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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Smad3

Z-value: 0.61

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Transcription factors associated with Smad3

Gene Symbol Gene ID Gene Info
Smad3
ENSMUSG00000032402.13 Smad3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Smad3mm39_v1_chr9_-_63665216_636652760.281.6e-02Click!

Activity profile of Smad3 motif

Sorted Z-values of Smad3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Smad3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr15_+_81820954 5.31 ENSMUST00000038757.8
ENSMUST00000230633.2
Csdc2
cold shock domain containing C2, RNA binding
chr15_-_76906832 3.85 ENSMUST00000019037.10
ENSMUST00000169226.9
Mb
myoglobin
chr7_-_119078472 2.39 ENSMUST00000209095.2
ENSMUST00000033263.6
ENSMUST00000207261.2
Umod
uromodulin
chr2_-_17465410 2.24 ENSMUST00000145492.2
Nebl
nebulette
chr13_+_23715220 2.08 ENSMUST00000102972.6
H4c8
H4 clustered histone 8
chr14_-_50020788 1.97 ENSMUST00000118129.2
ENSMUST00000036972.14
Armh4
armadillo-like helical domain containing 4
chr3_+_102641822 1.96 ENSMUST00000029451.12
Tspan2
tetraspanin 2
chr7_-_119078330 1.94 ENSMUST00000207460.2
Umod
uromodulin
chr17_-_43003135 1.89 ENSMUST00000170723.8
ENSMUST00000164524.2
ENSMUST00000024711.11
ENSMUST00000167993.8
Adgrf4
adhesion G protein-coupled receptor F4
chr1_-_75187417 1.81 ENSMUST00000113623.8
Glb1l
galactosidase, beta 1-like
chr5_+_96989853 1.80 ENSMUST00000196126.2
Anxa3
annexin A3
chr2_-_148250024 1.70 ENSMUST00000099270.5
Thbd
thrombomodulin
chr9_-_66421868 1.68 ENSMUST00000056890.10
Fbxl22
F-box and leucine-rich repeat protein 22
chr7_-_81104423 1.64 ENSMUST00000178892.3
ENSMUST00000098331.10
Cpeb1
cytoplasmic polyadenylation element binding protein 1
chr1_-_74076279 1.52 ENSMUST00000187281.7
Tns1
tensin 1
chr1_-_75187441 1.43 ENSMUST00000185448.2
Glb1l
galactosidase, beta 1-like
chr17_+_43671314 1.36 ENSMUST00000226087.2
Adgrf5
adhesion G protein-coupled receptor F5
chr2_-_173117936 1.36 ENSMUST00000139306.2
Pmepa1
prostate transmembrane protein, androgen induced 1
chr13_+_30844025 1.34 ENSMUST00000110310.9
ENSMUST00000095914.7
Dusp22
dual specificity phosphatase 22
chr14_+_31750946 1.22 ENSMUST00000022460.11
Galnt15
polypeptide N-acetylgalactosaminyltransferase 15
chr7_+_18910340 1.17 ENSMUST00000117338.8
Eml2
echinoderm microtubule associated protein like 2
chr15_-_58695379 1.16 ENSMUST00000072113.6
Tmem65
transmembrane protein 65
chr11_-_102338473 1.11 ENSMUST00000049057.5
Fam171a2
family with sequence similarity 171, member A2
chr15_-_81581457 0.97 ENSMUST00000072910.6
Chadl
chondroadherin-like
chr1_+_171197660 0.91 ENSMUST00000111286.9
Nectin4
nectin cell adhesion molecule 4
chr7_-_34914675 0.91 ENSMUST00000118444.3
ENSMUST00000122409.8
Lrp3
low density lipoprotein receptor-related protein 3
chr18_+_68066328 0.91 ENSMUST00000063775.5
Ldlrad4
low density lipoprotein receptor class A domain containing 4
chr19_-_47907705 0.90 ENSMUST00000095998.7
Itprip
inositol 1,4,5-triphosphate receptor interacting protein
chr4_+_57782150 0.89 ENSMUST00000124581.2
Pakap
paralemmin A kinase anchor protein
chr17_-_10538253 0.89 ENSMUST00000233828.2
ENSMUST00000233645.2
ENSMUST00000042296.9
Qk
quaking, KH domain containing RNA binding
chr5_+_92540444 0.87 ENSMUST00000126281.8
Art3
ADP-ribosyltransferase 3
chr5_-_72661546 0.86 ENSMUST00000005352.10
Corin
corin, serine peptidase
chr7_+_51530060 0.85 ENSMUST00000145049.2
Gas2
growth arrest specific 2
chr3_-_79645101 0.79 ENSMUST00000078527.13
Rxfp1
relaxin/insulin-like family peptide receptor 1
chr5_+_72360631 0.78 ENSMUST00000169617.3
Atp10d
ATPase, class V, type 10D
chr2_-_152673585 0.77 ENSMUST00000156688.2
ENSMUST00000007803.12
Bcl2l1
BCL2-like 1
chr1_+_172168764 0.73 ENSMUST00000056136.4
Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
chr15_+_81821112 0.71 ENSMUST00000135663.2
Csdc2
cold shock domain containing C2, RNA binding
chr13_+_23755551 0.71 ENSMUST00000079251.8
H2bc8
H2B clustered histone 8
chr12_+_58258558 0.70 ENSMUST00000110671.3
ENSMUST00000044299.3
Sstr1
somatostatin receptor 1
chr2_+_29759495 0.68 ENSMUST00000047521.7
ENSMUST00000134152.2
Cercam
cerebral endothelial cell adhesion molecule
chr13_-_23867924 0.64 ENSMUST00000171127.4
H2ac6
H2A clustered histone 6
chr13_+_22017906 0.63 ENSMUST00000180288.2
H2bc24
H2B clustered histone 24
chr9_+_21108001 0.63 ENSMUST00000003395.10
Pde4a
phosphodiesterase 4A, cAMP specific
chr11_+_69047815 0.62 ENSMUST00000036424.3
Alox12b
arachidonate 12-lipoxygenase, 12R type
chr2_+_157209506 0.60 ENSMUST00000081202.6
Manbal
mannosidase, beta A, lysosomal-like
chrX_+_142447361 0.59 ENSMUST00000126592.8
ENSMUST00000156449.8
ENSMUST00000155215.8
ENSMUST00000112865.8
Pak3
p21 (RAC1) activated kinase 3
chr6_+_129510117 0.59 ENSMUST00000032264.9
Gabarapl1
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr17_-_71575584 0.59 ENSMUST00000233148.2
Emilin2
elastin microfibril interfacer 2
chr11_-_94932158 0.59 ENSMUST00000038431.8
Pdk2
pyruvate dehydrogenase kinase, isoenzyme 2
chr13_+_23868175 0.58 ENSMUST00000018246.6
H2bc4
H2B clustered histone 4
chr3_+_92281215 0.57 ENSMUST00000056590.6
Sprr2g
small proline-rich protein 2G
chr7_-_4550523 0.56 ENSMUST00000206023.2
Syt5
synaptotagmin V
chrX_+_142447286 0.54 ENSMUST00000112868.8
Pak3
p21 (RAC1) activated kinase 3
chr7_-_127187767 0.53 ENSMUST00000072155.5
Ccdc189
coiled-coil domain containing 189
chr9_-_60595401 0.53 ENSMUST00000114034.9
ENSMUST00000065603.12
Lrrc49
leucine rich repeat containing 49
chrX_+_152615221 0.53 ENSMUST00000148708.2
ENSMUST00000123264.2
ENSMUST00000049999.9
Spin2c
spindlin family, member 2C
chr6_-_131664458 0.52 ENSMUST00000053652.6
Tas2r105
taste receptor, type 2, member 105
chr1_+_171077984 0.52 ENSMUST00000111315.9
ENSMUST00000219033.2
Adamts4
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4
chr8_-_85549452 0.52 ENSMUST00000065539.6
Dand5
DAN domain family member 5, BMP antagonist
chr2_+_3115250 0.50 ENSMUST00000072955.12
Fam171a1
family with sequence similarity 171, member A1
chr14_-_26693189 0.50 ENSMUST00000036570.5
Appl1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr9_+_43983493 0.49 ENSMUST00000176671.2
Usp2
ubiquitin specific peptidase 2
chr18_+_65156620 0.49 ENSMUST00000080418.7
ENSMUST00000237854.2
Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr13_-_22225527 0.48 ENSMUST00000102977.4
H4c9
H4 clustered histone 9
chr14_-_55950545 0.48 ENSMUST00000002389.9
ENSMUST00000226907.2
Tgm1
transglutaminase 1, K polypeptide
chr7_-_12770556 0.45 ENSMUST00000123541.2
Ube2m
ubiquitin-conjugating enzyme E2M
chr11_-_58434332 0.43 ENSMUST00000108823.3
Olfr329
olfactory receptor 329
chr9_-_106533279 0.41 ENSMUST00000023959.13
ENSMUST00000201681.2
Grm2
glutamate receptor, metabotropic 2
chr5_-_53864874 0.41 ENSMUST00000031093.5
Cckar
cholecystokinin A receptor
chr13_-_21934675 0.40 ENSMUST00000102983.2
H4c12
H4 clustered histone 12
chr13_-_23420117 0.39 ENSMUST00000235574.2
ENSMUST00000226672.3
Vmn1r222
vomeronasal 1 receptor 222
chr1_+_146373352 0.37 ENSMUST00000132847.8
ENSMUST00000166814.8
Brinp3
bone morphogenetic protein/retinoic acid inducible neural specific 3
chr4_+_102427247 0.37 ENSMUST00000097950.9
Pde4b
phosphodiesterase 4B, cAMP specific
chr7_-_24016020 0.37 ENSMUST00000108436.8
ENSMUST00000032673.15
Zfp94
zinc finger protein 94
chr1_+_131616407 0.36 ENSMUST00000064679.9
ENSMUST00000064664.10
ENSMUST00000136247.8
Rab7b
RAB7B, member RAS oncogene family
chr10_-_12424623 0.35 ENSMUST00000219003.2
Utrn
utrophin
chr13_+_22227359 0.35 ENSMUST00000110452.2
H2bc11
H2B clustered histone 11
chr4_+_150171822 0.35 ENSMUST00000094451.4
Gpr157
G protein-coupled receptor 157
chr4_+_45018583 0.35 ENSMUST00000133157.8
ENSMUST00000029999.15
ENSMUST00000107814.10
Polr1e
polymerase (RNA) I polypeptide E
chr8_-_13727575 0.34 ENSMUST00000117551.4
Rasa3
RAS p21 protein activator 3
chr2_+_177834868 0.34 ENSMUST00000103065.2
Phactr3
phosphatase and actin regulator 3
chr1_+_107456731 0.33 ENSMUST00000182198.8
Serpinb10
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10
chr16_-_15412371 0.32 ENSMUST00000115776.2
ENSMUST00000115777.10
Ube2v2
ubiquitin-conjugating enzyme E2 variant 2
chr1_-_185061525 0.32 ENSMUST00000027921.11
ENSMUST00000110975.8
ENSMUST00000110974.4
Iars2
isoleucine-tRNA synthetase 2, mitochondrial
chr6_+_136785230 0.32 ENSMUST00000074556.7
ENSMUST00000203982.2
H2aj
H2J.A histone
chr5_+_75735576 0.32 ENSMUST00000144270.8
ENSMUST00000005815.7
Kit
KIT proto-oncogene receptor tyrosine kinase
chr6_+_120070307 0.32 ENSMUST00000112711.9
Ninj2
ninjurin 2
chrX_-_143471176 0.31 ENSMUST00000040184.4
Trpc5
transient receptor potential cation channel, subfamily C, member 5
chrX_+_72454702 0.31 ENSMUST00000033740.12
Zfp92
zinc finger protein 92
chr3_-_96170627 0.30 ENSMUST00000171473.3
H4c14
H4 clustered histone 14
chr14_+_64331130 0.30 ENSMUST00000224112.2
ENSMUST00000165710.2
ENSMUST00000170709.2
Prss51
protease, serine 51
chrX_-_94070277 0.28 ENSMUST00000096367.5
Spin4
spindlin family, member 4
chr7_-_43885522 0.28 ENSMUST00000206686.2
ENSMUST00000037220.5
1700028J19Rik
RIKEN cDNA 1700028J19 gene
chr13_+_23718038 0.27 ENSMUST00000073261.3
H2ac10
H2A clustered histone 10
chr4_-_88562696 0.27 ENSMUST00000105149.3
Ifna13
interferon alpha 13
chr13_+_22220000 0.27 ENSMUST00000110455.4
H2bc12
H2B clustered histone 12
chr18_+_60659257 0.26 ENSMUST00000223984.2
ENSMUST00000025505.7
ENSMUST00000223590.2
Dctn4
dynactin 4
chr4_+_151174027 0.26 ENSMUST00000105667.3
Gm13090
predicted gene 13090
chr11_-_79145489 0.26 ENSMUST00000017821.12
Wsb1
WD repeat and SOCS box-containing 1
chr4_-_129015493 0.26 ENSMUST00000135763.2
ENSMUST00000149763.3
ENSMUST00000164649.8
Hpca
hippocalcin
chr3_+_107008343 0.26 ENSMUST00000197470.5
Kcna2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr13_+_23765546 0.26 ENSMUST00000102968.3
H4c4
H4 clustered histone 4
chr5_+_136067350 0.25 ENSMUST00000062606.8
Upk3b
uroplakin 3B
chr1_-_23948764 0.25 ENSMUST00000129254.8
Smap1
small ArfGAP 1
chr2_-_164876690 0.24 ENSMUST00000122070.2
ENSMUST00000121377.8
ENSMUST00000153905.2
ENSMUST00000040381.15
Ncoa5
nuclear receptor coactivator 5
chr12_-_114370581 0.24 ENSMUST00000191918.2
Ighv6-4
immunoglobulin heavy variable V6-4
chr16_-_15412336 0.24 ENSMUST00000118236.8
ENSMUST00000096234.4
Ube2v2
ubiquitin-conjugating enzyme E2 variant 2
chr1_-_144427302 0.23 ENSMUST00000184189.3
Rgs21
regulator of G-protein signalling 21
chr13_+_22268610 0.22 ENSMUST00000228243.2
ENSMUST00000226680.2
Vmn1r188
vomeronasal 1 receptor 188
chr12_-_115129697 0.21 ENSMUST00000103524.2
ENSMUST00000193145.2
Ighv8-6
immunoglobulin heavy variable V8-6
chr4_+_95445731 0.20 ENSMUST00000079223.11
ENSMUST00000177394.8
Fggy
FGGY carbohydrate kinase domain containing
chr11_-_99877423 0.20 ENSMUST00000105050.4
Krtap16-1
keratin associated protein 16-1
chr6_+_90105406 0.20 ENSMUST00000072859.6
Vmn1r51
vomeronasal 1 receptor 51
chr7_+_104506216 0.19 ENSMUST00000067695.8
Usp17la
ubiquitin specific peptidase 17-like A
chr2_-_132787790 0.19 ENSMUST00000038280.5
Fermt1
fermitin family member 1
chr2_-_30084124 0.18 ENSMUST00000113659.8
ENSMUST00000113660.2
Kyat1
kynurenine aminotransferase 1
chr7_+_127187910 0.17 ENSMUST00000205694.2
ENSMUST00000033088.8
ENSMUST00000206914.2
Rnf40
ring finger protein 40
chr10_+_129336682 0.17 ENSMUST00000056002.5
ENSMUST00000218901.2
Olfr790
olfactory receptor 790
chr18_-_77134939 0.16 ENSMUST00000137354.8
ENSMUST00000137498.8
Katnal2
katanin p60 subunit A-like 2
chr13_+_23940964 0.16 ENSMUST00000102965.4
H4c2
H4 clustered histone 2
chr6_+_21985902 0.16 ENSMUST00000115383.9
Cped1
cadherin-like and PC-esterase domain containing 1
chr17_-_37404764 0.16 ENSMUST00000087144.5
Olfr91
olfactory receptor 91
chr13_-_22289994 0.15 ENSMUST00000227357.2
ENSMUST00000228428.2
Vmn1r189
vomeronasal 1 receptor 189
chr18_-_77134980 0.14 ENSMUST00000154665.2
ENSMUST00000026486.13
ENSMUST00000123650.2
ENSMUST00000126153.8
Katnal2
katanin p60 subunit A-like 2
chr4_+_150366028 0.14 ENSMUST00000105682.9
Rere
arginine glutamic acid dipeptide (RE) repeats
chr9_-_123778334 0.14 ENSMUST00000071404.5
Ccr1l1
chemokine (C-C motif) receptor 1-like 1
chr1_+_131616504 0.14 ENSMUST00000129905.2
Rab7b
RAB7B, member RAS oncogene family
chr11_-_87719115 0.13 ENSMUST00000136446.3
Lpo
lactoperoxidase
chr9_+_53678801 0.13 ENSMUST00000048670.10
Slc35f2
solute carrier family 35, member F2
chr12_+_100745333 0.13 ENSMUST00000110073.8
ENSMUST00000110069.8
Dglucy
D-glutamate cyclase
chr15_-_101471324 0.12 ENSMUST00000023714.5
Krt90
keratin 90
chr10_+_33780993 0.12 ENSMUST00000169670.8
Rsph4a
radial spoke head 4 homolog A (Chlamydomonas)
chr3_-_27764522 0.12 ENSMUST00000195008.6
Fndc3b
fibronectin type III domain containing 3B
chr7_-_33713292 0.12 ENSMUST00000185399.2
ENSMUST00000085620.9
Scgb2b27
secretoglobin, family 2B, member 27
chr12_+_114594300 0.12 ENSMUST00000095364.3
ENSMUSG00000090765.2

chr12_+_119909692 0.09 ENSMUST00000058644.15
Tmem196
transmembrane protein 196
chr1_-_130839178 0.09 ENSMUST00000027673.11
Il20
interleukin 20
chr12_+_100745314 0.08 ENSMUST00000069782.11
Dglucy
D-glutamate cyclase
chr7_-_100613579 0.08 ENSMUST00000060174.6
P2ry6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr13_+_21971631 0.07 ENSMUST00000110473.3
ENSMUST00000102982.2
H2bc22
H2B clustered histone 22
chr13_-_23015518 0.07 ENSMUST00000226294.2
ENSMUST00000226180.2
Vmn1r210
vomeronasal 1 receptor 210
chr13_-_22017677 0.07 ENSMUST00000081342.7
H2ac24
H2A clustered histone 24
chr2_-_90301592 0.07 ENSMUST00000111493.8
Ptprj
protein tyrosine phosphatase, receptor type, J
chr13_-_21971388 0.05 ENSMUST00000091751.3
H2ac22
H2A clustered histone 22
chr7_+_103065903 0.04 ENSMUST00000079348.4
Usp17lc
ubiquitin specific peptidase 17-like C
chr13_+_23398297 0.03 ENSMUST00000236177.2
Vmn1r221
vomeronasal 1 receptor 221
chr12_-_115432252 0.03 ENSMUST00000103533.2
ENSMUST00000197803.2
Ighv8-9
immunoglobulin heavy variable V8-9
chr7_-_31405182 0.03 ENSMUST00000178258.3
Scgb2b7
secretoglobin, family 2B, member 7
chr10_-_120815232 0.02 ENSMUST00000119944.8
ENSMUST00000119093.2
Lemd3
LEM domain containing 3
chr1_-_126420659 0.02 ENSMUST00000161954.8
Nckap5
NCK-associated protein 5
chr13_-_22227114 0.01 ENSMUST00000091741.6
H2ac11
H2A clustered histone 11
chr6_+_51447613 0.00 ENSMUST00000114445.8
ENSMUST00000114446.8
ENSMUST00000141711.3
Cbx3
chromobox 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.3 GO:0072233 ascending thin limb development(GO:0072021) thick ascending limb development(GO:0072023) metanephric ascending thin limb development(GO:0072218) metanephric thick ascending limb development(GO:0072233)
0.4 3.9 GO:0015671 oxygen transport(GO:0015671)
0.4 2.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.3 0.8 GO:0060618 nipple development(GO:0060618)
0.2 2.0 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.2 0.9 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.2 0.6 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.2 0.7 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.2 1.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.2 1.0 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.1 1.6 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.6 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.5 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.1 0.5 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.1 0.6 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.3 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.1 0.4 GO:0046898 response to cycloheximide(GO:0046898)
0.1 0.3 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 1.4 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.1 0.3 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.1 1.8 GO:0043312 neutrophil degranulation(GO:0043312)
0.1 0.3 GO:0030824 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.1 0.4 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023) positive regulation of somatostatin secretion(GO:0090274)
0.1 0.3 GO:1904349 positive regulation of small intestine smooth muscle contraction(GO:1904349)
0.1 0.2 GO:0048817 negative regulation of hair follicle maturation(GO:0048817)
0.1 0.2 GO:0097052 L-kynurenine metabolic process(GO:0097052)
0.1 0.9 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 1.3 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 0.4 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.4 GO:0007527 adult somatic muscle development(GO:0007527)
0.0 0.5 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.0 0.5 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.6 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 3.8 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 1.2 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 0.2 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 2.4 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.7 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.4 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 0.9 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 0.9 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.5 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.9 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0007262 STAT protein import into nucleus(GO:0007262)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 0.6 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 0.6 GO:1990769 proximal neuron projection(GO:1990769)
0.1 1.8 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 1.6 GO:0072687 meiotic spindle(GO:0072687)
0.1 1.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 2.3 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.7 GO:0097449 astrocyte projection(GO:0097449)
0.0 4.6 GO:0000922 spindle pole(GO:0000922)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.5 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0044327 dendritic spine head(GO:0044327)
0.0 1.2 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.4 4.3 GO:0019864 IgG binding(GO:0019864)
0.3 3.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.2 0.5 GO:0016015 morphogen activity(GO:0016015)
0.2 0.6 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.1 0.4 GO:0018169 ribosomal S6-glutamic acid ligase activity(GO:0018169)
0.1 0.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.7 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.3 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 1.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.7 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.2 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 0.9 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.2 GO:0047945 L-phenylalanine:pyruvate aminotransferase activity(GO:0047312) glutamine-phenylpyruvate transaminase activity(GO:0047316) L-glutamine:pyruvate aminotransferase activity(GO:0047945)
0.1 2.3 GO:0070412 R-SMAD binding(GO:0070412)
0.1 6.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 1.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.3 GO:0001179 RNA polymerase I transcription factor binding(GO:0001179)
0.0 1.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.4 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.4 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.0 0.3 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.3 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.6 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.5 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.5 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 1.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.5 GO:0030332 cyclin binding(GO:0030332)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.4 PID AURORA A PATHWAY Aurora A signaling
0.0 1.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.6 PID IL23 PATHWAY IL23-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.4 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases