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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Runx2_Bcl11a

Z-value: 2.88

Motif logo

Transcription factors associated with Runx2_Bcl11a

Gene Symbol Gene ID Gene Info
ENSMUSG00000039153.18 Runx2
ENSMUSG00000000861.16 Bcl11a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Runx2mm39_v1_chr17_-_45125537_451256840.413.5e-04Click!
Bcl11amm39_v1_chr11_+_24028173_240282200.181.2e-01Click!

Activity profile of Runx2_Bcl11a motif

Sorted Z-values of Runx2_Bcl11a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Runx2_Bcl11a

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr18_-_35782412 33.11 ENSMUST00000025211.6
marginal zone B and B1 cell-specific protein 1
chr11_-_106205320 30.15 ENSMUST00000167143.2
CD79B antigen
chr7_-_103477126 28.41 ENSMUST00000023934.8
hemoglobin, beta adult s chain
chr3_+_103767581 28.30 ENSMUST00000029433.9
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr7_+_142559414 26.28 ENSMUST00000082008.12
ENSMUST00000105925.8
ENSMUST00000105924.8
tetraspanin 32
chrX_-_100311824 26.16 ENSMUST00000033664.14
interleukin 2 receptor, gamma chain
chr3_-_59009231 25.71 ENSMUST00000085040.5
G protein-coupled receptor 171
chr6_-_87510200 25.61 ENSMUST00000113637.9
ENSMUST00000071024.7
Rho GTPase activating protein 25
chr7_+_142559375 24.59 ENSMUST00000075172.12
ENSMUST00000105923.8
tetraspanin 32
chr7_+_142558783 23.82 ENSMUST00000009396.13
tetraspanin 32
chr6_+_41248311 22.74 ENSMUST00000103281.3
T cell receptor beta, variable 29
chr7_+_142558837 22.70 ENSMUST00000207211.2
tetraspanin 32
chr11_-_79414542 22.62 ENSMUST00000179322.2
ecotropic viral integration site 2b
chrX_-_7956682 20.87 ENSMUST00000033505.7
Wiskott-Aldrich syndrome
chr15_-_78377926 20.34 ENSMUST00000163494.3
interleukin 2 receptor, beta chain
chr6_+_41118120 20.31 ENSMUST00000103273.3
T cell receptor beta, variable 15
chr5_-_113957318 19.87 ENSMUST00000201194.4
selectin, platelet (p-selectin) ligand
chr8_-_3744167 19.28 ENSMUST00000005678.6
Fc receptor, IgE, low affinity II, alpha polypeptide
chr7_-_140596811 19.09 ENSMUST00000081924.5
interferon induced transmembrane protein 6
chr2_-_58050494 18.78 ENSMUST00000028175.7
cytohesin 1 interacting protein
chr14_-_56499690 18.65 ENSMUST00000015581.6
granzyme B
chr8_-_110305672 16.72 ENSMUST00000074898.8
haptoglobin
chr16_-_18884431 16.48 ENSMUST00000200235.2
immunoglobulin lambda constant 3
chr1_+_135060994 16.47 ENSMUST00000167080.3
protein tyrosine phosphatase, non-receptor type 7
chr5_+_90916370 16.01 ENSMUST00000031319.8
pro-platelet basic protein
chr19_+_3985186 16.00 ENSMUST00000165711.3
ENSMUST00000162708.7
ENSMUST00000236920.2
unc-93 homolog B1, TLR signaling regulator
chr11_-_46280336 15.95 ENSMUST00000020664.13
IL2 inducible T cell kinase
chr15_-_9529898 15.30 ENSMUST00000228782.2
ENSMUST00000003981.6
interleukin 7 receptor
chr16_+_23338960 15.19 ENSMUST00000211460.2
ENSMUST00000210658.2
ENSMUST00000209198.2
ENSMUST00000210371.2
ENSMUST00000211499.2
ENSMUST00000210795.2
ENSMUST00000209422.2
predicted gene 45338
receptor transporter protein 4
chr5_-_113957362 15.07 ENSMUST00000202555.2
selectin, platelet (p-selectin) ligand
chr12_-_112824506 15.01 ENSMUST00000021729.9
G protein-coupled receptor 132
chr1_+_135060431 14.98 ENSMUST00000187985.7
ENSMUST00000049449.11
protein tyrosine phosphatase, non-receptor type 7
chr5_+_86219593 14.91 ENSMUST00000198435.5
ENSMUST00000031171.9
signal transducing adaptor family member 1
chr16_-_92622972 14.66 ENSMUST00000023673.14
runt related transcription factor 1
chr11_-_106278892 14.46 ENSMUST00000106813.9
ENSMUST00000141146.2
intercellular adhesion molecule 2
chrX_-_100312629 14.37 ENSMUST00000117736.2
predicted gene 20489
chr11_-_46280298 14.30 ENSMUST00000109237.9
IL2 inducible T cell kinase
chr11_-_87766350 14.22 ENSMUST00000049768.4
eosinophil peroxidase
chr4_+_134847949 14.14 ENSMUST00000056977.14
runt related transcription factor 3
chr7_+_142559475 14.07 ENSMUST00000143512.3
tetraspanin 32
chr16_-_45940602 13.63 ENSMUST00000023336.10
CD96 antigen
chr13_-_20008397 12.69 ENSMUST00000222664.2
ENSMUST00000065335.3
G protein-coupled receptor 141
chr11_-_46280281 12.68 ENSMUST00000101306.4
IL2 inducible T cell kinase
chr1_+_170104889 12.65 ENSMUST00000179976.3
SH2 domain containing 1B1
chr7_+_44221791 12.55 ENSMUST00000002274.10
napsin A aspartic peptidase
chr6_-_69521891 12.46 ENSMUST00000103356.4
immunoglobulin kappa variable 4-57-1
chr13_-_113237505 12.33 ENSMUST00000224282.2
ENSMUST00000023897.7
granzyme A
chr6_+_41128636 11.74 ENSMUST00000103274.4
T cell receptor beta, variable 16
chr7_+_43086432 11.58 ENSMUST00000070518.4
natural killer cell group 7 sequence
chr15_+_80456775 11.38 ENSMUST00000229980.2
GRB2-related adaptor protein 2
chr11_-_69786324 11.35 ENSMUST00000001631.7
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chrX_+_106299484 11.35 ENSMUST00000101294.9
ENSMUST00000118820.8
ENSMUST00000120971.8
G protein-coupled receptor 174
chr6_+_87755046 11.32 ENSMUST00000032133.5
glycoprotein 9 (platelet)
chr19_-_20368029 11.21 ENSMUST00000235280.2
annexin A1
chrX_-_56384089 10.96 ENSMUST00000033468.11
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr2_-_32277773 10.85 ENSMUST00000050785.14
lipocalin 2
chr11_-_83540175 10.82 ENSMUST00000001008.6
chemokine (C-C motif) ligand 3
chr6_+_123100382 10.71 ENSMUST00000032248.8
C-type lectin domain family 4, member a2
chr7_-_140845156 10.60 ENSMUST00000123525.2
interferon regulatory factor 7
chrX_+_158480304 10.50 ENSMUST00000123433.8
SH3-domain kinase binding protein 1
chrX_+_106192510 10.47 ENSMUST00000147521.8
ENSMUST00000167673.2
purinergic receptor P2Y, G-protein coupled 10B
chr15_-_66673425 10.45 ENSMUST00000168589.8
src-like adaptor
chr7_+_24069680 10.40 ENSMUST00000205428.2
ENSMUST00000171904.3
ENSMUST00000205626.2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr6_+_123100272 10.27 ENSMUST00000041779.13
C-type lectin domain family 4, member a2
chr1_-_162687488 10.27 ENSMUST00000134098.8
ENSMUST00000111518.3
flavin containing monooxygenase 1
chr7_+_43086554 10.20 ENSMUST00000206741.2
natural killer cell group 7 sequence
chr5_+_105667254 9.92 ENSMUST00000067924.13
ENSMUST00000150981.2
leucine rich repeat containing 8 family, member C
chr5_-_105287405 9.91 ENSMUST00000100961.5
ENSMUST00000031235.13
ENSMUST00000197799.2
ENSMUST00000199629.2
ENSMUST00000196677.5
ENSMUST00000100962.8
guanylate-binding protein 9
guanylate-binding protein 8
guanylate binding protein 4
chr8_+_89020845 9.91 ENSMUST00000098521.4
adenylate cyclase 7
chr6_-_48747767 9.84 ENSMUST00000204036.2
GTPase, IMAP family member 3
chr17_+_47906985 9.75 ENSMUST00000182539.8
cyclin D3
chr18_-_62313019 9.67 ENSMUST00000053640.5
adrenergic receptor, beta 2
chr10_-_62343516 9.62 ENSMUST00000020271.13
serglycin
chr11_+_48967411 9.56 ENSMUST00000109202.3
interferon gamma inducible protein 47
chr17_+_33857030 9.41 ENSMUST00000052079.8
PML-RAR alpha-regulated adaptor molecule 1
chr15_+_6599001 9.39 ENSMUST00000227175.2
FYN binding protein
chr9_+_72345267 9.36 ENSMUST00000183809.8
meiosis-specific nuclear structural protein 1
chrX_-_100777806 9.29 ENSMUST00000056614.7
chemokine (C-X-C motif) receptor 3
chr15_-_97742134 9.21 ENSMUST00000119670.8
ENSMUST00000116409.9
histone deacetylase 7
chr5_-_107873883 9.17 ENSMUST00000159263.3
growth factor independent 1 transcription repressor
chr17_+_35235552 9.14 ENSMUST00000007245.8
ENSMUST00000172499.2
von Willebrand factor A domain containing 7
chr3_-_135313982 9.14 ENSMUST00000132668.8
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
chr16_-_16681839 9.07 ENSMUST00000100136.4
immunoglobulin lambda-like polypeptide 1
chr5_-_113970664 9.06 ENSMUST00000199109.2
selectin, platelet (p-selectin) ligand
chr19_-_10807409 9.03 ENSMUST00000080292.12
CD6 antigen
chr1_-_172418058 9.03 ENSMUST00000065679.8
SLAM family member 8
chr4_+_135899678 8.98 ENSMUST00000061721.6
E2F transcription factor 2
chr1_-_192880260 8.93 ENSMUST00000161367.2
TRAF3 interacting protein 3
chr11_+_95733109 8.91 ENSMUST00000107714.9
ENSMUST00000107711.8
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr11_-_52173391 8.83 ENSMUST00000086844.10
transcription factor 7, T cell specific
chr7_-_44888220 8.80 ENSMUST00000210372.2
ENSMUST00000209779.2
ENSMUST00000098461.10
ENSMUST00000211373.2
CD37 antigen
chr19_-_10807285 8.76 ENSMUST00000039043.15
CD6 antigen
chr17_+_56056977 8.71 ENSMUST00000025004.7
adhesion G protein-coupled receptor E4
chr19_+_4175934 8.56 ENSMUST00000169055.10
ENSMUST00000135257.11
ENSMUST00000138593.10
ENSMUST00000140267.10
ENSMUST00000137579.6
ENSMUST00000139987.10
ENSMUST00000150627.11
ENSMUST00000151401.11
ENSMUST00000153654.11
transmembrane protein 134
chr17_+_8463886 8.55 ENSMUST00000231545.2
chemokine (C-C motif) receptor 6
chr1_-_164763091 8.51 ENSMUST00000027860.8
chemokine (C motif) ligand 1
chr10_+_28544356 8.35 ENSMUST00000060409.13
ENSMUST00000056097.11
ENSMUST00000105516.9
thymocyte selection associated
chr7_-_100512579 8.33 ENSMUST00000142885.2
ENSMUST00000008462.11
RELT tumor necrosis factor receptor
chr15_-_97742045 8.31 ENSMUST00000120683.8
histone deacetylase 7
chr16_-_19060440 8.16 ENSMUST00000103751.3
immunoglobulin lambda variable 3
chr1_+_107456731 8.16 ENSMUST00000182198.8
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10
chrX_+_149330371 7.86 ENSMUST00000066337.13
ENSMUST00000112715.2
aminolevulinic acid synthase 2, erythroid
chr9_-_70842090 7.86 ENSMUST00000034731.10
lipase, hepatic
chr16_-_18880821 7.85 ENSMUST00000200568.2
immunoglobulin lambda constant 1
chr13_-_55169100 7.74 ENSMUST00000148221.8
ENSMUST00000052949.13
hexokinase 3
chr9_+_108880221 7.71 ENSMUST00000200629.5
ENSMUST00000200515.5
ENSMUST00000197689.5
ENSMUST00000196954.5
ENSMUST00000198376.5
ENSMUST00000197483.5
ENSMUST00000198295.5
shisa family member 5
chr17_+_34457868 7.70 ENSMUST00000095342.11
ENSMUST00000167280.8
ENSMUST00000236838.2
histocompatibility 2, O region beta locus
chr1_-_173569301 7.59 ENSMUST00000042610.15
ENSMUST00000127730.2
interferon activated gene 207
chr1_-_173859321 7.55 ENSMUST00000059226.7
interferon activated gene 205
chr6_+_123099615 7.49 ENSMUST00000161636.8
ENSMUST00000161365.8
C-type lectin domain family 4, member a2
chr12_-_4924341 7.46 ENSMUST00000137337.8
ENSMUST00000045921.14
major facilitator superfamily domain containing 2B
chr3_-_15397325 7.45 ENSMUST00000108361.2
predicted gene 9733
chr1_-_192883743 7.40 ENSMUST00000043550.11
TRAF3 interacting protein 3
chr13_-_55169000 7.32 ENSMUST00000153665.8
hexokinase 3
chrX_-_9335525 7.32 ENSMUST00000015484.10
cytochrome b-245, beta polypeptide
chr2_-_73316053 7.23 ENSMUST00000102680.8
WAS/WASL interacting protein family, member 1
chr4_-_42773987 7.16 ENSMUST00000095114.5
chemokine (C-C motif) ligand 21A (serine)
chr17_-_45125537 7.13 ENSMUST00000113571.10
runt related transcription factor 2
chr8_+_84852609 7.08 ENSMUST00000093380.5
podocan-like 1
chr7_-_140597465 6.93 ENSMUST00000211330.2
interferon induced transmembrane protein 6
chr17_+_34544632 6.88 ENSMUST00000050325.10
histocompatibility 2, class II antigen E beta2
chr17_+_37180437 6.87 ENSMUST00000060524.11
tripartite motif-containing 10
chr5_+_145063568 6.86 ENSMUST00000138922.2
actin related protein 2/3 complex, subunit 1B
chr17_-_34506744 6.85 ENSMUST00000174751.2
ENSMUST00000040655.14
histocompatibility 2, class II antigen A, alpha
chr19_-_10807220 6.85 ENSMUST00000174176.3
CD6 antigen
chr2_-_101479846 6.79 ENSMUST00000078494.6
ENSMUST00000160722.8
ENSMUST00000160037.8
recombination activating 1
intraflagellar transport associated protein
chr6_+_70700207 6.77 ENSMUST00000103407.3
ENSMUST00000199487.2
immunoglobulin kappa joining 3
chr7_-_43182595 6.75 ENSMUST00000205503.2
CD33 antigen
chr6_-_69626340 6.69 ENSMUST00000198328.2
immunoglobulin kappa variable 4-53
chr14_-_122153185 6.69 ENSMUST00000055475.9
G protein-coupled receptor 18
chr17_+_31783708 6.66 ENSMUST00000097352.11
ENSMUST00000237248.2
ENSMUST00000235869.2
ENSMUST00000175806.9
Pbx/knotted 1 homeobox
chr10_+_79852487 6.65 ENSMUST00000099501.10
Rho GTPase activating protein 45
chr2_-_173060647 6.62 ENSMUST00000109116.3
ENSMUST00000029018.14
Z-DNA binding protein 1
chr11_-_16958647 6.62 ENSMUST00000102881.10
pleckstrin
chr9_+_51124983 6.61 ENSMUST00000034554.9
POU domain, class 2, associating factor 1
chr14_+_53756760 6.60 ENSMUST00000103585.4
T cell receptor alpha variable 11
chr10_+_79852750 6.60 ENSMUST00000105373.8
Rho GTPase activating protein 45
chr17_+_35413415 6.58 ENSMUST00000025262.6
ENSMUST00000173600.2
lymphotoxin B
chr9_+_110867807 6.56 ENSMUST00000197575.2
lactotransferrin
chrX_-_12026594 6.53 ENSMUST00000043441.13
BCL6 interacting corepressor
chr9_+_108880158 6.50 ENSMUST00000198708.5
shisa family member 5
chr2_+_26969384 6.49 ENSMUST00000091233.7
ADAMTS-like 2
chr2_-_26561294 6.48 ENSMUST00000028283.2
lipocalin 4
chr11_-_120930193 6.45 ENSMUST00000026159.6
CD7 antigen
chr7_-_3848050 6.39 ENSMUST00000108615.10
ENSMUST00000119469.2
paired-Ig-like receptor A2
chr14_+_53743184 6.21 ENSMUST00000103583.5
T cell receptor alpha variable 10
chr10_+_118276949 6.16 ENSMUST00000068592.5
interferon gamma
chr6_+_41098273 6.15 ENSMUST00000103270.4
T cell receptor beta, variable 13-2
chr1_-_173740467 6.14 ENSMUST00000009340.10
interferon activated gene 211
chr11_+_82955917 6.14 ENSMUST00000038038.8
schlafen 2
chr6_-_130363837 6.13 ENSMUST00000032288.6
killer cell lectin-like receptor, subfamily A, member 1
chr10_+_61007733 6.10 ENSMUST00000122261.8
ENSMUST00000121297.8
ENSMUST00000035894.12
thymus, brain and testes associated
chr5_-_113968483 6.04 ENSMUST00000100874.6
selectin, platelet (p-selectin) ligand
chr3_-_86049988 6.02 ENSMUST00000029722.7
ribosomal protein S3A1
chr17_-_35285146 5.99 ENSMUST00000174190.2
ENSMUST00000097337.8
megakaryocyte and platelet inhibitory receptor G6b
chr3_+_90421742 5.93 ENSMUST00000048138.8
S100 calcium binding protein A13
chr7_+_126895463 5.92 ENSMUST00000106306.9
ENSMUST00000120857.8
integrin alpha L
chr1_-_171434882 5.89 ENSMUST00000111277.2
ENSMUST00000004827.14
lymphocyte antigen 9
chr7_+_28136861 5.87 ENSMUST00000108292.9
ENSMUST00000108289.8
glia maturation factor, gamma
chr3_+_130906434 5.86 ENSMUST00000098611.4
lymphoid enhancer binding factor 1
chr11_+_87684299 5.86 ENSMUST00000020779.11
myeloperoxidase
chr7_-_3723381 5.76 ENSMUST00000078451.7
paired Ig-like receptor B
chr7_+_4240697 5.74 ENSMUST00000117550.2
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
chr4_+_114914880 5.73 ENSMUST00000161601.8
T cell acute lymphocytic leukemia 1
chr8_-_112417633 5.71 ENSMUST00000034435.7
chymotrypsinogen B1
chr16_-_75706161 5.71 ENSMUST00000114239.9
SAM domain, SH3 domain and nuclear localization signals, 1
chr11_+_83637766 5.69 ENSMUST00000070832.3
WAP four-disulfide core domain 21
chr10_+_51356728 5.69 ENSMUST00000102894.6
ENSMUST00000219661.2
ENSMUST00000219696.2
ENSMUST00000217706.2
leukocyte immunoglobulin-like receptor, subfamily B, member 4B
predicted gene, 49339
chr19_-_4175837 5.64 ENSMUST00000121402.2
ENSMUST00000117831.8
aryl-hydrocarbon receptor-interacting protein
chrX_+_158410528 5.62 ENSMUST00000073094.10
SH3-domain kinase binding protein 1
chr17_+_48623157 5.58 ENSMUST00000049614.13
RIKEN cDNA B430306N03 gene
chr1_-_38704028 5.58 ENSMUST00000039827.14
AF4/FMR2 family, member 3
chr7_+_28140352 5.48 ENSMUST00000078845.13
glia maturation factor, gamma
chr7_-_44888532 5.45 ENSMUST00000033063.15
CD37 antigen
chr1_-_144651157 5.44 ENSMUST00000027603.4
regulator of G-protein signaling 18
chr1_-_171434944 5.43 ENSMUST00000068878.14
lymphocyte antigen 9
chrX_+_41591476 5.42 ENSMUST00000115070.8
ENSMUST00000153948.2
SH2 domain containing 1A
chr1_+_74414354 5.42 ENSMUST00000187516.7
ENSMUST00000027368.6
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
chr14_+_54198389 5.41 ENSMUST00000103678.4
T cell receptor delta variable 2-2
chr15_+_6552270 5.39 ENSMUST00000226412.2
FYN binding protein
chr7_+_30264835 5.36 ENSMUST00000043850.14
IGF-like family receptor 1
chr4_-_46404224 5.36 ENSMUST00000107764.9
hemogen
chr7_+_26534730 5.35 ENSMUST00000005685.15
cytochrome P450, family 2, subfamily a, polypeptide 5
chr10_-_79624758 5.28 ENSMUST00000020573.13
protease, serine 57
chr14_+_54433095 5.26 ENSMUST00000103717.3
T cell receptor alpha joining 24
chrX_+_106193060 5.24 ENSMUST00000125676.8
ENSMUST00000180182.2
purinergic receptor P2Y, G-protein coupled 10B
chr7_-_3828640 5.17 ENSMUST00000189095.7
ENSMUST00000094911.5
ENSMUST00000153846.8
ENSMUST00000108619.8
ENSMUST00000108620.8
predicted gene 15448
chr4_+_114914607 5.17 ENSMUST00000136946.8
T cell acute lymphocytic leukemia 1
chr13_-_37234213 5.16 ENSMUST00000164727.8
coagulation factor XIII, A1 subunit
chr5_+_90920294 5.16 ENSMUST00000031320.8
platelet factor 4
chr7_+_126184108 5.15 ENSMUST00000039522.8
apolipoprotein B receptor
chr17_-_45903494 5.12 ENSMUST00000163492.8
solute carrier family 29 (nucleoside transporters), member 1
chr15_+_97259060 5.11 ENSMUST00000228521.2
ENSMUST00000226495.2
PC-esterase domain containing 1B
chr3_+_145855929 5.10 ENSMUST00000098524.5
mucolipin 2
chr17_+_34482183 5.10 ENSMUST00000040828.7
ENSMUST00000237342.2
ENSMUST00000237866.2
histocompatibility 2, class II antigen A, beta 1
chrX_+_41591410 5.07 ENSMUST00000005839.11
SH2 domain containing 1A
chr9_+_123603605 5.06 ENSMUST00000180093.2
chemokine (C-C motif) receptor 9
chr1_+_172328768 5.03 ENSMUST00000111228.2
transgelin 2
chr1_+_36806015 5.02 ENSMUST00000185871.2
zeta-chain (TCR) associated protein kinase
chr7_-_44888465 4.98 ENSMUST00000210078.2
CD37 antigen

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
12.3 36.8 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
11.9 130.7 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
10.0 50.0 GO:0050902 leukocyte adhesive activation(GO:0050902)
7.0 20.9 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
6.9 34.4 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
6.5 19.5 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
5.9 35.7 GO:0032831 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
5.2 15.7 GO:0002215 defense response to nematode(GO:0002215)
5.0 24.8 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
4.8 14.3 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
3.9 19.7 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
3.9 11.7 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
3.8 15.3 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
3.8 11.4 GO:0071846 actin filament debranching(GO:0071846)
3.7 18.6 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
3.7 18.3 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
3.6 10.9 GO:0060217 hemangioblast cell differentiation(GO:0060217)
3.2 12.7 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
2.9 8.6 GO:1904156 DN2 thymocyte differentiation(GO:1904155) DN3 thymocyte differentiation(GO:1904156)
2.8 11.3 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
2.8 19.3 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
2.6 7.9 GO:0030845 regulation of inositol-polyphosphate 5-phosphatase activity(GO:0010924) positive regulation of inositol-polyphosphate 5-phosphatase activity(GO:0010925) phospholipase C-inhibiting G-protein coupled receptor signaling pathway(GO:0030845) regulation of cell diameter(GO:0060305)
2.6 7.7 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of antigen processing and presentation of peptide antigen(GO:0002584)
2.5 7.6 GO:0042694 muscle cell fate specification(GO:0042694)
2.4 9.7 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
2.4 9.6 GO:0033368 protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382)
2.4 7.2 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
2.3 16.4 GO:0002370 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
2.3 46.6 GO:0001865 NK T cell differentiation(GO:0001865)
2.2 11.2 GO:0097350 neutrophil clearance(GO:0097350)
2.2 10.9 GO:0034371 chylomicron remodeling(GO:0034371)
2.1 6.3 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
2.0 9.8 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
1.9 5.8 GO:0035702 monocyte homeostasis(GO:0035702)
1.9 13.6 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
1.9 13.1 GO:0015862 uridine transport(GO:0015862)
1.9 5.6 GO:0002148 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
1.8 27.6 GO:0001771 immunological synapse formation(GO:0001771)
1.8 5.4 GO:0070839 divalent metal ion export(GO:0070839)
1.8 8.9 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
1.8 10.6 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
1.7 5.2 GO:0021664 rhombomere formation(GO:0021594) rhombomere 3 formation(GO:0021660) rhombomere 5 morphogenesis(GO:0021664) rhombomere 5 formation(GO:0021666)
1.7 5.1 GO:0002344 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
1.7 6.8 GO:0071895 odontoblast differentiation(GO:0071895)
1.7 11.7 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
1.7 6.6 GO:0030091 protein repair(GO:0030091)
1.6 8.2 GO:0090366 DNA cytosine deamination(GO:0070383) positive regulation of mRNA modification(GO:0090366)
1.6 6.6 GO:0051673 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) membrane disruption in other organism(GO:0051673) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
1.6 6.5 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
1.5 1.5 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
1.5 9.0 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
1.5 5.8 GO:0001803 type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
1.4 5.6 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
1.4 6.8 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
1.3 6.5 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
1.3 20.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
1.3 3.8 GO:1900195 positive regulation of oocyte maturation(GO:1900195)
1.2 3.7 GO:0006713 glucocorticoid catabolic process(GO:0006713)
1.2 14.9 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
1.2 9.9 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
1.2 3.7 GO:0018879 biphenyl metabolic process(GO:0018879)
1.2 4.8 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
1.2 22.9 GO:0043383 negative T cell selection(GO:0043383)
1.2 4.8 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
1.1 13.4 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
1.1 3.3 GO:0002380 immunoglobulin secretion involved in immune response(GO:0002380)
1.1 8.8 GO:0002568 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
1.1 6.6 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
1.1 3.2 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
1.1 4.3 GO:0048388 endosomal lumen acidification(GO:0048388)
1.1 3.2 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
1.1 10.6 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
1.0 4.2 GO:0046722 lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
1.0 4.9 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
1.0 6.9 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
1.0 4.8 GO:0031296 B cell costimulation(GO:0031296)
1.0 4.8 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
1.0 2.9 GO:0021698 cerebellar cortex structural organization(GO:0021698) regulation of Rap protein signal transduction(GO:0032487) negative regulation of integrin activation(GO:0033624)
0.9 4.5 GO:0009597 detection of virus(GO:0009597)
0.9 1.8 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.9 14.2 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.9 2.7 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.9 7.0 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.9 2.6 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904)
0.9 5.2 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
0.9 5.2 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.9 10.4 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.8 2.5 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.8 3.3 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.8 4.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.8 4.9 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.8 10.5 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118)
0.8 4.8 GO:0032827 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.8 7.0 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.8 3.0 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.8 10.5 GO:0043615 astrocyte cell migration(GO:0043615)
0.8 3.0 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.7 7.5 GO:0002051 osteoblast fate commitment(GO:0002051)
0.7 14.6 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.7 1.5 GO:2000538 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.7 5.8 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.7 2.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.7 10.5 GO:0006968 cellular defense response(GO:0006968)
0.7 5.5 GO:1903874 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707) ferrous iron transmembrane transport(GO:1903874)
0.7 4.0 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.7 3.9 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.7 2.0 GO:1990051 negative regulation of phospholipase C activity(GO:1900275) activation of protein kinase C activity(GO:1990051)
0.7 9.8 GO:0071361 cellular response to ethanol(GO:0071361)
0.7 6.5 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.7 13.7 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.6 1.3 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.6 3.9 GO:0061017 hepatoblast differentiation(GO:0061017)
0.6 12.1 GO:0070995 NADPH oxidation(GO:0070995)
0.6 11.4 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.6 1.3 GO:0002352 B cell negative selection(GO:0002352)
0.6 5.5 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.6 6.6 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.6 5.9 GO:0032264 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.6 2.4 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.6 8.1 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.6 2.3 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.6 5.5 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.5 2.7 GO:0061056 sclerotome development(GO:0061056)
0.5 3.3 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.5 3.8 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.5 1.6 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.5 2.1 GO:0051329 interphase(GO:0051325) mitotic interphase(GO:0051329)
0.5 6.9 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.5 1.6 GO:0001810 regulation of type I hypersensitivity(GO:0001810) positive regulation of type I hypersensitivity(GO:0001812) type I hypersensitivity(GO:0016068)
0.5 8.9 GO:0070986 left/right axis specification(GO:0070986)
0.5 6.8 GO:0046485 ether lipid metabolic process(GO:0046485)
0.5 6.6 GO:0043129 surfactant homeostasis(GO:0043129)
0.5 1.5 GO:2000321 positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.5 2.0 GO:0045896 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.5 1.5 GO:0021759 globus pallidus development(GO:0021759)
0.5 3.0 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.5 1.0 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.5 32.1 GO:0035456 response to interferon-beta(GO:0035456)
0.5 2.9 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.5 2.9 GO:0072539 T-helper 17 cell differentiation(GO:0072539)
0.5 3.9 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.5 3.9 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.5 1.4 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.5 1.4 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.5 6.2 GO:1902563 regulation of neutrophil degranulation(GO:0043313) regulation of neutrophil activation(GO:1902563)
0.5 14.1 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.5 85.8 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.5 1.8 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.5 0.9 GO:0002604 regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.4 1.3 GO:2000847 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.4 1.3 GO:1903660 regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.4 2.2 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.4 6.5 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.4 2.6 GO:0018094 protein polyglycylation(GO:0018094)
0.4 4.7 GO:0000042 protein targeting to Golgi(GO:0000042)
0.4 1.7 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.4 5.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.4 5.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.4 4.9 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.4 7.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.4 5.9 GO:0016576 histone dephosphorylation(GO:0016576)
0.4 13.6 GO:0051205 protein insertion into membrane(GO:0051205)
0.4 3.1 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.4 1.1 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.4 1.9 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.4 3.0 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.4 3.0 GO:0006450 regulation of translational fidelity(GO:0006450)
0.4 5.2 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.4 2.5 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.4 1.1 GO:0006550 isoleucine catabolic process(GO:0006550)
0.3 1.0 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.3 1.0 GO:1904501 negative regulation of mitotic cell cycle, embryonic(GO:0045976) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.3 5.7 GO:0002820 negative regulation of adaptive immune response(GO:0002820)
0.3 2.6 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.3 11.3 GO:0043029 T cell homeostasis(GO:0043029)
0.3 66.0 GO:0002377 immunoglobulin production(GO:0002377)
0.3 2.2 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.3 1.2 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.3 8.9 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.3 1.8 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.3 5.9 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.3 1.2 GO:0019046 release from viral latency(GO:0019046)
0.3 2.4 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.3 1.8 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.3 2.1 GO:0070889 platelet alpha granule organization(GO:0070889)
0.3 1.4 GO:0001757 somite specification(GO:0001757)
0.3 0.3 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.3 1.4 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
0.3 4.8 GO:0010818 T cell chemotaxis(GO:0010818)
0.3 1.9 GO:0009313 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.3 1.9 GO:0036005 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.3 1.1 GO:0072023 ascending thin limb development(GO:0072021) thick ascending limb development(GO:0072023) metanephric ascending thin limb development(GO:0072218) metanephric thick ascending limb development(GO:0072233)
0.3 1.6 GO:0002159 desmosome assembly(GO:0002159)
0.3 14.9 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.3 2.4 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.3 2.6 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.3 2.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.3 0.5 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.3 3.0 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.3 5.3 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.2 1.2 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.2 2.7 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.2 1.7 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.2 1.2 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.2 9.8 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.2 0.7 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.2 2.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.2 21.2 GO:0030101 natural killer cell activation(GO:0030101)
0.2 1.9 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.2 0.7 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.2 1.6 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2 3.2 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.2 3.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.2 18.5 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.2 1.4 GO:0050915 sensory perception of sour taste(GO:0050915)
0.2 1.8 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.2 0.9 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.2 1.3 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.2 2.1 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.2 0.6 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.2 1.5 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.2 0.6 GO:0002355 detection of tumor cell(GO:0002355)
0.2 1.5 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.2 1.9 GO:0030916 otic vesicle formation(GO:0030916)
0.2 2.7 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037)
0.2 1.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.2 1.6 GO:0042730 fibrinolysis(GO:0042730)
0.2 1.2 GO:1900245 negative regulation of MDA-5 signaling pathway(GO:0039534) positive regulation of MDA-5 signaling pathway(GO:1900245)
0.2 6.5 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.2 5.7 GO:0050872 white fat cell differentiation(GO:0050872)
0.2 2.5 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 0.4 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.2 1.4 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.2 1.9 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.2 1.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 5.0 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.2 1.5 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.2 1.5 GO:0046638 positive regulation of alpha-beta T cell differentiation(GO:0046638)
0.2 2.4 GO:0001553 luteinization(GO:0001553)
0.2 7.0 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.2 0.9 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.2 1.7 GO:0014060 regulation of epinephrine secretion(GO:0014060) negative regulation of epinephrine secretion(GO:0032811)
0.2 2.0 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 0.7 GO:0001887 selenium compound metabolic process(GO:0001887)
0.2 0.9 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418)
0.2 1.4 GO:0031053 primary miRNA processing(GO:0031053)
0.2 0.7 GO:0060948 cardiac vascular smooth muscle cell development(GO:0060948)
0.2 1.0 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.2 1.9 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.2 2.5 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.2 0.7 GO:0002191 formation of cytoplasmic translation initiation complex(GO:0001732) cap-dependent translational initiation(GO:0002191)
0.2 3.4 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.2 1.5 GO:0050718 positive regulation of interleukin-1 secretion(GO:0050716) positive regulation of interleukin-1 beta secretion(GO:0050718)
0.2 26.5 GO:0002250 adaptive immune response(GO:0002250)
0.2 0.6 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.2 2.3 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.2 0.6 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.2 0.5 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 0.9 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 3.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 2.2 GO:0042448 progesterone metabolic process(GO:0042448)
0.1 0.7 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.1 2.5 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 1.0 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.4 GO:0046072 dTDP biosynthetic process(GO:0006233) dTDP metabolic process(GO:0046072)
0.1 8.6 GO:0045576 mast cell activation(GO:0045576)
0.1 0.6 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.1 0.3 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.1 0.7 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.6 GO:0050812 regulation of acyl-CoA biosynthetic process(GO:0050812)
0.1 1.9 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 1.0 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 3.4 GO:0016578 histone deubiquitination(GO:0016578)
0.1 2.6 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.1 9.6 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.7 GO:0015889 cobalamin transport(GO:0015889)
0.1 4.6 GO:0006414 translational elongation(GO:0006414)
0.1 0.8 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1 2.1 GO:0051026 chiasma assembly(GO:0051026)
0.1 0.5 GO:1901301 cochlear nucleus development(GO:0021747) regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.8 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.1 3.8 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 0.9 GO:0071451 removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451)
0.1 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.9 GO:0007527 adult somatic muscle development(GO:0007527)
0.1 0.8 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.1 1.8 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.1 4.3 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 1.0 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.5 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.1 5.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 6.5 GO:1901998 toxin transport(GO:1901998)
0.1 0.7 GO:0090383 phagosome acidification(GO:0090383)
0.1 2.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 5.6 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.1 2.7 GO:0016180 snRNA processing(GO:0016180)
0.1 0.6 GO:2001204 regulation of osteoclast development(GO:2001204)
0.1 4.5 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 5.4 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 5.9 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 0.4 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 9.7 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 1.3 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.1 3.7 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 1.5 GO:0072678 T cell migration(GO:0072678)
0.1 0.4 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 0.7 GO:0043144 snoRNA processing(GO:0043144)
0.1 1.3 GO:2000352 negative regulation of endothelial cell apoptotic process(GO:2000352)
0.1 4.6 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.1 0.4 GO:0030730 sequestering of triglyceride(GO:0030730)
0.1 2.9 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.1 1.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 0.6 GO:0061042 vascular wound healing(GO:0061042)
0.1 8.6 GO:1903955 positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 8.1 GO:0030217 T cell differentiation(GO:0030217)
0.1 1.4 GO:0060612 adipose tissue development(GO:0060612)
0.1 0.4 GO:0006363 termination of RNA polymerase I transcription(GO:0006363) diacylglycerol catabolic process(GO:0046340)
0.1 0.5 GO:0016266 O-glycan processing(GO:0016266)
0.1 1.4 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.1 0.3 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 1.8 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.1 1.8 GO:0002076 osteoblast development(GO:0002076)
0.1 1.2 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.1 4.7 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 0.6 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.3 GO:0019323 pentose catabolic process(GO:0019323)
0.1 1.2 GO:0051310 metaphase plate congression(GO:0051310)
0.1 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 1.1 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.1 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.1 0.6 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.3 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.2 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.1 1.0 GO:0048853 forebrain morphogenesis(GO:0048853)
0.1 1.2 GO:0051382 kinetochore assembly(GO:0051382)
0.1 1.6 GO:0051923 sulfation(GO:0051923)
0.1 0.7 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 1.5 GO:0031648 protein destabilization(GO:0031648)
0.1 0.7 GO:0051503 adenine nucleotide transport(GO:0051503)
0.1 1.1 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.1 0.8 GO:0001782 B cell homeostasis(GO:0001782)
0.1 2.0 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.1 4.1 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.6 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 1.7 GO:0060009 Sertoli cell development(GO:0060009)
0.1 0.9 GO:1901739 regulation of myoblast fusion(GO:1901739) positive regulation of myoblast fusion(GO:1901741)
0.1 0.2 GO:1990091 sodium-dependent self proteolysis(GO:1990091)
0.1 0.6 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.1 0.2 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773) regulation of AMPA glutamate receptor clustering(GO:1904717)
0.1 1.0 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.1 0.3 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.4 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.6 GO:0048733 sebaceous gland development(GO:0048733)
0.1 1.6 GO:0030488 tRNA methylation(GO:0030488)
0.1 0.4 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.8 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.4 GO:0002097 tRNA wobble base modification(GO:0002097)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 3.1 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.2 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.0 1.5 GO:0006953 acute-phase response(GO:0006953)
0.0 4.0 GO:0008033 tRNA processing(GO:0008033)
0.0 15.7 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 2.1 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.4 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 1.2 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 1.6 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 3.4 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 0.5 GO:0036295 cellular response to increased oxygen levels(GO:0036295) response to increased oxygen levels(GO:0036296)
0.0 1.2 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 5.1 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.4 GO:0046037 GMP metabolic process(GO:0046037)
0.0 2.1 GO:1901799 negative regulation of proteasomal protein catabolic process(GO:1901799)
0.0 0.3 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0 1.4 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.4 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.3 GO:0035909 aorta morphogenesis(GO:0035909)
0.0 0.6 GO:1901099 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.2 GO:0097324 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 1.1 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0021564 vagus nerve development(GO:0021564)
0.0 1.4 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.7 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 0.2 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 1.0 GO:0060976 coronary vasculature development(GO:0060976)
0.0 0.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 3.8 GO:0045444 fat cell differentiation(GO:0045444)
0.0 0.4 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.1 GO:1903299 regulation of glucokinase activity(GO:0033131) regulation of hexokinase activity(GO:1903299)
0.0 1.2 GO:0006405 RNA export from nucleus(GO:0006405)
0.0 0.6 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 2.4 GO:0007051 spindle organization(GO:0007051)
0.0 0.6 GO:0031424 keratinization(GO:0031424)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0061187 histone H4-K20 demethylation(GO:0035574) regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.9 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.0 0.1 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.9 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 5.1 GO:0034097 response to cytokine(GO:0034097)
0.0 0.1 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.3 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.5 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
22.3 111.5 GO:0070442 integrin alphaIIb-beta3 complex(GO:0070442)
9.0 45.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
4.3 21.6 GO:0044194 cytolytic granule(GO:0044194)
3.9 39.4 GO:0019815 B cell receptor complex(GO:0019815)
3.8 64.5 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
3.6 10.9 GO:0033193 Lsd1/2 complex(GO:0033193)
2.7 13.6 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
2.5 24.6 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
2.2 33.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
1.9 20.8 GO:0042629 mast cell granule(GO:0042629)
1.8 5.3 GO:0060205 secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
1.7 6.9 GO:0036284 tubulobulbar complex(GO:0036284)
1.6 19.6 GO:0042613 MHC class II protein complex(GO:0042613)
1.6 22.3 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
1.5 3.1 GO:0035631 CD40 receptor complex(GO:0035631)
1.5 4.6 GO:0032997 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
1.5 1.5 GO:1990423 RZZ complex(GO:1990423)
1.4 15.0 GO:0097208 alveolar lamellar body(GO:0097208)
1.3 7.9 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
1.3 6.5 GO:0097059 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
1.3 3.9 GO:0060187 cell pole(GO:0060187)
1.2 14.9 GO:0032009 early phagosome(GO:0032009)
1.2 4.8 GO:1990682 CSF1-CSF1R complex(GO:1990682)
1.1 5.6 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
1.1 5.4 GO:0030312 external encapsulating structure(GO:0030312)
1.1 10.6 GO:1990462 omegasome(GO:1990462)
0.8 6.5 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.8 4.8 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.8 8.6 GO:0097524 sperm plasma membrane(GO:0097524)
0.7 8.8 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.7 2.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.7 9.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.7 2.6 GO:0060171 stereocilium membrane(GO:0060171)
0.6 3.8 GO:0032133 chromosome passenger complex(GO:0032133) germinal vesicle(GO:0042585)
0.6 6.9 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.6 10.6 GO:0097512 cardiac myofibril(GO:0097512)
0.6 4.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.5 0.5 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.5 4.7 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.5 27.2 GO:0001772 immunological synapse(GO:0001772)
0.5 1.5 GO:0071001 U4/U6 snRNP(GO:0071001)
0.5 2.8 GO:0005683 U7 snRNP(GO:0005683)
0.5 1.4 GO:0070877 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.5 7.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.4 11.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.4 5.9 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.4 1.2 GO:0034457 Mpp10 complex(GO:0034457)
0.4 135.3 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.4 4.5 GO:0000235 astral microtubule(GO:0000235)
0.4 1.6 GO:0005914 spot adherens junction(GO:0005914)
0.4 223.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.4 1.6 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.4 4.0 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.4 1.9 GO:0071953 elastic fiber(GO:0071953)
0.4 7.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.3 4.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.3 9.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.3 19.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.3 1.9 GO:0097418 neurofibrillary tangle(GO:0097418)
0.3 1.9 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.3 1.5 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.3 9.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.3 11.4 GO:0008180 COP9 signalosome(GO:0008180)
0.2 0.7 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.2 11.2 GO:0005719 nuclear euchromatin(GO:0005719)
0.2 14.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 1.5 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.2 6.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 0.8 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.2 2.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 4.4 GO:0070938 contractile ring(GO:0070938)
0.2 16.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 0.6 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 2.9 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.2 7.5 GO:0097546 ciliary base(GO:0097546)
0.2 1.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.2 18.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 2.5 GO:0042788 polysomal ribosome(GO:0042788)
0.1 2.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 2.8 GO:0032039 integrator complex(GO:0032039)
0.1 1.0 GO:0098536 deuterosome(GO:0098536)
0.1 6.6 GO:0031519 PcG protein complex(GO:0031519)
0.1 0.8 GO:0061574 ASAP complex(GO:0061574)
0.1 1.9 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1 25.2 GO:0005884 actin filament(GO:0005884)
0.1 1.5 GO:0061702 inflammasome complex(GO:0061702)
0.1 1.6 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 2.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 0.3 GO:0055087 Ski complex(GO:0055087)
0.1 0.3 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 1.3 GO:0005642 annulate lamellae(GO:0005642)
0.1 1.0 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.4 GO:0030478 actin cap(GO:0030478)
0.1 11.1 GO:0005930 axoneme(GO:0005930)
0.1 0.9 GO:1990635 proximal dendrite(GO:1990635)
0.1 2.2 GO:0097440 apical dendrite(GO:0097440)
0.1 1.1 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 0.8 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.2 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 2.3 GO:0030137 COPI-coated vesicle(GO:0030137)
0.1 7.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 10.0 GO:0000922 spindle pole(GO:0000922)
0.1 0.6 GO:0070552 BRISC complex(GO:0070552)
0.1 1.2 GO:0000124 SAGA complex(GO:0000124)
0.1 0.4 GO:0042583 chromaffin granule(GO:0042583)
0.1 1.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 2.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.7 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 1.4 GO:0005682 U5 snRNP(GO:0005682)
0.1 2.5 GO:0035097 histone methyltransferase complex(GO:0035097)
0.1 0.3 GO:1990130 Iml1 complex(GO:1990130)
0.1 2.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 1.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.9 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 7.7 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.1 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 0.7 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0016600 flotillin complex(GO:0016600)
0.0 0.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 3.9 GO:0005795 Golgi stack(GO:0005795)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 5.3 GO:0034399 nuclear periphery(GO:0034399)
0.0 1.4 GO:0016235 aggresome(GO:0016235)
0.0 3.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 5.7 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 2.6 GO:0016605 PML body(GO:0016605)
0.0 2.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.5 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.9 GO:0000502 proteasome complex(GO:0000502)
0.0 2.5 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 2.1 GO:0072562 blood microparticle(GO:0072562)
0.0 1.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 1.2 GO:0016459 myosin complex(GO:0016459)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.7 GO:0005921 gap junction(GO:0005921)
0.0 0.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 3.2 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 4.0 GO:0000785 chromatin(GO:0000785)
0.0 4.7 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.5 GO:0008023 transcription elongation factor complex(GO:0008023)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
10.9 54.6 GO:0019976 interleukin-2 binding(GO:0019976)
7.1 28.4 GO:0031720 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
5.6 16.7 GO:0030492 hemoglobin binding(GO:0030492)
4.6 13.8 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
3.2 25.4 GO:0019863 IgE binding(GO:0019863)
2.8 25.4 GO:0070891 lipoteichoic acid binding(GO:0070891)
2.7 13.6 GO:0030369 ICAM-3 receptor activity(GO:0030369)
2.6 7.9 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
2.4 14.6 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
2.4 9.7 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
2.3 7.0 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
2.2 6.6 GO:0003692 left-handed Z-DNA binding(GO:0003692)
2.2 10.9 GO:0035478 chylomicron binding(GO:0035478)
2.0 16.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
2.0 5.9 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
1.9 5.8 GO:0042602 riboflavin reductase (NADPH) activity(GO:0042602)
1.9 5.6 GO:0036004 GAF domain binding(GO:0036004)
1.7 15.1 GO:0031849 olfactory receptor binding(GO:0031849)
1.6 8.2 GO:0004131 cytosine deaminase activity(GO:0004131)
1.5 11.8 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
1.3 26.8 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
1.3 9.3 GO:0019958 C-X-C chemokine binding(GO:0019958)
1.3 3.9 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
1.3 5.1 GO:0050436 microfibril binding(GO:0050436)
1.2 3.7 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
1.2 11.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
1.2 10.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
1.1 6.6 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
1.1 4.4 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
1.1 3.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
1.0 14.2 GO:0004016 adenylate cyclase activity(GO:0004016)
1.0 6.0 GO:0008384 IkappaB kinase activity(GO:0008384)
1.0 28.1 GO:0008009 chemokine activity(GO:0008009)
1.0 19.7 GO:0035325 Toll-like receptor binding(GO:0035325)
1.0 4.9 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.9 2.7 GO:0097677 STAT family protein binding(GO:0097677)
0.9 5.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.9 10.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.8 6.8 GO:0016803 ether hydrolase activity(GO:0016803)
0.8 5.9 GO:0030284 estrogen receptor activity(GO:0030284)
0.8 76.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.8 17.4 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.8 1.7 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.8 2.4 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.8 5.5 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.8 18.7 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.8 10.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.8 3.9 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.8 23.8 GO:0043274 phospholipase binding(GO:0043274)
0.8 4.5 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.7 3.6 GO:0001851 complement component C3b binding(GO:0001851)
0.7 1.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.7 13.7 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.7 9.9 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.7 2.0 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.7 2.6 GO:1990932 5.8S rRNA binding(GO:1990932)
0.6 1.9 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.6 1.3 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.6 2.6 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
0.6 5.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.6 5.9 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.6 2.4 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.6 2.3 GO:0051435 BH4 domain binding(GO:0051435)
0.6 3.9 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.5 3.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.5 6.5 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.5 4.8 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.5 12.2 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.5 1.6 GO:0004998 transferrin receptor activity(GO:0004998)
0.5 3.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.5 6.5 GO:1990405 protein antigen binding(GO:1990405)
0.5 2.0 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.5 3.4 GO:0046848 hydroxyapatite binding(GO:0046848)
0.5 2.4 GO:0030984 kininogen binding(GO:0030984)
0.5 5.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.5 2.9 GO:0008142 oxysterol binding(GO:0008142)
0.5 8.1 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.5 1.4 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.5 1.4 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.5 11.3 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.4 3.0 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.4 53.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.4 13.7 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.4 7.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.4 7.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.4 1.9 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.4 1.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.4 1.1 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.4 3.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.4 4.9 GO:0019865 immunoglobulin binding(GO:0019865)
0.4 12.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.4 21.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.4 1.4 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.4 4.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.3 18.3 GO:0050699 WW domain binding(GO:0050699)
0.3 59.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.3 5.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.3 5.7 GO:0008301 DNA binding, bending(GO:0008301)
0.3 3.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.3 1.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.3 1.2 GO:0030519 snoRNP binding(GO:0030519)
0.3 1.9 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.3 7.7 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.3 1.8 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.3 29.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.3 13.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.3 1.2 GO:0016882 cyclo-ligase activity(GO:0016882)
0.3 1.7 GO:0050786 RAGE receptor binding(GO:0050786)
0.3 4.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.3 8.5 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.3 3.4 GO:0051525 NFAT protein binding(GO:0051525)
0.3 3.0 GO:0043426 MRF binding(GO:0043426)
0.3 0.8 GO:0097100 supercoiled DNA binding(GO:0097100)
0.3 1.9 GO:0001849 complement component C1q binding(GO:0001849)
0.3 14.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.3 26.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.3 16.4 GO:0004601 peroxidase activity(GO:0004601)
0.3 1.5 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.3 1.0 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.2 6.8 GO:0071837 HMG box domain binding(GO:0071837)
0.2 0.7 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.2 4.3 GO:0015643 toxic substance binding(GO:0015643)
0.2 2.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.2 1.7 GO:0070404 NADH binding(GO:0070404)
0.2 10.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2 1.4 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.2 9.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 3.2 GO:0005522 profilin binding(GO:0005522)
0.2 5.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 1.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.2 1.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 2.9 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.2 0.7 GO:0098808 mRNA cap binding(GO:0098808)
0.2 0.6 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372)
0.2 1.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 36.7 GO:0001047 core promoter binding(GO:0001047)
0.2 1.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.2 5.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 4.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 6.9 GO:0042605 peptide antigen binding(GO:0042605)
0.2 0.7 GO:0038100 nodal binding(GO:0038100)
0.2 3.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.2 1.0 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.2 7.0 GO:0003785 actin monomer binding(GO:0003785)
0.2 15.5 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 0.9 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.4 GO:0004798 thymidylate kinase activity(GO:0004798)
0.1 0.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 16.5 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 5.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.1 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 29.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 2.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.6 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.1 1.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 2.4 GO:0070628 proteasome binding(GO:0070628)
0.1 4.5 GO:0032452 histone demethylase activity(GO:0032452)
0.1 2.0 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 2.6 GO:0003823 antigen binding(GO:0003823)
0.1 1.0 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 3.6 GO:0022829 wide pore channel activity(GO:0022829)
0.1 3.7 GO:0008198 ferrous iron binding(GO:0008198)
0.1 1.2 GO:0051434 BH3 domain binding(GO:0051434)
0.1 2.8 GO:0001618 virus receptor activity(GO:0001618)
0.1 1.5 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 1.9 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.1 2.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.3 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.1 1.3 GO:0051400 BH domain binding(GO:0051400)
0.1 1.9 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.5 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.1 1.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 1.4 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.4 GO:0045159 myosin II binding(GO:0045159)
0.1 3.7 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 5.1 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 4.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 3.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 2.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 2.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.5 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 7.6 GO:0019894 kinesin binding(GO:0019894)
0.1 0.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.9 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.9 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 1.4 GO:0042287 MHC protein binding(GO:0042287) MHC class I protein binding(GO:0042288)
0.1 0.5 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.1 4.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.6 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.1 0.2 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1 24.2 GO:0030246 carbohydrate binding(GO:0030246)
0.1 2.3 GO:0019843 rRNA binding(GO:0019843)
0.1 0.4 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.5 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 2.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 3.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.1 GO:0035375 zymogen binding(GO:0035375)
0.1 1.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.6 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 4.2 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 9.4 GO:0002020 protease binding(GO:0002020)
0.1 0.7 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.4 GO:0035197 siRNA binding(GO:0035197)
0.1 0.8 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 7.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 0.9 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 3.9 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.4 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 8.9 GO:0017124 SH3 domain binding(GO:0017124)
0.1 0.8 GO:0031432 titin binding(GO:0031432)
0.1 0.6 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 7.8 GO:0005178 integrin binding(GO:0005178)
0.1 0.3 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.3 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 0.3 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 0.7 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 0.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.8 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.9 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.5 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 9.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 5.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 3.7 GO:0005518 collagen binding(GO:0005518)
0.0 1.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 1.2 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.8 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 1.4 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 13.7 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.3 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 1.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.6 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.2 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 3.9 GO:0004519 endonuclease activity(GO:0004519)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 4.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.2 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 2.5 GO:0005550 pheromone binding(GO:0005550)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.5 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 2.2 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 1.4 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.4 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 1.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.6 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.0 GO:0001003 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 32.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
1.4 113.4 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
1.0 108.2 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
1.0 57.8 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.8 16.7 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.7 7.6 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.7 33.5 PID BCR 5PATHWAY BCR signaling pathway
0.6 15.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.5 22.9 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.5 23.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.5 24.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.4 20.8 PID ARF6 PATHWAY Arf6 signaling events
0.4 1.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.4 15.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.4 5.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.4 11.2 PID CD40 PATHWAY CD40/CD40L signaling
0.4 45.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.4 10.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.4 31.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.4 5.8 PID EPO PATHWAY EPO signaling pathway
0.3 13.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.3 7.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.3 6.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 2.8 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.2 13.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.2 14.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.2 7.0 ST ADRENERGIC Adrenergic Pathway
0.2 4.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 16.2 PID CMYB PATHWAY C-MYB transcription factor network
0.2 2.0 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.2 4.0 PID IFNG PATHWAY IFN-gamma pathway
0.2 11.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.2 5.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.2 5.2 PID IL4 2PATHWAY IL4-mediated signaling events
0.2 12.4 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 14.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 6.3 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.1 3.3 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 5.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 3.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 4.2 PID CONE PATHWAY Visual signal transduction: Cones
0.1 1.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 14.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 4.5 PID P53 REGULATION PATHWAY p53 pathway
0.1 2.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.1 1.7 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 0.5 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 0.8 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 1.2 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.3 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 1.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 2.1 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.0 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 2.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.8 PID E2F PATHWAY E2F transcription factor network
0.0 4.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 2.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 98.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
1.9 3.8 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
1.7 41.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
1.4 76.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
1.3 19.7 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
1.1 18.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
1.1 10.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
1.0 5.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
1.0 46.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
1.0 51.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
1.0 4.8 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.9 15.8 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.8 26.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.8 18.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.7 8.9 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.6 9.0 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.4 12.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.4 22.4 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.4 21.2 REACTOME G1 PHASE Genes involved in G1 Phase
0.4 13.1 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.3 9.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.3 8.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.3 3.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.3 4.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.3 4.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.3 6.0 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.3 9.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.3 10.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.3 3.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.3 20.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.3 2.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.3 13.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.2 6.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 10.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.2 5.5 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.2 13.0 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.2 13.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 2.8 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 8.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 2.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 1.8 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.2 3.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.2 2.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 2.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.2 4.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 5.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2 2.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.2 2.4 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 4.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 0.7 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 2.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 13.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 9.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 28.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.2 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.1 8.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 3.0 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 24.5 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.1 0.9 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.1 1.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 3.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.5 REACTOME G PROTEIN BETA GAMMA SIGNALLING Genes involved in G-protein beta:gamma signalling
0.1 8.6 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.1 1.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 3.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 4.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 0.5 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 3.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 2.1 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.1 3.8 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 2.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 0.3 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.1 0.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 6.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 9.5 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.1 0.7 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 0.8 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 2.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.3 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 2.7 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.1 2.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 1.3 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.1 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 2.4 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 2.3 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.3 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.8 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 1.4 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels