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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Tbx4

Z-value: 0.74

Motif logo

Transcription factors associated with Tbx4

Gene Symbol Gene ID Gene Info
ENSMUSG00000000094.13 Tbx4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tbx4mm39_v1_chr11_+_85780807_857808890.641.2e-09Click!

Activity profile of Tbx4 motif

Sorted Z-values of Tbx4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbx4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_+_72281587 6.59 ENSMUST00000183018.8
ENSMUST00000182014.10
surfactant associated protein B
chr9_-_99592116 5.77 ENSMUST00000035048.12
claudin 18
chr9_-_99592058 5.68 ENSMUST00000136429.8
claudin 18
chr2_-_147888816 5.53 ENSMUST00000172928.2
ENSMUST00000047315.10
forkhead box A2
chr2_+_164404499 5.41 ENSMUST00000017867.10
ENSMUST00000109344.9
ENSMUST00000109345.9
WAP four-disulfide core domain 2
chr19_+_20579322 4.98 ENSMUST00000087638.4
aldehyde dehydrogenase family 1, subfamily A1
chr7_+_79460475 4.50 ENSMUST00000107394.3
mesoderm posterior 2
chr2_-_147887810 4.00 ENSMUST00000109964.8
forkhead box A2
chr7_-_103463120 3.92 ENSMUST00000098192.4
hemoglobin, beta adult t chain
chr7_-_79443536 3.60 ENSMUST00000032760.6
mesoderm posterior 1
chr7_-_119694400 2.81 ENSMUST00000209154.3
ENSMUST00000046993.4
dynein, axonemal, heavy chain 3
chr15_+_38219447 2.80 ENSMUST00000081966.5
outer dense fiber of sperm tails 1
chr5_+_17779721 2.79 ENSMUST00000169603.2
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr14_-_70449438 2.79 ENSMUST00000227929.2
sorbin and SH3 domain containing 3
chr4_-_133746138 2.74 ENSMUST00000051674.3
lin-28 homolog A (C. elegans)
chr4_+_148085179 2.48 ENSMUST00000103230.5
natriuretic peptide type A
chr1_+_40619215 2.46 ENSMUST00000027233.9
solute carrier family 9 (sodium/hydrogen exchanger), member 4
chr10_+_86541675 2.35 ENSMUST00000075632.14
ENSMUST00000217747.2
ENSMUST00000061458.9
tetratricopeptide repeat domain 41
chr15_-_11905697 2.27 ENSMUST00000066529.5
ENSMUST00000228603.2
natriuretic peptide receptor 3
chr4_-_19922599 2.21 ENSMUST00000029900.6
ATPase, H+ transporting, lysosomal V0 subunit D2
chr4_+_43641262 2.01 ENSMUST00000123351.8
ENSMUST00000128549.3
natriuretic peptide receptor 2
chr11_-_94398162 1.90 ENSMUST00000040692.9
MYCBP associated protein
chr7_-_81216687 1.86 ENSMUST00000042318.6
fibronectin type III and SPRY domain containing 2
chr16_+_62635039 1.85 ENSMUST00000055557.6
syntaxin 19
chr8_+_55024446 1.78 ENSMUST00000239166.2
ENSMUST00000239106.2
ENSMUST00000239152.2
ankyrin repeat and SOCs box-containing 5
chr19_-_28941264 1.77 ENSMUST00000161813.2
spermatogenesis associated 6 like
chr2_+_103254465 1.73 ENSMUST00000171693.8
E74-like factor 5
chr3_-_30194559 1.70 ENSMUST00000108271.10
MDS1 and EVI1 complex locus
chr6_+_139987275 1.70 ENSMUST00000043797.6
capping protein (actin filament) muscle Z-line, alpha 3
chr4_-_46404224 1.64 ENSMUST00000107764.9
hemogen
chr6_+_15196950 1.57 ENSMUST00000140557.8
ENSMUST00000131414.8
ENSMUST00000115469.8
forkhead box P2
chr18_+_32948436 1.54 ENSMUST00000025237.5
thymic stromal lymphopoietin
chr15_-_78687216 1.51 ENSMUST00000164826.8
caspase recruitment domain family, member 10
chr2_+_103254401 1.51 ENSMUST00000028609.14
E74-like factor 5
chr18_-_65527078 1.46 ENSMUST00000035548.16
alpha-kinase 2
chr18_-_60724855 1.46 ENSMUST00000056533.9
myozenin 3
chr7_-_100307601 1.41 ENSMUST00000138830.2
ENSMUST00000107044.10
ENSMUST00000116287.9
pleckstrin homology domain containing, family B (evectins) member 1
chr19_-_45224251 1.40 ENSMUST00000099401.6
ladybird homeobox 1
chr19_-_37184692 1.39 ENSMUST00000132580.8
ENSMUST00000079754.11
ENSMUST00000136286.8
ENSMUST00000126188.8
ENSMUST00000126781.2
cytoplasmic polyadenylation element binding protein 3
chr10_+_97528915 1.37 ENSMUST00000060703.6
coiled-coil glutamate-rich protein 1
chr7_+_130179063 1.35 ENSMUST00000207918.2
ENSMUST00000215492.2
ENSMUST00000084513.12
ENSMUST00000059145.14
transforming, acidic coiled-coil containing protein 2
chr12_+_119356318 1.33 ENSMUST00000221866.2
metastasis associated in colon cancer 1
chr6_-_139987135 1.31 ENSMUST00000032356.13
phospholipase C, zeta 1
chr8_+_46338557 1.30 ENSMUST00000210422.2
PDZ and LIM domain 3
chr11_-_23720953 1.29 ENSMUST00000102864.5
reticuloendotheliosis oncogene
chr7_-_73663422 1.27 ENSMUST00000026896.10
ENSMUST00000191970.2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr4_+_117706559 1.23 ENSMUST00000163288.2
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr10_+_87697155 1.19 ENSMUST00000122100.3
insulin-like growth factor 1
chr16_-_32617783 1.16 ENSMUST00000115116.8
ENSMUST00000041123.9
mucin 20
chr1_+_74582044 1.15 ENSMUST00000113749.8
ENSMUST00000067916.13
ENSMUST00000113747.8
ENSMUST00000113750.8
phospholipase C, delta 4
chr9_+_102885156 1.14 ENSMUST00000035148.13
solute carrier organic anion transporter family, member 2a1
chr16_+_87350202 1.13 ENSMUST00000026700.8
Map3k7 C-terminal like
chr7_-_100307571 1.10 ENSMUST00000107043.8
pleckstrin homology domain containing, family B (evectins) member 1
chr10_-_14420725 1.09 ENSMUST00000041168.6
ENSMUST00000238680.2
adhesion G protein-coupled receptor G6
chr4_+_117706390 1.08 ENSMUST00000132043.9
ENSMUST00000169990.8
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr2_+_32498997 1.07 ENSMUST00000143625.2
ENSMUST00000128811.2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chrX_+_167819606 1.05 ENSMUST00000087016.11
ENSMUST00000112129.8
ENSMUST00000112131.9
Rho GTPase activating protein 6
chr14_-_30665232 1.05 ENSMUST00000006704.17
ENSMUST00000163118.2
inter-alpha trypsin inhibitor, heavy chain 1
chr19_+_37686240 1.04 ENSMUST00000025946.7
cytochrome P450, family 26, subfamily a, polypeptide 1
chr1_+_59563453 0.97 ENSMUST00000186434.3
predicted gene 973
chr1_-_126758520 0.96 ENSMUST00000162646.8
NCK-associated protein 5
chr11_-_22236795 0.95 ENSMUST00000180360.8
ENSMUST00000109563.9
EH domain binding protein 1
chr2_+_103800553 0.94 ENSMUST00000111140.3
ENSMUST00000111139.3
LIM domain only 2
chr6_+_42263609 0.93 ENSMUST00000238845.2
ENSMUST00000031894.13
chloride channel, voltage-sensitive 1
chr1_-_126758369 0.91 ENSMUST00000112583.8
ENSMUST00000094609.10
NCK-associated protein 5
chr7_+_4240697 0.89 ENSMUST00000117550.2
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
chr9_-_107486381 0.89 ENSMUST00000102531.7
ENSMUST00000102530.8
ENSMUST00000195057.2
ENSMUST00000102532.10
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr8_+_46338498 0.88 ENSMUST00000034053.7
PDZ and LIM domain 3
chr4_-_72770859 0.87 ENSMUST00000179234.2
ENSMUST00000078617.5
aldolase 1 A, retrogene 1
chr13_+_81034214 0.82 ENSMUST00000161441.2
arrestin domain containing 3
chr3_+_40905066 0.79 ENSMUST00000191805.7
La ribonucleoprotein domain family, member 1B
chr9_+_71123061 0.76 ENSMUST00000034723.6
aldehyde dehydrogenase family 1, subfamily A2
chrX_+_132809166 0.75 ENSMUST00000033606.15
sushi-repeat-containing protein, X-linked 2
chr7_-_108529375 0.75 ENSMUST00000055745.5
NLR family, pyrin domain containing 10
chr12_-_31684588 0.74 ENSMUST00000020979.9
ENSMUST00000177962.9
B cell receptor associated protein 29
chr17_+_35878332 0.74 ENSMUST00000044326.5
RIKEN cDNA 2300002M23 gene
chr13_-_89890609 0.72 ENSMUST00000109546.9
versican
chr9_+_69902697 0.71 ENSMUST00000165389.8
BCL2/adenovirus E1B interacting protein 2
chr6_-_52141796 0.71 ENSMUST00000014848.11
homeobox A2
chr19_-_10282218 0.67 ENSMUST00000039327.11
diacylglycerol lipase, alpha
chr3_+_40905216 0.65 ENSMUST00000191872.6
ENSMUST00000200432.2
La ribonucleoprotein domain family, member 1B
chr11_+_95304903 0.63 ENSMUST00000107724.9
ENSMUST00000150884.8
ENSMUST00000107722.8
ENSMUST00000127713.2
speckle-type BTB/POZ protein
chr13_-_96678844 0.62 ENSMUST00000223475.2
polymerase (DNA directed), kappa
chr15_+_10952418 0.60 ENSMUST00000022853.15
ENSMUST00000110523.2
C1q and tumor necrosis factor related protein 3
chr18_+_65715460 0.57 ENSMUST00000169679.8
ENSMUST00000183326.2
zinc finger protein 532
chr2_+_138120401 0.57 ENSMUST00000075410.5
BTB (POZ) domain containing 3
chr6_-_126143710 0.56 ENSMUST00000050484.9
neurotrophin 3
chr6_+_42263644 0.53 ENSMUST00000163936.8
chloride channel, voltage-sensitive 1
chr17_+_35354655 0.52 ENSMUST00000174478.8
ENSMUST00000174281.9
ENSMUST00000173550.8
BCL2-associated athanogene 6
chr11_+_96214078 0.49 ENSMUST00000093944.10
homeobox B3
chr9_-_40915858 0.48 ENSMUST00000188848.8
ENSMUST00000034519.13
cytotoxic and regulatory T cell molecule
chr12_-_56392646 0.48 ENSMUST00000021416.9
MAP3K12 binding inhibitory protein 1
chr11_-_83959175 0.47 ENSMUST00000100705.11
dual specificity phosphatase 14
chr10_-_86541349 0.46 ENSMUST00000020238.14
heat shock protein 90, beta (Grp94), member 1
chr4_-_42665763 0.46 ENSMUST00000238770.2
interleukin 11 receptor, alpha chain 2
chr13_+_113346193 0.46 ENSMUST00000038144.9
endothelial cell-specific molecule 1
chr4_-_42168603 0.45 ENSMUST00000098121.4
predicted gene 13305
chr4_+_42950367 0.45 ENSMUST00000084662.12
DnaJ heat shock protein family (Hsp40) member B5
chr3_-_75464066 0.45 ENSMUST00000162138.2
ENSMUST00000029424.12
ENSMUST00000161137.8
programmed cell death 10
chr16_-_32630847 0.44 ENSMUST00000179384.3
somatomedin B domain containing 1
chrM_+_9459 0.44 ENSMUST00000082411.1
mitochondrially encoded NADH dehydrogenase 3
chr7_+_89779564 0.41 ENSMUST00000208742.2
ENSMUST00000049537.9
phosphatidylinositol binding clathrin assembly protein
chr11_+_78068931 0.41 ENSMUST00000147819.8
TLC domain containing 1
chr16_+_84631789 0.41 ENSMUST00000114184.8
GA repeat binding protein, alpha
chr11_+_23256883 0.39 ENSMUST00000180046.8
ubiquitin specific peptidase 34
chr18_+_5591864 0.39 ENSMUST00000025081.13
ENSMUST00000159390.8
zinc finger E-box binding homeobox 1
chrM_+_10167 0.38 ENSMUST00000082414.1
mitochondrially encoded NADH dehydrogenase 4
chr2_+_136733421 0.37 ENSMUST00000141463.8
SLX4 interacting protein
chr6_+_29398919 0.36 ENSMUST00000181464.8
ENSMUST00000180829.8
coiled-coil domain containing 136
chr14_+_45588632 0.36 ENSMUST00000228818.2
serine/threonine/tyrosine interaction protein
chr9_-_102231884 0.36 ENSMUST00000035129.14
ENSMUST00000085169.12
ENSMUST00000149800.3
Eph receptor B1
chrX_+_158623460 0.34 ENSMUST00000112451.8
ENSMUST00000112453.9
SH3-domain kinase binding protein 1
chr11_-_99494134 0.33 ENSMUST00000072306.4
predicted gene 11938
chr9_+_108174052 0.33 ENSMUST00000035230.7
aminomethyltransferase
chr16_-_50151350 0.32 ENSMUST00000114488.8
bobby sox HMG box containing
chrM_+_9870 0.32 ENSMUST00000084013.1
mitochondrially encoded NADH dehydrogenase 4L
chr9_-_40915895 0.31 ENSMUST00000180384.3
cytotoxic and regulatory T cell molecule
chr3_-_121056944 0.30 ENSMUST00000128909.8
ENSMUST00000029777.14
TLC domain containing 4
chr7_-_28001624 0.30 ENSMUST00000108315.4
delta like canonical Notch ligand 3
chr7_-_141850806 0.30 ENSMUST00000084413.7
ENSMUST00000188274.2
keratin associated protein 5-1
chr16_+_84631956 0.29 ENSMUST00000009120.8
GA repeat binding protein, alpha
chr13_-_96678987 0.29 ENSMUST00000022172.12
polymerase (DNA directed), kappa
chr3_+_51323383 0.27 ENSMUST00000029303.13
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr18_-_34505544 0.26 ENSMUST00000236887.2
receptor accessory protein 5
chr9_+_107468146 0.26 ENSMUST00000195746.2
interferon-related developmental regulator 2
chr7_-_28078671 0.25 ENSMUST00000209061.2
zinc finger protein 36
chr5_+_120651158 0.24 ENSMUST00000111889.2
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr6_-_145811274 0.24 ENSMUST00000032386.11
basic helix-loop-helix family, member e41
chr7_-_115423934 0.22 ENSMUST00000169129.8
SRY (sex determining region Y)-box 6
chr2_+_52747855 0.22 ENSMUST00000155586.9
ENSMUST00000090952.11
ENSMUST00000127122.9
ENSMUST00000049483.14
ENSMUST00000050719.13
formin-like 2
chr7_+_46445512 0.21 ENSMUST00000006774.11
ENSMUST00000165031.8
general transcription factor II H, polypeptide 1
chr7_+_45890379 0.21 ENSMUST00000164538.2
otogelin
chr8_-_46605196 0.20 ENSMUST00000110378.9
sorting nexin 25
chr11_+_121128042 0.19 ENSMUST00000103015.4
nuclear prelamin A recognition factor
chr1_+_171156568 0.19 ENSMUST00000111300.8
death effector domain-containing
chr14_-_55762395 0.19 ENSMUST00000228287.2
neural retina leucine zipper gene
chr12_-_11258973 0.18 ENSMUST00000049877.3
mesogenin 1
chr18_+_36414122 0.18 ENSMUST00000051301.6
purine rich element binding protein A
chr9_+_106247943 0.16 ENSMUST00000173748.2
dual specificity phosphatase 7
chr8_-_32408786 0.15 ENSMUST00000239000.2
neuregulin 1
chr11_-_106192627 0.13 ENSMUST00000103071.4
growth hormone
chr14_-_55762432 0.13 ENSMUST00000062232.15
neural retina leucine zipper gene
chr14_+_45588509 0.11 ENSMUST00000226873.2
serine/threonine/tyrosine interaction protein
chr16_-_23807602 0.11 ENSMUST00000023151.6
B cell leukemia/lymphoma 6
chr11_-_117859997 0.10 ENSMUST00000054002.4
suppressor of cytokine signaling 3
chr2_+_54326329 0.10 ENSMUST00000112636.8
ENSMUST00000112635.8
ENSMUST00000112634.8
polypeptide N-acetylgalactosaminyltransferase 13
chr6_-_145811028 0.10 ENSMUST00000111703.2
basic helix-loop-helix family, member e41
chr14_-_55762416 0.09 ENSMUST00000178694.3
neural retina leucine zipper gene
chr13_-_111626562 0.09 ENSMUST00000091236.11
ENSMUST00000047627.14
GC-rich promoter binding protein 1
chr17_-_49871291 0.08 ENSMUST00000224595.2
ENSMUST00000057610.8
dishevelled associated activator of morphogenesis 2
chr8_-_32408380 0.07 ENSMUST00000208497.3
ENSMUST00000207584.3
neuregulin 1
chr11_-_99511257 0.07 ENSMUST00000073853.3
predicted gene 11562
chr14_+_53574579 0.07 ENSMUST00000179580.3
T cell receptor alpha variable 13N-3
chr13_-_43457626 0.04 ENSMUST00000055341.7
glucose-fructose oxidoreductase domain containing 1
chr2_+_130038463 0.04 ENSMUST00000166774.3
transmembrane channel-like gene family 2
chrX_+_41239872 0.04 ENSMUST00000123245.8
stromal antigen 2
chr11_-_98040377 0.03 ENSMUST00000103143.10
F-box and leucine-rich repeat protein 20
chr8_-_32408864 0.03 ENSMUST00000073884.7
ENSMUST00000238812.2
neuregulin 1
chr11_-_69791774 0.03 ENSMUST00000102580.10
RIKEN cDNA 2810408A11 gene
chr9_+_72952115 0.02 ENSMUST00000184146.8
ENSMUST00000034722.5
RAB27A, member RAS oncogene family
chr4_-_133399909 0.02 ENSMUST00000062118.11
ENSMUST00000067902.13
phosphatidylinositol glycan anchor biosynthesis, class V
chr13_+_96679233 0.01 ENSMUST00000077672.12
ENSMUST00000109444.3
ceramide transporter 1
chr14_+_52131067 0.01 ENSMUST00000047726.12
solute carrier family 39 (zinc transporter), member 2
chr19_+_55882942 0.00 ENSMUST00000142291.8
transcription factor 7 like 2, T cell specific, HMG box

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.5 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
1.6 11.5 GO:2001205 negative regulation of osteoclast development(GO:2001205)
1.2 3.6 GO:0090081 regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.8 2.3 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.6 5.7 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.6 2.5 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.6 4.5 GO:0008078 mesodermal cell migration(GO:0008078)
0.5 3.2 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.5 1.4 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.5 2.7 GO:0010587 miRNA catabolic process(GO:0010587)
0.3 2.8 GO:0003350 pulmonary myocardium development(GO:0003350)
0.3 0.8 GO:0002355 detection of tumor cell(GO:0002355)
0.2 0.7 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 2.3 GO:0002158 osteoclast proliferation(GO:0002158)
0.2 2.0 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.2 2.5 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 0.8 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.2 2.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 0.7 GO:0021658 rhombomere 3 morphogenesis(GO:0021658)
0.2 1.2 GO:1904073 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.2 0.7 GO:0099541 diacylglycerol catabolic process(GO:0046340) trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.2 2.8 GO:0036159 inner dynein arm assembly(GO:0036159)
0.2 0.5 GO:0045204 MAPK export from nucleus(GO:0045204)
0.2 0.5 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 1.0 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.1 1.3 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.5 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1 0.3 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 1.7 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 0.6 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 1.5 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.9 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 1.6 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.8 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.1 1.4 GO:0048664 neuron fate determination(GO:0048664)
0.1 1.9 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 1.1 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.1 0.2 GO:1904582 positive regulation of intracellular mRNA localization(GO:1904582)
0.1 0.4 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.5 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.7 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 2.2 GO:0007035 vacuolar acidification(GO:0007035)
0.1 1.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.6 GO:0070163 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
0.1 5.8 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.1 0.6 GO:0007403 glial cell fate determination(GO:0007403)
0.1 0.4 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 1.3 GO:0007343 egg activation(GO:0007343)
0.1 0.5 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 1.2 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.1 0.8 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.3 GO:0007386 compartment pattern specification(GO:0007386)
0.1 1.3 GO:0022027 interkinetic nuclear migration(GO:0022027) astral microtubule organization(GO:0030953)
0.1 0.9 GO:0097067 negative regulation of erythrocyte differentiation(GO:0045647) cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.5 GO:0051189 molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 1.1 GO:0015732 prostaglandin transport(GO:0015732)
0.0 1.7 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.4 GO:2001015 skeletal muscle satellite cell differentiation(GO:0014816) negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.0 1.1 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.2 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.1 GO:0043380 regulation of memory T cell differentiation(GO:0043380)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.5 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.2 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.4 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.3 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 1.0 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.4 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 1.0 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.2 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.6 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.2 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 1.5 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.5 6.6 GO:0097208 alveolar lamellar body(GO:0097208)
0.2 2.5 GO:0042629 mast cell granule(GO:0042629)
0.2 2.8 GO:0036156 inner dynein arm(GO:0036156)
0.2 2.8 GO:0001520 outer dense fiber(GO:0001520)
0.1 2.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 1.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 1.7 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 1.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 2.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.4 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 1.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.5 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 11.5 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 1.9 GO:0031201 SNARE complex(GO:0031201)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.7 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 1.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 2.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 1.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.8 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 3.0 GO:0030018 Z disc(GO:0030018)
0.0 0.4 GO:0002080 acrosomal membrane(GO:0002080)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.4 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
1.0 5.0 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
1.0 3.9 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.7 4.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.3 1.5 GO:0051373 FATZ binding(GO:0051373)
0.2 2.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.2 1.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 2.7 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 0.8 GO:0031699 beta-3 adrenergic receptor binding(GO:0031699)
0.2 3.7 GO:0038191 neuropilin binding(GO:0038191)
0.2 0.8 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.2 0.7 GO:0070052 collagen V binding(GO:0070052)
0.2 1.0 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.2 2.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.2 0.5 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 10.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 0.3 GO:0071820 N-box binding(GO:0071820)
0.1 1.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 2.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 2.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 2.8 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 1.0 GO:0016004 phospholipase activator activity(GO:0016004)
0.1 2.8 GO:0017166 vinculin binding(GO:0017166)
0.1 2.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.6 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 1.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.2 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.1 1.1 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 1.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 1.2 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.0 2.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.5 GO:0046790 virion binding(GO:0046790)
0.0 0.5 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 1.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.1 GO:0043236 laminin binding(GO:0043236)
0.0 0.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.5 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 3.6 GO:0035326 enhancer binding(GO:0035326)
0.0 0.4 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 11.0 GO:0005198 structural molecule activity(GO:0005198)
0.0 4.2 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 3.0 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 7.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.2 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 9.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 2.5 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.8 PID SHP2 PATHWAY SHP2 signaling
0.0 0.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.6 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.3 11.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.3 9.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 2.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 2.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 2.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 2.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.0 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.3 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)