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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Srf

Z-value: 2.68

Motif logo

Transcription factors associated with Srf

Gene Symbol Gene ID Gene Info
ENSMUSG00000015605.7 Srf

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Srfmm39_v1_chr17_-_46867083_468671140.441.1e-04Click!

Activity profile of Srf motif

Sorted Z-values of Srf motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Srf

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_-_113883285 33.09 ENSMUST00000090269.7
actin, alpha, cardiac muscle 1
chr6_-_83513222 32.19 ENSMUST00000075161.12
actin, gamma 2, smooth muscle, enteric
chr6_-_83513184 27.92 ENSMUST00000205926.2
actin, gamma 2, smooth muscle, enteric
chr9_+_110592709 26.85 ENSMUST00000079784.12
myosin, light polypeptide 3
chr12_-_103322226 25.74 ENSMUST00000021617.14
ankyrin repeat and SOCS box-containing 2
chrX_+_100492684 25.23 ENSMUST00000033674.6
integrin beta 1 binding protein 2
chr10_+_45211847 20.71 ENSMUST00000095715.5
blood vessel epicardial substance
chr8_-_124621483 20.69 ENSMUST00000034453.6
ENSMUST00000212584.2
actin, alpha 1, skeletal muscle
chr1_-_43203051 19.56 ENSMUST00000008280.14
four and a half LIM domains 2
chr7_+_19144950 19.34 ENSMUST00000208710.2
ENSMUST00000003643.3
creatine kinase, muscle
chr10_+_32959472 18.96 ENSMUST00000095762.5
ENSMUST00000218281.2
ENSMUST00000217779.2
ENSMUST00000219665.2
ENSMUST00000219931.2
triadin
chr4_+_148085179 18.42 ENSMUST00000103230.5
natriuretic peptide type A
chr8_+_15107646 17.65 ENSMUST00000033842.4
myomesin 2
chr11_-_5848771 17.54 ENSMUST00000102921.4
myosin, light polypeptide 7, regulatory
chr14_-_34310602 17.24 ENSMUST00000064098.14
ENSMUST00000090040.12
ENSMUST00000022330.9
ENSMUST00000022327.13
LIM domain binding 3
chr14_-_55204054 15.94 ENSMUST00000226297.2
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr14_-_55204092 15.78 ENSMUST00000081857.14
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr2_+_156617329 15.77 ENSMUST00000088552.7
myosin, light polypeptide 9, regulatory
chr6_+_17306334 15.72 ENSMUST00000007799.13
ENSMUST00000115456.6
caveolin 1, caveolae protein
chr14_-_34310637 15.06 ENSMUST00000227819.2
LIM domain binding 3
chr3_+_106020545 14.71 ENSMUST00000079132.12
ENSMUST00000139086.2
chitinase, acidic 1
chr10_-_120735000 14.62 ENSMUST00000092143.12
methionine sulfoxide reductase B3
chr6_-_71239216 13.80 ENSMUST00000129630.3
ENSMUST00000114186.9
ENSMUST00000074301.10
SET and MYND domain containing 1
chr8_+_55003359 13.45 ENSMUST00000033918.4
ankyrin repeat and SOCs box-containing 5
chr14_-_34310438 13.37 ENSMUST00000228044.2
ENSMUST00000022328.14
LIM domain binding 3
chr11_+_82802079 12.79 ENSMUST00000018989.14
ENSMUST00000164945.3
unc-45 myosin chaperone B
chr5_-_113044216 11.40 ENSMUST00000086617.11
myosin XVIIIb
chr14_-_55204383 11.14 ENSMUST00000111456.2
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr4_-_141327146 10.68 ENSMUST00000141518.8
ENSMUST00000127455.8
ENSMUST00000105784.8
filamin binding LIM protein 1
chr1_-_43235914 10.59 ENSMUST00000187357.2
four and a half LIM domains 2
chr14_-_55204023 10.26 ENSMUST00000124930.8
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr6_+_87350292 10.23 ENSMUST00000032128.6
gastrokine 2
chr2_-_60503998 9.92 ENSMUST00000059888.15
ENSMUST00000154764.2
integrin beta 6
chr12_+_108389075 9.82 ENSMUST00000109860.8
echinoderm microtubule associated protein like 1
chr12_-_40249314 9.64 ENSMUST00000095760.3
leucine-rich single-pass membrane protein 1
chr9_-_58220469 9.41 ENSMUST00000061799.10
lysyl oxidase-like 1
chr11_-_120622770 9.24 ENSMUST00000154565.2
ENSMUST00000026148.9
carbonyl reductase 2
chr11_+_101221431 9.24 ENSMUST00000103105.10
amine oxidase, copper containing 3
chr16_-_10614679 9.22 ENSMUST00000023144.6
protamine 1
chr12_-_40249489 9.11 ENSMUST00000220951.2
leucine-rich single-pass membrane protein 1
chr7_-_142215027 8.05 ENSMUST00000105936.8
insulin-like growth factor 2
chr5_-_24534554 8.01 ENSMUST00000115098.7
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr1_-_33796790 7.75 ENSMUST00000187602.2
ENSMUST00000044691.9
BCL2-associated athanogene 2
chr7_+_3341597 7.62 ENSMUST00000164553.8
myeloid-associated differentiation marker
chr16_+_24266829 7.36 ENSMUST00000078988.10
LIM domain containing preferred translocation partner in lipoma
chr11_-_99383938 6.98 ENSMUST00000006969.8
keratin 23
chr4_-_141327253 6.93 ENSMUST00000147785.8
filamin binding LIM protein 1
chr2_+_150628655 6.89 ENSMUST00000045441.8
brain glycogen phosphorylase
chr4_+_43957401 6.72 ENSMUST00000030202.14
GLI pathogenesis-related 2
chr16_+_57369595 6.71 ENSMUST00000159414.2
filamin A interacting protein 1-like
chr7_+_127845984 6.68 ENSMUST00000164710.8
ENSMUST00000070656.12
transforming growth factor beta 1 induced transcript 1
chr7_+_127846121 6.67 ENSMUST00000167965.8
transforming growth factor beta 1 induced transcript 1
chr17_-_73706284 6.36 ENSMUST00000095208.4
calpain 13
chr3_+_68375495 6.31 ENSMUST00000182532.8
schwannomin interacting protein 1
chr14_-_45767421 6.14 ENSMUST00000150660.3
fermitin family member 2
chr11_+_33913013 5.88 ENSMUST00000020362.3
potassium large conductance calcium-activated channel, subfamily M, beta member 1
chr11_-_101315345 5.30 ENSMUST00000107257.8
ENSMUST00000107259.4
ENSMUST00000107252.9
ENSMUST00000093933.11
predicted gene, 27029
prostaglandin E synthase 3 like
chr2_-_18001734 5.24 ENSMUST00000105001.4
H2A histone family member L2A
chr4_+_19280850 5.03 ENSMUST00000102999.2
cyclic nucleotide gated channel beta 3
chr14_-_34224620 4.75 ENSMUST00000049005.15
bone morphogenetic protein receptor, type 1A
chr1_+_167445815 4.63 ENSMUST00000111380.2
retinoid X receptor gamma
chr4_+_43957677 4.56 ENSMUST00000107855.2
GLI pathogenesis-related 2
chr14_+_20979466 4.44 ENSMUST00000022369.9
vinculin
chr4_+_39450265 4.28 ENSMUST00000029955.5
RIKEN cDNA 1700009N14 gene
chr12_+_85520652 4.16 ENSMUST00000021674.7
FBJ osteosarcoma oncogene
chr17_-_46867083 4.05 ENSMUST00000015749.7
serum response factor
chr10_+_4216353 4.00 ENSMUST00000045730.7
A kinase (PRKA) anchor protein (gravin) 12
chr14_-_34224479 3.94 ENSMUST00000171551.2
bone morphogenetic protein receptor, type 1A
chr10_+_79824418 3.49 ENSMUST00000004784.11
ENSMUST00000105374.2
calponin 2
chr15_-_76113692 3.46 ENSMUST00000074834.12
plectin
chr17_+_5991555 3.38 ENSMUST00000115791.10
ENSMUST00000080283.13
synaptojanin 2
chr19_+_53517528 3.32 ENSMUST00000038287.7
dual specificity phosphatase 5
chr7_-_44646960 3.26 ENSMUST00000207443.2
ENSMUST00000207755.2
ENSMUST00000003290.12
BCL2-like 12 (proline rich)
chr15_+_102427149 3.23 ENSMUST00000146756.8
ENSMUST00000142194.3
TARBP2, RISC loading complex RNA binding subunit
chr1_+_39026887 3.14 ENSMUST00000194552.2
phosducin-like 3
chr14_-_45767575 3.06 ENSMUST00000045905.15
fermitin family member 2
chr2_+_20742115 3.05 ENSMUST00000114606.8
ENSMUST00000114608.3
enhancer trap locus 4
chr14_+_55813074 3.00 ENSMUST00000022826.7
fat storage-inducing transmembrane protein 1
chr5_-_100720063 2.96 ENSMUST00000031264.12
placenta-specific 8
chr1_+_74448535 2.90 ENSMUST00000027366.13
villin 1
chr3_-_57483330 2.87 ENSMUST00000120977.2
WW domain containing transcription regulator 1
chr11_-_120239301 2.83 ENSMUST00000062147.14
ENSMUST00000128055.2
actin, gamma, cytoplasmic 1
chr14_-_45767232 2.81 ENSMUST00000149723.2
fermitin family member 2
chr6_-_23248361 2.76 ENSMUST00000031709.7
Fez family zinc finger 1
chr7_-_142215595 2.66 ENSMUST00000145896.3
insulin-like growth factor 2
chr18_+_6603627 2.63 ENSMUST00000234821.2
ENSMUST00000044829.5
ENSMUST00000234337.2
RIKEN cDNA 4921524L21 gene
chr1_+_78794475 2.56 ENSMUST00000057262.8
ENSMUST00000187432.2
potassium voltage-gated channel, Isk-related subfamily, gene 4
chr15_+_84926909 2.54 ENSMUST00000229203.2
family with sequence similarity 118, member A
chr14_+_14901127 2.52 ENSMUST00000163790.2
predicted gene 3558
chr14_-_18054325 2.43 ENSMUST00000168866.2
predicted gene 3164
chr2_+_69210775 2.41 ENSMUST00000063690.4
dehydrogenase/reductase (SDR family) member 9
chr11_-_120238917 2.36 ENSMUST00000106215.11
actin, gamma, cytoplasmic 1
chr9_+_108313672 2.32 ENSMUST00000057265.8
cDNA sequence BC048562
chr2_-_164675357 2.30 ENSMUST00000042775.5
neuralized E3 ubiquitin protein ligase 2
chr2_+_154390808 2.30 ENSMUST00000045116.11
ENSMUST00000109709.4
RIKEN cDNA 1700003F12 gene
chr16_-_92262969 2.29 ENSMUST00000232239.2
ENSMUST00000060005.15
regulator of calcineurin 1
chr11_-_120239339 2.11 ENSMUST00000071555.13
actin, gamma, cytoplasmic 1
chr5_+_16139909 2.02 ENSMUST00000196750.2
calcium channel, voltage-dependent, alpha2/delta subunit 1
chr11_-_70560110 1.83 ENSMUST00000129434.2
ENSMUST00000018431.13
sperm associated antigen 7
chr17_-_46464441 1.80 ENSMUST00000171172.3
MAD2L1 binding protein
chr13_-_21722197 1.71 ENSMUST00000168629.2
ENSMUST00000218154.2
olfactory receptor 1366
chrX_+_11181397 1.68 ENSMUST00000179004.2
H2A histone family member L1F
chrX_+_11190898 1.68 ENSMUST00000164729.3
H2A histone family member L1I
chr14_+_16431564 1.67 ENSMUST00000164139.2
predicted gene 8206
chr14_-_16968099 1.64 ENSMUST00000181562.8
predicted gene, 3488
chr13_+_23930717 1.63 ENSMUST00000099703.5
H2B clustered histone 3
chr3_+_134918298 1.53 ENSMUST00000062893.12
centromere protein E
chr3_-_19365431 1.51 ENSMUST00000099195.10
phosphodiesterase 7A
chrX_+_11178173 1.49 ENSMUST00000178979.2
H2A histone family member L1E
chr14_-_17742998 1.42 ENSMUST00000165619.8
predicted gene 3252
chr13_-_103094784 1.42 ENSMUST00000172264.8
ENSMUST00000099202.10
microtubule associated serine/threonine kinase family member 4
chr13_+_52000704 1.41 ENSMUST00000021903.3
growth arrest and DNA-damage-inducible 45 gamma
chr15_-_99717956 1.40 ENSMUST00000109024.9
LIM domain and actin binding 1
chr6_-_113354826 1.34 ENSMUST00000032410.14
transcriptional adaptor 3
chr6_-_36787096 1.33 ENSMUST00000201321.2
ENSMUST00000101534.5
pleiotrophin
chr11_+_77353431 1.32 ENSMUST00000130255.2
coronin 6
chr7_+_119495058 1.25 ENSMUST00000106518.9
ENSMUST00000207270.2
ENSMUST00000208424.2
ENSMUST00000208202.2
ENSMUST00000054440.11
LYR motif containing 1
chr19_-_5962798 1.18 ENSMUST00000118623.2
D4, zinc and double PHD fingers family 2
chr14_+_15295240 1.16 ENSMUST00000172431.8
predicted gene 3512
chr14_-_17398733 1.16 ENSMUST00000163719.8
predicted gene, 8281
chr14_+_16361108 1.07 ENSMUST00000165193.2
predicted gene 3468
chr2_-_152256947 1.02 ENSMUST00000099207.5
zinc finger, CCHC domain containing 3
chr7_-_44646645 1.02 ENSMUST00000207342.2
BCL2-like 12 (proline rich)
chr6_-_113354668 0.99 ENSMUST00000193384.2
transcriptional adaptor 3
chr1_-_44118902 0.96 ENSMUST00000238662.2
predicted gene 8251
chr11_-_12362136 0.94 ENSMUST00000174874.8
cordon-bleu WH2 repeat
chr7_+_119495515 0.93 ENSMUST00000106517.9
LYR motif containing 1
chr2_-_111100733 0.93 ENSMUST00000099619.6
olfactory receptor 1277
chr14_-_17614197 0.88 ENSMUST00000166776.8
predicted gene 3264
chr19_-_5962862 0.87 ENSMUST00000136983.8
D4, zinc and double PHD fingers family 2
chrX_+_11187731 0.85 ENSMUST00000177926.3
H2A histone family member L1H
chr14_-_18817743 0.82 ENSMUST00000167430.8
predicted gene 3020
chr5_+_103902020 0.82 ENSMUST00000054979.10
AF4/FMR2 family, member 1
chr17_+_28259749 0.80 ENSMUST00000233869.2
ankyrin repeat and SAM domain containing 1
chr14_-_19420488 0.78 ENSMUST00000166494.2
predicted gene 2897
chr14_-_19137146 0.76 ENSMUST00000177786.8
predicted gene 2956
chr17_+_37756371 0.74 ENSMUST00000078207.4
ENSMUST00000218675.2
olfactory receptor 108
chrX_+_11175063 0.73 ENSMUST00000178595.2
H2A histone family member L1D
chr15_-_77129706 0.69 ENSMUST00000228361.2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr14_-_18359247 0.63 ENSMUST00000170207.8
predicted gene 8108
chrY_-_10147183 0.63 ENSMUST00000189630.2
predicted gene, 21310
chr14_-_19057159 0.62 ENSMUST00000170123.2
predicted gene 10409
chr14_+_16728196 0.58 ENSMUST00000177556.8
predicted gene 3373
chr14_+_15579811 0.53 ENSMUST00000171906.2
predicted gene 3667
chr14_+_15154724 0.53 ENSMUST00000165744.2
predicted gene 3739
chr14_-_19635203 0.53 ENSMUST00000170694.9
predicted gene 2237
chr7_+_17743802 0.52 ENSMUST00000081703.8
ENSMUST00000108488.7
carcinoembryonic antigen-related cell adhesion molecule 13
chr9_+_75213570 0.51 ENSMUST00000213990.2
guanine nucleotide binding protein (G protein), beta 5
chr9_+_72952115 0.51 ENSMUST00000184146.8
ENSMUST00000034722.5
RAB27A, member RAS oncogene family
chr13_+_109397184 0.39 ENSMUST00000153234.8
phosphodiesterase 4D, cAMP specific
chr7_-_119494918 0.37 ENSMUST00000059851.14
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr14_-_18287197 0.36 ENSMUST00000164512.8
predicted gene 2974
chr7_-_101859308 0.36 ENSMUST00000070165.7
ENSMUST00000211235.2
ENSMUST00000211022.2
nucleoporin 98
chr5_+_24618380 0.35 ENSMUST00000049346.10
acid-sensing (proton-gated) ion channel 3
chr16_-_4698148 0.35 ENSMUST00000037843.7
UBA-like domain containing 1
chr7_-_119494669 0.34 ENSMUST00000098080.9
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr3_-_93846078 0.34 ENSMUST00000177735.2
TD and POZ domain containing 9, pseudogene 1
chr14_+_16182428 0.28 ENSMUST00000170104.3
predicted gene 3411
chr5_-_148336574 0.27 ENSMUST00000202457.4
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr6_-_97156032 0.25 ENSMUST00000095664.6
TATA element modulatory factor 1
chr4_-_116228921 0.24 ENSMUST00000239239.2
ENSMUST00000239177.2
microtubule associated serine/threonine kinase 2
chr7_-_101859379 0.18 ENSMUST00000210682.2
nucleoporin 98
chr14_+_15442324 0.18 ENSMUST00000170738.3
predicted gene 10406
chr7_-_101859033 0.17 ENSMUST00000211005.2
nucleoporin 98
chr14_+_17080724 0.17 ENSMUST00000177986.8
predicted gene 3500
chr17_-_37508902 0.15 ENSMUST00000055324.8
olfactory receptor 94
chr15_-_77129786 0.15 ENSMUST00000228558.2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr19_+_12655487 0.13 ENSMUST00000215134.2
ENSMUST00000049724.8
olfactory receptor 1443
chr13_-_21823691 0.12 ENSMUST00000043081.3
olfactory receptor 11
chr4_-_43025792 0.05 ENSMUST00000067481.6
phosphatidylinositol glycan anchor biosynthesis, class O
chr8_+_95113066 0.02 ENSMUST00000161576.8
ENSMUST00000034220.8
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr14_-_18897750 0.02 ENSMUST00000178728.2
predicted gene 3005
chr4_-_43025756 0.01 ENSMUST00000098109.9
phosphatidylinositol glycan anchor biosynthesis, class O
chr2_+_143757193 0.01 ENSMUST00000103172.4
destrin

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
13.3 53.1 GO:0007522 visceral muscle development(GO:0007522)
7.5 30.2 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
4.9 53.8 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
4.6 18.4 GO:1902304 positive regulation of potassium ion export(GO:1902304)
4.1 20.7 GO:0060931 sinoatrial node cell development(GO:0060931)
3.7 14.6 GO:0030091 protein repair(GO:0030091)
3.2 19.0 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
2.9 8.7 GO:0021998 neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) positive regulation of cardiac ventricle development(GO:1904414)
2.6 15.7 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
2.0 8.0 GO:1902303 negative regulation of potassium ion export(GO:1902303)
2.0 5.9 GO:1903412 response to bile acid(GO:1903412) cellular response to bile acid(GO:1903413)
1.6 14.7 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
1.6 17.7 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
1.5 9.2 GO:0006116 NADH oxidation(GO:0006116)
1.4 4.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
1.3 13.4 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
1.1 9.9 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
1.0 7.6 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.9 10.7 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.9 17.6 GO:0033623 regulation of integrin activation(GO:0033623)
0.9 11.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.8 55.3 GO:0045214 sarcomere organization(GO:0045214)
0.7 2.9 GO:1902896 terminal web assembly(GO:1902896)
0.7 12.0 GO:0033622 integrin activation(GO:0033622)
0.7 6.1 GO:0035902 response to immobilization stress(GO:0035902)
0.6 26.9 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.5 3.2 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.5 2.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4 3.1 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.4 5.2 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.4 2.0 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.4 3.0 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.4 4.3 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.3 4.0 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.3 1.3 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.3 6.9 GO:0000272 polysaccharide catabolic process(GO:0000272)
0.3 2.9 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.3 4.2 GO:0035994 response to muscle stretch(GO:0035994)
0.3 11.5 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.3 25.7 GO:0045445 myoblast differentiation(GO:0045445)
0.3 2.4 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 19.3 GO:0042398 cellular modified amino acid biosynthetic process(GO:0042398)
0.2 6.3 GO:0001553 luteinization(GO:0001553)
0.2 3.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 4.4 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.2 4.3 GO:0000054 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
0.2 3.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 9.2 GO:0030261 chromosome condensation(GO:0030261)
0.2 0.8 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.2 1.5 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.2 11.3 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.2 0.5 GO:1903433 regulation of constitutive secretory pathway(GO:1903433)
0.2 3.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.2 0.9 GO:0001757 somite specification(GO:0001757)
0.1 3.5 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.1 4.6 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 13.9 GO:0070527 platelet aggregation(GO:0070527)
0.1 0.7 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 12.8 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.1 9.8 GO:0007405 neuroblast proliferation(GO:0007405)
0.1 3.0 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 1.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 1.1 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 1.8 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 2.3 GO:0007614 short-term memory(GO:0007614)
0.1 0.8 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.2 GO:2000845 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.1 0.4 GO:0050915 sensory perception of sour taste(GO:0050915) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.1 6.4 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.4 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0 0.5 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 4.7 GO:0007601 visual perception(GO:0007601)
0.0 0.2 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 1.4 GO:0031529 ruffle organization(GO:0031529)
0.0 0.6 GO:0051443 protein neddylation(GO:0045116) positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 3.1 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.3 GO:0015809 arginine transport(GO:0015809)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
11.0 33.1 GO:0042643 actomyosin, actin portion(GO:0042643)
4.7 19.0 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
3.7 25.7 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
2.6 70.8 GO:0005859 muscle myosin complex(GO:0005859)
2.0 9.9 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
1.7 18.4 GO:0042629 mast cell granule(GO:0042629)
1.6 8.0 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
1.1 74.5 GO:0031672 A band(GO:0031672)
0.9 15.7 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.9 13.9 GO:0016460 myosin II complex(GO:0016460)
0.8 4.2 GO:0035976 AP1 complex(GO:0035976)
0.7 11.4 GO:0016461 unconventional myosin complex(GO:0016461)
0.5 11.4 GO:1990023 mitotic spindle midzone(GO:1990023)
0.5 2.3 GO:0005927 muscle tendon junction(GO:0005927)
0.5 57.4 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.5 14.5 GO:0000786 nucleosome(GO:0000786)
0.4 7.3 GO:0043034 costamere(GO:0043034)
0.4 63.2 GO:0030018 Z disc(GO:0030018)
0.3 3.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068) RISC-loading complex(GO:0070578)
0.3 2.9 GO:0032432 actin filament bundle(GO:0032432)
0.3 3.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.3 20.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 2.0 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 0.9 GO:1990357 terminal web(GO:1990357)
0.1 13.7 GO:0045178 basal part of cell(GO:0045178)
0.1 0.7 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 28.3 GO:0072562 blood microparticle(GO:0072562)
0.1 10.7 GO:0005604 basement membrane(GO:0005604)
0.1 9.2 GO:0005902 microvillus(GO:0005902)
0.1 6.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 1.1 GO:0000124 SAGA complex(GO:0000124)
0.1 8.7 GO:0005901 caveola(GO:0005901)
0.1 7.0 GO:0005882 intermediate filament(GO:0005882)
0.1 6.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 24.1 GO:0005925 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.0 2.1 GO:0090544 BAF-type complex(GO:0090544)
0.0 5.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 4.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 11.3 GO:0000139 Golgi membrane(GO:0000139)
0.0 9.6 GO:0000790 nuclear chromatin(GO:0000790)
0.0 2.2 GO:0030496 midbody(GO:0030496)
0.0 0.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 6.9 GO:0030424 axon(GO:0030424)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.6 53.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
3.1 9.2 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
2.8 19.3 GO:0004111 creatine kinase activity(GO:0004111)
2.6 15.7 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
2.4 14.6 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
2.2 13.4 GO:0048495 Roundabout binding(GO:0048495)
2.1 63.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
1.7 6.9 GO:0008184 glycogen phosphorylase activity(GO:0008184)
1.6 14.7 GO:0004568 chitinase activity(GO:0004568)
1.3 8.0 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
1.3 9.2 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
1.0 15.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.9 8.7 GO:0098821 BMP receptor activity(GO:0098821)
0.8 5.0 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.8 17.6 GO:0031005 filamin binding(GO:0031005)
0.7 7.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.7 29.2 GO:0003785 actin monomer binding(GO:0003785)
0.7 2.0 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.6 18.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.5 4.6 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.4 9.4 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.4 20.7 GO:0030552 cAMP binding(GO:0030552)
0.4 33.6 GO:0017022 myosin binding(GO:0017022)
0.4 3.2 GO:0070883 pre-miRNA binding(GO:0070883)
0.4 2.4 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.4 2.9 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.3 3.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.3 1.3 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.3 10.7 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.3 4.1 GO:0070878 primary miRNA binding(GO:0070878)
0.3 4.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.3 3.4 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.3 2.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 12.8 GO:0051879 Hsp90 protein binding(GO:0051879)
0.2 1.5 GO:0043515 kinetochore binding(GO:0043515)
0.2 35.2 GO:0005178 integrin binding(GO:0005178)
0.2 6.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 11.9 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.2 12.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 4.2 GO:0070412 R-SMAD binding(GO:0070412)
0.1 4.0 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 3.5 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 25.7 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 4.3 GO:0002039 p53 binding(GO:0002039)
0.0 4.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 68.0 GO:0005524 ATP binding(GO:0005524)
0.0 0.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 1.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.3 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 8.4 GO:0008017 microtubule binding(GO:0008017)
0.0 0.6 GO:0097602 cullin family protein binding(GO:0097602)
0.0 4.7 GO:0044325 ion channel binding(GO:0044325)
0.0 0.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 4.3 GO:0042393 histone binding(GO:0042393)
0.0 0.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 38.2 GO:0042802 identical protein binding(GO:0042802)
0.0 11.5 GO:0005509 calcium ion binding(GO:0005509)
0.0 4.3 GO:0003924 GTPase activity(GO:0003924)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 2.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 67.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.8 30.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.6 33.3 PID RHOA PATHWAY RhoA signaling pathway
0.5 15.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.4 9.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 19.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.2 5.5 PID CONE PATHWAY Visual signal transduction: Cones
0.2 10.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 8.7 PID BMP PATHWAY BMP receptor signaling
0.1 8.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 4.6 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 10.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 6.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 3.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 1.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 2.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.5 PID PLK1 PATHWAY PLK1 signaling events
0.0 4.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 158.4 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
1.0 29.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.6 18.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.5 15.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.5 10.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.4 6.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.3 8.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.2 4.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 32.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.2 5.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 39.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 8.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 3.2 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 3.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 19.3 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 9.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 3.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 2.4 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events