036038)
0.0 2.7 GO:0016235 aggresome(GO:0016235)
0.0 3.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.9 GO:0031528 microvillus membrane(GO:0031528)
0.0 4.3 GO:0030139 endocytic vesicle(GO:0030139)
0.0 2.3 GO:0036126 sperm flagellum(GO:0036126)
0.0 1.4 GO:0005643 nuclear pore(GO:0005643)
0.0 1.2 GO:0031526 brush border membrane(GO:0031526)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.8 23.4 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
3.1 79.7 GO:0023026 MHC class II protein complex binding(GO:0023026)
2.3 33.8 GO:0046977 TAP binding(GO:0046977)
2.1 6.3 GO:0004771 sterol esterase activity(GO:0004771) retinyl-palmitate esterase activity(GO:0050253)
1.5 40.1 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
1.4 36.8 GO:0042605 peptide antigen binding(GO:0042605)
1.1 5.5 GO:0061649 ubiquitinated histone binding(GO:0061649)
1.0 20.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.8 3.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.6 9.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.6 13.9 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.5 1.6 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.5 1.4 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.4 10.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.3 3.9 GO:0015197 peptide transporter activity(GO:0015197)
0.2 5.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.2 1.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.2 0.9 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 5.1 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.9 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 5.5 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 2.0 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.1 12.8 GO:0005178 integrin binding(GO:0005178)
0.1 2.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 3.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 7.3 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.1 1.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.0 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 2.7 GO:0030145 manganese ion binding(GO:0030145)
0.0 6.2 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 8.5 GO:0003924 GTPase activity(GO:0003924)
0.0 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 4.3 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.4 PID MYC PATHWAY C-MYC pathway
0.1 23.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 9.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 2.7 PID CD40 PATHWAY CD40/CD40L signaling
0.0 4.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.2 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 3.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 24.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.7 38.2 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.4 11.8 REACTOME KINESINS Genes involved in Kinesins
0.3 20.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.3 5.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 9.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 17.4 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.2 3.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 4.3 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 2.0 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.4 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 1.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules