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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Sox7

Z-value: 0.68

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Transcription factors associated with Sox7

Gene Symbol Gene ID Gene Info
Sox7
ENSMUSG00000063060.7 Sox7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Sox7mm39_v1_chr14_+_64181115_64181136-0.152.0e-01Click!

Activity profile of Sox7 motif

Sorted Z-values of Sox7 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox7

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr3_+_92840279 5.85 ENSMUST00000046234.5
Lce3b
late cornified envelope 3B
chr7_-_14180496 4.33 ENSMUST00000063509.11
Sult2a8
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 8
chr7_-_14180576 4.29 ENSMUST00000125941.3
Sult2a8
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 8
chrX_+_102465616 3.65 ENSMUST00000182089.2
Gm26992
predicted gene, 26992
chr3_+_146302832 3.55 ENSMUST00000029837.14
ENSMUST00000147409.2
ENSMUST00000121133.2
Uox
urate oxidase
chr3_-_69767208 3.54 ENSMUST00000171529.4
ENSMUST00000051239.13
Sptssb
serine palmitoyltransferase, small subunit B
chr1_+_107288928 3.48 ENSMUST00000191425.7
Serpinb11
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11
chr8_-_62576140 3.42 ENSMUST00000034052.14
ENSMUST00000034054.9
Anxa10
annexin A10
chr1_+_107289659 2.97 ENSMUST00000027566.3
Serpinb11
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11
chr1_-_119576347 2.93 ENSMUST00000027632.14
ENSMUST00000187194.2
Epb41l5
erythrocyte membrane protein band 4.1 like 5
chr6_+_48661503 2.89 ENSMUST00000067506.14
ENSMUST00000119575.8
ENSMUST00000121957.8
ENSMUST00000090070.6
Gimap4
GTPase, IMAP family member 4
chr2_-_6134926 2.89 ENSMUST00000126551.2
ENSMUST00000054254.12
ENSMUST00000114942.9
Proser2
proline and serine rich 2
chr2_-_120144622 2.63 ENSMUST00000054651.8
Pla2g4f
phospholipase A2, group IVF
chr3_+_59914164 2.58 ENSMUST00000169794.2
Aadacl2
arylacetamide deacetylase like 2
chr11_-_46280336 2.55 ENSMUST00000020664.13
Itk
IL2 inducible T cell kinase
chr6_+_48661477 2.47 ENSMUST00000118802.8
Gimap4
GTPase, IMAP family member 4
chr12_-_113379925 2.45 ENSMUST00000194162.6
ENSMUST00000192250.2
Ighd
immunoglobulin heavy constant delta
chr11_-_46280298 2.42 ENSMUST00000109237.9
Itk
IL2 inducible T cell kinase
chr2_-_93283024 2.28 ENSMUST00000111257.8
ENSMUST00000145553.8
Cd82
CD82 antigen
chr12_-_75782406 2.28 ENSMUST00000220285.2
Sgpp1
sphingosine-1-phosphate phosphatase 1
chr12_-_75782502 2.23 ENSMUST00000021450.6
Sgpp1
sphingosine-1-phosphate phosphatase 1
chr11_-_46057224 2.10 ENSMUST00000020679.3
Nipal4
NIPA-like domain containing 4
chr6_-_68713748 1.85 ENSMUST00000183936.2
ENSMUST00000196863.2
Igkv19-93
immunoglobulin kappa chain variable 19-93
chr3_-_146302343 1.84 ENSMUST00000029836.9
Dnase2b
deoxyribonuclease II beta
chr16_+_8455538 1.62 ENSMUST00000023396.10
ENSMUST00000230828.2
Pmm2
phosphomannomutase 2
chr11_-_46280281 1.62 ENSMUST00000101306.4
Itk
IL2 inducible T cell kinase
chr6_+_67532481 1.51 ENSMUST00000103302.3
Igkv2-137
immunoglobulin kappa chain variable 2-137
chr3_+_90561560 1.18 ENSMUST00000079286.4
S100a7a
S100 calcium binding protein A7A
chr6_-_99243455 1.17 ENSMUST00000113326.9
Foxp1
forkhead box P1
chr8_+_123829089 1.11 ENSMUST00000000756.6
Rpl13
ribosomal protein L13
chr1_-_173363523 1.08 ENSMUST00000139092.8
Ifi214
interferon activated gene 214
chr3_-_30194559 0.92 ENSMUST00000108271.10
Mecom
MDS1 and EVI1 complex locus
chr7_-_6502647 0.88 ENSMUST00000209055.2
ENSMUST00000207339.4
Olfr1347
olfactory receptor 1347
chr1_-_171476559 0.83 ENSMUST00000111276.9
ENSMUST00000194531.6
Slamf7
SLAM family member 7
chr13_-_4200627 0.81 ENSMUST00000110704.9
ENSMUST00000021635.9
Akr1c18
aldo-keto reductase family 1, member C18
chr1_-_171476495 0.79 ENSMUST00000194791.2
ENSMUST00000192024.6
Slamf7
SLAM family member 7
chr14_+_54433524 0.75 ENSMUST00000103718.2
Traj23
T cell receptor alpha joining 23
chr9_-_111100859 0.74 ENSMUST00000035079.10
Mlh1
mutL homolog 1
chr14_+_54433095 0.74 ENSMUST00000103717.3
Traj24
T cell receptor alpha joining 24
chr2_+_15060051 0.72 ENSMUST00000069870.11
ENSMUST00000239125.2
ENSMUST00000193836.3
Arl5b
ADP-ribosylation factor-like 5B
chr19_-_32085532 0.70 ENSMUST00000236030.2
ENSMUST00000237104.2
ENSMUST00000236208.2
ENSMUST00000235273.2
Asah2
N-acylsphingosine amidohydrolase 2
chr2_-_86640362 0.64 ENSMUST00000216117.2
Olfr141
olfactory receptor 141
chr10_-_107747995 0.56 ENSMUST00000165341.5
Otogl
otogelin-like
chr9_-_36678868 0.53 ENSMUST00000217599.2
ENSMUST00000120381.9
Stt3a
STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)
chr14_+_64890008 0.48 ENSMUST00000224503.2
Kif13b
kinesin family member 13B
chr19_-_12881094 0.45 ENSMUST00000208343.2
ENSMUST00000216989.2
Olfr1447
olfactory receptor 1447
chr2_+_38401655 0.44 ENSMUST00000054234.10
ENSMUST00000112902.8
Nek6
NIMA (never in mitosis gene a)-related expressed kinase 6
chr1_-_136888118 0.43 ENSMUST00000192357.6
ENSMUST00000027649.14
Nr5a2
nuclear receptor subfamily 5, group A, member 2
chr7_-_10488291 0.42 ENSMUST00000226874.2
ENSMUST00000227003.2
ENSMUST00000228561.2
ENSMUST00000228248.2
ENSMUST00000228526.2
ENSMUST00000228098.2
ENSMUST00000227940.2
ENSMUST00000228374.2
ENSMUST00000227702.2
Vmn1r71
vomeronasal 1 receptor 71
chr9_-_35559489 0.37 ENSMUST00000178236.3
Pate3
prostate and testis expressed 3
chr5_-_108022900 0.34 ENSMUST00000138111.8
ENSMUST00000112642.8
Evi5
ecotropic viral integration site 5
chr17_+_38143840 0.28 ENSMUST00000213857.2
Olfr125
olfactory receptor 125
chr2_+_88660081 0.24 ENSMUST00000215929.2
Olfr1205
olfactory receptor 1205
chr7_-_7822866 0.24 ENSMUST00000169683.2
Vmn2r35
vomeronasal 2, receptor 35
chr3_-_151468529 0.21 ENSMUST00000046739.6
Ifi44l
interferon-induced protein 44 like
chr12_-_114793177 0.19 ENSMUST00000103511.2
ENSMUST00000195735.2
Ighv1-31
immunoglobulin heavy variable 1-31
chr7_-_7569785 0.17 ENSMUST00000165921.2
Vmn2r33
vomeronasal 2, receptor 33
chr19_+_13717092 0.13 ENSMUST00000207836.3
Olfr1494
olfactory receptor 1494
chr11_+_73489420 0.11 ENSMUST00000214228.2
Olfr384
olfactory receptor 384
chr9_+_19495807 0.10 ENSMUST00000061693.5
Olfr855
olfactory receptor 855
chr7_-_119078472 0.09 ENSMUST00000209095.2
ENSMUST00000033263.6
ENSMUST00000207261.2
Umod
uromodulin
chr14_+_64889973 0.09 ENSMUST00000100473.5
Kif13b
kinesin family member 13B
chr16_-_58583539 0.09 ENSMUST00000214139.2
Olfr172
olfactory receptor 172
chr14_+_66378382 0.06 ENSMUST00000022620.11
Chrna2
cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal)
chr7_-_106279791 0.05 ENSMUST00000215541.2
Olfr693
olfactory receptor 693
chr7_+_45164042 0.05 ENSMUST00000210868.2
Tulp2
tubby-like protein 2
chr2_-_111104451 0.03 ENSMUST00000214760.2
Olfr1277
olfactory receptor 1277

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.8 4.5 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.4 3.5 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.4 1.6 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.3 6.6 GO:0001865 NK T cell differentiation(GO:0001865)
0.3 0.8 GO:0006714 sesquiterpenoid metabolic process(GO:0006714) response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.2 3.2 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.2 0.5 GO:0043686 co-translational protein modification(GO:0043686)
0.2 3.6 GO:0046415 urate metabolic process(GO:0046415)
0.1 1.2 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 2.1 GO:0015693 magnesium ion transport(GO:0015693)
0.1 2.6 GO:0071236 cellular response to antibiotic(GO:0071236)
0.1 5.8 GO:0018149 peptide cross-linking(GO:0018149)
0.1 1.8 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.1 0.9 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.6 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.4 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 1.6 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.0 5.9 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 3.0 GO:0002377 immunoglobulin production(GO:0002377)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.5 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.2 0.7 GO:0005712 chiasma(GO:0005712) late recombination nodule(GO:0005715)
0.2 2.5 GO:0019815 B cell receptor complex(GO:0019815)
0.1 5.8 GO:0001533 cornified envelope(GO:0001533)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 5.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 6.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 3.6 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.6 GO:0033270 paranode region of axon(GO:0033270)
0.0 1.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.5 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.7 3.5 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.5 1.6 GO:0004615 phosphomannomutase activity(GO:0004615)
0.4 1.8 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.3 2.6 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.3 3.6 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.3 0.8 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.2 0.7 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.1 2.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.7 GO:0017040 ceramidase activity(GO:0017040)
0.1 6.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.5 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 6.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.2 GO:0042056 chemoattractant activity(GO:0042056)
0.0 1.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 2.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 2.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 6.1 GO:0005525 GTP binding(GO:0005525)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.5 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 6.6 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 2.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 4.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 3.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 PID ARF6 PATHWAY Arf6 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 2.6 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 4.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism