PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
Spib Links Ensembl NCBI MGI UniProt	ENSMUSG00000008193.14	Spib

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Spib	mm39_v1_chr7_-_44181477_44181502	0.94	2.9e-33	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr6_-_136918671 Show fit	50.39	ENSMUST00000032344.12	Arhgdib Links Ensembl NCBI MGI UniProt Show fit	Rho, GDP dissociation inhibitor (GDI) beta
chr15_-_66684442 Show fit	36.13	ENSMUST00000100572.10	Sla Links Ensembl NCBI MGI UniProt Show fit	src-like adaptor
chr11_+_11635908 Show fit	34.59	ENSMUST00000065433.12	Ikzf1 Links Ensembl NCBI MGI UniProt Show fit	IKAROS family zinc finger 1
chr19_+_4204605 Show fit	32.32	ENSMUST00000061086.9	Ptprcap Links Ensembl NCBI MGI UniProt Show fit	protein tyrosine phosphatase, receptor type, C polypeptide-associated protein
chr1_-_170755136 Show fit	31.75	ENSMUST00000046322.14 ENSMUST00000159171.2	Fcrla Links Ensembl NCBI MGI UniProt Show fit	Fc receptor-like A
chr11_-_34674677 Show fit	31.26	ENSMUST00000093193.12 ENSMUST00000101365.9	Dock2 Links Ensembl NCBI MGI UniProt Show fit	dedicator of cyto-kinesis 2
chr7_-_44888220 Show fit	30.58	ENSMUST00000210372.2 ENSMUST00000209779.2 ENSMUST00000098461.10 ENSMUST00000211373.2	Cd37 Links Ensembl NCBI MGI UniProt Show fit	CD37 antigen
chr10_+_130158737 Show fit	30.41	ENSMUST00000217702.2 ENSMUST00000042586.10 ENSMUST00000218605.2	Tespa1 Links Ensembl NCBI MGI UniProt Show fit	thymocyte expressed, positive selection associated 1
chr4_+_130640436 Show fit	29.63	ENSMUST00000151698.8	Laptm5 Links Ensembl NCBI MGI UniProt Show fit	lysosomal-associated protein transmembrane 5
chrX_+_106132840 Show fit	29.57	ENSMUST00000118666.8 ENSMUST00000053375.4	P2ry10 Links Ensembl NCBI MGI UniProt Show fit	purinergic receptor P2Y, G-protein coupled 10
chr11_-_16958647 Show fit	27.82	ENSMUST00000102881.10	Plek Links Ensembl NCBI MGI UniProt Show fit	pleckstrin
chr9_+_55997246 Show fit	27.78	ENSMUST00000059206.8	Pstpip1 Links Ensembl NCBI MGI UniProt Show fit	proline-serine-threonine phosphatase-interacting protein 1
chr6_+_129326927 Show fit	27.73	ENSMUST00000065289.6	Clec12a Links Ensembl NCBI MGI UniProt Show fit	C-type lectin domain family 12, member a
chr17_+_57586094 Show fit	26.42	ENSMUST00000169220.9 ENSMUST00000005889.16 ENSMUST00000112870.5	Vav1 Links Ensembl NCBI MGI UniProt Show fit	vav 1 oncogene
chr7_-_126303351 Show fit	26.29	ENSMUST00000106364.8	Coro1a Links Ensembl NCBI MGI UniProt Show fit	coronin, actin binding protein 1A
chr6_-_136918495 Show fit	26.13	ENSMUST00000111892.8	Arhgdib Links Ensembl NCBI MGI UniProt Show fit	Rho, GDP dissociation inhibitor (GDI) beta
chr6_+_41095752 Show fit	25.63	ENSMUST00000103269.3	Trbv12-2 Links Ensembl NCBI MGI UniProt Show fit	T cell receptor beta, variable 12-2
chr1_+_171509565 Show fit	25.42	ENSMUST00000015499.14 ENSMUST00000068584.7	Cd48 Links Ensembl NCBI MGI UniProt Show fit	CD48 antigen
chr4_-_43454561 Show fit	25.34	ENSMUST00000107926.8 ENSMUST00000107925.8	Cd72 Links Ensembl NCBI MGI UniProt Show fit	CD72 antigen
chr15_-_78456898 Show fit	25.16	ENSMUST00000043214.8	Rac2 Links Ensembl NCBI MGI UniProt Show fit	Rac family small GTPase 2
chr6_+_122929591 Show fit	24.72	ENSMUST00000088468.7	Clec4a3 Links Ensembl NCBI MGI UniProt Show fit	C-type lectin domain family 4, member a3
chr7_+_43057611 Show fit	24.59	ENSMUST00000005592.7	Siglecg Links Ensembl NCBI MGI UniProt Show fit	sialic acid binding Ig-like lectin G
chr15_+_78210190 Show fit	24.41	ENSMUST00000229034.2 ENSMUST00000096355.4	Csf2rb Links Ensembl NCBI MGI UniProt Show fit	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr1_+_171594690 Show fit	24.35	ENSMUST00000015460.5	Slamf1 Links Ensembl NCBI MGI UniProt Show fit	signaling lymphocytic activation molecule family member 1
chr7_-_126303887 Show fit	24.25	ENSMUST00000131415.8	Coro1a Links Ensembl NCBI MGI UniProt Show fit	coronin, actin binding protein 1A
chr4_+_130640611 Show fit	23.54	ENSMUST00000156225.8 ENSMUST00000156742.8	Laptm5 Links Ensembl NCBI MGI UniProt Show fit	lysosomal-associated protein transmembrane 5
chr15_+_78209920 Show fit	23.20	ENSMUST00000230264.3	Csf2rb Links Ensembl NCBI MGI UniProt Show fit	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr1_-_170755109 Show fit	22.97	ENSMUST00000162136.2 ENSMUST00000162887.2	Fcrla Links Ensembl NCBI MGI UniProt Show fit	Fc receptor-like A
chr14_+_75368939 Show fit	22.79	ENSMUST00000125833.8 ENSMUST00000124499.8	Lcp1 Links Ensembl NCBI MGI UniProt Show fit	lymphocyte cytosolic protein 1
chr13_+_30933209 Show fit	22.42	ENSMUST00000021784.10 ENSMUST00000110307.3 ENSMUST00000222125.2	Irf4 Links Ensembl NCBI MGI UniProt Show fit	interferon regulatory factor 4
chr11_+_68322945 Show fit	22.20	ENSMUST00000021283.8	Pik3r5 Links Ensembl NCBI MGI UniProt Show fit	phosphoinositide-3-kinase regulatory subunit 5
chr16_-_36486429 Show fit	21.89	ENSMUST00000089620.11	Cd86 Links Ensembl NCBI MGI UniProt Show fit	CD86 antigen
chr11_+_61544085 Show fit	21.77	ENSMUST00000004959.3	Grap Links Ensembl NCBI MGI UniProt Show fit	GRB2-related adaptor protein
chr15_+_103362195 Show fit	21.39	ENSMUST00000047405.9	Nckap1l Links Ensembl NCBI MGI UniProt Show fit	NCK associated protein 1 like
chr2_+_43638814 Show fit	21.26	ENSMUST00000112824.8 ENSMUST00000055776.8	Arhgap15 Links Ensembl NCBI MGI UniProt Show fit	Rho GTPase activating protein 15
chr5_-_134258435 Show fit	21.22	ENSMUST00000016094.13 ENSMUST00000111275.8 ENSMUST00000144086.2	Ncf1 Links Ensembl NCBI MGI UniProt Show fit	neutrophil cytosolic factor 1
chr7_-_44888532 Show fit	21.22	ENSMUST00000033063.15	Cd37 Links Ensembl NCBI MGI UniProt Show fit	CD37 antigen
chr6_+_38895902 Show fit	21.17	ENSMUST00000003017.13	Tbxas1 Links Ensembl NCBI MGI UniProt Show fit	thromboxane A synthase 1, platelet
chr8_+_72943455 Show fit	21.13	ENSMUST00000072097.14	Hsh2d Links Ensembl NCBI MGI UniProt Show fit	hematopoietic SH2 domain containing
chr16_+_36755338 Show fit	20.95	ENSMUST00000023531.15	Hcls1 Links Ensembl NCBI MGI UniProt Show fit	hematopoietic cell specific Lyn substrate 1
chr7_-_3723381 Show fit	20.42	ENSMUST00000078451.7	Pirb Links Ensembl NCBI MGI UniProt Show fit	paired Ig-like receptor B
chr15_-_82917495 Show fit	20.37	ENSMUST00000231165.2	Nfam1 Links Ensembl NCBI MGI UniProt Show fit	Nfat activating molecule with ITAM motif 1
chr5_+_86219593 Show fit	20.34	ENSMUST00000198435.5 ENSMUST00000031171.9	Stap1 Links Ensembl NCBI MGI UniProt Show fit	signal transducing adaptor family member 1
chr11_-_115024807 Show fit	20.31	ENSMUST00000106561.8 ENSMUST00000051264.14 ENSMUST00000106562.3	Cd300lf Links Ensembl NCBI MGI UniProt Show fit	CD300 molecule like family member F
chr5_+_149201577 Show fit	20.30	ENSMUST00000071130.5	Alox5ap Links Ensembl NCBI MGI UniProt Show fit	arachidonate 5-lipoxygenase activating protein
chr19_+_6449887 Show fit	20.26	ENSMUST00000146601.8 ENSMUST00000150713.8	Rasgrp2 Links Ensembl NCBI MGI UniProt Show fit	RAS, guanyl releasing protein 2
chr7_-_126303689 Show fit	20.21	ENSMUST00000135087.8	Coro1a Links Ensembl NCBI MGI UniProt Show fit	coronin, actin binding protein 1A
chr7_-_3848050 Show fit	20.15	ENSMUST00000108615.10 ENSMUST00000119469.2	Pira2 Links Ensembl NCBI MGI UniProt Show fit	paired-Ig-like receptor A2
chr9_+_123822000 Show fit	20.06	ENSMUST00000039171.9	Ccr3 Links Ensembl NCBI MGI UniProt Show fit	chemokine (C-C motif) receptor 3
chr2_+_24276616 Show fit	19.74	ENSMUST00000166388.2	Psd4 Links Ensembl NCBI MGI UniProt Show fit	pleckstrin and Sec7 domain containing 4
chr2_-_181333597 Show fit	19.60	ENSMUST00000108778.8 ENSMUST00000165416.8	Rgs19 Links Ensembl NCBI MGI UniProt Show fit	regulator of G-protein signaling 19
chr2_+_22664094 Show fit	19.43	ENSMUST00000014290.15	Apbb1ip Links Ensembl NCBI MGI UniProt Show fit	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr7_-_44888465 Show fit	19.38	ENSMUST00000210078.2	Cd37 Links Ensembl NCBI MGI UniProt Show fit	CD37 antigen
chr3_-_105839980 Show fit	19.37	ENSMUST00000098758.5	I830077J02Rik Links Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA I830077J02 gene
chr6_-_124710084 Show fit	18.54	ENSMUST00000112484.10	Ptpn6 Links Ensembl NCBI MGI UniProt Show fit	protein tyrosine phosphatase, non-receptor type 6
chr11_-_103235475 Show fit	18.49	ENSMUST00000041385.14	Arhgap27 Links Ensembl NCBI MGI UniProt Show fit	Rho GTPase activating protein 27
chr15_+_78210242 Show fit	18.47	ENSMUST00000229678.2 ENSMUST00000231888.2	Csf2rb Links Ensembl NCBI MGI UniProt Show fit	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr13_+_102830029 Show fit	18.42	ENSMUST00000022124.10 ENSMUST00000171267.2 ENSMUST00000167144.2 ENSMUST00000170878.2	Cd180 Links Ensembl NCBI MGI UniProt Show fit	CD180 antigen
chr3_-_59118293 Show fit	18.17	ENSMUST00000040622.3	P2ry13 Links Ensembl NCBI MGI UniProt Show fit	purinergic receptor P2Y, G-protein coupled 13
chr5_+_149202157 Show fit	17.60	ENSMUST00000200806.4	Alox5ap Links Ensembl NCBI MGI UniProt Show fit	arachidonate 5-lipoxygenase activating protein
chr6_+_122929627 Show fit	17.46	ENSMUST00000204427.2	Clec4a3 Links Ensembl NCBI MGI UniProt Show fit	C-type lectin domain family 4, member a3
chr12_+_98234884 Show fit	17.42	ENSMUST00000075072.6	Gpr65 Links Ensembl NCBI MGI UniProt Show fit	G-protein coupled receptor 65
chr15_-_9529898 Show fit	17.40	ENSMUST00000228782.2 ENSMUST00000003981.6	Il7r Links Ensembl NCBI MGI UniProt Show fit	interleukin 7 receptor
chr7_-_45570828 Show fit	17.38	ENSMUST00000038876.13	Emp3 Links Ensembl NCBI MGI UniProt Show fit	epithelial membrane protein 3
chr19_+_6449776 Show fit	17.35	ENSMUST00000113468.8	Rasgrp2 Links Ensembl NCBI MGI UniProt Show fit	RAS, guanyl releasing protein 2
chr7_-_45570538 Show fit	17.34	ENSMUST00000210297.2	Emp3 Links Ensembl NCBI MGI UniProt Show fit	epithelial membrane protein 3
chr1_-_171061902 Show fit	17.22	ENSMUST00000079957.12	Fcer1g Links Ensembl NCBI MGI UniProt Show fit	Fc receptor, IgE, high affinity I, gamma polypeptide
chr2_-_181335697 Show fit	17.09	ENSMUST00000108779.8 ENSMUST00000108769.8 ENSMUST00000108772.8	Rgs19 Links Ensembl NCBI MGI UniProt Show fit	regulator of G-protein signaling 19
chr13_-_113237505 Show fit	16.76	ENSMUST00000224282.2 ENSMUST00000023897.7	Gzma Links Ensembl NCBI MGI UniProt Show fit	granzyme A
chr19_+_24976864 Show fit	16.73	ENSMUST00000025831.8	Dock8 Links Ensembl NCBI MGI UniProt Show fit	dedicator of cytokinesis 8
chr7_-_45570674 Show fit	16.32	ENSMUST00000210939.2	Emp3 Links Ensembl NCBI MGI UniProt Show fit	epithelial membrane protein 3
chr11_-_70703365 Show fit	16.26	ENSMUST00000074572.7 ENSMUST00000108534.9	Scimp Links Ensembl NCBI MGI UniProt Show fit	SLP adaptor and CSK interacting membrane protein
chr9_+_21437440 Show fit	16.20	ENSMUST00000086361.12 ENSMUST00000173769.3	AB124611 Links Ensembl NCBI MGI UniProt Show fit	cDNA sequence AB124611
chr9_+_44990447 Show fit	15.93	ENSMUST00000050020.8	Jaml Links Ensembl NCBI MGI UniProt Show fit	junction adhesion molecule like
chr9_-_114610879 Show fit	15.81	ENSMUST00000084867.9 ENSMUST00000216760.2 ENSMUST00000035009.16	Cmtm7 Links Ensembl NCBI MGI UniProt Show fit	CKLF-like MARVEL transmembrane domain containing 7
chr6_-_106725929 Show fit	15.80	ENSMUST00000204659.3	Il5ra Links Ensembl NCBI MGI UniProt Show fit	interleukin 5 receptor, alpha
chr2_-_181335767 Show fit	15.70	ENSMUST00000002532.9	Rgs19 Links Ensembl NCBI MGI UniProt Show fit	regulator of G-protein signaling 19
chr6_-_124710030 Show fit	15.61	ENSMUST00000173647.2	Ptpn6 Links Ensembl NCBI MGI UniProt Show fit	protein tyrosine phosphatase, non-receptor type 6
chr2_+_32611067 Show fit	15.57	ENSMUST00000074248.11	Sh2d3c Links Ensembl NCBI MGI UniProt Show fit	SH2 domain containing 3C
chr17_+_35268942 Show fit	15.18	ENSMUST00000007257.10	Clic1 Links Ensembl NCBI MGI UniProt Show fit	chloride intracellular channel 1
chr2_+_90927053 Show fit	15.06	ENSMUST00000132741.3	Spi1 Links Ensembl NCBI MGI UniProt Show fit	spleen focus forming virus (SFFV) proviral integration oncogene
chr8_-_89362745 Show fit	14.85	ENSMUST00000034087.9	Snx20 Links Ensembl NCBI MGI UniProt Show fit	sorting nexin 20
chr4_-_43454600 Show fit	14.72	ENSMUST00000098105.4 ENSMUST00000098104.10 ENSMUST00000030179.11	Cd72 Links Ensembl NCBI MGI UniProt Show fit	CD72 antigen
chr10_+_96453408 Show fit	14.72	ENSMUST00000218953.2	Btg1 Links Ensembl NCBI MGI UniProt Show fit	BTG anti-proliferation factor 1
chr7_+_28834276 Show fit	14.67	ENSMUST00000161522.8 ENSMUST00000204845.3 ENSMUST00000205027.3 ENSMUST00000204194.3 ENSMUST00000203070.3 ENSMUST00000203380.3	Rasgrp4 Links Ensembl NCBI MGI UniProt Show fit	RAS guanyl releasing protein 4
chr11_+_44290884 Show fit	14.60	ENSMUST00000170513.3 ENSMUST00000102796.10	Il12b Links Ensembl NCBI MGI UniProt Show fit	interleukin 12b
chr8_+_95472218 Show fit	14.29	ENSMUST00000034231.4	Ccl22 Links Ensembl NCBI MGI UniProt Show fit	chemokine (C-C motif) ligand 22
chr2_-_181335518 Show fit	14.12	ENSMUST00000108776.8 ENSMUST00000108771.2	Rgs19 Links Ensembl NCBI MGI UniProt Show fit	regulator of G-protein signaling 19
chr15_-_78189917 Show fit	13.98	ENSMUST00000096356.5	Csf2rb2 Links Ensembl NCBI MGI UniProt Show fit	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)
chr6_-_106725895 Show fit	13.91	ENSMUST00000205004.2	Il5ra Links Ensembl NCBI MGI UniProt Show fit	interleukin 5 receptor, alpha
chr11_+_46701619 Show fit	13.78	ENSMUST00000068877.7	Timd4 Links Ensembl NCBI MGI UniProt Show fit	T cell immunoglobulin and mucin domain containing 4
chr17_-_84154173 Show fit	13.77	ENSMUST00000000687.9	Haao Links Ensembl NCBI MGI UniProt Show fit	3-hydroxyanthranilate 3,4-dioxygenase
chr1_-_38704028 Show fit	13.70	ENSMUST00000039827.14	Aff3 Links Ensembl NCBI MGI UniProt Show fit	AF4/FMR2 family, member 3
chr10_-_6930376 Show fit	13.57	ENSMUST00000105617.8	Ipcef1 Links Ensembl NCBI MGI UniProt Show fit	interaction protein for cytohesin exchange factors 1
chr7_-_3918484 Show fit	13.46	ENSMUST00000038176.15 ENSMUST00000206077.2 ENSMUST00000090689.5	Lilra6 Links Ensembl NCBI MGI UniProt Show fit	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
chr4_+_140428777 Show fit	13.20	ENSMUST00000138808.8 ENSMUST00000038893.6	Rcc2 Links Ensembl NCBI MGI UniProt Show fit	regulator of chromosome condensation 2
chr1_-_170886924 Show fit	13.15	ENSMUST00000164044.8 ENSMUST00000169017.8	Fcgr3 Links Ensembl NCBI MGI UniProt Show fit	Fc receptor, IgG, low affinity III
chr19_-_41373526 Show fit	12.97	ENSMUST00000059672.9	Pik3ap1 Links Ensembl NCBI MGI UniProt Show fit	phosphoinositide-3-kinase adaptor protein 1
chr10_+_51356728 Show fit	12.48	ENSMUST00000102894.6 ENSMUST00000219661.2 ENSMUST00000219696.2 ENSMUST00000217706.2	Lilr4b Links Ensembl NCBI MGI UniProt Show fit Gm49339 Links Ensembl NCBI MGI UniProt Show fit	leukocyte immunoglobulin-like receptor, subfamily B, member 4B predicted gene, 49339
chr11_-_114952984 Show fit	12.21	ENSMUST00000062787.8	Cd300e Links Ensembl NCBI MGI UniProt Show fit	CD300E molecule
chr17_-_34218301 Show fit	12.03	ENSMUST00000235463.2	H2-K1 Links Ensembl NCBI MGI UniProt Show fit	histocompatibility 2, K1, K region
chr15_-_36609208 Show fit	11.93	ENSMUST00000001809.15	Pabpc1 Links Ensembl NCBI MGI UniProt Show fit	poly(A) binding protein, cytoplasmic 1
chr2_+_24276545 Show fit	11.87	ENSMUST00000127242.2	Psd4 Links Ensembl NCBI MGI UniProt Show fit	pleckstrin and Sec7 domain containing 4
chr9_+_44990502 Show fit	11.80	ENSMUST00000216426.2	Jaml Links Ensembl NCBI MGI UniProt Show fit	junction adhesion molecule like
chr17_+_36179273 Show fit	11.79	ENSMUST00000190496.2	Ppp1r18 Links Ensembl NCBI MGI UniProt Show fit	protein phosphatase 1, regulatory subunit 18
chr11_+_46345784 Show fit	11.64	ENSMUST00000109229.2	Havcr2 Links Ensembl NCBI MGI UniProt Show fit	hepatitis A virus cellular receptor 2
chr15_+_6552270 Show fit	11.53	ENSMUST00000226412.2	Fyb Links Ensembl NCBI MGI UniProt Show fit	FYN binding protein
chr19_-_11313471 Show fit	11.49	ENSMUST00000056035.9 ENSMUST00000067532.11	Ms4a7 Links Ensembl NCBI MGI UniProt Show fit	membrane-spanning 4-domains, subfamily A, member 7
chr17_-_84154196 Show fit	11.42	ENSMUST00000234214.2	Haao Links Ensembl NCBI MGI UniProt Show fit	3-hydroxyanthranilate 3,4-dioxygenase
chr19_+_12438125 Show fit	11.42	ENSMUST00000081035.9	Mpeg1 Links Ensembl NCBI MGI UniProt Show fit	macrophage expressed gene 1
chr19_+_6107957 Show fit	11.39	ENSMUST00000237859.2 ENSMUST00000043074.14 ENSMUST00000236336.2 ENSMUST00000179142.2 ENSMUST00000236217.2	Fau Links Ensembl NCBI MGI UniProt Show fit	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)
chr8_+_95650315 Show fit	11.39	ENSMUST00000153448.9 ENSMUST00000166802.9 ENSMUST00000074570.10	Adgrg5 Links Ensembl NCBI MGI UniProt Show fit	adhesion G protein-coupled receptor G5
chr12_-_32258604 Show fit	11.25	ENSMUST00000053215.14	Pik3cg Links Ensembl NCBI MGI UniProt Show fit	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr12_-_32258331 Show fit	11.13	ENSMUST00000220366.2	Pik3cg Links Ensembl NCBI MGI UniProt Show fit	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr15_-_63932176 Show fit	10.93	ENSMUST00000226675.2 ENSMUST00000228226.2 ENSMUST00000227024.2	Cyrib Links Ensembl NCBI MGI UniProt Show fit	CYFIP related Rac1 interactor B
chr2_+_24235300 Show fit	10.91	ENSMUST00000114485.9 ENSMUST00000114482.3	Il1rn Links Ensembl NCBI MGI UniProt Show fit	interleukin 1 receptor antagonist
chr19_+_6108240 Show fit	10.91	ENSMUST00000237840.2	Fau Links Ensembl NCBI MGI UniProt Show fit	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)
chr6_+_83303052 Show fit	10.74	ENSMUST00000038658.15	Mob1a Links Ensembl NCBI MGI UniProt Show fit	MOB kinase activator 1A
chr11_+_46345747 Show fit	10.74	ENSMUST00000020668.15	Havcr2 Links Ensembl NCBI MGI UniProt Show fit	hepatitis A virus cellular receptor 2
chr13_+_104365432 Show fit	10.69	ENSMUST00000070761.10 ENSMUST00000225557.2	Cenpk Links Ensembl NCBI MGI UniProt Show fit	centromere protein K
chr17_+_8144822 Show fit	10.54	ENSMUST00000036370.8	Tagap Links Ensembl NCBI MGI UniProt Show fit	T cell activation Rho GTPase activating protein
chr12_-_32258469 Show fit	10.44	ENSMUST00000085469.6	Pik3cg Links Ensembl NCBI MGI UniProt Show fit	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chrX_+_72760183 Show fit	10.33	ENSMUST00000002084.14	Abcd1 Links Ensembl NCBI MGI UniProt Show fit	ATP-binding cassette, sub-family D (ALD), member 1
chr19_+_6107874 Show fit	10.28	ENSMUST00000178310.9	Fau Links Ensembl NCBI MGI UniProt Show fit	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)
chr7_+_127078371 Show fit	10.17	ENSMUST00000205432.3	Fbrs Links Ensembl NCBI MGI UniProt Show fit	fibrosin
chr9_+_123902143 Show fit	10.10	ENSMUST00000168841.3 ENSMUST00000055918.7	Ccr2 Links Ensembl NCBI MGI UniProt Show fit	chemokine (C-C motif) receptor 2
chr6_+_83302998 Show fit	10.04	ENSMUST00000055261.11	Mob1a Links Ensembl NCBI MGI UniProt Show fit	MOB kinase activator 1A
chr19_+_6391148 Show fit	10.00	ENSMUST00000025897.13 ENSMUST00000130382.8	Map4k2 Links Ensembl NCBI MGI UniProt Show fit	mitogen-activated protein kinase kinase kinase kinase 2
chr6_+_29529275 Show fit	9.97	ENSMUST00000163511.7	Irf5 Links Ensembl NCBI MGI UniProt Show fit	interferon regulatory factor 5
chr8_-_25592385 Show fit	9.93	ENSMUST00000064883.14	Plekha2 Links Ensembl NCBI MGI UniProt Show fit	pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr1_+_87548026 Show fit	9.87	ENSMUST00000169754.8 ENSMUST00000042275.15 ENSMUST00000168783.8	Inpp5d Links Ensembl NCBI MGI UniProt Show fit	inositol polyphosphate-5-phosphatase D
chr9_+_94551929 Show fit	9.78	ENSMUST00000033463.10	Slc9a9 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr14_+_53791444 Show fit	9.78	ENSMUST00000198297.2	Trav14-1 Links Ensembl NCBI MGI UniProt Show fit	T cell receptor alpha variable 14-1
chr3_-_100936859 Show fit	9.69	ENSMUST00000147399.9	Cd101 Links Ensembl NCBI MGI UniProt Show fit	CD101 antigen
chr11_-_79418500 Show fit	9.51	ENSMUST00000154415.2	Evi2a Links Ensembl NCBI MGI UniProt Show fit	ecotropic viral integration site 2a
chr4_+_109200225 Show fit	9.43	ENSMUST00000030281.12	Eps15 Links Ensembl NCBI MGI UniProt Show fit	epidermal growth factor receptor pathway substrate 15
chr15_-_78189822 Show fit	9.40	ENSMUST00000230115.3	Csf2rb2 Links Ensembl NCBI MGI UniProt Show fit	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)
chr19_+_6135013 Show fit	9.38	ENSMUST00000025704.3	Cdca5 Links Ensembl NCBI MGI UniProt Show fit	cell division cycle associated 5
chr12_+_105996961 Show fit	9.37	ENSMUST00000220629.2	Vrk1 Links Ensembl NCBI MGI UniProt Show fit	vaccinia related kinase 1
chr4_-_123644091 Show fit	9.14	ENSMUST00000102636.4	Akirin1 Links Ensembl NCBI MGI UniProt Show fit	akirin 1
chr4_-_115980813 Show fit	9.08	ENSMUST00000102704.4 ENSMUST00000102705.10	Rad54l Links Ensembl NCBI MGI UniProt Show fit	RAD54 like (S. cerevisiae)
chrX_+_141464722 Show fit	8.86	ENSMUST00000112896.9	Tmem164 Links Ensembl NCBI MGI UniProt Show fit	transmembrane protein 164
chr17_-_50497682 Show fit	8.82	ENSMUST00000044503.14	Rftn1 Links Ensembl NCBI MGI UniProt Show fit	raftlin lipid raft linker 1
chr2_-_38895586 Show fit	8.74	ENSMUST00000080861.6	Rpl35 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein L35
chr12_-_28685849 Show fit	8.71	ENSMUST00000221871.2	Rps7 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein S7
chr2_+_25313240 Show fit	8.67	ENSMUST00000134259.8 ENSMUST00000100320.5	Fut7 Links Ensembl NCBI MGI UniProt Show fit	fucosyltransferase 7
chr10_-_81360059 Show fit	8.66	ENSMUST00000043709.8	Gna15 Links Ensembl NCBI MGI UniProt Show fit	guanine nucleotide binding protein, alpha 15
chr14_-_66071412 Show fit	8.57	ENSMUST00000022613.10	Esco2 Links Ensembl NCBI MGI UniProt Show fit	establishment of sister chromatid cohesion N-acetyltransferase 2
chr9_-_114811807 Show fit	8.50	ENSMUST00000053150.8	Rps27rt Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein S27, retrogene
chr17_-_35391583 Show fit	8.50	ENSMUST00000173106.2	Aif1 Links Ensembl NCBI MGI UniProt Show fit	allograft inflammatory factor 1
chr4_+_135870808 Show fit	8.49	ENSMUST00000008016.3	Id3 Links Ensembl NCBI MGI UniProt Show fit	inhibitor of DNA binding 3
chr3_-_135313982 Show fit	8.44	ENSMUST00000132668.8	Nfkb1 Links Ensembl NCBI MGI UniProt Show fit	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
chr4_-_118266416 Show fit	8.42	ENSMUST00000075406.12	Szt2 Links Ensembl NCBI MGI UniProt Show fit	SZT2 subunit of KICSTOR complex
chr11_-_115590318 Show fit	8.40	ENSMUST00000106497.8	Grb2 Links Ensembl NCBI MGI UniProt Show fit	growth factor receptor bound protein 2
chr15_+_97259060 Show fit	8.07	ENSMUST00000228521.2 ENSMUST00000226495.2	Pced1b Links Ensembl NCBI MGI UniProt Show fit	PC-esterase domain containing 1B
chr4_-_136613498 Show fit	8.02	ENSMUST00000046384.9	C1qb Links Ensembl NCBI MGI UniProt Show fit	complement component 1, q subcomponent, beta polypeptide
chr9_+_106080307 Show fit	8.01	ENSMUST00000024047.12 ENSMUST00000216348.2	Twf2 Links Ensembl NCBI MGI UniProt Show fit	twinfilin actin binding protein 2
chr13_+_20978283 Show fit	8.01	ENSMUST00000021757.5 ENSMUST00000221982.2	Aoah Links Ensembl NCBI MGI UniProt Show fit	acyloxyacyl hydrolase
chr11_-_115590133 Show fit	7.99	ENSMUST00000106499.8	Grb2 Links Ensembl NCBI MGI UniProt Show fit	growth factor receptor bound protein 2
chr11_+_87628356 Show fit	7.94	ENSMUST00000093955.12	Supt4a Links Ensembl NCBI MGI UniProt Show fit	SPT4A, DSIF elongation factor subunit
chr2_+_112096154 Show fit	7.86	ENSMUST00000110991.9	Slc12a6 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 12, member 6
chr17_-_35827676 Show fit	7.83	ENSMUST00000160885.2 ENSMUST00000159009.2 ENSMUST00000161012.8	Tcf19 Links Ensembl NCBI MGI UniProt Show fit	transcription factor 19
chrX_+_108240356 Show fit	7.79	ENSMUST00000139259.2 ENSMUST00000060013.4	Gm6377 Links Ensembl NCBI MGI UniProt Show fit	predicted gene 6377
chr9_+_106099797 Show fit	7.57	ENSMUST00000062241.11	Tlr9 Links Ensembl NCBI MGI UniProt Show fit	toll-like receptor 9
chr19_-_5711650 Show fit	7.54	ENSMUST00000236006.2	Sipa1 Links Ensembl NCBI MGI UniProt Show fit	signal-induced proliferation associated gene 1
chr2_-_6726417 Show fit	7.45	ENSMUST00000142941.8 ENSMUST00000150624.9 ENSMUST00000100429.11 ENSMUST00000182879.8	Celf2 Links Ensembl NCBI MGI UniProt Show fit	CUGBP, Elav-like family member 2
chr14_+_50595361 Show fit	7.36	ENSMUST00000185091.2	Tlr11 Links Ensembl NCBI MGI UniProt Show fit	toll-like receptor 11
chr7_+_24310738 Show fit	7.34	ENSMUST00000073325.6	Phldb3 Links Ensembl NCBI MGI UniProt Show fit	pleckstrin homology like domain, family B, member 3
chr19_-_8751795 Show fit	7.22	ENSMUST00000010249.7	Tmem179b Links Ensembl NCBI MGI UniProt Show fit	transmembrane protein 179B
chr4_-_136620376 Show fit	7.20	ENSMUST00000046332.6	C1qc Links Ensembl NCBI MGI UniProt Show fit	complement component 1, q subcomponent, C chain
chr7_-_28931873 Show fit	7.19	ENSMUST00000085818.6	Kcnk6 Links Ensembl NCBI MGI UniProt Show fit	potassium inwardly-rectifying channel, subfamily K, member 6
chrX_-_93166992 Show fit	7.15	ENSMUST00000088102.12 ENSMUST00000113927.8	Zfx Links Ensembl NCBI MGI UniProt Show fit	zinc finger protein X-linked
chr7_+_75259778 Show fit	7.10	ENSMUST00000207923.2	Akap13 Links Ensembl NCBI MGI UniProt Show fit	A kinase (PRKA) anchor protein 13
chr11_+_54517164 Show fit	7.10	ENSMUST00000239168.2	Rapgef6 Links Ensembl NCBI MGI UniProt Show fit	Rap guanine nucleotide exchange factor (GEF) 6
chr2_-_60793536 Show fit	7.08	ENSMUST00000028347.13	Rbms1 Links Ensembl NCBI MGI UniProt Show fit	RNA binding motif, single stranded interacting protein 1
chr1_+_52158599 Show fit	7.04	ENSMUST00000186574.7 ENSMUST00000070968.14 ENSMUST00000191435.7 ENSMUST00000186857.7 ENSMUST00000188681.7	Stat1 Links Ensembl NCBI MGI UniProt Show fit	signal transducer and activator of transcription 1
chr11_+_70057449 Show fit	7.02	ENSMUST00000102571.10 ENSMUST00000178945.8 ENSMUST00000000327.13 ENSMUST00000178567.3	Clec10a Links Ensembl NCBI MGI UniProt Show fit	C-type lectin domain family 10, member A
chr9_-_70410611 Show fit	7.01	ENSMUST00000215848.2 ENSMUST00000113595.2 ENSMUST00000213647.2	Rnf111 Links Ensembl NCBI MGI UniProt Show fit	ring finger 111
chr12_-_79027531 Show fit	6.99	ENSMUST00000174072.8	Tmem229b Links Ensembl NCBI MGI UniProt Show fit	transmembrane protein 229B
chr1_-_170803680 Show fit	6.97	ENSMUST00000027966.14 ENSMUST00000081103.12 ENSMUST00000159688.2	Fcgr2b Links Ensembl NCBI MGI UniProt Show fit	Fc receptor, IgG, low affinity IIb
chr12_-_28685913 Show fit	6.59	ENSMUST00000074267.5	Rps7 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein S7
chr1_-_170804116 Show fit	6.51	ENSMUST00000159969.8	Fcgr2b Links Ensembl NCBI MGI UniProt Show fit	Fc receptor, IgG, low affinity IIb
chr6_-_30304512 Show fit	6.49	ENSMUST00000094543.3 ENSMUST00000102993.10	Ube2h Links Ensembl NCBI MGI UniProt Show fit	ubiquitin-conjugating enzyme E2H
chr17_+_48539782 Show fit	6.45	ENSMUST00000113251.10 ENSMUST00000048782.7	Trem1 Links Ensembl NCBI MGI UniProt Show fit	triggering receptor expressed on myeloid cells 1
chr2_+_163916042 Show fit	6.41	ENSMUST00000018353.14	Stk4 Links Ensembl NCBI MGI UniProt Show fit	serine/threonine kinase 4
chr19_+_46293160 Show fit	6.36	ENSMUST00000073116.13	Nfkb2 Links Ensembl NCBI MGI UniProt Show fit	nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr1_-_125362321 Show fit	6.28	ENSMUST00000191544.7	Actr3 Links Ensembl NCBI MGI UniProt Show fit	ARP3 actin-related protein 3
chr18_+_75133519 Show fit	6.27	ENSMUST00000079716.6	Rpl17 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein L17
chr13_-_13568106 Show fit	6.25	ENSMUST00000021738.10 ENSMUST00000220628.2	Gpr137b Links Ensembl NCBI MGI UniProt Show fit	G protein-coupled receptor 137B
chr9_+_64718596 Show fit	6.21	ENSMUST00000038890.6	Dennd4a Links Ensembl NCBI MGI UniProt Show fit	DENN/MADD domain containing 4A
chr5_+_123280250 Show fit	6.20	ENSMUST00000174836.8 ENSMUST00000163030.9	Setd1b Links Ensembl NCBI MGI UniProt Show fit	SET domain containing 1B
chrX_+_41238193 Show fit	6.16	ENSMUST00000115073.9 ENSMUST00000115072.8	Stag2 Links Ensembl NCBI MGI UniProt Show fit	stromal antigen 2
chr10_-_88192852 Show fit	6.10	ENSMUST00000020249.2	Dram1 Links Ensembl NCBI MGI UniProt Show fit	DNA-damage regulated autophagy modulator 1
chr1_+_52158721 Show fit	6.08	ENSMUST00000186057.7	Stat1 Links Ensembl NCBI MGI UniProt Show fit	signal transducer and activator of transcription 1
chr4_+_11579648 Show fit	6.03	ENSMUST00000180239.2	Fsbp Links Ensembl NCBI MGI UniProt Show fit	fibrinogen silencer binding protein
chr6_+_15727798 Show fit	5.95	ENSMUST00000128849.3	Mdfic Links Ensembl NCBI MGI UniProt Show fit	MyoD family inhibitor domain containing
chr10_-_62343876 Show fit	5.94	ENSMUST00000159020.2	Srgn Links Ensembl NCBI MGI UniProt Show fit	serglycin
chr1_+_52158693 Show fit	5.89	ENSMUST00000189347.7	Stat1 Links Ensembl NCBI MGI UniProt Show fit	signal transducer and activator of transcription 1
chr2_-_129151882 Show fit	5.80	ENSMUST00000028882.2	Il1a Links Ensembl NCBI MGI UniProt Show fit	interleukin 1 alpha
chr9_-_70411000 Show fit	5.76	ENSMUST00000034739.12	Rnf111 Links Ensembl NCBI MGI UniProt Show fit	ring finger 111

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
18.5	55.6	GO:0002277	myeloid dendritic cell activation involved in immune response(GO:0002277)
11.5	34.6	GO:0045660	positive regulation of neutrophil differentiation(GO:0045660)
10.1	30.4	GO:0010387	COP9 signalosome assembly(GO:0010387)
9.3	27.8	GO:0060305	regulation of inositol-polyphosphate 5-phosphatase activity(GO:0010924) positive regulation of inositol-polyphosphate 5-phosphatase activity(GO:0010925) phospholipase C-inhibiting G-protein coupled receptor signaling pathway(GO:0030845) regulation of cell diameter(GO:0060305)
8.8	70.7	GO:0032796	uropod organization(GO:0032796)
8.5	93.6	GO:0030886	negative regulation of myeloid dendritic cell activation(GO:0030886)
8.5	76.5	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
7.5	22.4	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
7.2	35.9	GO:0001803	type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
7.1	21.2	GO:0070947	neutrophil mediated killing of fungus(GO:0070947)
6.8	20.3	GO:1903972	regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
6.8	20.3	GO:0035771	interleukin-4-mediated signaling pathway(GO:0035771)
6.3	19.0	GO:0034240	negative regulation of macrophage fusion(GO:0034240)
6.3	37.9	GO:0002540	leukotriene production involved in inflammatory response(GO:0002540)
6.0	24.2	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
5.8	28.9	GO:0002434	immune complex clearance(GO:0002434)
5.2	20.9	GO:0002337	B-1a B cell differentiation(GO:0002337)
4.5	18.0	GO:0071477	hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
4.4	13.2	GO:0072356	chromosome passenger complex localization to kinetochore(GO:0072356)
4.3	34.1	GO:0033277	abortive mitotic cell cycle(GO:0033277)
4.1	32.8	GO:0010897	negative regulation of triglyceride catabolic process(GO:0010897)
4.0	27.7	GO:0035696	monocyte extravasation(GO:0035696)
3.6	14.6	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536)
3.5	21.1	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902)
3.2	28.7	GO:0046874	quinolinate metabolic process(GO:0046874)
3.2	19.1	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
3.1	9.4	GO:0072355	histone H3-T3 phosphorylation(GO:0072355)
3.0	45.2	GO:0002551	mast cell chemotaxis(GO:0002551)
3.0	15.1	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
2.9	17.4	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
2.8	8.5	GO:0014739	positive regulation of muscle hyperplasia(GO:0014739)
2.8	8.4	GO:0045083	negative regulation of interleukin-12 biosynthetic process(GO:0045083) response to diterpene(GO:1904629) cellular response to diterpene(GO:1904630) response to glucoside(GO:1904631) cellular response to glucoside(GO:1904632)
2.8	19.4	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
2.6	10.3	GO:0015910	peroxisomal long-chain fatty acid import(GO:0015910)
2.5	7.6	GO:0032741	positive regulation of interleukin-18 production(GO:0032741)
2.5	9.9	GO:0045659	negative regulation of neutrophil differentiation(GO:0045659)
2.4	12.0	GO:0002485	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
2.3	11.4	GO:0034421	post-translational protein acetylation(GO:0034421)
2.2	10.9	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
2.2	32.6	GO:0002227	innate immune response in mucosa(GO:0002227)
2.2	13.0	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
2.1	12.8	GO:0002248	connective tissue replacement involved in inflammatory response wound healing(GO:0002248)
2.0	20.4	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
2.0	22.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
1.9	9.4	GO:0034085	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
1.8	57.3	GO:0032060	bleb assembly(GO:0032060)
1.8	21.9	GO:0002667	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
1.8	5.4	GO:0001966	thigmotaxis(GO:0001966)
1.7	11.9	GO:2000623	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
1.7	16.8	GO:0032074	negative regulation of nuclease activity(GO:0032074)
1.6	14.7	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
1.6	8.0	GO:0031296	B cell costimulation(GO:0031296)
1.6	6.4	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
1.6	6.4	GO:0002266	follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
1.5	7.5	GO:0042631	cellular response to water deprivation(GO:0042631)
1.5	5.9	GO:0033371	protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382)
1.5	47.0	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
1.4	4.3	GO:0001812	positive regulation of type I hypersensitivity(GO:0001812)
1.4	8.4	GO:1901668	regulation of superoxide dismutase activity(GO:1901668)
1.3	5.4	GO:0072717	cellular response to actinomycin D(GO:0072717)
1.3	12.8	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
1.3	2.5	GO:0038096	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
1.3	8.8	GO:0002457	T cell antigen processing and presentation(GO:0002457)
1.2	21.2	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
1.1	29.7	GO:0032674	regulation of interleukin-5 production(GO:0032674)
1.1	22.8	GO:0071803	positive regulation of podosome assembly(GO:0071803)
1.1	15.9	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
1.1	5.6	GO:0032917	polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
1.1	11.0	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
1.1	6.4	GO:0070945	neutrophil mediated killing of gram-negative bacterium(GO:0070945)
1.0	16.7	GO:0001771	immunological synapse formation(GO:0001771)
1.0	7.2	GO:0030853	negative regulation of granulocyte differentiation(GO:0030853)
1.0	7.2	GO:0060075	regulation of resting membrane potential(GO:0060075)
1.0	3.0	GO:0002426	immunoglobulin production in mucosal tissue(GO:0002426)
1.0	8.7	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
1.0	8.7	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.9	5.4	GO:2000354	regulation of ovarian follicle development(GO:2000354)
0.9	7.1	GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.9	31.6	GO:0032012	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.9	18.2	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.9	16.4	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.9	9.4	GO:0075509	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.8	9.8	GO:1990118	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.8	8.0	GO:0032532	regulation of microvillus length(GO:0032532)
0.8	3.1	GO:1905053	regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.8	74.2	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.8	11.3	GO:1902947	regulation of tau-protein kinase activity(GO:1902947)
0.7	5.1	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.7	2.9	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.7	7.9	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.7	8.7	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.7	10.0	GO:0032494	response to peptidoglycan(GO:0032494)
0.6	4.3	GO:0090383	phagosome acidification(GO:0090383)
0.6	18.2	GO:0007194	negative regulation of adenylate cyclase activity(GO:0007194)
0.6	26.4	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.6	2.3	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.6	3.9	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.6	5.0	GO:1902410	mitotic cytokinetic process(GO:1902410)
0.5	37.0	GO:0045576	mast cell activation(GO:0045576)
0.5	5.7	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.5	2.5	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.5	1.5	GO:0033082	regulation of extrathymic T cell differentiation(GO:0033082)
0.5	22.2	GO:0043551	regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.5	3.3	GO:0007256	activation of JNKK activity(GO:0007256)
0.5	2.3	GO:1900157	regulation of bone mineralization involved in bone maturation(GO:1900157)
0.5	13.4	GO:0060746	parental behavior(GO:0060746)
0.5	4.6	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.5	20.8	GO:0035329	hippo signaling(GO:0035329)
0.4	3.6	GO:0000821	regulation of arginine metabolic process(GO:0000821)
0.4	38.5	GO:0071277	cellular response to calcium ion(GO:0071277)
0.4	3.8	GO:0090400	stress-induced premature senescence(GO:0090400)
0.4	4.2	GO:0002634	regulation of germinal center formation(GO:0002634)
0.4	9.1	GO:0008340	determination of adult lifespan(GO:0008340)
0.4	24.6	GO:0046579	positive regulation of Ras protein signal transduction(GO:0046579)
0.4	5.7	GO:0070933	histone H4 deacetylation(GO:0070933)
0.4	17.8	GO:0006376	mRNA splice site selection(GO:0006376)
0.3	9.7	GO:0002763	positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.3	5.7	GO:0032099	negative regulation of appetite(GO:0032099)
0.3	13.6	GO:0070098	chemokine-mediated signaling pathway(GO:0070098)
0.3	4.1	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
0.3	10.0	GO:0006903	vesicle targeting(GO:0006903)
0.3	8.5	GO:0030903	notochord development(GO:0030903)
0.3	89.5	GO:0019221	cytokine-mediated signaling pathway(GO:0019221)
0.3	7.1	GO:0030033	microvillus assembly(GO:0030033)
0.3	7.8	GO:0044342	type B pancreatic cell proliferation(GO:0044342)
0.2	3.3	GO:1902916	positive regulation of protein polyubiquitination(GO:1902916)
0.2	0.7	GO:0060125	amylase secretion(GO:0036394) pancreatic amylase secretion(GO:0036395) negative regulation of growth hormone secretion(GO:0060125) regulation of pancreatic amylase secretion(GO:1902276) negative regulation of pancreatic amylase secretion(GO:1902277)
0.2	6.0	GO:0050434	positive regulation of viral transcription(GO:0050434)
0.2	15.2	GO:1902476	chloride transmembrane transport(GO:1902476)
0.2	0.6	GO:1903027	regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.2	1.0	GO:0071894	histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.2	5.5	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.2	6.7	GO:0000731	DNA synthesis involved in DNA repair(GO:0000731)
0.2	12.8	GO:0048146	positive regulation of fibroblast proliferation(GO:0048146)
0.2	38.3	GO:1990830	response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.2	6.5	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.1	3.0	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.1	2.7	GO:0010592	positive regulation of lamellipodium assembly(GO:0010592)
0.1	4.4	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.1	2.5	GO:0071712	ER-associated misfolded protein catabolic process(GO:0071712)
0.1	1.6	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.1	3.8	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.1	10.6	GO:0031397	negative regulation of protein ubiquitination(GO:0031397)
0.1	1.9	GO:0010835	regulation of protein ADP-ribosylation(GO:0010835)
0.1	1.6	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.1	5.1	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1	7.0	GO:0034612	response to tumor necrosis factor(GO:0034612)
0.1	0.5	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.1	15.8	GO:0000910	cytokinesis(GO:0000910)
0.1	3.4	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1	3.7	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1	0.7	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.1	14.4	GO:0002244	hematopoietic progenitor cell differentiation(GO:0002244)
0.1	0.6	GO:0039536	choline transport(GO:0015871) negative regulation of RIG-I signaling pathway(GO:0039536)
0.1	2.8	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.1	2.0	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.1	1.0	GO:1903504	regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1	1.9	GO:0046653	tetrahydrofolate metabolic process(GO:0046653)
0.1	1.7	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.1	8.0	GO:0044264	cellular polysaccharide metabolic process(GO:0044264)
0.1	0.9	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.1	0.5	GO:0005513	detection of calcium ion(GO:0005513)
0.1	8.0	GO:0006958	complement activation, classical pathway(GO:0006958)
0.0	0.5	GO:0031507	heterochromatin assembly(GO:0031507)
0.0	1.3	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.1	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0	0.7	GO:0002115	store-operated calcium entry(GO:0002115)
0.0	6.4	GO:0010506	regulation of autophagy(GO:0010506)
0.0	0.2	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
0.0	2.6	GO:0007098	centrosome cycle(GO:0007098)
0.0	5.2	GO:0006898	receptor-mediated endocytosis(GO:0006898)
0.0	0.3	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0	1.4	GO:0098656	anion transmembrane transport(GO:0098656)
0.0	1.9	GO:0042113	B cell activation(GO:0042113)
0.0	1.7	GO:0051607	defense response to virus(GO:0051607)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
11.0	55.0	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
5.7	17.2	GO:0032998	Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
3.5	27.8	GO:0005826	actomyosin contractile ring(GO:0005826)
3.2	104.6	GO:0001891	phagocytic cup(GO:0001891)
2.8	34.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
2.3	45.9	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
2.0	107.9	GO:0001772	immunological synapse(GO:0001772)
1.8	16.4	GO:0070436	Grb2-EGFR complex(GO:0070436)
1.8	19.4	GO:0042101	T cell receptor complex(GO:0042101)
1.7	8.4	GO:1990130	Iml1 complex(GO:1990130)
1.6	24.1	GO:0031209	SCAR complex(GO:0031209)
1.5	19.6	GO:0000788	nuclear nucleosome(GO:0000788)
1.3	6.7	GO:0043625	delta DNA polymerase complex(GO:0043625)
1.3	21.2	GO:0043020	NADPH oxidase complex(GO:0043020)
1.3	6.4	GO:0033257	Bcl3/NF-kappaB2 complex(GO:0033257)
1.3	3.8	GO:0032156	septin cytoskeleton(GO:0032156)
1.3	7.6	GO:0036019	endolysosome(GO:0036019)
1.1	8.4	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.9	12.0	GO:0042612	MHC class I protein complex(GO:0042612)
0.8	52.6	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.8	9.4	GO:0008278	cohesin complex(GO:0008278)
0.6	4.4	GO:0072487	MSL complex(GO:0072487)
0.6	30.4	GO:0008180	COP9 signalosome(GO:0008180)
0.6	13.2	GO:1990023	mitotic spindle midzone(GO:1990023)
0.5	5.4	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.5	5.9	GO:0042629	mast cell granule(GO:0042629)
0.5	8.8	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
0.5	68.7	GO:0030136	clathrin-coated vesicle(GO:0030136)
0.5	11.9	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.5	9.0	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.4	82.9	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.4	55.9	GO:0032587	ruffle membrane(GO:0032587)
0.4	1.6	GO:0002111	BRCA2-BRAF35 complex(GO:0002111)
0.4	25.4	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.3	10.3	GO:0005779	integral component of peroxisomal membrane(GO:0005779)
0.3	20.9	GO:0045335	phagocytic vesicle(GO:0045335)
0.3	21.0	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.3	13.7	GO:0031901	early endosome membrane(GO:0031901)
0.2	3.4	GO:0042581	specific granule(GO:0042581)
0.2	2.7	GO:0044666	MLL3/4 complex(GO:0044666)
0.2	15.2	GO:0034707	chloride channel complex(GO:0034707)
0.2	94.2	GO:0009897	external side of plasma membrane(GO:0009897)
0.2	0.7	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.2	2.9	GO:0030127	COPII vesicle coat(GO:0030127)
0.2	1.8	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1	2.3	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.1	29.2	GO:0005923	bicellular tight junction(GO:0005923)
0.1	0.1	GO:0032593	insulin-responsive compartment(GO:0032593)
0.1	4.1	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.1	15.2	GO:0005581	collagen trimer(GO:0005581)
0.1	21.5	GO:0030863	cortical cytoskeleton(GO:0030863)
0.1	24.2	GO:0030027	lamellipodium(GO:0030027)
0.1	10.6	GO:0045177	apical part of cell(GO:0045177)
0.1	5.7	GO:0035861	site of double-strand break(GO:0035861)
0.1	7.1	GO:0030139	endocytic vesicle(GO:0030139)
0.1	3.1	GO:0005685	U1 snRNP(GO:0005685)
0.1	6.2	GO:0008023	transcription elongation factor complex(GO:0008023)
0.1	9.2	GO:0016323	basolateral plasma membrane(GO:0016323)
0.1	21.3	GO:0045121	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1	7.0	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.1	3.7	GO:0035145	exon-exon junction complex(GO:0035145)
0.1	8.4	GO:0005795	Golgi stack(GO:0005795)
0.1	25.9	GO:0005911	cell-cell junction(GO:0005911)
0.1	1.5	GO:0031143	pseudopodium(GO:0031143)
0.1	28.9	GO:0031965	nuclear membrane(GO:0031965)
0.1	141.6	GO:0005887	integral component of plasma membrane(GO:0005887)
0.1	1.5	GO:0030315	T-tubule(GO:0030315)
0.1	7.0	GO:0055037	recycling endosome(GO:0055037)
0.1	1.0	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1	41.3	GO:0000785	chromatin(GO:0000785)
0.1	9.5	GO:0000776	kinetochore(GO:0000776)
0.0	4.4	GO:0031252	cell leading edge(GO:0031252)
0.0	1.0	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	230.9	GO:0016021	integral component of membrane(GO:0016021)
0.0	139.7	GO:0005829	cytosol(GO:0005829)
0.0	0.6	GO:0005903	brush border(GO:0005903)
0.0	3.0	GO:0031012	extracellular matrix(GO:0031012)
0.0	13.9	GO:0005615	extracellular space(GO:0005615)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.5	76.5	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
7.6	37.9	GO:0004051	arachidonate 5-lipoxygenase activity(GO:0004051)
6.8	20.3	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
5.4	21.6	GO:0019767	IgE receptor activity(GO:0019767)
5.1	15.4	GO:0035717	chemokine (C-C motif) ligand 7 binding(GO:0035717)
5.1	20.3	GO:0005136	interleukin-4 receptor binding(GO:0005136)
4.6	32.2	GO:0019770	IgG receptor activity(GO:0019770)
4.5	18.0	GO:0035827	rubidium ion transmembrane transporter activity(GO:0035827)
3.4	70.7	GO:0032036	myosin heavy chain binding(GO:0032036)
3.1	9.4	GO:0035175	histone kinase activity (H3-S10 specific)(GO:0035175)
2.7	10.9	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
2.6	34.1	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
2.5	32.8	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
2.5	22.2	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
2.4	47.7	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
2.4	21.3	GO:1990948	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
1.8	20.1	GO:0019957	C-C chemokine binding(GO:0019957)
1.7	43.3	GO:0042608	T cell receptor binding(GO:0042608)
1.6	103.3	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
1.6	21.2	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
1.6	12.8	GO:0032184	SUMO polymer binding(GO:0032184)
1.6	19.0	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
1.4	8.7	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
1.4	5.6	GO:0019809	spermidine binding(GO:0019809)
1.4	46.5	GO:0008187	poly-pyrimidine tract binding(GO:0008187)
1.3	7.6	GO:0045322	unmethylated CpG binding(GO:0045322)
1.2	9.9	GO:0051425	inositol bisphosphate phosphatase activity(GO:0016312) PTB domain binding(GO:0051425)
1.2	151.2	GO:0004896	cytokine receptor activity(GO:0004896)
1.1	10.3	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
1.0	6.3	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
1.0	11.4	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
1.0	3.1	GO:0097100	supercoiled DNA binding(GO:0097100)
1.0	15.1	GO:0051525	NFAT protein binding(GO:0051525)
1.0	66.5	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
1.0	9.8	GO:0015386	potassium:proton antiporter activity(GO:0015386)
1.0	25.2	GO:0019825	oxygen binding(GO:0019825)
0.9	3.5	GO:0016822	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.9	40.3	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.8	9.1	GO:0036310	annealing helicase activity(GO:0036310)
0.8	31.6	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.8	25.9	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.6	13.0	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.6	7.1	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.6	10.0	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.6	7.5	GO:0001069	regulatory region RNA binding(GO:0001069)
0.5	3.3	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.5	13.6	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.5	1.5	GO:0031896	V2 vasopressin receptor binding(GO:0031896)
0.4	1.7	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.4	31.3	GO:0016278	lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.3	27.1	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.3	7.2	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.3	21.2	GO:0016860	intramolecular oxidoreductase activity(GO:0016860)
0.3	94.0	GO:0005085	guanyl-nucleotide exchange factor activity(GO:0005085)
0.3	1.9	GO:0004487	methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.3	12.9	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.3	6.0	GO:0030957	Tat protein binding(GO:0030957)
0.3	1.9	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.3	13.8	GO:0001786	phosphatidylserine binding(GO:0001786)
0.3	5.8	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.3	1.0	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.3	8.7	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.2	5.0	GO:0050811	GABA receptor binding(GO:0050811)
0.2	3.8	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2	11.1	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.2	45.0	GO:0019903	protein phosphatase binding(GO:0019903)
0.2	8.1	GO:0042056	chemoattractant activity(GO:0042056)
0.2	21.4	GO:0030295	protein kinase activator activity(GO:0030295)
0.2	15.8	GO:0019902	phosphatase binding(GO:0019902)
0.2	7.2	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.2	6.7	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.2	8.0	GO:0003785	actin monomer binding(GO:0003785)
0.2	3.6	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.2	3.9	GO:0005537	mannose binding(GO:0005537)
0.2	8.8	GO:0048365	Rac GTPase binding(GO:0048365)
0.2	8.5	GO:0005504	fatty acid binding(GO:0005504)
0.1	2.3	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1	0.7	GO:0019209	kinase activator activity(GO:0019209)
0.1	2.3	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.1	3.2	GO:0035613	RNA stem-loop binding(GO:0035613)
0.1	1.4	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.1	7.0	GO:0036002	pre-mRNA binding(GO:0036002)
0.1	35.3	GO:0051015	actin filament binding(GO:0051015)
0.1	25.6	GO:0003735	structural constituent of ribosome(GO:0003735)
0.1	4.9	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1	19.5	GO:0005178	integrin binding(GO:0005178)
0.1	4.4	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1	8.4	GO:0042805	actinin binding(GO:0042805)
0.1	9.4	GO:0031593	polyubiquitin binding(GO:0031593)
0.1	6.5	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.1	15.2	GO:0005254	chloride channel activity(GO:0005254)
0.1	22.9	GO:0003823	antigen binding(GO:0003823)
0.1	35.9	GO:0030246	carbohydrate binding(GO:0030246)
0.1	3.3	GO:0017075	syntaxin-1 binding(GO:0017075)
0.1	1.5	GO:0031432	titin binding(GO:0031432)
0.1	10.3	GO:0003725	double-stranded RNA binding(GO:0003725)
0.1	3.1	GO:0070064	proline-rich region binding(GO:0070064)
0.1	20.9	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.1	4.1	GO:0032452	histone demethylase activity(GO:0032452)
0.1	15.8	GO:0005125	cytokine activity(GO:0005125)
0.1	6.4	GO:0097110	scaffold protein binding(GO:0097110)
0.1	1.6	GO:0000400	four-way junction DNA binding(GO:0000400)
0.1	27.3	GO:0005096	GTPase activator activity(GO:0005096)
0.1	2.8	GO:0017048	Rho GTPase binding(GO:0017048)
0.1	5.9	GO:0005518	collagen binding(GO:0005518)
0.1	5.3	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1	1.2	GO:0008179	adenylate cyclase binding(GO:0008179)
0.1	2.3	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.1	5.8	GO:0008083	growth factor activity(GO:0008083)
0.1	9.1	GO:0019887	protein kinase regulator activity(GO:0019887)
0.1	0.7	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	2.0	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0	8.0	GO:0052689	carboxylic ester hydrolase activity(GO:0052689)
0.0	8.0	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	4.0	GO:0004386	helicase activity(GO:0004386)
0.0	0.3	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.1	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.5	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.2	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.3	112.2	PID IL5 PATHWAY	IL5-mediated signaling events
2.1	19.0	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
1.6	120.1	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
1.5	88.1	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
1.3	87.8	PID BCR 5PATHWAY	BCR signaling pathway
1.0	22.2	PID EPHA FWDPATHWAY	EPHA forward signaling
0.9	22.6	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.9	89.0	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.8	71.3	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.7	23.1	PID RAS PATHWAY	Regulation of Ras family activation
0.7	38.7	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.7	13.6	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.6	37.7	PID IL12 2PATHWAY	IL12-mediated signaling events
0.6	37.5	PID IL4 2PATHWAY	IL4-mediated signaling events
0.6	16.7	PID IL1 PATHWAY	IL1-mediated signaling events
0.5	43.7	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.5	5.4	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.4	29.9	PID RAC1 PATHWAY	RAC1 signaling pathway
0.4	20.8	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.4	11.9	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.4	9.9	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.3	20.6	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2	10.7	PID TNF PATHWAY	TNF receptor signaling pathway
0.2	5.6	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.2	11.0	PID PLK1 PATHWAY	PLK1 signaling events
0.2	3.8	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.2	12.8	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.1	29.5	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	5.9	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	2.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	4.6	PID ILK PATHWAY	Integrin-linked kinase signaling
0.1	1.0	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	11.4	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.1	2.3	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.1	3.1	PID AURORA A PATHWAY	Aurora A signaling
0.1	6.0	PID P53 REGULATION PATHWAY	p53 pathway
0.0	17.1	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	1.2	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	5.7	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	1.1	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	3.0	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.2	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.4	64.7	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
2.7	47.7	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
2.4	28.7	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
2.4	97.4	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
2.4	129.9	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
2.1	28.7	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
1.9	15.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
1.7	27.8	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
1.7	15.4	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
1.5	57.0	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
1.5	19.0	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
1.2	8.7	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
1.0	40.1	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.8	26.2	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.8	66.5	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.8	27.2	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.8	50.1	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.7	11.5	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.7	11.9	REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.7	33.7	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.7	32.4	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.6	7.6	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.6	21.2	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.5	6.7	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.5	5.4	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.5	6.4	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.5	10.7	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.5	16.0	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.4	7.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.4	91.8	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.4	10.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.4	35.5	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.4	7.5	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.3	33.8	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.3	16.7	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.3	13.5	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.3	21.0	REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION	Genes involved in 3' -UTR-mediated translational regulation
0.3	6.3	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.3	5.4	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.3	21.8	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.2	11.0	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.2	4.6	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.2	27.8	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2	1.5	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.2	2.9	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1	3.7	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1	5.5	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1	11.8	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.1	3.0	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1	1.7	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	8.7	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.7	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.6	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	1.9	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
0.0	0.5	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.5	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	2.5	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation