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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Tbx5

Z-value: 0.95

Motif logo

Transcription factors associated with Tbx5

Gene Symbol Gene ID Gene Info
ENSMUSG00000018263.12 Tbx5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tbx5mm39_v1_chr5_+_119970733_119970780-0.047.5e-01Click!

Activity profile of Tbx5 motif

Sorted Z-values of Tbx5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbx5

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_-_100396635 5.15 ENSMUST00000061455.9
terminal nucleotidyltransferase 5C
chr16_-_10614679 4.39 ENSMUST00000023144.6
protamine 1
chr7_-_44888532 4.02 ENSMUST00000033063.15
CD37 antigen
chr4_-_133746138 4.02 ENSMUST00000051674.3
lin-28 homolog A (C. elegans)
chrX_+_99773523 3.97 ENSMUST00000019503.14
glycerophosphodiester phosphodiesterase domain containing 2
chr3_-_92493507 3.94 ENSMUST00000194965.6
sperm mitochondria-associated cysteine-rich protein
chrX_+_99773784 3.80 ENSMUST00000113744.2
glycerophosphodiester phosphodiesterase domain containing 2
chr10_+_97528915 3.54 ENSMUST00000060703.6
coiled-coil glutamate-rich protein 1
chr19_-_6902735 3.49 ENSMUST00000057716.6
cation channel sperm associated auxiliary subunit zeta
chr7_-_44888220 3.40 ENSMUST00000210372.2
ENSMUST00000209779.2
ENSMUST00000098461.10
ENSMUST00000211373.2
CD37 antigen
chr6_+_125026915 3.36 ENSMUST00000088294.12
ENSMUST00000032481.8
proacrosin binding protein
chr2_-_32277773 3.34 ENSMUST00000050785.14
lipocalin 2
chr19_-_6902698 3.33 ENSMUST00000237380.2
cation channel sperm associated auxiliary subunit zeta
chr5_-_100867520 3.32 ENSMUST00000112908.2
ENSMUST00000045617.15
heparanase
chr15_-_78280099 3.30 ENSMUST00000229878.2
ENSMUST00000165170.8
ENSMUST00000074380.14
testis expressed 33
chr7_+_28682253 3.24 ENSMUST00000085835.8
mitogen-activated protein kinase kinase kinase kinase 1
chr15_-_103163860 3.20 ENSMUST00000075192.13
nuclear factor, erythroid derived 2
chr6_-_136638926 3.11 ENSMUST00000032336.7
phospholipase B domain containing 1
chr1_-_156936197 3.05 ENSMUST00000187546.7
ENSMUST00000118207.8
ENSMUST00000027884.13
ENSMUST00000121911.8
testis expressed 35
chr6_-_135287372 3.02 ENSMUST00000050471.4
phosphatidylethanolamine binding protein 2
chr11_-_83412952 2.94 ENSMUST00000019069.4
HEAT repeat containing 9
chr15_-_89294434 2.86 ENSMUST00000109314.9
synaptonemal complex central element protein 3
chr8_-_105019806 2.81 ENSMUST00000212492.2
ENSMUST00000034344.10
CKLF-like MARVEL transmembrane domain containing 2A
chr11_-_118233326 2.79 ENSMUST00000103024.4
CEP295 N-terminal like
chr3_-_95214102 2.76 ENSMUST00000107183.8
ENSMUST00000164406.8
ENSMUST00000123365.2
annexin A9
chr17_+_48571298 2.72 ENSMUST00000059873.14
ENSMUST00000154335.8
ENSMUST00000136272.8
ENSMUST00000125426.8
ENSMUST00000153420.2
triggering receptor expressed on myeloid cells-like 4
chr6_+_41661356 2.69 ENSMUST00000031900.6
LLLL and CFNLAS motif containing 1
chr18_-_46345661 2.65 ENSMUST00000037011.6
tripartite motif-containing 36
chr8_+_84116507 2.61 ENSMUST00000109831.3
calmegin
chr4_-_41517326 2.59 ENSMUST00000030152.13
ENSMUST00000095126.5
RIKEN cDNA 1110017D15 gene
chr2_-_32278245 2.57 ENSMUST00000192241.2
lipocalin 2
chr7_-_44888465 2.56 ENSMUST00000210078.2
CD37 antigen
chr14_-_56322654 2.51 ENSMUST00000015594.9
mast cell protease 8
chr3_-_95214443 2.51 ENSMUST00000015846.9
annexin A9
chr2_+_103800459 2.49 ENSMUST00000111143.8
ENSMUST00000138815.2
LIM domain only 2
chr2_+_103800553 2.49 ENSMUST00000111140.3
ENSMUST00000111139.3
LIM domain only 2
chr2_+_24076481 2.46 ENSMUST00000057567.3
interleukin 1 family, member 9
chr8_+_84116463 2.40 ENSMUST00000002259.13
calmegin
chr6_-_52168675 2.39 ENSMUST00000101395.3
homeobox A4
chr8_-_106660470 2.36 ENSMUST00000034368.8
chymotrypsin-like
chr1_-_131172903 2.30 ENSMUST00000027688.15
ENSMUST00000112442.2
Ras association (RalGDS/AF-6) domain family member 5
chr3_-_20329823 2.23 ENSMUST00000011607.6
carboxypeptidase B1 (tissue)
chrX_-_36253309 2.19 ENSMUST00000060474.14
ENSMUST00000053456.11
ENSMUST00000115239.10
septin 6
chr12_+_51640097 2.19 ENSMUST00000164782.10
ENSMUST00000085412.7
cochlin
chr6_+_139987275 2.17 ENSMUST00000043797.6
capping protein (actin filament) muscle Z-line, alpha 3
chr18_-_55123153 2.14 ENSMUST00000064763.7
zinc finger protein 608
chr1_-_172156884 2.12 ENSMUST00000062387.8
potassium inwardly-rectifying channel, subfamily J, member 9
chr3_-_92514799 2.09 ENSMUST00000195278.2
RIKEN cDNA 2210017I01 gene
chr15_-_82917495 2.08 ENSMUST00000231165.2
Nfat activating molecule with ITAM motif 1
chr6_-_73446560 2.06 ENSMUST00000070163.6
RIKEN cDNA 4931417E11 gene
chr19_-_46315543 2.04 ENSMUST00000223917.2
ENSMUST00000224447.2
ENSMUST00000041391.5
ENSMUST00000096029.12
pleckstrin and Sec7 domain containing
chr6_+_125026865 2.02 ENSMUST00000112413.8
proacrosin binding protein
chr11_+_70529944 2.00 ENSMUST00000055184.7
ENSMUST00000108551.3
glycoprotein 1b, alpha polypeptide
chr6_-_49191891 1.98 ENSMUST00000031838.9
insulin-like growth factor 2 mRNA binding protein 3
chr14_-_35533922 1.90 ENSMUST00000043266.7
RIKEN cDNA 4930596D02 gene
chr6_-_139987135 1.86 ENSMUST00000032356.13
phospholipase C, zeta 1
chr15_+_73620213 1.79 ENSMUST00000053232.8
protein tyrosine phosphatase 4a3
chr11_-_69791712 1.76 ENSMUST00000108621.9
ENSMUST00000100969.9
RIKEN cDNA 2810408A11 gene
chr11_-_69791756 1.72 ENSMUST00000018714.13
ENSMUST00000128046.2
RIKEN cDNA 2810408A11 gene
chr8_+_34007333 1.71 ENSMUST00000124496.8
testis expressed gene 15
chr19_-_28941264 1.66 ENSMUST00000161813.2
spermatogenesis associated 6 like
chr6_+_70549568 1.65 ENSMUST00000196940.2
ENSMUST00000103397.3
immunoglobulin kappa variable 3-10
chr10_+_60182630 1.65 ENSMUST00000020301.14
ENSMUST00000105460.8
ENSMUST00000170507.8
V-set immunoregulatory receptor
chr14_-_55950545 1.63 ENSMUST00000002389.9
ENSMUST00000226907.2
transglutaminase 1, K polypeptide
chr14_-_51295099 1.63 ENSMUST00000227764.2
ribonuclease, RNase A family, 12 (non-active)
chr3_+_127583450 1.63 ENSMUST00000054483.14
TRAF-interacting protein with forkhead-associated domain
chr7_+_44145987 1.62 ENSMUST00000107927.5
family with sequence similarity 71, member E1
chr15_-_89310060 1.62 ENSMUST00000109313.9
carnitine palmitoyltransferase 1b, muscle
chr11_+_6339442 1.60 ENSMUST00000109786.8
zinc finger, MIZ-type containing 2
chr9_+_95441652 1.59 ENSMUST00000079597.7
progestin and adipoQ receptor family member IX
chr6_-_122463422 1.58 ENSMUST00000068242.9
ribosomal modification protein rimK-like family member B
chr12_-_31684588 1.58 ENSMUST00000020979.9
ENSMUST00000177962.9
B cell receptor associated protein 29
chr9_-_106076389 1.57 ENSMUST00000140761.9
protein phosphatase 1M
chr4_+_9844349 1.56 ENSMUST00000057613.3
growth differentiation factor 6
chr1_-_172156828 1.56 ENSMUST00000194204.2
potassium inwardly-rectifying channel, subfamily J, member 9
chr15_-_9748863 1.55 ENSMUST00000159368.2
ENSMUST00000159093.8
ENSMUST00000162780.8
ENSMUST00000160236.8
ENSMUST00000208854.2
ENSMUST00000041840.14
sperm flagellar 2
chr3_-_92758591 1.54 ENSMUST00000054426.5
late cornified envelope 1L
chr1_+_134313676 1.54 ENSMUST00000162187.2
MGAT4 family, member F
chr1_+_132119169 1.53 ENSMUST00000188169.7
ENSMUST00000112357.9
ENSMUST00000188175.2
LEM domain containing 1
predicted gene, 29695
chr6_-_122463316 1.51 ENSMUST00000205114.2
ribosomal modification protein rimK-like family member B
chr5_-_77262968 1.51 ENSMUST00000081964.7
HOP homeobox
chr4_+_114916703 1.47 ENSMUST00000162489.2
T cell acute lymphocytic leukemia 1
chr3_+_75464837 1.47 ENSMUST00000161776.8
ENSMUST00000029423.9
serine (or cysteine) peptidase inhibitor, clade I, member 1
chr8_-_46605196 1.45 ENSMUST00000110378.9
sorting nexin 25
chr11_-_69791774 1.45 ENSMUST00000102580.10
RIKEN cDNA 2810408A11 gene
chrX_+_158623460 1.44 ENSMUST00000112451.8
ENSMUST00000112453.9
SH3-domain kinase binding protein 1
chr11_+_6339330 1.44 ENSMUST00000012612.11
zinc finger, MIZ-type containing 2
chr2_-_181333597 1.43 ENSMUST00000108778.8
ENSMUST00000165416.8
regulator of G-protein signaling 19
chr4_+_33031433 1.43 ENSMUST00000029944.13
ubiquitin-conjugating enzyme E2J 1
chr1_-_71454041 1.43 ENSMUST00000087268.7
ATP-binding cassette, sub-family A (ABC1), member 12
chr11_-_3813895 1.43 ENSMUST00000070552.14
oxysterol binding protein 2
chr4_+_154954042 1.40 ENSMUST00000079269.14
ENSMUST00000163732.8
ENSMUST00000080559.13
membrane metallo-endopeptidase-like 1
chr3_-_92922976 1.40 ENSMUST00000107301.2
ENSMUST00000029521.5
cysteine-rich C-terminal 1
chr11_-_106192627 1.40 ENSMUST00000103071.4
growth hormone
chr6_-_40562700 1.39 ENSMUST00000177178.2
ENSMUST00000129948.9
ENSMUST00000101491.11
C-type lectin domain family 5, member a
chr7_+_81823546 1.39 ENSMUST00000179318.8
SH3-domain GRB2-like 3
chr3_+_90173813 1.39 ENSMUST00000098914.10
DENN/MADD domain containing 4B
chr14_-_70855980 1.38 ENSMUST00000228001.2
dematin actin binding protein
chr11_-_87766350 1.38 ENSMUST00000049768.4
eosinophil peroxidase
chr1_-_75195889 1.37 ENSMUST00000186213.7
tubulin, alpha 4A
chr7_+_43086432 1.37 ENSMUST00000070518.4
natural killer cell group 7 sequence
chr7_-_28001624 1.36 ENSMUST00000108315.4
delta like canonical Notch ligand 3
chr15_-_89309998 1.36 ENSMUST00000168376.2
carnitine palmitoyltransferase 1b, muscle
chr3_-_75464066 1.35 ENSMUST00000162138.2
ENSMUST00000029424.12
ENSMUST00000161137.8
programmed cell death 10
chr3_+_127583550 1.33 ENSMUST00000163775.6
TRAF-interacting protein with forkhead-associated domain
chr2_-_38602207 1.33 ENSMUST00000112883.8
nuclear receptor subfamily 5, group A, member 1
chr19_-_41373526 1.32 ENSMUST00000059672.9
phosphoinositide-3-kinase adaptor protein 1
chr11_+_6339061 1.32 ENSMUST00000109787.8
zinc finger, MIZ-type containing 2
chr12_-_114057841 1.32 ENSMUST00000103471.2
ENSMUST00000195884.2
immunoglobulin heavy variable 9-1
chr7_+_43086554 1.31 ENSMUST00000206741.2
natural killer cell group 7 sequence
chr8_+_84874654 1.28 ENSMUST00000143833.8
ENSMUST00000118856.8
break repair meiotic recombinase recruitment factor 1
chr2_-_68302612 1.27 ENSMUST00000102715.4
serine/threonine kinase 39
chr1_-_132318039 1.26 ENSMUST00000132435.2
transmembrane and coiled-coil domains 2
chr9_-_62888156 1.24 ENSMUST00000098651.6
ENSMUST00000214830.2
protein inhibitor of activated STAT 1
chr10_+_56253418 1.23 ENSMUST00000068581.9
ENSMUST00000217789.2
gap junction protein, alpha 1
chr17_+_71859026 1.23 ENSMUST00000124001.8
ENSMUST00000167641.8
ENSMUST00000064420.12
speedy/RINGO cell cycle regulator family, member A
chr7_+_44146029 1.23 ENSMUST00000205359.2
family with sequence similarity 71, member E1
chr8_+_23525101 1.19 ENSMUST00000117662.8
ENSMUST00000117296.8
ENSMUST00000141784.9
ankyrin 1, erythroid
chr1_+_181404124 1.18 ENSMUST00000208001.2
dynein, axonemal, heavy chain 14
chr9_-_107109108 1.17 ENSMUST00000044532.11
dedicator of cyto-kinesis 3
chr10_+_86541675 1.17 ENSMUST00000075632.14
ENSMUST00000217747.2
ENSMUST00000061458.9
tetratricopeptide repeat domain 41
chr18_+_82932747 1.14 ENSMUST00000071233.7
zinc finger protein 516
chr15_-_99864936 1.14 ENSMUST00000100209.6
family with sequence similarity 186, member A
chr12_-_113700190 1.13 ENSMUST00000103452.3
ENSMUST00000192264.2
immunoglobulin heavy variable 5-9-1
chr7_-_25488060 1.13 ENSMUST00000002677.11
ENSMUST00000085948.11
AXL receptor tyrosine kinase
chr15_+_100659729 1.12 ENSMUST00000161564.2
solute carrier family 4 (anion exchanger), member 8
chr6_+_30639217 1.12 ENSMUST00000031806.10
carboxypeptidase A1, pancreatic
chr2_+_28403255 1.11 ENSMUST00000028170.15
ral guanine nucleotide dissociation stimulator
chr8_+_84874881 1.08 ENSMUST00000093375.5
break repair meiotic recombinase recruitment factor 1
chr11_-_23720953 1.08 ENSMUST00000102864.5
reticuloendotheliosis oncogene
chr11_+_113575208 1.08 ENSMUST00000042227.15
ENSMUST00000123466.2
ENSMUST00000106621.4
DNA segment, Chr 11, Wayne State University 47, expressed
chr1_-_92830604 1.08 ENSMUST00000160548.8
ENSMUST00000112998.2
ankyrin repeat and MYND domain containing 1
chr15_+_100659622 1.07 ENSMUST00000023776.13
solute carrier family 4 (anion exchanger), member 8
chr6_+_48695535 1.06 ENSMUST00000127537.6
ENSMUST00000052503.8
predicted gene, 28053
GTPase, IMAP family member 7
chr7_+_24990596 1.05 ENSMUST00000164820.2
capicua transcriptional repressor
chr1_+_63312420 1.04 ENSMUST00000239483.2
ENSMUST00000114132.8
ENSMUST00000126932.2
zinc finger, DBF-type containing 2
chr14_-_70414236 1.02 ENSMUST00000153735.8
PDZ and LIM domain 2
chr7_-_101749433 1.02 ENSMUST00000106937.8
ADP-ribosyltransferase 5
chr12_-_113823290 1.01 ENSMUST00000103459.5
immunoglobulin heavy variable 5-17
chr2_-_91013193 1.01 ENSMUST00000111370.9
ENSMUST00000111376.8
ENSMUST00000099723.9
MAP-kinase activating death domain
chr7_+_81508741 1.00 ENSMUST00000041890.8
transmembrane 6 superfamily member 1
chr19_+_23881821 1.00 ENSMUST00000237688.2
amyloid beta (A4) precursor protein binding, family A, member 1
chr5_-_148336711 0.98 ENSMUST00000048116.15
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr2_-_144174066 0.98 ENSMUST00000037423.4
ovo like zinc finger 2
chr6_-_84564623 0.97 ENSMUST00000205228.3
cytochrome P450, family 26, subfamily b, polypeptide 1
chr13_-_113317431 0.97 ENSMUST00000038212.14
granzyme K
chr11_+_54194831 0.97 ENSMUST00000000145.12
ENSMUST00000138515.8
acyl-CoA synthetase long-chain family member 6
chr4_+_132291369 0.96 ENSMUST00000070690.8
platelet-activating factor receptor
chr5_+_98328723 0.96 ENSMUST00000112959.4
PR domain containing 8
chr8_+_34006758 0.96 ENSMUST00000149399.8
testis expressed gene 15
chr11_+_115044966 0.96 ENSMUST00000021076.6
RAB37, member RAS oncogene family
chr12_+_69954506 0.96 ENSMUST00000223456.2
atlastin GTPase 1
chr6_-_84564972 0.96 ENSMUST00000204109.2
cytochrome P450, family 26, subfamily b, polypeptide 1
chr4_+_33031342 0.96 ENSMUST00000124992.8
ubiquitin-conjugating enzyme E2J 1
chr6_+_35229628 0.95 ENSMUST00000130875.8
RIKEN cDNA 1810058I24 gene
chr7_-_109037992 0.95 ENSMUST00000121748.8
serine/threonine kinase 33
chrX_+_73220858 0.95 ENSMUST00000010127.12
transketolase-like 1
chr11_+_54195006 0.94 ENSMUST00000108904.10
ENSMUST00000108905.10
acyl-CoA synthetase long-chain family member 6
chr1_-_161616031 0.94 ENSMUST00000000834.4
Fas ligand (TNF superfamily, member 6)
chr1_+_9868332 0.93 ENSMUST00000166384.8
ENSMUST00000168907.8
serum/glucocorticoid regulated kinase 3
chr10_+_84412490 0.93 ENSMUST00000020223.8
t-complex 11 (mouse) like 2
chr15_+_103411689 0.92 ENSMUST00000226493.2
phosphodiesterase 1B, Ca2+-calmodulin dependent
chr17_-_7620095 0.92 ENSMUST00000115747.3
tubulin tyrosine ligase-like family, member 2
chr9_-_20978389 0.92 ENSMUST00000115494.3
zinc finger, GATA-like protein 1
chr4_+_83443777 0.91 ENSMUST00000053414.13
ENSMUST00000231339.2
ENSMUST00000126429.8
coiled-coil domain containing 171
chr7_-_109038282 0.91 ENSMUST00000106745.9
ENSMUST00000090414.11
ENSMUST00000141210.2
serine/threonine kinase 33
chr3_+_92315290 0.90 ENSMUST00000047264.3
small proline-rich protein 2I
chr3_-_37180093 0.90 ENSMUST00000029275.6
interleukin 2
chr7_-_27095964 0.89 ENSMUST00000108363.8
spectrin beta, non-erythrocytic 4
chrX_+_99669343 0.88 ENSMUST00000048962.4
kinesin family member 4
chr4_-_43045685 0.88 ENSMUST00000107956.8
ENSMUST00000107957.8
family with sequence similarity 214, member B
chr15_-_75760602 0.87 ENSMUST00000184858.2
maestro heat-like repeat family member 6
chr7_-_109038202 0.86 ENSMUST00000121378.2
serine/threonine kinase 33
chrX_-_59498719 0.85 ENSMUST00000114687.9
predicted gene 7073
chr4_-_133329479 0.85 ENSMUST00000057311.4
stratifin
chr15_-_100583044 0.84 ENSMUST00000230312.2
chymotrypsin-like elastase family, member 1
chr17_+_47815968 0.84 ENSMUST00000182129.8
ENSMUST00000171031.8
cyclin D3
chr7_+_89779564 0.83 ENSMUST00000208742.2
ENSMUST00000049537.9
phosphatidylinositol binding clathrin assembly protein
chr7_-_19595221 0.83 ENSMUST00000014830.8
carcinoembryonic antigen-related cell adhesion molecule 16
chr17_-_32255287 0.82 ENSMUST00000238192.2
heat shock transcription factor 2 binding protein
chr13_+_13764982 0.82 ENSMUST00000110559.3
lysosomal trafficking regulator
chrX_+_41578568 0.82 ENSMUST00000197237.2
TEX13 family member C2
chr5_-_142892457 0.81 ENSMUST00000167721.8
ENSMUST00000163829.2
ENSMUST00000100497.11
actin, beta
chr1_-_74323795 0.81 ENSMUST00000178235.8
ENSMUST00000006462.14
angio-associated migratory protein
chr7_-_112968533 0.81 ENSMUST00000047091.14
ENSMUST00000119278.8
BTB (POZ) domain containing 10
chr11_-_82761954 0.81 ENSMUST00000108173.10
ENSMUST00000071152.14
ring finger and FYVE like domain containing protein
chr10_+_80538115 0.80 ENSMUST00000218184.2
IZUMO family member 4
chr12_-_113733922 0.80 ENSMUST00000180013.3
immunoglobulin heavy variable 2-9-1
chr19_-_37184692 0.79 ENSMUST00000132580.8
ENSMUST00000079754.11
ENSMUST00000136286.8
ENSMUST00000126188.8
ENSMUST00000126781.2
cytoplasmic polyadenylation element binding protein 3
chr11_-_46203047 0.79 ENSMUST00000129474.2
ENSMUST00000093166.11
ENSMUST00000165599.9
cytoplasmic FMR1 interacting protein 2
chr1_+_74640706 0.79 ENSMUST00000087186.11
serine/threonine kinase 36
chr17_+_47816074 0.79 ENSMUST00000183177.8
ENSMUST00000182848.8
cyclin D3
chr1_+_132243849 0.79 ENSMUST00000072177.14
ENSMUST00000082125.6
NUAK family, SNF1-like kinase, 2
chr1_+_74640590 0.78 ENSMUST00000087183.11
ENSMUST00000148456.8
ENSMUST00000113694.8
serine/threonine kinase 36
chr7_+_44146012 0.78 ENSMUST00000205422.2
family with sequence similarity 71, member E1
chr17_+_47816042 0.77 ENSMUST00000183044.8
ENSMUST00000037333.17
cyclin D3
chr7_+_19197192 0.77 ENSMUST00000137613.9
exocyst complex component 3-like 2
chr7_-_24771717 0.76 ENSMUST00000003468.10
glutamate receptor, ionotropic, kainate 5 (gamma 2)
chr10_+_69048506 0.76 ENSMUST00000167384.8
Rho-related BTB domain containing 1
chr1_-_167112784 0.75 ENSMUST00000053686.9
uridine-cytidine kinase 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 5.9 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
1.1 3.3 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
1.0 1.0 GO:1902941 regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943)
0.9 10.0 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.7 4.0 GO:0010587 miRNA catabolic process(GO:0010587)
0.6 2.5 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.5 9.2 GO:0090527 actin filament reorganization(GO:0090527)
0.5 1.6 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.5 3.9 GO:0007341 penetration of zona pellucida(GO:0007341)
0.5 1.5 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.5 1.4 GO:0035627 ceramide transport(GO:0035627)
0.5 2.8 GO:2000224 regulation of testosterone biosynthetic process(GO:2000224)
0.5 1.4 GO:0002215 defense response to nematode(GO:0002215)
0.4 1.3 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.4 1.3 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.4 2.5 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.4 1.2 GO:0010232 vascular transport(GO:0010232) milk ejection(GO:0060156)
0.4 1.6 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.4 1.9 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.3 2.7 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.3 1.3 GO:0048388 endosomal lumen acidification(GO:0048388)
0.3 1.9 GO:2001037 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.3 5.0 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.3 12.2 GO:0048240 sperm capacitation(GO:0048240)
0.3 0.8 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.3 0.8 GO:1903433 regulation of constitutive secretory pathway(GO:1903433)
0.3 1.4 GO:0007386 compartment pattern specification(GO:0007386)
0.3 0.8 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.3 0.8 GO:1900247 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.2 0.7 GO:0032262 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206) CMP metabolic process(GO:0046035)
0.2 1.6 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.2 1.6 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.2 2.5 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.2 1.1 GO:0097048 dendritic cell apoptotic process(GO:0097048) neutrophil clearance(GO:0097350) regulation of dendritic cell apoptotic process(GO:2000668)
0.2 1.3 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.2 2.4 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.2 2.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.2 0.8 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2 1.3 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.2 5.5 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.2 0.7 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.2 0.8 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 0.8 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.2 0.5 GO:1904582 positive regulation of intracellular mRNA localization(GO:1904582)
0.1 0.6 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.1 0.8 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 1.5 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.1 0.8 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 3.3 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 1.5 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 1.9 GO:0007343 egg activation(GO:0007343)
0.1 1.0 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.1 0.8 GO:0060309 elastin catabolic process(GO:0060309)
0.1 1.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 1.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 4.4 GO:0030261 chromosome condensation(GO:0030261)
0.1 1.8 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.1 0.3 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.1 5.0 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.1 0.9 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 1.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 0.6 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.1 0.7 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 0.5 GO:0018992 germ-line sex determination(GO:0018992)
0.1 1.5 GO:0003351 epithelial cilium movement(GO:0003351)
0.1 0.7 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 1.5 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.6 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.9 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 1.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.3 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.2 GO:0046203 spermidine catabolic process(GO:0046203)
0.1 0.9 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.1 0.7 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 0.4 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 0.4 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.1 2.3 GO:0031424 keratinization(GO:0031424)
0.1 0.4 GO:0034184 positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.1 0.2 GO:0036245 cellular response to menadione(GO:0036245)
0.1 0.6 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 2.6 GO:0007340 acrosome reaction(GO:0007340)
0.1 0.6 GO:0010815 bradykinin catabolic process(GO:0010815)
0.1 0.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.9 GO:0015809 arginine transport(GO:0015809)
0.1 0.2 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.1 1.4 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.1 0.3 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 1.3 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.5 GO:0046642 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.5 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 1.3 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.0 0.8 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.1 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 1.1 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 6.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.3 GO:0021815 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
0.0 2.0 GO:0010107 potassium ion import(GO:0010107)
0.0 1.0 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.7 GO:0021540 corpus callosum morphogenesis(GO:0021540)
0.0 1.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.5 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 1.9 GO:0018149 peptide cross-linking(GO:0018149)
0.0 1.7 GO:0046039 GTP metabolic process(GO:0046039)
0.0 0.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0070543 response to linoleic acid(GO:0070543)
0.0 1.2 GO:0048821 erythrocyte development(GO:0048821)
0.0 0.3 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 2.4 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 0.4 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.3 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.2 GO:0002432 granuloma formation(GO:0002432)
0.0 1.3 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.3 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.3 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 1.2 GO:0007140 male meiosis(GO:0007140)
0.0 0.6 GO:0034389 lipid particle organization(GO:0034389)
0.0 3.4 GO:0007286 spermatid development(GO:0007286)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.0 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.3 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.4 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.4 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 1.3 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 2.2 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.8 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.9 GO:0048599 oocyte development(GO:0048599)
0.0 1.1 GO:0009409 response to cold(GO:0009409)
0.0 0.1 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.4 GO:0030204 chondroitin sulfate metabolic process(GO:0030204)
0.0 0.4 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.2 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.2 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.4 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.6 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.4 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.0 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 2.1 GO:0051028 mRNA transport(GO:0051028)
0.0 0.8 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.0 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0048515 spermatid differentiation(GO:0048515)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.0 GO:1901026 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.0 0.3 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.0 0.1 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.0 0.4 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.2 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 2.7 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 2.2 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.2 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0033193 Lsd1/2 complex(GO:0033193)
0.5 1.5 GO:0034774 secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.5 6.8 GO:0036128 CatSper complex(GO:0036128)
0.4 4.1 GO:0002177 manchette(GO:0002177)
0.3 4.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.3 1.4 GO:0097209 epidermal lamellar body(GO:0097209)
0.2 2.9 GO:0000801 central element(GO:0000801)
0.2 1.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 2.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 9.2 GO:0001772 immunological synapse(GO:0001772)
0.1 4.4 GO:0000786 nucleosome(GO:0000786)
0.1 0.8 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.9 GO:0008091 spectrin(GO:0008091)
0.1 0.4 GO:0035061 interchromatin granule(GO:0035061)
0.1 0.8 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 4.7 GO:0043596 nuclear replication fork(GO:0043596)
0.1 1.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 1.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.6 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.7 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 2.2 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 1.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 1.2 GO:0005916 fascia adherens(GO:0005916)
0.1 0.3 GO:0043293 apoptosome(GO:0043293)
0.1 0.4 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 1.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 6.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.6 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 2.4 GO:0001533 cornified envelope(GO:0001533)
0.0 3.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.4 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 1.1 GO:0033643 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.0 0.3 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 1.0 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.3 GO:0044327 dendritic spine head(GO:0044327)
0.0 1.4 GO:0097440 apical dendrite(GO:0097440)
0.0 3.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 3.2 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 4.6 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 1.5 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 1.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.4 GO:0042581 specific granule(GO:0042581)
0.0 1.2 GO:0030286 dynein complex(GO:0030286)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 3.4 GO:0005884 actin filament(GO:0005884)
0.0 4.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 3.1 GO:0031514 motile cilium(GO:0031514)
0.0 0.4 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 2.8 GO:0030141 secretory granule(GO:0030141)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 4.9 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 5.5 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 7.8 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.8 3.1 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.5 1.4 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.4 3.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 3.3 GO:0045545 syndecan binding(GO:0045545)
0.3 1.3 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.3 1.9 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.3 0.9 GO:0004802 transketolase activity(GO:0004802)
0.3 4.0 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.3 0.8 GO:0098918 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.2 3.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 1.3 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.2 1.5 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.2 5.0 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.2 1.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 2.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 1.2 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.2 1.0 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.2 1.6 GO:0008420 CTD phosphatase activity(GO:0008420)
0.2 1.4 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 0.9 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.4 GO:0050354 glycerone kinase activity(GO:0004371) FAD-AMP lyase (cyclizing) activity(GO:0034012) triokinase activity(GO:0050354)
0.1 0.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.4 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 5.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 1.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 3.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.7 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.7 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 2.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.9 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 2.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.9 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 2.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.9 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.4 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 0.6 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 1.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 5.9 GO:0070888 E-box binding(GO:0070888)
0.1 0.4 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 2.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 1.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 3.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.6 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.4 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.5 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467) very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 1.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 3.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 0.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.8 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.2 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 3.2 GO:0050699 WW domain binding(GO:0050699)
0.1 4.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 2.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 1.3 GO:0005123 death receptor binding(GO:0005123)
0.0 6.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.0 0.3 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 2.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.3 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.6 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.9 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 1.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 1.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.7 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 1.9 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.6 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.6 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 1.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 2.1 GO:0030507 spectrin binding(GO:0030507)
0.0 4.4 GO:0002020 protease binding(GO:0002020)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.2 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 2.4 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 1.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 2.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 4.2 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 4.3 GO:0003924 GTPase activity(GO:0003924)
0.0 0.1 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.2 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 0.9 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.4 GO:0004540 ribonuclease activity(GO:0004540)
0.0 1.2 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.0 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 1.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.3 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 1.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 1.3 PID TNF PATHWAY TNF receptor signaling pathway
0.1 2.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 4.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 3.9 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 1.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 3.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 3.6 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.5 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 2.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 3.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 3.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 2.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.9 PID NOTCH PATHWAY Notch signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.1 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 3.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 2.9 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 1.1 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 1.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 3.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 3.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 1.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 2.9 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.9 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.4 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.8 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 3.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.4 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 5.4 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade