Project

PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

Navigation
Downloads

Results for Spic

Z-value: 3.42

Motif logo

Transcription factors associated with Spic

Gene Symbol Gene ID Gene Info
ENSMUSG00000004359.17 Spic

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Spicmm39_v1_chr10_-_88518878_885188920.832.9e-19Click!

Activity profile of Spic motif

Sorted Z-values of Spic motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Spic

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image
Promoter Score Transcript Gene Gene Info
chr6_-_136918671 28.13 ENSMUST00000032344.12
Rho, GDP dissociation inhibitor (GDI) beta
chr6_-_136918844 27.99 ENSMUST00000204934.2
Rho, GDP dissociation inhibitor (GDI) beta
chr7_+_43057611 25.61 ENSMUST00000005592.7
sialic acid binding Ig-like lectin G
chr7_-_126303351 25.35 ENSMUST00000106364.8
coronin, actin binding protein 1A
chrX_+_106132840 23.66 ENSMUST00000118666.8
ENSMUST00000053375.4
purinergic receptor P2Y, G-protein coupled 10
chr11_-_79414542 23.63 ENSMUST00000179322.2
ecotropic viral integration site 2b
chr7_-_126303887 23.53 ENSMUST00000131415.8
coronin, actin binding protein 1A
chr7_+_28682253 22.20 ENSMUST00000085835.8
mitogen-activated protein kinase kinase kinase kinase 1
chr4_+_130640436 22.13 ENSMUST00000151698.8
lysosomal-associated protein transmembrane 5
chr11_-_115024807 21.89 ENSMUST00000106561.8
ENSMUST00000051264.14
ENSMUST00000106562.3
CD300 molecule like family member F
chr6_-_136918885 21.86 ENSMUST00000111891.4
Rho, GDP dissociation inhibitor (GDI) beta
chr7_-_44888220 21.58 ENSMUST00000210372.2
ENSMUST00000209779.2
ENSMUST00000098461.10
ENSMUST00000211373.2
CD37 antigen
chr12_+_98234884 21.47 ENSMUST00000075072.6
G-protein coupled receptor 65
chr6_+_48661503 21.34 ENSMUST00000067506.14
ENSMUST00000119575.8
ENSMUST00000121957.8
ENSMUST00000090070.6
GTPase, IMAP family member 4
chr16_-_75706161 21.24 ENSMUST00000114239.9
SAM domain, SH3 domain and nuclear localization signals, 1
chr1_-_144651157 20.37 ENSMUST00000027603.4
regulator of G-protein signaling 18
chr7_+_28140352 20.01 ENSMUST00000078845.13
glia maturation factor, gamma
chr6_-_48685108 19.92 ENSMUST00000126422.3
ENSMUST00000119315.2
ENSMUST00000053661.7
GTPase, IMAP family member 6
chr4_+_138503046 19.77 ENSMUST00000030528.9
phospholipase A2, group IID
chr1_+_171723231 19.68 ENSMUST00000097466.3
predicted gene 10521
chr8_-_123159639 19.19 ENSMUST00000212600.2
cytochrome b-245, alpha polypeptide
chr15_+_78128990 19.15 ENSMUST00000096357.12
neutrophil cytosolic factor 4
chr3_+_87283687 19.08 ENSMUST00000163661.8
ENSMUST00000072480.9
Fc receptor-like 1
chr7_-_126303689 18.77 ENSMUST00000135087.8
coronin, actin binding protein 1A
chr7_+_142014546 18.67 ENSMUST00000105968.8
ENSMUST00000018963.11
ENSMUST00000105967.8
lymphocyte specific 1
chr7_-_121732067 18.45 ENSMUST00000106469.8
ENSMUST00000063587.13
ENSMUST00000106468.7
ENSMUST00000098068.10
partner and localizer of BRCA2
chr10_+_79715448 18.36 ENSMUST00000006679.15
proteinase 3
chr6_+_48661477 18.16 ENSMUST00000118802.8
GTPase, IMAP family member 4
chr2_+_43638814 17.98 ENSMUST00000112824.8
ENSMUST00000055776.8
Rho GTPase activating protein 15
chr3_-_106697459 17.87 ENSMUST00000038845.10
CD53 antigen
chr19_+_4204605 17.59 ENSMUST00000061086.9
protein tyrosine phosphatase, receptor type, C polypeptide-associated protein
chr17_+_57586094 17.26 ENSMUST00000169220.9
ENSMUST00000005889.16
ENSMUST00000112870.5
vav 1 oncogene
chr9_+_7558449 17.25 ENSMUST00000018765.4
matrix metallopeptidase 8
chr7_+_28140450 17.21 ENSMUST00000135686.2
glia maturation factor, gamma
chr6_+_41039255 17.17 ENSMUST00000103266.3
T cell receptor beta, variable 5
chr10_-_117118226 17.01 ENSMUST00000092163.9
lysozyme 2
chr6_-_70237939 16.88 ENSMUST00000103386.3
immunoglobulin kappa variable 6-23
chr9_-_20556031 16.85 ENSMUST00000148631.8
ENSMUST00000131128.2
ENSMUST00000151861.9
ENSMUST00000131343.8
ENSMUST00000086458.10
F-box and leucine-rich repeat protein 12
chr10_+_75778885 16.69 ENSMUST00000121151.2
pre-B lymphocyte gene 3
chr17_-_57385490 15.95 ENSMUST00000011623.9
DENN/MADD domain containing 1C
chr13_+_30933209 15.88 ENSMUST00000021784.10
ENSMUST00000110307.3
ENSMUST00000222125.2
interferon regulatory factor 4
chr6_+_70348416 15.78 ENSMUST00000103391.4
immunoglobulin kappa variable 6-17
chr8_+_95650315 15.65 ENSMUST00000153448.9
ENSMUST00000166802.9
ENSMUST00000074570.10
adhesion G protein-coupled receptor G5
chr7_-_19005721 15.63 ENSMUST00000032561.9
vasodilator-stimulated phosphoprotein
chr5_-_134258435 15.50 ENSMUST00000016094.13
ENSMUST00000111275.8
ENSMUST00000144086.2
neutrophil cytosolic factor 1
chr12_+_112727089 15.49 ENSMUST00000063888.5
phospholipase D family, member 4
chr6_-_70383976 15.42 ENSMUST00000103393.2
immunoglobulin kappa variable 6-15
chr9_+_123822000 15.41 ENSMUST00000039171.9
chemokine (C-C motif) receptor 3
chr9_+_88838953 15.35 ENSMUST00000098485.4
B cell leukemia/lymphoma 2 related protein A1a
chr11_+_98798627 15.30 ENSMUST00000092706.13
cell division cycle 6
chr6_+_129326927 15.25 ENSMUST00000065289.6
C-type lectin domain family 12, member a
chr4_+_130640611 14.93 ENSMUST00000156225.8
ENSMUST00000156742.8
lysosomal-associated protein transmembrane 5
chr5_+_149202157 14.92 ENSMUST00000200806.4
arachidonate 5-lipoxygenase activating protein
chr8_-_123159663 14.86 ENSMUST00000017604.10
cytochrome b-245, alpha polypeptide
chr5_+_149201577 14.75 ENSMUST00000071130.5
arachidonate 5-lipoxygenase activating protein
chr9_-_114610879 14.71 ENSMUST00000084867.9
ENSMUST00000216760.2
ENSMUST00000035009.16
CKLF-like MARVEL transmembrane domain containing 7
chr6_-_136918495 14.45 ENSMUST00000111892.8
Rho, GDP dissociation inhibitor (GDI) beta
chr5_+_66018555 14.44 ENSMUST00000031106.8
ras homolog family member H
chr7_-_44888532 14.43 ENSMUST00000033063.15
CD37 antigen
chr6_-_124715618 14.25 ENSMUST00000171549.9
protein tyrosine phosphatase, non-receptor type 6
chr15_+_78129040 14.07 ENSMUST00000133618.3
neutrophil cytosolic factor 4
chr7_+_126184108 14.06 ENSMUST00000039522.8
apolipoprotein B receptor
chr15_+_103362195 14.01 ENSMUST00000047405.9
NCK associated protein 1 like
chrX_+_106299484 13.96 ENSMUST00000101294.9
ENSMUST00000118820.8
ENSMUST00000120971.8
G protein-coupled receptor 174
chr3_-_105839980 13.96 ENSMUST00000098758.5
RIKEN cDNA I830077J02 gene
chr2_-_129213050 13.93 ENSMUST00000028881.14
interleukin 1 beta
chr13_+_102830029 13.78 ENSMUST00000022124.10
ENSMUST00000171267.2
ENSMUST00000167144.2
ENSMUST00000170878.2
CD180 antigen
chr10_+_130158737 13.66 ENSMUST00000217702.2
ENSMUST00000042586.10
ENSMUST00000218605.2
thymocyte expressed, positive selection associated 1
chr11_+_68322945 13.57 ENSMUST00000021283.8
phosphoinositide-3-kinase regulatory subunit 5
chr6_-_124715560 13.56 ENSMUST00000004377.15
protein tyrosine phosphatase, non-receptor type 6
chr9_+_89081262 13.24 ENSMUST00000068569.5
B cell leukemia/lymphoma 2 related protein A1b
chr17_+_29579882 13.10 ENSMUST00000024810.8
FYVE, RhoGEF and PH domain containing 2
chr6_-_124715542 13.09 ENSMUST00000174265.2
protein tyrosine phosphatase, non-receptor type 6
chr5_+_86219593 13.02 ENSMUST00000198435.5
ENSMUST00000031171.9
signal transducing adaptor family member 1
chr1_-_170755136 12.79 ENSMUST00000046322.14
ENSMUST00000159171.2
Fc receptor-like A
chr6_-_124710084 12.76 ENSMUST00000112484.10
protein tyrosine phosphatase, non-receptor type 6
chr7_-_44888465 12.75 ENSMUST00000210078.2
CD37 antigen
chr13_+_24685508 12.71 ENSMUST00000238974.2
RHO family interacting cell polarization regulator 2
chr19_+_6135013 12.60 ENSMUST00000025704.3
cell division cycle associated 5
chr6_+_41139948 12.60 ENSMUST00000103275.4
T cell receptor beta, variable 17
chr17_+_56056977 12.57 ENSMUST00000025004.7
adhesion G protein-coupled receptor E4
chr1_+_171668173 12.57 ENSMUST00000136479.8
CD84 antigen
chr2_+_152689881 12.47 ENSMUST00000164120.8
ENSMUST00000178997.8
ENSMUST00000109816.8
TPX2, microtubule-associated
chr19_+_24976864 12.43 ENSMUST00000025831.8
dedicator of cytokinesis 8
chr4_-_43454561 12.37 ENSMUST00000107926.8
ENSMUST00000107925.8
CD72 antigen
chr11_-_70703365 12.20 ENSMUST00000074572.7
ENSMUST00000108534.9
SLP adaptor and CSK interacting membrane protein
chr12_-_115611981 11.89 ENSMUST00000103540.3
ENSMUST00000199266.2
immunoglobulin heavy variable V8-12
chr11_-_82911615 11.87 ENSMUST00000038141.15
ENSMUST00000092838.11
schlafen 8
chr16_+_36755338 11.80 ENSMUST00000023531.15
hematopoietic cell specific Lyn substrate 1
chr6_+_123206802 11.64 ENSMUST00000112554.9
ENSMUST00000024118.11
ENSMUST00000117130.8
C-type lectin domain family 4, member n
chrX_-_165992311 11.54 ENSMUST00000112172.4
thymosin, beta 4, X chromosome
chr7_-_126641593 11.39 ENSMUST00000032915.8
kinesin family member 22
chr19_+_11352862 11.20 ENSMUST00000188995.2
membrane-spanning 4-domains, subfamily A, member 4A
chr11_-_16958647 11.20 ENSMUST00000102881.10
pleckstrin
chr19_+_12438125 11.10 ENSMUST00000081035.9
macrophage expressed gene 1
chr6_-_131224305 11.04 ENSMUST00000032306.15
ENSMUST00000088867.7
killer cell lectin-like receptor, subfamily A, member 2
chr1_+_40123858 10.93 ENSMUST00000027243.13
interleukin 1 receptor, type II
chr17_+_8144822 10.92 ENSMUST00000036370.8
T cell activation Rho GTPase activating protein
chr2_+_22664094 10.86 ENSMUST00000014290.15
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr14_-_56026266 10.73 ENSMUST00000168716.8
ENSMUST00000178399.3
ENSMUST00000022830.14
receptor-interacting serine-threonine kinase 3
chr3_-_95799242 10.54 ENSMUST00000171519.2
ENSMUST00000036360.13
ENSMUST00000090476.10
cDNA sequence BC028528
chr7_+_127661835 10.46 ENSMUST00000106242.10
ENSMUST00000120355.8
ENSMUST00000106240.9
ENSMUST00000098015.10
integrin alpha M
predicted gene, 49368
chr11_-_82911548 10.46 ENSMUST00000108152.9
schlafen 8
chr2_+_152689913 10.38 ENSMUST00000028969.9
TPX2, microtubule-associated
chr19_-_40982576 10.34 ENSMUST00000117695.8
B cell linker
chr1_+_152683627 10.33 ENSMUST00000027754.7
neutrophil cytosolic factor 2
chr11_+_87684299 10.32 ENSMUST00000020779.11
myeloperoxidase
chr7_-_104019046 10.30 ENSMUST00000106831.3
tripartite motif-containing 30B
chr6_-_124710030 10.28 ENSMUST00000173647.2
protein tyrosine phosphatase, non-receptor type 6
chr8_+_118225008 10.12 ENSMUST00000081232.9
phospholipase C, gamma 2
chr13_-_110493665 9.91 ENSMUST00000058806.7
ENSMUST00000224534.2
Grb2-binding adaptor, transmembrane
chr1_+_87548026 9.89 ENSMUST00000169754.8
ENSMUST00000042275.15
ENSMUST00000168783.8
inositol polyphosphate-5-phosphatase D
chrX_-_56371953 9.86 ENSMUST00000176986.8
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr11_-_82910912 9.79 ENSMUST00000130822.3
schlafen 8
chr13_-_97274360 9.59 ENSMUST00000225410.2
NSA2 ribosome biogenesis homolog
chr16_+_91203123 9.54 ENSMUST00000023691.12
interleukin 10 receptor, beta
chr13_-_49462694 9.37 ENSMUST00000110087.9
FYVE, RhoGEF and PH domain containing 3
chr7_+_127661807 9.37 ENSMUST00000064821.14
integrin alpha M
chr3_+_95566082 9.33 ENSMUST00000037947.15
ENSMUST00000178686.2
myeloid cell leukemia sequence 1
chr1_-_20890437 9.30 ENSMUST00000053266.11
minichromosome maintenance complex component 3
chr4_-_133601990 9.30 ENSMUST00000168974.9
ribosomal protein S6 kinase polypeptide 1
chr7_-_103964662 9.27 ENSMUST00000106837.8
ENSMUST00000106839.9
ENSMUST00000070943.7
tripartite motif-containing 12A
chr15_-_66684442 9.14 ENSMUST00000100572.10
src-like adaptor
chr19_+_11469386 9.08 ENSMUST00000079855.11
predicted gene 8369
chr1_-_170755109 8.88 ENSMUST00000162136.2
ENSMUST00000162887.2
Fc receptor-like A
chr10_-_17898838 8.81 ENSMUST00000220433.2
ABRA C-terminal like
chr7_-_4728081 8.63 ENSMUST00000086363.5
ENSMUST00000086364.11
transmembrane protein 150B
chr6_-_70364222 8.62 ENSMUST00000103392.3
ENSMUST00000195945.2
immunoglobulin kappa variable 8-16
chr1_-_144124871 8.60 ENSMUST00000189061.7
regulator of G-protein signaling 1
chr7_-_3918484 8.58 ENSMUST00000038176.15
ENSMUST00000206077.2
ENSMUST00000090689.5
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
chr8_+_85428059 8.57 ENSMUST00000238364.2
ENSMUST00000238562.2
ENSMUST00000037165.6
lymphoblastomic leukemia 1
chrX_-_20928219 8.56 ENSMUST00000040628.6
ENSMUST00000115333.9
ENSMUST00000115334.8
zinc finger protein 182
chr2_+_163916042 8.55 ENSMUST00000018353.14
serine/threonine kinase 4
chr3_+_87283767 8.54 ENSMUST00000194786.6
ENSMUST00000191666.2
Fc receptor-like 1
chr8_+_66838927 8.53 ENSMUST00000039540.12
ENSMUST00000110253.3
membrane associated ring-CH-type finger 1
chr7_-_103937301 8.46 ENSMUST00000098179.9
tripartite motif-containing 5
chr5_-_138169509 8.40 ENSMUST00000153867.8
minichromosome maintenance complex component 7
chr1_+_153628598 8.35 ENSMUST00000182538.3
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr6_-_130314465 8.33 ENSMUST00000088017.5
ENSMUST00000111998.9
killer cell lectin-like receptor, subfamily A, member 3
chr11_-_79418500 8.31 ENSMUST00000154415.2
ecotropic viral integration site 2a
chr6_+_123206880 8.29 ENSMUST00000205129.2
C-type lectin domain family 4, member n
chr13_-_97274430 8.25 ENSMUST00000073456.9
NSA2 ribosome biogenesis homolog
chrX_+_8137372 8.21 ENSMUST00000127103.8
ENSMUST00000115591.8
solute carrier family 38, member 5
chr3_+_87283748 8.16 ENSMUST00000167200.7
Fc receptor-like 1
chr4_+_11758147 7.96 ENSMUST00000029871.12
ENSMUST00000108303.2
cadherin 17
chr7_-_126641565 7.95 ENSMUST00000205806.2
kinesin family member 22
chr1_-_85239791 7.90 ENSMUST00000162421.2
RIKEN cDNA C130026I21 gene
chr4_-_136620376 7.86 ENSMUST00000046332.6
complement component 1, q subcomponent, C chain
chr7_-_104018989 7.84 ENSMUST00000164410.2
tripartite motif-containing 30B
chr6_-_56681657 7.74 ENSMUST00000176595.3
ENSMUST00000170382.5
ENSMUST00000203958.2
LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
chr15_-_63932176 7.72 ENSMUST00000226675.2
ENSMUST00000228226.2
ENSMUST00000227024.2
CYFIP related Rac1 interactor B
chr2_+_24235300 7.72 ENSMUST00000114485.9
ENSMUST00000114482.3
interleukin 1 receptor antagonist
chr7_-_43193842 7.72 ENSMUST00000039861.7
CD33 antigen
chr11_-_106606076 7.71 ENSMUST00000080853.11
ENSMUST00000183610.8
ENSMUST00000103069.10
ENSMUST00000106796.9
platelet/endothelial cell adhesion molecule 1
chr10_-_17898938 7.69 ENSMUST00000220110.2
ABRA C-terminal like
chr13_-_67508655 7.66 ENSMUST00000081582.8
zinc finger protein 953
chr9_+_89081407 7.60 ENSMUST00000138109.2
predicted gene 29094
chr10_-_17898977 7.59 ENSMUST00000020002.9
ABRA C-terminal like
chr14_-_47514308 7.58 ENSMUST00000111792.9
WD repeat and HMG-box DNA binding protein 1
chr3_-_100936859 7.38 ENSMUST00000147399.9
CD101 antigen
chr6_+_29529275 7.34 ENSMUST00000163511.7
interferon regulatory factor 5
chr1_+_152683568 7.28 ENSMUST00000190323.7
neutrophil cytosolic factor 2
chr4_-_86775602 7.26 ENSMUST00000102814.5
ribosomal protein S6
chr17_-_34174631 7.26 ENSMUST00000174609.9
ENSMUST00000008812.9
ribosomal protein S18
chr19_+_53517528 7.25 ENSMUST00000038287.7
dual specificity phosphatase 5
chr4_-_136626073 7.24 ENSMUST00000046285.6
complement component 1, q subcomponent, alpha polypeptide
chr14_-_47514248 7.23 ENSMUST00000187531.8
ENSMUST00000111790.2
WD repeat and HMG-box DNA binding protein 1
chrX_+_8137620 6.98 ENSMUST00000033512.11
solute carrier family 38, member 5
chr15_+_6599001 6.95 ENSMUST00000227175.2
FYN binding protein
chr6_-_70412460 6.84 ENSMUST00000103394.2
immunoglobulin kappa variable 6-14
chr15_-_78189917 6.84 ENSMUST00000096356.5
colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)
chr11_-_16952929 6.82 ENSMUST00000156101.2
pleckstrin
chr4_-_43454600 6.81 ENSMUST00000098105.4
ENSMUST00000098104.10
ENSMUST00000030179.11
CD72 antigen
chr5_+_4242367 6.78 ENSMUST00000177258.2
mitochondrial transcription termination factor 1b
chr10_+_115653152 6.76 ENSMUST00000080630.11
ENSMUST00000179196.3
ENSMUST00000035563.15
tetraspanin 8
chr14_+_53791444 6.70 ENSMUST00000198297.2
T cell receptor alpha variable 14-1
chr6_-_124888643 6.65 ENSMUST00000032217.2
lymphocyte-activation gene 3
chr17_+_47905553 6.64 ENSMUST00000182846.3
cyclin D3
chr4_+_140428777 6.64 ENSMUST00000138808.8
ENSMUST00000038893.6
regulator of chromosome condensation 2
chrX_-_100777806 6.52 ENSMUST00000056614.7
chemokine (C-X-C motif) receptor 3
chr5_-_138169253 6.48 ENSMUST00000139983.8
minichromosome maintenance complex component 7
chr3_+_89986831 6.46 ENSMUST00000029549.16
tropomyosin 3, gamma
chr4_-_136613498 6.43 ENSMUST00000046384.9
complement component 1, q subcomponent, beta polypeptide
chr18_-_35873257 6.30 ENSMUST00000235302.2
stimulator of interferon response cGAMP interactor 1
chr15_+_102368510 6.21 ENSMUST00000164688.2
proline rich 13
chr4_-_59549243 6.14 ENSMUST00000173699.8
ENSMUST00000173884.8
ENSMUST00000102883.11
ENSMUST00000174586.8
polypyrimidine tract binding protein 3
chr2_+_118943274 6.10 ENSMUST00000140939.8
ENSMUST00000028795.10
RAD51 recombinase
chr7_+_126184141 6.10 ENSMUST00000137646.8
apolipoprotein B receptor
chr13_-_58276353 5.98 ENSMUST00000007980.7
heterogeneous nuclear ribonucleoprotein A0
chr10_-_79938487 5.97 ENSMUST00000042771.8
strawberry notch 2
chr8_+_93581946 5.92 ENSMUST00000046290.3
ENSMUST00000210099.2
lysophosphatidylcholine acyltransferase 2
chr9_+_106099797 5.81 ENSMUST00000062241.11
toll-like receptor 9
chr14_+_80237691 5.76 ENSMUST00000228749.2
ENSMUST00000088735.4
olfactomedin 4
chr10_-_89279751 5.74 ENSMUST00000219351.2
ENSMUST00000220128.2
ENSMUST00000099374.9
ENSMUST00000105298.3
growth arrest-specific 2 like 3
chr19_+_4282040 5.66 ENSMUST00000237518.2
polymerase (DNA-directed), delta 4
chr1_+_72750418 5.64 ENSMUST00000059980.11
ribosomal protein L37a
chr1_-_149836974 5.63 ENSMUST00000190507.2
ENSMUST00000070200.15
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr13_-_67480588 5.60 ENSMUST00000109735.9
ENSMUST00000168892.9
zinc finger protein 595
chr1_-_144124787 5.60 ENSMUST00000185714.2
regulator of G-protein signaling 1
chr3_+_88528410 5.60 ENSMUST00000029694.14
ENSMUST00000176804.8
rho/rac guanine nucleotide exchange factor (GEF) 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
12.4 37.2 GO:0071846 actin filament debranching(GO:0071846)
11.4 34.1 GO:0014805 smooth muscle adaptation(GO:0014805)
10.3 92.4 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
8.5 67.7 GO:0061502 uropod organization(GO:0032796) early endosome to recycling endosome transport(GO:0061502)
8.0 63.9 GO:0033277 abortive mitotic cell cycle(GO:0033277)
6.5 13.0 GO:1902226 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
6.0 18.0 GO:0010925 regulation of inositol-polyphosphate 5-phosphatase activity(GO:0010924) positive regulation of inositol-polyphosphate 5-phosphatase activity(GO:0010925) phospholipase C-inhibiting G-protein coupled receptor signaling pathway(GO:0030845) regulation of cell diameter(GO:0060305)
5.5 33.1 GO:0006742 NADP catabolic process(GO:0006742)
5.5 21.9 GO:0035962 TRIF-dependent toll-like receptor signaling pathway(GO:0035666) interleukin-4-mediated signaling pathway(GO:0035771) response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963) negative regulation of apoptotic cell clearance(GO:2000426)
5.5 16.4 GO:0032685 negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685)
5.3 15.9 GO:0045404 interleukin-10 biosynthetic process(GO:0042091) interleukin-13 biosynthetic process(GO:0042231) regulation of interleukin-10 biosynthetic process(GO:0045074) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
4.9 29.7 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
4.9 14.7 GO:0002337 B-1a B cell differentiation(GO:0002337)
4.6 13.9 GO:0060559 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
4.6 13.7 GO:0010387 COP9 signalosome assembly(GO:0010387)
4.4 48.8 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
4.4 26.1 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
4.3 8.7 GO:0002649 regulation of tolerance induction to self antigen(GO:0002649)
4.2 12.7 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904)
4.1 12.4 GO:0090673 endothelial cell-matrix adhesion(GO:0090673)
3.7 18.7 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
3.7 11.2 GO:0006393 termination of mitochondrial transcription(GO:0006393)
3.7 3.7 GO:0032701 negative regulation of interleukin-18 production(GO:0032701)
3.7 18.4 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
3.6 10.7 GO:0002149 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
3.5 10.6 GO:0034240 negative regulation of macrophage fusion(GO:0034240)
3.5 14.0 GO:0070358 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) actin polymerization-dependent cell motility(GO:0070358)
3.3 10.0 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
3.0 14.8 GO:0070829 heterochromatin maintenance(GO:0070829)
2.9 5.8 GO:0032661 regulation of interleukin-18 production(GO:0032661)
2.8 19.8 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
2.7 8.1 GO:0070476 rRNA (guanine-N7)-methylation(GO:0070476)
2.7 10.7 GO:2000449 regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449)
2.7 8.0 GO:0002314 germinal center B cell differentiation(GO:0002314)
2.5 10.1 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
2.5 12.6 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
2.5 9.9 GO:0045659 negative regulation of neutrophil differentiation(GO:0045659)
2.3 6.8 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
2.2 6.7 GO:0002434 immune complex clearance(GO:0002434)
2.2 6.6 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
2.1 8.5 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
2.1 4.1 GO:0072717 cellular response to actinomycin D(GO:0072717)
2.0 24.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
2.0 9.9 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
1.9 9.3 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
1.9 5.6 GO:0034769 basement membrane disassembly(GO:0034769)
1.8 14.6 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
1.8 10.9 GO:0070895 transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895)
1.7 5.1 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206) CMP metabolic process(GO:0046035)
1.7 5.1 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788)
1.7 16.7 GO:0051025 negative regulation of immunoglobulin secretion(GO:0051025)
1.6 19.8 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
1.6 10.9 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
1.5 4.6 GO:0014739 positive regulation of muscle hyperplasia(GO:0014739)
1.5 4.5 GO:0060010 Sertoli cell fate commitment(GO:0060010)
1.5 6.0 GO:0071348 cellular response to interleukin-11(GO:0071348)
1.4 4.3 GO:1903722 regulation of centriole elongation(GO:1903722)
1.4 2.9 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
1.4 2.8 GO:1902623 negative regulation of neutrophil migration(GO:1902623)
1.3 5.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
1.3 15.4 GO:0048245 eosinophil chemotaxis(GO:0048245)
1.3 15.3 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
1.3 10.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
1.2 4.9 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
1.2 45.1 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
1.2 6.0 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
1.2 6.0 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
1.2 13.1 GO:0001955 blood vessel maturation(GO:0001955)
1.2 5.9 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
1.2 2.4 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
1.1 3.2 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
1.0 9.3 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
1.0 4.0 GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
1.0 7.9 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.9 6.6 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.9 33.2 GO:0045730 respiratory burst(GO:0045730)
0.9 17.0 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.9 4.7 GO:0042631 cellular response to water deprivation(GO:0042631)
0.9 2.7 GO:2000554 regulation of T-helper 1 cell cytokine production(GO:2000554) positive regulation of T-helper 1 cell cytokine production(GO:2000556)
0.9 2.7 GO:0035854 basophil differentiation(GO:0030221) eosinophil fate commitment(GO:0035854)
0.9 1.7 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.9 4.3 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.9 3.4 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.8 4.2 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.8 15.2 GO:0015816 glycine transport(GO:0015816)
0.8 11.8 GO:0045651 positive regulation of granulocyte differentiation(GO:0030854) positive regulation of macrophage differentiation(GO:0045651)
0.8 5.6 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.8 2.4 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.8 2.4 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.8 16.5 GO:0030574 collagen catabolic process(GO:0030574)
0.8 12.4 GO:0001771 immunological synapse formation(GO:0001771)
0.7 8.0 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.7 2.9 GO:0090400 stress-induced premature senescence(GO:0090400)
0.7 24.6 GO:0006270 DNA replication initiation(GO:0006270)
0.7 5.6 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.7 4.9 GO:0015867 ATP transport(GO:0015867)
0.7 3.5 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.7 18.5 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.7 11.5 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.7 18.9 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.6 19.3 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.6 17.9 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.6 2.4 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.6 9.1 GO:0032494 response to peptidoglycan(GO:0032494)
0.6 5.3 GO:0030321 transepithelial chloride transport(GO:0030321)
0.6 22.4 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.6 3.5 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.6 24.9 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.6 19.9 GO:0050832 defense response to fungus(GO:0050832)
0.6 4.5 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.6 3.9 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.5 6.5 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118)
0.5 4.1 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.5 2.0 GO:0002266 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.5 7.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.5 1.9 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.5 15.3 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.4 17.8 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.4 3.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.4 3.0 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.4 14.7 GO:0008053 mitochondrial fusion(GO:0008053)
0.4 3.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.4 2.4 GO:1900157 regulation of bone mineralization involved in bone maturation(GO:1900157)
0.4 2.8 GO:0051013 microtubule severing(GO:0051013)
0.4 2.7 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.4 3.5 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.4 1.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.4 6.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.4 0.4 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.4 1.5 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.4 8.4 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.4 1.4 GO:1904417 regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
0.3 2.8 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.3 4.7 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.3 1.7 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.3 2.0 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.3 0.3 GO:0034136 negative regulation of toll-like receptor 2 signaling pathway(GO:0034136)
0.3 4.9 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.3 14.0 GO:0043029 T cell homeostasis(GO:0043029)
0.3 6.0 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.3 4.6 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.3 13.2 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.3 4.0 GO:0051014 actin filament severing(GO:0051014)
0.3 6.6 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.3 6.0 GO:0035493 SNARE complex assembly(GO:0035493)
0.3 13.6 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.3 6.6 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.3 3.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.3 2.7 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.3 4.8 GO:0090161 Golgi ribbon formation(GO:0090161)
0.3 2.4 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.3 1.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 3.0 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.2 1.6 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.2 5.2 GO:0006491 N-glycan processing(GO:0006491)
0.2 8.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.2 1.2 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.2 3.5 GO:0001522 pseudouridine synthesis(GO:0001522)
0.2 4.4 GO:0046597 negative regulation of viral entry into host cell(GO:0046597) negative regulation of viral release from host cell(GO:1902187)
0.2 4.8 GO:0006910 phagocytosis, recognition(GO:0006910)
0.2 4.4 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.2 11.2 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.2 1.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.2 1.4 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.2 0.5 GO:0046038 GMP catabolic process(GO:0046038)
0.2 1.8 GO:0046606 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.2 36.1 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.2 5.2 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.2 23.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 13.1 GO:0043507 positive regulation of JUN kinase activity(GO:0043507)
0.1 10.1 GO:0045576 mast cell activation(GO:0045576)
0.1 1.4 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.1 3.3 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 24.6 GO:0002377 immunoglobulin production(GO:0002377)
0.1 6.8 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 20.3 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1 2.7 GO:0003283 atrial septum development(GO:0003283)
0.1 3.6 GO:0030033 microvillus assembly(GO:0030033)
0.1 26.1 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.1 3.9 GO:0034508 centromere complex assembly(GO:0034508)
0.1 2.8 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.1 11.1 GO:0046847 filopodium assembly(GO:0046847)
0.1 2.7 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.1 1.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.6 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.6 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.1 1.4 GO:0035330 regulation of hippo signaling(GO:0035330)
0.1 9.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 18.9 GO:0051607 defense response to virus(GO:0051607)
0.1 0.7 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.1 0.9 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.1 11.0 GO:0042113 B cell activation(GO:0042113)
0.1 1.3 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.1 10.2 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.1 0.8 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 4.7 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.1 1.6 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 4.6 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
0.1 1.0 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 4.2 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 3.3 GO:0046039 dopamine receptor signaling pathway(GO:0007212) GTP metabolic process(GO:0046039)
0.1 7.7 GO:0000956 nuclear-transcribed mRNA catabolic process(GO:0000956)
0.1 2.5 GO:0031648 protein destabilization(GO:0031648)
0.1 0.4 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.1 1.6 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
0.1 2.9 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 2.0 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 4.5 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 9.9 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 7.1 GO:0001843 neural tube closure(GO:0001843)
0.0 1.0 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 12.9 GO:0006869 lipid transport(GO:0006869)
0.0 6.9 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 3.7 GO:0070374 positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.0 3.2 GO:0032496 response to lipopolysaccharide(GO:0032496)
0.0 9.0 GO:0006936 muscle contraction(GO:0006936)
0.0 0.3 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 2.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.1 GO:0045761 regulation of adenylate cyclase activity(GO:0045761)
0.0 0.1 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.4 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 1.0 GO:0046425 regulation of JAK-STAT cascade(GO:0046425) regulation of STAT cascade(GO:1904892)
0.0 1.8 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.3 100.4 GO:0043020 NADPH oxidase complex(GO:0043020)
5.6 28.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
5.3 63.9 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
3.2 12.7 GO:0060171 stereocilium membrane(GO:0060171)
3.1 15.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
2.6 67.7 GO:0032426 stereocilium tip(GO:0032426)
1.9 13.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
1.8 22.8 GO:0005818 aster(GO:0005818)
1.7 27.6 GO:0042555 MCM complex(GO:0042555)
1.6 93.3 GO:0001772 immunological synapse(GO:0001772)
1.4 12.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
1.3 18.8 GO:0031209 SCAR complex(GO:0031209)
1.1 15.9 GO:0000788 nuclear nucleosome(GO:0000788)
1.1 10.7 GO:0097342 ripoptosome(GO:0097342)
1.0 12.6 GO:0008278 cohesin complex(GO:0008278)
1.0 5.2 GO:0017177 glucosidase II complex(GO:0017177)
1.0 10.9 GO:0042101 T cell receptor complex(GO:0042101)
1.0 5.8 GO:0036019 endolysosome(GO:0036019)
1.0 2.9 GO:0032156 septin cytoskeleton(GO:0032156)
1.0 2.9 GO:0055087 Ski complex(GO:0055087)
0.9 13.7 GO:0008180 COP9 signalosome(GO:0008180)
0.9 20.2 GO:0042627 chylomicron(GO:0042627)
0.9 3.5 GO:0032021 NELF complex(GO:0032021)
0.9 7.7 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.8 8.5 GO:1990462 omegasome(GO:1990462)
0.7 11.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.7 3.6 GO:0070820 tertiary granule(GO:0070820)
0.7 9.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.7 4.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.7 10.7 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.6 5.8 GO:0042581 specific granule(GO:0042581)
0.5 8.8 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.5 21.3 GO:0051233 spindle midzone(GO:0051233)
0.5 3.4 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.5 6.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.5 15.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.5 4.6 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.5 11.4 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.5 28.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.4 17.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.4 8.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.4 2.0 GO:1990130 Iml1 complex(GO:1990130)
0.4 2.0 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.4 16.7 GO:0008305 integrin complex(GO:0008305)
0.4 3.7 GO:0005642 annulate lamellae(GO:0005642)
0.4 4.4 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.4 1.4 GO:0097543 ciliary inversin compartment(GO:0097543)
0.3 4.3 GO:0090543 Flemming body(GO:0090543)
0.3 3.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.3 10.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.3 20.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 28.2 GO:0032587 ruffle membrane(GO:0032587)
0.2 6.9 GO:0042588 zymogen granule(GO:0042588)
0.2 2.2 GO:0000815 ESCRT III complex(GO:0000815)
0.2 3.7 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 21.4 GO:0005581 collagen trimer(GO:0005581)
0.2 12.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 2.3 GO:0030897 HOPS complex(GO:0030897)
0.2 0.5 GO:1902560 GMP reductase complex(GO:1902560)
0.2 2.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.2 1.0 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 4.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2 2.5 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.2 1.7 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.2 14.1 GO:0001726 ruffle(GO:0001726)
0.1 4.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 12.1 GO:0072686 mitotic spindle(GO:0072686)
0.1 0.4 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 4.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 17.3 GO:0030175 filopodium(GO:0030175)
0.1 6.1 GO:0035861 site of double-strand break(GO:0035861)
0.1 0.6 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 4.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 1.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 1.3 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 12.0 GO:0005795 Golgi stack(GO:0005795)
0.1 4.6 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 1.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 5.0 GO:0031252 cell leading edge(GO:0031252)
0.1 21.3 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 19.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 4.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 59.7 GO:0000323 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1 49.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 6.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 11.0 GO:0030863 cortical cytoskeleton(GO:0030863)
0.1 3.9 GO:0097440 apical dendrite(GO:0097440)
0.1 24.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 33.9 GO:0009986 cell surface(GO:0009986)
0.1 0.6 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 21.9 GO:0031965 nuclear membrane(GO:0031965)
0.1 0.7 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.8 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 2.8 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.5 GO:0060170 ciliary membrane(GO:0060170)
0.1 5.6 GO:0016363 nuclear matrix(GO:0016363)
0.1 87.0 GO:0005615 extracellular space(GO:0005615)
0.0 2.3 GO:0005776 autophagosome(GO:0005776)
0.0 61.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 3.6 GO:0030139 endocytic vesicle(GO:0030139)
0.0 1.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.4 GO:0097450 astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451)
0.0 2.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.2 GO:0005903 brush border(GO:0005903)
0.0 2.6 GO:0005811 lipid particle(GO:0005811)
0.0 1.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 3.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 10.8 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 2.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 12.5 GO:0005911 cell-cell junction(GO:0005911)
0.0 92.7 GO:0005886 plasma membrane(GO:0005886)
0.0 3.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.3 GO:0034709 methylosome(GO:0034709)
0.0 1.9 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.4 GO:0016235 aggresome(GO:0016235)
0.0 53.0 GO:0005829 cytosol(GO:0005829)
0.0 0.4 GO:0030686 90S preribosome(GO:0030686)
0.0 2.1 GO:0000794 condensed nuclear chromosome(GO:0000794)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
10.3 92.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
5.9 29.7 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
5.5 21.9 GO:0005136 interleukin-4 receptor binding(GO:0005136)
5.1 66.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
4.9 63.9 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
4.3 13.0 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
3.2 67.7 GO:0032036 myosin heavy chain binding(GO:0032036)
3.1 34.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
2.9 8.7 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
2.8 19.8 GO:0001851 complement component C3b binding(GO:0001851)
2.7 10.9 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
2.7 37.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
2.5 22.8 GO:0061676 importin-alpha family protein binding(GO:0061676)
2.5 20.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
2.5 10.0 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
2.2 8.9 GO:0004566 beta-glucuronidase activity(GO:0004566)
2.0 8.0 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
2.0 5.9 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
1.9 7.7 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
1.7 11.8 GO:0019770 IgG receptor activity(GO:0019770)
1.6 4.9 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
1.5 4.6 GO:0035375 zymogen binding(GO:0035375)
1.5 30.7 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
1.5 10.7 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
1.5 37.9 GO:0051400 BH domain binding(GO:0051400)
1.4 9.8 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
1.4 22.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
1.4 9.5 GO:0004920 interleukin-10 receptor activity(GO:0004920)
1.4 13.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
1.3 5.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
1.2 9.9 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312) PTB domain binding(GO:0051425)
1.2 4.9 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
1.2 14.6 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
1.2 28.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
1.1 3.4 GO:0003896 DNA primase activity(GO:0003896)
1.1 6.6 GO:0042289 MHC class II protein binding(GO:0042289)
1.1 15.4 GO:0019957 C-C chemokine binding(GO:0019957)
1.1 15.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
1.0 15.6 GO:0005522 profilin binding(GO:0005522)
0.9 17.0 GO:0003796 lysozyme activity(GO:0003796)
0.9 6.5 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.9 2.8 GO:0001847 opsonin receptor activity(GO:0001847)
0.9 10.6 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.8 10.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.8 4.5 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.7 10.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.7 5.1 GO:0004849 uridine kinase activity(GO:0004849)
0.7 4.3 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.7 6.1 GO:0000150 recombinase activity(GO:0000150)
0.7 48.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.7 25.4 GO:0004623 phospholipase A2 activity(GO:0004623)
0.6 8.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.6 5.7 GO:0016936 galactoside binding(GO:0016936)
0.6 3.7 GO:0042834 peptidoglycan binding(GO:0042834)
0.6 4.5 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.6 14.0 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.6 2.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.5 5.3 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
0.5 15.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.5 2.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.4 7.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.4 18.3 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.4 4.1 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.4 18.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.4 3.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.4 1.6 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.4 7.0 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.4 8.5 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.3 2.4 GO:0001179 RNA polymerase I transcription factor binding(GO:0001179)
0.3 1.0 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.3 20.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 11.2 GO:0001968 fibronectin binding(GO:0001968)
0.3 4.7 GO:0030274 LIM domain binding(GO:0030274)
0.3 1.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.3 3.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.3 1.7 GO:0089720 caspase binding(GO:0089720)
0.3 5.6 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.3 11.5 GO:0003785 actin monomer binding(GO:0003785)
0.3 16.7 GO:0070063 RNA polymerase binding(GO:0070063)
0.3 3.3 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.3 1.3 GO:0030621 U4 snRNA binding(GO:0030621)
0.2 10.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 9.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 16.6 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.2 1.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.2 8.1 GO:0008276 protein methyltransferase activity(GO:0008276)
0.2 2.4 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.2 31.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 4.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.2 2.9 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 79.8 GO:0005525 GTP binding(GO:0005525)
0.2 15.7 GO:0030295 protein kinase activator activity(GO:0030295)
0.2 61.2 GO:0030246 carbohydrate binding(GO:0030246)
0.2 7.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.2 0.5 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.2 9.3 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.2 12.1 GO:0019843 rRNA binding(GO:0019843)
0.2 33.2 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.2 6.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 2.7 GO:0035613 RNA stem-loop binding(GO:0035613)
0.2 2.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 6.0 GO:0017091 AU-rich element binding(GO:0017091)
0.1 2.7 GO:0070742 DNA binding, bending(GO:0008301) C2H2 zinc finger domain binding(GO:0070742)
0.1 6.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 8.0 GO:0008186 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 13.8 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 0.4 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 31.8 GO:0051015 actin filament binding(GO:0051015)
0.1 6.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 9.3 GO:0004386 helicase activity(GO:0004386)
0.1 0.7 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.1 25.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 2.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 2.3 GO:0050811 GABA receptor binding(GO:0050811)
0.1 31.3 GO:0005096 GTPase activator activity(GO:0005096)
0.1 2.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 1.4 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 1.0 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 15.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 3.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 11.2 GO:0003690 double-stranded DNA binding(GO:0003690)
0.1 6.7 GO:0051219 phosphoprotein binding(GO:0051219)
0.1 10.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.9 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 1.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 17.3 GO:0005125 cytokine activity(GO:0005125)
0.1 1.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 1.1 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 9.0 GO:0020037 heme binding(GO:0020037)
0.1 3.9 GO:0019894 kinesin binding(GO:0019894)
0.1 1.8 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 1.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.7 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.2 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 8.9 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 25.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.0 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 1.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 22.9 GO:0003682 chromatin binding(GO:0003682)
0.0 6.8 GO:0000287 magnesium ion binding(GO:0000287)
0.0 18.9 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 2.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 3.7 GO:0005178 integrin binding(GO:0005178)
0.0 33.3 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 7.7 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 10.3 GO:0003677 DNA binding(GO:0003677)
0.0 0.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 2.7 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 1.0 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 26.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
1.3 94.5 PID EPO PATHWAY EPO signaling pathway
1.2 36.9 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
1.0 13.9 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
1.0 80.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.9 89.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.9 47.4 PID ATR PATHWAY ATR signaling pathway
0.8 28.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.6 27.0 PID IL1 PATHWAY IL1-mediated signaling events
0.6 27.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.6 18.5 PID FANCONI PATHWAY Fanconi anemia pathway
0.6 18.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.6 25.9 PID BCR 5PATHWAY BCR signaling pathway
0.5 6.5 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.4 17.1 PID AURORA A PATHWAY Aurora A signaling
0.4 7.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.4 20.1 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.4 20.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.3 10.7 PID IL23 PATHWAY IL23-mediated signaling events
0.3 9.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.3 19.5 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.3 6.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.3 6.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.3 11.3 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.3 15.9 PID IL4 2PATHWAY IL4-mediated signaling events
0.3 7.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.3 2.8 PID IL27 PATHWAY IL27-mediated signaling events
0.3 18.5 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.3 4.9 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.2 12.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.2 4.9 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.2 7.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.2 4.8 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.2 34.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 4.3 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 13.4 PID CMYB PATHWAY C-MYB transcription factor network
0.1 8.7 PID E2F PATHWAY E2F transcription factor network
0.1 4.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 0.9 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 15.5 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 4.2 PID P53 REGULATION PATHWAY p53 pathway
0.1 1.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.8 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.1 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 5.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 74.5 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
2.7 21.5 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
1.9 5.6 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
1.7 27.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
1.7 30.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
1.5 74.0 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
1.4 25.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
1.3 22.8 REACTOME POL SWITCHING Genes involved in Polymerase switching
1.0 15.3 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
1.0 14.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
1.0 12.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.9 28.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.9 2.7 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.9 55.6 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.8 15.6 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.8 16.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.8 10.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.7 8.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.7 36.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.7 18.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.6 143.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.6 12.7 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.6 4.5 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.6 19.2 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.5 31.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.5 5.9 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.5 11.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.5 8.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.5 15.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.5 8.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.4 6.1 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.4 26.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.4 21.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.4 11.7 REACTOME KINESINS Genes involved in Kinesins
0.3 5.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.3 6.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.3 4.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.3 10.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.3 3.1 REACTOME DEADENYLATION DEPENDENT MRNA DECAY Genes involved in Deadenylation-dependent mRNA decay
0.3 20.0 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.3 9.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.3 11.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.3 30.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 6.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.2 16.7 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 4.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.2 22.2 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.2 3.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 10.1 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.2 13.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 38.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.2 3.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2 6.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 6.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 2.4 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.1 5.1 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 11.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 16.8 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.1 1.1 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1 3.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 4.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 5.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 2.2 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 3.0 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase