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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Scrt2

Z-value: 1.37

Motif logo

Transcription factors associated with Scrt2

Gene Symbol Gene ID Gene Info
ENSMUSG00000060257.3 Scrt2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Scrt2mm39_v1_chr2_+_151923449_1519235440.788.4e-16Click!

Activity profile of Scrt2 motif

Sorted Z-values of Scrt2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Scrt2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_+_66833434 19.73 ENSMUST00000031131.11
ubiquitin carboxy-terminal hydrolase L1
chr9_+_45281483 18.72 ENSMUST00000085939.8
ENSMUST00000217381.2
FXYD domain-containing ion transport regulator 6
chr1_-_79417732 15.17 ENSMUST00000185234.2
ENSMUST00000049972.6
secretogranin II
chr14_+_9646630 13.55 ENSMUST00000112658.8
ENSMUST00000112657.9
ENSMUST00000177814.2
ENSMUST00000067491.14
Ca2+-dependent secretion activator
chr2_-_148574353 13.16 ENSMUST00000028926.13
N-ethylmaleimide sensitive fusion protein attachment protein beta
chrX_+_151922936 12.38 ENSMUST00000039720.11
ENSMUST00000144175.3
Ras-related GTP binding B
chr11_-_100246209 12.24 ENSMUST00000146878.3
huntingtin-associated protein 1
chr5_+_37403098 12.22 ENSMUST00000031004.11
collapsin response mediator protein 1
chr9_+_58395850 11.18 ENSMUST00000085658.5
inhibitory synaptic factor 1
chr10_+_56253418 10.86 ENSMUST00000068581.9
ENSMUST00000217789.2
gap junction protein, alpha 1
chr13_+_97377604 10.65 ENSMUST00000041623.9
ectodermal-neural cortex 1
chr7_-_118047394 10.31 ENSMUST00000203796.4
ENSMUST00000203485.3
synaptotagmin XVII
chr8_-_4309257 10.12 ENSMUST00000053252.9
cortexin 1
chr11_+_103540391 10.10 ENSMUST00000057870.4
reprimo-like
chr5_+_118307754 9.84 ENSMUST00000054836.7
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr3_-_33197157 9.56 ENSMUST00000108226.8
peroxisomal biogenesis factor 5-like
chr10_-_79973210 9.18 ENSMUST00000170219.9
ENSMUST00000169546.9
calcium channel, voltage-dependent, beta subunit associated regulatory protein
chr3_+_129974531 9.12 ENSMUST00000080335.11
ENSMUST00000106353.2
collagen, type XXV, alpha 1
chr2_-_53975501 9.02 ENSMUST00000100089.3
reprimo, TP53 dependent G2 arrest mediator candidate
chr2_-_73605387 8.80 ENSMUST00000166199.9
chimerin 1
chr11_+_71640739 8.10 ENSMUST00000150531.2
WSC domain containing 1
chrX_+_5959507 7.81 ENSMUST00000103007.4
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr16_+_16888145 7.39 ENSMUST00000232574.2
yippee like 1
chr11_+_77384234 7.06 ENSMUST00000037285.10
ENSMUST00000100812.4
GIT ArfGAP 1
chrX_-_100128958 6.79 ENSMUST00000101362.8
ENSMUST00000073927.5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3
chr16_+_20514925 6.73 ENSMUST00000128273.2
family with sequence similarity 131, member A
chr14_+_55120777 6.26 ENSMUST00000022806.10
BCL2-like 2
chr8_+_31677345 6.22 ENSMUST00000066173.12
ENSMUST00000161788.8
ENSMUST00000110527.9
ENSMUST00000161502.2
fucosyltransferase 10
chr10_-_79449826 5.98 ENSMUST00000059699.9
ENSMUST00000178228.3
C2 calcium-dependent domain containing 4C
chr2_+_121188195 5.97 ENSMUST00000125812.8
ENSMUST00000078222.9
ENSMUST00000125221.3
ENSMUST00000150271.8
creatine kinase, mitochondrial 1, ubiquitous
chr6_-_23839136 5.94 ENSMUST00000166458.9
ENSMUST00000142913.9
ENSMUST00000069074.14
ENSMUST00000115361.9
ENSMUST00000018122.14
ENSMUST00000115356.3
Ca2+-dependent activator protein for secretion 2
chr16_+_16888084 5.94 ENSMUST00000231514.2
yippee like 1
chr6_-_53797748 5.89 ENSMUST00000127748.5
TLR4 interactor with leucine-rich repeats
chr11_-_55310724 5.87 ENSMUST00000108858.8
ENSMUST00000141530.2
secreted acidic cysteine rich glycoprotein
chr9_+_59563872 5.84 ENSMUST00000215623.2
ENSMUST00000215660.2
ENSMUST00000217353.2
pyruvate kinase, muscle
chr9_+_59563838 5.72 ENSMUST00000163694.4
pyruvate kinase, muscle
chr11_+_110956980 5.53 ENSMUST00000042970.3
potassium inwardly-rectifying channel, subfamily J, member 2
chr17_-_24752683 5.48 ENSMUST00000061764.14
RAB26, member RAS oncogene family
chr11_-_107805830 5.46 ENSMUST00000039071.3
calcium channel, voltage-dependent, gamma subunit 5
chr2_+_112097087 5.28 ENSMUST00000110987.9
ENSMUST00000028549.14
solute carrier family 12, member 6
chr10_-_109669053 5.22 ENSMUST00000238286.2
neuron navigator 3
chr10_+_116013256 5.12 ENSMUST00000155606.8
ENSMUST00000128399.2
protein tyrosine phosphatase, receptor type, R
chr14_+_119375753 5.05 ENSMUST00000065904.5
heparan sulfate 6-O-sulfotransferase 3
chr15_-_71599664 4.99 ENSMUST00000022953.10
family with sequence similarity 135, member B
chr15_+_34306812 4.96 ENSMUST00000226766.2
ENSMUST00000163455.9
ENSMUST00000022947.7
ENSMUST00000228570.2
ENSMUST00000227759.2
matrilin 2
chr12_-_11200306 4.85 ENSMUST00000055673.2
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
chr12_+_99930757 4.80 ENSMUST00000160413.8
ENSMUST00000177549.8
ENSMUST00000049788.9
potassium channel, subfamily K, member 13
chr18_-_46444941 4.72 ENSMUST00000072835.7
coiled-coil domain containing 112
chr15_+_6451721 4.65 ENSMUST00000163082.2
disabled 2, mitogen-responsive phosphoprotein
chr6_-_23839419 4.51 ENSMUST00000115358.9
ENSMUST00000163871.9
Ca2+-dependent activator protein for secretion 2
chr9_-_27066685 4.45 ENSMUST00000034472.16
junction adhesion molecule 3
chr8_-_85663976 4.36 ENSMUST00000109741.9
ENSMUST00000119820.2
microtubule associated serine/threonine kinase 1
chr3_-_122778052 4.26 ENSMUST00000199401.2
ENSMUST00000197314.5
ENSMUST00000197934.5
ENSMUST00000090379.7
ubiquitin specific peptidase 53
chr12_-_17374704 4.20 ENSMUST00000020884.16
ENSMUST00000095820.12
ENSMUST00000221129.2
ENSMUST00000127185.8
ATPase, H+ transporting, lysosomal V1 subunit C2
chr9_-_50650663 4.19 ENSMUST00000117093.2
ENSMUST00000121634.8
DIX domain containing 1
chr5_-_73805063 4.17 ENSMUST00000081170.9
sarcoglycan, beta (dystrophin-associated glycoprotein)
chr3_-_107993906 4.15 ENSMUST00000102638.8
ENSMUST00000102637.8
adenosine monophosphate deaminase 2
chr11_-_76514334 4.14 ENSMUST00000238684.2
active BCR-related gene
chr15_-_11907267 4.10 ENSMUST00000228489.2
natriuretic peptide receptor 3
chr14_+_55120875 4.08 ENSMUST00000134077.2
ENSMUST00000172844.8
ENSMUST00000133397.4
ENSMUST00000227108.2
predicted gene 20521
BCL2-like 2
chr6_-_85742726 4.00 ENSMUST00000050780.8
N-acetyltransferase 8 (GCN5-related) family member 3
chr4_-_119395966 3.95 ENSMUST00000079611.13
FSHD region gene 2 family member 1
chrX_-_56549092 3.91 ENSMUST00000057645.6
G protein-coupled receptor 101
chr13_-_98342659 3.90 ENSMUST00000109426.3
Rho guanine nucleotide exchange factor (GEF) 28
chr2_+_112096154 3.84 ENSMUST00000110991.9
solute carrier family 12, member 6
chr7_+_126446588 3.82 ENSMUST00000141805.8
ENSMUST00000064110.14
ENSMUST00000205938.2
ENSMUST00000152051.8
double C2, alpha
chr10_+_116013122 3.81 ENSMUST00000148731.8
protein tyrosine phosphatase, receptor type, R
chr4_-_45084564 3.78 ENSMUST00000052236.13
F-box protein 10
chr15_+_98532624 3.73 ENSMUST00000003442.9
calcium channel, voltage-dependent, beta 3 subunit
chr2_-_30014466 3.66 ENSMUST00000044751.14
zyg-11 related, cell cycle regulator
chr17_-_26063391 3.63 ENSMUST00000176591.8
ras homolog family member T2
chr17_-_26063488 3.62 ENSMUST00000176709.2
ras homolog family member T2
chr4_-_135221926 3.55 ENSMUST00000102549.10
NIPA-like domain containing 3
chr1_+_183078851 3.55 ENSMUST00000193625.2
axin interactor, dorsalization associated
chr16_+_44167484 3.54 ENSMUST00000050897.7
spindle and centriole associated protein 1
chr12_+_4642629 3.42 ENSMUST00000218402.2
intersectin 2
chr6_-_90693471 3.40 ENSMUST00000101153.10
IQ motif and Sec7 domain 1
chr8_-_103512274 3.37 ENSMUST00000075190.5
cadherin 11
chr18_-_3281752 3.34 ENSMUST00000140332.8
ENSMUST00000147138.8
cAMP responsive element modulator
chr2_-_126625343 3.17 ENSMUST00000028842.9
ENSMUST00000130356.3
ubiquitin specific peptidase 50
chr4_-_151129020 3.15 ENSMUST00000103204.11
period circadian clock 3
chr3_+_37402795 3.13 ENSMUST00000200585.5
ENSMUST00000038885.10
fibroblast growth factor 2
chr4_-_135221810 3.08 ENSMUST00000105856.9
NIPA-like domain containing 3
chr2_-_30720345 2.90 ENSMUST00000041726.4
ankyrin repeat and SOCS box-containing 6
chr15_-_78602971 2.85 ENSMUST00000088592.6
leucine rich repeat and fibronectin type III, extracellular 2
chr7_-_24211879 2.84 ENSMUST00000234781.2
predicted gene, 50092
chr7_+_122977205 2.71 ENSMUST00000033025.7
ENSMUST00000206574.2
leucine carboxyl methyltransferase 1
chr7_-_127805518 2.57 ENSMUST00000033049.9
cytochrome c oxidase subunit 6A2
chr18_+_36693024 2.44 ENSMUST00000134146.8
ankyrin repeat and KH domain containing 1
chr16_+_16887991 2.41 ENSMUST00000232258.2
yippee like 1
chr19_-_56996617 2.32 ENSMUST00000118800.8
ENSMUST00000111584.9
ENSMUST00000122359.8
ENSMUST00000148049.8
actin filament associated protein 1-like 2
chr16_+_3702493 2.30 ENSMUST00000176233.2
predicted gene 20695
chr2_+_31840151 2.30 ENSMUST00000001920.13
ENSMUST00000151276.3
allograft inflammatory factor 1-like
chr19_+_47167554 2.28 ENSMUST00000235290.2
neuralized E3 ubiquitin protein ligase 1A
chr11_-_58346806 2.19 ENSMUST00000055204.6
olfactory receptor 30
chrX_-_48877080 2.11 ENSMUST00000114893.8
immunoglobulin superfamily, member 1
chr3_-_57209357 2.00 ENSMUST00000196979.5
ENSMUST00000029376.13
transmembrane 4 superfamily member 1
chr18_-_3281089 1.98 ENSMUST00000139537.2
ENSMUST00000124747.8
cAMP responsive element modulator
chr11_+_87483723 1.78 ENSMUST00000119628.8
myotubularin related protein 4
chr2_+_91087156 1.71 ENSMUST00000144394.8
ENSMUST00000028694.12
ENSMUST00000168916.8
ENSMUST00000156919.8
protein kinase C and casein kinase substrate in neurons 3
chr5_-_123822351 1.60 ENSMUST00000111564.8
ENSMUST00000063905.12
CAP-GLY domain containing linker protein 1
chr18_-_70186503 1.58 ENSMUST00000117692.8
ENSMUST00000069749.9
RAB27B, member RAS oncogene family
chr12_+_4642987 1.57 ENSMUST00000062580.8
ENSMUST00000220311.2
intersectin 2
chr7_-_130931235 1.43 ENSMUST00000188899.2
family with sequence similarity 24 member B
chr17_-_40519480 1.41 ENSMUST00000033585.7
phosphoglycerate kinase 2
chr5_-_137609691 1.33 ENSMUST00000031731.14
procollagen C-endopeptidase enhancer protein
chr5_-_137609634 1.32 ENSMUST00000054564.13
procollagen C-endopeptidase enhancer protein
chr12_+_105302853 1.26 ENSMUST00000180458.9
Tcl1 upstream neural differentiation associated RNA
chr5_-_123822338 1.17 ENSMUST00000111561.8
CAP-GLY domain containing linker protein 1
chr19_-_61216834 1.14 ENSMUST00000076046.7
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr9_-_21763898 1.12 ENSMUST00000217336.2
ENSMUST00000034728.9
dedicator of cytokinesis 6
chr19_+_4889394 1.12 ENSMUST00000088653.3
coiled-coil domain containing 87
chr7_+_106969950 1.11 ENSMUST00000073459.12
synaptotagmin IX
chr7_-_119078472 1.08 ENSMUST00000209095.2
ENSMUST00000033263.6
ENSMUST00000207261.2
uromodulin
chr6_-_57885013 1.01 ENSMUST00000228076.2
ENSMUST00000228905.2
ENSMUST00000227650.2
ENSMUST00000227342.2
ENSMUST00000228257.2
vomeronasal 1 receptor 22
chr10_-_129023288 0.98 ENSMUST00000072976.4
olfactory receptor 773
chr18_-_3281727 0.97 ENSMUST00000154705.8
ENSMUST00000151084.8
cAMP responsive element modulator
chr3_-_124219673 0.90 ENSMUST00000029598.10
RIKEN cDNA 1700006A11 gene
chr7_-_119078330 0.86 ENSMUST00000207460.2
uromodulin
chrX_-_151552457 0.85 ENSMUST00000101141.9
ENSMUST00000062317.5
shroom family member 2
chr18_-_3280999 0.84 ENSMUST00000049942.13
cAMP responsive element modulator
chr7_-_127545896 0.80 ENSMUST00000118755.8
ENSMUST00000094026.10
protease, serine 36
chr7_-_134539993 0.76 ENSMUST00000171394.3
inhibitory synaptic factor 2A
chr18_+_60880149 0.75 ENSMUST00000236652.2
ENSMUST00000235966.2
ribosomal protein S14
chr5_-_138169476 0.72 ENSMUST00000147920.2
minichromosome maintenance complex component 7
chr10_-_19727165 0.69 ENSMUST00000059805.6
solute carrier family 35, member D3
chr7_-_29898236 0.66 ENSMUST00000001845.13
calpain, small subunit 1
chr16_+_3702604 0.62 ENSMUST00000115860.8
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr1_-_24139387 0.53 ENSMUST00000027337.15
family with sequence similarity 135, member A
chr9_+_91250864 0.51 ENSMUST00000173054.8
zinc finger protein of the cerebellum 4
chrX_+_84091915 0.48 ENSMUST00000239019.2
ENSMUST00000113992.3
ENSMUST00000113991.8
dystrophin, muscular dystrophy
chr16_+_3702523 0.41 ENSMUST00000176625.8
ENSMUST00000186375.8
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr3_-_20209220 0.39 ENSMUST00000184552.2
glycogenin
chr14_+_31750946 0.39 ENSMUST00000022460.11
polypeptide N-acetylgalactosaminyltransferase 15
chr7_+_99659121 0.38 ENSMUST00000107084.8
chordin-like 2
chr13_-_81781238 0.36 ENSMUST00000126444.8
ENSMUST00000128585.9
ENSMUST00000146749.2
ENSMUST00000095585.11
adhesion G protein-coupled receptor V1
chr1_-_24139263 0.33 ENSMUST00000187369.7
ENSMUST00000187752.7
ENSMUST00000186999.7
family with sequence similarity 135, member A
chr10_+_116137277 0.28 ENSMUST00000092167.7
protein tyrosine phosphatase, receptor type, B
chr12_-_40087393 0.25 ENSMUST00000146905.2
ADP-ribosylation factor-like 4A
chr8_+_77628916 0.18 ENSMUST00000109912.8
ENSMUST00000128862.2
ENSMUST00000109911.8
nuclear receptor subfamily 3, group C, member 2
chr7_+_126447080 0.15 ENSMUST00000147257.2
ENSMUST00000139174.2
double C2, alpha
chr4_-_41731142 0.13 ENSMUST00000171251.8
AT rich interactive domain 3C (BRIGHT-like)
chr9_-_22028370 0.12 ENSMUST00000213233.2
ELF1 homolog, elongation factor 1
chr2_-_168432111 0.11 ENSMUST00000029057.13
ENSMUST00000074618.10
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
chr10_+_26105605 0.09 ENSMUST00000218301.2
ENSMUST00000164660.8
ENSMUST00000060716.6
sterile alpha motif domain containing 3
chr7_+_100742070 0.07 ENSMUST00000208439.2
FCH and double SH3 domains 2
chr5_+_89675288 0.02 ENSMUST00000048557.3
neuropeptide FF receptor 2
chr10_+_56253531 0.02 ENSMUST00000220194.2
ENSMUST00000218834.2
gap junction protein, alpha 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 24.0 GO:1990504 dense core granule exocytosis(GO:1990504)
3.6 10.9 GO:0010232 vascular transport(GO:0010232) milk ejection(GO:0060156)
3.3 19.7 GO:0007412 axon target recognition(GO:0007412)
3.1 12.2 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
2.4 12.2 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
2.3 9.1 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
1.8 5.5 GO:0090076 relaxation of skeletal muscle(GO:0090076)
1.8 10.7 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
1.7 5.0 GO:0031104 dendrite regeneration(GO:0031104)
1.6 9.8 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
1.6 3.1 GO:0021762 substantia nigra development(GO:0021762)
1.5 8.9 GO:0038128 ERBB2 signaling pathway(GO:0038128)
1.5 13.2 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
1.2 9.6 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
1.2 11.6 GO:0042866 pyruvate biosynthetic process(GO:0042866)
1.1 9.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
1.1 6.8 GO:0015819 lysine transport(GO:0015819)
1.1 12.4 GO:1990253 cellular response to leucine starvation(GO:1990253)
1.1 7.8 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
1.0 10.3 GO:0060011 Sertoli cell proliferation(GO:0060011)
1.0 15.2 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.9 4.7 GO:0035026 leading edge cell differentiation(GO:0035026)
0.9 3.5 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.8 5.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.6 2.8 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.5 2.7 GO:0006481 C-terminal protein methylation(GO:0006481)
0.5 4.1 GO:0060313 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.5 1.9 GO:0072218 ascending thin limb development(GO:0072021) thick ascending limb development(GO:0072023) metanephric ascending thin limb development(GO:0072218) metanephric thick ascending limb development(GO:0072233)
0.4 9.2 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.4 4.1 GO:0032264 IMP salvage(GO:0032264)
0.4 4.1 GO:0002158 osteoclast proliferation(GO:0002158)
0.4 15.3 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.4 6.6 GO:0015693 magnesium ion transport(GO:0015693)
0.3 4.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.3 4.4 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.3 7.2 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.3 10.5 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.3 4.2 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.2 3.7 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.2 3.9 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.2 4.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 0.7 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.2 6.2 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.2 19.2 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.2 2.3 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.2 3.4 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.2 8.8 GO:0008045 motor neuron axon guidance(GO:0008045)
0.2 2.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 3.9 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.1 5.5 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 5.5 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 4.3 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 5.9 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.1 1.0 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 4.2 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.1 5.9 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.1 7.1 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.1 2.3 GO:0046599 regulation of centriole replication(GO:0046599)
0.1 2.4 GO:0032401 establishment of melanosome localization(GO:0032401)
0.1 3.2 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.1 4.0 GO:0003401 axis elongation(GO:0003401)
0.1 2.3 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.1 1.1 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.1 1.0 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 3.7 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.1 6.0 GO:0032091 negative regulation of protein binding(GO:0032091)
0.1 1.3 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.2 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
0.0 0.4 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 2.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 4.6 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 3.8 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 2.6 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 1.4 GO:0006096 glycolytic process(GO:0006096)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 11.6 GO:1902912 pyruvate kinase complex(GO:1902912)
2.5 12.4 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
2.2 13.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
1.5 5.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
1.3 26.9 GO:0031045 dense core granule(GO:0031045)
1.2 9.6 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
1.1 4.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.9 4.7 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.8 10.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.7 5.9 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.5 10.9 GO:0005916 fascia adherens(GO:0005916)
0.5 4.4 GO:0033010 paranodal junction(GO:0033010)
0.3 3.0 GO:0016012 sarcoglycan complex(GO:0016012)
0.3 2.8 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.2 3.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 3.7 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.2 7.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.2 1.6 GO:0032585 multivesicular body membrane(GO:0032585)
0.2 13.1 GO:0031941 filamentous actin(GO:0031941)
0.1 2.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 5.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 10.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 12.2 GO:0005776 autophagosome(GO:0005776)
0.1 5.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.4 GO:0002142 stereocilia ankle link complex(GO:0002142) USH2 complex(GO:1990696)
0.1 22.2 GO:0044306 neuron projection terminus(GO:0044306)
0.1 5.4 GO:0042734 presynaptic membrane(GO:0042734)
0.1 2.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 6.3 GO:0005581 collagen trimer(GO:0005581)
0.1 2.3 GO:0097440 apical dendrite(GO:0097440)
0.0 1.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 4.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 10.9 GO:0005802 trans-Golgi network(GO:0005802)
0.0 6.0 GO:0043204 perikaryon(GO:0043204)
0.0 3.0 GO:0030667 secretory granule membrane(GO:0030667)
0.0 9.2 GO:0030426 growth cone(GO:0030426)
0.0 3.2 GO:0005604 basement membrane(GO:0005604)
0.0 3.5 GO:0005814 centriole(GO:0005814)
0.0 9.1 GO:0030424 axon(GO:0030424)
0.0 4.0 GO:0070382 exocytic vesicle(GO:0070382)
0.0 28.2 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 1.5 GO:0000922 spindle pole(GO:0000922)
0.0 6.7 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 7.0 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 19.7 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
2.6 13.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
2.3 11.6 GO:0004743 pyruvate kinase activity(GO:0004743)
2.3 9.1 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
1.8 5.5 GO:0019002 GMP binding(GO:0019002)
1.6 9.6 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
1.6 10.9 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
1.4 6.8 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
1.3 5.0 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
1.1 7.8 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
1.0 6.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.9 12.2 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.9 6.0 GO:0004111 creatine kinase activity(GO:0004111)
0.7 4.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.6 2.3 GO:0045183 translation factor activity, non-nucleic acid binding(GO:0045183)
0.5 2.7 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.4 18.3 GO:0042056 chemoattractant activity(GO:0042056)
0.4 12.2 GO:0031005 filamin binding(GO:0031005)
0.4 4.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.4 10.3 GO:0051400 BH domain binding(GO:0051400)
0.4 1.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.4 5.5 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.4 3.9 GO:0004935 adrenergic receptor activity(GO:0004935)
0.3 6.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.3 1.4 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.2 2.1 GO:0034711 inhibin binding(GO:0034711)
0.2 4.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 18.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 4.7 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 4.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 16.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 13.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.2 5.9 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.2 5.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.2 1.9 GO:0019864 IgG binding(GO:0019864)
0.1 3.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 5.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 9.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 8.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 8.1 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 2.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 2.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 4.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 2.6 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 8.5 GO:0005518 collagen binding(GO:0005518)
0.1 13.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 3.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.7 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 11.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 1.0 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.7 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.2 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.1 1.6 GO:0031489 myosin V binding(GO:0031489)
0.1 4.9 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 19.9 GO:0003924 GTPase activity(GO:0003924)
0.1 2.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 9.0 GO:0044325 ion channel binding(GO:0044325)
0.0 0.5 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 5.9 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 4.4 GO:0005178 integrin binding(GO:0005178)
0.0 5.5 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 2.2 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 19.7 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.2 10.5 PID ARF6 PATHWAY Arf6 signaling events
0.2 10.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 14.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 15.1 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 5.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 4.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 6.3 NABA COLLAGENS Genes encoding collagen proteins
0.1 6.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 4.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 3.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 10.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 13.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 4.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 4.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 15.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.5 12.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.3 4.8 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 3.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.2 4.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 3.1 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 9.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 4.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 1.8 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 6.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 5.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 4.9 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1 3.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 8.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 20.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 4.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 2.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.1 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex