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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Sox30

Z-value: 0.74

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Transcription factors associated with Sox30

Gene Symbol Gene ID Gene Info
Sox30
ENSMUSG00000040489.6 Sox30

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Sox30mm39_v1_chr11_+_45871135_458711640.142.5e-01Click!

Activity profile of Sox30 motif

Sorted Z-values of Sox30 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox30

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_-_3494587 6.09 ENSMUST00000049985.15
Hepacam2
HEPACAM family member 2
chr7_+_43874752 5.29 ENSMUST00000075162.5
Klk1
kallikrein 1
chr6_-_136758716 5.25 ENSMUST00000078095.11
ENSMUST00000032338.10
Gucy2c
guanylate cyclase 2c
chr6_+_41512480 4.99 ENSMUST00000103289.2
ENSMUST00000103290.2
ENSMUST00000193061.2
Trbj1-6
Trbj1-7
T cell receptor beta joining 1-6
T cell receptor beta joining 1-7
chr10_+_28544356 4.65 ENSMUST00000060409.13
ENSMUST00000056097.11
ENSMUST00000105516.9
Themis
thymocyte selection associated
chr6_+_41511733 4.21 ENSMUST00000103287.2
Trbj1-4
T cell receptor beta joining 1-4
chr6_-_24168082 4.15 ENSMUST00000031713.9
Slc13a1
solute carrier family 13 (sodium/sulfate symporters), member 1
chr17_-_31363245 3.95 ENSMUST00000024826.8
Tff2
trefoil factor 2 (spasmolytic protein 1)
chr10_+_17672004 3.66 ENSMUST00000037964.7
Txlnb
taxilin beta
chr6_+_41512010 3.58 ENSMUST00000103288.2
Trbj1-5
T cell receptor beta joining 1-5
chr10_+_96453408 3.50 ENSMUST00000218953.2
Btg1
BTG anti-proliferation factor 1
chr2_-_84652890 3.45 ENSMUST00000028471.6
Smtnl1
smoothelin-like 1
chr9_-_32452885 3.10 ENSMUST00000016231.14
Fli1
Friend leukemia integration 1
chr3_-_113198765 3.06 ENSMUST00000179568.3
Amy2a4
amylase 2a4
chr14_-_68893253 3.03 ENSMUST00000225767.3
ENSMUST00000111072.8
ENSMUST00000022642.6
ENSMUST00000224039.2
Adam28
a disintegrin and metallopeptidase domain 28
chr1_-_37535170 2.91 ENSMUST00000148047.2
Mgat4a
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr1_+_135656885 2.90 ENSMUST00000027677.8
Csrp1
cysteine and glycine-rich protein 1
chr10_+_28544556 2.85 ENSMUST00000161345.2
Themis
thymocyte selection associated
chr11_-_116572116 2.78 ENSMUST00000144398.2
St6galnac2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr12_+_31488208 2.72 ENSMUST00000001254.6
Slc26a3
solute carrier family 26, member 3
chr17_-_79662514 2.66 ENSMUST00000068958.9
Cdc42ep3
CDC42 effector protein (Rho GTPase binding) 3
chr16_+_3854806 2.51 ENSMUST00000137748.8
ENSMUST00000006136.11
ENSMUST00000157044.8
ENSMUST00000120009.8
Dnase1
deoxyribonuclease I
chr11_+_3933699 2.44 ENSMUST00000063004.14
Gal3st1
galactose-3-O-sulfotransferase 1
chr11_+_3933636 2.29 ENSMUST00000078757.8
Gal3st1
galactose-3-O-sulfotransferase 1
chr11_+_94858417 2.26 ENSMUST00000038928.7
H1f9
H1.9 linker histone
chr2_+_127750978 2.17 ENSMUST00000110344.2
Acoxl
acyl-Coenzyme A oxidase-like
chr3_-_9029097 2.15 ENSMUST00000091354.12
ENSMUST00000094381.11
Tpd52
tumor protein D52
chr3_-_9898713 2.08 ENSMUST00000161949.8
Pag1
phosphoprotein associated with glycosphingolipid microdomains 1
chr5_+_92957231 2.06 ENSMUST00000113054.9
Shroom3
shroom family member 3
chr6_-_136899167 1.89 ENSMUST00000032343.7
Erp27
endoplasmic reticulum protein 27
chr19_+_34194990 1.86 ENSMUST00000119603.2
Stambpl1
STAM binding protein like 1
chr6_-_87312743 1.83 ENSMUST00000042025.12
ENSMUST00000205033.2
Antxr1
anthrax toxin receptor 1
chr11_+_21041291 1.79 ENSMUST00000093290.12
Peli1
pellino 1
chr4_-_73869071 1.76 ENSMUST00000095023.2
ENSMUST00000030101.4
2310002L09Rik
RIKEN cDNA 2310002L09 gene
chr9_-_72019109 1.73 ENSMUST00000183404.8
ENSMUST00000184783.8
Tcf12
transcription factor 12
chrX_-_133062677 1.67 ENSMUST00000033611.5
Xkrx
X-linked Kx blood group related, X-linked
chr1_+_78488499 1.67 ENSMUST00000012331.7
Mogat1
monoacylglycerol O-acyltransferase 1
chr5_+_102992873 1.65 ENSMUST00000070000.6
Arhgap24
Rho GTPase activating protein 24
chr1_+_78488440 1.62 ENSMUST00000152111.2
Mogat1
monoacylglycerol O-acyltransferase 1
chr11_-_106606076 1.62 ENSMUST00000080853.11
ENSMUST00000183610.8
ENSMUST00000103069.10
ENSMUST00000106796.9
Pecam1
platelet/endothelial cell adhesion molecule 1
chr11_-_106605772 1.59 ENSMUST00000124958.3
Pecam1
platelet/endothelial cell adhesion molecule 1
chr11_+_67128843 1.55 ENSMUST00000018632.11
Myh4
myosin, heavy polypeptide 4, skeletal muscle
chr12_-_99849660 1.46 ENSMUST00000221929.2
ENSMUST00000046485.5
Efcab11
EF-hand calcium binding domain 11
chr3_-_9898676 1.39 ENSMUST00000108384.9
Pag1
phosphoprotein associated with glycosphingolipid microdomains 1
chr8_-_23143422 1.38 ENSMUST00000033938.7
Polb
polymerase (DNA directed), beta
chr10_-_37014859 1.37 ENSMUST00000092584.6
Marcks
myristoylated alanine rich protein kinase C substrate
chr10_-_62628008 1.31 ENSMUST00000217768.2
ENSMUST00000020268.7
ENSMUST00000218946.2
ENSMUST00000219527.2
Ccar1
cell division cycle and apoptosis regulator 1
chr3_-_105940130 1.29 ENSMUST00000200146.2
Chil5
chitinase-like 5
chr9_-_72019053 1.28 ENSMUST00000183492.8
ENSMUST00000184523.8
ENSMUST00000034755.13
Tcf12
transcription factor 12
chr4_-_116263183 1.27 ENSMUST00000123072.8
ENSMUST00000144281.2
Mast2
microtubule associated serine/threonine kinase 2
chr18_-_88945571 1.26 ENSMUST00000147313.2
Socs6
suppressor of cytokine signaling 6
chr9_+_7764042 1.24 ENSMUST00000052865.16
Tmem123
transmembrane protein 123
chr9_-_72018453 1.17 ENSMUST00000183992.8
Tcf12
transcription factor 12
chr9_+_111014254 1.17 ENSMUST00000198986.2
Lrrfip2
leucine rich repeat (in FLII) interacting protein 2
chr9_-_72018933 1.14 ENSMUST00000185117.8
Tcf12
transcription factor 12
chr11_+_43365103 1.12 ENSMUST00000173002.8
ENSMUST00000057679.10
C1qtnf2
C1q and tumor necrosis factor related protein 2
chr5_+_146769700 1.09 ENSMUST00000035983.12
Rpl21
ribosomal protein L21
chr2_-_62242562 1.03 ENSMUST00000047812.8
Dpp4
dipeptidylpeptidase 4
chr2_-_181240921 1.00 ENSMUST00000060173.9
Samd10
sterile alpha motif domain containing 10
chr19_-_56810593 0.99 ENSMUST00000118592.8
Ccdc186
coiled-coil domain containing 186
chr7_-_109330915 0.99 ENSMUST00000035372.3
Ascl3
achaete-scute family bHLH transcription factor 3
chr6_-_129449739 0.91 ENSMUST00000112076.9
ENSMUST00000184581.3
Clec7a
C-type lectin domain family 7, member a
chr5_+_36050663 0.84 ENSMUST00000064571.11
Afap1
actin filament associated protein 1
chr4_+_109200225 0.81 ENSMUST00000030281.12
Eps15
epidermal growth factor receptor pathway substrate 15
chr9_+_39985125 0.73 ENSMUST00000054051.5
Olfr982
olfactory receptor 982
chr2_+_152873772 0.73 ENSMUST00000037235.7
Xkr7
X-linked Kx blood group related 7
chr7_-_85956319 0.71 ENSMUST00000055690.3
Olfr309
olfactory receptor 309
chr9_+_55448432 0.69 ENSMUST00000034869.11
Isl2
insulin related protein 2 (islet 2)
chr4_+_83335947 0.64 ENSMUST00000030206.10
ENSMUST00000071544.11
Snapc3
small nuclear RNA activating complex, polypeptide 3
chr5_-_137101108 0.62 ENSMUST00000077523.4
ENSMUST00000041388.11
Serpine1
serine (or cysteine) peptidase inhibitor, clade E, member 1
chr8_-_86281946 0.61 ENSMUST00000034138.7
Dnaja2
DnaJ heat shock protein family (Hsp40) member A2
chr10_+_33071964 0.55 ENSMUST00000219211.2
Trdn
triadin
chr13_-_43632368 0.54 ENSMUST00000222651.2
Ranbp9
RAN binding protein 9
chr14_-_19873839 0.53 ENSMUST00000022341.7
Rtraf
RNA transcription, translation and transport factor
chr19_+_44282113 0.52 ENSMUST00000026221.7
Scd2
stearoyl-Coenzyme A desaturase 2
chr3_+_90383425 0.51 ENSMUST00000001042.10
Ilf2
interleukin enhancer binding factor 2
chr9_-_103357564 0.51 ENSMUST00000124310.5
Bfsp2
beaded filament structural protein 2, phakinin
chr1_-_176641607 0.51 ENSMUST00000195717.6
ENSMUST00000192961.6
Cep170
centrosomal protein 170
chr13_-_56283331 0.49 ENSMUST00000045788.9
ENSMUST00000016081.13
Macroh2a1
macroH2A.1 histone
chr3_-_106729898 0.48 ENSMUST00000059486.3
Olfr266
olfactory receptor 266
chr7_+_43661592 0.46 ENSMUST00000048945.6
Klk1b26
kallikrein 1-related petidase b26
chr9_-_60418286 0.45 ENSMUST00000098660.10
Thsd4
thrombospondin, type I, domain containing 4
chr19_-_24454720 0.37 ENSMUST00000099556.2
Fam122a
family with sequence similarity 122, member A
chr11_-_58521327 0.37 ENSMUST00000214132.2
Olfr323
olfactory receptor 323
chr2_-_35257741 0.36 ENSMUST00000028243.2
4930568D16Rik
RIKEN cDNA 4930568D16 gene
chr9_+_7571397 0.34 ENSMUST00000120900.8
ENSMUST00000151853.8
ENSMUST00000152878.3
Mmp27
matrix metallopeptidase 27
chr17_-_34337446 0.32 ENSMUST00000095347.13
Brd2
bromodomain containing 2
chr7_-_104986921 0.31 ENSMUST00000057528.2
Olfr691
olfactory receptor 691
chr13_-_103094784 0.27 ENSMUST00000172264.8
ENSMUST00000099202.10
Mast4
microtubule associated serine/threonine kinase family member 4
chr1_-_151376544 0.23 ENSMUST00000187991.2
ENSMUST00000187048.7
ENSMUST00000186415.7
Rnf2
ring finger protein 2
chr2_-_119617985 0.22 ENSMUST00000110793.8
ENSMUST00000099529.9
ENSMUST00000048493.12
Rpap1
RNA polymerase II associated protein 1
chr4_-_119047202 0.19 ENSMUST00000239029.2
ENSMUST00000138395.9
ENSMUST00000156746.3
Ermap
erythroblast membrane-associated protein
chr2_+_111311164 0.18 ENSMUST00000120021.5
Olfr1289
olfactory receptor 1289
chr2_+_85545763 0.16 ENSMUST00000216443.3
Olfr1009
olfactory receptor 1009
chr7_+_108143734 0.15 ENSMUST00000078162.4
ENSMUST00000211693.2
Olfr503
olfactory receptor 503
chr6_-_132604474 0.15 ENSMUST00000091791.6
A630073D07Rik
RIKEN cDNA A630073D07 gene
chr4_-_119047167 0.15 ENSMUST00000030396.15
Ermap
erythroblast membrane-associated protein
chr4_+_109092610 0.14 ENSMUST00000106628.8
Calr4
calreticulin 4
chr4_+_109092829 0.14 ENSMUST00000030285.8
Calr4
calreticulin 4
chr2_-_89583170 0.13 ENSMUST00000099765.2
Olfr1253
olfactory receptor 1253
chr8_+_109429732 0.12 ENSMUST00000188994.2
Zfhx3
zinc finger homeobox 3
chr5_-_87739442 0.11 ENSMUST00000031201.9
Sult1e1
sulfotransferase family 1E, member 1
chr4_+_136011969 0.09 ENSMUST00000144217.8
Zfp46
zinc finger protein 46
chr4_-_119047180 0.09 ENSMUST00000150864.3
ENSMUST00000141227.9
Ermap
erythroblast membrane-associated protein
chr1_+_38037086 0.08 ENSMUST00000027252.8
Eif5b
eukaryotic translation initiation factor 5B
chr4_-_119047146 0.05 ENSMUST00000124626.9
Ermap
erythroblast membrane-associated protein
chr4_+_134123631 0.05 ENSMUST00000105869.9
Pafah2
platelet-activating factor acetylhydrolase 2
chr6_-_122317156 0.04 ENSMUST00000159384.8
Phc1
polyhomeotic 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0090673 endothelial cell-matrix adhesion(GO:0090673)
0.6 3.9 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.5 3.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.5 4.7 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.5 2.9 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.5 1.4 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.4 2.8 GO:0097503 sialylation(GO:0097503)
0.4 3.5 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.3 7.5 GO:0043383 negative T cell selection(GO:0043383)
0.3 6.9 GO:0008272 sulfate transport(GO:0008272)
0.2 1.2 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway(GO:0035660)
0.2 0.7 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.2 0.6 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 2.7 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.2 1.7 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.2 1.8 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 1.3 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 5.0 GO:0014823 response to activity(GO:0014823)
0.1 5.3 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.1 0.5 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 2.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.5 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 1.3 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 3.1 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.8 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1 2.5 GO:0006308 DNA catabolic process(GO:0006308)
0.1 0.6 GO:0009301 snRNA transcription(GO:0009301)
0.0 1.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 1.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.5 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.0 0.1 GO:0006711 estrogen catabolic process(GO:0006711)
0.0 1.1 GO:0070208 positive regulation of fatty acid oxidation(GO:0046321) protein heterotrimerization(GO:0070208)
0.0 5.9 GO:0007098 centrosome cycle(GO:0007098)
0.0 4.7 GO:0050868 negative regulation of T cell activation(GO:0050868)
0.0 2.9 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.5 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 2.9 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.4 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.6 GO:0042026 protein refolding(GO:0042026)
0.0 1.5 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 1.4 GO:0042585 germinal vesicle(GO:0042585)
0.2 5.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.5 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 1.0 GO:0071438 invadopodium membrane(GO:0071438)
0.1 7.5 GO:0008180 COP9 signalosome(GO:0008180)
0.1 1.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.6 GO:0042583 chromaffin granule(GO:0042583)
0.1 1.6 GO:0032982 myosin filament(GO:0032982)
0.1 2.7 GO:0097225 sperm midpiece(GO:0097225)
0.1 1.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 3.5 GO:0031430 M band(GO:0031430)
0.0 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.8 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 6.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 5.6 GO:0030496 midbody(GO:0030496)
0.0 0.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.4 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 1.3 GO:0001772 immunological synapse(GO:0001772)
0.0 7.5 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.7 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.5 3.3 GO:0004144 2-acylglycerol O-acyltransferase activity(GO:0003846) diacylglycerol O-acyltransferase activity(GO:0004144)
0.4 3.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.4 6.9 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.3 3.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.3 5.3 GO:0035497 cAMP response element binding(GO:0035497)
0.3 2.9 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3 5.3 GO:0015643 toxic substance binding(GO:0015643)
0.2 2.5 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.2 3.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 2.2 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 1.3 GO:0004568 chitinase activity(GO:0004568)
0.1 3.5 GO:0005523 tropomyosin binding(GO:0005523)
0.1 2.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.5 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 2.8 GO:0008373 sialyltransferase activity(GO:0008373)
0.1 1.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.4 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0 5.3 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 1.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 3.7 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 3.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.1 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 1.9 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 1.8 GO:0005518 collagen binding(GO:0005518)
0.0 2.1 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 1.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.8 GO:0042169 SH2 domain binding(GO:0042169)
0.0 1.4 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 1.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 3.6 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 1.3 GO:0004860 protein kinase inhibitor activity(GO:0004860)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 3.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 3.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 3.5 PID SHP2 PATHWAY SHP2 signaling
0.0 0.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 3.5 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 3.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 1.8 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 2.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 2.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 4.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 5.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.8 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 2.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 2.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.6 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription