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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Stat2

Z-value: 2.80

Motif logo

Transcription factors associated with Stat2

Gene Symbol Gene ID Gene Info
ENSMUSG00000040033.17 Stat2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Stat2mm39_v1_chr10_+_128106414_1281064460.747.1e-14Click!

Activity profile of Stat2 motif

Sorted Z-values of Stat2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Stat2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr14_+_78141679 30.97 ENSMUST00000022591.16
ENSMUST00000169978.2
ENSMUST00000227903.2
epithelial stromal interaction 1 (breast)
chr11_-_83421333 24.93 ENSMUST00000035938.3
chemokine (C-C motif) ligand 5
chr12_-_26506422 24.10 ENSMUST00000020970.10
radical S-adenosyl methionine domain containing 2
chrX_-_9335525 20.35 ENSMUST00000015484.10
cytochrome b-245, beta polypeptide
chr6_+_121222865 20.15 ENSMUST00000032198.11
ubiquitin specific peptidase 18
chr1_-_173318607 19.41 ENSMUST00000160565.4
interferon activated gene 206
chr7_-_104114384 18.95 ENSMUST00000076922.6
tripartite motif-containing 30A
chr1_-_173426640 18.60 ENSMUST00000150649.9
ENSMUST00000180215.2
ENSMUST00000097462.9
interferon activated gene 213
chr15_-_77417512 17.72 ENSMUST00000062562.7
ENSMUST00000230863.2
apolipoprotein L 7c
chr1_+_173501215 17.32 ENSMUST00000085876.12
interferon activated gene 208
chr4_-_156285247 17.28 ENSMUST00000085425.6
ISG15 ubiquitin-like modifier
chr2_-_173060647 17.27 ENSMUST00000109116.3
ENSMUST00000029018.14
Z-DNA binding protein 1
chr1_+_170846482 17.23 ENSMUST00000078825.5
Fc receptor, IgG, low affinity IV
chr1_-_173770010 17.16 ENSMUST00000042228.15
ENSMUST00000081216.12
ENSMUST00000129829.8
ENSMUST00000123708.8
interferon activated gene 203
chr7_+_142014546 16.91 ENSMUST00000105968.8
ENSMUST00000018963.11
ENSMUST00000105967.8
lymphocyte specific 1
chr1_-_85526517 16.88 ENSMUST00000093508.7
Sp110 nuclear body protein
chr7_-_104157006 16.75 ENSMUST00000033211.14
ENSMUST00000071069.13
tripartite motif-containing 30D
chr1_-_173707677 16.71 ENSMUST00000190651.4
ENSMUST00000188804.7
myeloid nuclear differentiation antigen like
chr4_-_46536088 16.69 ENSMUST00000102924.3
ENSMUST00000046897.13
tripartite motif-containing 14
chr17_+_34406523 16.66 ENSMUST00000170086.8
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr1_+_85577709 16.65 ENSMUST00000155094.8
ENSMUST00000054279.15
ENSMUST00000147552.8
ENSMUST00000153574.8
ENSMUST00000150967.8
nuclear antigen Sp100
chr17_-_34406193 16.63 ENSMUST00000173831.3
proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
chr1_+_85577766 16.61 ENSMUST00000066427.11
nuclear antigen Sp100
chr4_-_42773987 16.57 ENSMUST00000095114.5
chemokine (C-C motif) ligand 21A (serine)
chr9_+_107852733 16.41 ENSMUST00000035216.11
ubiquitin-like modifier activating enzyme 7
chr15_+_79776597 16.09 ENSMUST00000175714.8
ENSMUST00000109620.10
ENSMUST00000165537.8
ENSMUST00000175752.8
ENSMUST00000176325.8
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3
chr7_-_140590605 16.07 ENSMUST00000026565.7
interferon induced transmembrane protein 3
chr4_-_155013002 16.05 ENSMUST00000152687.8
ENSMUST00000137803.8
ENSMUST00000145296.2
tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
chr6_+_145067457 16.00 ENSMUST00000032396.13
lymphoid-restricted membrane protein
chr1_-_173859321 15.43 ENSMUST00000059226.7
interferon activated gene 205
chr19_+_34618271 15.33 ENSMUST00000102824.4
interferon-induced protein with tetratricopeptide repeats 1
chr11_+_46701619 15.29 ENSMUST00000068877.7
T cell immunoglobulin and mucin domain containing 4
chr7_-_140846328 15.17 ENSMUST00000106023.8
ENSMUST00000097952.9
ENSMUST00000026571.11
interferon regulatory factor 7
chr17_+_34406762 15.03 ENSMUST00000041633.15
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr13_+_120761861 14.88 ENSMUST00000225029.2
cDNA sequence BC147527
chr10_+_51367052 14.73 ENSMUST00000217705.2
ENSMUST00000078778.5
ENSMUST00000220182.2
ENSMUST00000220226.2
leukocyte immunoglobulin-like receptor, subfamily B, member 4A
chr1_-_173740467 14.40 ENSMUST00000009340.10
interferon activated gene 211
chr19_+_12438125 14.04 ENSMUST00000081035.9
macrophage expressed gene 1
chr6_+_39358036 14.02 ENSMUST00000031986.5
RAB19, member RAS oncogene family
chr4_-_42756489 13.97 ENSMUST00000140546.3
ENSMUST00000102957.6
chemokine (C-C motif) ligand 19
chr5_-_121045568 13.96 ENSMUST00000080322.8
2'-5' oligoadenylate synthetase 1A
chr1_+_175459559 13.93 ENSMUST00000040250.15
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr16_+_10306075 13.31 ENSMUST00000023147.8
class II transactivator
chr19_+_10819896 13.21 ENSMUST00000025646.3
solute carrier family 15, member 3
chr1_+_34511793 13.07 ENSMUST00000188972.3
protein tyrosine phosphatase, non-receptor type 18
chr1_-_173594475 12.98 ENSMUST00000111214.4
interferon activated gene 204
chr4_-_155012534 12.92 ENSMUST00000219534.3
tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
chr3_-_14843512 12.85 ENSMUST00000094365.11
carbonic anhydrase 1
chr7_+_78563184 12.83 ENSMUST00000121645.8
interferon-stimulated protein
chr11_-_78875689 12.83 ENSMUST00000108269.10
ENSMUST00000108268.10
lectin, galactose binding, soluble 9
chr6_+_41498716 12.50 ENSMUST00000070380.5
protease, serine 2
chr15_-_77527470 12.38 ENSMUST00000181154.2
ENSMUST00000180949.8
ENSMUST00000166623.10
apolipoprotein L 11b
chr11_+_88890202 12.37 ENSMUST00000100627.9
ENSMUST00000107896.10
ENSMUST00000000284.7
tripartite motif-containing 25
chr16_-_35691914 12.36 ENSMUST00000042665.9
poly (ADP-ribose) polymerase family, member 14
chr11_-_48870105 12.28 ENSMUST00000141200.2
ENSMUST00000097494.9
ENSMUST00000093153.2
RIKEN cDNA 9930111J21 gene 1
chr18_+_60515755 12.23 ENSMUST00000237185.2
interferon inducible GTPase 1
chr7_+_78563513 12.22 ENSMUST00000038142.15
interferon-stimulated protein
chr5_-_120915693 12.13 ENSMUST00000044833.9
2'-5' oligoadenylate synthetase 3
chr2_-_180883813 12.04 ENSMUST00000094203.11
ENSMUST00000108831.8
helicase with zinc finger 2, transcriptional coactivator
chr6_+_29529275 11.93 ENSMUST00000163511.7
interferon regulatory factor 5
chr7_-_140535899 11.92 ENSMUST00000081649.10
interferon induced transmembrane protein 2
chr1_-_173363523 11.86 ENSMUST00000139092.8
interferon activated gene 214
chr11_-_48941949 11.74 ENSMUST00000132768.2
ENSMUST00000101295.9
ENSMUST00000093152.2
RIKEN cDNA 9930111J21 gene 2
chr5_-_120887864 11.70 ENSMUST00000053909.13
ENSMUST00000081491.13
2'-5' oligoadenylate synthetase 2
chr13_+_37529184 11.70 ENSMUST00000021860.7
lymphocyte antigen 86
chr11_-_82911615 11.67 ENSMUST00000038141.15
ENSMUST00000092838.11
schlafen 8
chr1_+_175459735 11.66 ENSMUST00000097458.4
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr7_+_78563964 11.65 ENSMUST00000120331.4
interferon-stimulated protein
chr11_-_78875657 11.64 ENSMUST00000073001.5
lectin, galactose binding, soluble 9
chr16_+_35758836 11.62 ENSMUST00000114878.8
poly (ADP-ribose) polymerase family, member 9
chr7_+_43057611 11.56 ENSMUST00000005592.7
sialic acid binding Ig-like lectin G
chr8_-_71990085 11.37 ENSMUST00000051672.9
bone marrow stromal cell antigen 2
chr11_+_58090382 11.34 ENSMUST00000035266.11
ENSMUST00000094169.11
ENSMUST00000168280.2
ENSMUST00000058704.9
interferon gamma induced GTPase
immunity-related GTPase family M member 2
chr2_-_180883746 11.17 ENSMUST00000121484.2
helicase with zinc finger 2, transcriptional coactivator
chr4_-_155012643 10.88 ENSMUST00000123514.8
tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
chr7_+_103893658 10.81 ENSMUST00000106849.9
ENSMUST00000060315.12
tripartite motif-containing 34A
chr14_+_55842002 10.81 ENSMUST00000138037.2
interferon regulatory factor 9
chr18_+_60345152 10.78 ENSMUST00000031549.6
predicted gene 4951
chr17_-_35081129 10.61 ENSMUST00000154526.8
complement factor B
chr8_+_67947494 10.30 ENSMUST00000093470.7
ENSMUST00000163856.3
N-acetyltransferase 2 (arylamine N-acetyltransferase)
chr7_+_78564062 10.28 ENSMUST00000205981.2
interferon-stimulated protein
chr15_-_76127600 10.18 ENSMUST00000165738.8
ENSMUST00000075689.7
poly (ADP-ribose) polymerase family, member 10
chr6_+_128339882 10.17 ENSMUST00000073316.13
forkhead box M1
chr16_+_35759346 10.10 ENSMUST00000023622.13
poly (ADP-ribose) polymerase family, member 9
chr16_+_23428650 10.08 ENSMUST00000038423.6
ENSMUST00000211349.2
receptor transporter protein 4
chr11_-_82911548 9.85 ENSMUST00000108152.9
schlafen 8
chr7_+_44485704 9.81 ENSMUST00000033015.8
interleukin 4 induced 1
chr14_+_14475188 9.77 ENSMUST00000026315.8
deoxyribonuclease 1-like 3
chr11_+_106642052 9.72 ENSMUST00000147326.9
ENSMUST00000182896.8
ENSMUST00000182908.8
ENSMUST00000086353.11
mast cell immunoglobulin like receptor 1
chr8_+_72943455 9.52 ENSMUST00000072097.14
hematopoietic SH2 domain containing
chr7_-_140535828 9.48 ENSMUST00000211129.2
predicted gene 45717
chr7_+_103893672 9.42 ENSMUST00000106848.8
tripartite motif-containing 34A
chr8_-_112064783 9.38 ENSMUST00000056157.14
ENSMUST00000120432.3
mixed lineage kinase domain-like
chr10_+_87696339 9.38 ENSMUST00000121161.8
insulin-like growth factor 1
chr3_-_136031799 9.37 ENSMUST00000196159.5
ENSMUST00000041577.13
B cell scaffold protein with ankyrin repeats 1
chr9_-_58156982 9.37 ENSMUST00000135310.8
ENSMUST00000085673.11
ENSMUST00000114136.9
ENSMUST00000153820.8
ENSMUST00000124982.2
promyelocytic leukemia
chrX_+_84913911 9.34 ENSMUST00000113976.2
TLR adaptor interacting with endolysosomal SLC15A4
chr1_-_173569301 9.32 ENSMUST00000042610.15
ENSMUST00000127730.2
interferon activated gene 207
chr17_+_75772475 9.31 ENSMUST00000095204.6
RAS, guanyl releasing protein 3
chr16_-_10603389 9.21 ENSMUST00000229866.2
ENSMUST00000038099.6
suppressor of cytokine signaling 1
chr11_-_118292758 9.13 ENSMUST00000043722.10
lectin, galactoside-binding, soluble, 3 binding protein
chr11_-_100595019 9.08 ENSMUST00000017974.13
DEXH (Asp-Glu-X-His) box polypeptide 58
chr11_-_48883053 8.99 ENSMUST00000059930.3
ENSMUST00000068063.4
predicted gene 12185
T cell specific GTPase 1
chr5_-_121025645 8.77 ENSMUST00000086368.12
2'-5' oligoadenylate synthetase 1G
chr7_-_102214636 8.76 ENSMUST00000106913.3
ENSMUST00000033264.12
tripartite motif-containing 21
chr17_-_35392254 8.69 ENSMUST00000025257.12
allograft inflammatory factor 1
chr16_-_35759461 8.64 ENSMUST00000081933.14
ENSMUST00000114885.3
deltex 3-like, E3 ubiquitin ligase
chr13_+_74787952 8.64 ENSMUST00000221822.2
ENSMUST00000221526.2
endoplasmic reticulum aminopeptidase 1
chr18_-_78185334 8.61 ENSMUST00000160639.2
solute carrier family 14 (urea transporter), member 1
chr2_-_51862941 8.47 ENSMUST00000145481.8
ENSMUST00000112705.9
N-myc (and STAT) interactor
chr3_-_7678785 8.47 ENSMUST00000194279.6
interleukin 7
chr15_-_66684442 8.46 ENSMUST00000100572.10
src-like adaptor
chr10_-_43880353 8.19 ENSMUST00000020017.14
crystallin beta-gamma domain containing 1
chr11_-_118292678 8.14 ENSMUST00000106290.4
lectin, galactoside-binding, soluble, 3 binding protein
chr2_+_121978156 8.12 ENSMUST00000102476.5
beta-2 microglobulin
chr3_+_60408600 8.08 ENSMUST00000099087.8
muscleblind like splicing factor 1
chr1_+_171216480 8.04 ENSMUST00000056449.9
Rho GTPase activating protein 30
chr13_-_100338469 8.01 ENSMUST00000167986.3
ENSMUST00000117913.8
NLR family, apoptosis inhibitory protein 2
chr3_-_7678796 8.00 ENSMUST00000192202.6
interleukin 7
chr6_-_38331187 7.77 ENSMUST00000114900.8
ENSMUST00000143702.5
zinc finger CCCH type, antiviral 1
chr9_-_58156935 7.52 ENSMUST00000124063.2
ENSMUST00000126690.8
promyelocytic leukemia
chr14_+_55815999 7.45 ENSMUST00000172738.2
ENSMUST00000089619.13
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr19_+_34560922 7.43 ENSMUST00000102825.4
interferon-induced protein with tetratricopeptide repeats 3
chr11_+_106642079 7.40 ENSMUST00000183111.8
ENSMUST00000106794.9
mast cell immunoglobulin like receptor 1
chr11_-_70350783 7.39 ENSMUST00000019064.9
chemokine (C-X-C motif) ligand 16
chr3_-_151455514 7.38 ENSMUST00000029671.9
interferon-induced protein 44
chr5_-_92496730 7.33 ENSMUST00000038816.13
ENSMUST00000118006.3
chemokine (C-X-C motif) ligand 10
chr10_+_87695886 7.24 ENSMUST00000062862.13
insulin-like growth factor 1
chr15_+_77613239 7.23 ENSMUST00000230979.2
ENSMUST00000109775.4
apolipoprotein L 9b
chr11_-_82882613 7.13 ENSMUST00000092840.11
ENSMUST00000038211.13
schlafen 9
chr10_-_94780695 7.10 ENSMUST00000099337.5
plexin C1
chr19_+_6214416 7.07 ENSMUST00000045042.8
ENSMUST00000237511.2
basic leucine zipper transcription factor, ATF-like 2
chr17_-_35081456 6.86 ENSMUST00000025229.11
ENSMUST00000176203.9
ENSMUST00000128767.8
complement factor B
chr13_-_56326695 6.85 ENSMUST00000225063.2
TRAF-interacting protein with forkhead-associated domain, family member B
chr5_-_137145030 6.84 ENSMUST00000054384.6
ENSMUST00000152207.2
tripartite motif-containing 56
chr9_+_118307412 6.83 ENSMUST00000035020.15
eomesodermin
chr14_+_55815879 6.78 ENSMUST00000174563.8
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr13_-_56326511 6.76 ENSMUST00000169652.3
TRAF-interacting protein with forkhead-associated domain, family member B
chrX_+_41239872 6.75 ENSMUST00000123245.8
stromal antigen 2
chr3_+_60408678 6.75 ENSMUST00000191747.6
ENSMUST00000194069.6
muscleblind like splicing factor 1
chr7_-_101667346 6.65 ENSMUST00000209844.2
ENSMUST00000211502.2
ENSMUST00000094134.5
interleukin 18 binding protein
chr17_+_34354556 6.62 ENSMUST00000236322.2
ENSMUST00000237402.2
histocompatibility 2, class II, locus DMa
chr3_-_136031723 6.61 ENSMUST00000198206.2
B cell scaffold protein with ankyrin repeats 1
chr9_-_106353571 6.61 ENSMUST00000123555.8
ENSMUST00000125850.2
poly (ADP-ribose) polymerase family, member 3
chr11_-_48762170 6.59 ENSMUST00000049519.4
ENSMUST00000097271.4
immunity-related GTPase family M member 1
chr1_+_85454323 6.58 ENSMUST00000239236.2
predicted gene 7592
chr14_+_54429757 6.43 ENSMUST00000103714.2
T cell receptor alpha joining 27
chr1_-_184464810 6.40 ENSMUST00000048572.7
H2.0-like homeobox
chr14_+_55815817 6.38 ENSMUST00000174259.8
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr1_+_52158599 6.36 ENSMUST00000186574.7
ENSMUST00000070968.14
ENSMUST00000191435.7
ENSMUST00000186857.7
ENSMUST00000188681.7
signal transducer and activator of transcription 1
chr19_+_56385531 6.17 ENSMUST00000026062.10
caspase 7
chr5_+_115034997 6.00 ENSMUST00000031542.13
ENSMUST00000146072.8
ENSMUST00000150361.2
2'-5' oligoadenylate synthetase-like 2
chr9_+_96141317 5.96 ENSMUST00000165768.4
transcription factor Dp 2
chr3_+_27371168 5.94 ENSMUST00000046383.12
tumor necrosis factor (ligand) superfamily, member 10
chr9_+_96141299 5.93 ENSMUST00000179065.8
transcription factor Dp 2
chr3_-_137687284 5.92 ENSMUST00000136613.4
ENSMUST00000029806.13
dual adaptor for phosphotyrosine and 3-phosphoinositides 1
chr5_-_134258435 5.90 ENSMUST00000016094.13
ENSMUST00000111275.8
ENSMUST00000144086.2
neutrophil cytosolic factor 1
chr1_+_52158693 5.89 ENSMUST00000189347.7
signal transducer and activator of transcription 1
chr3_+_127584449 5.87 ENSMUST00000171621.3
TRAF-interacting protein with forkhead-associated domain
chr3_+_127584251 5.86 ENSMUST00000164447.3
TRAF-interacting protein with forkhead-associated domain
chr4_+_94627513 5.85 ENSMUST00000073939.13
ENSMUST00000102798.8
TEK receptor tyrosine kinase
chr17_-_79190002 5.81 ENSMUST00000024884.5
eukaryotic translation initiation factor 2-alpha kinase 2
chr19_+_3372296 5.76 ENSMUST00000237938.2
carnitine palmitoyltransferase 1a, liver
chr7_+_100742070 5.68 ENSMUST00000208439.2
FCH and double SH3 domains 2
chr19_+_29388312 5.65 ENSMUST00000112576.4
programmed cell death 1 ligand 2
chr19_-_34579356 5.25 ENSMUST00000168254.3
interferon induced protein with tetratricpeptide repeats 1B like 1
chr17_+_34138611 5.21 ENSMUST00000234247.2
TAP binding protein
chr7_-_25488060 5.16 ENSMUST00000002677.11
ENSMUST00000085948.11
AXL receptor tyrosine kinase
chr12_-_79054050 5.13 ENSMUST00000056660.13
ENSMUST00000174721.8
transmembrane protein 229B
chr14_+_55815580 5.11 ENSMUST00000174484.8
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr3_+_142266113 5.06 ENSMUST00000106221.8
guanylate binding protein 3
chr5_+_43673093 5.03 ENSMUST00000144558.3
C1q and tumor necrosis factor related protein 7
chr1_+_153625243 5.01 ENSMUST00000182722.8
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr14_+_40827108 5.00 ENSMUST00000224514.2
methionine adenosyltransferase I, alpha
chr4_+_42255693 4.99 ENSMUST00000178864.3
chemokine (C-C motif) ligand 21B (leucine)
chr11_+_31822211 4.97 ENSMUST00000020543.13
ENSMUST00000109412.9
cytoplasmic polyadenylation element binding protein 4
chr15_-_98816012 4.95 ENSMUST00000023736.10
limb region 1 like
chr16_+_24212284 4.93 ENSMUST00000038053.14
LIM domain containing preferred translocation partner in lipoma
chr1_+_52158721 4.92 ENSMUST00000186057.7
signal transducer and activator of transcription 1
chr1_+_153625161 4.85 ENSMUST00000086209.10
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr17_+_34138699 4.83 ENSMUST00000234320.2
TAP binding protein
chr12_-_80307110 4.82 ENSMUST00000021554.16
actinin, alpha 1
chr9_-_106353303 4.79 ENSMUST00000156426.8
poly (ADP-ribose) polymerase family, member 3
chr6_-_38331482 4.78 ENSMUST00000031850.10
ENSMUST00000114898.3
zinc finger CCCH type, antiviral 1
chr4_+_42114817 4.78 ENSMUST00000098123.4
predicted gene 13304
chr13_-_100454182 4.72 ENSMUST00000118574.8
NLR family, apoptosis inhibitory protein 6
chr11_+_119283887 4.70 ENSMUST00000093902.12
ENSMUST00000131035.10
ring finger protein 213
chr4_-_136626073 4.63 ENSMUST00000046285.6
complement component 1, q subcomponent, alpha polypeptide
chr3_+_20011201 4.60 ENSMUST00000091309.12
ENSMUST00000108329.8
ENSMUST00000003714.13
ceruloplasmin
chr19_+_29344846 4.60 ENSMUST00000016640.8
CD274 antigen
chr3_-_59038031 4.59 ENSMUST00000091112.6
ENSMUST00000065220.13
purinergic receptor P2Y, G-protein coupled, 14
chr11_+_115725140 4.58 ENSMUST00000173289.8
ENSMUST00000137900.2
LLGL2 scribble cell polarity complex component
chr4_+_41903610 4.56 ENSMUST00000098128.4
chemokine (C-C motif) ligand 21D
chr8_-_45786226 4.53 ENSMUST00000095328.6
cytochrome P450, family 4, subfamily v, polypeptide 3
chr18_-_39623698 4.52 ENSMUST00000115567.8
nuclear receptor subfamily 3, group C, member 1
chr3_+_20011251 4.51 ENSMUST00000108328.8
ceruloplasmin
chr3_+_142265904 4.46 ENSMUST00000128609.8
ENSMUST00000029935.14
guanylate binding protein 3
chr2_-_132095146 4.45 ENSMUST00000028817.7
proliferating cell nuclear antigen
chr3_-_144425819 4.44 ENSMUST00000199531.5
ENSMUST00000199854.5
SH3-domain GRB2-like B1 (endophilin)
chr17_+_75772567 4.43 ENSMUST00000234660.2
RAS, guanyl releasing protein 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
10.6 31.7 GO:0046967 cytosol to ER transport(GO:0046967)
10.2 30.5 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
7.8 47.0 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
6.2 24.9 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
6.0 24.1 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
5.7 17.2 GO:0034240 negative regulation of macrophage fusion(GO:0034240)
5.6 22.5 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
4.9 24.5 GO:0043321 regulation of natural killer cell degranulation(GO:0043321)
4.5 13.6 GO:0071626 mastication(GO:0071626) learned vocalization behavior(GO:0098583)
4.3 25.6 GO:0019805 quinolinate biosynthetic process(GO:0019805)
4.2 33.7 GO:0032020 ISG15-protein conjugation(GO:0032020)
4.1 12.4 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
4.1 8.1 GO:0002477 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481)
3.9 11.7 GO:0009087 methionine catabolic process(GO:0009087)
3.8 11.3 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
2.9 8.7 GO:0014739 positive regulation of muscle hyperplasia(GO:0014739)
2.8 39.8 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
2.8 11.1 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
2.7 19.0 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
2.7 77.7 GO:0035455 response to interferon-alpha(GO:0035455)
2.5 20.4 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
2.5 15.2 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
2.5 30.2 GO:0045345 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
2.5 10.0 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479) peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
2.5 37.5 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
2.4 16.6 GO:1904073 regulation of oligodendrocyte apoptotic process(GO:1900141) negative regulation of oligodendrocyte apoptotic process(GO:1900142) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
2.3 13.8 GO:1990166 protein localization to site of double-strand break(GO:1990166)
2.2 6.6 GO:0002501 MHC protein complex assembly(GO:0002396) peptide antigen assembly with MHC protein complex(GO:0002501)
2.0 91.7 GO:0035458 cellular response to interferon-beta(GO:0035458)
2.0 5.9 GO:0070947 neutrophil mediated killing of fungus(GO:0070947)
1.8 7.3 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
1.8 1.8 GO:0035456 response to interferon-beta(GO:0035456)
1.7 15.4 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
1.7 8.4 GO:0035546 detection of virus(GO:0009597) interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549)
1.7 8.4 GO:0048014 Tie signaling pathway(GO:0048014)
1.6 9.5 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
1.5 12.1 GO:0060700 regulation of ribonuclease activity(GO:0060700)
1.5 9.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
1.5 4.4 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
1.5 11.7 GO:0018377 protein myristoylation(GO:0018377)
1.5 4.4 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386) immunoglobulin transcytosis in epithelial cells(GO:0002414)
1.4 8.6 GO:0071918 urea transmembrane transport(GO:0071918)
1.4 10.0 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
1.4 17.1 GO:0033004 negative regulation of mast cell activation(GO:0033004)
1.3 16.0 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
1.3 6.4 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
1.3 5.1 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
1.3 8.8 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
1.3 12.5 GO:0032727 positive regulation of interferon-alpha production(GO:0032727)
1.2 6.2 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
1.2 5.9 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
1.1 4.6 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
1.1 5.6 GO:0035723 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
1.1 4.4 GO:0006272 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
1.1 10.7 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
1.1 10.5 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
1.0 3.1 GO:0006233 dTDP biosynthetic process(GO:0006233) dTDP metabolic process(GO:0046072)
1.0 17.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
1.0 3.0 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
1.0 12.7 GO:0070269 pyroptosis(GO:0070269)
1.0 11.7 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
1.0 25.7 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)
0.9 12.0 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.9 4.5 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.8 7.6 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.8 9.2 GO:0034340 response to type I interferon(GO:0034340)
0.8 11.9 GO:0032494 response to peptidoglycan(GO:0032494)
0.8 3.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.8 16.1 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.8 2.3 GO:1904735 negative regulation of electron carrier activity(GO:1904733) regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:1904735) negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:1904736)
0.7 13.2 GO:0006857 oligopeptide transport(GO:0006857)
0.7 16.7 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.7 4.6 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.6 5.8 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.6 10.2 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.6 20.2 GO:0035634 response to stilbenoid(GO:0035634)
0.6 12.5 GO:0031000 response to caffeine(GO:0031000)
0.6 17.2 GO:0042119 neutrophil activation(GO:0042119)
0.5 4.6 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.5 11.7 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.5 5.0 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.4 9.8 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.4 16.5 GO:0002360 T cell lineage commitment(GO:0002360)
0.4 4.7 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.4 4.2 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.4 2.9 GO:0007527 adult somatic muscle development(GO:0007527)
0.4 7.4 GO:0010818 T cell chemotaxis(GO:0010818)
0.4 1.9 GO:0031296 B cell costimulation(GO:0031296)
0.4 12.9 GO:0046688 response to copper ion(GO:0046688)
0.4 1.1 GO:1902867 negative regulation of neural retina development(GO:0061076) negative regulation of retina development in camera-type eye(GO:1902867) negative regulation of amacrine cell differentiation(GO:1902870)
0.3 2.4 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.3 2.9 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.3 7.1 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.3 14.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.3 3.8 GO:0046884 follicle-stimulating hormone secretion(GO:0046884)
0.3 14.0 GO:0048525 negative regulation of viral process(GO:0048525)
0.3 10.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.3 3.8 GO:0090527 actin filament reorganization(GO:0090527)
0.2 17.2 GO:0019882 antigen processing and presentation(GO:0019882)
0.2 7.2 GO:0042088 T-helper 1 type immune response(GO:0042088)
0.2 11.1 GO:0070207 protein homotrimerization(GO:0070207)
0.2 4.3 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.2 2.2 GO:0001955 blood vessel maturation(GO:0001955)
0.2 7.1 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.2 4.8 GO:0051639 actin filament network formation(GO:0051639)
0.2 5.7 GO:0032689 negative regulation of interferon-gamma production(GO:0032689)
0.2 7.5 GO:0006730 one-carbon metabolic process(GO:0006730)
0.2 5.0 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 1.9 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.1 2.9 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 3.2 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.1 1.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 5.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.7 GO:0048254 snoRNA localization(GO:0048254)
0.1 0.4 GO:0061386 closure of optic fissure(GO:0061386)
0.1 1.0 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.1 0.4 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.1 4.3 GO:0006953 acute-phase response(GO:0006953)
0.1 1.3 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.1 8.5 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 2.9 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 1.9 GO:0045910 negative regulation of DNA recombination(GO:0045910) positive regulation of chromosome segregation(GO:0051984)
0.1 2.9 GO:0010390 histone monoubiquitination(GO:0010390)
0.1 1.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 14.5 GO:0002250 adaptive immune response(GO:0002250)
0.1 0.2 GO:0021634 optic nerve formation(GO:0021634) optic chiasma development(GO:0061360) regulation of optic nerve formation(GO:2000595) positive regulation of optic nerve formation(GO:2000597)
0.0 0.3 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 12.5 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 4.9 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 3.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.0 GO:0051923 sulfation(GO:0051923)
0.0 4.7 GO:0019395 fatty acid oxidation(GO:0019395)
0.0 0.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 2.8 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 4.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 15.7 GO:0006935 chemotaxis(GO:0006935)
0.0 1.6 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 2.0 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 5.2 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 6.1 GO:0045087 innate immune response(GO:0045087)
0.0 3.6 GO:0051607 defense response to virus(GO:0051607)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.0 GO:0016584 nucleosome positioning(GO:0016584)
0.0 1.9 GO:0007338 single fertilization(GO:0007338)
0.0 0.1 GO:0070932 histone H3 deacetylation(GO:0070932)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 41.7 GO:0042825 TAP complex(GO:0042825)
4.3 25.7 GO:0008537 proteasome activator complex(GO:0008537)
2.8 16.5 GO:1990111 spermatoproteasome complex(GO:1990111)
2.4 16.9 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
2.3 37.0 GO:0020003 symbiont-containing vacuole(GO:0020003)
1.8 12.7 GO:0072557 IPAF inflammasome complex(GO:0072557)
1.7 16.6 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
1.6 26.2 GO:0043020 NADPH oxidase complex(GO:0043020)
1.6 4.8 GO:0032127 dense core granule membrane(GO:0032127)
1.6 17.1 GO:0042629 mast cell granule(GO:0042629)
1.5 4.4 GO:0070557 PCNA-p21 complex(GO:0070557)
1.2 5.9 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.8 47.0 GO:0015030 Cajal body(GO:0015030)
0.7 9.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.7 13.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.6 5.2 GO:0043657 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.6 6.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.4 6.6 GO:0044754 autolysosome(GO:0044754)
0.4 2.0 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.4 15.7 GO:0035861 site of double-strand break(GO:0035861)
0.3 46.0 GO:0016605 PML body(GO:0016605)
0.3 4.3 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.3 8.7 GO:0001891 phagocytic cup(GO:0001891)
0.2 0.7 GO:0070761 pre-snoRNP complex(GO:0070761)
0.2 32.3 GO:0072562 blood microparticle(GO:0072562)
0.2 5.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 12.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 19.9 GO:0005811 lipid particle(GO:0005811)
0.2 14.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.2 5.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.2 87.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 1.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 5.7 GO:0031594 neuromuscular junction(GO:0031594)
0.1 2.9 GO:0070938 filopodium membrane(GO:0031527) contractile ring(GO:0070938)
0.1 13.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 6.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 135.5 GO:0005730 nucleolus(GO:0005730)
0.1 4.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 7.9 GO:0009925 basal plasma membrane(GO:0009925)
0.1 19.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 11.4 GO:0016363 nuclear matrix(GO:0016363)
0.1 16.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 1.9 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 11.4 GO:0031225 anchored component of membrane(GO:0031225)
0.1 6.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 8.4 GO:0032587 ruffle membrane(GO:0032587)
0.1 4.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 6.9 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 17.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 12.9 GO:0005635 nuclear envelope(GO:0005635)
0.0 30.6 GO:0009986 cell surface(GO:0009986)
0.0 4.7 GO:0005581 collagen trimer(GO:0005581)
0.0 8.8 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 1.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 140.9 GO:0005829 cytosol(GO:0005829)
0.0 6.1 GO:0000323 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 40.4 GO:0005615 extracellular space(GO:0005615)
0.0 1.1 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 1.3 GO:0005882 intermediate filament(GO:0005882)
0.0 2.9 GO:0005874 microtubule(GO:0005874)
0.0 23.8 GO:0005576 extracellular region(GO:0005576)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
10.6 31.7 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
9.4 47.0 GO:0008859 exoribonuclease II activity(GO:0008859)
8.3 24.9 GO:0031726 receptor signaling protein tyrosine kinase activator activity(GO:0030298) CCR1 chemokine receptor binding(GO:0031726)
4.8 57.5 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
4.3 12.9 GO:0003692 left-handed Z-DNA binding(GO:0003692)
3.5 14.0 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
3.4 17.2 GO:0019767 IgE receptor activity(GO:0019767)
3.3 16.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
3.3 9.8 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
2.9 11.7 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
2.7 24.5 GO:0016936 galactoside binding(GO:0016936)
2.7 16.1 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
2.5 10.0 GO:0046979 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
2.3 25.7 GO:0061133 endopeptidase activator activity(GO:0061133)
2.3 70.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
2.3 25.6 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
2.2 26.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
2.1 10.3 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
2.0 5.9 GO:0005174 CD40 receptor binding(GO:0005174)
1.9 5.8 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
1.7 17.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
1.6 13.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
1.5 4.4 GO:0032139 DNA polymerase processivity factor activity(GO:0030337) dinucleotide insertion or deletion binding(GO:0032139)
1.5 8.8 GO:0038051 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
1.5 7.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
1.5 5.8 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
1.3 12.8 GO:0004064 arylesterase activity(GO:0004064)
1.2 8.6 GO:0015265 urea channel activity(GO:0015265)
1.2 39.8 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
1.1 14.8 GO:0001069 regulatory region RNA binding(GO:0001069)
1.1 10.2 GO:0031849 olfactory receptor binding(GO:0031849)
1.1 11.3 GO:0051434 BH3 domain binding(GO:0051434)
1.1 17.3 GO:0031386 protein tag(GO:0031386)
1.1 12.9 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
1.0 3.1 GO:0004798 thymidylate kinase activity(GO:0004798)
1.0 3.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
1.0 16.9 GO:0050897 cobalt ion binding(GO:0050897)
0.9 21.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.9 8.6 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.8 12.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.7 4.5 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.7 6.7 GO:0048019 receptor antagonist activity(GO:0048019)
0.7 16.6 GO:0070628 proteasome binding(GO:0070628)
0.6 4.4 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.6 13.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.6 2.9 GO:0045322 unmethylated CpG binding(GO:0045322)
0.6 25.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.6 7.4 GO:0008009 chemokine activity(GO:0008009)
0.5 7.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.5 144.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.5 24.1 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.4 6.2 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.4 2.4 GO:0033142 progesterone receptor binding(GO:0033142)
0.3 2.0 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.3 20.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.3 1.9 GO:0000403 Y-form DNA binding(GO:0000403)
0.3 17.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.3 14.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.3 6.6 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.3 1.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.3 5.0 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.3 3.1 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.2 9.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 45.8 GO:0004386 helicase activity(GO:0004386)
0.2 7.7 GO:0017166 vinculin binding(GO:0017166)
0.2 1.9 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.2 12.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 67.3 GO:0003924 GTPase activity(GO:0003924)
0.2 9.8 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.2 4.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.2 20.1 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.2 4.4 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
0.1 11.7 GO:0019843 rRNA binding(GO:0019843)
0.1 9.6 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 0.7 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 5.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 2.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 3.2 GO:0005537 mannose binding(GO:0005537)
0.1 26.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.4 GO:0039706 co-receptor binding(GO:0039706)
0.1 11.5 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 2.0 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 6.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 7.4 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 14.4 GO:0015293 symporter activity(GO:0015293)
0.1 51.2 GO:0008270 zinc ion binding(GO:0008270)
0.1 1.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.4 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 2.3 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 7.6 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.0 44.7 GO:0003677 DNA binding(GO:0003677)
0.0 4.8 GO:0042393 histone binding(GO:0042393)
0.0 4.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 13.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 4.1 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 0.5 GO:0042605 peptide antigen binding(GO:0042605)
0.0 1.0 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 3.6 GO:0051015 actin filament binding(GO:0051015)
0.0 1.2 GO:0051219 phosphoprotein binding(GO:0051219)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 30.3 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.6 29.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.6 17.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.5 16.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.4 16.9 PID MYC PATHWAY C-MYC pathway
0.4 34.9 PID IL12 2PATHWAY IL12-mediated signaling events
0.4 28.4 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.3 26.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.3 6.2 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.3 10.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.3 8.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.3 7.4 PID TRAIL PATHWAY TRAIL signaling pathway
0.3 13.7 PID RAS PATHWAY Regulation of Ras family activation
0.3 47.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.2 7.9 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.2 16.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.2 7.3 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.2 24.0 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.2 41.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 12.1 PID E2F PATHWAY E2F transcription factor network
0.2 3.0 PID S1P S1P1 PATHWAY S1P1 pathway
0.2 10.5 PID PLK1 PATHWAY PLK1 signaling events
0.2 12.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 4.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 5.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 8.5 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 0.5 PID IL27 PATHWAY IL27-mediated signaling events
0.1 2.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 11.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 10.3 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 2.0 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 235.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
2.7 8.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
2.1 40.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
1.5 63.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
1.4 12.5 REACTOME DEFENSINS Genes involved in Defensins
1.4 22.1 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
1.3 27.9 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
1.1 15.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
1.0 53.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.8 10.3 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.7 7.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.7 16.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.7 56.0 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.7 17.3 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.6 39.8 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.5 25.5 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.5 8.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.4 4.8 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.3 11.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.3 3.8 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.3 12.9 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.3 13.7 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.3 7.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 8.6 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.2 5.8 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.2 6.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 10.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.2 4.8 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.2 13.2 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.2 8.8 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 3.8 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 2.0 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 13.7 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.1 4.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 3.0 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 5.8 REACTOME INTERFERON SIGNALING Genes involved in Interferon Signaling
0.1 2.0 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 9.2 REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION Genes involved in Class I MHC mediated antigen processing & presentation