Project

PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

Navigation
Downloads

Results for Sox1

Z-value: 0.55

Motif logo

logo of

Transcription factors associated with Sox1

Gene Symbol Gene ID Gene Info
Sox1
ENSMUSG00000096014.2 Sox1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Sox1mm39_v1_chr8_+_12445287_12445295-0.788.9e-16Click!

Activity profile of Sox1 motif

Sorted Z-values of Sox1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr17_+_34482183 7.71 ENSMUST00000040828.7
ENSMUST00000237342.2
ENSMUST00000237866.2
H2-Ab1
histocompatibility 2, class II antigen A, beta 1
chr17_-_34506744 7.23 ENSMUST00000174751.2
ENSMUST00000040655.14
H2-Aa
histocompatibility 2, class II antigen A, alpha
chr14_+_65903840 3.42 ENSMUST00000022610.15
Scara5
scavenger receptor class A, member 5
chr1_-_173703424 3.36 ENSMUST00000186442.7
Mndal
myeloid nuclear differentiation antigen like
chr9_-_114219685 3.19 ENSMUST00000084881.5
Crtap
cartilage associated protein
chr17_+_48047955 2.73 ENSMUST00000086932.10
Tfeb
transcription factor EB
chr2_+_84629172 2.70 ENSMUST00000102642.9
ENSMUST00000150325.2
Ube2l6
ubiquitin-conjugating enzyme E2L 6
chr6_+_37507108 2.56 ENSMUST00000040987.11
Akr1d1
aldo-keto reductase family 1, member D1
chr15_-_74869483 2.51 ENSMUST00000023248.13
Ly6a
lymphocyte antigen 6 complex, locus A
chr15_-_74869684 2.14 ENSMUST00000190188.2
ENSMUST00000189068.7
ENSMUST00000186526.7
ENSMUST00000187171.2
ENSMUST00000187994.7
Ly6a
lymphocyte antigen 6 complex, locus A
chr14_+_65903878 2.13 ENSMUST00000069226.7
Scara5
scavenger receptor class A, member 5
chr5_+_21391282 2.11 ENSMUST00000036031.13
ENSMUST00000198937.2
Gsap
gamma-secretase activating protein
chr6_-_52195663 2.09 ENSMUST00000134367.4
Hoxa7
homeobox A7
chr1_+_171723231 1.90 ENSMUST00000097466.3
Gm10521
predicted gene 10521
chr4_-_131664478 1.85 ENSMUST00000155990.8
Epb41
erythrocyte membrane protein band 4.1
chr7_+_67305162 1.79 ENSMUST00000107470.2
Ttc23
tetratricopeptide repeat domain 23
chr2_-_84481101 1.74 ENSMUST00000111691.2
Ctnnd1
catenin (cadherin associated protein), delta 1
chr14_-_56339915 1.58 ENSMUST00000015583.2
Ctsg
cathepsin G
chr2_-_84481058 1.54 ENSMUST00000111670.9
ENSMUST00000111697.9
ENSMUST00000111696.8
ENSMUST00000111678.8
ENSMUST00000111690.8
ENSMUST00000111695.8
ENSMUST00000111677.8
ENSMUST00000111698.8
ENSMUST00000099941.9
ENSMUST00000111676.8
ENSMUST00000111694.8
ENSMUST00000111675.8
ENSMUST00000111689.8
ENSMUST00000111687.8
ENSMUST00000111692.8
ENSMUST00000111685.8
ENSMUST00000111686.8
ENSMUST00000111688.8
ENSMUST00000111693.8
ENSMUST00000111684.8
Ctnnd1
catenin (cadherin associated protein), delta 1
chr19_+_18818001 1.53 ENSMUST00000237020.2
Trpm6
transient receptor potential cation channel, subfamily M, member 6
chr11_-_69768875 1.49 ENSMUST00000178597.3
Tmem95
transmembrane protein 95
chr1_-_194813843 1.42 ENSMUST00000075451.12
ENSMUST00000191775.2
Cr1l
complement component (3b/4b) receptor 1-like
chr19_-_8382424 1.40 ENSMUST00000064507.12
ENSMUST00000120540.2
ENSMUST00000096269.11
Slc22a30
solute carrier family 22, member 30
chr11_+_96024612 1.36 ENSMUST00000167258.8
Ttll6
tubulin tyrosine ligase-like family, member 6
chrX_+_100473161 1.30 ENSMUST00000033673.7
Nono
non-POU-domain-containing, octamer binding protein
chr13_+_42454922 1.14 ENSMUST00000021796.9
Edn1
endothelin 1
chr12_+_52144511 1.13 ENSMUST00000040090.16
Nubpl
nucleotide binding protein-like
chr7_+_119289249 1.05 ENSMUST00000047045.10
Acsm4
acyl-CoA synthetase medium-chain family member 4
chr1_-_194813631 0.94 ENSMUST00000194111.6
ENSMUST00000193094.6
Cr1l
complement component (3b/4b) receptor 1-like
chr9_+_44238089 0.88 ENSMUST00000054708.5
Dpagt1
dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr3_+_90497554 0.82 ENSMUST00000179550.2
S100a2
S100 calcium binding protein A2
chr3_+_60503051 0.81 ENSMUST00000192757.6
ENSMUST00000193518.6
ENSMUST00000195817.3
Mbnl1
muscleblind like splicing factor 1
chr6_+_70170212 0.74 ENSMUST00000103382.2
Igkv8-26
immunoglobulin kappa variable 8-26
chr6_+_70332836 0.74 ENSMUST00000103390.3
Igkv8-18
immunoglobulin kappa variable 8-18
chr9_+_123596276 0.72 ENSMUST00000166236.9
ENSMUST00000111454.4
ENSMUST00000168910.2
Ccr9
chemokine (C-C motif) receptor 9
chr8_-_89362745 0.71 ENSMUST00000034087.9
Snx20
sorting nexin 20
chr2_+_87185159 0.65 ENSMUST00000215163.3
Olfr1120
olfactory receptor 1120
chr15_-_74920518 0.62 ENSMUST00000185372.2
ENSMUST00000187347.7
ENSMUST00000188845.7
ENSMUST00000185200.7
ENSMUST00000179762.8
ENSMUST00000191216.7
ENSMUST00000065408.16
Ly6c1
lymphocyte antigen 6 complex, locus C1
chr11_+_73244561 0.57 ENSMUST00000108465.4
Olfr20
olfactory receptor 20
chrX_+_162945162 0.55 ENSMUST00000131543.2
Ace2
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr7_+_13357892 0.54 ENSMUST00000108525.4
Sult2a5
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 5
chr4_-_120604445 0.53 ENSMUST00000030376.8
Kcnq4
potassium voltage-gated channel, subfamily Q, member 4
chr5_+_21942139 0.51 ENSMUST00000030882.12
Pmpcb
peptidase (mitochondrial processing) beta
chr11_+_96025045 0.48 ENSMUST00000107680.2
Ttll6
tubulin tyrosine ligase-like family, member 6
chr14_+_54032814 0.47 ENSMUST00000103671.4
Trav13-5
T cell receptor alpha variable 13-5
chr7_+_103620359 0.45 ENSMUST00000209473.4
Olfr635
olfactory receptor 635
chr7_+_79992839 0.44 ENSMUST00000032747.7
ENSMUST00000206480.2
ENSMUST00000206074.2
ENSMUST00000206122.2
Hddc3
HD domain containing 3
chr9_+_123921573 0.43 ENSMUST00000111442.3
ENSMUST00000171499.3
Ccr5
chemokine (C-C motif) receptor 5
chr2_-_34645241 0.42 ENSMUST00000102800.9
Gapvd1
GTPase activating protein and VPS9 domains 1
chr3_+_32490300 0.40 ENSMUST00000029201.14
Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
chr9_-_108183140 0.40 ENSMUST00000195615.2
Tcta
T cell leukemia translocation altered gene
chr16_-_37474772 0.39 ENSMUST00000023514.4
Ndufb4
NADH:ubiquinone oxidoreductase subunit B4
chr4_+_63478478 0.37 ENSMUST00000080336.4
Tmem268
transmembrane protein 268
chr2_+_87726521 0.37 ENSMUST00000052300.2
Olfr1153
olfactory receptor 1153
chr5_-_82272549 0.36 ENSMUST00000188072.2
ENSMUST00000185410.2
1700031L13Rik
RIKEN cDNA 1700031L13 gene
chr17_+_35188888 0.34 ENSMUST00000173680.2
Gm20481
predicted gene 20481
chr17_-_21134625 0.21 ENSMUST00000077001.3
Vmn1r232
vomeronasal 1 receptor 232
chr14_-_35533922 0.20 ENSMUST00000043266.7
4930596D02Rik
RIKEN cDNA 4930596D02 gene
chr2_+_34296783 0.19 ENSMUST00000149383.8
ENSMUST00000124443.8
ENSMUST00000141253.2
ENSMUST00000113124.8
Mapkap1
mitogen-activated protein kinase associated protein 1
chr7_-_119744509 0.17 ENSMUST00000208874.2
ENSMUST00000033207.6
Zp2
zona pellucida glycoprotein 2
chr6_-_66757618 0.17 ENSMUST00000227493.2
Vmn1r38
vomeronasal 1 receptor 38
chr8_+_13209141 0.16 ENSMUST00000033824.8
Lamp1
lysosomal-associated membrane protein 1
chr6_+_121160626 0.13 ENSMUST00000118234.8
ENSMUST00000088561.10
ENSMUST00000137432.8
ENSMUST00000120066.8
Pex26
peroxisomal biogenesis factor 26
chr2_+_88644840 0.11 ENSMUST00000214703.2
Olfr1202
olfactory receptor 1202
chr11_+_49355873 0.11 ENSMUST00000213674.2
ENSMUST00000204518.3
Olfr1386
olfactory receptor 1386
chr18_-_70409277 0.08 ENSMUST00000239144.2
Gm36255
predicted gene, 36255
chr7_-_103710652 0.05 ENSMUST00000074064.5
4930516K23Rik
RIKEN cDNA 4930516K23 gene
chr6_+_114625771 0.04 ENSMUST00000182510.8
Atg7
autophagy related 7

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.7 GO:0002343 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
1.1 3.2 GO:1901873 regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
0.9 2.6 GO:0030573 bile acid catabolic process(GO:0030573)
0.7 2.7 GO:0009816 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.5 3.3 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.4 1.1 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.4 7.2 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.3 2.7 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.3 1.8 GO:0051013 microtubule severing(GO:0051013)
0.2 0.7 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.2 2.4 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.2 5.5 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.2 2.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.2 1.6 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.1 1.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 2.1 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 0.5 GO:0015827 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.1 0.4 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.9 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 1.8 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 1.3 GO:0015747 urate transport(GO:0015747)
0.1 0.4 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 0.5 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.1 0.2 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.5 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 1.5 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.4 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:0060468 prevention of polyspermy(GO:0060468)
0.0 0.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 3.4 GO:0030308 negative regulation of cell growth(GO:0030308)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 14.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 3.3 GO:0005915 zonula adherens(GO:0005915)
0.2 1.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 1.3 GO:0042382 paraspeckles(GO:0042382)
0.1 0.2 GO:0061474 phagolysosome membrane(GO:0061474)
0.0 0.5 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 2.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.8 GO:0099738 cell cortex region(GO:0099738)
0.0 5.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.5 GO:0031526 brush border membrane(GO:0031526)
0.0 0.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.2 GO:0031932 TORC2 complex(GO:0031932)
0.0 1.8 GO:0036064 ciliary basal body(GO:0036064)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.5 GO:0070287 ferritin receptor activity(GO:0070287)
0.5 2.6 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.5 7.4 GO:1990405 protein antigen binding(GO:1990405)
0.5 2.7 GO:0042296 ISG15 transferase activity(GO:0042296)
0.3 1.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.2 0.9 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.2 7.2 GO:0042605 peptide antigen binding(GO:0042605)
0.2 1.8 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.1 1.0 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.1 0.5 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 1.3 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.8 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 1.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.2 GO:0032190 acrosin binding(GO:0032190)
0.1 1.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 2.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.1 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 4.7 GO:0001047 core promoter binding(GO:0001047)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 1.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.8 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.1 PID ENDOTHELIN PATHWAY Endothelins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 0.4 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 1.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 2.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 3.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.9 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.6 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions