PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
Spdef Links Ensembl NCBI MGI UniProt	ENSMUSG00000024215.15	Spdef

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Spdef	mm39_v1_chr17_-_27947863_27947930	0.72	6.8e-13	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr16_+_4825216 Show fit	9.21	ENSMUST00000185147.8	Smim22 Links Ensembl NCBI MGI UniProt Show fit	small integral membrane protein 22
chr7_+_27770655 Show fit	8.83	ENSMUST00000138392.8 ENSMUST00000076648.8	Fcgbp Links Ensembl NCBI MGI UniProt Show fit	Fc fragment of IgG binding protein
chr11_+_69856222 Show fit	8.04	ENSMUST00000018713.13	Cldn7 Links Ensembl NCBI MGI UniProt Show fit	claudin 7
chr16_+_4825170 Show fit	7.89	ENSMUST00000178155.9	Smim22 Links Ensembl NCBI MGI UniProt Show fit	small integral membrane protein 22
chr16_+_4825146 Show fit	7.78	ENSMUST00000184439.8	Smim22 Links Ensembl NCBI MGI UniProt Show fit	small integral membrane protein 22
chr7_+_130633776 Show fit	7.74	ENSMUST00000084509.7 ENSMUST00000213064.3 ENSMUST00000208311.4	Dmbt1 Links Ensembl NCBI MGI UniProt Show fit	deleted in malignant brain tumors 1
chr3_-_90150393 Show fit	7.21	ENSMUST00000107369.2	Creb3l4 Links Ensembl NCBI MGI UniProt Show fit	cAMP responsive element binding protein 3-like 4
chr2_-_119060366 Show fit	7.09	ENSMUST00000076084.6	Ppp1r14d Links Ensembl NCBI MGI UniProt Show fit	protein phosphatase 1, regulatory inhibitor subunit 14D
chr1_+_135746330 Show fit	6.94	ENSMUST00000038760.10	Lad1 Links Ensembl NCBI MGI UniProt Show fit	ladinin
chr8_-_65582206 Show fit	6.88	ENSMUST00000098713.5	Smim31 Links Ensembl NCBI MGI UniProt Show fit	small integral membrane protein 31
chr2_-_119060330 Show fit	6.65	ENSMUST00000110820.3	Ppp1r14d Links Ensembl NCBI MGI UniProt Show fit	protein phosphatase 1, regulatory inhibitor subunit 14D
chr10_+_34359513 Show fit	6.57	ENSMUST00000170771.3	Frk Links Ensembl NCBI MGI UniProt Show fit	fyn-related kinase
chr6_-_86770504 Show fit	6.40	ENSMUST00000204441.3 ENSMUST00000204398.2 ENSMUST00000001187.15	Anxa4 Links Ensembl NCBI MGI UniProt Show fit	annexin A4
chr10_+_34359395 Show fit	6.33	ENSMUST00000019913.15	Frk Links Ensembl NCBI MGI UniProt Show fit	fyn-related kinase
chr9_+_44966464 Show fit	5.93	ENSMUST00000114664.8	Mpzl3 Links Ensembl NCBI MGI UniProt Show fit	myelin protein zero-like 3
chr7_+_19699291 Show fit	5.54	ENSMUST00000094753.6	Ceacam20 Links Ensembl NCBI MGI UniProt Show fit	carcinoembryonic antigen-related cell adhesion molecule 20
chr19_-_11058452 Show fit	5.33	ENSMUST00000025636.8	Ms4a8a Links Ensembl NCBI MGI UniProt Show fit	membrane-spanning 4-domains, subfamily A, member 8A
chr4_+_118384426 Show fit	5.29	ENSMUST00000030261.6	2610528J11Rik Links Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 2610528J11 gene
chr10_-_79369584 Show fit	5.02	ENSMUST00000218241.2 ENSMUST00000166804.2 ENSMUST00000063879.13	Plpp2 Links Ensembl NCBI MGI UniProt Show fit	phospholipid phosphatase 2
chr3_-_30194559 Show fit	4.89	ENSMUST00000108271.10	Mecom Links Ensembl NCBI MGI UniProt Show fit	MDS1 and EVI1 complex locus
chr7_+_140659672 Show fit	4.82	ENSMUST00000066873.5 ENSMUST00000163041.2	Pkp3 Links Ensembl NCBI MGI UniProt Show fit	plakophilin 3
chr4_+_80828883 Show fit	4.64	ENSMUST00000055922.4	Lurap1l Links Ensembl NCBI MGI UniProt Show fit	leucine rich adaptor protein 1-like
chr16_-_21814190 Show fit	4.63	ENSMUST00000231766.2 ENSMUST00000074230.12	Liph Links Ensembl NCBI MGI UniProt Show fit	lipase, member H
chr2_+_129854256 Show fit	4.50	ENSMUST00000110299.3	Tgm3 Links Ensembl NCBI MGI UniProt Show fit	transglutaminase 3, E polypeptide
chr7_+_143027473 Show fit	4.44	ENSMUST00000052348.12	Slc22a18 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 22 (organic cation transporter), member 18
chr4_-_130172998 Show fit	4.31	ENSMUST00000120126.9	Serinc2 Links Ensembl NCBI MGI UniProt Show fit	serine incorporator 2
chr3_-_84489923 Show fit	4.29	ENSMUST00000143514.3	Arfip1 Links Ensembl NCBI MGI UniProt Show fit	ADP-ribosylation factor interacting protein 1
chr15_-_99717956 Show fit	4.23	ENSMUST00000109024.9	Lima1 Links Ensembl NCBI MGI UniProt Show fit	LIM domain and actin binding 1
chr4_+_118384183 Show fit	4.17	ENSMUST00000106367.8	2610528J11Rik Links Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 2610528J11 gene
chr3_+_27992787 Show fit	4.10	ENSMUST00000120834.8	Pld1 Links Ensembl NCBI MGI UniProt Show fit	phospholipase D1
chr6_-_72367642 Show fit	4.01	ENSMUST00000059983.10	Vamp8 Links Ensembl NCBI MGI UniProt Show fit	vesicle-associated membrane protein 8
chr9_-_50657800 Show fit	3.95	ENSMUST00000239417.2 ENSMUST00000034564.4	2310030G06Rik Links Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 2310030G06 gene
chr16_-_21814289 Show fit	3.95	ENSMUST00000060673.8	Liph Links Ensembl NCBI MGI UniProt Show fit	lipase, member H
chr7_-_25315299 Show fit	3.90	ENSMUST00000098663.4 ENSMUST00000238895.2	Erich4 Links Ensembl NCBI MGI UniProt Show fit	glutamate rich 4
chr17_+_32755525 Show fit	3.70	ENSMUST00000169591.8 ENSMUST00000003416.15	Cyp4f16 Links Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 4, subfamily f, polypeptide 16
chr15_-_34679321 Show fit	3.42	ENSMUST00000040791.9	Nipal2 Links Ensembl NCBI MGI UniProt Show fit	NIPA-like domain containing 2
chr1_+_58841650 Show fit	3.34	ENSMUST00000165549.8	Casp8 Links Ensembl NCBI MGI UniProt Show fit	caspase 8
chr1_+_58841808 Show fit	3.23	ENSMUST00000190213.2	Casp8 Links Ensembl NCBI MGI UniProt Show fit	caspase 8
chr15_+_78912642 Show fit	3.23	ENSMUST00000180086.3	H1f0 Links Ensembl NCBI MGI UniProt Show fit	H1.0 linker histone
chr6_-_87327885 Show fit	3.19	ENSMUST00000032129.3	Gkn1 Links Ensembl NCBI MGI UniProt Show fit	gastrokine 1
chr13_-_58532990 Show fit	3.16	ENSMUST00000022032.7	2210016F16Rik Links Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 2210016F16 gene
chr11_-_105835238 Show fit	3.14	ENSMUST00000019734.11 ENSMUST00000184269.3 ENSMUST00000150563.3	Cyb561 Links Ensembl NCBI MGI UniProt Show fit	cytochrome b-561
chr2_-_120144622 Show fit	3.10	ENSMUST00000054651.8	Pla2g4f Links Ensembl NCBI MGI UniProt Show fit	phospholipase A2, group IVF
chr17_+_35268942 Show fit	2.98	ENSMUST00000007257.10	Clic1 Links Ensembl NCBI MGI UniProt Show fit	chloride intracellular channel 1
chr8_+_72914966 Show fit	2.96	ENSMUST00000003121.9	Rab8a Links Ensembl NCBI MGI UniProt Show fit	RAB8A, member RAS oncogene family
chr2_-_92290791 Show fit	2.95	ENSMUST00000125276.2	Slc35c1 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 35, member C1
chr2_+_57887896 Show fit	2.94	ENSMUST00000112616.8 ENSMUST00000166729.2	Galnt5 Links Ensembl NCBI MGI UniProt Show fit	polypeptide N-acetylgalactosaminyltransferase 5
chr3_-_84489783 Show fit	2.88	ENSMUST00000107687.9 ENSMUST00000098990.10	Arfip1 Links Ensembl NCBI MGI UniProt Show fit	ADP-ribosylation factor interacting protein 1
chr17_-_56312555 Show fit	2.87	ENSMUST00000043785.8	Stap2 Links Ensembl NCBI MGI UniProt Show fit	signal transducing adaptor family member 2
chr14_+_55909816 Show fit	2.84	ENSMUST00000227178.2 ENSMUST00000227914.2	Gmpr2 Links Ensembl NCBI MGI UniProt Show fit	guanosine monophosphate reductase 2
chr7_-_30672747 Show fit	2.80	ENSMUST00000205961.2	Lsr Links Ensembl NCBI MGI UniProt Show fit	lipolysis stimulated lipoprotein receptor
chr12_-_114579938 Show fit	2.76	ENSMUST00000195469.6 ENSMUST00000109711.4	Ighv1-12 Links Ensembl NCBI MGI UniProt Show fit	immunoglobulin heavy variable V1-12
chr14_-_54491365 Show fit	2.66	ENSMUST00000128231.2	Dad1 Links Ensembl NCBI MGI UniProt Show fit	defender against cell death 1
chr18_+_35860019 Show fit	2.65	ENSMUST00000097617.3	1700066B19Rik Links Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 1700066B19 gene
chr3_-_89300936 Show fit	2.62	ENSMUST00000124783.8 ENSMUST00000126027.8	Zbtb7b Links Ensembl NCBI MGI UniProt Show fit	zinc finger and BTB domain containing 7B
chr18_+_67338437 Show fit	2.62	ENSMUST00000210564.3	Chmp1b Links Ensembl NCBI MGI UniProt Show fit	charged multivesicular body protein 1B
chr14_-_55344004 Show fit	2.59	ENSMUST00000036041.15	Ap1g2 Links Ensembl NCBI MGI UniProt Show fit	adaptor protein complex AP-1, gamma 2 subunit
chr14_+_55909692 Show fit	2.58	ENSMUST00000002397.7	Gmpr2 Links Ensembl NCBI MGI UniProt Show fit	guanosine monophosphate reductase 2
chr3_+_90448453 Show fit	2.54	ENSMUST00000107333.8 ENSMUST00000107331.8 ENSMUST00000098910.3	S100a16 Links Ensembl NCBI MGI UniProt Show fit	S100 calcium binding protein A16
chr16_-_56533179 Show fit	2.53	ENSMUST00000136394.8	Tfg Links Ensembl NCBI MGI UniProt Show fit	Trk-fused gene
chr19_-_38032006 Show fit	2.50	ENSMUST00000172095.3 ENSMUST00000041475.16	Myof Links Ensembl NCBI MGI UniProt Show fit	myoferlin
chr12_+_80691275 Show fit	2.50	ENSMUST00000217889.2	Slc39a9 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 39 (zinc transporter), member 9
chr5_+_115680964 Show fit	2.50	ENSMUST00000137716.8	Pxn Links Ensembl NCBI MGI UniProt Show fit	paxillin
chr6_-_119365632 Show fit	2.48	ENSMUST00000169744.8	Adipor2 Links Ensembl NCBI MGI UniProt Show fit	adiponectin receptor 2
chr17_+_27276262 Show fit	2.44	ENSMUST00000049308.9	Itpr3 Links Ensembl NCBI MGI UniProt Show fit	inositol 1,4,5-triphosphate receptor 3
chr6_-_95695781 Show fit	2.39	ENSMUST00000204224.3	Suclg2 Links Ensembl NCBI MGI UniProt Show fit	succinate-Coenzyme A ligase, GDP-forming, beta subunit
chr12_+_80690985 Show fit	2.39	ENSMUST00000219405.2 ENSMUST00000085245.7	Slc39a9 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 39 (zinc transporter), member 9
chrX_+_36059274 Show fit	2.37	ENSMUST00000016463.4	Slc25a5 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5
chr8_+_106032205 Show fit	2.34	ENSMUST00000109375.4 ENSMUST00000212033.2	Elmo3 Links Ensembl NCBI MGI UniProt Show fit	engulfment and cell motility 3
chr8_+_121854566 Show fit	2.28	ENSMUST00000181609.2	Foxl1 Links Ensembl NCBI MGI UniProt Show fit	forkhead box L1
chr9_-_22042930 Show fit	2.27	ENSMUST00000213815.2	Acp5 Links Ensembl NCBI MGI UniProt Show fit	acid phosphatase 5, tartrate resistant
chr3_-_108053396 Show fit	2.25	ENSMUST00000000001.5	Gnai3 Links Ensembl NCBI MGI UniProt Show fit	guanine nucleotide binding protein (G protein), alpha inhibiting 3
chr10_-_128657445 Show fit	2.23	ENSMUST00000217685.2 ENSMUST00000026409.5 ENSMUST00000219215.2 ENSMUST00000219524.2	Ormdl2 Links Ensembl NCBI MGI UniProt Show fit	ORM1-like 2 (S. cerevisiae)
chr13_-_104057016 Show fit	2.22	ENSMUST00000022222.12	Erbin Links Ensembl NCBI MGI UniProt Show fit	Erbb2 interacting protein
chr1_+_57884693 Show fit	2.20	ENSMUST00000169772.3	Spats2l Links Ensembl NCBI MGI UniProt Show fit	spermatogenesis associated, serine-rich 2-like
chr19_+_8975249 Show fit	2.20	ENSMUST00000236390.2	Ahnak Links Ensembl NCBI MGI UniProt Show fit	AHNAK nucleoprotein (desmoyokin)
chr19_-_5156995 Show fit	2.17	ENSMUST00000237438.2 ENSMUST00000236149.2 ENSMUST00000025804.7	Rab1b Links Ensembl NCBI MGI UniProt Show fit	RAB1B, member RAS oncogene family
chr9_+_80072361 Show fit	2.13	ENSMUST00000184480.8	Myo6 Links Ensembl NCBI MGI UniProt Show fit	myosin VI
chr8_+_72973560 Show fit	2.12	ENSMUST00000003123.10	Fam32a Links Ensembl NCBI MGI UniProt Show fit	family with sequence similarity 32, member A
chr19_-_38031774 Show fit	2.10	ENSMUST00000226068.2	Myof Links Ensembl NCBI MGI UniProt Show fit	myoferlin
chr3_-_89300599 Show fit	2.09	ENSMUST00000142119.2 ENSMUST00000029677.9 ENSMUST00000148361.8	Zbtb7b Links Ensembl NCBI MGI UniProt Show fit	zinc finger and BTB domain containing 7B
chr12_+_76593799 Show fit	2.06	ENSMUST00000218380.2 ENSMUST00000219751.2	Plekhg3 Links Ensembl NCBI MGI UniProt Show fit	pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr4_-_155141241 Show fit	2.03	ENSMUST00000131173.3	Plch2 Links Ensembl NCBI MGI UniProt Show fit	phospholipase C, eta 2
chr12_-_114579763 Show fit	1.97	ENSMUST00000103500.2	Ighv1-12 Links Ensembl NCBI MGI UniProt Show fit	immunoglobulin heavy variable V1-12
chr15_+_94441486 Show fit	1.95	ENSMUST00000074936.10	Irak4 Links Ensembl NCBI MGI UniProt Show fit	interleukin-1 receptor-associated kinase 4
chr3_-_5641171 Show fit	1.92	ENSMUST00000071280.8 ENSMUST00000195855.6 ENSMUST00000165309.8 ENSMUST00000164828.8	Pex2 Links Ensembl NCBI MGI UniProt Show fit	peroxisomal biogenesis factor 2
chr7_-_79882228 Show fit	1.91	ENSMUST00000123279.8	Cib1 Links Ensembl NCBI MGI UniProt Show fit	calcium and integrin binding 1 (calmyrin)
chr7_+_28580847 Show fit	1.90	ENSMUST00000066880.6	Capn12 Links Ensembl NCBI MGI UniProt Show fit	calpain 12
chr2_-_34262012 Show fit	1.86	ENSMUST00000113132.9 ENSMUST00000040638.15	Pbx3 Links Ensembl NCBI MGI UniProt Show fit	pre B cell leukemia homeobox 3
chr4_-_107780716 Show fit	1.86	ENSMUST00000106719.8 ENSMUST00000106720.9 ENSMUST00000131644.2 ENSMUST00000030345.15	Cpt2 Links Ensembl NCBI MGI UniProt Show fit	carnitine palmitoyltransferase 2
chr13_+_41040657 Show fit	1.85	ENSMUST00000069958.15	Gcnt2 Links Ensembl NCBI MGI UniProt Show fit	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr11_-_75828551 Show fit	1.82	ENSMUST00000121287.8	Rph3al Links Ensembl NCBI MGI UniProt Show fit	rabphilin 3A-like (without C2 domains)
chr3_-_5641295 Show fit	1.82	ENSMUST00000059021.10	Pex2 Links Ensembl NCBI MGI UniProt Show fit	peroxisomal biogenesis factor 2
chr8_+_124059414 Show fit	1.82	ENSMUST00000010298.7	Spire2 Links Ensembl NCBI MGI UniProt Show fit	spire type actin nucleation factor 2
chr15_-_36609812 Show fit	1.81	ENSMUST00000226496.2	Pabpc1 Links Ensembl NCBI MGI UniProt Show fit	poly(A) binding protein, cytoplasmic 1
chr3_+_95801325 Show fit	1.81	ENSMUST00000197081.2 ENSMUST00000056710.10	Aph1a Links Ensembl NCBI MGI UniProt Show fit	aph1 homolog A, gamma secretase subunit
chr2_-_52632178 Show fit	1.80	ENSMUST00000102759.8 ENSMUST00000127316.8	Stam2 Links Ensembl NCBI MGI UniProt Show fit	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chr9_+_80072274 Show fit	1.80	ENSMUST00000035889.15 ENSMUST00000113268.8	Myo6 Links Ensembl NCBI MGI UniProt Show fit	myosin VI
chr9_-_110305705 Show fit	1.79	ENSMUST00000198164.5 ENSMUST00000068025.13	Klhl18 Links Ensembl NCBI MGI UniProt Show fit	kelch-like 18
chrX_-_72759748 Show fit	1.77	ENSMUST00000002091.6	Bcap31 Links Ensembl NCBI MGI UniProt Show fit	B cell receptor associated protein 31
chr2_-_167334746 Show fit	1.76	ENSMUST00000109211.9 ENSMUST00000057627.16	Spata2 Links Ensembl NCBI MGI UniProt Show fit	spermatogenesis associated 2
chr11_-_103254257 Show fit	1.76	ENSMUST00000092557.6	Arhgap27 Links Ensembl NCBI MGI UniProt Show fit	Rho GTPase activating protein 27
chr11_-_69576363 Show fit	1.72	ENSMUST00000018896.14	Tnfsf13 Links Ensembl NCBI MGI UniProt Show fit	tumor necrosis factor (ligand) superfamily, member 13
chr17_+_28491085 Show fit	1.68	ENSMUST00000169040.3	Ppard Links Ensembl NCBI MGI UniProt Show fit	peroxisome proliferator activator receptor delta
chr3_-_79536166 Show fit	1.67	ENSMUST00000029386.14	Etfdh Links Ensembl NCBI MGI UniProt Show fit	electron transferring flavoprotein, dehydrogenase
chr3_-_14843512 Show fit	1.66	ENSMUST00000094365.11	Car1 Links Ensembl NCBI MGI UniProt Show fit	carbonic anhydrase 1
chr6_+_14901343 Show fit	1.66	ENSMUST00000115477.8	Foxp2 Links Ensembl NCBI MGI UniProt Show fit	forkhead box P2
chr7_+_27828855 Show fit	1.65	ENSMUST00000059886.12	9530053A07Rik Links Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 9530053A07 gene
chr7_-_79882313 Show fit	1.65	ENSMUST00000206084.2 ENSMUST00000205996.2 ENSMUST00000071457.12	Cib1 Links Ensembl NCBI MGI UniProt Show fit	calcium and integrin binding 1 (calmyrin)
chr11_-_70545424 Show fit	1.64	ENSMUST00000108549.2	Pfn1 Links Ensembl NCBI MGI UniProt Show fit	profilin 1
chr14_-_55909314 Show fit	1.61	ENSMUST00000163750.8	Nedd8 Links Ensembl NCBI MGI UniProt Show fit	neural precursor cell expressed, developmentally down-regulated gene 8
chr3_+_95801263 Show fit	1.60	ENSMUST00000015894.12	Aph1a Links Ensembl NCBI MGI UniProt Show fit	aph1 homolog A, gamma secretase subunit
chr11_+_105866030 Show fit	1.58	ENSMUST00000001964.8	Ace Links Ensembl NCBI MGI UniProt Show fit	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr5_+_115681003 Show fit	1.58	ENSMUST00000157050.8	Pxn Links Ensembl NCBI MGI UniProt Show fit	paxillin
chr18_+_77861656 Show fit	1.57	ENSMUST00000114748.2	Atp5a1 Links Ensembl NCBI MGI UniProt Show fit	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1
chr13_-_42000958 Show fit	1.56	ENSMUST00000072012.10	Adtrp Links Ensembl NCBI MGI UniProt Show fit	androgen dependent TFPI regulating protein
chr13_-_60325170 Show fit	1.55	ENSMUST00000065086.6	Gas1 Links Ensembl NCBI MGI UniProt Show fit	growth arrest specific 1
chr11_-_70545450 Show fit	1.54	ENSMUST00000018437.3	Pfn1 Links Ensembl NCBI MGI UniProt Show fit	profilin 1
chr11_+_20151406 Show fit	1.53	ENSMUST00000020358.12 ENSMUST00000109602.8 ENSMUST00000109601.8 ENSMUST00000163483.2	Rab1a Links Ensembl NCBI MGI UniProt Show fit	RAB1A, member RAS oncogene family
chr8_-_84059048 Show fit	1.51	ENSMUST00000177594.8 ENSMUST00000053902.4	Elmod2 Links Ensembl NCBI MGI UniProt Show fit	ELMO/CED-12 domain containing 2
chr13_-_74882328 Show fit	1.50	ENSMUST00000223309.2	Cast Links Ensembl NCBI MGI UniProt Show fit	calpastatin
chr8_+_3637785 Show fit	1.46	ENSMUST00000171962.3 ENSMUST00000207712.2 ENSMUST00000207970.2 ENSMUST00000207533.2 ENSMUST00000208240.2 ENSMUST00000207432.2 ENSMUST00000207077.2	Camsap3 Links Ensembl NCBI MGI UniProt Show fit	calmodulin regulated spectrin-associated protein family, member 3
chr13_-_74956924 Show fit	1.45	ENSMUST00000223206.2	Cast Links Ensembl NCBI MGI UniProt Show fit	calpastatin
chr14_+_28233301 Show fit	1.44	ENSMUST00000112272.2	Wnt5a Links Ensembl NCBI MGI UniProt Show fit	wingless-type MMTV integration site family, member 5A
chr2_-_127383305 Show fit	1.41	ENSMUST00000103214.3	Prom2 Links Ensembl NCBI MGI UniProt Show fit	prominin 2
chr4_+_101504909 Show fit	1.41	ENSMUST00000030254.15	Leprot Links Ensembl NCBI MGI UniProt Show fit	leptin receptor overlapping transcript
chr17_-_33166362 Show fit	1.40	ENSMUST00000234083.2 ENSMUST00000075253.13	Cyp4f13 Links Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 4, subfamily f, polypeptide 13
chr16_+_19578981 Show fit	1.40	ENSMUST00000079780.10 ENSMUST00000164397.8	B3gnt5 Links Ensembl NCBI MGI UniProt Show fit	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr16_-_43836681 Show fit	1.39	ENSMUST00000036174.10	Gramd1c Links Ensembl NCBI MGI UniProt Show fit	GRAM domain containing 1C
chr17_-_25394445 Show fit	1.39	ENSMUST00000224277.2	Percc1 Links Ensembl NCBI MGI UniProt Show fit	proline and glutamate rich with coiled coil 1
chr14_-_55909527 Show fit	1.38	ENSMUST00000010520.10	Nedd8 Links Ensembl NCBI MGI UniProt Show fit	neural precursor cell expressed, developmentally down-regulated gene 8
chr3_+_85946145 Show fit	1.38	ENSMUST00000238331.2	Sh3d19 Links Ensembl NCBI MGI UniProt Show fit	SH3 domain protein D19
chr3_-_122778052 Show fit	1.38	ENSMUST00000199401.2 ENSMUST00000197314.5 ENSMUST00000197934.5 ENSMUST00000090379.7	Usp53 Links Ensembl NCBI MGI UniProt Show fit	ubiquitin specific peptidase 53
chr11_+_72686990 Show fit	1.36	ENSMUST00000069395.7 ENSMUST00000172220.8	Zzef1 Links Ensembl NCBI MGI UniProt Show fit	zinc finger, ZZ-type with EF hand domain 1
chr13_-_74882374 Show fit	1.36	ENSMUST00000220738.2	Cast Links Ensembl NCBI MGI UniProt Show fit	calpastatin
chr18_-_46730547 Show fit	1.35	ENSMUST00000151189.2	Tmed7 Links Ensembl NCBI MGI UniProt Show fit	transmembrane p24 trafficking protein 7
chr11_+_72687080 Show fit	1.35	ENSMUST00000207107.2	Zzef1 Links Ensembl NCBI MGI UniProt Show fit	zinc finger, ZZ-type with EF hand domain 1
chr18_-_73836810 Show fit	1.34	ENSMUST00000025393.14	Smad4 Links Ensembl NCBI MGI UniProt Show fit	SMAD family member 4
chr17_+_26895344 Show fit	1.33	ENSMUST00000015719.16	Atp6v0e Links Ensembl NCBI MGI UniProt Show fit	ATPase, H+ transporting, lysosomal V0 subunit E
chr15_-_78687216 Show fit	1.32	ENSMUST00000164826.8	Card10 Links Ensembl NCBI MGI UniProt Show fit	caspase recruitment domain family, member 10
chr18_-_46730381 Show fit	1.31	ENSMUST00000036030.14	Tmed7 Links Ensembl NCBI MGI UniProt Show fit	transmembrane p24 trafficking protein 7
chrX_-_133177717 Show fit	1.30	ENSMUST00000087541.12 ENSMUST00000087540.4	Trmt2b Links Ensembl NCBI MGI UniProt Show fit	TRM2 tRNA methyltransferase 2B
chr16_+_19578945 Show fit	1.30	ENSMUST00000121344.8	B3gnt5 Links Ensembl NCBI MGI UniProt Show fit	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr2_+_145627900 Show fit	1.28	ENSMUST00000110005.8 ENSMUST00000094480.11	Rin2 Links Ensembl NCBI MGI UniProt Show fit	Ras and Rab interactor 2
chrX_+_74460275 Show fit	1.26	ENSMUST00000118428.8 ENSMUST00000114074.8 ENSMUST00000133781.8	Brcc3 Links Ensembl NCBI MGI UniProt Show fit	BRCA1/BRCA2-containing complex, subunit 3
chr7_+_28140450 Show fit	1.26	ENSMUST00000135686.2	Gmfg Links Ensembl NCBI MGI UniProt Show fit	glia maturation factor, gamma
chr19_+_5118103 Show fit	1.24	ENSMUST00000070630.8	Cd248 Links Ensembl NCBI MGI UniProt Show fit	CD248 antigen, endosialin
chr16_-_94171853 Show fit	1.23	ENSMUST00000113914.8 ENSMUST00000113905.8	Pigp Links Ensembl NCBI MGI UniProt Show fit	phosphatidylinositol glycan anchor biosynthesis, class P
chr8_-_73324877 Show fit	1.22	ENSMUST00000058733.9 ENSMUST00000167290.8	Smim7 Links Ensembl NCBI MGI UniProt Show fit	small integral membrane protein 7
chr11_-_86574586 Show fit	1.21	ENSMUST00000018315.10	Vmp1 Links Ensembl NCBI MGI UniProt Show fit	vacuole membrane protein 1
chr7_-_141241632 Show fit	1.20	ENSMUST00000239500.1	ENSMUSG00000118661.1 Links Ensembl NCBI MGI UniProt Show fit	mucin 6, gastric
chr2_-_127383332 Show fit	1.20	ENSMUST00000028855.14	Prom2 Links Ensembl NCBI MGI UniProt Show fit	prominin 2
chr6_-_129449739 Show fit	1.19	ENSMUST00000112076.9 ENSMUST00000184581.3	Clec7a Links Ensembl NCBI MGI UniProt Show fit	C-type lectin domain family 7, member a
chr11_-_75828504 Show fit	1.16	ENSMUST00000108420.9	Rph3al Links Ensembl NCBI MGI UniProt Show fit	rabphilin 3A-like (without C2 domains)
chr10_+_17598961 Show fit	1.16	ENSMUST00000038107.9 ENSMUST00000219558.2 ENSMUST00000218370.2	Cited2 Links Ensembl NCBI MGI UniProt Show fit	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr15_-_54141816 Show fit	1.16	ENSMUST00000079772.4	Tnfrsf11b Links Ensembl NCBI MGI UniProt Show fit	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
chr12_+_33004178 Show fit	1.16	ENSMUST00000020885.13	Sypl Links Ensembl NCBI MGI UniProt Show fit	synaptophysin-like protein
chr8_-_70962972 Show fit	1.15	ENSMUST00000140679.8 ENSMUST00000129909.8 ENSMUST00000081940.11	Uba52 Links Ensembl NCBI MGI UniProt Show fit	ubiquitin A-52 residue ribosomal protein fusion product 1
chr16_-_92622972 Show fit	1.15	ENSMUST00000023673.14	Runx1 Links Ensembl NCBI MGI UniProt Show fit	runt related transcription factor 1
chr2_+_25132941 Show fit	1.14	ENSMUST00000114355.2 ENSMUST00000060818.2	Rnf208 Links Ensembl NCBI MGI UniProt Show fit	ring finger protein 208
chr19_-_17316906 Show fit	1.13	ENSMUST00000169897.2	Gcnt1 Links Ensembl NCBI MGI UniProt Show fit	glucosaminyl (N-acetyl) transferase 1, core 2
chr3_+_93052089 Show fit	1.12	ENSMUST00000107300.7 ENSMUST00000195515.2	Crnn Links Ensembl NCBI MGI UniProt Show fit	cornulin
chr3_+_87826834 Show fit	1.12	ENSMUST00000137775.2	Mrpl24 Links Ensembl NCBI MGI UniProt Show fit	mitochondrial ribosomal protein L24
chr13_-_21900313 Show fit	1.11	ENSMUST00000091756.2	H2bc13 Links Ensembl NCBI MGI UniProt Show fit	H2B clustered histone 13
chr3_-_79535966 Show fit	1.11	ENSMUST00000120992.8	Etfdh Links Ensembl NCBI MGI UniProt Show fit	electron transferring flavoprotein, dehydrogenase
chr1_-_13660027 Show fit	1.10	ENSMUST00000027068.11	Tram1 Links Ensembl NCBI MGI UniProt Show fit	translocating chain-associating membrane protein 1
chr6_+_29348068 Show fit	1.10	ENSMUST00000173216.8 ENSMUST00000173694.5 ENSMUST00000172974.8 ENSMUST00000031779.17 ENSMUST00000090481.14	Calu Links Ensembl NCBI MGI UniProt Show fit	calumenin
chr4_-_156312996 Show fit	1.10	ENSMUST00000105571.4	Plekhn1 Links Ensembl NCBI MGI UniProt Show fit	pleckstrin homology domain containing, family N member 1
chrX_+_99669343 Show fit	1.10	ENSMUST00000048962.4	Kif4 Links Ensembl NCBI MGI UniProt Show fit	kinesin family member 4
chr11_-_70537878 Show fit	1.10	ENSMUST00000014750.15	Slc25a11 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11
chr3_+_122039274 Show fit	1.09	ENSMUST00000178826.8	Gclm Links Ensembl NCBI MGI UniProt Show fit	glutamate-cysteine ligase, modifier subunit
chr1_+_151631203 Show fit	1.08	ENSMUST00000187951.7 ENSMUST00000191070.2	Edem3 Links Ensembl NCBI MGI UniProt Show fit	ER degradation enhancer, mannosidase alpha-like 3
chr5_+_124577952 Show fit	1.08	ENSMUST00000059580.11	Kmt5a Links Ensembl NCBI MGI UniProt Show fit	lysine methyltransferase 5A
chr19_-_4665509 Show fit	1.08	ENSMUST00000053597.3	Lrfn4 Links Ensembl NCBI MGI UniProt Show fit	leucine rich repeat and fibronectin type III domain containing 4
chr10_-_80156337 Show fit	1.08	ENSMUST00000020341.9	2310011J03Rik Links Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 2310011J03 gene
chr7_+_86895851 Show fit	1.07	ENSMUST00000032781.14	Nox4 Links Ensembl NCBI MGI UniProt Show fit	NADPH oxidase 4
chr11_+_97917520 Show fit	1.07	ENSMUST00000092425.11	Rpl19 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein L19
chr11_+_101144533 Show fit	1.07	ENSMUST00000007533.15 ENSMUST00000042477.13 ENSMUST00000100414.12 ENSMUST00000107280.11 ENSMUST00000121331.2	Vps25 Links Ensembl NCBI MGI UniProt Show fit	vacuolar protein sorting 25
chr4_+_101504938 Show fit	1.06	ENSMUST00000106927.2	Leprot Links Ensembl NCBI MGI UniProt Show fit	leptin receptor overlapping transcript
chr7_+_28140352 Show fit	1.05	ENSMUST00000078845.13	Gmfg Links Ensembl NCBI MGI UniProt Show fit	glia maturation factor, gamma
chr11_-_55202969 Show fit	1.05	ENSMUST00000108864.2	Fat2 Links Ensembl NCBI MGI UniProt Show fit	FAT atypical cadherin 2
chr2_+_6327431 Show fit	1.05	ENSMUST00000114937.8	Usp6nl Links Ensembl NCBI MGI UniProt Show fit	USP6 N-terminal like
chr15_-_78413780 Show fit	1.02	ENSMUST00000229185.2	C1qtnf6 Links Ensembl NCBI MGI UniProt Show fit	C1q and tumor necrosis factor related protein 6
chr7_+_3706992 Show fit	1.01	ENSMUST00000006496.15 ENSMUST00000108623.8 ENSMUST00000139818.2 ENSMUST00000108625.8	Rps9 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein S9
chr5_-_31065036 Show fit	1.01	ENSMUST00000132034.5 ENSMUST00000132253.5	Ost4 Links Ensembl NCBI MGI UniProt Show fit	oligosaccharyltransferase complex subunit 4 (non-catalytic)
chrX_+_74460234 Show fit	1.01	ENSMUST00000033544.14	Brcc3 Links Ensembl NCBI MGI UniProt Show fit	BRCA1/BRCA2-containing complex, subunit 3
chrX_-_133177638 Show fit	1.00	ENSMUST00000113252.8	Trmt2b Links Ensembl NCBI MGI UniProt Show fit	TRM2 tRNA methyltransferase 2B
chr4_-_62326853 Show fit	0.99	ENSMUST00000107459.2 ENSMUST00000084525.12	Cdc26 Links Ensembl NCBI MGI UniProt Show fit	cell division cycle 26
chr1_+_39406897 Show fit	0.98	ENSMUST00000086535.12	Rpl31 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein L31
chr12_+_76118790 Show fit	0.98	ENSMUST00000131480.8	Syne2 Links Ensembl NCBI MGI UniProt Show fit	spectrin repeat containing, nuclear envelope 2
chr12_+_86129329 Show fit	0.97	ENSMUST00000054565.8 ENSMUST00000222821.2 ENSMUST00000222905.2	Ift43 Links Ensembl NCBI MGI UniProt Show fit	intraflagellar transport 43
chr17_-_24746804 Show fit	0.97	ENSMUST00000176353.8 ENSMUST00000176237.8	Traf7 Links Ensembl NCBI MGI UniProt Show fit	TNF receptor-associated factor 7
chr2_+_152511381 Show fit	0.96	ENSMUST00000125366.8 ENSMUST00000109825.8 ENSMUST00000089059.9 ENSMUST00000079247.4	H13 Links Ensembl NCBI MGI UniProt Show fit	histocompatibility 13
chr18_+_31742565 Show fit	0.95	ENSMUST00000164667.2	B930094E09Rik Links Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA B930094E09 gene
chr9_+_114517812 Show fit	0.95	ENSMUST00000047404.7	Dync1li1 Links Ensembl NCBI MGI UniProt Show fit	dynein cytoplasmic 1 light intermediate chain 1
chr1_+_39406979 Show fit	0.93	ENSMUST00000178079.8 ENSMUST00000179954.8	Rpl31 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein L31
chr11_+_81926394 Show fit	0.93	ENSMUST00000000193.6	Ccl2 Links Ensembl NCBI MGI UniProt Show fit	chemokine (C-C motif) ligand 2
chr9_-_113537277 Show fit	0.93	ENSMUST00000111861.4 ENSMUST00000035086.13	Pdcd6ip Links Ensembl NCBI MGI UniProt Show fit	programmed cell death 6 interacting protein
chr16_-_43800109 Show fit	0.92	ENSMUST00000231700.2	Zdhhc23 Links Ensembl NCBI MGI UniProt Show fit	zinc finger, DHHC domain containing 23
chr12_+_73631562 Show fit	0.91	ENSMUST00000021527.15	Prkch Links Ensembl NCBI MGI UniProt Show fit	protein kinase C, eta

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.8	5.4	GO:0046038	GMP catabolic process(GO:0046038)
1.2	4.7	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
1.0	4.0	GO:0090187	autophagosome docking(GO:0016240) zymogen granule exocytosis(GO:0070625) positive regulation of pancreatic juice secretion(GO:0090187)
1.0	1.0	GO:1904211	membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.9	2.8	GO:1904274	tricellular tight junction assembly(GO:1904274)
0.9	0.9	GO:0090264	immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265)
0.9	3.6	GO:0007113	endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
0.8	4.8	GO:0002159	desmosome assembly(GO:0002159)
0.8	2.3	GO:0071846	actin filament debranching(GO:0071846)
0.7	6.4	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
0.7	2.6	GO:2001287	negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.6	4.3	GO:1904219	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.6	1.8	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.6	1.7	GO:0002426	immunoglobulin production in mucosal tissue(GO:0002426)
0.6	2.3	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.6	2.3	GO:0070537	histone H2A K63-linked deubiquitination(GO:0070537)
0.6	2.2	GO:1900060	negative regulation of ceramide biosynthetic process(GO:1900060)
0.5	1.6	GO:2000170	positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.5	3.4	GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.5	1.4	GO:0061347	chemorepulsion of dopaminergic neuron axon(GO:0036518) cervix development(GO:0060067) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) melanocyte proliferation(GO:0097325) regulation of cell proliferation in midbrain(GO:1904933)
0.5	6.6	GO:0036462	TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.5	1.8	GO:0070649	formin-nucleated actin cable assembly(GO:0070649)
0.5	1.4	GO:2000395	regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.4	1.3	GO:2000793	left ventricular cardiac muscle tissue morphogenesis(GO:0003220) nephrogenic mesenchyme development(GO:0072076) cell proliferation involved in heart valve development(GO:2000793)
0.4	2.2	GO:0070425	negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.4	1.8	GO:2000471	regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.4	1.7	GO:0036508	protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.4	2.4	GO:0050916	sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.4	1.2	GO:2000439	positive regulation of monocyte extravasation(GO:2000439)
0.4	2.7	GO:0036438	maintenance of lens transparency(GO:0036438)
0.4	2.7	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.4	8.1	GO:0032463	negative regulation of protein homooligomerization(GO:0032463)
0.3	1.0	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
0.3	1.7	GO:0071336	regulation of hair follicle cell proliferation(GO:0071336)
0.3	3.4	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.3	4.1	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.3	4.9	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
0.3	6.4	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.3	1.2	GO:0035801	adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802)
0.3	2.3	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.3	0.8	GO:2000670	negative regulation of toll-like receptor 2 signaling pathway(GO:0034136) positive regulation of dendritic cell apoptotic process(GO:2000670)
0.3	2.4	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.3	4.6	GO:0001778	plasma membrane repair(GO:0001778)
0.3	2.3	GO:0006776	vitamin A metabolic process(GO:0006776)
0.3	6.6	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.3	3.5	GO:0039702	viral budding via host ESCRT complex(GO:0039702)
0.2	2.7	GO:0061042	vascular wound healing(GO:0061042)
0.2	1.2	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
0.2	2.4	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.2	0.9	GO:0035747	natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.2	4.3	GO:2000675	egg activation(GO:0007343) negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.2	0.7	GO:0090149	mitochondrial membrane fission(GO:0090149)
0.2	1.1	GO:0034421	post-translational protein acetylation(GO:0034421)
0.2	3.9	GO:0071257	cellular response to electrical stimulus(GO:0071257)
0.2	3.2	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.2	1.7	GO:0006450	regulation of translational fidelity(GO:0006450)
0.2	1.5	GO:0045218	zonula adherens maintenance(GO:0045218)
0.2	0.8	GO:0046381	CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.2	1.0	GO:0031022	nuclear migration along microfilament(GO:0031022)
0.2	2.9	GO:0030259	lipid glycosylation(GO:0030259)
0.2	3.4	GO:0015693	magnesium ion transport(GO:0015693)
0.2	0.7	GO:0060709	glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.2	3.0	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.2	0.5	GO:0043323	positive regulation of natural killer cell degranulation(GO:0043323)
0.2	2.3	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.2	0.8	GO:0071922	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.2	1.1	GO:1901228	positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.2	0.6	GO:0071348	cellular response to interleukin-11(GO:0071348)
0.2	1.4	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.1	0.6	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
0.1	0.7	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1	1.3	GO:0006108	malate metabolic process(GO:0006108)
0.1	3.0	GO:1903540	neurotransmitter receptor transport to plasma membrane(GO:0098877) neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540)
0.1	1.5	GO:0070574	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1	0.5	GO:0032888	regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1	4.1	GO:0071378	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1	0.4	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) establishment of viral latency(GO:0019043)
0.1	0.7	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.1	1.5	GO:0019068	virion assembly(GO:0019068)
0.1	1.2	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.1	0.7	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.1	0.6	GO:0006105	succinate metabolic process(GO:0006105)
0.1	12.0	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1	2.8	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1	1.5	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.1	3.1	GO:0001516	prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.1	1.5	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1	1.1	GO:0000022	mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.1	3.0	GO:0045116	protein neddylation(GO:0045116)
0.1	1.9	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.1	0.4	GO:1905077	negative regulation of interleukin-17 secretion(GO:1905077)
0.1	0.4	GO:0034499	late endosome to Golgi transport(GO:0034499)
0.1	1.0	GO:0021506	anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1	1.1	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.1	1.3	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.1	4.4	GO:0015893	drug transport(GO:0015893)
0.1	1.6	GO:0042473	outer ear morphogenesis(GO:0042473) regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1	3.6	GO:0031424	keratinization(GO:0031424)
0.1	1.8	GO:0051900	regulation of mitochondrial depolarization(GO:0051900)
0.1	1.2	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.1	0.4	GO:0044565	dendritic cell proliferation(GO:0044565)
0.1	4.4	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.1	1.1	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.1	1.0	GO:0031145	anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.1	3.7	GO:0006829	zinc II ion transport(GO:0006829)
0.1	0.3	GO:0070889	platelet alpha granule organization(GO:0070889)
0.1	1.1	GO:0060352	cell adhesion molecule production(GO:0060352)
0.1	0.6	GO:0070163	positive regulation of neutrophil apoptotic process(GO:0033031) adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
0.1	0.4	GO:0001830	trophectodermal cell fate commitment(GO:0001830)
0.1	0.4	GO:0034627	nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1	7.2	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.1	3.4	GO:0006506	GPI anchor biosynthetic process(GO:0006506)
0.1	1.4	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1	4.9	GO:0030968	endoplasmic reticulum unfolded protein response(GO:0030968)
0.1	1.0	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.1	1.2	GO:0060033	anatomical structure regression(GO:0060033)
0.1	3.7	GO:0031529	ruffle organization(GO:0031529)
0.1	1.8	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	0.2	GO:2000847	negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1	0.3	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.1	0.7	GO:0031937	positive regulation of chromatin silencing(GO:0031937)
0.1	0.7	GO:0060693	regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.1	0.7	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1	1.4	GO:0006691	leukotriene metabolic process(GO:0006691)
0.0	0.8	GO:0046415	urate metabolic process(GO:0046415)
0.0	1.1	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.0	3.0	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0	3.9	GO:0002181	cytoplasmic translation(GO:0002181)
0.0	0.3	GO:0015867	ATP transport(GO:0015867)
0.0	0.2	GO:0070459	prolactin secretion(GO:0070459)
0.0	1.3	GO:0043536	positive regulation of blood vessel endothelial cell migration(GO:0043536)
0.0	0.8	GO:0043306	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0	0.5	GO:0051665	membrane raft localization(GO:0051665)
0.0	1.0	GO:0006744	ubiquinone biosynthetic process(GO:0006744)
0.0	0.2	GO:0002084	protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0	1.1	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	2.2	GO:0007212	dopamine receptor signaling pathway(GO:0007212)
0.0	3.0	GO:0051881	regulation of mitochondrial membrane potential(GO:0051881)
0.0	2.2	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.0	0.2	GO:1901355	circadian regulation of translation(GO:0097167) response to rapamycin(GO:1901355)
0.0	0.5	GO:0035330	regulation of hippo signaling(GO:0035330)
0.0	0.8	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	1.2	GO:0002446	neutrophil mediated immunity(GO:0002446)
0.0	5.3	GO:0042633	molting cycle(GO:0042303) hair cycle(GO:0042633)
0.0	0.4	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.9	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0	0.0	GO:1904732	regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
0.0	0.2	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
0.0	1.7	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.9	GO:0072673	lamellipodium morphogenesis(GO:0072673)
0.0	0.6	GO:0030238	male sex determination(GO:0030238)
0.0	0.2	GO:1903551	regulation of extracellular exosome assembly(GO:1903551)
0.0	0.7	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	2.6	GO:0022900	electron transport chain(GO:0022900)
0.0	2.7	GO:0030148	sphingolipid biosynthetic process(GO:0030148)
0.0	4.7	GO:0006958	complement activation, classical pathway(GO:0006958)
0.0	0.2	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
0.0	0.3	GO:0006103	2-oxoglutarate metabolic process(GO:0006103)
0.0	9.1	GO:0016042	lipid catabolic process(GO:0016042)
0.0	0.4	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0	5.3	GO:0035304	regulation of protein dephosphorylation(GO:0035304)
0.0	1.4	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.0	0.8	GO:0043171	peptide catabolic process(GO:0043171)
0.0	0.7	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.6	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.1	GO:0032055	negative regulation of translation in response to stress(GO:0032055)
0.0	0.6	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.2	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.1	GO:1990428	miRNA transport(GO:1990428)
0.0	0.7	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.0	0.1	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0	2.2	GO:0008033	tRNA processing(GO:0008033)
0.0	0.1	GO:0097240	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0	0.9	GO:0045761	regulation of adenylate cyclase activity(GO:0045761)
0.0	0.4	GO:0010569	regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0	0.4	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.2	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
0.0	0.2	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.3	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0	0.3	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.1	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0	0.5	GO:0010501	RNA secondary structure unwinding(GO:0010501)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.8	5.4	GO:1902560	GMP reductase complex(GO:1902560)
1.3	6.6	GO:0030690	Noc1p-Noc2p complex(GO:0030690)
1.0	4.8	GO:0005914	spot adherens junction(GO:0005914)
0.7	2.8	GO:0045251	mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.6	7.7	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.6	1.8	GO:0017109	glutamate-cysteine ligase complex(GO:0017109)
0.5	2.6	GO:0044393	microspike(GO:0044393)
0.5	2.4	GO:0071817	MMXD complex(GO:0071817)
0.4	2.2	GO:0035339	SPOTS complex(GO:0035339)
0.4	3.7	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.4	1.1	GO:0005854	nascent polypeptide-associated complex(GO:0005854)
0.3	2.8	GO:0061689	tricellular tight junction(GO:0061689)
0.3	0.9	GO:0000814	ESCRT II complex(GO:0000814)
0.3	2.4	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.3	4.8	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.3	1.3	GO:0032444	activin responsive factor complex(GO:0032444)
0.3	1.8	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.2	8.0	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.2	3.0	GO:0070765	gamma-secretase complex(GO:0070765)
0.2	2.3	GO:0070552	BRISC complex(GO:0070552)
0.2	2.7	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.2	2.6	GO:0000815	ESCRT III complex(GO:0000815)
0.2	0.8	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.2	8.0	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.2	3.4	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2	5.5	GO:0031528	microvillus membrane(GO:0031528)
0.2	1.6	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.2	2.0	GO:0036449	microtubule minus-end(GO:0036449)
0.2	3.4	GO:0005640	nuclear outer membrane(GO:0005640)
0.1	0.6	GO:0045281	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1	1.0	GO:0098553	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1	3.6	GO:0032433	filopodium tip(GO:0032433)
0.1	2.7	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.1	0.5	GO:0097543	ciliary inversin compartment(GO:0097543)
0.1	0.9	GO:0097441	basilar dendrite(GO:0097441)
0.1	2.2	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.1	2.8	GO:0030008	TRAPP complex(GO:0030008)
0.1	4.3	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.1	0.9	GO:0044299	C-fiber(GO:0044299)
0.1	8.2	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.1	6.5	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1	1.0	GO:0030991	intraciliary transport particle A(GO:0030991)
0.1	1.4	GO:0000813	ESCRT I complex(GO:0000813)
0.1	1.2	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1	3.0	GO:0097546	recycling endosome membrane(GO:0055038) ciliary base(GO:0097546)
0.1	0.6	GO:0070847	core mediator complex(GO:0070847)
0.1	2.3	GO:0030056	hemidesmosome(GO:0030056)
0.1	2.2	GO:0042588	zymogen granule(GO:0042588)
0.1	1.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.1	3.3	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.1	5.2	GO:0031985	Golgi cisterna(GO:0031985)
0.1	1.9	GO:0030131	clathrin adaptor complex(GO:0030131)
0.1	1.1	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	3.6	GO:0001533	cornified envelope(GO:0001533)
0.1	3.2	GO:0005719	nuclear euchromatin(GO:0005719)
0.1	0.8	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.1	0.5	GO:0000322	storage vacuole(GO:0000322)
0.1	0.9	GO:0031209	SCAR complex(GO:0031209)
0.1	1.7	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1	0.4	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.1	3.2	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.1	3.1	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.1	7.9	GO:0005604	basement membrane(GO:0005604)
0.1	4.8	GO:0000118	histone deacetylase complex(GO:0000118)
0.1	1.6	GO:0097225	sperm midpiece(GO:0097225)
0.1	0.7	GO:0034709	methylosome(GO:0034709)
0.1	1.5	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.6	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.9	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.0	1.2	GO:0005795	Golgi stack(GO:0005795)
0.0	13.4	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	2.7	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	0.2	GO:0042583	chromaffin granule(GO:0042583)
0.0	0.3	GO:0045252	dihydrolipoyl dehydrogenase complex(GO:0045240) oxoglutarate dehydrogenase complex(GO:0045252)
0.0	3.0	GO:0034707	chloride channel complex(GO:0034707)
0.0	4.7	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.0	4.2	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	4.6	GO:0005901	caveola(GO:0005901)
0.0	2.2	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.3	GO:0071439	clathrin complex(GO:0071439)
0.0	1.0	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	1.5	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	1.5	GO:0043034	costamere(GO:0043034)
0.0	9.7	GO:0031965	nuclear membrane(GO:0031965)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.4	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.0	3.1	GO:0032587	ruffle membrane(GO:0032587)
0.0	1.6	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.2	GO:0071986	Ragulator complex(GO:0071986)
0.0	4.1	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0	0.1	GO:0043614	multi-eIF complex(GO:0043614)
0.0	0.6	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	1.1	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.9	GO:0030667	secretory granule membrane(GO:0030667)
0.0	0.2	GO:0070652	HAUS complex(GO:0070652)
0.0	1.5	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	3.3	GO:0005635	nuclear envelope(GO:0005635)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126) COPI-coated vesicle membrane(GO:0030663)
0.0	1.6	GO:0072562	blood microparticle(GO:0072562)
0.0	0.2	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.3	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.2	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	1.4	GO:0070160	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.6	7.7	GO:0035375	zymogen binding(GO:0035375)
1.8	5.4	GO:0003920	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
1.6	6.6	GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
1.0	3.1	GO:0022865	transmembrane electron transfer carrier(GO:0022865)
1.0	4.1	GO:0051435	BH4 domain binding(GO:0051435)
0.9	2.7	GO:0047256	beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.8	2.4	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.7	3.6	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.7	2.8	GO:1990932	5.8S rRNA binding(GO:1990932)
0.7	2.7	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.6	4.3	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.6	2.4	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
0.6	1.8	GO:0004357	glutamate-cysteine ligase activity(GO:0004357)
0.6	1.7	GO:0016501	prostacyclin receptor activity(GO:0016501)
0.6	2.8	GO:0004174	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.5	4.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.5	2.5	GO:0097003	adipokinetic hormone receptor activity(GO:0097003)
0.5	1.4	GO:0005110	frizzled-2 binding(GO:0005110)
0.5	1.8	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.4	4.5	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.4	1.6	GO:0043532	angiostatin binding(GO:0043532)
0.4	2.3	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
0.4	7.6	GO:0035497	cAMP response element binding(GO:0035497)
0.4	1.1	GO:0015140	malate transmembrane transporter activity(GO:0015140)
0.3	3.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.3	1.7	GO:0051185	coenzyme transporter activity(GO:0051185)
0.3	5.0	GO:0042577	lipid phosphatase activity(GO:0042577)
0.3	1.6	GO:0008240	tripeptidyl-peptidase activity(GO:0008240) bradykinin receptor binding(GO:0031711)
0.3	4.0	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.3	1.9	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.3	0.9	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.3	4.8	GO:0045294	alpha-catenin binding(GO:0045294)
0.3	1.5	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.3	3.2	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.3	1.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.3	2.2	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.3	3.9	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.3	0.8	GO:0030348	syntaxin-3 binding(GO:0030348)
0.3	2.7	GO:0004579	oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.3	2.4	GO:0015217	ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.3	1.3	GO:0030060	L-malate dehydrogenase activity(GO:0030060)
0.2	13.7	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.2	0.9	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.2	0.8	GO:0005128	erythropoietin receptor binding(GO:0005128)
0.2	2.7	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2	3.4	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.2	0.6	GO:0051538	succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.2	2.8	GO:0030274	LIM domain binding(GO:0030274)
0.2	7.2	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.2	0.7	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.2	1.3	GO:0043199	sulfate binding(GO:0043199)
0.2	1.7	GO:0004064	arylesterase activity(GO:0004064)
0.2	2.3	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.2	2.2	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.2	0.5	GO:0031755	endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.1	0.9	GO:0070004	cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.1	0.6	GO:0045131	pre-mRNA branch point binding(GO:0045131)
0.1	4.4	GO:0015238	drug transmembrane transporter activity(GO:0015238)
0.1	1.7	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1	12.0	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1	2.9	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1	2.3	GO:0003993	acid phosphatase activity(GO:0003993)
0.1	5.9	GO:0051059	NF-kappaB binding(GO:0051059)
0.1	1.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.1	0.9	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.1	2.8	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.1	1.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.1	2.2	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.1	1.4	GO:0046790	virion binding(GO:0046790)
0.1	3.0	GO:0031489	myosin V binding(GO:0031489)
0.1	1.0	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1	1.0	GO:0045504	dynein heavy chain binding(GO:0045504)
0.1	0.7	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1	0.6	GO:0004673	protein histidine kinase activity(GO:0004673)
0.1	1.8	GO:0042288	MHC class I protein binding(GO:0042288)
0.1	0.3	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1	2.4	GO:0008327	methyl-CpG binding(GO:0008327)
0.1	0.3	GO:0016748	succinyltransferase activity(GO:0016748)
0.1	0.8	GO:0034511	U3 snoRNA binding(GO:0034511)
0.1	2.7	GO:0008143	poly(A) binding(GO:0008143)
0.1	7.8	GO:0004620	phospholipase activity(GO:0004620)
0.1	0.7	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.1	1.2	GO:0050693	LBD domain binding(GO:0050693)
0.1	0.4	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1	2.0	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.1	0.2	GO:0001160	transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1	1.5	GO:0008179	adenylate cyclase binding(GO:0008179)
0.1	0.6	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1	1.8	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.1	1.9	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1	0.4	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.1	0.8	GO:1901702	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1	1.1	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1	1.6	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1	0.4	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1	1.4	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.4	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.0	0.9	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	9.0	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	1.4	GO:0070064	proline-rich region binding(GO:0070064)
0.0	1.2	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.0	0.6	GO:0042731	PH domain binding(GO:0042731)
0.0	0.9	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.6	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	1.5	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	1.7	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.8	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0	1.5	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	4.7	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	2.6	GO:0015485	cholesterol binding(GO:0015485)
0.0	1.2	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.6	GO:0019841	retinol binding(GO:0019841)
0.0	0.8	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	1.5	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.2	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	1.0	GO:0071949	FAD binding(GO:0071949)
0.0	0.7	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	3.4	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	15.4	GO:0005198	structural molecule activity(GO:0005198)
0.0	0.2	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.6	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	2.7	GO:0005254	chloride channel activity(GO:0005254)
0.0	2.0	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	0.5	GO:0016502	purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.0	1.1	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.0	3.4	GO:0051015	actin filament binding(GO:0051015)
0.0	1.0	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.2	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	2.4	GO:0008237	metallopeptidase activity(GO:0008237)
0.0	0.1	GO:0089720	caspase binding(GO:0089720)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	6.6	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2	2.6	PID S1P S1P4 PATHWAY	S1P4 pathway
0.1	3.0	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.1	3.0	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.1	4.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	10.5	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.1	4.1	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.1	1.3	PID ALK2 PATHWAY	ALK2 signaling events
0.1	1.6	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	5.7	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.1	1.6	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	4.8	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.9	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	1.9	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	2.1	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	1.4	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	1.7	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.6	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	1.4	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	7.9	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	2.9	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.0	0.3	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	1.3	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	0.6	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	1.2	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	1.1	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	1.4	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.9	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.4	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	1.2	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	1.2	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.6	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.0	1.1	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	1.8	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.5	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	3.0	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.7	PID CDC42 PATHWAY	CDC42 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	6.7	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.3	4.4	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.2	3.2	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.2	2.4	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.2	3.4	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.2	3.9	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.2	8.0	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.2	4.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.2	3.1	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.2	3.7	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.2	3.0	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.2	2.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1	4.5	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.1	4.1	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	3.3	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	1.6	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	1.7	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	3.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.1	4.4	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.1	2.6	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1	4.4	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1	1.7	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.1	9.3	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.1	1.6	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.1	1.9	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1	0.7	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.1	1.5	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	1.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.1	0.8	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	1.8	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	1.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.0	1.3	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	2.4	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.8	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.7	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	3.2	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	3.7	REACTOME ASPARAGINE N LINKED GLYCOSYLATION	Genes involved in Asparagine N-linked glycosylation
0.0	0.5	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	2.7	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	1.5	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.7	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	1.1	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	1.4	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	2.2	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.4	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.9	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.2	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	1.9	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.5	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.6	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.6	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	1.0	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.9	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.6	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	1.7	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.3	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.6	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0	0.5	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.8	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.4	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling