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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Sox4

Z-value: 0.78

Motif logo

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Transcription factors associated with Sox4

Gene Symbol Gene ID Gene Info
Sox4
ENSMUSG00000076431.5 Sox4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Sox4mm39_v1_chr13_-_29137673_291376960.523.4e-06Click!

Activity profile of Sox4 motif

Sorted Z-values of Sox4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox4

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr9_+_119978773 10.08 ENSMUST00000068698.15
ENSMUST00000215512.2
ENSMUST00000111627.3
ENSMUST00000093773.8
Mobp
myelin-associated oligodendrocytic basic protein
chr12_-_72283465 7.24 ENSMUST00000021497.16
ENSMUST00000137990.2
Rtn1
reticulon 1
chr19_-_46315543 7.13 ENSMUST00000223917.2
ENSMUST00000224447.2
ENSMUST00000041391.5
ENSMUST00000096029.12
Psd
pleckstrin and Sec7 domain containing
chr7_-_30614249 6.49 ENSMUST00000190950.7
ENSMUST00000187137.7
ENSMUST00000190638.7
Mag
myelin-associated glycoprotein
chr12_-_111638722 6.27 ENSMUST00000001304.9
Ckb
creatine kinase, brain
chr1_-_93029547 6.19 ENSMUST00000112958.9
ENSMUST00000186861.2
ENSMUST00000171556.8
Kif1a
kinesin family member 1A
chr1_-_93029532 6.08 ENSMUST00000171796.8
Kif1a
kinesin family member 1A
chr12_-_72455708 5.99 ENSMUST00000078505.14
Rtn1
reticulon 1
chr18_+_82572595 5.94 ENSMUST00000152071.9
ENSMUST00000142850.9
ENSMUST00000080658.12
ENSMUST00000133193.9
ENSMUST00000123251.9
ENSMUST00000153478.9
ENSMUST00000075372.13
ENSMUST00000102812.12
ENSMUST00000062446.15
ENSMUST00000114674.11
ENSMUST00000132369.3
Mbp
myelin basic protein
chr3_-_50398027 5.18 ENSMUST00000029297.6
ENSMUST00000194462.6
Slc7a11
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr10_-_116309764 5.07 ENSMUST00000068233.11
Kcnmb4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr8_-_4309257 5.03 ENSMUST00000053252.9
Ctxn1
cortexin 1
chr1_-_93029576 4.82 ENSMUST00000190723.7
Kif1a
kinesin family member 1A
chr5_-_146521629 4.40 ENSMUST00000200112.2
ENSMUST00000197431.2
ENSMUST00000197825.2
Gpr12
G-protein coupled receptor 12
chr7_+_87233554 4.38 ENSMUST00000125009.9
Grm5
glutamate receptor, metabotropic 5
chr3_+_8574420 4.15 ENSMUST00000029002.9
Stmn2
stathmin-like 2
chr18_-_43192483 4.12 ENSMUST00000025377.14
Ppp2r2b
protein phosphatase 2, regulatory subunit B, beta
chr12_+_24881582 4.08 ENSMUST00000221952.2
ENSMUST00000078902.8
ENSMUST00000110942.11
Mboat2
membrane bound O-acyltransferase domain containing 2
chr12_-_81827893 4.04 ENSMUST00000035987.9
Map3k9
mitogen-activated protein kinase kinase kinase 9
chr9_+_59614877 4.03 ENSMUST00000128944.8
ENSMUST00000098661.10
Gramd2
GRAM domain containing 2
chr1_+_158189831 3.70 ENSMUST00000193042.6
ENSMUST00000046110.16
Astn1
astrotactin 1
chr11_+_54205722 3.66 ENSMUST00000072178.11
ENSMUST00000101211.9
ENSMUST00000101213.9
ENSMUST00000064690.10
ENSMUST00000108899.8
Acsl6
acyl-CoA synthetase long-chain family member 6
chr14_+_55173696 3.63 ENSMUST00000037814.8
Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
chr9_-_103357564 3.62 ENSMUST00000124310.5
Bfsp2
beaded filament structural protein 2, phakinin
chr1_-_79838897 3.31 ENSMUST00000190724.2
Serpine2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr4_+_129407374 3.31 ENSMUST00000062356.7
Marcksl1
MARCKS-like 1
chr4_-_149211145 3.25 ENSMUST00000030815.3
Cort
cortistatin
chr17_+_12338161 3.20 ENSMUST00000024594.9
Agpat4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr15_+_30457772 2.83 ENSMUST00000228282.2
Ctnnd2
catenin (cadherin associated protein), delta 2
chr14_+_14159978 2.81 ENSMUST00000137133.2
ENSMUST00000036070.15
ENSMUST00000121887.8
Fam107a
family with sequence similarity 107, member A
chr1_+_153541020 2.78 ENSMUST00000152114.8
ENSMUST00000111812.8
Rgs8
regulator of G-protein signaling 8
chr13_+_117356808 2.66 ENSMUST00000022242.9
Emb
embigin
chr18_+_37617848 2.63 ENSMUST00000053856.6
Pcdhb17
protocadherin beta 17
chr14_+_55173936 2.59 ENSMUST00000227441.2
Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
chr16_+_16964801 2.57 ENSMUST00000232479.2
ENSMUST00000232344.2
ENSMUST00000069064.7
Ydjc
YdjC homolog (bacterial)
chrX_+_158623460 2.54 ENSMUST00000112451.8
ENSMUST00000112453.9
Sh3kbp1
SH3-domain kinase binding protein 1
chr3_-_143910926 2.41 ENSMUST00000120539.8
ENSMUST00000196264.5
Lmo4
LIM domain only 4
chr6_+_71684846 2.37 ENSMUST00000212792.2
Reep1
receptor accessory protein 1
chr1_-_131127825 2.35 ENSMUST00000068564.15
Rassf5
Ras association (RalGDS/AF-6) domain family member 5
chr12_+_29578354 2.25 ENSMUST00000218583.2
ENSMUST00000049784.17
Myt1l
myelin transcription factor 1-like
chr6_+_71684872 2.17 ENSMUST00000212631.2
Reep1
receptor accessory protein 1
chr12_+_24880878 2.15 ENSMUST00000222198.2
Mboat2
membrane bound O-acyltransferase domain containing 2
chr2_-_165740864 2.07 ENSMUST00000136842.2
Zmynd8
zinc finger, MYND-type containing 8
chr10_+_29019645 2.06 ENSMUST00000092629.4
Soga3
SOGA family member 3
chr17_+_69144053 2.05 ENSMUST00000178545.3
Tmem200c
transmembrane protein 200C
chr14_-_61283911 2.05 ENSMUST00000111234.10
ENSMUST00000224371.2
Tnfrsf19
tumor necrosis factor receptor superfamily, member 19
chr11_+_45946800 1.83 ENSMUST00000011400.8
Adam19
a disintegrin and metallopeptidase domain 19 (meltrin beta)
chr4_-_91288221 1.82 ENSMUST00000102799.10
Elavl2
ELAV like RNA binding protein 1
chr19_-_18978463 1.76 ENSMUST00000040153.15
ENSMUST00000112828.8
Rorb
RAR-related orphan receptor beta
chr18_+_37630044 1.67 ENSMUST00000059571.7
Pcdhb19
protocadherin beta 19
chr6_+_137229427 1.65 ENSMUST00000077115.13
Ptpro
protein tyrosine phosphatase, receptor type, O
chr3_-_143908111 1.64 ENSMUST00000121796.8
Lmo4
LIM domain only 4
chr3_-_143908060 1.57 ENSMUST00000121112.6
Lmo4
LIM domain only 4
chr5_+_20112704 1.55 ENSMUST00000115267.7
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr1_-_131441962 1.52 ENSMUST00000185445.3
Srgap2
SLIT-ROBO Rho GTPase activating protein 2
chr11_-_106050927 1.52 ENSMUST00000045923.10
Limd2
LIM domain containing 2
chr11_-_113956996 1.49 ENSMUST00000041627.14
Sdk2
sidekick cell adhesion molecule 2
chr6_-_23839136 1.37 ENSMUST00000166458.9
ENSMUST00000142913.9
ENSMUST00000069074.14
ENSMUST00000115361.9
ENSMUST00000018122.14
ENSMUST00000115356.3
Cadps2
Ca2+-dependent activator protein for secretion 2
chr1_+_158189900 1.35 ENSMUST00000170718.7
Astn1
astrotactin 1
chr5_+_122534900 1.29 ENSMUST00000196969.5
Arpc3
actin related protein 2/3 complex, subunit 3
chr18_+_65022035 1.27 ENSMUST00000224385.3
ENSMUST00000163516.9
Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr3_-_127631068 1.23 ENSMUST00000051737.8
ENSMUST00000200409.5
Ap1ar
adaptor-related protein complex 1 associated regulatory protein
chr11_-_78388560 1.21 ENSMUST00000061174.7
Sarm1
sterile alpha and HEAT/Armadillo motif containing 1
chr17_-_36015484 1.20 ENSMUST00000117301.8
Ddr1
discoidin domain receptor family, member 1
chr19_+_44919585 1.18 ENSMUST00000096053.5
Slf2
SMC5-SMC6 complex localization factor 2
chr16_-_18885809 1.17 ENSMUST00000200211.2
Iglj3
immunoglobulin lambda joining 3
chr3_-_105940130 1.11 ENSMUST00000200146.2
Chil5
chitinase-like 5
chr18_+_37622518 1.11 ENSMUST00000055949.4
Pcdhb18
protocadherin beta 18
chr18_+_37433852 1.10 ENSMUST00000051754.2
Pcdhb3
protocadherin beta 3
chr2_-_26854283 1.10 ENSMUST00000136710.2
ENSMUST00000064244.11
ENSMUST00000114020.10
Rexo4
REX4, 3'-5' exonuclease
chr7_-_100164007 1.10 ENSMUST00000207405.2
Dnajb13
DnaJ heat shock protein family (Hsp40) member B13
chr1_-_36982747 1.07 ENSMUST00000185964.3
Tmem131
transmembrane protein 131
chr8_+_89423645 1.04 ENSMUST00000043526.15
ENSMUST00000211554.2
ENSMUST00000209532.2
ENSMUST00000209559.2
Cyld
CYLD lysine 63 deubiquitinase
chr11_-_78388284 1.04 ENSMUST00000108287.10
Sarm1
sterile alpha and HEAT/Armadillo motif containing 1
chr5_+_20112500 1.00 ENSMUST00000101558.10
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr6_+_41139948 0.95 ENSMUST00000103275.4
Trbv17
T cell receptor beta, variable 17
chr4_+_83335947 0.90 ENSMUST00000030206.10
ENSMUST00000071544.11
Snapc3
small nuclear RNA activating complex, polypeptide 3
chr5_+_25452342 0.88 ENSMUST00000114950.2
Galnt11
polypeptide N-acetylgalactosaminyltransferase 11
chr11_+_22462088 0.88 ENSMUST00000059319.8
Tmem17
transmembrane protein 17
chr14_-_52495160 0.86 ENSMUST00000200169.6
Chd8
chromodomain helicase DNA binding protein 8
chr19_+_7394951 0.86 ENSMUST00000159348.3
2700081O15Rik
RIKEN cDNA 2700081O15 gene
chr4_+_136013372 0.83 ENSMUST00000069195.5
ENSMUST00000130658.2
Zfp46
zinc finger protein 46
chr2_+_32460868 0.82 ENSMUST00000140592.8
ENSMUST00000028151.7
Dpm2
dolichol-phosphate (beta-D) mannosyltransferase 2
chr8_+_85696695 0.82 ENSMUST00000164807.2
Prdx2
peroxiredoxin 2
chr16_-_90841360 0.81 ENSMUST00000118522.8
Paxbp1
PAX3 and PAX7 binding protein 1
chr11_+_69737491 0.80 ENSMUST00000019605.4
Plscr3
phospholipid scramblase 3
chr7_-_143102792 0.78 ENSMUST00000072727.7
ENSMUST00000207948.2
ENSMUST00000208190.2
Nap1l4
nucleosome assembly protein 1-like 4
chr11_+_69737437 0.75 ENSMUST00000152566.8
ENSMUST00000108633.9
Plscr3
phospholipid scramblase 3
chr3_+_89072096 0.74 ENSMUST00000121212.9
ENSMUST00000152205.5
ENSMUST00000090927.12
ENSMUST00000148265.8
ENSMUST00000121931.8
Clk2
CDC-like kinase 2
chr17_-_36008863 0.74 ENSMUST00000146472.8
Ddr1
discoidin domain receptor family, member 1
chr15_+_76131020 0.70 ENSMUST00000229380.2
Grina
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr5_+_36050663 0.69 ENSMUST00000064571.11
Afap1
actin filament associated protein 1
chr5_-_136227760 0.66 ENSMUST00000149151.2
ENSMUST00000151786.8
Prkrip1
Prkr interacting protein 1 (IL11 inducible)
chr1_-_55066629 0.62 ENSMUST00000027127.14
Sf3b1
splicing factor 3b, subunit 1
chr18_-_36899245 0.62 ENSMUST00000061522.8
Dnd1
DND microRNA-mediated repression inhibitor 1
chr3_-_95041246 0.61 ENSMUST00000172572.9
ENSMUST00000173462.3
Scnm1
sodium channel modifier 1
chr1_-_64161415 0.60 ENSMUST00000135075.2
Klf7
Kruppel-like factor 7 (ubiquitous)
chr11_+_69737200 0.60 ENSMUST00000108632.8
Plscr3
phospholipid scramblase 3
chr13_-_59930059 0.57 ENSMUST00000225581.2
Gm49354
predicted gene, 49354
chr19_+_34899778 0.51 ENSMUST00000223907.2
Kif20b
kinesin family member 20B
chrX_-_101114906 0.51 ENSMUST00000188731.2
Rtl5
retrotransposon Gag like 5
chr8_+_85696396 0.50 ENSMUST00000109733.8
Prdx2
peroxiredoxin 2
chr1_-_153363354 0.49 ENSMUST00000186380.7
ENSMUST00000188345.2
ENSMUST00000042141.12
Dhx9
DEAH (Asp-Glu-Ala-His) box polypeptide 9
chr17_-_36015496 0.47 ENSMUST00000134995.8
Ddr1
discoidin domain receptor family, member 1
chr19_+_34899752 0.44 ENSMUST00000087341.7
Kif20b
kinesin family member 20B
chr7_+_66393252 0.43 ENSMUST00000066475.11
Cers3
ceramide synthase 3
chr17_+_37504783 0.43 ENSMUST00000038844.7
Ubd
ubiquitin D
chr19_-_4384029 0.41 ENSMUST00000176653.2
Kdm2a
lysine (K)-specific demethylase 2A
chr15_-_84740243 0.39 ENSMUST00000159939.8
Phf21b
PHD finger protein 21B
chr8_+_85696453 0.36 ENSMUST00000125893.8
Prdx2
peroxiredoxin 2
chr16_-_31094095 0.35 ENSMUST00000060188.14
Ppp1r2
protein phosphatase 1, regulatory inhibitor subunit 2
chr8_+_95721378 0.32 ENSMUST00000212956.2
ENSMUST00000212531.2
Adgrg1
adhesion G protein-coupled receptor G1
chr17_+_28794615 0.31 ENSMUST00000232862.2
ENSMUST00000080780.8
Lhfpl5
lipoma HMGIC fusion partner-like 5
chr12_-_75678092 0.31 ENSMUST00000238938.2
Rplp2-ps1
ribosomal protein, large P2, pseudogene 1
chr5_+_110987839 0.31 ENSMUST00000200172.2
ENSMUST00000066160.3
Chek2
checkpoint kinase 2
chr12_-_110662723 0.29 ENSMUST00000021698.13
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr11_+_101333238 0.27 ENSMUST00000107249.8
Rpl27
ribosomal protein L27
chr15_+_76130947 0.27 ENSMUST00000229772.2
ENSMUST00000230347.2
ENSMUST00000023225.8
Grina
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr17_-_79662514 0.27 ENSMUST00000068958.9
Cdc42ep3
CDC42 effector protein (Rho GTPase binding) 3
chr19_+_5790918 0.26 ENSMUST00000081496.6
Ltbp3
latent transforming growth factor beta binding protein 3
chr14_+_102077937 0.22 ENSMUST00000159026.8
Lmo7
LIM domain only 7
chr8_+_95720864 0.21 ENSMUST00000212141.2
Adgrg1
adhesion G protein-coupled receptor G1
chr11_+_101333115 0.21 ENSMUST00000077856.13
Rpl27
ribosomal protein L27
chr7_+_126832399 0.19 ENSMUST00000056232.7
Zfp553
zinc finger protein 553
chr7_+_99115211 0.18 ENSMUST00000037359.9
Klhl35
kelch-like 35
chr3_-_75389047 0.17 ENSMUST00000193989.4
ENSMUST00000203169.3
Wdr49
WD repeat domain 49
chr12_-_110662677 0.15 ENSMUST00000124156.8
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr15_-_5273645 0.15 ENSMUST00000120563.2
Ptger4
prostaglandin E receptor 4 (subtype EP4)
chr8_+_95721019 0.14 ENSMUST00000212976.2
ENSMUST00000212995.2
Adgrg1
adhesion G protein-coupled receptor G1
chr19_-_32080496 0.13 ENSMUST00000235213.2
ENSMUST00000236504.2
Asah2
N-acylsphingosine amidohydrolase 2
chr16_-_13977084 0.12 ENSMUST00000090300.6
Marf1
meiosis regulator and mRNA stability 1
chr8_-_85696040 0.12 ENSMUST00000214133.2
ENSMUST00000147812.8
Gm49661
Rnaseh2a
predicted gene, 49661
ribonuclease H2, large subunit
chr7_+_48895879 0.10 ENSMUST00000064395.13
Nav2
neuron navigator 2
chr6_-_93769426 0.08 ENSMUST00000204788.2
Magi1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr16_+_37909363 0.01 ENSMUST00000023507.13
Gsk3b
glycogen synthase kinase 3 beta
chr7_-_103502404 0.00 ENSMUST00000033229.5
Hbb-y
hemoglobin Y, beta-like embryonic chain

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 5.9 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
1.5 4.4 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553) regulation of intracellular calcium activated chloride channel activity(GO:1902938)
1.1 3.3 GO:0061107 seminal vesicle development(GO:0061107)
1.0 4.2 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.8 10.1 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.7 3.7 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.7 17.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.6 5.1 GO:0005513 detection of calcium ion(GO:0005513)
0.5 5.2 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.4 2.5 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.4 1.6 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.3 6.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.3 2.1 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.3 6.5 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.3 5.0 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.3 1.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.3 0.3 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.2 4.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.2 5.6 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.2 2.7 GO:0035879 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.2 4.5 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.2 1.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.2 2.8 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.2 1.2 GO:0034184 positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) protein localization to site of double-strand break(GO:1990166)
0.2 7.1 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 2.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.2 1.0 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.2 1.4 GO:1990504 dense core granule exocytosis(GO:1990504)
0.2 1.5 GO:0021815 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
0.2 2.9 GO:0070307 lens fiber cell development(GO:0070307)
0.1 0.9 GO:1903436 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.1 1.7 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536)
0.1 1.8 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 1.1 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.8 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 4.8 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.9 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 0.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.9 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.1 3.4 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.1 0.9 GO:0009301 snRNA transcription(GO:0009301)
0.1 0.4 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.1 1.5 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1 4.0 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.1 0.8 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.1 0.4 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 9.3 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.7 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 2.8 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.6 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.4 GO:0070842 aggresome assembly(GO:0070842)
0.0 1.0 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.7 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 6.4 GO:0007416 synapse assembly(GO:0007416)
0.0 2.3 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.7 GO:0048665 neuron fate specification(GO:0048665)
0.0 1.8 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 1.2 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 2.1 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 2.4 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 2.0 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.1 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.0 GO:0051329 interphase(GO:0051325) mitotic interphase(GO:0051329) mitotic cell cycle phase(GO:0098763)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.9 GO:0033269 internode region of axon(GO:0033269)
0.7 6.5 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.2 3.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.2 10.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.2 18.0 GO:0005871 kinesin complex(GO:0005871)
0.2 0.8 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.2 5.1 GO:0097449 astrocyte projection(GO:0097449)
0.2 2.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 4.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 2.5 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 1.5 GO:0044327 dendritic spine head(GO:0044327)
0.1 4.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 7.1 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.0 GO:0097542 ciliary tip(GO:0097542)
0.1 0.5 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 10.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 0.4 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.1 1.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 2.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.9 GO:0036038 MKS complex(GO:0036038)
0.0 5.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 5.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 6.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.6 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.2 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.4 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.9 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 2.5 GO:0030139 endocytic vesicle(GO:0030139)
0.0 2.8 GO:0043204 perikaryon(GO:0043204)
0.0 2.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 2.3 GO:0005882 intermediate filament(GO:0005882)
0.0 4.0 GO:0043209 myelin sheath(GO:0043209)
0.0 9.5 GO:0031252 cell leading edge(GO:0031252)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:0099530 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
1.1 16.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.9 6.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.8 5.5 GO:0004111 creatine kinase activity(GO:0004111)
0.7 5.2 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.7 4.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.6 6.5 GO:0033691 sialic acid binding(GO:0033691)
0.5 4.5 GO:0031849 olfactory receptor binding(GO:0031849)
0.4 1.8 GO:0008502 melatonin receptor activity(GO:0008502)
0.3 2.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 1.2 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.2 2.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2 0.8 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.2 3.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.2 4.4 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.2 7.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 0.5 GO:0033680 ATP-dependent DNA/RNA helicase activity(GO:0033680) triplex DNA binding(GO:0045142)
0.2 5.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 18.0 GO:0003777 microtubule motor activity(GO:0003777)
0.1 3.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 2.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323) cobalt ion binding(GO:0050897)
0.1 1.0 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 1.1 GO:0004568 chitinase activity(GO:0004568)
0.1 1.7 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 3.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.4 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 2.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 2.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.4 GO:0002135 CTP binding(GO:0002135)
0.0 4.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 2.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.9 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 4.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 6.2 GO:0005125 cytokine activity(GO:0005125)
0.0 4.3 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 2.8 GO:0008013 beta-catenin binding(GO:0008013)
0.0 5.1 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.4 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 1.5 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 2.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.7 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 1.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.7 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.1 GO:0004527 exonuclease activity(GO:0004527)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.1 PID ATR PATHWAY ATR signaling pathway
0.1 5.6 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 6.5 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 4.0 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 2.4 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 2.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 4.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 11.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.2 6.2 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.2 5.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 3.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 3.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 2.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 2.5 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.8 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.9 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.0 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 6.3 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins